Leszek Borysiewicz

Leszek Borysiewicz's AcademicInfluence.com Rankings

Leszek Borysiewicz

Biology

#988

World Rank

#1711

Historical Rank

Immunology

#80

World Rank

#86

Historical Rank

biology Degrees

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Biology

Why Is Leszek Borysiewicz Influential?

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According to Wikipedia, Sir Leszek Krzysztof Borysiewicz is a British professor, immunologist and scientific administrator. He served as the 345th Vice-Chancellor of the University of Cambridge, his term of office started on 1 October 2010 and ended on 1 October 2017. Borysiewicz also served as chief executive of the Medical Research Council of the UK from 2007-2010 and has held the role of chairman at Cancer Research UK since 2016.

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Leszek Borysiewicz's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Monocytes are a major site of persistence of human cytomegalovirus in peripheral blood mononuclear cells. (1991) (735)
Grand challenges in chronic non-communicable diseases (2007) (677)
Surface expression of HLA-E, an inhibitor of natural killer cells, enhanced by human cytomegalovirus gpUL40. (2000) (651)
A recombinant vaccinia virus encoding human papillomavirus types 16 and 18, E6 and E7 proteins as immunotherapy for cervical cancer (1996) (549)
Quantitative analysis of the human immunodeficiency virus type 1 (HIV- 1)-specific cytotoxic T lymphocyte (CTL) response at different stages of HIV-1 infection: differential CTL responses to HIV-1 and Epstein- Barr virus in late disease (1993) (454)
Human HLA-A0201-restricted cytotoxic T lymphocyte recognition of influenza A is dominated by T cells bearing the V beta 17 gene segment (1995) (309)
Human cytomegalovirus inhibits maturation and impairs function of monocyte-derived dendritic cells. (2002) (264)
Human cytomegalovirus-specific cytotoxic T cells. Relative frequency of stage-specific CTL recognizing the 72-kD immediate early protein and glycoprotein B expressed by recombinant vaccinia viruses (1988) (259)
Innate Recognition of Bacteria in Human Milk Is Mediated by a Milk-Derived Highly Expressed Pattern Recognition Receptor, Soluble Cd14 (2000) (254)
Infiltration of cervical cancer tissue with human papillomavirus-specific cytotoxic T-lymphocytes. (1997) (225)
Hereditary C1q deficiency and systemic lupus erythematosus. (1994) (215)
CD8highCD57+ T lymphocytes in normal, healthy individuals are oligoclonal and respond to human cytomegalovirus. (1995) (181)
UL40-mediated NK evasion during productive infection with human cytomegalovirus (2002) (167)
The Human Cytomegalovirus MHC Class I Homolog UL18 Inhibits LIR-1+ but Activates LIR-1− NK Cells1 (2007) (157)
Expression of an intercellular adhesion molecule, ICAM-1, by human thyroid cells. (1989) (144)
Construction and characterisation of a recombinant vaccinia virus expressing human papillomavirus proteins for immunotherapy of cervical cancer (1996) (133)
Human cytomegalovirus‐specific cytotoxic T cells: their precursor frequency and stage specificity (1988) (132)
Soluble CD14 acts as a negative regulator of human T cell activation and function (1999) (132)
Subsets of CD8 +, CD57+ cells in normal, healthy individuals: correlations with human cytomegalovirus (HCMV) carrier status, phenotypic and functional analyses (1993) (128)
Use of fluorogenic histocompatibility leukocyte antigen-A*0201/HPV 16 E7 peptide complexes to isolate rare human cytotoxic T-lymphocyte-recognizing endogenous human papillomavirus antigens. (2000) (122)
Clinical studies of human papilloma vaccines in pre-invasive and invasive cancer. (2001) (119)
Antigen Processing Defects in Cervical Carcinomas Limit the Presentation of a CTL Epitope from Human Papillomavirus 16 E61 (2001) (119)
Human papillomavirus-specific cytotoxic T lymphocytes in patients with cervical intraepithelial neoplasia grade III. (1997) (119)
Human cytomegalovirus‐specific cytotoxic T lymphocytes: requirements for in vitro generation and specificity (1983) (116)
High frequency of memory and effector gag specific cytotoxic T lymphocytes in HIV seropositive individuals. (1990) (109)
Induction of immunoglobulin G Fc receptors by recombinant vaccinia viruses expressing glycoproteins E and I of herpes simplex virus type 1 (1990) (106)
TCR signaling thresholds regulating T cell development and activation are dependent upon SHP-1. (1999) (105)
Human Cytomegalovirus pp65- and Immediate Early 1 Antigen-Specific HLA Class I-Restricted Cytotoxic T Cell Responses Induced by Cross-Presentation of Viral Antigens1 (2001) (103)
Cytomegalovirus infection in heart-lung transplant recipients: risk factors, clinical associations, and response to treatment. (1991) (97)
T cell responses to vaccines in infants: defective IFNγ production after oral polio vaccination (2002) (93)
Human cytomegalovirus-infected cells have unstable assembly of major histocompatibility complex class I complexes and are resistant to lysis by cytotoxic T lymphocytes (1994) (91)
Peak expiratory flow rates before and after exercise in schoolchildren (1974) (87)
Cutting Edge: Human B Cell Function Is Regulated by Interaction with Soluble CD14: Opposite Effects on IgG1 and IgE Production1 (2000) (81)
Lysis of human cytomegalovirus infected fibroblasts by natural killer cells: demonstration of an interferon-independent component requiring expression of early viral proteins and characterization of effector cells. (1985) (73)
Epstein Barr virus-specific immune defects in patients with persistent symptoms following infectious mononucleosis. (1986) (69)
Analysis of the human T-cell response to picornaviruses: identification of T-cell epitopes close to B-cell epitopes in poliovirus (1993) (69)
Detection and biochemical characteristics of the receptor for complexes of soluble CD14 and bacterial lipopolysaccharide. (1997) (69)
Fine specificity of cellular immune responses in humans to human cytomegalovirus immediate-early 1 protein (1991) (69)
Cytotoxic T cell immunity to human cytomegalovirus glycoprotein B (1996) (63)
HLA Class II Polymorphisms and Susceptibility to Recurrent Respiratory Papillomatosis (2003) (60)
Human cytomegalovirus infection. (1989) (54)
CD8high+ (CD57+) T cells in patients with rheumatoid arthritis. (1997) (53)
Varicella-zoster virus-specific cytotoxic T lymphocytes (Tc): detection and frequency analysis of HLA class I-restricted Tc in human peripheral blood (1987) (53)
Influenza A antigen exposure selects dominant Vbeta17+ TCR in human CD8+ cytotoxic T cell responses. (2001) (51)
Cytomegalovirus - its cellular immunology and biology. (1986) (48)
CD8high(CD57+) T cells in normal, healthy individuals specifically suppress the generation of cytotoxic T lymphocytes to Epstein‐Barr virus‐transformed B cell lines (1994) (47)
Cervical human papillomavirus infection and squamous intraepithelial lesions in rural Gambia, West Africa: viral sequence analysis and epidemiology (2005) (46)
Functional differences between influenza A-specific cytotoxic T lymphocyte clones expressing dominant and subdominant TCR. (2001) (43)
The role of CD8+, CD57+ cells in human cytomegalovirus and other viral infections. (1995) (42)
Development of a model for cytomegalovirus infection of oligodendrocytes. (1997) (38)
Immunoaffinity purification of a 72K early antigen of human cytomegalovirus: analysis of humoral and cell-mediated immunity to the purified polypeptide. (1987) (30)
Peripheral blood T cell activation after radioiodine treatment for Graves' disease. (1990) (29)
Serum folate and chronic fatigue syndrome (1993) (29)
Cytotoxic T cells and human herpes virus infections. (1994) (28)
Human cytomegalovirus infection downregulates expression of the cellular aminopeptidases CD10 and CD13. (1998) (27)
Down-regulation of integrin alpha 1/beta 1 expression and association with cell rounding in human cytomegalovirus-infected fibroblasts. (1994) (27)
Infection and reactivation with cytomegalovirus strains in lung transplant recipients. (1991) (25)
Renal failure in familial lecithin: cholesterol acyltransferase deficiency. (1982) (25)
Acute fatigue in chronic fatigue syndrome patients (1999) (23)
HLA‐DR expression in a human colonic carcinoma cell linexs (1985) (23)
Human cytotoxic T cell responses to vaccinia virus vaccination. (1991) (23)
A malignant astrocytoma in a patient with AIDS: a possible association between astrocytomas and HIV infection. (1996) (22)
Festival Lessons (2014) (22)
The immunosuppressive effects of measles virus on T cell function--failure to affect IL-2 release or cytotoxic T cell activity in vitro. (1985) (21)
The use of human leucocyte antigen class I transgenic mice to investigate human immune function. (1998) (17)
Gene therapy and viral vaccination: the interface. (1995) (17)
Chronic fatigue syndrome and susceptibility to upper respiratory tract illness (1999) (16)
Clinical studies of human papilloma vaccines in cervical cancer. (2001) (16)
Consequences of live poliovirus vaccine administration in chronic fatigue syndrome (1997) (15)
Suppressive role of NK cells in pokeweed mitogen-induced immunoglobulin synthesis: effect of depletion/enrichment of Leu 11b+ cells. (1988) (14)
A study of the structure of the gene for lecithin: cholesterol acyltransferase in four unrelated individuals with familial lecithin: cholesterol acyltransferase deficiency. (1988) (13)
Regulation of major histocompatibility complex class II antigen expression by the FRTL-5 rat thyroid cell line. (1987) (13)
Circulating T-cell populations during mercuric chloride-induced nephritis in the Brown Norway rat. (1987) (12)
Pathogenesis of human cytomegalovirus disease and the kidney. (1991) (12)
Generation of in vitro autologous human cytotoxic T-cell response to E7 and HER-2/neu oncogene products using ex-vivo peptide loaded dendritic cells. (1997) (11)
Automation of limiting dilution cytotoxicity assays. (1990) (11)
Prevention is better than cure. (2009) (11)
Androgen production in a patient with Klinefelter's syndrome and choriocarcinoma. (1980) (9)
Heterogeneity amongst natural killer cells revealed by limiting dilution culture; selectivity against virus-infected and tumour cell targets. (1993) (8)
Immune Response to Virus-Infected Cells (1986) (7)
Scombrotoxic atrial flutter. (1981) (7)
Cell sorting using immunomagnetic beads. (1992) (6)
Corneal opacification and familial disorders affecting plasma high-density lipoprotein. (1982) (6)
Requirement for CD28 co-stimulation is lower in SHP-1 deficient T cells (2001) (6)
Acute fatigue in chronic fatigue syndrome (1999) (6)
Grand Rounds—University Hospital of Wales: Focal myositis mimicking acute psoas abscess (1997) (4)
Training in infectious diseases and tropical medicine in Britain. (2000) (3)
Immunology of Infection (1994) (3)
Detection and biochemical characteristics of the receptor for complexes of bacterial lipopolysaccharide (LPS) and soluble CD14 (sCD14) (1997) (3)
Grand Rounds—University Hospital of Wales, Cardiff: Pyrexia of unknown origin (1997) (2)
This information is current as Epitope from Human Papillomavirus 16 E 6 Carcinomas Limit the Presentation of a CTL Antigen Processing Defects in Cervical Cerundolo and (2001) (2)
Uniting research into human and animal health (2010) (2)
Therapeutic vaccines for cervical cancer: concept and clinical results. (1997) (2)
Cell sorting using immunomagnetic beads. (1992) (1)
Vaccine strategies for cancer (2000) (1)
Prevention is better than cure (2010) (1)
Viruses and autoimmunity. (1990) (1)
Banking on the future of stem cells. Leszek Borysiewicz, head of the UK Medical Research Council (MRC), interviewed by Monya Baker. (2008) (1)
Plagues and Medicine (2017) (1)
Viral immunopathology. (1985) (1)
INDUCTION OF IMMUNOGLOBULIN-G FC-RECEPTORS BY RECOMBINANT VACCINIA VIRUSES EXPRESSING GLYCOPROTEIN-E AND GLYCOPROTEIN-I OF HERPES-SIMPLEX VIRUS TYPE-1 (1990) (0)
Cell mediated immunity to human cytomegalovirus infection (cytotoxic T cell and natural killer cell mediated lysis of human cytomegalovirus infected cells) (1986) (0)
Inﬂuenza A antigen exposure selects dominant V β 17 (cid:1) TCR in human CD8 (cid:1) cytotoxic T cell responses (2001) (0)
Quantitating the HIV-1-Specific Cytotoxic T Cell Response (1992) (0)
Theimmunosuppressive effects ofmeasles virus on Tcell function-failure toaffect IL-2release or cytotoxic Tcell activity invitro (1985) (0)
Opposite Effects on IgG 1 and IgE Production Regulated by Interaction with Soluble CD 14 : Cutting Edge : Human B Cell Function (2000) (0)
Therapeutic Vaccines for Cervical Cancer (1997) (0)
Heterogeneity amongst Natural Killer Cells Revealed by Clones with Selectivity against Virus Infected and Tumour Targets (1989) (0)
Peptide loaded human autologous dendritic cells (DC's) as a potential anti-cancer vaccine (1997) (0)
The Immunology and Pathogenesis of Persistent Virus Infections (1994) (0)
Analysis of immunocytochemically detectable HPV 16 E7 overexpression in cervical cancer (1997) (0)
Activates LIR-1 but + Homolog UL 18 Inhibits LIR-1 The Human Cytomegalovirus MHC Class (2007) (0)
Importance of TCRBV17 usage in the HLA-A0201-restricted influenza a specific cytotoxic T lymphocyte response: A comparison of maternal & cord blood (1997) (0)
Target specificity of immunoregulation by natural killer cells. (1989) (0)
Development and initial clinical studies of TA-HPV in cervical cancer (1995) (0)
monocyte-derived dendritic cells Human cytomegalovirus inhibits maturation and impairs function of (2013) (0)
581 Immunotherapy in cervical cancer patients (1995) (0)
HPV-specific cytotoxic T lymphocyte responses in patients with CIN III (1997) (0)
Newsmaker interview: Leszek Borysiewicz. Cambridge seeks global reach, says university head. Interview by Colin Macilwain. (2011) (0)
Lymphocyte culture from routine endomyocardial biopsies: lack of clinical or pathological correlations. (1993) (0)
Vaccinia-based human papillomavirus vaccines in cervical cancer (2000) (0)
LYMPHOCYTE CULTURE FROM ENDOMYOCARDIAL BIOPSIES: EFFECTS OF POLYCLONAL T CELL ACTIVATORS COMPARED WITH INTERLEUKIN‐2 ALONE (1994) (0)
UK research reform: get the facts straight (2016) (0)
Medical Research Council values basic research (2008) (0)

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Leszek Borysiewicz's Academic­Influence.com Rankings