Leonard Lerman

Q: What Schools Are Affiliated With Leonard Lerman

Leonard Lerman is affiliated with the following schools: University of California, Berkeley, California Institute of Technology, Vanderbilt University, Massachusetts Institute of Technology, University of Chicago, University of Colorado, California State University, East Bay

Leonard Lerman's AcademicInfluence.com Rankings

Leonard Lerman

Chemistry

#1154

World Rank

#1815

Historical Rank

#463

USA Rank

chemistry Degrees

Leonard Lerman

Biology

#1150

World Rank

#1960

Historical Rank

#595

USA Rank

Biochemistry

#582

World Rank

#672

Historical Rank

#196

USA Rank

biology Degrees

Download Badge

Chemistry
Biology

Leonard Lerman's Degrees

PhD Chemistry University of California, Berkeley
Bachelors Chemistry University of California, Berkeley

Why Is Leonard Lerman Influential?

(Suggest an Edit or Addition)

According to Wikipedia, Leonard Solomon Lerman was an American scientist most noted for his work on DNA. Life and career Lerman was born and raised in Pittsburgh, the son of Freamah and Meyer Lerman, Jewish immigrants from Ukraine. His father was a department store buyer. Lerman began attending the Carnegie Institute of Technology before graduating from high school and received his BS in five semesters. As a graduate student with Linus Pauling at the California Institute of Technology, Lerman discovered that antibodies have two binding sites. Later, perhaps his most important discovery was that certain molecules bind to DNA by intercalation. This discovery has shaped much of science's understanding about how drugs and mutagens interact with DNA.

(See a Problem?)

