Leonid Sazanov
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Leonid Sazanovbiology Degrees
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Molecular Biology
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Biochemistry
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Leonid Sazanovphysics Degrees
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Biology Physics
Leonid Sazanov's Degrees
- PhD Biochemistry Moscow State University
Why Is Leonid Sazanov Influential?
(Suggest an Edit or Addition)According to Wikipedia, Leonid A. Sazanov is a professor at the Institute of Science and Technology Austria . Sazanov research explores the structure and function of large membrane protein complexes from the domain of bioenergetics. These molecular machines interconvert redox energy and proton motive force across biological membranes using a variety of mechanisms.
Leonid Sazanov's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Structure of the Hydrophilic Domain of Respiratory Complex I from Thermus thermophilus (2006) (727)
- Crystal structure of the entire respiratory complex I (2013) (677)
- The architecture of respiratory complex I (2010) (599)
- Identification of a functional respiratory complex in chloroplasts through analysis of tobacco mutants containing disrupted plastid ndh genes (1998) (473)
- A giant molecular proton pump: structure and mechanism of respiratory complex I (2015) (404)
- Atomic structure of the entire mammalian mitochondrial complex I (2016) (378)
- The architecture of respiratory supercomplexes (2016) (361)
- Structure of the membrane domain of respiratory complex I (2011) (341)
- Structural Basis for the Mechanism of Respiratory Complex I* (2009) (226)
- Clarifying the supercomplex: the higher-order organization of the mitochondrial electron transport chain (2017) (219)
- Respiratory complex I: mechanistic and structural insights provided by the crystal structure of the hydrophilic domain. (2007) (210)
- The plastid ndh genes code for an NADH-specific dehydrogenase: isolation of a complex I analogue from pea thylakoid membranes. (1998) (197)
- Organization of Iron-Sulfur Clusters in Respiratory Complex I (2005) (190)
- Resolution of the membrane domain of bovine complex I into subcomplexes: implications for the structural organization of the enzyme. (2000) (183)
- The chloroplast Ndh complex mediates the dark reduction of the plastoquinone pool in response to heat stress in tobacco leaves (1998) (130)
- Structures of Respiratory Supercomplex I+III2 Reveal Functional and Conformational Crosstalk (2019) (122)
- The coupling mechanism of respiratory complex I - a structural and evolutionary perspective. (2012) (111)
- The coupling mechanism of mammalian respiratory complex I (2020) (103)
- Structure of the bacterial type II NADH dehydrogenase: a monotopic membrane protein with an essential role in energy generation (2014) (95)
- Respiratory complex I: 'steam engine' of the cell? (2011) (93)
- The assembly, regulation and function of the mitochondrial respiratory chain (2021) (91)
- Mammalian Mitochondrial Complex I Structure and Disease-Causing Mutations. (2018) (90)
- Evolution of Respiratory Complex I (2010) (86)
- Substrate-induced Conformational Change in Bacterial Complex I* (2004) (82)
- Projection structure of the membrane domain of Escherichia coli respiratory complex I at 8 A resolution. (2007) (80)
- Cryo-EM structure of the entire mammalian F-type ATP synthase (2020) (80)
- A Role for Native Lipids in the Stabilization and Two-dimensional Crystallization of the Escherichia coli NADH-Ubiquinone Oxidoreductase (Complex I)* (2003) (78)
- Review and meta‐analysis of natural selection in mitochondrial complex I in metazoans (2015) (73)
- The Location of NuoL and NuoM Subunits in the Membrane Domain of the Escherichia coli Complex I (2003) (73)
- Cryo-electron crystallography of two sub-complexes of bovine complex I reveals the relationship between the membrane and peripheral arms. (2000) (68)
