Linda Columbus
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Chemist and researcher
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Linda Columbuschemistry Degrees
Chemistry
#5576
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#6779
Historical Rank
Organic Chemistry
#1064
World Rank
#1202
Historical Rank
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Chemistry
Why Is Linda Columbus Influential?
(Suggest an Edit or Addition)According to Wikipedia, Linda Columbus is an American chemist who is Professor of Chemistry and Molecular Physiology at the University of Virginia. Her research considers the structure-function properties of membrane proteins.
Linda Columbus's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- A new spin on protein dynamics. (2002) (375)
- Endothelial cell expression of hemoglobin α regulates nitric oxide signaling (2012) (235)
- Molecular motion of spin labeled side chains in alpha-helices: analysis by variation of side chain structure. (2001) (232)
- Size and shape of detergent micelles determined by small-angle X-ray scattering. (2007) (218)
- Dependence of Micelle Size and Shape on Detergent Alkyl Chain Length and Head Group (2013) (190)
- Identification of a novel mitochondrial uncoupler that does not depolarize the plasma membrane. (2014) (147)
- The COMBREX Project: Design, Methodology, and Initial Results (2013) (137)
- Mapping backbone dynamics in solution with site-directed spin labeling: GCN4-58 bZip free and bound to DNA. (2004) (117)
- Structure of the KcsA potassium channel from Streptomyces lividans: a site-directed spin labeling study of the second transmembrane segment. (1999) (114)
- MAPK phosphorylation of connexin 43 promotes binding of cyclin E and smooth muscle cell proliferation (2012) (87)
- Endothelial nitric oxide synthase in the microcirculation (2015) (86)
- Protein global fold determination using site‐directed spin and isotope labeling (2008) (82)
- Mixing and matching detergents for membrane protein NMR structure determination. (2009) (68)
- Structural origins of nitroxide side chain dynamics on membrane protein α-helical sites. (2010) (61)
- Hemoglobin &agr;/eNOS Coupling at Myoendothelial Junctions Is Required for Nitric Oxide Scavenging During Vasoconstriction (2014) (52)
- Expression, purification, and characterization of Thermotoga maritima membrane proteins for structure determination (2006) (51)
- Structure of the Neisserial Outer Membrane Protein Opa60: Loop Flexibility Essential to Receptor Recognition and Bacterial Engulfment (2014) (51)
- Conformation transitions of the polypeptide-binding pocket support an active substrate release from Hsp70s (2017) (46)
- Known structure, unknown function: An inquiry‐based undergraduate biochemistry laboratory course (2015) (40)
- Physical determinants of β-barrel membrane protein folding in lipid vesicles. (2011) (39)
- Cottrell Scholars Collaborative New Faculty Workshop: Professional Development for New Chemistry Faculty and Initial Assessment of Its Efficacy (2014) (39)
- Opa+ Neisseria gonorrhoeae exhibits reduced survival in human neutrophils via Src family kinase‐mediated bacterial trafficking into mature phagolysosomes (2015) (31)
- Low- q Bicelles Are Mixed Micelles. (2018) (28)
- Hemoglobin α in the blood vessel wall. (2014) (27)
- Structure of the GLD-1 homodimerization domain: insights into STAR protein-mediated translational regulation. (2010) (26)
- Throwing Away the Cookbook: Implementing Course-Based Undergraduate Research Experiences (CUREs) in Chemistry (2017) (23)
- Modulating Vascular Hemodynamics With an Alpha Globin Mimetic Peptide (Hb&agr;X) (2016) (20)
- Heterocellular contact can dictate arterial function (2019) (20)
- Mixing and Matching Detergents for Membrane Protein NMR Structure Determination (2009) (19)
- Tuning micelle dimensions and properties with binary surfactant mixtures. (2014) (19)
- Post-expression strategies for structural investigations of membrane proteins. (2015) (17)
- Analysis of small-angle X-ray scattering data of protein-detergent complexes by singular value decomposition (2007) (17)
- Neisserial Opa Protein-CEACAM Interactions: Competition for Receptors as a Means of Bacterial Invasion and Pathogenesis. (2016) (15)
- Solution NMR resonance assignment strategies for β‐barrel membrane proteins (2013) (11)
- A broad specificity nucleoside kinase from Thermoplasma acidophilum (2013) (9)
- Label-free method for cell counting in crude biological samples via paramagnetic bead aggregation. (2013) (8)
- Identification and removal of nitroxide spin label contaminant: Impact on PRE studies of α‐helical membrane proteins in detergent (2012) (7)
- Structure and ligand binding of the soluble domain of a Thermotoga maritima membrane protein of unknown function TM1634 (2008) (7)
- NMR structure determination of the conserved hypothetical protein TM1816 from Thermotoga maritima (2005) (7)
- The role of globins in cardiovascular physiology. (2021) (7)
- Quantifying Carcinoembryonic Antigen-like Cell Adhesion Molecule-Targeted Liposome Delivery Using Imaging Flow Cytometry. (2019) (6)
- Mapping membrane protein backbone dynamics: a comparison of site-directed spin labeling with NMR 15N-relaxation measurements. (2014) (6)
- Solution NMR Structure Determination of Polytopic α-Helical Membrane Proteins: A Guide to Spin Label Paramagnetic Relaxation Enhancement Restraints. (2015) (4)
- Refinement of Highly Flexible Protein Structures using Simulation-Guided Spectroscopy. (2018) (4)
- Imaging Flow Cytometry Analysis of CEACAM Binding to Opa‐Expressing Neisseria gonorrhoeae (2020) (3)
- Endothelial alpha globin is a nitrite reductase (2021) (3)
- Variable Expression of Opa Proteins by Neisseria gonorrhoeae Influences Bacterial Association and Phagocytic Killing by Human Neutrophils (2022) (3)
- Human CEACAM1 N-domain dimerization is independent from glycan modifications. (2022) (3)
- Backbone 1H, 13C and 15N resonance assignments of the α-helical membrane protein TM0026 from Thermotoga maritima (2013) (2)
- Site-to-site cross-talk in OST-B glycosylation of hCEACAM1-IgV (2022) (2)
- Conformational dynamics of the membrane enzyme LspA upon antibiotic and substrate binding. (2022) (2)
- Tuning Micelle Dimensions and Properties for Stabilizing Membrane Protein Fold and Function (2015) (1)
- Quantifying CEACAM Targeted Liposome Delivery Using Imaging Flow Cytometry (2019) (1)
- Determining eNOS Binding and Circulation Modulating Effects of an Alpha Globin Mimetic Peptide (HbαX) (2017) (1)
- The Fluidity of Phosphocholine and Maltoside Micelles and the Effect of CHAPS. (2019) (1)
- Insights into the Specificity of Neisserial Opa Protein Interactions with Human Receptors (2015) (1)
- Leading Change in Undergraduate STEM Education (2017) (1)
- TM1385 from Thermotoga maritima functions as a phosphoglucose isomerase via cis-enediol-based mechanism with active site redundancy. (2021) (1)
- Membrane Proteins: Properties (2008) (0)
- Investigating the Relationship Between Physical Properties of Detergents and Membrane Protein Structure Determination (2011) (0)
- Strategy for optimized expression of beta-barrel proteins from pathogenic Gram-negative bacteria to the outer membrane of Escherichia coli (2022) (0)
- Dependence of bicelle segregation on detergent hydrophobic area (2022) (0)
- Molecular Modeling of the Alpha Globin/eNOS Complex via Crosslinking Mass Spectrometry (2019) (0)
- Conformation transitions of the polypeptide-binding pocket support an active substrate release from Hsp70s (2017) (0)
- NMR Solution Structure of Opa60: A Neisserial Membrane Protein that Mediates Host Phagocytosis (2013) (0)
- The NMR solution structure of TM1816 (2004) (0)
- Solving the Structure of Inclusion Membrane Protein a in C. trachomatis (2019) (0)
- Micelles and Bicelles as Membrane Mimics for Membrane Protein Characterization (2016) (0)
- Molecular Determinants of Neissserial Opa Protein Interactions with CEACAM Receptors (2016) (0)
- Molecular Determinants of Neisserial Opa Protein Interactions with Human CEACAMs (2019) (0)
- Guiding Double Electron Electron Resonance Experiments using Information Theory and Molecular Dynamics Simulations (2017) (0)
- Molecular characterisation of the transglycosylases involved in lipopolysaccharide maturation and peptidoglycan biogenesis. (2023) (0)
- Investigating the Conformational Dynamics of the Membrane Enzyme LspA (2019) (0)
- Refinement of Highly Flexible Protein Structures using Simulation‐Guided Spectroscopy (2018) (0)
- Molecular Determinants of Neisserial Pathogenesis: Mapping the Interaction Between Opa I and a Human Binding Partner CEACAM1 (2009) (0)
- NMR structural characterization of the homodimerization domain of the translational repressor GLD‐1 (2008) (0)
- A Novel Conformation of the Polypeptide-Binding Pocket Supports an Active Substrate Release from Hsp70S (2018) (0)
- Faculty Opinions recommendation of Crystal structure of a bacterial homologue of glucose transporters GLUT1-4. (2012) (0)
- Influence of Detergent Properties on the Solubilization and Function of Membrane Proteins (2014) (0)
- Endothelial Pannexin 3 – B Cell Lymphoma‐6 Interactions Protect Against Oxidative Stress (2022) (0)
- Crystal structure of the GLD-1 homodimerization domain from Caenorhabditis elegans N169A mutant at 2.28 A resolution (2010) (0)
- Faculty Opinions recommendation of Massive antibody discovery used to probe structure-function relationships of the essential outer membrane protein LptD. (2019) (0)
- Phosphorylation of the inner core oligosaccharide of lipopolysaccharide mediates recognition and phagocytosis of Gram-negative bacteria by Brain Angiogenesis Inhibitor 1 (BAI1) (2023) (0)
- Probing Conformational Equilibria in Flexible Recognition by Molecular Dynamics and EPR (2016) (0)
- Crystal structure of the GLD-1 homodimerization domain from Caenorhabditis elegans at 2.04 A resolution (2010) (0)
- Impact of Lipid-Protein Interactions on Alpha-Helical Membrane Protein Fold (2019) (0)
- Strategies for the Solution NMR Structure Determination of Beta-Barrel Membrane Proteins (2012) (0)
- A Molecular Model of the Alpha Globin/eNOS Complex (2019) (0)
- Mapping the interface of alpha globin and eNOS: implications for increasing endogenous NO therapeutically (2018) (0)
- SOLUTION STRUCTURE OF OPA60 FROM N. GONORRHOEAE (2014) (0)
- Identification of Key Structural Features Determining the Binding of Alpha Globin and Endothelial Nitric Oxide Synthase (2017) (0)
- Investigating the Catalytic Base Residues in the Phosphoglucose Isomerase From Thermotoga maritima (2019) (0)
- Structure of the soluble domain of the membrane protein TM1634 from Thermotoga maritima (2008) (0)
- Structure, Dynamics, and Receptor Binding of Opa Proteins (2014) (0)
- Rosevear isotope labeling Protein global fold determination using site-directed spin and (2000) (0)
- Molecular Competitors of the Alpha Globin/eNOS Interaction (2016) (0)
- Refinement of highly flexible protein structures using simulation-guided spectroscopy (2018) (0)
- Simulation-Guided Selection of Spectroscopic Experiments to Refine Highly Flexible Protein Structures (2018) (0)
- The Spontaneous Refolding of Opacity-Associated Proteins into Lipid Membranes (2010) (0)
- The Characterization of the Binding of Opacity-Associated Proteins to Human Host Cell Receptors (2011) (0)
- Endothelial nitric oxide synthase in the microcirculation (2015) (0)
- Differences Between Micelles, Bicelles, and Membranes and the Impact on Membrane Protein Structure (2018) (0)
- CRISPR/Cas9 creation of a mouse lacking a unique motif on alpha globin demonstrates its critical role in regulating nitric oxide in vivo (2017) (0)
- Structural Investigations of Inclusion Membrane Protein a (INCA) of Chlamydia Trachomatis (2011) (0)
- Determinants of Opa-CEACAM interactions (2022) (0)
- NMR Solution Structure of Opa60 from N. Gonorrhoeae in FC-12 Micelles (2014) (0)
- Neisseria gonorrhoeae co-opts C4b-binding protein to enhance complement-independent survival from neutrophils (2022) (0)
- Neisserial Opa Protein Loop Dynamics and Mechanism of Interaction with Host CEACAM Receptors (2016) (0)
- Neisserial Opa Protein Dynamics and Interaction with Host Ceacam Receptors (2015) (0)
- NMR Backbone Assignment of Opai: A Mediator of Host:Neisseria Interactions (2011) (0)
- Faculty of 1000 evaluation for Conserved conformational selection mechanism of Hsp70 chaperone-substrate interactions. (2018) (0)
- Backbone 1H, 13C and 15N resonance assignments of the α-helical membrane protein TM0026 from Thermotoga maritima (2012) (0)
- Investigation of Affinities and Structures of Membrane Protein-Protein Interactions using Comparable Samples (2017) (0)
- Nitroxide Spin Label Side Chain Dynamics of Solvent Exposed Sites on Membrane Proteins (2011) (0)
- Conformational Dynamics of the Membrane Enzyme LspA using EPR and MD (2020) (0)
- Targeting Liposomes for Uptake into CEACAM-Expressing Human Cells using a Bacterial Membrane Protein (2016) (0)
- Systematic Perturbations of Micelle Properties to Investigate the Stabilization of Membrane Protein Structure and Function (2015) (0)
- Alpha-Helical Membrane Protein Folding in “Mixed” and “Ideal” Bicelles (2020) (0)
- Modulating the Physical Properties of Micelles for Membrane Protein Investigations (2013) (0)
- The Fluidity of Phosphocholine and Maltoside Micelles and the Effect of CHAPS. (2019) (0)
- Nicole Beno [Exhibition Catalogue] (2016) (0)
- Functional and Structural Studies of Opa Proteins from Neisseria (2020) (0)
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What Schools Are Affiliated With Linda Columbus?
Linda Columbus is affiliated with the following schools:
