Leslie Michael Shaw
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Leslie Michael Shawbiology Degrees
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Neuroscience
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Biology
Leslie Michael Shaw's Degrees
- Bachelors Biology University of California, Berkeley
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(Suggest an Edit or Addition)Leslie Michael Shaw's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade (2010) (3896)
- Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers (2013) (3207)
- Early role of vascular dysregulation on late-onset Alzheimer's disease based on multifactorial data-driven analysis (2016) (716)
- Alzheimer's Disease Neuroimaging Initiative (ADNI) (2010) (712)
- Activation of Phosphoinositide 3-OH Kinase by the α6β4 Integrin Promotes Carcinoma Invasion (1997) (626)
- MRI of hippocampal volume loss in early Alzheimer's disease in relation to ApoE genotype and biomarkers (2008) (579)
- Prediction of MCI to AD conversion, via MRI, CSF biomarkers, and pattern classification (2011) (540)
- Vascular endothelial growth factor is an autocrine survival factor for neuropilin-expressing breast carcinoma cells. (2001) (466)
- Brain beta-amyloid measures and magnetic resonance imaging atrophy both predict time-to-progression from mild cognitive impairment to Alzheimer’s disease (2010) (464)
- Diagnosis-independent Alzheimer disease biomarker signature in cognitively normal elderly people. (2010) (446)
- Relationships between biomarkers in aging and dementia (2009) (440)
- The role of NFAT transcription factors in integrin-mediated carcinoma invasion (2002) (417)
- Clinical core of the Alzheimer's disease neuroimaging initiative: Progress and plans (2010) (395)
- Prediction of conversion from mild cognitive impairment to Alzheimer's disease dementia based upon biomarkers and neuropsychological test performance (2012) (388)
- MRI and CSF biomarkers in normal, MCI, and AD subjects (2009) (384)
- CSF biomarkers of Alzheimer’s disease concord with amyloid-β PETand predict clinical progression: A study of fully automated immunoassays in BioFINDER and ADNI cohorts (2018) (380)
- Association of cerebrospinal fluid β-amyloid 1-42, T-tau, P-tau181, and α-synuclein levels with clinical features of drug-naive patients with early Parkinson disease. (2013) (342)
- Plasma tau in Alzheimer disease (2016) (337)
- GWAS of Cerebrospinal Fluid Tau Levels Identifies Risk Variants for Alzheimer’s Disease (2013) (332)
- Drg-1 as a differentiation-related, putative metastatic suppressor gene in human colon cancer. (2000) (331)
- Total and phosphorylated tau protein as biological markers of Alzheimer’s disease (2010) (328)
- Current state of Alzheimer’s fluid biomarkers (2018) (327)
- Association of Cerebrospinal Fluid Neurofilament Light Concentration With Alzheimer Disease Progression. (2016) (326)
- Biomarkers of neurodegeneration for diagnosis and monitoring therapeutics (2007) (321)
- Therapeutic Drug Monitoring of Mycophenolate Mofetil in Transplantation (2006) (313)
- Update on the biomarker core of the Alzheimer's Disease Neuroimaging Initiative subjects (2010) (311)
- Mycophenolic acid binding to human serum albumin: characterization and relation to pharmacodynamics. (1995) (306)
- Community Exposure to Perfluorooctanoate: Relationships Between Serum Concentrations and Exposure Sources (2006) (303)
- Comparing positron emission tomography imaging and cerebrospinal fluid measurements of β‐amyloid (2013) (300)
- Standardization of preanalytical aspects of cerebrospinal fluid biomarker testing for Alzheimer's disease diagnosis: A consensus paper from the Alzheimer's Biomarkers Standardization Initiative (2012) (295)
- Altered bile acid profile associates with cognitive impairment in Alzheimer's disease—An emerging role for gut microbiome (2018) (288)
- Qualification of the analytical and clinical performance of CSF biomarker analyses in ADNI (2011) (275)
- The activation dependent adhesion of macrophages to laminin involves cytoskeletal anchoring and phosphorylation of the alpha 6 beta 1 integrin (1990) (265)
- The α6β4 integrin and epithelial cell migration (2001) (260)
- The major non-integrin laminin binding protein of macrophages is identical to carbohydrate binding protein 35 (Mac-2). (1990) (250)
