Lester Kobzik
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Researcher ORCID ID = 0000-0003-4328-937X
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Biomedical Engineering
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Engineering
Lester Kobzik's Degrees
- PhD Biomedical Engineering University of California, Berkeley
- Masters Biomedical Engineering Stanford University
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(Suggest an Edit or Addition)Lester Kobzik's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Nitric oxide in skeletal muscle (1994) (1006)
- An experimental model of idiopathic pneumonia syndrome after bone marrow transplantation: I. The roles of minor H antigens and endotoxin. (1996) (917)
- Nitric oxide synthase in human and rat lung: immunocytochemical and histochemical localization. (1993) (846)
- Toll4 (TLR4) expression in cardiac myocytes in normal and failing myocardium. (1999) (665)
- Reduced Myocardial Ischemia-Reperfusion Injury in Toll-Like Receptor 4-Deficient Mice (2003) (637)
- Endothelial Nitric Oxide Synthase Targeting to Caveolae (1996) (532)
- Reactive oxygen in skeletal muscle. I. Intracellular oxidant kinetics and fatigue in vitro. (1992) (506)
- Abnormal contractile function due to induction of nitric oxide synthesis in rat cardiac myocytes follows exposure to activated macrophage-conditioned medium. (1993) (478)
- MicroRNA-181b regulates NF-κB-mediated vascular inflammation. (2012) (462)
- Ipr1 gene mediates innate immunity to tuberculosis (2005) (443)
- Nitric Oxide-dependent Parasympathetic Signaling Is Due to Activation of Constitutive Endothelial (Type III) Nitric Oxide Synthase in Cardiac Myocytes (*) (1995) (420)
- Hypoxia induces severe right ventricular dilatation and infarction in heme oxygenase-1 null mice. (1999) (418)
- Endothelial type nitric oxide synthase in skeletal muscle fibers: mitochondrial relationships. (1995) (408)
- Reperfusion injury of ischemic skeletal muscle is mediated by natural antibody and complement (1996) (407)
- The negative inotropic effect of beta3-adrenoceptor stimulation is mediated by activation of a nitric oxide synthase pathway in human ventricle. (1998) (391)
- Reciprocal Rb inactivation and p16INK4 expression in primary lung cancers and cell lines. (1995) (377)
- The Scavenger Receptor MARCO Is Required for Lung Defense against Pneumococcal Pneumonia and Inhaled Particles (2004) (363)
- Reactive oxygen species in pulmonary inflammation by ambient particulates. (2003) (349)
- Upregulation of &bgr;3-Adrenoceptors and Altered Contractile Response to Inotropic Amines in Human Failing Myocardium (2001) (291)
- Intestinal reperfusion injury is mediated by IgM and complement. (1999) (274)
- Functional characterization of the rat chemokine KC and its importance in neutrophil recruitment in a rat model of pulmonary inflammation. (1995) (274)
- Role of the Scavenger Receptor MARCO in Alveolar Macrophage Binding of Unopsonized Environmental Particles (1999) (253)
- Neutrophil and Nonneutrophil‐Mediated Injury in Intestinal Ischemia‐Reperfusion (1993) (247)
- A Consensus Definitive Classification of Scavenger Receptors and Their Roles in Health and Disease (2017) (218)
- Contribution of Nitric Oxide Synthases 1, 2, and 3 to Airway Hyperresponsiveness and Inflammation in a Murine Model of Asthma (1999) (216)
- Postischemic renal injury is mediated by neutrophils and leukotrienes. (1989) (214)
- MARCO Is the Major Binding Receptor for Unopsonized Particles and Bacteria on Human Alveolar Macrophages1 (2005) (211)
- Mac-1 (CD11b/CD18) and the urokinase receptor (CD87) form a functional unit on monocytic cells. (1996) (196)
- Expression of macrophage inflammatory protein-2 and KC mRNA in pulmonary inflammation. (1992) (194)
- Elevated nitric oxide concentrations in isolated lower airway gas of asthmatic subjects. (1996) (194)
- Risk for Asthma in Offspring of Asthmatic Mothers versus Fathers: A Meta-Analysis (2010) (192)
- Pulmonary exposure to particles during pregnancy causes increased neonatal asthma susceptibility. (2008) (176)
- Lung macrophage uptake of unopsonized environmental particulates. Role of scavenger-type receptors. (1995) (167)
- The macrophage scavenger receptor SR-AI/II and lung defense against pneumococci and particles. (2006) (166)
- Standardizing Scavenger Receptor Nomenclature (2014) (165)
- Suppression of Herpes Simplex Virus Type 1 (HSV-1)–induced Pneumonia in Mice by Inhibition of Inducible Nitric Oxide Synthase (iNOS, NOS2) (1997) (160)
- Analysis of air pollution particulate-mediated oxidant stress in alveolar macrophages. (1998) (155)
- Characterization of murine lung interstitial macrophages in comparison with alveolar macrophages in vitro. (1996) (151)
- Inhibition of T cell costimulation abrogates airway hyperresponsiveness in a murine model. (1996) (150)
- Scavenger receptor class‐A is a novel cell surface receptor for double‐stranded RNA (2008) (149)
- Targeted deletion of caspase-1 reduces early mortality and left ventricular dilatation following myocardial infarction. (2003) (149)
- A pilot investigation of the relative toxicity of indoor and outdoor fine particles: in vitro effects of endotoxin and other particulate properties. (2001) (147)
- Insoluble components of concentrated air particles mediate alveolar macrophage responses in vitro. (2000) (142)
- Nitric oxide synthase (NOS3)-mediated cholinergic modulation of Ca2+ current in adult rabbit atrioventricular nodal cells. (1996) (141)
- Host reactive donor T cells are associated with lung injury after experimental allogeneic bone marrow transplantation. (1998) (141)
- Depletion of alveolar macrophages decreases neutrophil chemotaxis to Pseudomonas airspace infections. (1996) (139)
- NF-kappa B/Rel transcription factors: c-Rel promotes airway hyperresponsiveness and allergic pulmonary inflammation. (1999) (136)
