Len A. Pennacchio | Academic Influence

Len A. Pennacchio's AcademicInfluence.com Rankings

Len A. Pennacchio

Biology

#7854

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#10838

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Computational Biology

#280

World Rank

#281

Historical Rank

Genetics

#781

World Rank

#873

Historical Rank

Molecular Biology

#2093

World Rank

#2125

Historical Rank

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Biology

Len A. Pennacchio's Degrees

Bachelors Biology University of California, Berkeley
PhD Genetics Stanford University

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Why Is Len A. Pennacchio Influential?

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According to Wikipedia, Len A. Pennacchio is an American molecular biologist, the head of the Genetic Analysis Program and the Genomic Technologies Program at the Joint Genome Institute in Walnut Creek, California. Pennacchio did his undergraduate studies at Sonoma State University and then went on to graduate studies at Stanford University, receiving a Ph.D. in genetics in 1998. He became a research scientist at the Lawrence Berkeley National Laboratory in 1999, and joined the Joint Genome Institute in 2003. He retains his Lawrence Berkeley affiliation as well.

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Len A. Pennacchio's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease (2008) (2629)
ChIP-seq accurately predicts tissue-specific activity of enhancers (2009) (1636)
The amphioxus genome and the evolution of the chordate karyotype (2008) (1517)
A Common Allele on Chromosome 9 Associated with Coronary Heart Disease (2007) (1497)
Guidelines for investigating causality of sequence variants in human disease (2014) (1160)
Metagenomic Discovery of Biomass-Degrading Genes and Genomes from Cow Rumen (2011) (1142)
In vivo enhancer analysis of human conserved non-coding sequences (2006) (1141)
VISTA Enhancer Browser—a database of tissue-specific human enhancers (2006) (940)
An Apolipoprotein Influencing Triglycerides in Humans and Mice Revealed by Comparative Sequencing (2001) (923)
Expanded encyclopaedias of DNA elements in the human and mouse genomes (2020) (765)
Dicer, Drosha, and outcomes in patients with ovarian cancer. (2008) (708)
Gain-of-function RAF1 mutations cause Noonan and LEOPARD syndromes with hypertrophic cardiomyopathy (2007) (615)
Most rare missense alleles are deleterious in humans: implications for complex disease and association studies. (2007) (598)
Genomic Views of Distant-Acting Enhancers (2009) (594)
Chromatin stretch enhancer states drive cell-specific gene regulation and harbor human disease risk variants (2013) (577)
Gain-of-function SOS1 mutations cause a distinctive form of Noonan syndrome (2006) (561)
Population-based resequencing of ANGPTL4 uncovers variations that reduce triglycerides and increase HDL (2007) (531)
Targeted Deletion of the 9p21 Noncoding Coronary Artery Disease Risk Interval in Mice (2010) (494)
Mutations in the Gene Encoding Cystatin B in Progressive Myoclonus Epilepsy (EPM1) (1996) (488)
The amphioxus genome illuminates vertebrate origins and cephalochordate biology. (2008) (484)
Massively parallel functional dissection of mammalian enhancers in vivo (2012) (483)
Enhancers: five essential questions (2013) (462)
ChIP-Seq identification of weakly conserved heart enhancers (2010) (447)
Genomic strategies to identify mammalian regulatory sequences (2001) (418)
Two independent apolipoprotein A5 haplotypes influence human plasma triglyceride levels. (2002) (415)
Relative contribution of variation within the APOC3/A4/A5 gene cluster in determining plasma triglycerides. (2002) (399)
Rare loss-of-function mutations in ANGPTL family members contribute to plasma triglyceride levels in humans. (2008) (377)
