Leonard I. Zon
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Biology Philosophy
Leonard I. Zon's Degrees
- Masters Medicine Harvard University
Why Is Leonard I. Zon Influential?
(Suggest an Edit or Addition)According to Wikipedia, Leonard I. Zon, M.D., is the Grousbeck Professor of Pediatric Medicine at Harvard Medical School, Investigator at Howard Hughes Medical Institute, and Director of the Stem Cell Program, Children’s Hospital Boston.
Leonard I. Zon's Published Works
Published Works
- The zebrafish reference genome sequence and its relationship to the human genome (2013) (3401)
- Hematopoiesis: An Evolving Paradigm for Stem Cell Biology (2008) (2288)
- Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis (1996) (1847)
- Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter (2000) (1580)
- In vivo drug discovery in the zebrafish (2005) (1285)
- Transparent adult zebrafish as a tool for in vivo transplantation analysis. (2008) (1135)
- Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis (2007) (1084)
- The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis. (2005) (1027)
- Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun (1994) (1016)
- Cell stem cell. (2007) (918)
- Cloning of cDNA for the major DNA-binding protein of the erythroid lineage through expression in mammalian cells (1989) (818)
- Transplantation and in vivo imaging of multilineage engraftment in zebrafish bloodless mutants (2003) (746)
- Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1 (1994) (740)
- The Wnt/β-Catenin Pathway Is Required for the Development of Leukemia Stem Cells in AML (2010) (732)
- Loss of 5-Hydroxymethylcytosine Is an Epigenetic Hallmark of Melanoma (2012) (699)
- Zebrafish: a model system for the study of human disease. (2000) (671)
- Genetic Interaction of PGE2 and Wnt Signaling Regulates Developmental Specification of Stem Cells and Regeneration (2009) (671)
- BRAF Mutations Are Sufficient to Promote Nevi Formation and Cooperate with p53 in the Genesis of Melanoma (2005) (651)
- Intraembryonic hematopoietic cell migration during vertebrate development. (1995) (621)
- Cloche, an early acting zebrafish gene, is required by both the endothelial and hematopoietic lineages. (1995) (579)
- tp53 mutant zebrafish develop malignant peripheral nerve sheath tumors. (2005) (576)
- The use of zebrafish to understand immunity. (2004) (572)
- Vertebrate genome evolution and the zebrafish gene map (1998) (563)
- The cloche and spadetail genes differentially affect hematopoiesis and vasculogenesis. (1998) (534)
- The molecular nature of zebrafish swirl: BMP2 function is essential during early dorsoventral patterning. (1997) (530)
- Mitoferrin is essential for erythroid iron assimilation (2006) (528)
- Myc-Induced T Cell Leukemia in Transgenic Zebrafish (2003) (524)
- Vertebrate genome evolution and the zebrafish gene map (1998) (513)
- Genetic analysis of cavefish reveals molecular convergence in the evolution of albinism (2006) (487)
- The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset (2011) (471)
- Expression of an erythroid transcription factor in megakaryocytic and mast cell lineages (1990) (467)
- The stress-activated protein kinase pathway mediates cell death following injury induced by cis-platinum, UV irradiation or heat (1996) (458)
- The art and design of genetic screens: zebrafish (2001) (446)
- Hematopoietic stem cell fate is established by the Notch-Runx pathway. (2005) (437)
- Myelopoiesis in the zebrafish, Danio rerio. (2001) (435)
- The ‘definitive’ (and ‘primitive’) guide to zebrafish hematopoiesis (2004) (422)
- Hepatic maturation in differentiating embryonic stem cells in vitro (2001) (421)
- DHODH modulates transcriptional elongation in the neural crest and melanoma (2011) (410)
- Hooked! Modeling human disease in zebrafish. (2012) (402)
- Hematopoietic Stem Cell Development Is Dependent on Blood Flow (2009) (399)
- A comparison of non-integrating reprogramming methods (2014) (397)
- Generation of vascular endothelial and smooth muscle cells from human pluripotent stem cells (2015) (395)
- SUMO-1 modification represses Sp3 transcriptional activation and modulates its subnuclear localization. (2002) (391)
- In vivo tracking of T cell development, ablation, and engraftment in transgenic zebrafish. (2004) (383)
- Deficiency of glutaredoxin 5 reveals Fe–S clusters are required for vertebrate haem synthesis (2005) (369)
- SCL/Tal-1 transcription factor acts downstream of cloche to specify hematopoietic and vascular progenitors in zebrafish. (1998) (365)
- Ubiquitous transgene expression and Cre-based recombination driven by the ubiquitin promoter in zebrafish (2011) (363)
- Signal Transduction Pathways Regulated by Mitogen-activated/Extracellular Response Kinase Kinase Kinase Induce Cell Death (*) (1996) (363)
- Analysis of thrombocyte development in CD41-GFP transgenic zebrafish. (2005) (354)
- An orthologue of the kit-related gene fms is required for development of neural crest-derived xanthophores and a subpopulation of adult melanocytes in the zebrafish, Danio rerio. (2000) (353)
- Zebrafish as a cancer model system. (2002) (350)
- Haematologic manifestations of the human immune deficiency virus (HIV) (1987) (349)
- Zebrafish cancer: the state of the art and the path forward (2013) (340)
- A CRISPR/Cas9 vector system for tissue-specific gene disruption in zebrafish. (2015) (331)
- Effects of RAS on the genesis of embryonal rhabdomyosarcoma. (2007) (319)
- Radiation hybrid mapping of the zebrafish genome. (1999) (307)
- A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation (2016) (297)
- Lineage Regulators Direct BMP and Wnt Pathways to Cell-Specific Programs during Differentiation and Regeneration (2011) (292)
- Prostaglandin-modulated umbilical cord blood hematopoietic stem cell transplantation. (2013) (291)
- Intrinsic and extrinsic control of haematopoietic stem-cell self-renewal (2008) (283)
- Hematopoietic Stem Cell Arrival Triggers Dynamic Remodeling of the Perivascular Niche (2015) (282)
- Hematopoiesis and stem cells: plasticity versus developmental heterogeneity (2002) (279)
- Cancer genetics and drug discovery in the zebrafish (2003) (278)
- The cytoplasmic region of the erythropoietin receptor contains nonoverlapping positive and negative growth-regulatory domains (1991) (276)
- cdx4 mutants fail to specify blood progenitors and can be rescued by multiple hox genes (2003) (272)
- The zebrafish as a model organism to study development of the immune system. (2003) (267)
- Use of the zebrafish system to study primitive and definitive hematopoiesis. (2005) (266)
- Prostaglandin E2 enhances human cord blood stem cell xenotransplants and shows long-term safety in preclinical nonhuman primate transplant models. (2011) (266)
- Loci associated with skin pigmentation identified in African populations (2017) (253)
- GATA-4 is a novel transcription factor expressed in endocardium of the developing heart. (1993) (251)
- Loss of gata1 but not gata2 converts erythropoiesis to myelopoiesis in zebrafish embryos. (2005) (247)
- Induction of multipotential hematopoietic progenitors from human pluripotent stem cells via respecification of lineage-restricted precursors. (2013) (246)
- Positional cloning of the zebrafish sauternes gene: a model for congenital sideroblastic anaemia (1998) (241)
- Tumor-Derived Extracellular Vesicles Breach the Intact Blood Brain Barrier via Transcytosis. (2019) (233)
- Developmental biology of hematopoiesis. (1995) (233)
- Organogenesis--Heart and Blood Formation from the Zebrafish Point of View (2002) (229)
- Activation of the SAPK pathway by the human STE20 homologue germinal centre kinase (1995) (226)
- Direct recruitment of polycomb repressive complex 1 to chromatin by core binding transcription factors. (2012) (223)
- Use of Zebrafish in Drug Discovery Toxicology. (2020) (221)
- SEK1 deficiency reveals mitogen-activated protein kinase cascade crossregulation and leads to abnormal hepatogenesis. (1998) (220)
- Induction of cyclin D1 by simian virus 40 small tumor antigen. (1996) (219)
- Activation of the erythropoietin receptor promoter by transcription factor GATA-1. (1991) (218)
- Zebrafish SPI-1 (PU.1) marks a site of myeloid development independent of primitive erythropoiesis: implications for axial patterning. (2002) (218)
- Suppression of in vitro haematopoiesis following human immunodeficiency virus infection (1987) (218)
- Neuropilin-1 is required for vascular development and is a mediator of VEGF-dependent angiogenesis in zebrafish (2002) (218)
- BMP and Wnt specify hematopoietic fate by activation of the Cdx-Hox pathway. (2008) (218)
- The zebrafish van gogh mutation disrupts tbx1, which is involved in the DiGeorge deletion syndrome in humans (2003) (211)
- The role of BMP-4 and GATA-2 in the induction and differentiation of hematopoietic mesoderm in Xenopus laevis. (1996) (208)
- Mutation in the transcriptional coactivator EYA4 causes dilated cardiomyopathy and sensorineural hearing loss (2005) (207)
- Protein-Damaging Stresses Activate c-Jun N-Terminal Kinase via Inhibition of Its Dephosphorylation: a Novel Pathway Controlled by HSP72 (1999) (200)
- Loss-of-function mutations in the C9ORF72 mouse ortholog cause fatal autoimmune disease (2016) (200)
- An Mll-Dependent Hox Program Drives Hematopoietic Progenitor Expansion (2004) (197)
- Specification of hematopoietic and vascular development by the bHLH transcription factor SCL without direct DNA binding. (1999) (196)
- Cdc42Hs, but Not Rac1, Inhibits Serum-stimulated Cell Cycle Progression at G1/S through a Mechanism Requiring p38/RK* (1997) (194)
- Ontogeny of hematopoiesis: examining the emergence of hematopoietic cells in the vertebrate embryo. (2003) (190)
- APC mutant zebrafish uncover a changing temporal requirement for wnt signaling in liver development. (2008) (189)
- Dynamic Control of Enhancer Repertoires Drives Lineage and Stage-Specific Transcription during Hematopoiesis. (2016) (184)
- Notch and MAML Signaling Drives Scl-Dependent Interneuron Diversity in the Spinal Cord (2007) (183)