- Activation of Jak/STAT proteins involved in signal transduction pathway mediated by receptor for interleukin 2 in malignant T lymphocytes derived from cutaneous anaplastic large T-cell lymphoma and Sezary syndrome. (1996) (238)
- Activation of phosphoinositide 3-OH kinase by the alpha6beta4 integrin promotes carcinoma invasion. (1997) (236)
- Mycophenolic Acid Pharmacodynamics and Pharmacokinetics Provide a Basis for Rational Monitoring Strategies (2003) (235)
- The Parkinson's progression markers initiative (PPMI) – establishing a PD biomarker cohort (2018) (234)
- Understanding disease progression and improving Alzheimer's disease clinical trials: Recent highlights from the Alzheimer's Disease Neuroimaging Initiative (2018) (225)
- The immunosuppressive macrolide RAD inhibits growth of human Epstein-Barr virus-transformed B lymphocytes in vitro and in vivo: A potential approach to prevention and treatment of posttransplant lymphoproliferative disorders. (2000) (224)
- Evidence for ordering of Alzheimer disease biomarkers. (2011) (217)
- Independent information from cerebrospinal fluid amyloid-β and florbetapir imaging in Alzheimer's disease. (2015) (211)
- Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the World Federation of Societies of Biological Psychiatry (2017) (209)
- Guidelines for the standardization of preanalytic variables for blood-based biomarker studies in Alzheimer's disease research (2015) (205)
- Cerebrospinal fluid neurogranin: relation to cognition and neurodegeneration in Alzheimer's disease. (2015) (204)
- Plasma multianalyte profiling in mild cognitive impairment and Alzheimer disease (2012) (202)
- Identification of Insulin Receptor Substrate 1 (IRS-1) and IRS-2 as Signaling Intermediates in the α6β4 Integrin-Dependent Activation of Phosphoinositide 3-OH Kinase and Promotion of Invasion (2001) (193)
- Plasma biomarkers associated with the apolipoprotein E genotype and Alzheimer disease. (2012) (189)
- Human Alzheimer and Inflammation Biomarkers after Anesthesia and Surgery (2011) (189)
- Integrin (α6β4) regulation of eIF-4E activity and VEGF translation (2002) (185)
- MRI and CSF biomarkers in normal, MCI, and AD subjects (2009) (181)
- Community Exposure to Perfluorooctanoate: Relationships Between Serum Levels and Certain Health Parameters (2006) (180)
- Consensus document: Hawk's Cay meeting on therapeutic drug monitoring of cyclosporine. (1990) (174)
- Alzheimer's Disease Neuroimaging Initiative: A one-year follow up study using tensor-based morphometry correlating degenerative rates, biomarkers and cognition (2009) (173)
- CSF biomarkers cutoffs: the importance of coincident neuropathological diseases (2012) (171)
- Longitudinal change in CSF Tau and Aβ biomarkers for up to 48 months in ADNI (2013) (170)
- Longitudinal change of biomarkers in cognitive decline. (2011) (169)
- CSF biomarkers associated with disease heterogeneity in early Parkinson’s disease: the Parkinson’s Progression Markers Initiative study (2016) (169)
- Novel CSF biomarkers for Alzheimer’s disease and mild cognitive impairment (2010) (168)
- A description of two procedures which avoid the use of extreme pH conditions for the resolution of components isolated from chromatins prepared from pig cerebellar and pituitary nuclei. (1970) (168)
- Cannabinoids and appetite stimulation (1994) (166)
- Release of cAMP Gating by the α6β4 Integrin Stimulates Lamellae Formation and the Chemotactic Migration of Invasive Carcinoma Cells (1998) (165)
- Comparison of analytical platforms for cerebrospinal fluid measures of β-amyloid 1-42, total tau, and p-tau181 for identifying Alzheimer disease amyloid plaque pathology. (2011) (164)
- Limited sampling strategy for the estimation of mycophenolic acid area under the curve in adult renal transplant patients treated with concomitant tacrolimus. (2002) (161)
- Immunosuppressive TOR kinase inhibitor everolimus (RAD) suppresses growth of cells derived from posttransplant lymphoproliferative disorder at allograft-protecting doses (2003) (157)
- Expression and function of the insulin receptor substrate proteins in cancer (2009) (154)
- Ethylene glycol poisoning: toxicokinetic and analytical factors affecting laboratory diagnosis. (1998) (153)
- The Effect of Renal Insufficiency on Mycophenolic Acid Protein Binding (1999) (152)