Disruption of an AP-2α binding site in an IRF6 enhancer is strongly associated with cleft lip (2008) (355)
Human-Specific Gain of Function in a Developmental Enhancer (2008) (337)
Ultraconservation identifies a small subset of extremely constrained developmental enhancers (2008) (332)
Rapid and Pervasive Changes in Genome-wide Enhancer Usage during Mammalian Development (2013) (327)
Progressive ataxia, myoclonic epilepsy and cerebellar apoptosis in cystatin B-deficient mice (1998) (325)
Enhancer Redundancy Allows for Phenotypic Robustness in Mammalian Development (2017) (324)
Combinatorial Regulation of Endothelial Gene Expression by Ets and Forkhead Transcription Factors (2008) (323)
Deletion of Ultraconserved Elements Yields Viable Mice (2007) (309)
Integrated analysis of homozygous deletions, focal amplifications, and sequence alterations in breast and colorectal cancers (2008) (300)
Cathepsin L is required for endothelial progenitor cell–induced neovascularization (2005) (300)
The DNA sequence and biology of human chromosome 19 (2004) (295)
A restricted spectrum of NRAS mutations causes Noonan syndrome (2010) (279)
Genetic dissection of the α-globin super-enhancer in vivo (2016) (264)
Mutation of SHOC2 promotes aberrant protein N-myristoylation and causes Noonan-like syndrome with loose anagen hair (2009) (254)
Large-Scale Discovery of Enhancers from Human Heart Tissue (2011) (253)
Genomic Patterns of De Novo Mutation in Simplex Autism (2017) (247)
The Epigenomic Landscape of Prokaryotes (2016) (245)
A High-Resolution Enhancer Atlas of the Developing Telencephalon (2013) (244)
Single-nucleus analysis of accessible chromatin in developing mouse forebrain reveals cell-type-specific transcriptional regulation (2018) (238)
Principles of regulatory information conservation between mouse and human (2014) (232)
Medical sequencing at the extremes of human body mass. (2006) (228)
Unstable minisatellite expansion causing recessively inherited myoclonus epilepsy, EPM1 (1997) (227)
Mutation in SHOC2 promotes aberrant protein N-myristoylation and underlies Noonan-like syndrome with loose anagen hair (2009) (226)
Fine Tuning of Craniofacial Morphology by Distant-Acting Enhancers (2013) (218)
Apolipoprotein A5, a Crucial Determinant of Plasma Triglyceride Levels, Is Highly Responsive to Peroxisome Proliferator-activated Receptor α Activators* (2003) (217)
Homotypic clusters of transcription factor binding sites are a key component of human promoters and enhancers. (2010) (217)
Progressive Loss of Function in a Limb Enhancer during Snake Evolution (2016) (213)
Mechanism of triglyceride lowering in mice expressing human apolipoprotein A5. (2004) (209)
Apolipoprotein AV Accelerates Plasma Hydrolysis of Triglyceriderich Lipoproteins by Interaction with Proteoglycan-bound Lipoprotein Lipase* (2005) (205)
Tracking the roots of cellulase hyperproduction by the fungus Trichoderma reesei using massively parallel DNA sequencing (2009) (197)
Close sequence comparisons are sufficient to identify human cis-regulatory elements. (2005) (195)
De novo Identification of DNA Modifications Enabled by Genome-Guided Nanopore Signal Processing (2017) (187)
An atlas of dynamic chromatin landscapes in mouse fetal development (2020) (172)
Germline Chd8 haploinsufficiency alters brain development in mouse (2017) (169)
Apolipoprotein A5, a newly identified gene that affects plasma triglyceride levels in humans and mice. (2003) (167)
Genome resequencing reveals multiscale geographic structure and extensive linkage disequilibrium in the forest tree Populus trichocarpa. (2012) (163)
The sequence and analysis of duplication-rich human chromosome 16 (2004) (160)
Apoa5 Q139X truncation predisposes to late-onset hyperchylomicronemia due to lipoprotein lipase impairment. (2005) (158)
Dlx1&2-Dependent Expression of Zfhx1b (Sip1, Zeb2) Regulates the Fate Switch between Cortical and Striatal Interneurons (2013) (150)