- Lower torso ischemia-induced lung injury is leukocyte dependent. (1988) (135)
- Tumor necrosis factor-alpha neutralization reduces lung injury after experimental allogeneic bone marrow transplantation. (2000) (132)
- Induction of Nitric Oxide Synthase Activity by Cytokines in Ventricular Myocytes Is Necessary but Not Sufficient to Decrease Contractile Responsiveness to β-Adrenergic Agonists (1995) (129)
- Protection against inhaled oxidants through scavenging of oxidized lipids by macrophage receptors MARCO and SR-AI/II. (2007) (128)
- Environmental particulate-mediated cytokine production in lung epithelial cells (A549): role of preexisting inflammation and oxidant stress. (1998) (126)
- Lung macrophage-epithelial cell interactions amplify particle-mediated cytokine release. (2002) (120)
- Dominant role of the sst1 locus in pathogenesis of necrotizing lung granulomas during chronic tuberculosis infection and reactivation in genetically resistant hosts. (2009) (118)
- Disparate Regulation and Function of the Class A Scavenger Receptors SR-AI/II and MARCO1 (2005) (116)
- TNF Drives Monocyte Dysfunction with Age and Results in Impaired Anti-pneumococcal Immunity (2016) (115)
- Allergen-Independent Maternal Transmission of Asthma Susceptibility 1 (2003) (114)
- Receptors for unopsonized particles: the role of alveolar macrophage scavenger receptors. (2001) (110)
- Oxidative Metabolism in the Alveolar Macrophage: Analysis by Flow Cytometry (1990) (107)
- Effect of concentrated ambient particles on macrophage phagocytosis and killing of Streptococcus pneumoniae. (2007) (107)
- Induction of NO synthase in rat cardiac microvascular endothelial cells by IL-1 beta and IFN-gamma. (1995) (105)
- Role for tumor necrosis factor as mediator of lung injury following lower torso ischemia. (1991) (104)
- Oxygen free radicals mediate ischemia-induced lung injury. (1989) (102)
- Functional Activity of Natural Antibody is Altered in Cr2-Deficient Mice1 (2002) (101)
- Lung epithelial cell (A549) interaction with unopsonized environmental particulates: quantitation of particle-specific binding and IL-8 production. (1996) (96)
- Tumor Necrosis Factor-α Mediates Acid Aspiration-induced Systemic Organ Injury (1990) (96)
- Air pollution particles diminish bacterial clearance in the primed lungs of mice. (2007) (91)
- Contractile responsiveness of ventricular myocytes to isoproterenol is regulated by induction of nitric oxide synthase activity in cardiac microvascular endothelial cells in heterotypic primary culture. (1995) (90)
- Stromelysin-3 is overexpressed by stromal elements in primary non-small cell lung cancers and regulated by retinoic acid in pulmonary fibroblasts. (1995) (88)
- Targeted deletion of nrf2 impairs lung development and oxidant injury in neonatal mice. (2012) (88)
- The Class A Scavenger Receptor, Macrophage Receptor with Collagenous Structure, Is the Major Phagocytic Receptor for Clostridium sordellii Expressed by Human Decidual Macrophages (2010) (88)
- Role of plasminogen activator in degradation of extracellular matrix protein by live human alveolar macrophages. (1988) (86)
- Alternative activation of macrophages and pulmonary fibrosis are modulated by scavenger receptor, macrophage receptor with collagenous structure (2015) (84)
- Role of scavenger receptor MARCO in macrophage responses to CpG oligodeoxynucleotides (2006) (84)
- Lipopolysaccharide priming amplifies lung macrophage tumor necrosis factor production in response to air particles. (1999) (82)
- Skeletal muscle reperfusion injury is mediated by neutrophils and the complement membrane attack complex. (1999) (82)
- Allergy risk is mediated by dendritic cells with congenital epigenetic changes. (2011) (82)
- Thromboxane mediates the ischemia-induced neutrophil oxidative burst. (1989) (81)
- IL-10-dependent Tr1 cells attenuate astrocyte activation and ameliorate chronic central nervous system inflammation (2016) (79)
- Nitric oxide modulates excitation-contraction coupling in the diaphragm. (1998) (79)
- A Chronic Obstructive Pulmonary Disease Susceptibility Gene, FAM13A, Regulates Protein Stability of β-Catenin. (2016) (79)
- Flow cytometric assay of lung macrophage uptake of environmental particulates. (1995) (79)
- Gene control of tyrosine kinase TIE2 and vascular manifestations of infections (2016) (78)
- Alveolar macrophage cytokine response to air pollution particles: oxidant mechanisms. (2007) (78)
- Alveolar macrophage cytokine production in response to air particles in vitro: role of endotoxin. (2000) (76)
- Alteration of pulmonary macrophage function by respiratory syncytial virus infection in vitro. (1995) (76)
- Hyporesponsiveness of Donor Cells to Lipopolysaccharide Stimulation Reduces the Severity of Experimental Idiopathic Pneumonia Syndrome: Potential Role for a Gut-Lung Axis of Inflammation1 (2000) (75)
- Prenatal Maternal Stress Predicts Childhood Asthma in Girls: Project Ice Storm (2014) (73)
- Differential expression of a gene signature for scavenger/lectin receptors by endothelial cells and macrophages in human lymph node sinuses, the primary sites of regional metastasis (2006) (72)
- Reactive oxygen species and elastase mediate lung permeability after acid aspiration. (1992) (71)
- Particle opsonization and lung macrophage cytokine response. In vitro and in vivo analysis. (1993) (70)
- Prostacyclin and thromboxane A2 moderate postischemic renal failure. (1985) (69)
- Pulmonary Leukosequestration Induced by Hind Limb Ischemia (1987) (69)
- Alveolar macrophage interaction with air pollution particulates. (1997) (69)
- Pulmonary hypertension and leukosequestration after lower torso ischemia. (1987) (68)
- Rat KC cDNA cloning and mRNA expression in lung macrophages and fibroblasts. (1992) (68)