- Altered bile acid profile in mild cognitive impairment and Alzheimer's disease: Relationship to neuroimaging and CSF biomarkers (2018) (151)
- Increased soluble TREM2 in cerebrospinal fluid is associated with reduced cognitive and clinical decline in Alzheimer’s disease (2019) (150)
- Mouse egg integrin alpha 6 beta 1 functions as a sperm receptor. (1995) (149)
- A platform for discovery: The University of Pennsylvania Integrated Neurodegenerative Disease Biobank (2014) (148)
- Clinical and multimodal biomarker correlates of ADNI neuropathological findings (2013) (147)
- Clinical Utility of Monitoring Tacrolimus Blood Concentrations in Liver Transplant Patients (2001) (147)
- Characterizing Alzheimer's disease using a hypometabolic convergence index (2011) (145)
- Early increase of CSF sTREM2 in Alzheimer’s disease is associated with tau related-neurodegeneration but not with amyloid-β pathology (2019) (141)
- Cognitive decline and reduced survival in C9orf72 expansion frontotemporal degeneration and amyotrophic lateral sclerosis (2012) (140)
- The role of apolipoprotein E (APOE) genotype in early mild cognitive impairment (E-MCI) (2013) (137)
- GLI1 regulates a novel neuropilin-2/α6β1 integrin based autocrine pathway that contributes to breast cancer initiation (2013) (136)
- Mycophenolic Acid Area under the Curve Values in African American and Caucasian Renal Transplant Patients Are Comparable (2000) (136)
- Clinical utility and analytical challenges in measurement of cerebrospinal fluid amyloid-β(1-42) and τ proteins as Alzheimer disease biomarkers. (2013) (136)
- Integrin (alpha 6 beta 4) regulation of eIF-4E activity and VEGF translation: a survival mechanism for carcinoma cells. (2002) (134)
- Therapeutic monitoring of mycophenolic acid. A consensus panel report. (1998) (132)
- Appropriate use criteria for lumbar puncture and cerebrospinal fluid testing in the diagnosis of Alzheimer’s disease (2018) (132)
- Global standardization measurement of cerebral spinal fluid for Alzheimer's disease: An update from the Alzheimer's Association Global Biomarkers Consortium (2013) (131)
- Association of Cerebrospinal Fluid Neurofilament Light Protein Levels With Cognition in Patients With Dementia, Motor Neuron Disease, and Movement Disorders (2019) (130)
- THERAPEUTIC DRUG MONITORING OF CYCLOSPORINE AND TACROLIMUS (1998) (129)
- Simultaneous determination of mycophenolic acid and its glucuronide in human plasma using a simple high-performance liquid chromatography procedure. (1998) (127)
- The alpha 6 beta 4 integrin and epithelial cell migration. (2001) (126)
- Involvement of Insulin Receptor Substrate 2 in Mammary Tumor Metastasis (2004) (126)
- 3D PIB and CSF biomarker associations with hippocampal atrophy in ADNI subjects (2010) (126)
- Pharmacokinetics and concentration-control investigations of mycophenolic acid in adults after transplantation. (2000) (126)
- Shapes of the trajectories of 5 major biomarkers of Alzheimer disease. (2012) (126)
- Evaluation of prostate-specific antigen and prostatic acid phosphatase as prostate cancer markers. (1986) (122)
- Plasma amyloid beta measurements - a desired but elusive Alzheimer's disease biomarker (2013) (121)
- Approved Recommendation (1985) on IFCC Methods for the Measurement of Catalytic Concentration of Enzymes (2009) (118)
- Current opinions on therapeutic drug monitoring of immunosuppressive drugs. (1999) (117)
- Genome-wide association study identifies four novel loci associated with Alzheimer’s endophenotypes and disease modifiers (2017) (117)
- Cognitive reserve and Alzheimer's disease biomarkers are independent determinants of cognition (2011) (116)
- Integration and relative value of biomarkers for prediction of MCI to AD progression: Spatial patterns of brain atrophy, cognitive scores, APOE genotype and CSF biomarkers☆☆☆ (2013) (115)
- Mapping correlations between ventricular expansion and CSF amyloid and tau biomarkers in 240 subjects with Alzheimer's disease, mild cognitive impairment and elderly controls (2009) (114)
- IFCC methods for the measurement of catalytic concentration of enzymes Part 5. IFCC method for alkaline phosphatase (orthophosphoric-monoester phosphohydrolase, alkaline optimum, EC 3.1.3.1). (1983) (114)
- Longitudinal Change of Clinical and Biological Measures in Early Parkinson's Disease: Parkinson's Progression Markers Initiative Cohort (2018) (113)