Ultraconserved Enhancers Are Required for Normal Development (2018) (147)
Comparative genomic analysis as a tool for biological discovery (2003) (145)
Predicting tissue-specific enhancers in the human genome. (2006) (143)
Apolipoprotein AV accelerates plasma hydrolysis of triglyceride-rich lipoproteins by interaction with proteoglycan-bound lipoprotein lipase. (2005) (128)
Lack of MEF2A mutations in coronary artery disease. (2005) (127)
Dynamic GATA4 enhancers shape the chromatin landscape central to heart development and disease (2014) (126)
Apolipoprotein A-V Deficiency Results in Marked Hypertriglyceridemia Attributable to Decreased Lipolysis of Triglyceride-Rich Lipoproteins and Removal of Their Remnants (2005) (125)
Association of functionally significant Melanocortin-4 but not Melanocortin-3 receptor mutations with severe adult obesity in a large North American case-control study. (2009) (125)
Directed Evolution of Ionizing Radiation Resistance in Escherichia coli (2009) (121)
Enhancer identification through comparative genomics. (2006) (120)
Functional importance of cardiac enhancer-associated noncoding RNAs in heart development and disease (2014) (118)
The DNA sequence and comparative analysis of human chromosome 5 (2004) (116)
Insulin-Mediated Down-Regulation of Apolipoprotein A5 Gene Expression through the Phosphatidylinositol 3-Kinase Pathway: Role of Upstream Stimulatory Factor (2005) (114)
Tissue-Specific RNA Expression Marks Distant-Acting Developmental Enhancers (2014) (109)
Cathepsin B but not cathepsins L or S contributes to the pathogenesis of Unverricht-Lundborg progressive myoclonus epilepsy (EPM1). (2003) (108)
Haplotype analysis of the apolipoprotein gene cluster on human chromosome 11. (2004) (105)
Linkage and Association Between Distinct Variants of the APOA1/C3/A4/A5 Gene Cluster and Familial Combined Hyperlipidemia (2004) (105)
Array comparative genomic hybridization in patients with congenital diaphragmatic hernia: mapping of four CDH-critical regions and sequencing of candidate genes at 15q26.1–15q26.2 (2006) (103)
Cystatin B-deficient mice have increased expression of apoptosis and glial activation genes. (2001) (103)
A large genomic deletion leads to enhancer adoption by the lamin B1 gene: a second path to autosomal dominant adult-onset demyelinating leukodystrophy (ADLD) (2015) (103)
Enhancer Variants Synergistically Drive Dysfunction of a Gene Regulatory Network In Hirschsprung Disease (2016) (103)
Occupancy by key transcription factors is a more accurate predictor of enhancer activity than histone modifications or chromatin accessibility (2015) (102)
52 Genetic Loci Influencing Myocardial Mass. (2016) (98)
In vivo characterization of a vertebrate ultraconserved enhancer. (2005) (96)
The changing mouse embryo transcriptome at whole tissue and single-cell resolution (2020) (96)
Genome Sequence of “Candidatus Frankia datiscae” Dg1, the Uncultured Microsymbiont from Nitrogen-Fixing Root Nodules of the Dicot Datisca glomerata (2011) (91)
The Liver X Receptor Ligand T0901317 Down-regulates APOA5 Gene Expression through Activation of SREBP-1c* (2004) (89)
A Cryptochrome 2 mutation yields advanced sleep phase in humans (2016) (88)
Somatic mutations of GUCY2F, EPHA3, and NTRK3 in human cancers (2006) (87)
Brg1 modulates enhancer activation in mesoderm lineage commitment (2015) (84)
Genome-wide compendium and functional assessment of in vivo heart enhancers (2016) (83)
Comprehensive identification and analysis of human accelerated regulatory DNA (2015) (82)
Analysis of Apolipoprotein A5, C3, and Plasma Triglyceride Concentrations in Genetically Engineered Mice (2004) (82)
Association of common variants in the Joubert syndrome gene (AHI1) with autism. (2008) (82)
Transcriptional Regulation of Enhancers Active in Protodomains of the Developing Cerebral Cortex (2014) (81)