- Structure of bacterial respiratory complex I. (2016) (62)
- Identification of a novel subunit of respiratory complex I from Thermus thermophilus. (2006) (61)
- The mechanism of coupling between electron transfer and proton translocation in respiratory complex I (2014) (54)
- Single particle analysis confirms distal location of subunits NuoL and NuoM in Escherichia coli complex I. (2007) (53)
- Mitochondrial mutations and metabolic adaptation in pancreatic cancer (2017) (50)
- Detection and characterization of a complex I-like NADH-specific dehydrogenase from pea thylakoids. (1996) (49)
- Key role of quinone in the mechanism of respiratory complex I (2020) (48)
- Naphthylphthalamic acid associates with and inhibits PIN auxin transporters (2020) (47)
- Three-dimensional structure of respiratory complex I from Escherichia coli in ice in the presence of nucleotides. (2008) (44)
- Structure and mechanism of mitochondrial proton-translocating transhydrogenase (2019) (43)
- Structure and conformational plasticity of the intact Thermus thermophilus V/A-type ATPase (2019) (38)
- Chemical and NADH-induced, ROS-dependent, cross-linking between subunits of complex I from Escherichia coli and Thermus thermophilus. (2008) (37)
- Structure of Complex I (2012) (34)
- Reversible FMN dissociation from Escherichia coli respiratory complex I. (2016) (33)
- Structure of Escherichia coli OmpF porin from lipidic mesophase. (2012) (31)
- Gaining mass: the structure of respiratory complex I-from bacterial towards mitochondrial versions. (2015) (29)
- Structure and mechanism of respiratory complex I (2012) (28)
- A long road towards the structure of respiratory complex I, a giant molecular proton pump. (2013) (26)
- Purification of Ovine Respiratory Complex I Results in a Highly Active and Stable Preparation* (2016) (24)
- Structure and mechanism of the Mrp complex, an ancient cation/proton antiporter (2020) (23)
- Structure and assembly of the mammalian mitochondrial supercomplex CIII2CIV (2021) (23)
- Charge transfer and chemo-mechanical coupling in respiratory complex I. (2020) (19)
- Structure of respiratory complex I – An emerging blueprint for the mechanism (2022) (17)
- Cryo-EM grid optimization for membrane proteins (2021) (15)
- Presence of a large protein complex containing the ndhK gene product and possessing NADH-specific dehydrogenase activity in thylakoid membranes of higher plant chloroplasts (1995) (15)
- A structural perspective on respiratory complex I : structure and function of NADH:ubiquinone oxidoreductase (2012) (14)
- NDUFS4 deletion triggers loss of NDUFA12 in Ndufs4-/- mice and Leigh syndrome patients: A stabilizing role for NDUFAF2. (2020) (13)
- A Structural Perspective on Respiratory Complex I (2012) (12)
- Proton-translocating transhydrogenase in bacteria. (1993) (11)
- A universal coupling mechanism of respiratory complex I (2022) (9)
- Radiolysis of nitrous oxide adsorbed on alumina ionic mechanism of radiolysis of nitrous oxide on alumina with small surface areas (1982) (3)
- The coupling mechanism of respiratory complex I (2022) (3)
- Site-directed mutagenesis of residues involved in proton translocation by Escherichia coli complex I (2012) (2)
- Architecture of tight respirasome (2016) (2)
- Crystallisation of the membrane domain of complex I from Escherichia coli (2010) (1)
- Chapter 2:Structure of Respiratory Complex I: “Minimal” Bacterial and “De luxe” Mammalian Versions (2017) (1)
- A novel chaperone-like subunit of complex I from Thermus thermophilus (2012) (1)
- Proton translocation by Thermus thermophilus complex I (2012) (1)
- Thermus thermophilus V/A-type ATPase/synthase, rotational state 1 (2019) (1)
- Most mitochondrial dGTP is tightly bound to respiratory complex I through the NDUFA10 subunit (2022) (1)
- Ovine respiratory supercomplex I+III2 closed class. (2019) (1)