- Multicenter, Randomized Study of the Use of Everolimus With Tacrolimus After Renal Transplantation Demonstrates its Effectiveness (2008) (112)
- Mycophenolate Mofetil: A Report of the Consensus Panel (1995) (112)
- The Rationale for and Limitations of Therapeutic Drug Monitoring for Mycophenolate Mofetil in Transplantation (2005) (112)
- Pharmacokinetic, pharmacodynamic, and outcome investigations as the basis for mycophenolic acid therapeutic drug monitoring in renal and heart transplant patients. (2001) (110)
- Tumor cell invasion assays. (2005) (108)
- Canadian Consensus Meeting on cyclosporine monitoring: report of the consensus panel. (1990) (107)
- RAFTK/Pyk2 tyrosine kinase mediates the association of p190 RhoGAP with RasGAP and is involved in breast cancer cell invasion (2000) (107)
- The insulin receptor substrate (IRS) proteins (2011) (107)
- Association of Altered Liver Enzymes With Alzheimer Disease Diagnosis, Cognition, Neuroimaging Measures, and Cerebrospinal Fluid Biomarkers (2019) (106)
- Alzheimer's disease cerebrospinal fluid biomarker in cognitively normal subjects. (2015) (106)
- Cerebrospinal fluid neurogranin concentration in neurodegeneration: relation to clinical phenotypes and neuropathology (2018) (106)
- The integrin alpha 6 beta 1 promotes the survival of metastatic human breast carcinoma cells in mice. (1997) (105)
- Divergent Roles for IRS-1 and IRS-2 in Breast Cancer Metastasis (2007) (104)
- Cerebrospinal fluid, plasma, and saliva in the BioFIND study: Relationships among biomarkers and Parkinson's disease Features (2017) (104)
- Cardiovascular risk factors, cortisol, and amyloid-β deposition in Alzheimer's Disease Neuroimaging Initiative (2012) (103)
- Relations between brain tissue loss, CSF biomarkers, and the ApoE genetic profile: a longitudinal MRI study (2010) (101)
- Pharmacokinetics of mycophenolic acid in renal insufficiency. (2000) (100)
- Regulation of Mitogen-activated Protein Kinase Activation by the Cytoplasmic Domain of the α6 Integrin Subunit* (1998) (99)
- CSF Aβ1-42 - an excellent but complicated Alzheimer's biomarker - a route to standardisation. (2017) (99)
- Comparison of cerebrospinal fluid levels of tau and Aβ 1-42 in Alzheimer disease and frontotemporal degeneration using 2 analytical platforms. (2012) (98)
- Regulated splicing of the α6 integrin cytoplasmic domain determines the fate of breast cancer stem cells. (2014) (98)
- Suppression of Insulin Receptor Substrate 1 (IRS-1) Promotes Mammary Tumor Metastasis (2006) (98)
- Inside-out integrin signaling in macrophages. Analysis of the role of the alpha 6A beta 1 and alpha 6B beta 1 integrin variants in laminin adhesion by cDNA expression in an alpha 6 integrin-deficient macrophage cell line. (1993) (97)
- Functional brain architecture is associated with the rate of tau accumulation in Alzheimer’s disease (2020) (96)
- Qualification of a surrogate matrix-based absolute quantification method for amyloid-β₄₂ in human cerebrospinal fluid using 2D UPLC-tandem mass spectrometry. (2014) (96)
- Evidence that Distinct States of the Integrin α6β1 Interact with Laminin and an ADAM (1999) (95)
- Diagnostic accuracy of CSF Ab42 and florbetapir PET for Alzheimer's disease (2014) (93)
- Function of the integrin α6β1 in metastatic breast carcinoma cells assessed by expression of a dominant-negative receptor (1996) (93)
- Transforming cerebrospinal fluid Aβ42 measures into calculated Pittsburgh compound B units of brain Aβ amyloid (2011) (92)
- Human pharmacokinetics of WR-2721. (1986) (92)
- Machine learning for comprehensive forecasting of Alzheimer’s Disease progression (2018) (92)
- Mycophenolic acid concentrations are associated with cardiac allograft rejection. (2000) (92)
- Neuronal injury biomarkers and prognosis in ADNI subjects with normal cognition (2014) (91)
- Drosophila Sirt2/mammalian SIRT3 deacetylates ATP synthase β and regulates complex V activity (2014) (90)
- Nonlinear Association Between Cerebrospinal Fluid and Florbetapir F-18 β-Amyloid Measures Across the Spectrum of Alzheimer Disease. (2015) (89)
- CSF α-synuclein improves diagnostic and prognostic performance of CSF tau and Aβ in Alzheimer’s disease (2013) (89)
- Reference measurement procedures for Alzheimer's disease cerebrospinal fluid biomarkers: definitions and approaches with focus on amyloid β42. (2012) (85)