Gain-of-Function R225W Mutation in Human AMPKγ3 Causing Increased Glycogen and Decreased Triglyceride in Skeletal Muscle (2007) (81)
Comparative genomic tools and databases: providing insights into the human genome. (2003) (80)
Insights from human/mouse genome comparisons (2003) (80)
Perspectives on ENCODE (2020) (79)
Function-based Identification of Mammalian Enhancers Using Site-Specific Integration (2014) (79)
Activating Mutations Affecting the Dbl Homology Domain of SOS2 Cause Noonan Syndrome (2015) (71)
Comprehensive In Vivo Interrogation Reveals Phenotypic Impact of Human Enhancer Variants (2020) (70)
Enhancer redundancy provides phenotypic robustness in mammalian development (2018) (69)
Apolipoprotein AIV Gene Variant S347 Is Associated With Increased Risk of Coronary Heart Disease and Lower Plasma Apolipoprotein AIV Levels (2003) (68)
The complete sequence of human chromosome 5 (2004) (68)
Identification of Novel Craniofacial Regulatory Domains Located far Upstream of SOX9 and Disrupted in Pierre Robin Sequence (2014) (68)
Evolution of extreme resistance to ionizing radiation via genetic adaptation of DNA repair (2013) (67)
Improved regulatory element prediction based on tissue-specific local epigenomic signatures (2017) (66)
Functional autonomy of distant-acting human enhancers. (2009) (66)
Massively parallel sequencing identifies the gene Megf8 with ENU-induced mutation causing heterotaxy (2009) (63)
Tissue-specific SMARCA4 binding at active and repressed regulatory elements during embryogenesis (2014) (63)
Lack of Support for the Association between GAD2 Polymorphisms and Severe Human Obesity (2005) (60)
Spatiotemporal DNA methylome dynamics of the developing mouse fetus (2020) (58)
Construction of a 750-kb bacterial clone contig and restriction map in the region of human chromosome 21 containing the progressive myoclonus epilepsy gene. (1996) (56)
An etiologic regulatory mutation in IRF6 with loss- and gain-of-function effects. (2014) (54)
The molecular genetic bases of the progressive myoclonus epilepsies. (1999) (53)
Phylo-VISTA: interactive visualization of multiple DNA sequence alignments (2004) (52)
Complete genome sequence of Dehalogenimonas lykanthroporepellens type strain (BL-DC-9T) and comparison to “Dehalococcoides” strains (2012) (52)
Transcriptional Regulation of Apolipoprotein A5 Gene Expression by the Nuclear Receptor RORα (2005) (52)
Relationship between genetic variation at PPP1R3B and levels of liver glycogen and triglyceride (2018) (49)
Genomic Resolution of DLX-Orchestrated Transcriptional Circuits Driving Development of Forebrain GABAergic Neurons (2019) (47)
Human cathepsin L rescues the neurodegeneration and lethality in cathepsin B/L double-deficient mice (2006) (46)
Supervised enhancer prediction with epigenetic pattern recognition and targeted validation (2018) (44)
Isolation and characterization of the mouse cystatin B gene. (1996) (43)
Complete genome sequence of Nitrosomonas sp. Is79, an ammonia oxidizing bacterium adapted to low ammonium concentrations (2013) (41)
Functional anatomy of distant-acting mammalian enhancers (2013) (39)
Genetic and functional analyses identify DISC1 as a novel callosal agenesis candidate gene (2011) (37)
A PYY Q62P variant linked to human obesity. (2006) (36)
Haplotypes in the APOA1-C3-A4-A5 gene cluster affect plasma lipids in both humans and baboons. (2004) (35)
Finishing The Euchromatic Sequence Of The Human Genome (2004) (35)
Congenital Heart Defects in Patients with Deletions Upstream of SOX9 (2013) (35)
Presynaptic Homeostasis Opposes Disease Progression in Mouse Models of ALS-Like Degeneration: Evidence for Homeostatic Neuroprotection (2020) (33)
TIMELESS mutation alters phase responsiveness and causes advanced sleep phase (2019) (33)
Edinburgh Research Explorer Disruption of an AP-2alpha binding site in an IRF6 enhancer is associated with cleft lip (2018) (33)