- TIF1γ Controls Erythroid Cell Fate by Regulating Transcription Elongation (2010) (182)
- Pathophysiology and management of HIV-associated hematologic disorders. (1989) (181)
- SUMO-1 protease-1 regulates gene transcription through PML. (2002) (179)
- MST/MLK2, a Member of the Mixed Lineage Kinase Family, Directly Phosphorylates and Activates SEK1, an Activator of c-Jun N-terminal Kinase/Stress-activated Protein Kinase* (1997) (178)
- The transcriptional landscape of hematopoietic stem cell ontogeny. (2012) (178)
- Thrombopoietin rescues in vitro erythroid colony formation from mouse embryos lacking the erythropoietin receptor. (1996) (176)
- GATA-binding transcription factors in mast cells regulate the promoter of the mast cell carboxypeptidase A gene. (1991) (176)
- Hematopoietic development in the zebrafish. (2010) (175)
- Expression of GATA-binding proteins during embryonic development in Xenopus laevis. (1991) (173)
- Effects of lethal irradiation in zebrafish and rescue by hematopoietic cell transplantation. (2004) (172)
- Hematologic manifestations of the human immune deficiency virus (HIV). (1988) (172)
- Heat shock-inducible Cre/Lox approaches to induce diverse types of tumors and hyperplasia in transgenic zebrafish (2007) (171)
- A zebrafish bmyb mutation causes genome instability and increased cancer susceptibility. (2005) (166)
- Teratoma formation assays with human embryonic stem cells: a rationale for one type of human-animal chimera. (2007) (165)
- Zebrafish as a model for normal and malignant hematopoiesis (2011) (164)
- Small molecules that delay S phase suppress a zebrafish bmyb mutant (2005) (164)
- The zebrafish: a new model of T-cell and thymic development (2005) (162)
- Characterization of embryonic globin genes of the zebrafish. (2003) (161)
- Dissecting hematopoiesis and disease using the zebrafish. (1999) (161)
- Melanocytes in development and cancer (2010) (160)
- BMP-4-responsive regulation of dorsal–ventral patterning by the homeobox protein Mix.1 (1996) (159)
- Erythropoietin receptor. Subunit structure and activation. (1990) (158)
- Zebrafish blood stem cells (2009) (156)
- A Zebrafish Embryo Culture System Defines Factors that Promote Vertebrate Myogenesis across Species (2013) (155)
- T-lymphoblastic lymphoma cells express high levels of BCL2, S1P1, and ICAM1, leading to a blockade of tumor cell intravasation. (2010) (155)
- The pu.1 promoter drives myeloid gene expression in zebrafish. (2004) (154)
- Cell cycle-dependent initiation and lineage-dependent abrogation of GATA-1 expression in pure differentiating hematopoietic progenitors. (1992) (154)
- Zebrafish: a new model for human disease. (1999) (152)
- Zebrafish scl functions independently in hematopoietic and endothelial development. (2005) (148)
- Chemical genetic screening in the zebrafish embryo (2009) (147)
- Expression of mRNA for the GATA-binding proteins in human eosinophils and basophils: potential role in gene transcription (1993) (145)
- Hematopoietic gene expression profile in zebrafish kidney marrow. (2004) (144)
- PGE2-regulated wnt signaling and N-acetylcysteine are synergistically hepatoprotective in zebrafish acetaminophen injury (2010) (142)
- Fishing for lymphoid genes. (2001) (142)
- Massively parallel reporter assays of melanoma risk variants identify MX2 as a gene promoting melanoma (2020) (140)
- Bipotential primitive-definitive hematopoietic progenitors in the vertebrate embryo. (1997) (138)
- Ventral expression of GATA-1 and GATA-2 in the Xenopus embryo defines induction of hematopoietic mesoderm. (1994) (137)
- Modification of bacterial artificial chromosomes through chi-stimulated homologous recombination and its application in zebrafish transgenesis. (1998) (137)
- A Chemical Genetic Screen for Cell Cycle Inhibitors in Zebrafish Embryos (2006) (137)
- Walking the Walk Migration and Other Common Themes in Blood and Vascular Development (2002) (137)
- The caudal-related homeobox genes cdx1a and cdx4 act redundantly to regulate hox gene expression and the formation of putative hematopoietic stem cells during zebrafish embryogenesis. (2006) (131)
- The major human erythroid DNA-binding protein (GF-1): primary sequence and localization of the gene to the X chromosome. (1990) (131)
- Melanocytes in development, regeneration, and cancer. (2008) (131)
- The Zebrafish moonshine Gene Encodes Transcriptional Intermediary Factor 1γ, an Essential Regulator of Hematopoiesis (2004) (131)
- SCL specifies hematopoietic mesoderm in Xenopus embryos. (1998) (130)
- Isolation and characterization of runxa and runxb, zebrafish members of the runt family of transcriptional regulators. (2002) (130)
- Duplicate VegfA genes and orthologues of the KDR receptor tyrosine kinase family mediate vascular development in the zebrafish. (2007) (128)
- Cell-specific mitotic defect and dyserythropoiesis associated with erythroid band 3 deficiency (2003) (127)
- Small molecule screening in the zebrafish. (2006) (126)
- Oncogenic NRAS cooperates with p53 loss to generate melanoma in zebrafish. (2009) (126)
- Zebrafish stat3 is expressed in restricted tissues during embryogenesis and stat1 rescues cytokine signaling in a STAT1‐deficient human cell line (1999) (126)
- Hematopoiesis (2013) (124)
- High-throughput cell transplantation establishes that tumor-initiating cells are abundant in zebrafish T-cell acute lymphoblastic leukemia. (2010) (124)
- New waves of discovery: modeling cancer in zebrafish. (2007) (122)
- Cooperative effects of growth factors involved in the induction of hematopoietic mesoderm. (1998) (122)
- Characterization of whole genome radiation hybrid mapping resources for non-mammalian vertebrates. (1998) (122)
- Overview of the Zebrafish system. (1999) (120)
- Functional conservation of erythropoietin signaling in zebrafish. (2007) (119)
- Swimming into the future of drug discovery: in vivo chemical screens in zebrafish. (2010) (117)
- Hematopoiesis : a developmental approach (2001) (116)
- Minimum information specification for in situ hybridization and immunohistochemistry experiments (MISFISHIE) (2008) (115)
- The zebrafish klf gene family. (2001) (111)
- Zebrafish globin switching occurs in two developmental stages and is controlled by the LCR. (2012) (111)
- Developmental derivation of embryonic and adult macrophages (2000) (110)
- Mutations in QARS, encoding glutaminyl-tRNA synthetase, cause progressive microcephaly, cerebral-cerebellar atrophy, and intractable seizures. (2014) (107)
- Zebrafish tumor assays: the state of transplantation. (2009) (106)
- A Quantitative System for Studying Metastasis Using Transparent Zebrafish. (2015) (106)
- In vivo immunological function of mast cells derived from embryonic stem cells: an approach for the rapid analysis of even embryonic lethal mutations in adult mice in vivo. (2000) (105)
- The zebrafish mutant gene chardonnay (cdy) encodes divalent metal transporter 1 (DMT1). (2002) (104)
- Zebrafish patient avatars in cancer biology and precision cancer therapy (2020) (101)
- The zebrafish dag1 mutant: a novel genetic model for dystroglycanopathies. (2011) (101)
- The zebrafish spi1 promoter drives myeloid-specific expression in stable transgenic fish. (2003) (101)
- Of fish and men: using zebrafish to fight human diseases. (2013) (101)
- FOG acts as a repressor of red blood cell development in Xenopus. (2000) (101)
- Epoxyeicosatrienoic Acids Enhance Embryonic Haematopoiesis and Adult Marrow Engraftment (2015) (98)
- The dystrophin associated protein complex in zebrafish. (2003) (98)
- Anticardiolipin antibodies associated with HTLV‐III infection (1987) (98)
- Zebrafish disease models in drug discovery: from preclinical modelling to clinical trials (2021) (97)
- Genetics of erythropoiesis: induced mutations in mice and zebrafish. (1997) (97)
- Realizing the potential of zebrafish as a model for human disease. (2000) (97)
- A mutation in separase causes genome instability and increased susceptibility to epithelial cancer. (2007) (97)
- Extensive genetic diversity and substructuring among zebrafish strains revealed through copy number variant analysis (2011) (96)
- Primitive erythropoiesis in the Xenopus embryo: the synergistic role of LMO-2, SCL and GATA-binding proteins. (2001) (95)
- Regulation of the lmo2 promoter during hematopoietic and vascular development in zebrafish. (2005) (95)
- Characterization of Adult α- and β-Globin Genes in the Zebrafish (1997) (94)
- ANTICARDIOLIPIN ANTIBODIES ASSOCIATED WITH HTLV‐III INFECTION (1988) (94)
- A genetic screen in zebrafish defines a hierarchical network of pathways required for hematopoietic stem cell emergence. (2009) (94)
- The zebrafish granulocyte colony-stimulating factors (Gcsfs): 2 paralogous cytokines and their roles in hematopoietic development and maintenance. (2013) (93)
- Selective microRNA uridylation by Zcchc6 (TUT7) and Zcchc11 (TUT4) (2014) (92)
- Targeting the Senescence-Overriding Cooperative Activity of Structurally Unrelated H3K9 Demethylases in Melanoma. (2018) (92)
- The clinical potential of stem cells. (2004) (91)
- Ultrasound biomicroscopy permits in vivo characterization of zebrafish liver tumors (2007) (91)
- Chamber identity programs drive early functional partitioning of the heart (2015) (90)
- Retro-orbital injection in adult zebrafish. (2009) (90)
- PD-L1 genetic overexpression or pharmacological restoration in hematopoietic stem and progenitor cells reverses autoimmune diabetes (2017) (90)
- Gene Duplication of the Zebrafish kit ligand and Partitioning of Melanocyte Development Functions to kit ligand a (2007) (90)
- Antibodies to human T-lymphotropic virus type III (HTLV-III) in saliva of acquired immunodeficiency syndrome (AIDS) patients and in persons at risk for AIDS. (1986) (90)
- Hyperactivation of Sympathetic Nerves Drives Melanocyte Stem Cell Depletion (2019) (89)
- Drug discovery for Diamond-Blackfan anemia using reprogrammed hematopoietic progenitors (2017) (89)
- Nanog-like regulates endoderm formation through the Mxtx2-Nodal pathway. (2012) (89)
