Lisa Rohan
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American chemist
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Chemistry
Lisa Rohan's Degrees
- Bachelors Chemistry University of California, Berkeley
Why Is Lisa Rohan Influential?
(Suggest an Edit or Addition)According to Wikipedia, Lisa Cencia Rohan is an American chemist and pharmaceutical scientist. Biography She obtained a Bachelor of Science in chemical engineering from West Virginia University and a Ph.D. in pharmaceutics from the University of Pittsburgh, School of Pharmacy. She completed a postdoctoral fellowship in the department of obstetrics, gynecology, and reproductive sciences in the area of mucosal immunology at the University of Pittsburgh. So far, Rohan has 169 publications with over 3,000 citations. Prior to her academic career, Rohan held leadership positions in the pharmaceutical industry.
Lisa Rohan's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- In Vitro and Ex Vivo Testing of Tenofovir Shows It Is Effective As an HIV-1 Microbicide (2010) (190)
- Vaginal Drug Delivery Systems for HIV Prevention (2009) (167)
- Epigallocatechin Gallate Inactivates Clinical Isolates of Herpes Simplex Virus (2008) (154)
- The Formulated Microbicide RC-101 Was Safe and Antivirally Active Following Intravaginal Application in Pigtailed Macaques (2010) (135)
- Targeted Delivery of PSC-RANTES for HIV-1 Prevention using Biodegradable Nanoparticles (2009) (133)
- Advances in development, scale-up and manufacturing of microbicide gels, films, and tablets. (2010) (120)
- Progress in antiretroviral drug delivery using nanotechnology (2010) (116)
- Glycosidase and Proteinase Activity of Anaerobic Gram-Negative Bacteria Isolated From Women With Bacterial Vaginosis (2003) (103)
- Development and characterization of a vaginal film containing dapivirine, a non-nucleoside reverse transcriptase inhibitor (NNRTI), for prevention of HIV-1 sexual transmission (2011) (102)
- Is Wetter Better? An Evaluation of Over-the-Counter Personal Lubricants for Safety and Anti-HIV-1 Activity (2012) (97)
- Sentinel lymph node biopsy in early-stage cervical cancer: utility of intraoperative versus postoperative assessment. (2008) (94)
- Griffithsin Protects Mice from Genital Herpes by Preventing Cell-to-Cell Spread (2013) (92)
- Nanoparticle-based vaginal drug delivery systems for HIV prevention (2010) (84)
- Reformulated tenofovir gel for use as a dual compartment microbicide. (2012) (78)
- Degradation of naturally occurring and engineered antimicrobial peptides by proteases. (2011) (72)
- Vaginal Mucosa Serves as an Inductive Site for Tolerance1 (2000) (69)
- Preclinical Safety Assessments of UC781 Anti-Human Immunodeficiency Virus Topical Microbicide Formulations (2007) (69)
- 4′-Ethynyl-2-fluoro-2′-deoxyadenosine (EFdA) Inhibits HIV-1 Reverse Transcriptase with Multiple Mechanisms* (2014) (69)
- Design of Poly(lactic-co-glycolic Acid) (PLGA) Nanoparticles for Vaginal Co-Delivery of Griffithsin and Dapivirine and Their Synergistic Effect for HIV Prophylaxis (2019) (64)
- Vaginal Microbicide Gel for Delivery of IQP-0528, a Pyrimidinedione Analog with a Dual Mechanism of Action against HIV-1 (2011) (62)
- Vaginal Film Drug Delivery of the Pyrimidinedione IQP-0528 for the Prevention of HIV Infection (2012) (61)
- PEG-derivatized embelin as a dual functional carrier for the delivery of paclitaxel. (2012) (61)
- A Phase 1 Trial to Assess the Safety, Acceptability, Pharmacokinetics, and Pharmacodynamics of a Novel Dapivirine Vaginal Film (2016) (60)
- Structural basis of HIV inhibition by translocation-defective RT inhibitor 4′-ethynyl-2-fluoro-2′-deoxyadenosine (EFdA) (2016) (59)
- A Phase 1 Randomized, Open Label, Rectal Safety, Acceptability, Pharmacokinetic, and Pharmacodynamic Study of Three Formulations of Tenofovir 1% Gel (the CHARM-01 Study) (2015) (57)
- Digallate Dimers of (−)-Epigallocatechin Gallate Inactivate Herpes Simplex Virus (2011) (55)
- The importance of the vaginal delivery route for antiretrovirals in HIV prevention. (2011) (53)
- Optimization of the Weck-Cel Collection Method for Quantitation of Cytokines in Mucosal Secretions (2000) (51)
- Formulation Development of Retrocyclin 1 Analog RC-101 as an Anti-HIV Vaginal Microbicide Product (2011) (48)
- Inhibition of the transport of HIV in vitro using a pH-responsive synthetic mucin-like polymer system. (2011) (48)
- Nanoassembly of surfactants with interfacial drug-interactive motifs as tailor-designed drug carriers. (2013) (47)
- Increased cerebrospinal fluid levels of GABA, testosterone and estradiol in women with polycystic ovary syndrome (2017) (47)
- Short communication: expression of transporters and metabolizing enzymes in the female lower genital tract: implications for microbicide research. (2013) (44)
- Formulation and Characterization of Polymeric Films Containing Combinations of Antiretrovirals (ARVs) for HIV Prevention (2015) (44)
- Effects of physiological fluids on physical-chemical characteristics and activity of topical vaginal microbicide products. (2008) (42)
- Characterization of Cyclodextrin Inclusion Complexes of the Anti-HIV Non-Nucleoside Reverse Transcriptase Inhibitor UC781 (2008) (42)
- Vaginal Microbicide Film Combinations of Two Reverse Transcriptase Inhibitors, EFdA and CSIC, for the Prevention of HIV-1 Sexual Transmission (2015) (40)
- Permeability of tritiated water through human cervical and vaginal tissue. (2004) (39)
- Microbicide delivery: formulation technologies and strategies (2008) (38)
- The effects of reproductive hormones on the physical properties of cervicovaginal fluid. (2014) (38)
- Increased Dapivirine Tissue Accumulation through Vaginal Film Codelivery of Dapivirine and Tenofovir (2014) (35)
- Development of a vaginal delivery film containing EFdA, a novel anti-HIV nucleoside reverse transcriptase inhibitor. (2014) (34)
- Rational Design of a Multipurpose Bioadhesive Vaginal Film for Co-Delivery of Dapivirine and Levonorgestrel (2019) (33)
- Cell-Instructive Graphene-Containing Nanocomposites Induce Multinucleated Myotube Formation (2016) (32)
- Rectal microbicides: clinically relevant approach to the design of rectal specific placebo formulations (2011) (30)
- Comparison of Dapivirine Vaginal Gel and Film Formulation Pharmacokinetics and Pharmacodynamics (FAME 02B). (2016) (30)
- Formulation and delivery of microbicides. (2012) (29)
- Development of a liposome microbicide formulation for vaginal delivery of octylglycerol for HIV prevention (2012) (29)
- The Sheep as a Model of Preclinical Safety and Pharmacokinetic Evaluations of Candidate Microbicides (2015) (28)
- Characterization of UC781-Tenofovir Combination Gel Products for HIV-1 Infection Prevention in an Ex Vivo Ectocervical Model (2012) (28)
- Microbicide dosage forms. (2014) (28)
- Core Competencies for Research Training in the Clinical Pharmaceutical Sciences (2011) (27)
- Impact of the griffithsin anti-HIV microbicide and placebo gels on the rectal mucosal proteome and microbiome in non-human primates (2018) (27)
- Nanofibrous composite scaffolds of poly(ester amides) with tunable physicochemical and degradation properties (2015) (26)
- Protection Against Rectal Chimeric Simian/Human Immunodeficiency Virus Transmission in Macaques by Rectal-Specific Gel Formulations of Maraviroc and Tenofovir. (2015) (25)
- Drug transporters in tissues and cells relevant to sexual transmission of HIV: Implications for drug delivery. (2015) (24)
- FAME‐04: A Phase 1 trial to assess the safety, acceptability, pharmacokinetics and pharmacodynamics of film and gel formulations of tenofovir (2018) (24)
- Rectal-Specific Microbicide Applicator: Evaluation and Comparison with a Vaginal Applicator Used Rectally (2014) (22)
- Use of frozen-thawed cervical tissues in the organ culture system to measure anti-HIV activities of candidate microbicides. (2006) (21)
- Preferred Physical Characteristics of Vaginal Film Microbicides for HIV Prevention in Pittsburgh Women (2017) (20)
- Development of HIV-1 Rectal-Specific Microbicides and Colonic Tissue Evaluation (2014) (20)
- Pharmacodynamic Activity of Dapivirine and Maraviroc Single Entity and Combination Topical Gels for HIV-1 Prevention (2015) (20)
- Antiviral activity of retrocyclin RC-101, a candidate microbicide against cell-associated HIV-1. (2012) (20)
- The utility of self-emulsifying oil formulation to improve the poor solubility of the anti HIV drug CSIC (2013) (19)
- Development of rectal enema as microbicide (DREAM): Preclinical progressive selection of a tenofovir prodrug enema (2019) (19)
- Comparison of the Pharmacokinetics and Pharmacodynamics of Single-Dose Tenofovir Vaginal Film and Gel Formulation (FAME 05) (2017) (18)
- Preformulation and stability in biological fluids of the retrocyclin RC-101, a potential anti-HIV topical microbicide (2011) (18)
- Testing of viscous anti-HIV microbicides using Lactobacillus. (2012) (18)
- Measurement of Anti-HIV Activity of Marketed Vaginal Products and Excipients Using a PBMC-Based In Vitro Assay (2004) (18)
- Transient swelling, spreading, and drug delivery by a dissolved anti-HIV microbicide-bearing film. (2013) (18)
- Expression and localization of p-glycoprotein, multidrug resistance protein 4, and breast cancer resistance protein in the female lower genital tract of human and pigtailed macaque. (2014) (17)
- A Phase 1 Randomized, Blinded Comparison of the Pharmacokinetics and Colonic Distribution of Three Candidate Rectal Microbicide Formulations of Tenofovir 1% Gel with Simulated Unprotected Sex (CHARM-02). (2015) (17)
- The Anti‐HIV Microbicide Candidate RC‐101 Inhibits Pathogenic Vaginal Bacteria Without Harming Endogenous Flora or Mucosa (2013) (17)
- Evaluation of Combinations of 4′-Ethynyl-2-Fluoro-2′-Deoxyadenosine with Clinically Used Antiretroviral Drugs (2013) (16)
- Novel Application of Hot Melt Extrusion for the Manufacturing of Vaginal Films Containing Microbicide Candidate Dapivirine (2019) (16)
- Impact of Q-Griffithsin anti-HIV microbicide gel in non-human primates: In situ analyses of epithelial and immune cell markers in rectal mucosa (2019) (15)
- Hypo-osmolar Formulation of Tenofovir (TFV) Enema Promotes Uptake and Metabolism of TFV in Tissues, Leading to Prevention of SHIV/SIV Infection (2017) (15)
- Vaginal film for prevention of HIV: using visual and tactile evaluations among potential users to inform product design (2018) (15)
- On-demand microbicide products: design matters (2017) (15)
- Incorporation of the HIV-1 Microbicide Cyanovirin-N in a Food Product (2011) (15)
- In vitro transport characteristics of EFdA, a novel nucleoside reverse transcriptase inhibitor using Caco-2 and MDCKII cell monolayers. (2014) (14)
- Label-free analysis of tenofovir delivery to vaginal tissue using co-registered confocal Raman spectroscopy and optical coherence tomography (2017) (14)
- Preformulation studies of EFdA, a novel nucleoside reverse transcriptase inhibitor for HIV prevention (2014) (14)
- Physiologically‐based pharmacokinetic model of vaginally administered dapivirine ring and film formulations (2018) (14)
- Preformulation and Vaginal Film Formulation Development of Microbicide Drug Candidate CSIC for HIV Prevention (2017) (14)
- Intravenous Formulation of N-Hydroxy-N′-(4-n-butyl-2-methylphenyl)formamidine (HET0016) for Inhibition of Rat Brain 20-Hydroxyeicosatetraenoic Acid Formation (2008) (13)
- Simultaneous Evaluation of Safety, Acceptability, Pericoital Kinetics, and Ex Vivo Pharmacodynamics Comparing Four Rectal Microbicide Vehicle Candidates. (2015) (13)
- A Compensatory Mutation Provides Resistance to Disparate HIV Fusion Inhibitor Peptides and Enhances Membrane Fusion (2013) (12)
- Pharmacodynamic correlations using fresh and cryopreserved tissue following use of vaginal rings containing dapivirine and/or maraviroc in a randomized, placebo controlled trial (2016) (12)
- Mycophenolic Acid for Topical Immunosuppression in Vascularized Composite Allotransplantation: Optimizing Formulation and Preliminary Evaluation of Bioavailability and Pharmacokinetics (2018) (12)
- Expression, regulation, and function of drug transporters in cervicovaginal tissues of a mouse model used for microbicide testing. (2016) (12)
- Retrocyclin RC-101 Blocks HIV-1 Transmission Across Cervical Mucosa in an Organ Culture (2012) (12)
- Nanocrystal Formulation Improves Vaginal Delivery of CSIC for HIV Prevention (2019) (11)
- The Effect of Commonly Used Excipients on the Epithelial Integrity of Human Cervicovaginal Tissue. (2016) (10)
- Vaginal Product Formulation Alters the Innate Antiviral Activity and Glycome of Cervicovaginal Fluids with Implications for Viral Susceptibility. (2018) (9)
- Biorelevant and Screening Dissolution Methods for Minocycline Hydrochloride Microspheres Intended for Periodontal Administration. (2021) (8)
- Vaginal Microbicide Films (2014) (8)
- Rectal pre-exposure prophylaxis (PrEP). (2013) (8)
- Self-assembly of multi-scale anisotropic hydrogels through interfacial polyionic complexation. (2020) (8)
- Inactivation of Herpes Simplex Virus Clinical Isolates by Using a Combination Microbicide (2006) (7)
- Cryopreservation of human mucosal tissues (2018) (7)
- Delineating the Effects of Hot-Melt Extrusion on the Performance of a Polymeric Film using Artificial Neural Networks and an Evolutionary Algorithm. (2019) (6)
- Graduate Education and Research at the University of Pittsburgh (GEAR-UP): A Program to Educate Students about Pharmaceutical Research (2005) (6)
- Assessing the potential of the Woman's Condom for vaginal drug delivery. (2015) (6)
- P2-S9.06 Vaginal film microbicides for HIV prevention: a mixed methods study of women's preferences (2011) (6)
- Preventing the sexual transmission of HIV-1 with topical microbicides: another piece of the equation. (2007) (5)
- Preformulation Characterization of Griffithsin, a Biopharmaceutical Candidate for HIV Prevention (2021) (5)
- Time-resolved imaging refractometry of microbicidal films using quantitative phase microscopy. (2011) (4)
- Susceptibility of Chlamydia trachomatis to Excipients Commonly Used in Topical Microbicide Formulations (2004) (4)
- Analysis of Vaginal Microbicide Film Hydration Kinetics by Quantitative Imaging Refractometry (2014) (4)
- A thermodynamic study of the cyclodextrin-UC781 inclusion complex using a HPLC method (2012) (3)
- A Quantitative Disintegration Method for Polymeric Films (2018) (3)
- Expression, activity, and regulation of phosphorylating enzymes in tissues and cells relevant to HIV-1 sexual transmission. (2021) (3)
- 2519 (2017) (2)
- Comparative Expression Analysis of Cytochrome P450 1A1, Cytochrome P450 1B1 and Nuclear Receptors in the Female Genital and Colorectal Tissues of Human and Pigtailed Macaque (2016) (2)
- P3.365 Tenofovir Vaginal Film: Safety Assessment in the Macaque Model (2013) (2)
- Drug delivery strategies for management of women’s health issues in the upper genital tract (2021) (2)
- A Randomized, Open Label, Crossover Phase 1 Safety and Pharmacokinetic Study of Oral Maraviroc and Maraviroc 1% Gel (the CHARM-03 Study). (2021) (2)
- Development, Characterization and In Vivo Pharmacokinetic Assessment of Rectal Suppositories Containing Combination Antiretroviral Drugs for HIV Prevention (2021) (1)
- Impact of Microbicide Formulation on Glycosylation and Innate Immunity in Cervicovaginal Fluid (2016) (1)
- Vaginal Microbicide Film Combinations of Two Reverse Transcriptase Inhibitors, EFdA and CSIC, for the Prevention of HIV-1 Sexual Transmission (2015) (1)
- A Phase 1a/1b Clinical Trial Design to Assess Safety, Acceptability, Pharmacokinetics and Tolerability of Intranasal Q-Griffithsin for COVID-19 Prophylaxis (2022) (1)
- Investigating the Contribution of Drug-Metabolizing Enzymes in Drug-Drug Interactions of Dapivirine and Miconazole (2021) (1)
- The role of volume in the perceptibility of topical vaginal formulations: User sensory perceptions and experiences (USPEs) of heterosexual couples during vaginal sex. (2020) (1)
- Formulation and Characterization of Polymeric Films Containing Combinations of Antiretrovirals (ARVs) for HIV Prevention (2014) (0)
- Colposcopy of the cervicovagina reveals no adverse effects of RC-101 films. (2013) (0)
- Preferred Physical Characteristics of Vaginal Film Microbicides for HIV Prevention in Pittsburgh Women (2016) (0)
- WITHDRAWN: Delineating the Effects of Hot-Melt Extrusion on the Performance of a Polymeric Film using Artificial Neural Networks and an Evolutionary Algorithm (2019) (0)
- EffEcts of AbnormAl VAginAl florA And mEnoPAusE on cErVicoVAginAl fluid Viscosity doi:10.1136/sextrans-2013-051184.0246 (2013) (0)
- Preformulation and Vaginal Film Formulation Development of Microbicide Drug Candidate CSIC for HIV Prevention (2017) (0)
- On-demand microbicide products: design matters (2017) (0)
- A Quantitative Disintegration Method for Polymeric Films (2018) (0)
- 2519: A quantitative disintegration method to evaluate polymeric films (2017) (0)
- 45A: TARGETED SITE SPECIFIC IMMUNOSUPPRESSION WITH TOPICAL RAPAMYCIN AND MYCOPHENOLIC ACID IN COMPOSITE TISSUE ALLOTRANSPLANTATION (2010) (0)
- for Tolerance Vaginal Mucosa Serves as an Inductive Site (2000) (0)
- Antiviral lectin Q-Griffithsin suppresses fungal infection in murine models of vaginal candidiasis (2022) (0)
- Impact of the griffithsin anti-HIV microbicide and placebo gels on the rectal mucosal proteome and microbiome in non-human primates (2018) (0)
- P1.025 Effects of Abnormal Vaginal Flora and Menopause on Cervicovaginal Fluid Viscosity (2013) (0)
- Cell-Instructive Graphene-Containing Nanocomposites Induce Multinucleated Myotube Formation (2016) (0)
- The effects of reproductive hormones on the viscosity and PH of cervicovaginal fluid (2013) (0)
- Pharmacodynamic Activity of Dapivirine and Maraviroc Single Entity and Combination Topical Gels for HIV-1 Prevention (2015) (0)
- Vaginal Film Drug Delivery of the Pyrimidinedione IQP-0528 for the Prevention of HIV Infection (2012) (0)
- Hypo-osmolar rectal douche tenofovir formulation prevents simian/human immunodeficiency virus acquisition in macaques (2022) (0)
- Charlene Susan Dezzutti (1964-2018) Virologist with a Passion for HIV Prevention. (2018) (0)
- Development and Evaluation of Nanoparticles-in-Film Technology to Achieve Extended In Vivo Exposure of MK-2048 for HIV Prevention (2022) (0)
- The Development of Rectal Microbicides for HIV-1 Prevention (2014) (0)
- Transport and Permeation Properties of Dapivirine: Understanding Potential Drug-Drug Interactions (2022) (0)
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