In vivo characterization of human APOA5 haplotypes. (2007) (32)
Systematic mapping of chromatin state landscapes during mouse development (2017) (31)
Use of “MGE Enhancers” for Labeling and Selection of Embryonic Stem Cell-Derived Medial Ganglionic Eminence (MGE) Progenitors and Neurons (2013) (31)
A Genetic Signature of Spina Bifida Risk from Pathway-Informed Comprehensive Gene-Variant Analysis (2011) (29)
Brg1 coordinates multiple processes during retinogenesis and is a tumor suppressor in retinoblastoma (2015) (28)
Generation of Long Insert Pairs Using a Cre-LoxP Inverse PCR Approach (2012) (28)
SNP-VISTA: An interactive SNP visualization tool (2005) (28)
Genome Sequence of Kosmotoga olearia Strain TBF 19.5.1, a Thermophilic Bacterium with a Wide Growth Temperature Range, Isolated from the Troll B Oil Platform in the North Sea (2011) (28)
Identification of a novel enhancer of brain expression near the apoE gene cluster by comparative genomics. (2004) (27)
Complete Genome Sequence of the Marine Cellulose- and Xylan-Degrading Bacterium Glaciecolasp. Strain 4H-3-7+YE-5 (2011) (25)
1001 Proteomes: a functional proteomics portal for the analysis of Arabidopsis thaliana accessions (2012) (24)
Complete genome sequence of Parvibaculum lavamentivorans type strain (DS-1T) (2011) (24)
Parkinson-associated SNCA enhancer variants revealed by open chromatin in mouse dopamine neurons (2018) (24)
ATAC-Seq Reveals an Isl1 Enhancer That Regulates Sinoatrial Node Development and Function (2020) (24)
Dynamic BAF chromatin remodeling complex subunit inclusion promotes temporally distinct gene expression programs in cardiogenesis (2019) (24)
Spatiotemporal DNA Methylome Dynamics of the Developing Mammalian Fetus (2017) (23)
Characterization of the human neurocan gene, CSPG3. (1998) (22)
High-Quality Draft Genome Sequence of the Opitutaceae Bacterium Strain TAV1, a Symbiont of the Wood-Feeding Termite Reticulitermes flavipes (2012) (21)
Ultraconserved enhancer function does not require perfect sequence conservation (2021) (21)
Differences in enhancer activity in mouse and zebrafish reporter assays are often associated with changes in gene expression (2012) (21)
Genome Sequence of Thermotoga sp. Strain RQ2, a Hyperthermophilic Bacterium Isolated from a Geothermally Heated Region of the Seafloor near Ribeira Quente, the Azores (2011) (20)
Glucose regulates the expression of the apolipoprotein A5 gene. (2008) (19)
Comparative genomic analysis reveals a distant liver enhancer upstream of the COUP-TFII gene (2005) (19)
The INSIG2 rs7566605 genetic variant does not play a major role in obesity in a sample of 24,722 individuals from four cohorts (2009) (19)
Complete Genome Sequences of Krokinobactersp. Strain 4H-3-7-5 and Lacinutrixsp. Strain 5H-3-7-4, Polysaccharide-Degrading Members of the Family Flavobacteriaceae (2011) (17)
Limb-Enhancer Genie: An accessible resource of accurate enhancer predictions in the developing limb (2017) (17)
Noncoding Deletions Expose a Novel Gene Critical for Intestinal Function (2019) (16)
Response to Comment on "Human-Specific Gain of Function in a Developmental Enhancer" (2009) (16)
Genome-wide fetalization of enhancer architecture in heart disease (2019) (16)
Single site-specific integration targeting coupled with embryonic stem cell differentiation provides a high-throughput alternative to in vivo enhancer analyses (2013) (15)
Long-read metagenomics of soil communities reveals phylum-specific secondary metabolite dynamics (2021) (15)
Complete Genome Sequence of Rahnella aquatilis CIP 78.65 (2012) (15)
Limits of sequence and functional conservation (2010) (15)
Genome Sequence of the Mercury-Methylating and Pleomorphic Desulfovibrio africanus Strain Walvis Bay (2011) (15)
Reactivation of a developmentally silenced embryonic globin gene (2021) (14)
Apolipoprotein A 5 , a Newly Identified Gene That Affects Plasma Triglyceride Levels in Humans and Mice (2003) (14)