- Longitudinal CSF biomarkers in patients with early Parkinson disease and healthy controls (2017) (85)
- Simultaneous analysis of cerebrospinal fluid biomarkers using microsphere-based xMAP multiplex technology for early detection of Alzheimer's disease. (2012) (84)
- Predicting clinical decline and conversion to Alzheimer’s disease or dementia using novel Elecsys Aβ(1–42), pTau and tTau CSF immunoassays (2019) (84)
- Integrin Laminin Receptors and Breast Carcinoma Progression (2001) (83)
- The addition of mycophenolate mofetil to antiretroviral therapy including abacavir is associated with depletion of intracellular deoxyguanosine triphosphate and a decrease in plasma HIV-1 RNA. (2002) (83)
- International Federation of Clinical Chemistry/International Association of Therapeutic Drug Monitoring and Clinical Toxicology Working Group on Immunosuppressive Drug Monitoring (2002) (81)
- Advances in cyclosporine pharmacology, measurement, and therapeutic monitoring. (1989) (81)
- Biomarker discovery for Alzheimer’s disease, frontotemporal lobar degeneration, and Parkinson’s disease (2010) (81)
- The underreporting of cocaine-related trauma: drug abuse warning network reports vs hospital toxicology tests. (1993) (81)
- Pharmacokinetics of WR-2721. (1988) (81)
- Decreased protein binding of mycophenolic acid associated with leukopenia in a pancreas transplant recipient with renal failure. (1998) (80)
- Macrophage interactions with laminin: PMA selectively induces the adherence and spreading of mouse macrophages on a laminin substratum (1988) (79)
- Elevated CSF GAP-43 is Alzheimer’s disease specific and associated with tau and amyloid pathology (2018) (78)
- HPLC-atmospheric pressure chemical ionization MS/MS for quantification of 15-F2t-isoprostane in human urine and plasma. (2007) (76)
- Longitudinal Analyses of Cerebrospinal Fluid α-Synuclein in Prodromal and Early Parkinson’s Disease (2019) (76)
- Regulation of cellular interactions with laminin by integrin cytoplasmic domains: the A and B structural variants of the alpha 6 beta 1 integrin differentially modulate the adhesive strength, morphology, and migration of macrophages. (1994) (76)
- Pharmacokinetic role of protein binding of mycophenolic acid and its glucuronide metabolite in renal transplant recipients (2009) (73)
- The Alzheimer’s Disease Neuroimaging Initiative 2 Biomarker Core: A review of progress and plans (2015) (72)
- Sex and APOE ε4 genotype modify the Alzheimer’s disease serum metabolome (2020) (71)
- Isolation of gamma-glutamyltransferase from human liver, and comparison with the enzyme from human kidney. (1978) (71)
- Clinical and dopamine transporter imaging characteristics of non-manifest LRRK2 and GBA mutation carriers in the Parkinson's Progression Markers Initiative (PPMI): a cross-sectional study (2020) (71)
- Cerebrospinal fluid abnormalities and rate of decline in everyday function across the dementia spectrum: normal aging, mild cognitive impairment, and Alzheimer disease. (2010) (70)
- Robust Identification of Alzheimer’s Disease subtypes based on cortical atrophy patterns (2017) (69)
- Amifostine (WR-2721) shortens the engraftment period of 4-hydroperoxycyclophosphamide-purged bone marrow in breast cancer patients receiving high-dose chemotherapy with autologous bone marrow support. (1994) (67)
- Fimbrin localized to an insoluble cytoskeletal fraction is constitutively phosphorylated on its headpiece domain in adherent macrophages. (1993) (65)
- Pharmacokinetics of amifostine: effects of dose and method of administration. (1999) (65)
- Bypassing the first-pass effect for the therapeutic use of cannabinoids (1993) (64)
- Regulation of alpha 6 beta 1 integrin laminin receptor function by the cytoplasmic domain of the alpha 6 subunit (1993) (64)
- Can WR-2721 be improved upon? (1988) (64)
- Integrin Function in Breast Carcinoma Progression (1999) (63)
- CSF Apo-E levels associate with cognitive decline and MRI changes (2014) (63)
- Emerging β-amyloid pathology and accelerated cortical atrophy. (2014) (63)
- Pharmacokinetics of ganciclovir after oral valganciclovir versus intravenous ganciclovir in allogeneic stem cell transplant patients with graft-versus-host disease of the gastrointestinal tract. (2006) (63)