- Clonal fate mapping quantifies the number of haematopoietic stem cells that arise during development (2016) (87)
- Structure and transcription of the mouse erythropoietin receptor gene (1990) (87)
- Human tumor genomics and zebrafish modeling identify SPRED1 loss as a driver of mucosal melanoma (2018) (87)
- The Zebra fish cassiopeia Mutant Reveals that SIL Is Required for Mitotic Spindle Organization (2007) (86)
- Zebrafish kidney stromal cell lines support multilineage hematopoiesis. (2009) (86)
- Cdx4 dysregulates Hox gene expression and generates acute myeloid leukemia alone and in cooperation with Meis1a in a murine model (2006) (85)
- Ferroportin1 is required for normal iron cycling in zebrafish. (2005) (85)
- Gene duplication of zebrafish JAK2 homologs is accompanied by divergent embryonic expression patterns: only jak2a is expressed during erythropoiesis. (1999) (84)
- A Network of Epigenetic Regulators Guide Developmental Hematopoiesis In Vivo (2013) (83)
- A Splice Site Mutation in Laminin-α2 Results in a Severe Muscular Dystrophy and Growth Abnormalities in Zebrafish (2012) (83)
- CHMP1A encodes an essential regulator of BMI1-INK4A in cerebellar development (2012) (83)
- Development of T-cells during fish embryogenesis. (1998) (81)
- Hereditary spherocytosis in zebrafish riesling illustrates evolution of erythroid beta-spectrin structure, and function in red cell morphogenesis and membrane stability. (2000) (81)
- Mutant-specific gene programs in the zebrafish. (2005) (80)
- Whole-exome sequencing and functional studies identify RPS29 as a novel gene mutated in multicase Diamond-Blackfan anemia families. (2014) (79)
- The erythropoietin receptor transmembrane region is necessary for activation by the Friend spleen focus-forming virus gp55 glycoprotein (1992) (79)
- Forced GATA-1 expression in the murine myeloid cell line M1: induction of c-Mpl expression and megakaryocytic/erythroid differentiation. (1998) (79)
- Zebrafish VEGF Receptors: A Guideline to Nomenclature (2008) (79)
- Adenosine signaling promotes hematopoietic stem and progenitor cell emergence (2015) (79)
- Chemical screening in zebrafish for novel biological and therapeutic discovery. (2017) (79)
- MED12 Regulates HSC-Specific Enhancers Independently of Mediator Kinase Activity to Control Hematopoiesis. (2016) (79)
- SEK1/MKK4 is required for maintenance of a normal peripheral lymphoid compartment but not for lymphocyte development. (1998) (77)
- Targeted Application of Human Genetic Variation Can Improve Red Blood Cell Production from Stem Cells. (2016) (77)
- Engineering Hematopoietic Stem Cells: Lessons from Development. (2016) (77)
- Transcriptional regulation of hematopoietic stem cell development in zebrafish. (2005) (76)
- AIBP-mediated cholesterol efflux instructs hematopoietic stem and progenitor cell fate (2019) (75)
- The SETDB1 histone methyltransferase is recurrently amplified in and accelerates melanoma (2011) (75)
- The polymerase chain reaction colony miniprep. (1989) (74)
- The LN54 radiation hybrid map of zebrafish expressed sequences. (2001) (74)
- Co-injection strategies to modify radiation sensitivity and tumor initiation in transgenic Zebrafish (2008) (74)
- NOTCH signaling specifies arterial-type definitive hemogenic endothelium from human pluripotent stem cells (2018) (74)
- Expression of mRNA for the GATA-binding proteins in human eosinophils and basophils: potential role in gene transcription. (1993) (73)
- Network of coregulated spliceosome components revealed by zebrafish mutant in recycling factor p110 (2007) (73)
- Inhibition of zebrafish epidermal growth factor receptor activity results in cardiovascular defects (2003) (72)
- Molecular cloning of a cDNA with a novel domain present in the tre-2 oncogene and the yeast cell cycle regulators BUB2 and cdc16. (1995) (72)
- Effects of infectious hematopoietic necrosis virus and infectious pancreatic necrosis virus infection on hematopoietic precursors of the zebrafish. (2000) (71)
- Role of MEKK2-MEK5 in the regulation of TNF-α gene expression and MEKK2-MKK7 in the activation of c-Jun N-terminal kinase in mast cells (2001) (70)
- Intrathymic signals in thymocytes are mediated by p38 mitogen-activated protein kinase. (1996) (68)
- Structure of the mouse Stat 3/5 locus: evolution from Drosophila to zebrafish to mouse. (2001) (68)
- Chemical screening in zebrafish for novel biological and therapeutic discovery. (2011) (67)
- The chianti zebrafish mutant provides a model for erythroid-specific disruption of transferrin receptor 1 (2004) (67)
- Signaling axis involving Hedgehog, Notch, and Scl promotes the embryonic endothelial-to-hematopoietic transition (2012) (66)
- Non-cell autonomous requirement for the bloodless gene in primitive hematopoiesis of zebrafish. (2002) (66)
- Stress from Nucleotide Depletion Activates the Transcriptional Regulator HEXIM1 to Suppress Melanoma. (2016) (65)
- Zebrafish orthologs of human muscular dystrophy genes (2007) (65)
- Estrogen Activation of G-Protein-Coupled Estrogen Receptor 1 Regulates Phosphoinositide 3-Kinase and mTOR Signaling to Promote Liver Growth in Zebrafish and Proliferation of Human Hepatocytes. (2019) (65)
- Novel members of the mitogen-activated protein kinase activator family in Xenopus laevis (1993) (65)
- Site‐directed zebrafish transgenesis into single landing sites with the phiC31 integrase system (2013) (64)
- Molecular association between β-catenin degradation complex and Rac guanine exchange factor DOCK4 is essential for Wnt/β-catenin signaling (2008) (63)
- Analysis of hematopoietic development in the zebrafish. (2005) (63)
- The Chylomicron Count in Diabetes Mellitus (1935) (63)
- The zebrafish : genetics and genomics (1999) (63)
- A novel endothelial-specific heat shock protein HspA12B is required in both zebrafish development and endothelial functions in vitro (2006) (62)
- Zebrafish YAC, BAC, and PAC genomic libraries. (1999) (62)
- Hematopoietic defects in rps29 mutant zebrafish depend upon p53 activation. (2012) (62)
- Portrait of a stem cell. (2002) (62)
- Characterization of zebrafish merlot/chablis as non-mammalian vertebrate models for severe congenital anemia due to protein 4.1 deficiency. (2002) (61)
- Turning mesoderm into blood: the formation of hematopoietic stem cells during embryogenesis. (2000) (61)
- Transferrin-a modulates hepcidin expression in zebrafish embryos. (2009) (61)
- EXTL3 mutations cause skeletal dysplasia, immune deficiency, and developmental delay (2017) (61)
- A G Protein-coupled Receptor from Zebrafish Is Activated by Human Parathyroid Hormone and Not by Human or Teleost Parathyroid Hormone-related Peptide (1999) (60)
- Cloning of Mix-related homeodomain proteins using fast retrieval of gel shift activities, (FROGS), a technique for the isolation of DNA-binding proteins. (1998) (60)
- Intestinal differentiation in zebrafish requires Cdx1b, a functional equivalent of mammalian Cdx2. (2008) (60)
- Small pool expression screening: identification of genes involved in cell cycle control, apoptosis, and early development. (1997) (59)
- SnapShot: Hematopoiesis (2008) (59)
- Clonal analysis of hematopoietic progenitor cells in the zebrafish. (2011) (59)
- Molecular cloning, genetic mapping, and expression analysis of four zebrafish c/ebp genes. (2001) (59)
- Role of interleukin 6 in the growth of myelomaderived cell lines (1992) (59)
- αA-crystallin expression prevents γ-crystallin insolubility and cataract formation in the zebrafish cloche mutant lens (2006) (59)
- The zebrafish runzel muscular dystrophy is linked to the titin gene. (2007) (59)
- Zebrafish models of p53 functions. (2010) (59)
- Newly emerging roles for prostaglandin E2 regulation of hematopoiesis and hematopoietic stem cell engraftment (2010) (58)
- BMP signaling restricts hemato-vascular development from lateral mesoderm during somitogenesis (2006) (58)
- Long-term drug administration in the adult zebrafish using oral gavage for cancer preclinical studies (2016) (57)
- Salivary antibodies as a means of detecting human T cell lymphotropic virus type III/lymphadenopathy-associated virus infection (1986) (56)
- Melanoma biology and the promise of zebrafish. (2008) (56)
- A Critical Role for Calponin 2 in Vascular Development* (2006) (55)
- Getting more for your marrow: boosting hematopoietic stem cell numbers with PGE2. (2014) (55)
- A New System for the Rapid Collection of Large Numbers of Developmentally Staged Zebrafish Embryos (2011) (53)
- The zon laboratory guide to positional cloning in zebrafish. (2011) (53)
- A Non-Canonical Function of Zebrafish Telomerase Reverse Transcriptase Is Required for Developmental Hematopoiesis (2008) (53)
- A Zebrafish Model of Myelodysplastic Syndrome Produced through tet2 Genomic Editing (2014) (53)
- Resolving the controversy about N-cadherin and hematopoietic stem cells. (2010) (52)
- Modeling human hematopoietic and cardiovascular diseases in zebrafish (2003) (52)
- Flow-induced protein kinase A–CREB pathway acts via BMP signaling to promote HSC emergence (2015) (52)
- Insight into GATA1 transcriptional activity through interrogation of cis elements disrupted in human erythroid disorders (2016) (52)
- Reconstitution of novel signalling cascades responding to cellular stresses. (1996) (51)
- A novel chemical screening strategy in zebrafish identifies common pathways in embryogenesis and rhabdomyosarcoma development (2013) (51)
- Inflammasome Regulates Hematopoiesis through Cleavage of the Master Erythroid Transcription Factor GATA1. (2019) (51)
- Advanced zebrafish transgenesis with Tol2 and application for Cre/lox recombination experiments. (2011) (50)
- Generation of a zebrafish P1 artificial chromosome library. (1999) (50)
- A third Ig light chain gene isotype in Xenopus laevis consists of six distinct VL families and is related to mammalian lambda genes. (1996) (49)
- Distinct Roles for Matrix Metalloproteinases 2 and 9 in Embryonic Hematopoietic Stem Cell Emergence, Migration, and Niche Colonization (2017) (49)