- Nuclear factor-kappaB p50 limits inflammation and prevents lung injury during Escherichia coli pneumonia. (2003) (67)
- Exposure of Pregnant Mice to an Air Pollutant Aerosol Increases Asthma Susceptibility in Offspring (2007) (67)
- Selective down-regulation of alveolar macrophage oxidative response to opsonin-independent phagocytosis. (1990) (67)
- α1-Acid glycoprotein reduces local and remote injuries after intestinal ischemia in the rat. (1997) (66)
- Surfactant Protein A (SP-A)-mediated Clearance of Staphylococcus aureus Involves Binding of SP-A to the Staphylococcal Adhesin Eap and the Macrophage Receptors SP-A Receptor 210 and Scavenger Receptor Class A* (2010) (66)
- Intestinal ischemia-reperfusion injury is mediated by the membrane attack complex. (1999) (66)
- Resistance of very young mice to inhaled allergen sensitization is overcome by coexposure to an air-pollutant aerosol. (2000) (66)
- Differential expression of a gene signature for scavenger/lectin receptors by endothelial cells and macrophages in human lymph node sinuses, the primary sites of regional metastasis. (2006) (66)
- In Vitro Efficacy of Morpholino-modified Antisense Oligomers Directed against Tumor Necrosis Factor-α mRNA* (1996) (65)
- Scavenger Receptors SR-AI/II and MARCO Limit Pulmonary Dendritic Cell Migration and Allergic Airway Inflammation1 (2007) (64)
- Contribution of type I NOS to expired gas NO and bronchial responsiveness in mice. (1997) (64)
- TRIF Mediates Toll-Like Receptor 2-Dependent Inflammatory Responses to Borrelia burgdorferi (2012) (63)
- Increased airway responsiveness to inhaled methacholine in a rat model of chronic bronchitis. (1995) (63)
- Induction of NO synthase in rat cardiac microvascular endothelial cells by IL-1β and IFN-γ (1995) (62)
- The Role of Complement and Natural Antibody in Intestinal Ischemia-Reperfusion Injury (2003) (62)
- Tracking translocation of industrially relevant engineered nanomaterials (ENMs) across alveolar epithelial monolayers in vitro (2014) (62)
- Stromelysin-3 Is Induced in Tumor/Stroma Cocultures and Inactivated via a Tumor-specific and Basic Fibroblast Growth Factor-dependent Mechanism* (1998) (62)
- Signaling pathways required for macrophage scavenger receptor-mediated phagocytosis: analysis by scanning cytometry (2008) (62)
- Scavenger receptor A mediates H2O2 production and suppression of IL‐12 release in murine macrophages (2004) (61)
- Profibrotic Activities for Matrix Metalloproteinase-8 during Bleomycin-Mediated Lung Injury (2013) (61)
- T cell activation in a murine model of asthma. (1996) (61)
- S-nitrosothiols inhibit neuronal norepinephrine transport. (1997) (61)
- CD23 and allergic pulmonary inflammation: potential role as an inhibitor. (1999) (61)
- Synergism between leukotriene B4 and thromboxane A2 in mediating acid-aspiration injury. (1992) (60)
- Effects of Laser Printer–Emitted Engineered Nanoparticles on Cytotoxicity, Chemokine Expression, Reactive Oxygen Species, DNA Methylation, and DNA Damage: A Comprehensive in Vitro Analysis in Human Small Airway Epithelial Cells, Macrophages, and Lymphoblasts (2015) (59)
- MARCO regulates early inflammatory responses against influenza: a useful macrophage function with adverse outcome. (2011) (58)
- Recombinant granulocyte-macrophage colony-stimulating factor down-regulates expression of IL-2 receptor on human mononuclear phagocytes by induction of prostaglandin E. (1988) (58)
- Inhibition of sphincter of Oddi function by the nitric oxide carrier S-nitroso-N-acetylcysteine in rabbits and humans. (1994) (58)
- Thromboxane A2 Mediates Increased Pulmonary Microvascular Permeability Following Limb Ischemia (1989) (58)
- Mast cells and leukotrienes mediate neutrophil sequestration and lung edema after remote ischemia in rodents. (1992) (57)
- In the absence of T cells, natural killer cells protect from mortality due to HSV-1 encephalitis (1999) (56)
- Both CD80 and CD86 co-stimulatory molecules regulate allergic pulmonary inflammation. (1998) (56)
- Substance P-induced histamine release in tracheally perfused guinea pig lungs. (1995) (56)
- B7-1 (CD80) and B7-2 (CD86) have complementary roles in mediating allergic pulmonary inflammation and airway hyperresponsiveness. (2000) (56)
- Airway neutrophilia and chemokine mRNA expression in sulfur dioxide-induced bronchitis. (1995) (56)
- Effects of chronic airway inflammation on the activity and enzymatic inactivation of neuropeptides in guinea pig lungs. (1994) (54)
- GM-CSF modulates pulmonary resistance to influenza A infection. (2011) (54)
- A Role for Tumor Necrosis Factor-&agr;-Mediated Endothelial Apoptosis in the Development of Experimental Idiopathic Pneumonia Syndrome (2004) (54)
- Experimental murine acid aspiration injury is mediated by neutrophils and the alternative complement pathway. (1997) (53)
- Progression of Pulmonary Tuberculosis and Efficiency of Bacillus Calmette-Guérin Vaccination Are Genetically Controlled via a Common sst1-Mediated Mechanism of Innate Immunity1 (2007) (52)
- Expression of nitric oxide synthase-2 in the lungs decreases airway resistance and responsiveness. (2004) (50)
- Exposures and Cross-shift Lung Function Declines in Wildland Firefighters (2014) (50)
- Female resistance to pneumonia identifies lung macrophage nitric oxide synthase-3 as a therapeutic target (2014) (50)
- Leukotrienes but not Complement Mediate Limb Ischemia‐Induced Lung Injury (1989) (49)
- Role of Breast Milk in a Mouse Model of Maternal Transmission of Asthma Susceptibility1 (2006) (49)
- Pulmonary veno-occlusive disease in pulmonary Langerhans' cell granulomatosis. (2000) (48)
- REVIEW ARTICLE: Maternal Transmission of Asthma Risk (2008) (48)
- Characteristics of nitric oxide‐mediated cholinergic modulation of calcium current in rabbit sino‐atrial node (1998) (48)
- Detection of lymphokines and lymphokine receptors in pulmonary sarcoidosis. Immunohistologic evidence that inflammatory macrophages express IL-2 receptors. (1986) (47)