- International Federation of Clinical Chemistry, (IFCC), Scientific Committee, Analytical Section. IFCC methods for the measurement of catalytic concentration of enzymes. Part 4. IFCC method for gamma-glutamyltransferase [(gamma-glutamyl)-peptide: amino acid gamma-glutamyltransferase, EC 2.3.2.2]. (1983) (63)
- Fluid biomarkers in multiple system atrophy: A review of the MSA Biomarker Initiative (2015) (62)
- Comparison of xMAP and ELISA assays for detecting cerebrospinal fluid biomarkers of Alzheimer's disease. (2012) (62)
- Selenium detoxification is required for cancer cell survival (2020) (61)
- Metabolic pathways of WR-2721 (ethyol, amifostine) in the BALB/c mouse. (1994) (61)
- Beclin 1 regulates growth factor receptor signaling in breast cancer (2014) (60)
- Role of Insulin Receptor Substrates and Protein Kinase C-ζ in Vascular Permeability Factor/Vascular Endothelial Growth Factor Expression in Pancreatic Cancer Cells* (2004) (60)
- Mycophenolic Acid: Measurement and Relationship to Pharmacologie Effects (1995) (60)
- Toxic effects of immunosuppressive drugs: mechanisms and strategies for controlling them. (1996) (60)
- Targeted neurogenesis pathway-based gene analysis identifies ADORA2A associated with hippocampal volume in mild cognitive impairment and Alzheimer's disease (2017) (60)
- Cerebrospinal fluid tau, Aβ, and sTREM2 in Former National Football League Players: Modeling the relationship between repetitive head impacts, microglial activation, and neurodegeneration (2018) (60)
- Longitudinal plasma amyloid beta as a biomarker of Alzheimer’s disease (2012) (59)
- CSF progranulin increases in the course of Alzheimer's disease and is associated with sTREM2, neurodegeneration and cognitive decline (2018) (59)
- CSF tau and β-amyloid predict cerebral synucleinopathy in autopsied Lewy body disorders (2018) (59)
- GLI1 regulates a novel neuropilin-2/alpha6beta1 integrin based autocrine pathway that contributes to breast cancer initiation (2014) (58)
- Longitudinal measurement and hierarchical classification framework for the prediction of Alzheimer’s disease (2017) (58)
- An age-dependent pharmacokinetic study of intravenous and oral mycophenolate mofetil in combination with tacrolimus for GVHD prophylaxis in pediatric allogeneic stem cell transplantation recipients. (2010) (58)
- CSF protein biomarkers predicting longitudinal reduction of CSF β-amyloid42 in cognitively healthy elders (2013) (57)
- Ventricular maps in 804 ADNI subjects: correlations with CSF biomarkers and clinical decline (2010) (57)
- Identifying Neuroimaging and Proteomic Biomarkers for MCI and AD via the Elastic Net (2011) (57)
- New approaches to cyclosporine monitoring raise further concerns about analytical techniques. (2000) (56)
- Challenges and Opportunities with Causal Discovery Algorithms: Application to Alzheimer’s Pathophysiology (2020) (56)
- Analysis, pharmacokinetics and therapeutic drug monitoring of mycophenolic acid. (1998) (55)
- Genome-wide, high-content siRNA screening identifies the Alzheimer’s genetic risk factor FERMT2 as a major modulator of APP metabolism (2016) (55)
- Effects of traumatic brain injury and posttraumatic stress disorder on Alzheimer’s disease in veterans, using the Alzheimer’s Disease Neuroimaging Initiative (2014) (55)
- PENN Biomarker Core of the Alzheimer’s Disease Neuroimaging Initiative (2007) (55)
- Assessing the commutability of reference material formats for the harmonization of amyloid-β measurements (2016) (54)
- Low plasma leptin in cognitively impaired ADNI subjects: gender differences and diagnostic and therapeutic potential. (2014) (54)
- A key tyrosine (Y1494) in the beta4 integrin regulates multiple signaling pathways important for tumor development and progression. (2008) (54)
- Colchicine poisoning: report of a fatal case with body fluid analysis by GC/MS and histopathologic examination of postmortem tissues. (1991) (54)
- Influence of Genetic Variation on Plasma Protein Levels in Older Adults Using a Multi-Analyte Panel (2013) (54)
- Effect of mycophenolic acid glucuronide on inosine monophosphate dehydrogenase activity. (1997) (54)
- Plasma biomarkers of depressive symptoms in older adults (2012) (53)
- Intrinsic Signaling Functions of the β4 Integrin Intracellular Domain* (2007) (53)
- Association of plasma C-reactive protein levels with the diagnosis of Alzheimer's disease (2013) (53)
- Higher CSF sTREM2 and microglia activation are associated with slower rates of beta‐amyloid accumulation (2020) (52)