- Melanoma models for the next generation of therapies. (2021) (49)
- Evolution of the hypoxia-sensitive cells involved in amniote respiratory reflexes (2017) (49)
- Small molecule screening in zebrafish: swimming in potential drug therapies (2012) (49)
- Modeling Cancer with Flies and Fish. (2019) (48)
- Neural crest development and craniofacial morphogenesis is coordinated by nitric oxide and histone acetylation. (2014) (48)
- Prostaglandin E2: Making More of Your Marrow (2007) (48)
- Notch1 acts via Foxc2 to promote definitive hematopoiesis via effects on hemogenic endothelium. (2015) (47)
- Evolutionary conservation of zebrafish linkage group 14 with frequently deleted regions of human chromosome 5 in myeloid malignancies (2002) (47)
- Zebrafish: a genetic approach in studying hematopoiesis. (2000) (47)
- Cross-species analysis of enhancer logic using deep learning (2020) (46)
- A novel myeloid-restricted zebrafish CCAAT/enhancer-binding protein with a potent transcriptional activation domain. (2001) (46)
- Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis. (2017) (46)
- Protection from UV light is an evolutionarily conserved feature of the hematopoietic niche (2018) (46)
- Definition of the zebrafish genome using flow cytometry and cytogenetic mapping (2007) (46)
- Eya4 regulation of Na+/K+-ATPase is required for sensory system development in zebrafish (2008) (45)
- The genetic heterogeneity and mutational burden of engineered melanomas in zebrafish models (2013) (45)
- Generation and characterization of transgenic zebrafish lines using different ubiquitous promoters (2008) (45)
- Meta-analysis of rare and common exome chip variants identifies S1PR4 and other loci influencing blood cell traits (2016) (45)
- Dissection of vertebrate hematopoiesis using zebrafish thrombopoietin. (2014) (45)
- The zebrafish : biology (1999) (45)
- Characterization of immune-matched hematopoietic transplantation in zebrafish. (2011) (44)
- Slow phosphorylation of a tyrosine residue in LAT optimizes T cell ligand discrimination (2019) (44)
- Abnormal nuclear pore formation triggers apoptosis in the intestinal epithelium of elys-deficient zebrafish. (2009) (44)
- Expression and mapping of duplicate neuropilin-1 and neuropilin-2 genes in developing zebrafish. (2004) (44)
- Zebrafish slc4a2/ae2 anion exchanger: cDNA cloning, mapping, functional characterization, and localization. (2005) (43)
- From fish bowl to bedside: The power of zebrafish to unravel melanoma pathogenesis and discover new therapeutics (2017) (43)
- Stromal cell-derived factor-1 and hematopoietic cell homing in an adult zebrafish model of hematopoietic cell transplantation. (2011) (42)
- neptune, a Krüppel-like transcription factor that participates in primitive erythropoiesis in Xenopus (2001) (41)
- Zebrafish homolog of the leukemia gene CBFB: its expression during embryogenesis and its relationship to scl and gata-1 in hematopoiesis. (2000) (41)
- Tissue Specific Roles for the Ribosome Biogenesis Factor Wdr43 in Zebrafish Development (2014) (41)
- Fish to Learn: Insights into Blood Development and Blood Disorders from Zebrafish Hematopoiesis. (2016) (40)
- Resistance to inflammation underlies enhanced fitness in clonal hematopoiesis (2021) (40)
- Genetic backgrounds and some standard stocks and strains used in zebrafish developmental biology and genetics. (1999) (40)
- CXCR1 remodels the vascular niche to promote hematopoietic stem and progenitor cell engraftment (2017) (40)
- Interaction of retinoic acid and scl controls primitive blood development. (2010) (40)
- DNA methyltransferase 1 functions through C/ebpa to maintain hematopoietic stem and progenitor cells in zebrafish (2015) (39)
- The effect of a depth gradient on the mating behavior, oviposition site preference, and embryo production in the zebrafish, Danio rerio. (2008) (39)
- The Complex Cartography of Stem Cell Commitment (2005) (39)
- Zebrafish blastomere screen identifies retinoic acid suppression of MYB in adenoid cystic carcinoma (2018) (39)
- The Zon laboratory guide to positional cloning in zebrafish. (2004) (39)
- Stimulation of the P-450 side chain cleavage enzyme (CYP11A1) promoter through ras- and Ets-2-signaling pathways. (1996) (37)
- Use of the Zebrafish (Danio rerio) to Define Hematopoiesis (1998) (37)
- Blood on the tracks: hematopoietic stem cell-endothelial cell interactions in homing and engraftment (2017) (37)
- The zebrafish : genetics, genomics and informatics (2004) (37)
- Self-renewal versus differentiation, a job for the mighty morphogens (2001) (37)
- Transcriptional regulation of blood formation during Xenopus development. (1998) (36)
- Topoisomerase IIα Is Required for Embryonic Development and Liver Regeneration in Zebrafish (2009) (36)
- TiF1-gamma plays an essential role in murine hematopoiesis and regulates transcriptional elongation of erythroid genes. (2013) (36)
- Endothelium--Chicken Soup for the Endoderm (2001) (36)
- zebraflash transgenic lines for in vivo bioluminescence imaging of stem cells and regeneration in adult zebrafish (2013) (36)
- Role of interleukin 6 in the growth of myeloma-derived cell lines. (1992) (36)
- Characterization of adult alpha- and beta-globin genes in the zebrafish. (1997) (35)
- Molecular cloning and developmental expression of Tlx (Hox11) genes in zebrafish (Danio rerio) (2002) (35)
- A chemical genetic screen in zebrafish for pathways interacting with cdx4 in primitive hematopoiesis. (2010) (35)
- Teleost growth factor independence (gfi) genes differentially regulate successive waves of hematopoiesis. (2013) (34)
- montalcino, A zebrafish model for variegate porphyria. (2008) (34)
- Taking human cancer genes to the fish: a transgenic model of melanoma in zebrafish. (2005) (34)
- Zebrafish rhabdomyosarcoma reflects the developmental stage of oncogene expression during myogenesis (2013) (33)
- The new age of chemical screening in zebrafish. (2010) (33)
- Genetic regulation of delta-aminolevulinate dehydratase during erythropoiesis (1996) (32)
- cpsf1 is required for definitive HSC survival in zebrafish. (2011) (32)
- The zebrafish : cellular and developmental biology (2004) (32)
- Mitochondrial function in development and disease (2021) (32)
- c-myb hyperactivity leads to myeloid and lymphoid malignancies in zebrafish (2017) (32)
- Cancer immunotherapy: The dark side of PD-1 receptor inhibition (2017) (32)
- Zebrafish KLF4 is essential for anterior mesendoderm/pre‐polster differentiation and hatching (2005) (31)
- CAT7 and cat7l Long Non-coding RNAs Tune Polycomb Repressive Complex 1 Function during Human and Zebrafish Development * (2016) (31)
- A non-canonical function of telomerase RNA in the regulation of developmental myelopoiesis in zebrafish (2014) (31)
- RNA helicase DDX21 mediates nucleotide stress responses in neural crest and melanoma cells (2020) (31)
- Intrinsic expression of a multiexon type 3 deiodinase gene controls zebrafish embryo size. (2014) (31)
- A Cdx4-Sall4 Regulatory Module Controls the Transition from Mesoderm Formation to Embryonic Hematopoiesis (2013) (30)
- Formation of a PKCζ/β-catenin complex in endothelial cells promotes angiopoietin-1-induced collective directional migration and angiogenic sprouting. (2012) (30)
- Specific oxylipins enhance vertebrate hematopoiesis via the receptor GPR132 (2018) (30)
- The Histone Methyltransferase SUV39H1 Suppresses Embryonal Rhabdomyosarcoma Formation in Zebrafish (2013) (30)
- Mutation of kri1l causes definitive hematopoiesis failure via PERK-dependent excessive autophagy induction (2015) (30)
- Zebrafish mutants with disrupted early T‐cell and thymus development identified in early pressure screen (2008) (30)
- Assaying hematopoiesis using zebrafish. (2013) (30)
- Modeling Diamond Blackfan anemia in the zebrafish. (2011) (29)
- Understanding the regulation of vertebrate hematopoiesis and blood disorders – big lessons from a small fish (2016) (29)
- Hematopoietic stem cells, hematopoiesis and disease: lessons from the zebrafish model (2011) (29)
- Stem cell safe harbor: the hematopoietic stem cell niche in zebrafish. (2018) (29)
- Combinatorial regulation of novel erythroid gene expression in zebrafish. (2008) (28)
- The Zebrafish as a Model System for the Study of Hematopoiesis (1999) (28)
- Efforts to enhance blood stem cell engraftment: Recent insights from zebrafish hematopoiesis (2017) (28)
- Angiopoietin-like proteins stimulate HSPC development through interaction with notch receptor signaling (2015) (28)
- RNA helicase, DDX27 regulates skeletal muscle growth and regeneration by modulation of translational processes (2018) (28)
- Gain-of-function genetic alterations of G9a drive oncogenesis. (2020) (27)
- Primary fibroblast cell culture. (1999) (27)
- An optical platform for cell tracking in adult zebrafish (2012) (27)
- Zebrafish to humans: evolution of the alpha3-chain of type IV collagen and emergence of the autoimmune epitopes associated with Goodpasture syndrome. (2006) (27)
- FAM210B is an erythropoietin target and regulates erythroid heme synthesis by controlling mitochondrial iron import and ferrochelatase activity (2018) (26)
- Identifying Novel Cancer Therapies Using Chemical Genetics and Zebrafish. (2016) (26)
- Transplantation in zebrafish. (2017) (26)
- Characterization of zebrafish full-length prothrombin cDNA and linkage group mapping. (2000) (25)
- Molecular cloning of a human Vent-like homeobox gene. (2001) (25)
- PRL3-DDX21 Transcriptional Control of Endolysosomal Genes Restricts Melanocyte Stem Cell Differentiation (2020) (24)
- Isolation and characterization of zebrafish NFE2. (2002) (24)
- Zebrafish modeling reveals that SPINT1 regulates the aggressiveness of skin cutaneous melanoma and its crosstalk with tumor immune microenvironment (2019) (24)
- Mapping zebrafish mutations by AFLP. (1999) (24)
- Toddler signaling regulates mesodermal cell migration downstream of Nodal signaling (2016) (24)
- Ex vivo tools for the clonal analysis of zebrafish hematopoiesis (2016) (24)
- Transplantation in zebrafish. (2011) (23)