- Entire Respiratory Complex I from Thermus Thermophilus (2014) (1)
- Crystal structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus (2006) (1)
- Mitochondrial mutations and metabolic adaptation in pancreatic cancer (2017) (1)
- Purification of a seven-subunit Mrp-type sodium-proton antiporter (2018) (0)
- Complex I during turnover, open3 (2020) (0)
- Ovine respiratory complex I FRC closed class 1 (2019) (0)
- Respiratory complex I from Thermus thermophilus with bound Aureothin. (2020) (0)
- Complex I inhibited by rotenone, open3 (2020) (0)
- Crystal structure of the membrane domain of respiratory complex I from E. coli at 3.0 angstrom resolution (2011) (0)
- Author Correction: A universal coupling mechanism of respiratory complex I (2022) (0)
- Respiratory complex I from Thermus thermophilus with bound Pyridaben. (2020) (0)
- Structure of the Mrp antiporter complex (2020) (0)
- Deactive complex I, open1 (2020) (0)
- Purification and characterisation of complex I from Paracoccus denitrificans (2010) (0)
- From the 'black box' to 'domino effect' mechanism: what have we learned from the structures of respiratory complex I. (2023) (0)
- Crystal structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus, oxidized, 2 mol/ASU (2009) (0)
- Structure, function and assembly mechanism of the mammalian mitochondrial supercomplex CIII2CIV (2022) (0)
- Hydrophilic Domain of Respiratory Complex I from Thermus thermophilus (2011) (0)
- Ovine respiratory complex I FRC open class 5 (2019) (0)
- Crystal structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus, oxidized, 4 mol/ASU, re-refined to 3.15 angstrom resolution (2009) (0)
- NADH binding to complex I: Implications for the mechanism (2010) (0)
- Ovine ATP synthase 1a state (2020) (0)
- The mechanism of mammalian respiratory complex I (2018) (0)
- Structure and mechanism of respiratory complex I, a giant molecular proton pump (2013) (0)
- Characterisation and crystallisation of intact complex I from Thermus thermophilus (2010) (0)
- Author response: Structure and mechanism of the Mrp complex, an ancient cation/proton antiporter (2020) (0)
- Complex I with NADH, open3 (2020) (0)
- Probing the conformational heterogeneity of complex I by combination of cryo-electron microscopy, crystallography and normal mode analysis (2018) (0)
- Structure of ovine transhydrogenase in the presence of NADP+ in a ""double face-down"" conformation (2019) (0)
- Native complex I, open3 (2020) (0)
- Structural investigation of E. coli complex I as a mechanistic model (2022) (0)
- Structure of Respiratory Complex I (2011) (0)
- Crystal Structure of E.coli OmpF porin in lipidic cubic phase: space group P1 (2012) (0)
- Complex I inhibited by rotenone, closed (2020) (0)
- Faculty Opinions recommendation of Ribosome structures to near-atomic resolution from thirty thousand cryo-EM particles. (2013) (0)
- The efficiency of using fluorine-containing surfactants for property modification of polyurethanes filled with chalk (2014) (0)
- Isolated complex I class refinement from Ovine respiratory supercomplex I+III2 (2019) (0)
- Crystal structure of the membrane domain of respiratory complex I from Escherichia coli (2010) (0)
- Ovine respiratory supercomplex I+III2 open class 1 (2019) (0)
- Interaction of complex I from Thermus thermophilus with quinone and quinone-like inhibitors (2012) (0)
- Complex I during turnover, open1 (2020) (0)
- Complex I inhibited by rotenone, open1 (2020) (0)
- Membrane domain of closed complex I during turnover (2020) (0)
- Structure of ovine transhydrogenase in the presence of NADP+ in a ""single face-down"" conformation (2019) (0)
- Thermus thermophilus V/A-type ATPase/synthase, rotational state 2 (2019) (0)
- Crystal structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus, reduced, 2 mol/ASU, with bound NADH (2009) (0)
- Structural basis for the coupling mechanism of respiratory complex I, a giant molecular proton pump (2014) (0)