- Role of neutrophil adherence receptors (CD 18) in lung permeability following lower torso ischemia. (1992) (47)
- Surveillance transbronchial lung biopsies: implication for survival after lung transplantation. (2000) (47)
- Specific transcriptional enhancement of inducible nitric oxide synthase by targeted promoter demethylation (2013) (47)
- Vasodilating Prostaglandins Attenuate Ischemic Renal Injury Only if Thromboxane is Inhibited (1989) (46)
- Neutrophil adherence receptors (CD 18) in ischemia. Dissociation between quantitative cell surface expression and diapedesis mediated by leukotriene B4. (1990) (45)
- Maternal stress during pregnancy increases neonatal allergy susceptibility: role of glucocorticoids. (2014) (45)
- Rapamycin treatment depresses intragraft expression of KC/MIP-2, granzyme B, and IFN-gamma in rat recipients of cardiac allografts. (1993) (45)
- Functional characterization of rat chemokine macrophage inflammatory protein-2 (1995) (45)
- Vasodilator prostaglandins (PG) prevent renal damage after ischemia. (1987) (45)
- Leukocytes mediate acid aspiration-induced multiorgan edema. (1993) (45)
- Increased airway hyperresponsiveness and inflammation in a juvenile mouse model of asthma exposed to air-pollutant aerosol. (1999) (45)
- Arterial stiffness, oxidative stress, and smoke exposure in wildland firefighters. (2014) (44)
- Role of Macrophage Receptor with Collagenous Structure in Innate Immune Tolerance (2013) (44)
- Pivotal Advance: Expansion of small sputum macrophages in CF: failure to express MARCO and mannose receptors (2009) (44)
- HSV-1 exploits the innate immune scavenger receptor MARCO to enhance epithelial adsorption and infection (2013) (44)
- Moderation of skeletal muscle reperfusion injury by a sLe(x)-glycosylated complement inhibitory protein. (2001) (44)
- Interleukin‐2 Induces Early Multisystem Organ Edema Mediated by Neutrophils (1991) (43)
- IN VITRO MODELING OF HUMAN ALVEOLAR MACROPHAGE SMOKE EXPOSURE: ENHANCED INFLAMMATION AND IMPAIRED FUNCTION (2008) (43)
- Adoptively transferred allergen-specific T cells cause maternal transmission of asthma risk. (2006) (42)
- Fluorescence-based measurement of nitric oxide synthase activity in activated rat macrophages using dichlorofluorescin. (1997) (42)
- Scavenger receptors and β-glucan receptors participate in the recognition of yeasts by murine macrophages (2011) (41)
- Sodium channel mutation leading to saxitoxin resistance in clams increases risk of PSP (2010) (41)
- Transgenerational transmission of asthma risk after exposure to environmental particles during pregnancy. (2017) (41)
- Plasma gelsolin improves lung host defense against pneumonia by enhancing macrophage NOS3 function. (2015) (41)
- Intracellular oxidant production and cytokine responses in lung macrophages: evaluation of fluorescent probes (1999) (40)
- A potent antiangiogenic factor, endostatin prevents the development of asthma in a murine model. (2005) (40)
- Future Research Directions in Pneumonia. NHLBI Working Group Report (2018) (40)
- Heterogeneity in Macrophage Phagocytosis of Staphylococcus aureus Strains: High-Throughput Scanning Cytometry-Based Analysis (2009) (39)
- Cyclic GMP is a second messenger by which nitric oxide inhibits diaphragm contraction. (1998) (39)
- alpha 1-Acid glycoprotein reduces local and remote injuries after intestinal ischemia in the rat. (1997) (39)
- Alveolar macrophage uptake of the environmental particulate titanium dioxide: role of surfactant components. (1996) (39)
- Inactivation of common hospital acquired pathogens on surfaces and in air utilizing engineered water nanostructures (EWNS) based nano-sanitizers. (2019) (37)
- Persistence of pulmonary pathology and abnormal lung function in IL-3/GM-CSF/IL-5 β c receptor-deficient mice despite correction of alveolar proteinosis after BMT (1997) (37)
- Isolation and antigenic identification of hamster lung interstitial macrophages. (1988) (36)
- Minimum protective serum concentrations of pneumococcal anti-capsular antibodies in infant rats. (1998) (35)
- Link between Epigenomic Alterations and Genome-Wide Aberrant Transcriptional Response to Allergen in Dendritic Cells Conveying Maternal Asthma Risk (2013) (35)
- Tumor necrosis factor-alpha mediates acid aspiration-induced systemic organ injury. (1990) (35)
- The Scavenger Receptor MARCO Modulates TLR-Induced Responses in Dendritic Cells (2014) (35)
- Effects of environmental aerosols on airway hyperresponsiveness in a murine model of asthma. (1999) (34)
- In vivo evaluation of a morpholino antisense oligomer directed against tumor necrosis factor-alpha. (2000) (34)
- Maternal allergic contact dermatitis causes increased asthma risk in offspring (2007) (34)
- Ischemia-induced neutrophil activation and diapedesis is lipoxygenase dependent. (1990) (34)
- Neutrophil accumulations due to pulmonary thromboxane synthesis mediate acid aspiration injury. (1991) (33)
- Immunostimulatory CpG Oligonucleotides Abrogate Allergic Susceptibility in a Murine Model of Maternal Asthma Transmission1 (2005) (33)
- Interleukin-2-induced lung injury is mediated by oxygen free radicals. (1991) (33)
- P-selectin mediates intestinal ischemic injury by enhancing complement deposition. (1996) (33)
- Lavage with leukotriene B4 induces lung generation of tumor necrosis factor-alpha that in turn mediates neutrophil diapedesis. (1993) (32)
- Peritonitis causes diaphragm weakness in rats. (1998) (32)
- Adam8 Limits the Development of Allergic Airway Inflammation in Mice (2013) (31)
- COMBINED AIR POLLUTION PARTICLE AND OZONE EXPOSURE INCREASES AIRWAY RESPONSIVENESS IN MICE (2002) (31)
- Characterization of immortalized MARCO and SR-AI/II-deficient murine alveolar macrophage cell lines (2008) (31)