- Long-Range Optogenetic Control of Axon Guidance Overcomes Developmental Boundaries and Defects. (2020) (22)
- The extinction of erythroid genes after tetradecanoylphorbol acetate treatment of erythroleukemic cells correlates with down-regulation of the tissue-specific factors NF-E1 and NF-E2. (1990) (22)
- Tissue-specific gene targeting using CRISPR/Cas9. (2016) (22)
- Concentration-dependent positive and negative regulation of a MAP kinase by a MAP kinase kinase (1999) (22)
- Isolation of a novel receptor tyrosine kinase cDNA expressed by developing erythroid progenitors. (1993) (22)
- Novel cardiovascular gene functions revealed via systematic phenotype prediction in zebrafish (2014) (21)
- Treatment of psoriasis with massive doses of crystalline vitamin D and irradiated ergosterol, A preliminary report. (1937) (21)
- Ccdc94 Protects Cells from Ionizing Radiation by Inhibiting the Expression of p53 (2012) (21)
- A chemical screen in zebrafish embryonic cells establishes that Akt activation is required for neural crest development (2017) (21)
- Construction and application of a zebrafish array comparative genomic hybridization platform (2009) (20)
- Small molecule screen in zebrafish and HSC expansion. (2010) (20)
- TopBP1 Governs Hematopoietic Stem/Progenitor Cells Survival in Zebrafish Definitive Hematopoiesis (2015) (20)
- APC and colon cancer: two hits for one (2007) (20)
- Corrigendum: The zebrafish reference genome sequence and its relationship to the human genome (2013) (20)
- Essential Zebrafish Methods : Cell and Developmental Biology (2009) (20)
- Generation of mouse-zebrafish hematopoietic tissue chimeric embryos for hematopoiesis and host-pathogen interaction studies (2017) (20)
- Hematopoietic stem cells develop in the absence of endothelial cadherin 5 expression. (2015) (19)
- Regulation of stem cells in the zebra fish hematopoietic system. (2008) (19)
- The zebrafish : disease models and chemical screens (2011) (19)
- Molecular insights into early hematopoiesis (1998) (19)
- Homing sweet homing: odyssey of hematopoietic stem cells. (2006) (19)
- Cdx4 is dispensable for murine adult hematopoietic stem cells but promotes MLL-AF9-mediated leukemogenesis (2010) (19)
- The Presence of Histamine in the Platelets of the Rabbit (1939) (19)
- Sequence of the human GATA-1 promoter. (1992) (19)
- Stem cells: The right neighbour (2012) (18)
- Neural crest state activation in NRAS driven melanoma, but not in NRAS-driven melanocyte expansion. (2019) (18)
- Cell-specific transcriptional control of mitochondrial metabolism by TIF1γ drives erythropoiesis (2021) (18)
- Evolutionarily conserved alternative pre-mRNA splicing regulates structure and function of the spectrin-actin binding domain of erythroid protein 4.1. (1995) (17)
- Two distinct teleost hepatocyte nuclear factor 1 genes, hnf1alpha/tcf1 and hnf1beta/tcf2, abundantly expressed in liver, pancreas, gut and kidney of zebrafish. (2004) (17)
- Calmodulin inhibitors improve erythropoiesis in Diamond-Blackfan anemia (2020) (17)
- Gene mapping in zebrafish using single-strand conformation polymorphism analysis. (1998) (17)
- NNT mediates redox-dependent pigmentation via a UVB- and MITF-independent mechanism (2021) (17)
- JDP2: An oncogenic bZIP transcription factor in T cell acute lymphoblastic leukemia (2018) (17)
- Making HSCs in vitro: don't forget the hemogenic endothelium. (2018) (17)
- Selective microRNA uridylation by Zcchc 6 ( TUT 7 ) and Zcchc 11 ( TUT 4 ) (2014) (17)
- Histocompatibility and Hematopoietic Transplantation in the Zebrafish (2012) (16)
- ISOLATION AND TRANSCRIPTOME ANALYSIS OF ADULT ZEBRAFISH CELLS ENRICHED FOR SKELETAL MUSCLE PROGENITORS (2011) (16)
- Fishing for answers in precision cancer medicine (2017) (16)
- Phospholipase C gamma-1 is required for granulocyte maturation in zebrafish. (2013) (16)
- Love, Honor, and Protect (Your Liver) (2003) (16)
- Mlck1a is expressed in zebrafish thrombocytes and is an essential component of thrombus formation (2010) (16)
- Vascular and blood gene expression. (1999) (16)
- Erythropoietin in liver tissue extracts and in liver perfusates from hypoxic rats. (1983) (16)
- Lessons from the Niche for Generation and Expansion of Hematopoietic Stem Cells. (2009) (16)
- Transplantation of whole kidney marrow in adult zebrafish. (2007) (16)
- Common variants in signaling transcription-factor-binding sites drive phenotypic variability in red blood cell traits (2020) (15)
- The NOTCH pathway contributes to cell fate decision in myelopoiesis (2011) (15)
- Defining cancer stem cells by xenotransplantation in zebrafish. (2009) (15)
- A phase II trial of all-trans retinoic acid (ATRA) in advanced adenoid cystic carcinoma. (2021) (14)
- Using Zebrafish to Study Pathways that Regulate Hematopoietic Stem Cell Self-Renewal and Migration (2017) (14)
- Cancer and Inflammation: An Aspirin a Day Keeps the Cancer at Bay (2012) (14)
- Targeting the Senescence-Overriding Cooperative Activity of Structurally Unrelated H3K9 Demethylases in Melanoma. (2018) (14)
- KIT Suppresses BRAFV600E-Mutant Melanoma by Attenuating Oncogenic RAS/MAPK Signaling. (2017) (14)
- Rapid amplification of lambda gt11 bacteriophage library inserts from plaques using the polymerase chain reaction (PCR). (1989) (14)
- The zebrafish: cellular and developmental biology, part A. Preface. (2010) (14)
- Stress‐ and mitogen‐activated signal transduction in hematopoietic cells (1996) (14)
- Hematopoietic transcription regulators and the origins of leukemia. (1992) (14)
- A point mutation of zebrafish c-cbl gene in the ring finger domain produces a phenotype mimicking human myeloproliferative disease (2015) (14)
- Fishing at the cellular level (2010) (13)
- High throughput in vivo phenotyping: The zebrafish as tool for drug discovery for hematopoietic stem cells and cancer (2013) (13)
- Erratum: Targeting the Senescence-Overriding Cooperative Activity of Structurally Unrelated H3K9 Demethylases in Melanoma (Cancer Cell (2018) 33(2) (322–336.e8) (S1535610818300023) (10.1016/j.ccell.2018.01.002)) (2018) (13)
- Embryonic cell culture in zebrafish. (2016) (13)
- Epo-EpoR signaling not required for cardiovascular or neural development (2002) (12)
- The gene encoding TBC1D1 with homology to the tre-2/USP6 oncogene, BUB2, and cdc16 maps to mouse chromosome 5 and human chromosome 4 (2000) (12)
- Use of the DsRed fluorescent reporter in zebrafish. (2004) (12)
- Appendix 3 Collection, Storage, and Use of Zebrafish Sperm (1998) (12)
- SPRED1 deletion confers resistance to MAPK inhibition in melanoma (2020) (12)
- Essential zebrafish methods : genetics and genomics (2009) (12)
- Simple sequence-length polymorphism analysis. (1999) (12)
- Use of the zebrafish (danio rerio) to define hematopoiesis (1998) (12)
- In Situ Hybridization Assay‐Based Small‐Molecule Screening in Zebrafish (2012) (11)
- CHD7 and Runx1 interaction provides a braking mechanism for hematopoietic differentiation (2020) (11)
- The Physical Chemistry of Silver Staining (1936) (11)
- Cloning and genetic mapping of zebrafish BMP-2. (1998) (11)
- Hemophilus parainfluenzae prostatitis in a homosexual man with chronic lymphadenopathy syndrome and HTLV-III infection. (1987) (11)
- 9 - The zebrafish as a model for human disease (2010) (11)
- GATA Factor-G-Protein-Coupled Receptor Circuit Suppresses Hematopoiesis (2016) (11)
- Quality assurance of hematopoietic stem cells by macrophages determines stem cell clonality (2022) (10)
- The histone demethylase Jmjd3 regulates zebrafish myeloid development by promoting spi1 expression. (2018) (10)
- Stem cells: The blood balance (2010) (10)
- Protection from UV light is an evolutionarily conserved feature of the haematopoietic niche (2016) (10)
- Generation of Parabiotic Zebrafish Embryos by Surgical Fusion of Developing Blastulae. (2016) (10)
- Generating and evaluating a ranked candidate gene list for potential vertebrate heart field regulators (2015) (10)
- Chromatin immunoprecipitation in adult zebrafish red cells. (2011) (10)
- The Red Light District and Its Effects on Zebrafish Reproduction. (2016) (10)
- pathway Hematopoietic stem cell fate is established by the Notch – Runx data (2005) (9)
- An evolutionary ancient mechanism for regulation of hemoglobin expression in vertebrate red cells. (2020) (9)
- Cloning and chromosomal localization of a mouse cDNA with homology to the Saccharomyces cerevisiae gene zuotin. (1995) (9)
- Identification of Padi2 as a novel angiogenesis-regulating gene by genome association studies in mice (2017) (9)
- Single-cell ATAC-seq reveals GATA2-dependent priming defect in myeloid and a maturation bottleneck in lymphoid lineages. (2021) (9)
- The ERGonomics of hematopoietic stem cell self-renewal. (2011) (9)
- Author Correction: Epoxyeicosatrienoic acids enhance embryonic haematopoiesis and adult marrow engraftment (2019) (9)
- Impact of COVID-19 Pandemic on Cancer Research (2020) (9)
- Nfe2 is dispensable for early but required for adult thrombocyte formation and function in zebrafish. (2016) (8)
- From fish tank to bedside in cancer therapy: an interview with Leonard Zon (2014) (8)
- Transcriptome Dynamics of Hematopoietic Stem Cell Formation Revealed Using a Combinatorial Runx1 and Ly6a Reporter System (2020) (8)
- Sorting zebrafish thrombocyte lineage cells with a Cd41 monoclonal antibody enriches hematopoietic stem cell activity. (2017) (8)
- Genetic Dissection of Hematopoiesis Using the Zebrafish (2006) (8)
- Calmodulin Inhibition Rescues DBA Models with Ribosomal Protein Deficiency through Reduction of RSK Signaling (2016) (8)
- Analysis of the role of MKK-4/Sek-1 in T cell development and apoptosis. (1998) (8)
- The Paf1 complex and P-TEFb have reciprocal and antagonist roles in maintaining multipotent neural crest progenitors (2019) (7)
- Translational research: the path for bringing discovery to patients. (2014) (7)
- Telomerase RNA recruits RNA polymerase II to target gene promoters to enhance myelopoiesis (2021) (7)
- Modeling human diseases: an education in interactions and interdisciplinary approaches (2016) (7)