- Monitoring of Mycophenolic Acid in Clinical Transplantation (2002) (52)
- Plasma neuronal exosomal levels of Alzheimer's disease biomarkers in normal aging (2016) (52)
- A 2-Step Cerebrospinal Algorithm for the Selection of Frontotemporal Lobar Degeneration Subtypes (2018) (51)
- Sex differences in the genetic predictors of Alzheimer's pathology. (2019) (51)
- Using Established Immunosuppressant Therapy Effectively: Lessons from the Measurement of Mycophenolic Acid Plasma Concentrations (2004) (50)
- Cyclosporine bioavailability in heart-lung transplant candidates with cystic fibrosis. (1990) (50)
- Elecsys® Total-Tau and Phospho-Tau (181P) CSF assays: Analytical performance of the novel, fully automated immunoassays for quantification of tau proteins in human cerebrospinal fluid. (2019) (50)
- The Effect of Propofol Versus Isoflurane Anesthesia on Human Cerebrospinal Fluid Markers of Alzheimer's Disease: Results of a Randomized Trial. (2016) (50)
- SHP2 Mediates the Localized Activation of Fyn Downstream of the α6β4 Integrin To Promote Carcinoma Invasion (2010) (49)
- Interferon gamma and lipopolysaccharide promote macrophage adherence to basement membrane glycoproteins (1989) (49)
- Body mass index is associated with biological CSF markers of core brain pathology of Alzheimer's disease (2012) (47)
- Coacaethylene levels in patients who test positive for cocaine. (1996) (47)
- Profiling the dynamics of CSF and plasma Aβ reduction after treatment with JNJ-54861911, a potent oral BACE inhibitor (2016) (47)
- Review of the newest HPLC methods with mass spectrometry detection for determination of immunosuppressive drugs in clinical practice. (2009) (46)
- Round robin test on quantification of amyloid-β 1–42 in cerebrospinal fluid by mass spectrometry (2016) (46)
- Pharmacokinetic profile of amifostine. (1996) (46)
- Phosphorylated tau/amyloid beta 1-42 ratio in ventricular cerebrospinal fluid reflects outcome in idiopathic normal pressure hydrocephalus (2012) (46)
- Insulin Receptor Substrate-2 Regulates Aerobic Glycolysis in Mouse Mammary Tumor Cells via Glucose Transporter 1* (2009) (46)
- Cocaine and its metabolites constrict cerebral arterioles in newborn pigs. (1993) (46)
- Derivation of cutoffs for the Elecsys® amyloid β (1–42) assay in Alzheimer's disease (2018) (45)
- Effects of cerebrospinal fluid proteins on brain atrophy rates in cognitively healthy older adults (2014) (45)
- Anticholinergic toxicity associated with lupine seeds as a home remedy for diabetes mellitus. (1999) (45)
- New Dosing Regimens for Amifostine: A Pilot Study to Compare the Relative Bioavailability of Oral and Subcutaneous Administration with Intravenous Infusion (2002) (45)
- The transitional association between β-amyloid pathology and regional brain atrophy (2014) (44)
- Immunochemical evaluation of the organ specificity of prostatic acid phosphatase. (1981) (43)
- A pilot study of topical intrarectal application of amifostine for prevention of late radiation rectal injury. (2002) (43)
- Relationship of steady-state serum concentrations of amiodarone and desethylamiodarone to therapeutic efficacy and adverse effects. (1987) (43)
- Sensitive, High Throughput HPLC-MS/MS Method With On-line Sample Clean-up for Everolimus Measurement (2006) (43)
- Insulin Receptor Substrate 2-mediated Phosphatidylinositol 3-kinase Signaling Selectively Inhibits Glycogen Synthase Kinase 3β to Regulate Aerobic Glycolysis* (2014) (43)
- Hypoxia regulates insulin receptor substrate-2 expression to promote breast carcinoma cell survival and invasion. (2009) (43)
- IOP1, a novel hydrogenase-like protein that modulates hypoxia-inducible factor-1alpha activity. (2007) (43)
- Racial Disparity in Cerebrospinal Fluid Amyloid and Tau Biomarkers and Associated Cutoffs for Mild Cognitive Impairment (2019) (43)
- The impact of P-glycoprotein and Mrp2 on mycophenolic acid levels in mice. (2008) (42)
- Cerebrospinal fluid markers including trefoil factor 3 are associated with neurodegeneration in amyloid-positive individuals (2014) (42)
- Development, validation and application of a new fornix template for studies of aging and preclinical Alzheimer's disease (2016) (42)
- Gamma-Glutamyltransferase: kinetic properties and assay conditions when gamma-glutamyl-4-nitroanilide and its 3-carboxy derivative are used as donor substrates. (1977) (41)