Leonard Lerman's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Structural considerations in the interaction of DNA and acridines. (1961) (1936)
Attachment of a 40-base-pair G + C-rich sequence (GC-clamp) to genomic DNA fragments by the polymerase chain reaction results in improved detection of single-base changes. (1989) (1346)
Detection and localization of single base changes by denaturing gradient gel electrophoresis. (1987) (957)
DNA fragments differing by single base-pair substitutions are separated in denaturing gradient gels: correspondence with melting theory. (1983) (881)
Nearly all single base substitutions in DNA fragments joined to a GC-clamp can be detected by denaturing gradient gel electrophoresis. (1985) (633)
The structure of the DNA-acridine complex. (1963) (623)
Computational simulation of DNA melting and its application to denaturing gradient gel electrophoresis. (1987) (495)
Detection of single base substitutions in total genomic DNA (1985) (359)
Length-independent separation of DNA restriction fragments in two-dimensional gel electrophoresis (1979) (351)
ACRIDINE MUTAGENS AND DNA STRUCTURE. (1964) (347)
A transition to a compact form of DNA in polymer solutions. (1971) (300)
Why does the electrophoretic mobility of DNA in gels vary with the length of the molecule? (1982) (296)
Modification of the melting properties of duplex DNA by attachment of a GC-rich DNA sequence as determined by denaturing gradient gel electrophoresis. (1985) (260)
A general method for saturation mutagenesis of cloned DNA fragments. (1985) (243)
Immunologic Adsorbents: I. Isolation of Antibody by Means of a Cellulose-Protein Antigen. (1951) (205)
Sequence-determined DNA separations. (1984) (188)
Interaction of DNA and proflavine: a small-angle x-ray scattering study. (1961) (158)
The structure of ψ DNA (1974) (154)
Genetic transformation. I. Cellular incorporation of DNA accompanying transformation in Pneumococcus. (1957) (145)
Comprehensive detection of single base changes in human genomic DNA using denaturing gradient gel electrophoresis and a GC clamp. (1990) (125)
Separation of random fragments of DNA according to properties of their sequences. (1980) (124)
Genetic transformation. II. The significance of damage to the DNA molecule. (1959) (113)
AMINO GROUP REACTIVITY IN DNA--AMINOACRIDINE COMPLEXES. (1964) (105)
Thermodynamics and equilibrium sedimentation analysis of the close approach of DNA molecules and a molecular ordering transition (1981) (88)
A genetic analysis by transformation of a group of uracil-requiring mutants of Diplococcus pneumoniae. (1969) (74)
A Biochemically Specific Method for Enzyme Isolation. (1953) (67)
Kinetics and intermediates in the intracellular synthesis of bacteriophage T4 deoxyribonucleic acid. (1970) (64)
Small RNA. (1983) (55)
Searching for gene defects by denaturing gradient gel electrophoresis. (1986) (54)
A mitochondrial DNA deletion in normally aging and in Alzheimer brain tissue. (1993) (50)
Analysis of double-helix motions with spin-labeled probes: binding geometry and the limit of torsional elasticity. (1980) (49)
Antibody Chromatography on an Immunologically Specific Adsorbent (1953) (44)
Chromatographic fractionation of the transforming principle of the pneumococcus. (1955) (39)
DNA packing in single crystals inferred from freeze-fracture-etch replicas. (1976) (37)
Comprehensive, rapid and sensitive detection of sequence variants of human mitochondrial tRNA genes. (1997) (36)
Torsional motion and elasticity of the deoxyribonucleic acid double helix and its nucleosomal complexes. (1982) (35)
Two-dimensional electrophoretic separation of restriction enzyme fragments of DNA. (1979) (31)
Preferential isolation of DNA fragments associated with CpG islands. (1995) (27)
Structure and circular dichroism of DNA in concentrated polymer solutions. (1972) (21)
Intramolecular DNA melting between stable helical segments: melting theory and metastable states. (1995) (17)
Effects of 9-aminoacridine on bacteriophage T4 deoxyribonucleic acid synthesis. (1970) (16)
Scaling of the equilibrium sedimentation distribution in dense DNA solutions. (1984) (16)
Hemodynamics of aortic occlusion. (1949) (14)
Intercalability, the ψ Transition, and the State of DNA in Nature (1971) (14)
Dependence of the electrophoretic mobility of DNA in gels on field intermittency. (1985) (13)
Uptake of glycine-I-14C into the actomyosin and collagen fractions of developing chick muscle. (1958) (12)
Comprehensive screening of the human KRAS2 gene for sequence variants (1993) (11)
THE RELIEF OF MYXEDEMA WITH PROTEINS OF EXTRATHYROIDAL ORIGIN (1939) (11)
The structure of psi DNA. (1974) (11)
The effects of lithium, rubidium, cesium and magnesium ions on the close packing of persistence-length DNA fragments. (1991) (10)
DNA mutation detection via fluorescence imaging in a spatial thermal gradient, capillary electrophoresis system (2001) (9)
The isolation of CpG islands from human chromosomal regions 11q13 and Xp22 by segregation of partlymelted molecules. (1998) (8)
The Museum : one hundred years and the Metropolitan Museum of Art (1969) (7)
CHAPTER 19 – The Polymer and Salt-induced Condensation of DNA† (1973) (7)
DNA probes : application in genetic and infectious disease and cancer (1986) (6)
PCR assay for a polymorphic TaqI site in the human K-ras-2 gene on chromosome 12p (KRAS2). (1991) (5)
Report on the Human Genome Initiative (1987) (5)
Relaxation effects in the gel electrophoresis of DNA in intermittent fields (1989) (5)
Electrophoresis of DNA in Denaturing Gradient Gels (1986) (4)
The combination of DNA with polycyclic aromatic hydrocarbons. (1964) (4)
Chromosomal analogues: long-range order in psi-condensed DNA. (1974) (4)
Detecting sequence changes in a gene (1987) (4)
Internal Twisting of Short DNA Segments (1979) (3)
SYMPOSIUM ON MOLECULAR ACTION OF MUTAGENIC AND CARCINOGENIC AGENTS. (1964) (3)
Sequence-Determined DNA Separations (1984) (2)
Alterations of T4 DNA Synthesis in the Presence of 9-Aminoacridine* (1968) (1)
SEQUENCE-DETERMI NED (1984) (0)
Structural Considerations in the Interaction of DNA and Acridines (1989) (0)
Letter from Leonard S. Lerman to Francis Crick (1964) (0)
1964 Gordon Research Conference on Nucleic Acids (2008) (0)
Segregation of partly melted molecules and its application to the isolation of methylated CpG islands in human cancer cells (2004) (0)
Robust detailed mapping of the human genome (1992) (0)
A Transition toa CompactFormofDNA inPolymerSolutions (poly(vinyl pyrrolidinone)/poly(ethylene oxide)/T4 phage/centrifugation) (1971) (0)
The lytic action of human sera on ehrlich ascites tumor cells in vitro. Abstr. (1961) (0)
[Cloning-idependent mapping technology for genomic fidelity, contig linking, C-DNA site analysis, and gene detection]. Final report (1994) (0)
Stability Analysis for Reactors from Chemical Industry (2003) (0)
Recombinant DNA. (1976) (0)

This paper list is powered by the following services:

Other Resources About Leonard Lerman

en.wikipedia.org

What Schools Are Affiliated With Leonard Lerman?

Leonard Lerman is affiliated with the following schools:

Leonard Lerman's Academic­Influence.com Rankings

Leonard Lerman's Degrees

Why Is Leonard Lerman Influential?

Leonard Lerman's Published Works

Published Works

Other Resources About Leonard Lerman

What Schools Are Affiliated With Leonard Lerman?

Leonard Lerman's AcademicInfluence.com Rankings