- SATB2 induction of a neural crest mesenchyme-like program drives melanoma invasion and drug resistance (2021) (7)
- Use of Zebrafish Models for the Analysis of Human Disease (2002) (7)
- Single-cell analyses reveal early thymic progenitors and pre-B cells in zebrafish (2022) (6)
- Cross-species analysis of melanoma enhancer logic using deep learning (2019) (6)
- The gene encoding protein kinase SEK1 maps to mouse chromosome 11 and human chromosome 17. (1996) (6)
- Collection, storage, and use of zebrafish sperm. (1999) (6)
- Linking hematopoietic regeneration to developmental signaling pathways (2012) (6)
- Prostaglandin E 2 enhances engraftment of human cord blood stem cells and shows long-term safety in preclinical non-human primate transplant models (2017) (6)
- Stem cell migration: a zebrafish model. (2011) (6)
- Reeling in the Zebrafish Cancer Models (2021) (6)
- Blood Histamine in Gastric Cancer and Peptic Ulcer (1943) (6)
- Identification of novel regulators of developmental hematopoiesis using Endoglin regulatory elements as molecular probes. (2016) (5)
- Conservation of Themes in Vertebrate Blood Development (1999) (5)
- Massively parallel reporter assays combined with cell-type specific eQTL informed multiple melanoma loci and identified a pleiotropic function of HIV-1 restriction gene, MX2, in melanoma promotion (2019) (5)
- Isolation and characterization of zebrafish NFE 2 (2002) (5)
- Attack of the fish clones (2002) (5)
- The zebrafish. Preface. (2011) (5)
- Piloting the zebrafish genome browser (2006) (5)
- Role of Thrombocytopenia in Hemorrhage Produced in Sarcoma 37 (1943) (5)
- PGE2 pulsing of murine bone marrow cells reduces migration of daughter monocytes/macrophages in vitro and in vivo. (2017) (5)
- Cellular barcoding to decipher clonal dynamics in disease (2022) (5)
- Identification of Basp1 as a novel angiogenesis‐regulating gene by multi‐model system studies (2021) (5)
- Genetic Analyses in Zebrafish Reveal That Angiopoietin-Like Proteins 1 and 2 Are Required for HSC Development during Embryogenesis (2008) (5)
- IGA DEFICIENCY AND SALIVARY TRANSMISSION OF HUMAN IMMUNODEFICIENCY VIRUS (1986) (4)
- Modeling cancer in the Zebrafish. (2006) (4)
- Corrigendum: Clonal fate mapping quantifies the number of haematopoietic stem cells that arise during development (2017) (4)
- Potential of zebrafish for anticancer drug screening (2008) (4)
- Purification of zebrafish erythrocytes as a means of identifying a novel regulator of haematopoiesis (2018) (4)
- A model for primary melanoma of the CNS implicates NRAS. (2013) (4)
- 'Torsade de Page': A New Cardiac-Related Illness (1983) (4)
- Small molecule screening in the zebra W sh (2006) (4)
- The zebrafish mutant gene chardonnay encodes Divalent Metal Transporter 1 ( DMT 1 ) (2002) (4)
- Chromatin immunoprecipitation and an open chromatin assay in zebrafish erythrocytes. (2016) (4)
- Chromatin Remodeling Enzyme CHD7 Negatively Regulate Hematopoietic Stem Cell Function (2013) (4)
- External signals regulate continuous transcriptional states in hematopoietic stem cells (2021) (4)
- β-Catenin Determines Developmental Stage Specific Transformation by Hox Genes. (2009) (4)
- Ageing: Stem cells on a stress-busting diet (2013) (4)
- Zebrafish as a Model for Human Diseases (2006) (3)
- Calmodulin Inhibition Rescues the Effects of Ribosomal Protein Deficiency by Modulating p53 Activity in Models of Diamond Blackfan Anemia (2012) (3)
- Efficient Transduction of Zebrafish Melanoma Cell Lines and Embryos Using Lentiviral Vectors. (2017) (3)
- Recurrent co‐alteration of HDGF and SETDB1 on chromosome 1q drives cutaneous melanoma progression and poor prognosis (2020) (3)
- Blood Flow: Metalloproteases Cut Loose in Primitive Erythrocytes (2010) (3)
- Self-renewal and differentiation at Cell Stem Cell. (2008) (3)
- Absorption of Subcuatneously Implanted Pellets of Diethylstilbestrol in Men (1943) (3)
- Centromeric markers in the zebrafish. (1999) (3)
- The Transcriptional Intermediary Factor TIF1γ Controls Erythroid Cell Fate by Specifically Regulating Transcriptional Elongation. (2009) (3)
- Clonal hematopoiesis and inflammation - the perpetual cycle. (2022) (3)
- Genetic suppressor screens in haploids. (2011) (3)
- Derivation of Hematopoietic Stem Cells from Embryonic Stem Cells. (2004) (3)
- Improving the visibility of developmental biology: time for induction and specification (2019) (3)
- Blood in the water: recent uses of zebrafish to study myeloid biology. (2020) (3)
- From blood development to disease: a paradigm for clinical translation. (2020) (3)
- A Transgenic System for Rapid Magnetic Enrichment of Rare Embryonic Cells. (2020) (3)
- Inhibition of Retinoic Acid Signaling by the cdx-hox Pathway Is Essential for Blood Cell Formation during Embryogenesis. (2004) (3)
- Ccdc 94 Protects Cells from Ionizing Radiation by Inhibiting the Expression of p 53 (2012) (3)
- Use of Zebrafish to Dissect Gene Programs Regulating Hematopoietic Stem Cells (2009) (3)
- Frascati , a Mitochondrial Solute Transporter, and Its Role in Vertebrate Erythropoiesis. (2004) (3)
- 60 – Zebra Fish and Stem Cell Research (2004) (2)
- Nucleotide stress responses in neural crest cell fate and melanoma (2021) (2)
- Hematopoietic Stem Cell Development Is Dependent on Blood Flow and Nitric Oxide Signaling (2008) (2)
- Zebrafish KLF4 is essential for hatching and haematopoiesis (2005) (2)
- Fam210b Is Required for Optimal Cellular and Mitochondrial Iron Uptake during Erythroid Differentiation (2015) (2)
- Globin switching in the zebrafish (2007) (2)
- Prostaglandin E2 Is a Potent Regulator of Vertebrate Hematopoietic Stem Cell Homeostasis. (2006) (2)
- Loss of NECTIN1 triggers melanoma dissemination upon local IGF1 depletion (2022) (2)
- Analysis of TIF1gamma Conditional Knockout Establishes a Requirement for the Differentiation of Multiple Hematopoietic Lineages (2010) (2)
- From blood development to disease: a paradigm for clinical translation (2019) (2)
- A novel myeloid-restricted zebrafish C/EBP with a potent transcriptional activation domain. (2000) (2)
- PGE 2 pulsing of murine bone marrow cells reduces migration of daughter monocytes / macrophages in vitro and in vivo (2017) (2)
- CDK13 Mutations Drive Melanoma via Accumulation of Prematurely Terminated Transcripts (2019) (2)
- Cxcl8 Expands Hematopoietic Stem and Progenitor Cells and Alters Their Interaction with the Endothelial Niche (2019) (2)
- Difference in biophysical properties of cancer-initiating cells in melanoma mutated zebrafish. (2020) (2)
- Modeling Spitz melanoma in zebrafish using sequential mutagenesis (2022) (2)
- (cid:2) A-crystallin expression prevents (cid:4) -crystallin insolubility and cataract formation in the zebrafish cloche mutant lens (2006) (2)
- Angiopoietin-Like Proteins Stimulate HSC Development Through Direct Interaction With Notch (2013) (2)
- Aging Hematopoietic Stem Cells Make Their History. (2016) (2)
- Ing4 Suppresses Quiescence and Inflammation in Hematopoietic Stem Cells (2020) (1)
- Cleavage and Polyadenylation Specificity Factor 1 Is Required for Definitive Hematopoietic Stem Cell Survival In Zebrafish. (2010) (1)
- A unique myeloid-specific C/EBP transcription factor is present in zebrafish. (1999) (1)
- Cdx 4 Is Dispensable for Murine Adult Hematopoietic Stem Cells but Promotes MLL-AF 9-Mediated Leukemogenesis (2010) (1)
- 2008 – ADULT HEMATOPOIETIC STEM CELL CLONALITY IS DETERMINED BY EMBRYONIC MACROPHAGE SENSING OF CALRETICULIN (2020) (1)
- Ing4 Regulates Hematopoiesis through Suppression of NF-Kb (2018) (1)
- HEMATOPOIESIS AND STEM CELLS Notch 1 acts via Foxc 2 to promote de fi nitive hematopoiesis via effects on hemogenic endothelium (2015) (1)
- Author response: A chemical screen in zebrafish embryonic cells establishes that Akt activation is required for neural crest development (2017) (1)
- Modeling Clonal Hematopoietic Disorders in Zebrafish Using Color Barcoding (2016) (1)
- Biomedicine. Love, honor, and protect (your liver). (2003) (1)
- Synergistic melanoma cell death mediated by inhibition of both MCL1 and BCL2 in high-risk tumors driven by NF1/PTEN loss (2021) (1)
- SPINT1 regulates the aggressiveness of skin cutaneous melanoma and its crosstalk with tumor immune microenvironment (2019) (1)
- A great match. (2012) (1)
- Development: For cloche the Bell Tolls (2016) (1)
- Niche signals regulate continuous transcriptional states in hematopoietic stem cells (2021) (1)
- Limb Specific Failure of Proliferation and Translation in the Mesenchyme Leads to Skeletal Defects in Diamond Blackfan Anemia (2022) (1)
- Identification of quantitative genetic variations regulating hematopoietic regeneration (2013) (1)
- 843 Potential role of the hematopoietic DNA-binding protein gata-1 in control of eosinophil specific gene transcription (1991) (1)
- SATB2 induction of a neural crest mesenchyme-like program drives invasion and drug resistance in melanoma (2020) (1)
- Erratum: Deficiency of glutaredoxin 5 reveals Fe–S clusters are required for vertebrate haem synthesis (2005) (1)
- Prostaglandin E2 Stimulates CREB-Mediated Modification of Histone Variant Nucleosomes at Enhancers to Promote Hematopoietic Stem Cell Fate (2018) (1)
- Dissecting melanocytes to predict melanoma (2021) (1)
- Genetic Interaction between PGE2 and the Wnt/β-Catenin Signaling Pathway Regulates Definitive HSC Development and Homeostasis. (2007) (1)
- Abstract 3871: Modeling the chromatin and transcriptional landscape of MYC and MYCN driven neuroblastoma in zebrafish (2017) (1)
- Ex Vivo Treatment of Human Cord Blood with dmPGE2 Can Safely Increase the Potential for Hematopoietic Engraftment. (2007) (1)
- Identifying Small Molecules That Overcome HoxA9-Mediated Differentiation Arrest in Acute Myeloid Leukemia (2012) (1)
- A Model System for Visualization of Whole-Body Sdf-1 Expression During Hematopoietic Cell Transplant. (2009) (1)
- IL-8 and CXCR1 Remodel the Vascular Niche to Promote Hematopoietic Stem and Progenitor Cell Engraftment (2015) (1)