Structure, sequence and location of the UQCRFS1 gene for the human Rieske Fe-S protein. (1995) (12)
Transcriptional Regulation of Apolipoprotein A5 Gene Expression by theNuclear Receptor ROR alpha (2004) (12)
Cooperative activation of cardiac transcription through myocardin bridging of paired MEF2 sites (2017) (12)
Complete genome sequence of Parvibaculum lavamentivorans type strain (DS-1) (2012) (10)
Complete Genome Sequence of Rahnella sp. Strain Y9602, a Gammaproteobacterium Isolate from Metal- and Radionuclide-Contaminated Soil (2012) (10)
Coding and noncoding variants in EBF3 are involved in HADDS and simplex autism (2021) (9)
Complete genome sequence of Desulfurispirillum indicum strain S5T (2011) (9)
Phylo-VISTA: An Interactive Visualization Tool for Multiple DNA Sequence Alignments (2003) (8)
Single-nucleus analysis of accessible chromatin in developing mouse forebrain reveals cell-type-specific transcriptional regulation (2018) (6)
Perfect and imperfect views of ultraconserved sequences (2021) (6)
Stable enhancers are active in development, and fragile enhancers are associated with evolutionary adaptation (2019) (6)
Topologically Associating Domain Boundaries are Commonly Required for Normal Genome Function (2021) (5)
Human-mouse comparative genomics: successes and failures to reveal functional regions of the human genome. (2003) (5)
3P-0816∗ Apolipoprotein A5 is an inflammatory responsive gene down-regulated by tumor necrosis factorα and interleukin-1 (2003) (5)
Apolipoprotein A5 is an inflammatory responsive gene down-regulated by tumor necrosis factor alpha and interleukin-1 (2004) (4)
Comparative genomics: a tool to functionally annotate human DNA. (2007) (4)
Contrasting Patterns of Sequence Evolution at the Functionally Redundant bric à brac Paralogs in Drosophila melanogaster (2009) (4)
Widespread Increase in Enhancer—Promoter Interactions during Developmental Enhancer Activation in Mammals (2022) (4)
Deletion of a non-canonical regulatory sequence causes loss of Scn1a expression and epileptic phenotypes in mice (2021) (4)
Deletion of a non-canonical promoter regulatory element causes loss of Scn1a expression and epileptic phenotypes in mice (2019) (4)
Miscues on the “ lack of MEF 2 A mutations ” in coronary artery disease (2005) (4)
Characterization of Mammalian In Vivo Enhancers Using Mouse Transgenesis and CRISPR Genome Editing. (2021) (4)
Heterozygous mutation to Chd8 causes macrocephaly and widespread alteration of neurodevelopmental transcriptional networks in mouse (2016) (4)
Author Correction: An atlas of dynamic chromatin landscapes in mouse fetal development (2020) (3)
HAND transcription factors cooperatively specify the aorta and pulmonary trunk. (2021) (3)
Apolipoprotein A5: A newly identified gene impacting plasmatriglyceride levels in humans and mice (2002) (3)
Apolipoprotein A 5 , a Crucial Determinant of Plasma Triglyceride Levels , is Highly Responsive to PPAR α Activators (2003) (3)
APOLIPOPROTEIN AIV GENE VARIANT S 347 IS ASSOCIATED WITH INCREASED RISK OF CORONARY HEART DISEASE AND LOWER APOLIPOPROTEIN AIV PLASMA CONCENTRATIONS Submission Type : Original Contribution (2002) (3)
Comparative and functional analysis of cardiovascular-related genes. (2003) (3)
Human genome meeting 2016 (2016) (3)
Author Correction: An atlas of dynamic chromatin landscapes in mouse fetal development (2021) (3)
Single nucleus analysis of the chromatin landscape in mouse forebrain development (2017) (3)
Differential Etv2 threshold requirement for endothelial and erythropoietic development (2022) (2)
Response to Wang et al. (2005) (2)
BAF chromatin remodeling complex subunit diversity promotes temporally distinct gene expression programs in cardiogenesis (2017) (2)
Uncovering Hidden Enhancers Through Unbiased In Vivo Testing (2022) (2)
Hess from Cow Rumen Metagenomic Discovery of Biomass-Degrading Genes and Genomes (2012) (2)