- The distinction of mesothelioma from adenocarcinoma in malignant effusions by electron microscopy. (1985) (30)
- Defective pulmonary recruitment of neutrophils in a rat model of endotoxemia. (1994) (30)
- The effect of aerosolized recombinant human granulocyte macrophage colony-stimulating factor on lung leukocytes in nonhuman primates. (1992) (29)
- Influenza lung injury: mechanisms and therapeutic opportunities. (2015) (29)
- Alveolar macrophage-environmental particle interaction: analysis by flow cytometry. (2000) (28)
- Involvement of Thromboxane and Neutrophils in Multiple‐system Organ Edema with Interleukin‐2 (1990) (28)
- Effects of engineered nanomaterial exposure on macrophage innate immune function. (2016) (28)
- Duration of Allergic Susceptibility in Maternal Transmission of Asthma Risk (2007) (27)
- Development of a model of low-inoculum Streptococcus pneumoniae intrapulmonary infection in infant rats (1997) (27)
- Genome-Wide RNAi Screen in IFN-γ-Treated Human Macrophages Identifies Genes Mediating Resistance to the Intracellular Pathogen Francisella tularensis (2012) (27)
- The Rapid Induction by Interleukin‐2 of Pulmonary Microvascular Permeability (1989) (27)
- Comparison of efficacy of antisense oligomers directed toward TNF-alpha in helper T and macrophage cell lines. (1997) (27)
- Age-dependent regulation of SARS-CoV-2 cell entry genes and cell death programs correlates with COVID-19 severity (2021) (27)
- Targeting of CD25 and Glucocorticoid-Induced TNF Receptor Family-Related Gene-Expressing T Cells Differentially Modulates Asthma Risk in Offspring of Asthmatic and Normal Mother Mice1 (2007) (26)
- Inhibition of thromboxane (Tx) synthesis by free radical scavengers. (1988) (26)
- Translating NO biology into clinical advances: still searching for the right dictionary? (2009) (26)
- Ischemia activates neutrophils but inhibits their local and remote diapedesis. (1990) (26)
- Prenatal exposure to tobacco smoke sex dependently influences methylation and mRNA levels of the Igf axis in lungs of mouse offspring. (2017) (26)
- Soluble P-selectin moderates complement-dependent reperfusion injury of ischemic skeletal muscle. (2000) (25)
- Transplacental Passage of Interleukins 4 and 13? (2009) (24)
- Determinants of host susceptibility to murine respiratory syncytial virus (RSV) disease identify a role for the innate immunity scavenger receptor MARCO gene in human infants (2016) (24)
- Pulmonary and systemic consequences of localized acid aspiration. (1986) (24)
- Immunomodulators targeting MARCO expression improve resistance to postinfluenza bacterial pneumonia. (2017) (24)
- Flow cytometric analysis of macrophage oxidative metabolism using DCFH. (1998) (24)
- The detection of inflammation in collapsed lung by alterations in proton nuclear magnetic relaxation times. (1985) (23)
- A Role for Transforming Growth Factor-β1 in the Increased Pneumonitis in Murine Allogeneic Bone Marrow Transplant Recipients With Graft-Versus-Host Disease After Pulmonary Herpes Simplex Virus Type 1 Infection (1998) (23)
- Development of surface membrane characteristics of "premedullary" macrophages in organ cultures of embryonic rat and hamster lungs. (1989) (22)
- Induction of nitric oxide synthase activity by cytokines in ventricular myocytes is necessary but not sufficient to decrease contractile responsiveness to beta-adrenergic agonists. (1995) (22)
- Effects of sodium concentration on human neutrophil bactericidal functions. (1995) (22)
- Respiratory tract inflammation during the induction of chronic bronchitis in rats: role of C-fibres. (1999) (22)
- The structure and function of marco, a macrophage class a scavenger receptor. (2004) (22)
- Effect of TNF-alpha antisense oligomers on cytokine production by primary murine alveolar macrophages. (1998) (22)
- Nitric oxide regulation of atrioventricular node excitability. (1997) (21)
- Neutrophil adhesion receptor CD18 mediates remote but not localized acid aspiration injury. (1995) (21)
- Characterization of colony stimulating factor activity in the human respiratory tract. Comparison of healthy smokers and nonsmokers. (1992) (20)
- Macrophage FABP4 is required for neutrophil recruitment and bacterial clearance in Pseudomonas aeruginosa pneumonia (2018) (20)
- Free actin impairs macrophage bacterial defenses via scavenger receptor MARCO interaction with reversal by plasma gelsolin. (2017) (20)
- Serotype-dependent induction of pulmonary neutrophilia and inflammatory cytokine gene expression by reovirus (1996) (20)
- Contribution of type I NOS to expired gas NO and bronchial responsiveness in mice. (1997) (19)
- Human neutrophil elastase-mediated goblet cell metaplasia is attenuated in TACE-deficient mice. (2013) (19)
- Markers of Inflammation in Alveolar Cells Exposed to Fine Particulate Matter From Prescribed Fires and Urban Air (2011) (18)
- A high plasma prostaglandin to thromboxane ratio protects against renal ischemia. (1987) (18)
- Customized PCR-Array Analysis Informed by Gene-Chip Microarray and Biological Hypothesis Reveals Pathways Involved in Lung Inflammatory Response to Titanium Dioxide in Pregnancy (2010) (18)
- Particle-epithelial interaction: effect of priming and bystander neutrophils on interleukin-8 release. (2004) (18)
- Membrane attack complex of complement and neutrophils mediate the injury of acid aspiration. (1999) (18)
- AIRWAY HYPERRESPONSIVENESS CAUSED BY AEROSOL EXPOSURE TO RESIDUAL OIL FLY ASH LEACHATE IN MICE (2002) (18)
- Age-dependent regulation of SARS-CoV-2 cell entry genes and cell death programs correlates with COVID-19 disease severity (2020) (17)
- Adherent neutrophils mediate permeability after atelectasis. (1992) (17)
- Sexual tension in the airways: the puzzling duality of estrogen in asthma. (2008) (17)
- Attenuation of IL-2-induced multisystem organ edema by phalloidin and antamanide. (1991) (16)