- Conversion of Erythropoiesis to Myelopoiesis in Gata1-Deficient Zebrafish Embryos. (2004) (1)
- ESCs and hematopoietic fate: mixing the perfect “cocktail” (2003) (1)
- Cancer and Zebrafish: Mechanisms, Techniques, and Models: Chemical Genetics (2018) (1)
- perspectives Realizing the potential of zebrafish as a model for human disease (1)
- Chd7 Is a Cell Autonomous Regulator of Chromatin In Hematopoietic Stem Cells. (2010) (1)
- Genetic Interaction Between Angiopoietin-Like Proteins 1 and 2 and Notch Signaling During HSC Development (2010) (1)
- Ing4 Regulates Stress Hematopoiesis and Represses Self-Renewal in Multipotent Progenitor Cells (2019) (1)
- Drug discovery using induced pluripotent stem cells identifies autophagy as a therapeutic pathway for anemia (2016) (1)
- Abstract LB-335: DHODH regulates transcriptional elongation during melanoma evolution: insights from zebrafish screening (2011) (1)
- Transcription factor induction of vascular blood stem cell niches in vivo (2021) (1)
- The International Society for Stem Cell Research: a paradigm for international collaboration (2007) (1)
- Abstract 93: Tissue-specific CRISPR in zebrafish identifiesPVRL1as a novel metastasis suppressor gene in melanoma (2018) (0)
- Transcriptional Regulation of Coenzyme Q Biosynthesis By TIF1γ Drives Erythropoiesis (2019) (0)
- Book Review Master Control Genes in Development and Evolution: The homeobox story (The Terry Lectures.) By Walter J. Gehring. 236 pp., illustrated. New Haven, Conn., Yale University Press, 1998. $35. 0-300-07409-3 (1999) (0)
- Functional Consequences Of RPS29 Germline Mutations In Diamond-Blackfan Anemia (2013) (0)
- RNA helicase, DDX27 regulates proliferation and myogenic commitment of muscle stem cells (2017) (0)
- p53 Dependent and Dose Dependent Effects of Rps29 Mutation In the Zebrafish Embryo. (2010) (0)
- Blood Induction and Embryonic Formation (2014) (0)
- JAK/STATS in Zebrafish (2003) (0)
- Gene Expression Profiling of Hematopoietic Stem and Progenitor Cells in Zebrafish. (2005) (0)
- Transplantation-based screen identifies inducers of muscle progenitor cell engraftment across vertebrate species. (2023) (0)
- A Tribute to George Stamatoyannopoulos. (2016) (0)
- transplantation Prostaglandin-modulated umbilical cord blood hematopoietic stem cell (2014) (0)
- Effect of enforced expression of cxcl8 by hematopoietic stem and progenitor cells on niche interactions and hematopoietic progenitor cells in adult zebrafish. (2018) (0)
- A Screen for Regulators of Globin Switching in the Zebrafish Embryo (2012) (0)
- sprouting induced collective directional migration and angiogenic − angiopoietin-1-catenin complex in endothelial cells promotes β / ζ Formation of a PKC (2012) (0)
- A high-throughput chemical genetic screen in zebrafish establishes that prostaglandin E2 is a potent regulator of hematopoietic stem cell formation (2007) (0)
- RNA helicase DDX21 mediates nucleotide stress responses in neural crest and melanoma cells (2020) (0)
- Abstract SY16-01: Transcriptional regulation and epigenetics in zebrafish cancer. (2013) (0)
- Transferrin Acts as an Iron Sensor Upstream of BMP2b in the Zebrafish. (2007) (0)
- kinase family mediate vascular development in the zebrafish Duplicate VegfA genes and orthologues of the KDR receptor tyrosine (2013) (0)
- An Mll-Dependent Hox Program Drives Hematopoietic Progenitor Expansion (2005) (0)
- PPARα Activation Bypasses the Transcription Elongation Defect in Mutant tif1γ Erythroid Differentiation (2014) (0)
- Global Gene Expression Signatures in CD34+ Hematopoietic Cells Following Exposure to 16,16-Dimethylprostaglandin E2. (2009) (0)
- Organization that SIL Is Required for Mitotic Spindle Mutant Reveals cassiopeia The Zebra fish (2007) (0)
- Matrix metalloproteinases 2/9 are necessary for inflammatory-associated regulation of hematopoietic stem and progenitor cell production and function (2017) (0)
- Early Clonal Hematopoiesis Detected in Gata2 heterozygosity By Color-Barcoding of Hematopoietic Stem Cells in Zebrafish (2018) (0)
- Epoxyeicosatrienoic Acids Regulate Hematopoietic Stem/Progenitor Cell Fate Decision During Stress Response and Embryonic Hematopoiesis (2011) (0)
- Loss of nr4a1 abrogates Fitness of asxl1-mutant Hematopoietic Clones (2021) (0)
- Macrophages in Early Hematopoietic Development (2019) (0)
- Hematopoietic mutants identified in a saturation screen of the zebrafish genome (1995) (0)
- HEMATOPOIESIS AND STEM CELLS Dissection of vertebrate hematopoiesis using zebra fi sh thrombopoietin (2014) (0)
- Procede d'augmentation de la proliferation et/ou de la differentiation hematopoietique de cellules souches (2003) (0)
- Faculty Opinions recommendation of Ikaros expression as a marker for lymphoid progenitors during zebrafish development. (2002) (0)
- CHD7 Negatively Regulates Hematopoietic Stem Cell Potency (2012) (0)
- From development toward therapeutics, a collaborative effort on blood progenitors. (2021) (0)
- Developmental Cell Nanog-like-Mxtx 2-Nodal Pathway in Endoderm Forming (2012) (0)
- REVIEW Dissecting Hematopoiesis and Disease Using the Zebrafish (1999) (0)
- Zebrafish patient avatars in cancer biology and precision cancer therapy (2020) (0)
- A GATA-2-GPR65 Regulatory Module Controls Hematopoietic Stem Cell Generation (2015) (0)
- Engineering hematopoietic stem and progenitor cells from human pluripotent stem cells for modeling congenital anemias (2014) (0)
- CELLULAR, MOLECULAR, GENOMICS, AND BIOMEDICAL APPROACHES | Fish as Model Organisms for Medical Research (2011) (0)
- cpsf1 is required for definitive HSC survival in zebrafish (2011) (0)
- BMP and Wnt Induce Embryonic Blood Fate by Activation of the Cdx-Hox Pathway. (2007) (0)
- Morphological and genetic characterization of the zebrafish intestinal mutant, flotte lotte (flo) (2005) (0)
- Blood in the water: recent uses of zebrafish to study myeloid biology. (2020) (0)
- Erythroid colony formation from mouse embryos lacking the erythropoietin receptor is rescued by thrombopoietin (1996) (0)
- Role of Polycomb Repressive Complex 1 (PRC1) In Runx1 Mediated Gene Regulation (2010) (0)
- Derivation of adult stem cells during embryogenesis. (2006) (0)
- The for the Study of Hematopoiesis Zebrafish mutants point the way to novel genes involved in the generation of vertebrate blood cells (2007) (0)
- Abstract PL02-01: Changing cell fate in cancer: Lessons from melanoma. (2011) (0)
- Scl and Notch Act Downstream of Hedgehog Signaling to Promote Embryonic Hematopoiesis From Endothelial Cells (2011) (0)
- Apurinic/Apyrimidinic Endonuclease 1 Induced Genomic Instability Causes T-Cell Acute Lymphoblastic Leukemia in Zebrafish (2015) (0)
- Unique roles for zebrafish KLF4 and KLF12 in haematopoiesis, hatching and vasculogenesis. (2003) (0)
- Making and improving the function of adult blood stem cells (2013) (0)
- HEMATOPOIESIS AND STEM CELLS The zebra fi sh granulocyte colony-stimulating factors ( Gcsfs ) : 2 paralogous cytokines and their roles in hematopoietic development and maintenance (2013) (0)
- PADI2-mediated citrullination regulates the differences in angiogenic response (2020) (0)
- Characterizing the adult Hematopoietic Stem cell (HSC) niche in a zebrafish model for fetal bone marrow (2018) (0)
- Direct Fluorescent Visualization of HSC Competitive Repopulation in Transparent Adult Zebrafish (2008) (0)
- Pharmacological inhibition of nampt for skin inflammatory disorder treatment (2019) (0)
- Singling out blood development (2015) (0)
- 571 Identifying a novel mechanism of human skin pigmentation (2019) (0)
- Hematopoietic Stem Cell Niche Interactions In The Embryo Can Modulate The Size Of The Stem Cell Pool Into Adulthood (2013) (0)
- Abstract 2045: Identifying key molecular events at the onset of melanoma using a neural crest stem cell marker (2014) (0)
- Oncogenic CDK13 mutations impede nuclear RNA surveillance (2023) (0)
- Subject Index Vol. 89, 2000 (2000) (0)
- Stem Cell Arrival in Sites of Hematopoiesis Triggers Supportive Endothelial Niche Formation (2011) (0)
- PGE2 alters chromatin through H2A.Z-variant enhancer nucleosome modification to promote hematopoietic stem cell fate. (2023) (0)
- Development of a Limiting Dilution Assay and MHC-Matched Transplantation Model to Detect Hematopoietic Stem Cell Activity in Zebrafish (2008) (0)
- Zebrafish and Stem Cell Research (2009) (0)
- Transcription Factor Induction of Ectopic Vascular Blood Stem Cell Niches In Vivo (2019) (0)
- Author response: SATB2 induction of a neural crest mesenchyme-like program drives melanoma invasion and drug resistance (2021) (0)
- The Harvey Lectues: Delivered Under the Auspices of The Harvey Society of New York, 2006 -2007 (2010) (0)
- are abundant in zebrafish T-cell acute lymphoblastic leukemia High-throughput cell transplantation establishes that tumor-initiating cells (2010) (0)
- A Short Pulse of Prostaglandin E2 (PGE2) Induces Long Term Chromatin Changes in Hematopoietic Stem Cells Leading to Increased Self-Renewal and Engraftment (2015) (0)
- Notch Signaling Is Necessary and Sufficient for Runx1-Dependent Stem Cell Induction in the Embryonic Aorta-Gonad-Mesonephros (AGM) Region. (2004) (0)
- Calmodulin Inhibition Rescues the Effects of Ribosomal Protein Deficiency in in Vitro and In Vivo Diamond Blackfan Anemia Models (2015) (0)
- Abstract PR06: The reemergence of neural crest progenitor identity is a key event in the initiation of melanoma from a field of cancer-prone melanocytes (2016) (0)
- Cellular Barcoding of HSCs during Development Reveals Long-Term Persistence of T Cell Progenitor Clones in the Thymus (2020) (0)
- Identification of novel angiogenesis-regulating genes by genome association studies in mice (2015) (0)
- Hyperactivation of sympathetic nerves drives depletion of melanocyte stem cells (2020) (0)
- Ferroportin1-Deficient Zebrafish Treated with Iron Dextran Develop Anemia Despite Increased Macrophage Iron Stores. (2004) (0)
- Zebrafish KLF4 is essential for anterior mesendoderm/pre-polster differentiation, hatching and haematopoiesis (2005) (0)