De Novo Mutation in an Enhancer of EBF3 in simplex autism (2020) (2)
Author Correction: Expanded encyclopaedias of DNA elements in the human and mouse genomes (2022) (2)
Single cell, whole embryo phenotyping of pleiotropic disorders of mammalian development (2022) (2)
An apolipoprotein identified through comparative sequence analysis influences triglyceride levels in humans and mice. (2001) (2)
Deletion of a non-canonical regulatory sequence causes loss of Scn1a expression and epileptic phenotypes in mice (2021) (1)
Noncoding deletions reveal a gene that is critical for intestinal function (2019) (1)
Apolipoprotein A5: A newly identified gene impacting plasma triglyceride levels in humans and mice - eScholarship (2002) (1)
Isolation, characterization, and genome sequence of the first representative of a novel class within the Chloroflexi that is abundant in some U.S. Great Basin hot springs and may play important roles in N and C cycling (2011) (1)
Apolipoprotein A 5 : A Newly Identified Gene Impacting Plasma Triglyceride Levels in Humans and Mice (2002) (1)
Apolipoprotein AIF gene variant S347 is associated with increased risk of coronary heart disease and lower apolipoprotein AIV plasma concent rations (2003) (1)
Author Correction: Single-nucleus analysis of accessible chromatin in developing mouse forebrain reveals cell-type-specific transcriptional regulation (2017) (1)
- 1-Enhancer Identification through Comparative Genomics (2006) (1)
Phosphorylation-dependent down-regulation of apolipoprotein A5 by insulin (2004) (1)
A gene desert required for regulatory control of pleiotropic Shox2 expression and embryonic survival (2020) (1)
Ultraconserved Enhancers Are Required for Normal Development Graphical Abstract Highlights (2018) (1)
Improvements to the Illumina Sequencing System and New Applications (2009) (0)
Directed Evolution of Ionizing Radiation 2 Resistance in Escherichia coli 3 4 5 (2009) (0)
Heterozygous mutation to Chd 8 causes macrocephaly and widespread 1 alteration of neurodevelopmental transcriptional networks in mouse 2 3 (2016) (0)
Resequencing: The Untold Story - Recognizing False Positives, False Negatives and Structural Variation in User Data (2012) (0)
Gap Closing/Finishing by Targeted Genomic Region Enrichment and Sequencing (2010) (0)
Author Correction: Expanded encyclopaedias of DNA elements in the human and mouse genomes (2022) (0)
Differences in enhancer activity in mouse and zebrafish reporter assays are often associated with changes in gene expression (2012) (0)
Lawrence Berkeley National Laboratory Lawrence Berkeley National Laboratory Title Medical Sequencing at the extremes of Human Body Mass Permalink (0)
Assessment, optimization and Applications of 454 FLX Titanium Sequencing Systems (2009) (0)
Barcode labeling of short reads for detection of large scale genomic variations (2012) (0)
Large-scale identification of tissue-specific enhancers in vivo (2010) (0)
Most of rare missense alleles in humans are deleterious: implications for evolution of complex disease and association studies (2006) (0)
Integrative analysis of the 3D genome and epigenome in mouse embryonic tissues (2022) (0)
An atlas of dynamic chromatin landscapes in mouse fetal development (2020) (0)
Linkage and association of haplotypes at the APOA1/C3/A4/A5 gene cluster to familial combined hyperlipidemia - eScholarship (2002) (0)
Dysregulated RAS signalling in Noonan syndrome and related disorders: disease gene discovery and functional studies (2010) (0)
Perfect and imperfect views of ultraconserved sequences (2021) (0)
ATVB In Focus Lipoproteins, Inflammation, and Atherosclerosis (2003) (0)
Author response: A Cryptochrome 2 mutation yields advanced sleep phase in humans (2016) (0)
SNP-VISTA: An interactive SNP visualization tool - eScholarship (2005) (0)
Fosmid Ditags as a New Technology Developed at JGI (2007) (0)