- The fetal programming effect of prenatal smoking on Igf1r and Igf1 methylation is organ- and sex-specific (2017) (16)
- Immunohistologic analysis of a human pulmonary alveolar macrophage antigen. (1985) (16)
- NTRK1 is a positive regulator of YAP oncogenic function (2018) (16)
- Phagocytic Receptors Activate Syk and Src Signaling during Borrelia burgdorferi Phagocytosis (2017) (15)
- The integrated stress response mediates necrosis in murine Mycobacterium tuberculosis granulomas. (2020) (14)
- Demonstration of an idiotypic antigen on a monoclonal cold agglutinin and on its isolated heavy and light chains. (1976) (14)
- THE ROLES OF ALLOREACTIVITY AND ENDOTOXIN IN AN EXPERIMENTAL MODEL OF IDIOPATHIC PNEUMONIA SYNDROME AFTER BONE MARROW TRANSPLANTATION. • 909 (1996) (14)
- Fine-tuning of macrophage activation using synthetic rocaglate derivatives (2016) (13)
- A role for transforming growth factor-beta1 in the increased pneumonitis in murine allogeneic bone marrow transplant recipients with graft-versus-host disease after pulmonary herpes simplex virus type 1 infection. (1998) (13)
- Hindlimb ischemia-reperfusion increases complement deposition and glycolysis. (1999) (13)
- Sialyl Lewis(x) hybridized complement receptor type 1 moderates acid aspiration injury. (2001) (13)
- Monoclonal antibody to an alveolar macrophage surface antigen in hamsters. (1984) (13)
- Estrogen-mediated impairment of macrophageal uptake of environmental TiO2 particles to explain inflammatory effect of TiO2 on airways during pregnancy (2015) (13)
- Role of nitric oxide in human esophageal circular smooth muscle in vitro. (1995) (13)
- Benign pulmonary lesions that may be misdiagnosed as malignant. (1990) (13)
- Nuclear magnetic resonance spectroscopy of acute and evolving pulmonary hemorrhage. An in vitro study. (1987) (13)
- Role of the Adiponectin Binding Protein, T-Cadherin (cdh13), in Pulmonary Responses to Subacute Ozone (2013) (12)
- Selective lung leukosequestration after complement activation. (1988) (12)
- The role of complement receptors CD21/CD35 in positive selection of B-1 cells. (2000) (12)
- Activation of CB1R Promotes Lipopolysaccharide-Induced IL-10 Secretion by Monocytic Myeloid-Derived Suppressive Cells and Reduces Acute Inflammation and Organ Injury (2020) (12)
- Immunotoxicologic analysis of maternal transmission of asthma risk (2008) (11)
- Effects of combined ozone and air pollution particle exposure in mice. (2001) (11)
- The Influence of Programmed Cell Death in Myeloid Cells on Host Resilience to Infection with Legionella pneumophila or Streptococcus pyogenes (2016) (11)
- Attenuation of acid aspiration edema with phalloidin. (1990) (11)
- The relative resistance of children to sepsis mortality: from pathways to drug candidates (2018) (11)
- Fluorescence-based microplate bioassay for tumor necrosis factor. (1998) (10)
- Machine learning and deep analytics for biocomputing: Call for better explainability (2018) (10)
- Lung Macrophage Differentiation Antigens in Developing Fetal and Newborn Rat Lungs: A Quantitative Flow Cytometric Analysis with Immunohistochemistry (1999) (10)
- Expression of membrane glycoconjugates on sheep lung endothelium. (1995) (10)
- Intravascular chemoattractants inhibit diapedesis by selective receptor occupancy. (1991) (9)
- Genetic Variation in the Scavenger Receptor MARCO and Its Association with Chronic Obstructive Pulmonary Disease and Lung Infection in 10,604 Individuals (2012) (9)
- Mast cells mediate complement activation after acid aspiration. (2001) (9)
- Allergic Pulmonary Inflammation Promotes Airway Hyperresponsiveness and B/Rel Transcription Factors: c-Rel k NF-De (1999) (9)
- Childhood tolerance of severe influenza: a mortality analysis in mice. (2017) (8)
- Targeting TAZ-Driven Human Breast Cancer by Inhibiting a SKP2-p27 Signaling Axis (2018) (8)
- Channeling macrophage polarization by rocaglates increases macrophage resistance to Mycobacterium tuberculosis (2021) (8)
- Delayed Administration of Recombinant Plasma Gelsolin Improves Survival in a Murine Model of Penicillin-Sensitive and Resistant Pneumococcal Pneumonia. (2019) (7)
- Delayed administration of recombinant plasma gelsolin improves survival in a murine model of severe influenza. (2019) (7)
- Characterising Pre-pubertal Resistance to Death from Endotoxemia (2017) (6)
- Protection of macrophages from intracellular pathogens by miR‐182‐5p mimic—a gene expression meta‐analysis approach (2018) (6)
- Reciprocal Rb Inactivation and pl 6 INK 4 Expression in Primary Lung Cancers and Cell Lines 1 (2006) (6)
- Maladaptive oxidative stress cascade drives type I interferon hyperactivity in TNF activated macrophages promoting necrosis in murine tuberculosis granulomas (2020) (5)
- Risk For Asthma In Offspring Of Asthmatic Mothers: A Meta-analysis (2010) (5)
- Maternal Smoking Causes Abnormal Expression of the Vitamin D Receptor. (2009) (5)
- Ultrastructural analysis of a specific hamster alveolar macrophage antigen. (1985) (5)
- High hsCRP is associated with reduced lung function in structural firefighters. (2014) (4)
- MARCOing Monocytes for Elimination (2014) (4)
- Measurement of environmental particulate uptake by lung cells using flow cytometry. (1998) (4)
- A practical treatment for COVID‐19 and the next pandemic (2022) (4)
- Searching for a Lifeline: Transcriptome Profiling Studies of Influenza Susceptibility and Resistance (2017) (4)
- Why are children more resistant to mortality from severe infections? (2018) (4)
- Localization and quantification of a surface antigen on pulmonary macrophages of dystrophic hamsters by immunoelectron microscopy and flow cytometry (1986) (3)
- Membrane glycoconjugates expressed on sheep airway epithelium. (1994) (3)
- The Penh Police Are Not Infallible (2011) (3)