- Transplantation-based screen uncovers inducers of muscle progenitor cell engraftment across vertebrate species (2023) (0)
- Abstract PR10: From melanocyte to melanoma: Identifying key molecular events at the onset of cancer (2014) (0)
- A chronic signaling TGFb zebrafish reporter identifies immune response in melanoma (2022) (0)
- Faculty Opinions recommendation of Hematopoietic stem cells are uniquely selective in their migratory response to chemokines. (2002) (0)
- The effects of intensive feeding on reproductive performance in laboratory zebrafish (Danio rerio) (2022) (0)
- A Zebrafish Model of Fetal Bone Marrow Provides a Dynamic View of Hematopoietic Stem Cell Niche Colonization (2016) (0)
- Screening for melanoma resistance genes in vivo (2015) (0)
- In memory of Paul Sylvain Frenette, a pioneering explorer of the hematopoietic stem cell niche who left far too early. (2021) (0)
- The Role of Chromatin Factors in Hematopoietic Development (2013) (0)
- In vivo cell tracking and quantification method in adult zebrafish (2012) (0)
- Author response: External signals regulate continuous transcriptional states in hematopoietic stem cells (2021) (0)
- Erythropoiesis Is Expressed During jak2a Divergent Embryonic Expression Patterns: Only Homologs Is Accompanied by JAK2 Gene Duplication of Zebrafish (2010) (0)
- A Short Pulse of Prostaglandin E2 (PGE2) Affects Long Term Clonal Dynamics during Hematopoietic Stem Cell Transplantation (2018) (0)
- G.P.3 Modeling congenital muscle diseases in zebrafish (2012) (0)
- A uniform format for manuscript submission (2021) (0)
- Functional conservation of erythropoietin signaling in zebrafish. Commentary (2007) (0)
- Self-renewal versus differentiation, a job for the mighty morphogens (2001) (0)
- Inducible hkRASG12D Expression in Zebrafish Hematopoietic Cells Leads to Myeloproliferative Disease. (2006) (0)
- Single-Cell Transcriptional Profiling of Zebrafish Hematopoiesis Offers Insight into Early Lymphocyte Development and Reveals Novel Immune Cell Populations (2021) (0)
- Abstract 3234: Comparative oncogenomics: identifying melanoma drivers from zebrafish to humans. (2013) (0)
- Former Officers of the Harvey Society (2010) (0)
- The zebrafishklf gene family (2001) (0)
- Med12 is an essential regulator of enhancer dynamics in hematopoietic stem cells (2016) (0)
- Abstract B035: CXCL8/CXCR1 signaling promotes angiogenesis and hematopoietic stem and progenitor cell function (2016) (0)
- Happy reunion (1996) (0)
- The RUNX1-Regulated Cebpa +37 Kb Enhancer Directs Human CD4 Transgene Expression To Long-Term Hematopoietic Stem Cells and Preferentially To Myeloid Compared With Lymphoid Or Erythroid Progenitors (2013) (0)
- Genome-Wide RNA Tomography of the Hematopoietic Stem Cell Niche in Zebrafish Reveals Unexpected Functional Macrophage-Stem Cell Interactions (2016) (0)
- Vitamin b6 plays an essential role in psoriasis (2019) (0)
- Stimulation-responsive enhancers regulate inflammatory gene activation through retention and modification of H2A.Z-variant accessible nucleosomes (2022) (0)
- Abstract PR01: Modeling clonal hematopoietic disorders in zebrafish using combinatorial mutagenesis and color barcoding (2017) (0)
- High Resolution Imaging Reveals Hematopoietic Stem Cells in the Perivascular Niche Are Anchored to Mesenchymal Stromal Cells That Orient Their Divisions (2014) (0)
- Identification of Secreted Factors with a Role in Hematopoietic Stem and Progenitor Cell Engraftment in the Developing Zebrafish (2014) (0)
- Human Umbilical Cord Blood Stem Cell Function Is Augmented by Exposure to Prostaglandin E2. (2009) (0)
- CXCR1 Mediates Dynamic Changes in the Vascular Niche and Promotes Hematopoietic Stem and Progenitor Cell Function (2016) (0)
- Requirement of Transferrin for Iron-Induced Hepcidin Expression in the Zebrafish. (2006) (0)
- Eicosanoid-GPCR Signaling Enhances Hematopoiesis and Marrow Transplant (2016) (0)
- The Use of Eicosanoids to Enhance Donor Cell Engraftment after in Utero Hematopoietic Cell Transplantation (IUHCT) (2015) (0)
- 2021 – TRANSCRIPTIONAL REGULATION OF MITOCHONDRIAL METABOLISM BY TIF1GAMMA DRIVES ERYTHROID PROGENITOR DIFFERENTIATION (2020) (0)
- William Allan Award : A Hematologist ’ s Pursuit of Hemoglobin Genetics 1 (2015) (0)
- Unexpectedly uneven: posttransplant skeletal distribution of hematopoietic stem cell clones (2014) (0)
- Review The Use of Zebrafish to Understand Immunity (2004) (0)
- Cxcl8/PKC Signaling in the Endothelial Cell Niche Regulates Long-Term Hematopoietic Stem Cell Fate (2020) (0)
- Lineage regulators and signaling transcription factors during erythropoiesis (2014) (0)
- Abstract SY42-02: Stem cell clonality and the niche (2021) (0)
- Long-Term Hematopoietic Transplantation in Zebrafish Using Immune-Matched Marrow Cells. (2009) (0)
- Abstract CT165: A phase II trial of all-trans retinoic acid (ATRA) in advanced adenoid cystic carcinoma (2021) (0)
- Abstract IA2: Developing therapeutics using the zebrafish (2014) (0)
- Chapter 38 – Zebrafish and Stem Cell Research (2013) (0)
- The Zebrafish Hypochromic Mutant [iItalic]Shiraz[/iItalic] Encodes a Novel Mitochondrial Glutaredoxin That Establishes a Link between Heme and Fe/S Production. (2004) (0)
- Identification of unique α4 chain structure and conserved anti-angiogenic activity of α3NC1 type IV collagen in zebrafish (2023) (0)
- Abstract A27: Cellular barcoding of the leukemic niche reveals an apelin-mediated clonal expansion of niche endothelial and mesenchymal stromal cell clones (2023) (0)
- Zebrafi sh in Stem Cell Research (2014) (0)
- A zebrafish model of myelodysplasia produced through tet2 genomic editing (2015) (0)
- Protein-Damaging Stresses Activate c-Jun N-Terminal Kinase via Inhibition of Its Dephosphorylation: a Novel Pathway Controlled by HSP72 (1999) (0)
- required for hematopoietic stem cell emergence A genetic screen in zebrafish defines a hierarchical network of pathways (2013) (0)
- Abstract 5152: Zebrafish models of myeloid malignancies produced through tet2 and asxl1 genomic editing (2015) (0)
- Hematopoietic and Vascular System Toxicity (2011) (0)
- BMP and WNT-Directed Transcription Factors TCF7L2/TCF4 and SMAD1 Bind to Distinct Hematopoietic-Specific Target Genes Depending on Cell Lineage (2010) (0)
- Gata-Independent Regulation of Red Cell Specific Gene Expression. (2005) (0)
- ‘Enhancing’ red cell fate through epigenetic mechanisms (2021) (0)
- 775 Hyperactivation of sympathetic nerves drives melanocyte stem cell depletion (2020) (0)
- Pathways regulating stem cell induction, self-renewal and engraftment (2016) (0)
- Modeling Diamond Blackfan Anemia in Vivo Using Human Induced Pluripotent Stem Cells (2014) (0)
- is required for definitive HSC survival in zebrafish cpsf1 (2014) (0)
- Modulators of HSC Engraftment Found in A Competitive Marrow Transplantation Screen in Adult Zebrafish. (2009) (0)
- Blood on the tracks: hematopoietic stem cell-endothelial cell interactions in homing and engraftment (2017) (0)
- Mosaic Mutagenesis In Vivo Reveals Mutant Blood Stem Cells Intrinsically Resistant to Inflammatory Mediators in Clonal Hematopoiesis (2020) (0)
- Abstract CN03-03: Use of the zebrafish for studying cancer genetics. (2013) (0)
- Contents continued (2002) (0)
- Diacylglycerol Enhances Hematopoietic Stem/Progenitor Cell Development and Engraftment Via MAP Kinase Activation (2013) (0)
- Cumulative Author Index (2002) (0)
- Target of Erythropoietin, Fam210b, Regulates Erythroid Heme Synthesis By Control of Mitochondrial Iron Import and Regulation of Fech Activity (2018) (0)
- Structure of the erythropoietin receptor in stable fibroblast transfectants. (1990) (0)
- Cloche, a gene required for generation of hematopoietic stem cell and endothelial lineages in zebrafish (1994) (0)
- Contents Vol. 89, 2000 (2000) (0)
- Piezo1-Sensitive Biomechanical Pulsation Stimulates Long-Term Hematopoietic Stem Cell Formation (2018) (0)
- zebrafish Characterization of immune-matched hematopoietic transplantation in (2011) (0)
- Visualizing the Effects of Chemicals On Hematopoietic Stem Cell Engraftment in an Endogenous Niche (2012) (0)
- Epigenetic Regulation in Melanoma (2019) (0)
- hematopoietic mesoderm in Xenopus laevis The role of BMP-4 and GATA-2 in the induction and differentiation of (2011) (0)
- The genetic heterogeneity and mutational burden of engineered melanomas in zebrafish models (2013) (0)
- NOTCH signaling specifies arterial-type definitive hemogenic endothelium from human pluripotent stem cells (2018) (0)
- Transcription Factor Integration from Pathways Regulating Adult Blood Stem Cell Production and Self-Renewal. (2008) (0)
- Blood Notch-Foxc2 2015 All with Suppl (2015) (0)
- Retinoic Acid Blockade Increases Primitive Blood Cell Formation in cdx4 Mutant Zebrafish Embryos, Murine Yolk Sac Explants and Differentiated Embryonic Stem Cells. (2007) (0)
- Transcriptional Signaling Centers Govern Human Erythropoiesis and Harbor Genetic Variations of Red Blood Cell Traits (2018) (0)
- Zebrafish modeling reveals that SPINT1 regulates the aggressiveness of skin cutaneous melanoma and its crosstalk with tumor immune microenvironment (2019) (0)
- Abstract PR04: Transcriptional regulation of mitochondrial metabolism by TIF1γ drives erythroid progenitor differentiation (2020) (0)
- Blood Cell: Lineage Restriction (2001) (0)
- Taking the Stem Cell Debate to the Public (2004) (0)
- Modeling Diamond Blackfan Anemia and p53 Activation in the Zebrafish (2016) (0)
- Faculty Opinions recommendation of Developmental control of blood cell migration by the Drosophila VEGF pathway. (2002) (0)
- Stu Orkin is a superhero. (2018) (0)
- Edinburgh Research Explorer PRL3-DDX21 transcriptional control of endolysosomal genes restricts melanocyte stem cell differentiation (2020) (0)
- Allan J. Erslev, M.D.: Truly a Great Dane (1919–2003) (2004) (0)
- Modeling congenital muscle diseases in zebrafish (2012) (0)
- A Cdx 4-Sall 4 Regulatory Module Controls the Transition from Mesoderm Formation to Embryonic Hematopoiesis Citation (2013) (0)
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