- Deactive complex I, open4 (2020) (0)
- CI Membrane Arm focused refinement from Ovine respiratory SC I+III2 (2019) (0)
- The architecture of bacterial respiratory complex I (2010) (0)
- Structure of ovine transhydrogenase in the apo state (2019) (0)
- Thermus thermophilus V/A-type ATPase/synthase, rotational state 1R (2019) (0)
- Respiratory complex I from Thermus thermophilus, NADH dataset, major state (2020) (0)
- Respiratory complex I from Thermus thermophilus with bound NADH (2020) (0)
- Architecture of loose respirasome (2016) (0)
- Thermus thermophilus Complex I from Structure of the Hydrophilic Domain of Respiratory (2007) (0)
- Architecture of supercomplex I-III2 (2016) (0)
- Complex I with NADH, open2 (2020) (0)
- Complex I during turnover, closed (2020) (0)
- Deactive complex I, open2 (2020) (0)
- Native complex I, open1 (2020) (0)
- Murine supercomplex CIII2CIV in the mature unlocked conformation (2021) (0)
- Complex I with NADH, open1 (2020) (0)
- Murine CIII2 focus-refined from supercomplex CICIII2 (2021) (0)
- Cryo-EM studies on mechanism of respiratory complex I (2022) (0)
- Deactive complex I, open3 (2020) (0)
- Purification and characterization of mitochondrial complex I from Neurospora crassa for structural studies (2014) (0)
- Respiratory complex I from Thermus thermophilus, NAD+ dataset, minor state (2020) (0)
- Native complex I, open2 (2020) (0)
- Thermus thermophilus V/A-type ATPase/synthase, rotational state 3 (2019) (0)
- Structure and mechanism of mitochondrial proton-translocating transhydrogenase (2019) (0)
- Fo domain of Ovine ATP synthase (2020) (0)
- Structure of bacterial type II NADH dehydrogenase from Caldalkalibacillus thermarum at 2.15A resolution (2014) (0)
- Structural characterisation of murine F1F0 ATP-synthase (2022) (0)
- Murine supercomplex CIII2CIV in the intermediate locked conformation (2021) (0)
- Complex I with NADH, closed (2020) (0)
- Complex I inhibited by rotenone, open2 (2020) (0)
- Complex III2 focused refinement from Ovine respiratory supercomplex I+III2 (2019) (0)
- Native complex I, closed (2020) (0)
- Peripheral domain of open complex I during turnover (2020) (0)
- Coupling mechanism of complex I (2018) (0)
- Respiratory complex I from Thermus thermophilus (2020) (0)
- Crystal structure of respiratory complex I from Thermus thermophilus (2010) (0)
- Entire ovine respiratory complex I (2016) (0)
- Murine supercomplex CIII2CIV in the assembled locked conformation (2021) (0)
- Crystal structure of the membrane domain of respiratory complex I from Thermus thermophilus (2013) (0)
- S4/3 Structural studies on bacterial complex I (2008) (0)
- Functional and Structural Characterization of Isolated Mammalian Mitochondrial Respiratory Supercomplex I+III2 (2018) (0)
- Crystal structure of E.coli OmpF porin in lipidic cubic phase: space group H32, large unit cell (2012) (0)
- Thermus thermophilus V/A-type ATPase/synthase, rotational state 1L (2019) (0)
- Membrane domain of open complex I during turnover (2020) (0)
- Mathematical model of the regulation of photosynthesis - effect of exogenous factors, damping oscillations (1988) (0)
- The assembly, regulation and function of the mitochondrial respiratory chain (2021) (0)
- CI Peripheral Arm focused refinement from Ovine respiratory SC I+III2 (2019) (0)
- Respiratory complex I from Thermus thermophilus with bound Piericidin A (2020) (0)
- Complex I during turnover, open2 (2020) (0)
- Respiratory complex I from Thermus thermophilus, NADH dataset, minor state (2020) (0)
- Mutagenesis of complex I from Thermus thermophilus (2014) (0)
- Respiratory complex I from Thermus thermophilus with bound Decyl-Ubiquinone (2020) (0)
- The Ycf48 accessory factor occupies the site of the oxygen-evolving manganese cluster during photosystem II biogenesis (2022) (0)
- Respiratory complex I from Thermus thermophilus, NAD+ dataset, major state (2020) (0)
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