- Delayed Administration of Recombinant Plasma Gelsolin Improves Survival in a Murine Model of Penicillin-Susceptible and Penicillin-Resistant Pneumococcal Pneumonia (2019) (2)
- Increased susceptibility to intracellular bacteria and necrotic inflammation driven by a dysregulated macrophage response to TNF (2018) (2)
- N-Oleoyl dopamine induces IL-10 via central nervous system TRPV1 and improves endotoxemia and sepsis outcomes (2022) (2)
- The respiratory burst in rat alveolar macrophages is attenuated after displacement of phospholipid arachidonic acid by n-3 fatty acids in vivo (1995) (2)
- Delayed Therapy with Plasma Gelsolin Improves Survival in Murine Pneumococcal Pneumonia (2017) (2)
- All That Wheezes…. (2017) (2)
- Skeletal muscle reperfusion injury is mediated by neutrophils and the complement membrane attack complex. (1999) (2)
- Neutral endopeptidase activity in newborn and adult rabbit tracheas. (1997) (1)
- Pulmonary Pathology of ARDS: Diffuse Alveolar Damage (2016) (1)
- Pathology and Molecular Pathology of Lung Cancer (2017) (1)
- All That Wheezes... (2017) (1)
- Macrophage resilience and control of intracellular bacteria requires sst1-dependent integration of c-Myc, stress response and type I IFN pathways (2017) (1)
- AI Ethics and Values in Biomedicine - Technical Challenges and Solutions (2019) (1)
- The integrated stress response mediates type I interferon driven necrosis in Mycobacterium tuberculosis granulomas (2018) (1)
- Gender Differences in Asthma (2010) (1)
- Interleukin-2 leads to lung lymphosequestration, thromboxane generation, and rapid increase in permeability (1987) (1)
- functional unit on monocytic cells Mac-1 (CD11b/CD18) and the urokinase receptor (CD87) form a (2011) (1)
- A Role for Transforming Growth Factor-b 1 in the Increased Pneumonitis in Murine Allogeneic Bone Marrow Transplant Recipients With Graft-Versus-Host Disease After Pulmonary Herpes Simplex Virus Type 1 Infection (1998) (1)
- MARCO expression on pediatric alveolar macrophages (2004) (1)
- SON DNA‐binding protein mediates macrophage autophagy and responses to intracellular infection (2020) (1)
- Inhibition of TNF Synthesis by Antisense Oligonucleotides (1999) (1)
- Modeling childhood resistance to influenza mortality in mice (169.14) (2012) (1)
- Discovery Of Candidate Susceptibility Genes In A Murine Model Of Respiratory Syncytial Virus-Induced Bronchiolitis (2012) (0)
- Role of Neutrophil Adherence Receptors (2005) (0)
- Maternal asthma causes gene expression and epigenetic changes in neonatal dendritic cells (2008) (0)
- 69 Immunophenotyping of TCR and BCR clonotypes (2021) (0)
- Acid aspiration injury is mediated by the membrane attack complex and neutrophils (1999) (0)
- Particle-epithelial interaction : effect of priming and bystander neutrophils on IL-8 release (2003) (0)
- EST‐based gene silencing for identification of macrophage resistance mechanisms against Francisella tularensis (2009) (0)
- Epigenetic Analysis Of Human Fetal Airway Epithelium: Prenatal Programming By Maternal Smoking? (2012) (0)
- SON DNA-Binding Protein mediates 11 macrophage autophagy and responses 12 to intracellular infection (2020) (0)
- 3 Adaptive immune receptor repertoire profiling for biomarker discovery (2022) (0)
- Free Actin and Effects on Lung Macrophage Bacterial Defenses (2019) (0)
- Critical Role for Uremic Neutrophils Acute Uremia but Not Renal Inflammation Attenuates Aseptic Acute Lung Injury: A (2008) (0)
- Development of a Novel Model of Non-Bacteremic, Focal Pneumococcal Pneumonia in Young Rats (1999) (0)
- Splicing Factor SON Mediates Macrophage Susceptibility to Intracellular Pathogens (2015) (0)
- Effect of Statins in influenza (169.22) (2012) (0)
- Generation of a monoclonal antibody that blocks epithelial binding of unopsonized particles. (2003) (0)
- Channeling macrophage polarization via selective translation inhibition by rocaglates increases macrophage resistance to Mycobacterium tuberculosis (2019) (0)
- Scavenger receptor marco dampens acute inflammation and reduces survival in a mouse model of influenza infection: A harmful effect of macrophage tidiness? (2009) (0)
- Correction: The Influence of Programmed Cell Death in Myeloid Cells on Host Resilience to Infection with Legionella pneumophila or Streptococcus pyogenes (2017) (0)
- Statins improve innate resistance to pneumococcal pneumonia via lung macrophage NOS3 (2010) (0)
- TLR2 activation of TRIF controls both early inflammatory and late tolerance responses to Borrelia burgdorferi (180.11) (2012) (0)
- ToleranceCollagenous Structure in Innate Immune Role of Macrophage Receptor with (2013) (0)
- Natural antibody repertoire is dependent on complement receptors CD21/CD35 (1998) (0)
- Innate Common sst1-Mediated Mechanism of Vaccination Are Genetically Controlled via a Efficiency of Bacillus Calmette-Guérin Progression of Pulmonary Tuberculosis and (2013) (0)
- Characterizing the Protective Role of Pre‐Pubertal Status in Sepsis Outcomes (2015) (0)
- Innate Immunity-Mediated Mechanism of sst1 Common Vaccination Are Genetically Controlled via a Efficiency of Bacillus Calmette-Guérin Progression of Pulmonary Tuberculosis and (2007) (0)
- Retinoic Acid in Pulmonary Fibroblasts Primary Non-Small Cell Lung Cancers and Regulated by Stromelysin-3 Is Overexpressed by Stromal Elements in Updated (2006) (0)
- Macrophage Uptake of Unopsonized Staphylococcus aureus Strains: High‐Throughput Analysis by Scanning Cytometry (2009) (0)
- 168. THE DETECTION OF INFLAMMATION IN COLLAPSED LUNG BY NMR (1984) (0)
- Mice Offspring of Asthmatic and Normal Mother Differentially Modulates Asthma Risk in Family-Related Gene-Expressing T Cells Glucocorticoid-Induced TNF Receptor Targeting of CD 25 and (2007) (0)
- Gene expression profiling of enhanced lung inflammation during pregnancy (134.54) (2009) (0)
- Scavenger receptors and β-glucan receptors participate in the recognition of yeasts by murine macrophages (2011) (0)