- Therapeutic drug monitoring of cyclosporine and tacrolimus. Update on Lake Louise Consensus Conference on cyclosporin and tacrolimus. (1998) (40)
- Pharmacokinetic Modelling of the Plasma Protein Binding of Mycophenolic Acid in Renal Transplant Recipients (2009) (40)
- Relationship between Plasma Analytes and SPARE-AD Defined Brain Atrophy Patterns in ADNI (2013) (40)
- ApoE4 effects on automated diagnostic classifiers for mild cognitive impairment and Alzheimer's disease (2014) (40)
- Validation of the Erlangen Score Algorithm for the Prediction of the Development of Dementia due to Alzheimer's Disease in Pre-Dementia Subjects. (2015) (40)
- Sex-specific genetic predictors of Alzheimer’s disease biomarkers (2018) (40)
- Cerebrospinal fluid analyses for the diagnosis of subarachnoid haemorrhage and experience from a Swedish study. What method is preferable when diagnosing a subarachnoid haemorrhage? (2013) (39)
- Treatment of hypercalcemia in parathyroid cancer with WR-2721, S-2-(3-aminopropylamino)ethyl-phosphorothioic acid. (1985) (39)
- Brain amyloidosis ascertainment from cognitive, imaging, and peripheral blood protein measures (2015) (39)
- Prospective investigations of concentration-clinical response for immunosuppressive drugs provide the scientific basis for therapeutic drug monitoring. (1998) (38)
- Biomarkers in frontotemporal lobar degenerations—Progress and challenges (2011) (38)
- A Liquid Chromatographic Electrochemical Assay for S-2-(3-Aminopropylamino) Ethylphosphorothioate (WR2721) in Human Plasma (1984) (38)
- Clinical and Dopamine Transporter Imaging Characteristics of Leucine Rich Repeat Kinase 2 (LRRK2) and Glucosylceramidase Beta (GBA) Parkinson's Disease Participants in the Parkinson's Progression Markers Initiative: A Cross‐Sectional Study (2020) (38)
- Hydrolysis of WR2721 by mouse liver cell fractions. (1987) (38)
- Measurements of auto‐antibodies to α‐synuclein in the serum and cerebral spinal fluids of patients with Parkinson's disease (2018) (37)
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- 158 A PHARMACOKINETIC STUDY OF PACLITAXEL IN PATIENTS WITH METASTATIC COLORECTAL CANCER (1995) (0)
- Measurement of plasma gamma glutamyl transferases activities and standardization (1981) (0)
- The Role of Integrin Signaling in Breast Cancer. (1997) (0)
- Abstract 3291: Upregulation of Insulin Receptor Substrate-2 (IRS-2) expression by hypoxia (2010) (0)
- 76 MYCOPHENOLIC ACID BINDING TO PLASMA PROTEINS MODULATES ITS PHARMACOLOGIC ACTIVITY (1995) (0)
- Featured Article Round robin test on quantification of amyloid-b 1-42 in cerebrospinal fluid by mass spectrometry (2016) (0)
- Predictive Performance of CSF Biomarkers for Conversion from Mild Cognitive Impairment to Alzheimer's Disease (2012) (0)
- FV 3 Analysis of cerebrospinal fluid (CSF) biomarkers to predict risk of clinical decline and progression to dementia in patients with mild cognitive impairment and mild cognitive symptoms (2019) (0)
- Comparative Clinical Bioavailability of Delta-9-THC from a Suppository Formulation Containing the Hemisuccinate Ester vs. an Oral Preparation (1993) (0)
- Effect of Dopamine Antagonism on Tissue Blood Flow Response to Cocaine (1994) (0)
- Regulation of Breast Carcinoma Progresssion by the Integrins. (1998) (0)
- MPA protein Binding in Uremic Plasma: Prediction of Free Fraction (1999) (0)
- ANALYSIS OF PROTEIN-BOUND AND TOTAL S-2-(3-AMINOPROPYLAMINO)ETHANETHIOL (WR-1065) IN BLOOD BY HIGH PERFORMANCE LIQUID CHROMATOGRAPHY (HPLC). (1999) (0)
- Optimal alpha-oxobutyrate concentration for assay of alpha-hydroxybutyrate dehydrogenase activity in normal and pathological sera at 30 degrees C. (1974) (0)
- Web‐based requisitioning, tracking and laboratory result reporting system for clinical trials using a central laboratory (2020) (0)
- COMPARISON OF FLORTAUCIPIR PET WITH CEREBROSPINAL FLUID, COGNITIVE FUNCTIONING AND NEUROIMAGING MEASURES IN MILD COGNITIVE IMPAIRMENT DUE TO ALZHEIMER’S DISEASE (2019) (0)
- Pharmacokinetics (PK) of Mycophenolate Mofetil (MMF) in Pediatric Allogeneic Stem Cell Transplant (AlloSCT) Recipients Are Associated with Significantly Higher Clearance. (2005) (0)
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What Schools Are Affiliated With Leslie Michael Shaw?
Leslie Michael Shaw is affiliated with the following schools: