Liisa Ahtee
#110,993
Most Influential Person Now
Finnish professor of pharmacology
Liisa Ahtee's AcademicInfluence.com Rankings
Liisa Ahteemedical Degrees
Medical
#1948
World Rank
#2336
Historical Rank
Pharmacology
#241
World Rank
#283
Historical Rank

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Liisa Ahtee's Degrees
- PhD Pharmacology University of Helsinki
- Masters Pharmacy University of Helsinki
Why Is Liisa Ahtee Influential?
(Suggest an Edit or Addition)According to Wikipedia, Liisa Marjatta Ahtee was born on 2 October 1937 in Turku to Aaro Veli Vilho and Lyyli Iida Kyllikki Ahtee. She is an internationally esteemed Finnish pharmacologist and professor emeritus, who served as pharmacology and biological medicine standardization chair at the University of Helsinki from 1975 to 2002.
Liisa Ahtee's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Opiate‐receptor mediated changes in monoamine synthesis in rat brain (1978) (95)
- Differential nicotinic regulation of the nigrostriatal and mesolimbic dopaminergic pathways: Implications for drug development (2007) (88)
- The Effects of Acute Nicotine on the Metabolism of Dopamine and the Expression of Fos Protein in Striatal and Limbic Brain Areas of Rats during Chronic Nicotine Infusion and Its Withdrawal (1999) (81)
- The effect of narcotic analgesics on the homovanillic acid content of rat nucleus caudatus. (1973) (80)
- Constitutive Ret Activity in Knock-In Multiple Endocrine Neoplasia Type B Mice Induces Profound Elevation of Brain Dopamine Concentration via Enhanced Synthesis and Increases the Number of TH-Positive Cells in the Substantia Nigra (2007) (78)
- 5-Hydroxytryptamine and 5-hydroxyindolylacetic acid content in brain of rat strains selected for their alcohol intake. (1972) (72)
- Regulation of nicotinic receptors in the brain of mice withdrawn from chronic oral nicotine treatment (1998) (70)
- Expression of fos protein in various rat brain areas following acute nicotine and diazepam (1996) (68)
- Effects of chronic oral nicotine treatment and its withdrawal on locomotor activity and brain monoamines in mice (2000) (65)
- In heterozygous GDNF knockout mice the response of striatal dopaminergic system to acute morphine is altered (2006) (64)
- Dopamine and noradrenaline content in the brain of rat strains selected for their alcohol intake. (1975) (61)
- Changes in brain monoamine metabolism during withdrawal from chronic oral self-administration of morphine and in response to a morphine challenge in the withdrawn state. (1989) (60)
- The analgesic and sedative effects of nicotine in white mice, rabbits and golden hamsters. (1968) (60)
- Effects of ethanol on the accumbal output of dopamine, GABA and glutamate in alcohol-tolerant and alcohol-nontolerant rats (2002) (60)
- Increased extracellular dopamine concentrations and FosB/ΔFosB expression in striatal brain areas of heterozygous GDNF knockout mice (2004) (59)
- Catalepsy and stereotypies in rats treated with methadone; relation to striatal dopamine. (1974) (59)
- Effect of ethanol dependence and withdrawal on the catecholamines in rat brain and heart. (2009) (59)
- Chronic Nicotine Administration in the Drinking Water Affects the Striatal Dopamine in Mice (2000) (57)
- Effects of chronic nicotine administration and its withdrawal on striatal FosB/ΔFosB and c-Fos expression in rats and mice (2006) (56)
- Plasma nicotine and cotinine concentrations in mice after chronic oral nicotine administration and challenge doses (1993) (53)
- Alterations in BDNF and phospho-CREB levels following chronic oral nicotine treatment and its withdrawal in dopaminergic brain areas of mice (2011) (51)
- REGIONAL DISTRIBUTION OF BRAIN 5‐HYDROXYTRYPTAMINE IN RAT STRAINS SELECTED FOR THEIR ALCOHOL INTAKE * (1973) (50)
- 5-HT3 receptor antagonist MDL 72222 dose-dependently attenuates cocaine- and amphetamine-induced elevations of extracellular dopamine in the nucleus accumbens and the dorsal striatum. (1996) (50)
- Involvement of Opioid μ1 Receptors in Morphine-Induced Conditioned Place Preference In Rats (1997) (48)
- Metoclopramide induces catalepsy and increases striatal homovanillic acid content in mice. (2009) (48)
- Chronic nicotine modifies the effects of morphine on extracellular striatal dopamine and ventral tegmental GABA (2008) (46)
- Evidence for involvement of central NA neurones in alcohol intake. Increased alcohol consumption after degeneration of the NA pathway to the cortex cerebri (1975) (46)
- Morphine-nicotine interaction in conditioned place preference in mice after chronic nicotine exposure. (2008) (44)
- Effect of Ketamine Anaesthesia on the Content of Monoamines and their Metabolites in the Rat Brain (1976) (43)
- Enhanced morphine- and cocaine-induced behavioral sensitization in alcohol-preferring AA rats (1999) (42)
- Involvement of Opioid μ1-Receptors in Opioid-Induced Acceleration of Striatal and Limbic Dopaminergic Transmission (1999) (42)
- EFFECT OF MECAMYLAMINE ON THE FATE OF DOPAMINE IN STRIATAL AND MESOLIMBIC AREAS OF RAT BRAIN; INTERACTION WITH MORPHINE AND HALOPERIDOL (1978) (38)
- Time and brain region specific up-regulation of low affinity neuronal nicotinic receptors during chronic nicotine administration in mice. (2005) (37)
- The effect of drugs upon the uptake of 5‐hydroxytryptamine and metaraminol by human platelets (1971) (36)
- Enhanced motor activity and brain dopamine turnover in mice during long-term nicotine administration in the drinking water (2001) (36)
- Cerebral monoamine neurotransmitters in opioid withdrawal and dependence. (1987) (36)
- The nicotine-induced changes in striatal dopamine metabolism of mice depend on body temperature (1986) (35)
- Comparison of the effects of nicotine and epibatidine on the striatal extracellular dopamine. (2004) (34)
- INHIBITION BY APOMORPHINE OF THE METOCLOPRAMIDE‐INDUCED CATALEPSY AND INCREASE IN STRIATAL HOMOVANILLIC ACID CONTENT (1975) (33)
- Effects of repeated morphine on locomotion, place preference and dopamine in heterozygous glial cell line‐derived neurotrophic factor knockout mice (2007) (32)
- Chronic oral nicotine administration affects the circadian rhythm of dopamine and 5-hydroxytryptamine metabolism in the striata of mice (1995) (31)
- Effect of quinpirole on striatal dopamine release and locomotor activity in nicotine-treated mice. (2006) (30)
- The effect of benzodiazepines and atropine on exploratory behaviour and motor activity of mice (1970) (29)
- Tolerance to nicotine's effects on striatal dopamine metabolism in nicotine-withdrawn mice. (1996) (29)
- Induction of Fos-immunostaining by nicotine and nicotinic receptor antagonists in rat brain (2001) (28)
- Effect of morphine on locomotor activity and striatal monoamine metabolism in nicotine-withdrawn mice (2006) (28)
- The effects of systemically administered taurine and N-pivaloyltaurine on striatal extracellular dopamine and taurine in freely moving rats (2003) (27)
- Chronic ethanol administration decreases 5-HT and increases 5-HIAA concentration in rat brain. (2009) (27)
- The effects of nicotine on locomotor activity and dopamine overflow in the alcohol-preferring AA and alcohol-avoiding ANA rats. (2000) (26)
- Mecamylamine decreases accumbal dopamine output in mice treated chronically with nicotine (2002) (26)
- Effect of Acute Nicotine on Fos Protein Expression in Rat Brain During Chronic Nicotine and Its Withdrawal (2000) (25)
- Retardation of cerebral dopamine turnover after morphine withdrawal and its enhanced acceleration by acute morphine administration in rats (1984) (25)
- Characterization of the striatal dopaminergic neurotransmission in MEN2B mice with elevated cerebral tissue dopamine (2008) (25)
- Morphine- and cocaine-induced conditioned place preference: Effects of quinpirole and preclamol (1996) (25)
- Catalepsy and stereotyped behaviour in rats treated chronically with methadone: relation to brain homovanillic acid content (1973) (24)
- Effects of nicotine and epibatidine on locomotor activity and conditioned place preference in rats (2005) (24)
- Comparison of the effects of epibatidine and nicotine on the output of dopamine in the dorsal and ventral striatum of freely-moving rats (2000) (23)
- Augmentation of morphine-induced changes in brain monoamine metabolism after chronic naltrexone treatment. (1990) (23)
- The effect of narcotic analgesics on the uptake of 5‐hydroxytryptamine and (—)‐metaraminol by blood platelets (1973) (22)
- Intrastriatal taurine increases striatal extracellular dopamine in a tetrodotoxin-sensitive manner in rats (1996) (22)
- Morphine-stimulated metabolism of striatal and limbic dopamine is dissimilarly sensitized in rats upon withdrawal from chronic morphine treatment (1994) (22)
- Effects of morphine on metabolism of dopamine and serotonin in brains of alcohol-preferring AA and alcohol-avoiding ANA rats. (1999) (21)
- Role of Cerebral Dopamine and Noradrenaline in the Morphine-induced Locomotor Sensitisation in Mice (1997) (20)
- Effects on gene expression (1994) (20)
- Voluntary alcohol drinking selectively accelerates dopamine release in the ventral striatum as reflected by 3-methoxytyramine levels (1997) (19)
- Blood Platelet as a Model for Monoaminergic Neurons (1971) (19)
- Conditioned Place Preference Induced by a Combination of l-Dopa and a COMT Inhibitor, Entacapone, in Rats (1998) (19)
- Effect of cholingeric drugs on methadone-induced catalepsy and stereotypies in rats treated chronically with methadone. (1976) (19)
- The effect of nicotine in combination with various dopaminergic drugs on nigrostriatal dopamine in rats (2005) (18)
- Cerebral dopamine and noradrenaline turnover and effects of morphine test dose in rats withdrawn from 20 days' morphine treatment. (1983) (18)
- Rotational behaviour in AA and ANA rats after repeated administration of morphine and cocaine (2002) (17)
- Effect of forced chronic oral nicotine exposure on intravenous self-administration and rewarding properties of acute nicotine. (2008) (17)
- Involvement of opioid mu 1 receptors in morphine-induced conditioned place preference in rats. (1997) (17)
- Effects of repeated cocaine treatment on striatal dopamine release in alcohol-preferring AA and alcohol-avoiding ANA rats (2001) (16)
- Letters to the Editor: Distribution of some phenothiazines in red blood cells and platelets (1966) (15)
- Concurrent nimodipine attenuates the withdrawal signs and the increase of cerebral dihydropyridine binding after chronic morphine treatment in rats (1993) (15)
- Taurine and its derivatives alter brain dopamine metabolism similarly to GABA in mice and rats. (1985) (15)
- Effect of neonatal nomifensine exposure on adult behavior and brain monoamines in rats (2005) (15)
- Effects of selective opioid receptor antagonists on morphine-induced changes in striatal and limbic dopamine metabolism. (1995) (14)
- Methadone increases intracellular calcium in SH‐SY5Y and SH‐EP1‐hα7 cells by activating neuronal nicotinic acetylcholine receptors (2005) (14)
- Nicotine and epibatidine alter differently nomifensine-elevated dopamine output in the rat dorsal and ventral striatum. (2005) (14)
- Effect of nalorphine and antiparkinsonian drugs on methadone-induced rigidity; relation to homovanillic acid content of nucleus caudatus. (1972) (13)
- The effects of acute nicotine on the body temperature and striatal dopamine metabolism of mice during chronic nicotine infusion (2000) (13)
- Morphine-induced analgesia in rats withdrawn from concurrent nimodipine and morphine treatment (1999) (13)
- Effects of repeated morphine on cerebral dopamine release and metabolism in AA and ANA rats (2000) (13)
- Dextromethorphan inhibits 5‐hydroxytryptamine uptake by human blood platelets and decreases 5‐hydroxyindoleacetic acid content in rat brain (1975) (13)
- Behavioural and neurochemical sensitization of morphine-withdrawn rats to quinpirole (1996) (13)
- Antagonism of the nicotine-induced changes of the striatal dopamine metabolism in mice by mecamylamine and pempidine (1988) (13)
- The haemolytic effect of some phenothiazine derivatives. (1965) (12)
- Pineal melatonin and brain transmitter monoamines in CBA mice during chronic oral nicotine administration (2002) (12)
- The antiopioid peptide, neuropeptide FF, enhances the effects of acute morphine on the cerebral monoamines in rats. (1995) (12)
- Chronic morphine administration decreases 5-hydroxytryptamine and 2-hydroxyindoleacetic acid content in the brain of rats. (1980) (12)
- Differences in the effects of morphine on the alpha-methyl-p-tyrosine-induced depletion of dopamine and noradrenaline in various areas of the mouse brain. (1987) (12)
- Effect of drugs on metoclopramide-induced catalepsy and increase in striatal homovanillic acid content. (1975) (11)
- Accumbal FosB/ΔFosB immunoreactivity and conditioned place preference in alcohol-preferring AA rats and alcohol-avoiding ANA rats treated repeatedly with cocaine (2007) (11)
- Comparison of central nervous system actions of taurine and N-pivaloyltaurine. (1985) (11)
- Differences in basal and morphine-induced FosB/ΔFosB and pCREB immunoreactivities in dopaminergic brain regions of alcohol-preferring AA and alcohol-avoiding ANA rats (2009) (11)
- 5-Hydroxytryptamine release from blood platelets and haemolysis of red blood cells of rabbit induced by phenothiazines and related compounds. (1966) (11)
- Effect of muscarinic cholinergic drugs on morphine-induced catalepsy, antinociception and changes in brain dopamine metabolism (1977) (10)
- Effects of morphine on metabolism of dopamine and serotonin in the dorsal and ventral striatum of alcohol preferring AA and alcohol avoiding ANA rats (1999) (10)
- Effects of repeated morphine treatment on metabolism of cerebral dopamine and serotonin in alcohol-preferring AA and alcohol-avoiding ANA rats. (2001) (10)
- Opioid mechanisms in regulation of cerebral monoamines in vivo. (1980) (9)
- Taurine infused intrastriatally elevates, but intranigrally decreases striatal extracellular dopamine concentration in anaesthetised rats (2005) (9)
- Locally infused taurine, GABA and homotaurine alter differently the striatal extracellular concentrations of dopamine and its metabolites in rats (2005) (9)
- Effect of atropine, methylatropine, methylscopolamine and pilocarpine on salivary secretion and heart rate in man. (1966) (9)
- The binding of some phenothiazines to human serum in vitro. (1967) (9)
- Potentiation of 5-hydroxytryptamine release from platelets by desmethylation of chlorpromazine and related agents. (2009) (8)
- The role of dopamine in pilocarpine-induced catalepsy (2004) (7)
- Comparison of the effects of nicotine and epibatidine given in combination with nomifensine on rotational behaviour in rats (2005) (7)
- Comparison of the effects of intraventricular taurine, GABA and homotaurine on serum prolactin levels in male rats. (1989) (7)
- MORPHINE RELEASES GLUTAMATE THROUGH AMPA RECEPTORS IN THE VENTRAL TEGMENTAL AREA: A MICRODIALYSIS STUDY IN CONSCIOUS RATS (2003) (7)
- Interactions of some analgesics and antidepressants with phenelzine or reserpine in the mouse. (1974) (7)
- The effect of pethidine on the 5‐hydroxytryptamine and 5‐hydroxyindoleacetic acid content of the mouse brain (1971) (7)
- Effects of taurine, homotaurine and GABA on hypothalamic and striatal dopamine metabolism (1992) (7)
- Acceleration of cerebral noradrenaline turnover after morphine withdrawal and its retardation by acute morphine administration in rats (1984) (7)
- Proceedings: Effects of sympathomimetic amines on rabbit platelet aggregation in vitro. (1972) (6)
- Surface activity of phenothiazines and related compounds. (1966) (6)
- Subcellular distribution of some phenothiazines in blood platelets of rabbit (1968) (6)
- Release of adrenaline and noradrenaline by some phenothiazines from the bovine adrenal gland. (1966) (6)
- Effect of some phenothiazine derivatives and related agents on the accumulation and distribution of 5-hydroxytryptamine in blood platelets. (1968) (6)
- Effects of morphine in rats withdrawn from repeated nifedipine administration. (1999) (6)
- Regional differences in cerebral noradrenaline turnover in mice withdrawn from repeated morphine treatment and tolerance to the effects of acute morphine. (1995) (5)
- Dual action of methadone on 5-HT synthesis and metabolism (1979) (5)
- The uptake and metabolism of noradrenaline in the isolated heart of spontaneously hypertensive rat. (1973) (5)
- Effect of narcotic analgesics on the striatal homovanillic acid content in mice; relation to antinociceptive effect. (1976) (5)
- Effects of intraventricular taurine, homotaurine and GABA on serum prolactin and thyrotropin levels in female and in male rats (2005) (5)
- Withdrawal from repeated morphine sensitises mice to the striatal dopamine release enhancing effect of acute morphine (1994) (4)
- The inhibition of the uptake of monoamines by blood platelets by phenothiazines and other drugs. (1974) (4)
- Effect of prenylamine on locomotor activity and brain monoamine levels in mice. (2009) (4)
- 5-Hydroxytryptamine in the blood platelets of cirrhotic and hypertensive patients (1974) (4)
- Naloxonazine reveals the role of μ1-opioid receptor in the rewarding effects of morphine (1994) (3)
- ALCOHOL-PREFERRING AA RATS EXPRESS ENHANCED SENSITIVITY TO STIMULATORY EFFECTS OF MORPHINE (1995) (3)
- The fall of homovanillic acid and 5-hydroxyindoleacetic acid concentrations in brains of mice withdrawn from repeated morphine treatment and their restoration by acute morphine administration (2005) (3)
- Effects of monoamine uptake inhibitors given early postnatally on monoamines in the brain stem, caudate/putamen and cortex, and on dopamine D1 and D2 receptors in the caudate/putamen (2005) (3)
- Channel-linked receptors--from subunits to novel drug targets. (1999) (2)
- 647 – EFFECT OF ANTICHOLINERGICS AND CHOLINOMIMETICS ON MORPHINE-CATALEPSY IN RATS (1977) (2)
- Inhibition of blood platelet monoamine uptake by analgesics. (1970) (1)
- REPEATED MORPHINE TREATMENT INDUCES TOLERANCE TO THE INHIBITORY EFFECT OF MORPHINE ON STRIATAL DOPAMINE RELEASE (1995) (1)
- Comparative studies on the dependence liability of morphine hydrochloride, codeine phosphate and two novel antitussive compounds vadocaine hydrochloride and N-(2',4'-dimethyl-6'-methoxyphenyl)-4-(diethylamine) butanamide hydrochloride in mice. (1988) (1)
- Role of dopamine receptors in the dual effect of naloxone on quinpirole-induced yawning in morphine pretreated rats (1993) (1)
- 5-Hydroxytryptamine in platelets and brain of rabbits treated chronically with imipramine, morphine or methadone (2004) (1)
- Effects of a 5-HT3 receptor antagonist, MDL-72222, on morphine and cocaine stimulated elevation of extracellular dopamine (1994) (1)
- 1009 – EFFECT OF DRUGS ON STRIATAL HOMOVANILLIC ACID CONTENT IN DEVELOPING MICE (1977) (1)
- DOSE-DEPENDENT DECREASE OF DOPAMINE RELEASE IN THE STRIATUM BY INTRASTRIATAL MORPHINE (1995) (1)
- A56 CONSTITUTIVE RET RECEPTOR TYROSINE KINASE ACTIVITY LEADS TO INCREASED CEREBRAL CONCENTRATION OF DOPAMINE AND TO ENHANCEMENT OF COCAINE-INDUCED LOCOMOTOR ACTIVITY IN TRANSGENIC MEN2B MICE (2005) (0)
- Contents, Vol. 9, 1973 (1973) (0)
- Augmented effect of morphine on cerebral dopamine release during withdrawal from chronic morphine treatment (1994) (0)
- Authors’ Index Vol. 9, 1973 (1973) (0)
- Lead administration during gestation and suckling transiently elevates taurine concentration in the brain of developing rats. (1985) (0)
- Behaviour of mice after combination of chlorpromazine with its sulphoxide or with a ATERNARY PHENOTHIAZINE DERIVATIVE (Aprobit). (1968) (0)
- Striatal dopamine metabolism and effects of morphine test dose in mice during withdrawal from chronic morphine treatment (1990) (0)
- Mice display responses of cerebral noradrenaline metabolism to morphine administration different from those of rats (1990) (0)
- EFFECTS OF REPEATED MORPHINE TREATMENT ON NIGROSTRIATAL DOPAMINE RELEASE IN ALCOHOL‐PREFERRING AA AND ALCOHOL‐AVOIDING ANA RATS (1998) (0)
- Influence of some phenothiazine derivatives and related agents on glucose oxidation and 5-hydroxytryptamine content in blood platelets. (1968) (0)
- B30 MORPHINE-INDUCED CONDITIONED PLACE PREFERENCE IN HETEROZYGOUS GDNF KNOCKOUT MICE (2005) (0)
- 786 – AGE-DEPENDENCY OF BRAIN NORADRENALINE CONTENT AND KIDNEY RENIN ACTIVITY IN SPONTANEOUSLY HYPERTENSIVE RATS (1977) (0)
- O2 THE STRIATAL DELTAFOSB EXPRESSION AFTER 4-DAY COCAINE TREATMENT IN ALCOHOL-PREFERRING AA AND ALCOHOL-AVOIDING ANA RATS (2005) (0)
- Subject Index Vol. 9, 1973 (1973) (0)
- Effects of repeated morphine on metabolism of dopamine and serotonin in alcohol-preferring AA and alcohol-avoiding ANA rats (2001) (0)
- 646 – EFFECT OF NARCOTIC ANALGESICS ON THE HOMOVANILLIC ACID CONTENT OF MOUSE STRIATUM (1977) (0)
- Effects of acute morphine on metabolism of dopamine in dorsal striatum of heterozygous GDNF knockout mice (2003) (0)
- Effect of chlorpromazine and desmonomethyl-chlorpromazine on tissue monoamines. (1968) (0)
- Comparison of the central nervous system actions of taurine and N-pivaloyltaurine [proceedings]. (1979) (0)
- 179 – BRAIN MONOAMINES IN ALCOHOL SELECTION AND DEPENDENCE (1977) (0)
- A115 EFFECTS OF MORPHINE AND COCAINE ON LOCOMOTOR ACTIVITY IN NICOTINE-WITHDRAWN MICE (2005) (0)
- Comparison of chlorothiazide, acetazolamide, furosemide and ethacrynic acid in student laboratory exercise. (1967) (0)
- Effect of ganglionic stimulants and sympatholytic drugs on white mice. Weight gain, body fats and noradrenaline content of tissues after the chronic administration of nicotine, dimethylphenylpiperazine, phentolamine and dichloroisoprenaline. (1966) (0)
- Effect of some phenothiazines on the metabolism of red blood cells of rabbit. (1966) (0)
- Effect of probenecid on dopamine metabolites of pigeon brain. (1969) (0)
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