- Effect of Statins in influenza (2012) (0)
- Infection Graft-Versus-Host Disease After Pulmonary Herpes Simplex Virus Type 1 Murine Allogeneic Bone Marrow Transplant Recipients With 1 in the Increased Pneumonitis in β A Role for Transforming Growth Factor- (2013) (0)
- Borrelia burgdorferi 2-Dependent Inflammatory Responses to TRIF Mediates Toll-Like Receptor (2014) (0)
- Immortalization and Characterization of Murine Alveolar Macrophages with SRA‐I/II and MARCO‐knockout by a J2 Retrovirus (2007) (0)
- Release of preformed IL‐12 by the macrophage scavenger receptor MARCO (2007) (0)
- Scavenger Receptors and Resistance to Inhaled Allergens (2007) (0)
- Sulforaphane improves MARCO expression, bacterial clearance and survival in post‐influenza bacterial pneumonia (145.1) (2014) (0)
- A Non-cuff Surgical Technique and Potent Peri-Transplant Immunomodulation Together Promote Long-term Survival of Murine Orthotopic Lung Allografts (2018) (0)
- Functional genome‐wide analysis of macrophage clearance of Francisella tularensis: novel roles for CD137 and CD137 ligand (2011) (0)
- MARCO modulates asbestos‐induced Rac1 mitochondrial import and H2O2 production (2012) (0)
- ToleranceStructure in Innate Immune Role of Macrophage Receptor with (2014) (0)
- Bleomycin-Mediated Lung Injury Metalloproteinase-8 during Profibrotic Activities for Matrix (2013) (0)
- P007. Increased female resistance to pneumonia via lung macrophage NOS3 (2006) (0)
- Role of macrophage scavenger receptor MARCO in innate immunity against Influenza (133.29) (2009) (0)
- In situ quantification of macrophage AIM2 inflammasome activation during Francisella tularensis infection by fluorescence proximity ligation (2012) (0)
- An Essential Role Of MARCO In Gram-negative Bacterial Pneumonia (2010) (0)
- decreases airway resistance and responsiveness Expression of nitric oxide synthase-2 in the lungs (2015) (0)
- N-Oleoyl dopamine induces IL-10 via central nervous system TRPV1 and improves endotoxemia and sepsis outcomes (2022) (0)
- Bioinformatic meta-analysis identifies a new role for macrophage E2F transcription factors during interaction with intracellular pathogens. (P3102) (2013) (0)
- Systemic Inflammation Predicts Reduced Lung Function In Structural Firefighters (2012) (0)
- Characterizing childhood resistance to deadly immune dysfunction in severe infections (2017) (0)
- Inhibition ofSphincter ofOddiFunction bytheNitric OxideCarrier S-nitroso- N-acetylcysteine inRabbits andHumans (1994) (0)
- Abstract LB172: Improved T-cell and B-cell receptor repertoire profiling and immunophenotyping for biomarker discovery (2023) (0)
- Gene expression profiling of enhanced lung inflammation during pregnancy (2009) (0)
- Lung Defenses (2008) (0)
- Delayed administration of recombinant plasma gelsolin improves survival in a murine model of severe influenza (2019) (0)
- This information is current as Health and Disease Scavenger Receptors and Their Roles in A Consensus Definitive Classification of (2017) (0)
- Limit Pulmonary Dendritic Cell Migration Scavenger Receptors SR-AI/II and MARCO (2007) (0)
- Glucose metabolism and DNA methylation of offspring are altered by maternal sodium restriction (2013) (0)
- Maternal Transmission of Asthma Risk: Epigenetic Changes in CD4 T Cells of Asthma-Susceptible Offspring. (2009) (0)
- Award Number: W81XWH-06-1-0289 TITLE: Scavenger Receptors and Resistance to Inhaled Allergens (2007) (0)
- NO turning back. (2014) (0)
- Airway Inflammation in Mice Adam8 Limits the Development of Allergic (2013) (0)
- 2002 North American Referee List (2002) (0)
- Genome-Wide Analysis Shows Linkage of Gene Expression and Altered DNA Methylation in Pro-Allergic Neonatal Dendritic Cells. (2009) (0)
- Role of macrophage scavenger receptor MARCO in lung innate defenses against influenza (2008) (0)
- Leukocytes Mediate Acid Aspiration Induced Multi-Organ Injury. (1991) (0)
- Maternal Stress and Transmission of Asthma Risk. (2009) (0)
- Human Decidual Macrophages Expressed by Clostridium sordellii for Structure, Is the Major Phagocytic Receptor Macrophage Receptor with Collagenous The Class A Scavenger Receptor, (2010) (0)
- Human Alveolar Macrophages Unopsonized Particles and Bacteria on MARCO Is the Major Binding Receptor for (0)
- Lavage of Leukotriene B4 Induces Lung Generation of Tumor Necrosis Factor-A and Neutrophil Diapedesis. (1991) (0)
- Abstract 5868: Cell barcoding, genetic screens and expression profiling at a single-cell level (2020) (0)
- Free Actin Impairs Macrophage Bacterial Defense: Reversal by Plasma Gelsolin (2015) (0)
- 1992 referees (2004) (0)
- Macrophage scavenger receptor MARCO modulates early events in innate immunity against Influenza (2010) (0)
- Maternal exposure to diesel exhaust particles alters neonatal dendritic cell DNA methylation profiles and skews function towards pro-Th2 responses. (141.13) (2010) (0)
- Plasma gelsolin enhances lung macrophage host defense against bacterial pneumonia in mice (2012) (0)
- Abstract 625: Immunophenotyping of TCR and BCR clonotypes (2022) (0)
- Carbon Monoxide Enhances The Bactericidal Activity Of Macrophages Infected With Enterococci Faecalis (2010) (0)
- Pregnancy smoking: Tissue- and sex-specific drift of Igf1r and Igf1 methylation in mouse fetuses and neonates (2017) (0)
- Macrophage Killing of Intracelluar Pathogen Fransicella tularensis: Functional Genomic Analysis (2009) (0)
- Transmission of Asthma Susceptibility Allergen-Independent Maternal (2003) (0)
- Androstenetriol enhances lung macrophage host defense against bacterial pneumonia in mice (2016) (0)
- Channeling macrophage polarization by using a selective translation inhibitor (2019) (0)
- Characterising Pre-pubertal Resistance to Death from Endotoxemia (2017) (0)
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