Lawrence Berkeley National Laboratory Lawrence Berkeley National Laboratory Title Lack of Support for the Association Between GAD 2 Polymorphisms and Severe Human Obesity Permalink (2005) (0)
Linkage and association of haplotypes at the APOA1/C3/A4/A5 gene cluster to familial combined hyperlipidemia (2002) (0)
Author Correction: Perspectives on ENCODE (2022) (0)
Independent effects of apolipoprotein AV and apolipoprotein CIII on plasma triglyceride concentrations (2003) (0)
ChIP-seq Mapping of Distant-Acting Enhancers and Their In Vivo Activities (2011) (0)
PacBio Only Assembly with Low Genomic DNA Input (2013) (0)
W13.325 Apolipoprotein A-V accelerates catabolism of triglyceride-rich lipoproteins in vivo (2004) (0)
Activating mutations in SOS1 cause a distinctive form of Noonan syndrome (2007) (0)
Author Correction: Expanded encyclopaedias of DNA elements in the human and mouse genomes (2022) (0)
3P-0834 Transcriptional regulation of the apolipoprotein A5 gene by insulin (2003) (0)
High throughput sequencing recovers the novel gene Megf8 as the ENU induced mutation causing single ventricle cardiac defect associated with randomized left-right patterning (2008) (0)
Their Remnants Attributable to Decreased Lipolysis of Triglyceride-Rich Lipoproteins and Apolipoprotein AV Deficiency Results in Marked Hypertriglyceridemia (2005) (0)
Single cell evaluation of endocardial HAND2 gene regulatory networks reveals critical HAND2 dependent pathways impacting cardiac morphogenesis (2022) (0)
provides a high-throughput alternative to in vivo enhancer analyses Single site-specific integration targeting coupled with embryonic stem cell differentiation (2015) (0)
Lawrence Berkeley National Laboratory Recent Work Title Dynamic GATA 4 enhancers shape the chromatin landscape central to heart development and disease (2016) (0)
Occupancy by key transcription factors is a more accurate predictor of enhancer activity than histone modifications or chromatin accessibility (2015) (0)
Exploring Variation Detection Within a Wide Range of Bioenergy-Relevant Species Via Short Read Technology (2009) (0)
Author Correction: Single-nucleus analysis of accessible chromatin in developing mouse forebrain reveals cell-type-specific transcriptional regulation (2018) (0)
Genetic determinants of switchgrass-root-associated microbiota in field sites spanning its natural range (2023) (0)
Linkage and Association of Haplotypes at the APOA 1 / C 3 / A 4 / A 5 Gene Cluster to Familial Combined Hyperlipidemia (2002) (0)
Software SNP-VISTA: An interactive SNP visualization tool (2006) (0)
Identification and characterization of novel Fgf17 enhancers active in the rostral forebrain signaling center (2008) (0)
The genome and the evolution of the chordate karyotype (2008) (0)
Lawrence Berkeley National Laboratory Recent Work Title Relationship between genetic variation at PPP 1 R 3 B and levels of liver glycogen and triglyceride Permalink (2018) (0)
Phasing Variants in Poplar Trees using a Hybrid of Short & Long Read Technologies (2013) (0)
Linkage and association of haplotypes at the APOA1/C3/A4/A5 genecluster to familial combined hyperlipidemia (2002) (0)
Heritability and host genomic determinants of switchgrass root-associated microbiota in field sites spanning its natural range (2022) (0)
Topologically associating domain boundaries are required for normal genome function (2023) (0)
Coding and noncoding variants in EBF3 are involved in HADDS and simplex autism (2021) (0)
DOE Contribution to Sequencing the Human Genome (2004) (0)
Stable enhancers are active in development, and fragile enhancers are associated with evolutionary adaptation (2019) (0)
Tissue-Specific Enhancers in the Human Genome (2006) (0)

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What Schools Are Affiliated With Len A. Pennacchio?

Len A. Pennacchio is affiliated with the following schools: