Lloyd F. Mayer

Q: What Schools Are Affiliated With Lloyd F. Mayer

Lloyd F. Mayer is affiliated with the following schools: Icahn School of Medicine at Mount Sinai, Rockefeller University, University of North Carolina at Chapel Hill

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Lloyd F. Mayer

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Philosophy

Lloyd F. Mayer's Degrees

Bachelors Biology University of Pennsylvania

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Lloyd F. Mayer's Published Works

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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Maintenance infliximab for Crohn's disease: the ACCENT I randomised trial (2002) (3884)
A Short-Term Study of Chimeric Monoclonal Antibody cA2 to Tumor Necrosis Factor α for Crohn's Disease (1997) (2858)
Elevated circulating levels of tumor necrosis factor in severe chronic heart failure. (1990) (2616)
Infliximab for the treatment of fistulas in patients with Crohn's disease. (1999) (2254)
A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease. Crohn's Disease cA2 Study Group. (1997) (1359)
Efficacy and safety of retreatment with anti-tumor necrosis factor antibody (infliximab) to maintain remission in Crohn's disease. (1999) (1065)
Comparison of scheduled and episodic treatment strategies of infliximab in Crohn's disease. (2004) (969)
Anti-interleukin-12 antibody for active Crohn's disease. (2004) (721)
Incidence and importance of antibody responses to infliximab after maintenance or episodic treatment in Crohn's disease. (2004) (640)
Toll-like receptors on tumor cells facilitate evasion of immune surveillance. (2005) (525)
Evidence for function of Ia molecules on gut epithelial cells in man (1987) (500)
Mucus Enhances Gut Homeostasis and Oral Tolerance by Delivering Immunoregulatory Signals (2013) (486)
The Incidence and Management of Infusion Reactions to Infliximab: A Large Center Experience (2003) (462)
Infliximab in the Treatment of Severe, Steroid-Refractory Ulcerative Colitis: A Pilot Study (2001) (432)
Oral tolerance and its relation to food hypersensitivities. (2005) (388)
Crosstalk between B lymphocytes, microbiota and the intestinal epithelium governs immunity versus metabolism in the gut (2011) (321)
Antigen processing and presentation by intestinal epithelial cells - polarity and complexity. (2000) (319)
Tacrolimus for the treatment of fistulas in patients with Crohn's disease: a randomized, placebo-controlled trial. (2003) (316)
Characterization of interleukin-17-producing regulatory T cells in inflamed intestinal mucosa from patients with inflammatory bowel diseases. (2011) (303)
The natural history of egg allergy in an observational cohort. (2013) (302)
Chromoendoscopy-Targeted Biopsies Are Superior to Standard Colonoscopic Surveillance for Detecting Dysplasia in Inflammatory Bowel Disease Patients: A Prospective Endoscopic Trial (2008) (294)
Expression of class II molecules on intestinal epithelial cells in humans. Differences between normal and inflammatory bowel disease. (1991) (267)
The natural history of milk allergy in an observational cohort. (2013) (263)
Recent understanding of IBD pathogenesis: Implications for future therapies (2006) (245)
Interleukin 10 suppresses Th17 cytokines secreted by macrophages and T cells (2008) (232)
American gastroenterological association consensus development conference on the use of biologics in the treatment of inflammatory bowel disease, June 21-23, 2006. (2007) (226)
The Immune Response in Inflammatory Bowel Disease (2007) (220)
CD4+NKG2D+ T cells in Crohn's disease mediate inflammatory and cytotoxic responses through MICA interactions. (2007) (210)
Lack of induction of suppressor T cells by intestinal epithelial cells from patients with inflammatory bowel disease. (1990) (209)
Therapeutic potential of oral tolerance (2004) (204)
Evidence for altered regulation of I kappa B alpha degradation in human colonic epithelial cells. (1997) (203)
Diagnosis and treatment of gastrointestinal disorders in patients with primary immunodeficiency. (2013) (201)
Toll-like receptor signaling in small intestinal epithelium promotes B-cell recruitment and IgA production in lamina propria. (2008) (189)
Listeria monocytogenes promotes tumor growth via tumor cell toll-like receptor 2 signaling. (2007) (187)
Immunopathogenesis of inflammatory bowel disease (2002) (183)
Defects in CD8+ Regulatory T Cells in the Lamina Propria of Patients with Inflammatory Bowel Disease 1 (2005) (182)
Enteroendocrine cells express functional Toll-like receptors. (2007) (179)
Inflamed Lymphatic Endothelium Suppresses Dendritic Cell Maturation and Function via Mac-1/ICAM-1-Dependent Mechanism1 (2009) (177)
Selective regulation of cytokine secretion by hydroxychloroquine: inhibition of interleukin 1 alpha (IL-1-alpha) and IL-6 in human monocytes and T cells. (1993) (176)
Constitutive activation of epithelial TLR4 augments inflammatory responses to mucosal injury and drives colitis‐associated tumorigenesis (2011) (174)
Expansion of CD8+ T cells with regulatory function after interaction with intestinal epithelial cells. (2002) (170)
Evolving paradigms in the pathogenesis of IBD (2009) (168)
Monoclonal antibodies, immunogenicity, and associated infusion reactions. (2005) (164)
Failure to induce oral tolerance to a soluble protein in patients with inflammatory bowel disease. (2004) (161)
Anti-IP-10 antibody (BMS-936557) for ulcerative colitis: a phase II randomised study (2013) (159)
The expression and function of costimulatory molecules B7H and B7-H1 on colonic epithelial cells. (2004) (159)
A functional genomics predictive network model identifies regulators of inflammatory bowel disease (2017) (157)
A novel Toll-like receptor 4 antagonist antibody ameliorates inflammation but impairs mucosal healing in murine colitis. (2009) (156)
A Genome-Wide Scan of Ashkenazi Jewish Crohn's Disease Suggests Novel Susceptibility Loci (2012) (148)
IRF-8/Interferon (IFN) Consensus Sequence-binding Protein Is Involved in Toll-like Receptor (TLR) Signaling and Contributes to the Cross-talk between TLR and IFN-γ Signaling Pathways* (2006) (145)
CD1d is involved in T cell-intestinal epithelial cell interactions (1993) (145)
Pathogenesis and treatment of gastrointestinal disease in antibody deficiency syndromes. (2009) (145)
The regulation and functional consequence of proinflammatory cytokine binding on human intestinal epithelial cells. (1998) (143)
Accumulation of peripheral autoreactive B cells in the absence of functional human regulatory T cells. (2013) (142)
Colonic epithelial cells are a major site of macrophage inflammatory protein 3α (MIP-3α) production in normal colon and inflammatory bowel disease (2002) (141)
AP-1 Activated by Toll-like Receptors Regulates Expression of IL-23 p19* (2009) (139)
Evidence for a defect in "switch" T cells in patients with immunodeficiency and hyperimmunoglobulinemia M. (1986) (132)
Characterization of immunologic defects in patients with common variable immunodeficiency (CVID) with intestinal disease (2011) (128)
A phase I study of visilizumab, a humanized anti-CD3 monoclonal antibody, in severe steroid-refractory ulcerative colitis. (2007) (121)
Inhibition of human immunodeficiency virus type 1 replication by hydroxychloroquine in T cells and monocytes. (1993) (121)
Transcription factor IRF8 directs a silencing programme for TH17 cell differentiation (2011) (120)
Epithelia: lymphocyte interactions in the gut (2007) (118)
Regulatory T Cells: Peace Keepers in the Gut (2004) (118)
Evidence for accessory cell function by class II MHC antigen-expressing airway epithelial cells. (1991) (115)
Activation of CD8+ Regulatory T Cells by Human Placental Trophoblasts1 (2005) (108)
Lung dendritic cells induce migration of protective T cells to the gastrointestinal tract (2013) (108)
Human T cell hybridomas secreting factors for IgA-specific help, polyclonal B cell activation, and B cell proliferation (1982) (107)
The role of epithelial cells in immune regulation in the gut. (2001) (107)
Induction of mucosal tolerance in Peyer's patch-deficient, ligated small bowel loops. (2005) (106)
The cytomegalovirus-encoded chemokine receptor US28 promotes intestinal neoplasia in transgenic mice. (2010) (105)
T cell antigen receptor V gene usage. Increases in V beta 8+ T cells in Crohn's disease. (1990) (105)
MicroRNA-7 Modulates CD98 Expression during Intestinal Epithelial Cell Differentiation* (2009) (101)
Development of an internet‐based cohort of patients with inflammatory bowel diseases (CCFA Partners): Methodology and initial results (2011) (101)
Mucosal immunity and gastrointestinal antigen processing. (2000) (98)
Expression of nonclassical class I molecules by intestinal epithelial cells (2007) (97)
Expression of class II molecules on intestinal epithelial cells in humans (1991) (96)
Immunologic features of infants with milk or egg allergy enrolled in an observational study (Consortium of Food Allergy Research) of food allergy. (2010) (95)
Epstein‐Barr virus‐induced gene 3 negatively regulates IL‐17, IL‐22 and RORγt (2008) (94)
CD5 and immunoglobulin V gene expression in B-cell lymphomas and chronic lymphocytic leukemia. (1990) (87)
Stimulation of lamina propria lymphocytes by intestinal epithelial cells: evidence for recognition of nonclassical restriction elements (1994) (86)
Intestinal epithelial cells from inflammatory bowel disease patients preferentially stimulate CD4+ T cells to proliferate and secrete interferon-gamma. (2007) (81)
Anti-CD3 antibody visilizumab is not effective in patients with intravenous corticosteroid-refractory ulcerative colitis (2010) (81)
Normal Response to Vaccines in Inflammatory Bowel Disease Patients Treated with Thiopurines (2012) (80)
Allergic sensitization can be induced via multiple physiologic routes in an adjuvant-dependent manner. (2011) (79)
The intestinal epithelial cell: processing and presentation of antigen to the mucosal immune system (1999) (78)
Human malignant T cells capable of inducing an immunoglobulin class switch (1985) (77)
Human intestinal epithelial cell-induced CD8+ T cell activation is mediated through CD8 and the activation of CD8-associated p56lck (1995) (77)
Complex Formation of the Interferon (IFN) Consensus Sequence-binding Protein with IRF-1 Is Essential for Murine Macrophage IFN-γ-induced iNOS Gene Expression* (2003) (76)
Lidocaine inhibits secretion of IL‐8 and IL‐1β and stimulates secretion of IL‐1 receptor antagonist by epithelial cells (2002) (75)
Synthesis and regulation of accessory/proinflammatory cytokines by intestinal epithelial cells (1995) (74)
Delineation of a CD1d-restricted antigen presentation pathway associated with human and mouse intestinal epithelial cells. (2003) (73)
Colonic epithelial cells are a major site of macrophage inflammatory protein 3alpha (MIP-3alpha) production in normal colon and inflammatory bowel disease. (2002) (73)
Can we produce true tolerance in patients with food allergy? (2013) (71)
CD4 T cells activated in the mesenteric lymph node mediate gastrointestinal food allergy in mice. (2007) (71)
Epithelial: lamina propria lymphocyte interactions promote epithelial cell differentiation. (2008) (68)
Notch-1 signaling regulates intestinal epithelial barrier function, through interaction with CD4+ T cells, in mice and humans. (2011) (67)
Persistent infection of human adenovirus type 5 in human monocyte cell lines. (1992) (67)
Metabolic Alterations to the Mucosal Microbiota in Inflammatory Bowel Disease (2014) (65)
Thymic stromal lymphopoietin is required for gastrointestinal allergy but not oral tolerance. (2010) (64)
Characterization of a 180-kDa Intestinal Epithelial Cell Membrane Glycoprotein, gp180 (1997) (63)
Chromoendoscopy Is More Effective Than Standard Colonoscopy in Detecting Dysplasia During Long-term Surveillance of Patients With Colitis. (2016) (62)
Crohn disease: frequency and nature of CARD15 mutations in Ashkenazi and Sephardi/Oriental Jewish families. (2004) (61)
Occurrence of Clostridium difficile toxin during the course of inflammatory bowel disease (1981) (60)
Early preservation of effector functions followed by eventual T cell memory depletion: a model for the delayed onset of the effect of thiopurines (2008) (60)
High levels of Crohn's disease-associated anti-microbial antibodies are present and independent of colitis in chronic granulomatous disease. (2011) (58)
Infusion reactions and their management. (2006) (58)
Safety and Tolerability of Human Placenta-Derived Cells (PDA001) in Treatment-Resistant Crohn’s Disease: A Phase 1 Study (2013) (57)
Gastrointestinal manifestations in primary immune disorders. (2010) (57)
Prospective randomized open‐label multicenter phase I/II dose escalation trial of visilizumab (HuM291) in severe steroid‐refractory ulcerative colitis† (2010) (54)
Orthotopic tracheal transplantation in the murine model. (2002) (53)
Immunoregulatory lymphokines of T hybridomas from AIDS patients: constitutive and inducible suppressor factors. (1984) (52)
Ubiquitin-dependent Degradation of Interferon Regulatory Factor-8 Mediated by Cbl Down-regulates Interleukin-12 Expression* (2005) (51)
Non‐classical MHC class I molecules on intestinal epithelial cells: mediators of mucosal crosstalk (2005) (50)
Oral tolerance and inflammatory bowel disease (2005) (49)
Evaluation of 22 genetic variants with Crohn's Disease risk in the Ashkenazi Jewish population: a case-control study (2011) (48)
Polyclonal immunoglobulin secretion in patients with common variable immunodeficiency using monoclonal B cell differentiation factors. (1984) (48)
Allergen-IgE complexes trigger CD23-dependent CCL20 release from human intestinal epithelial cells. (2007) (48)
The Nonclassical Class I Molecule CD1d Associates with the Novel CD8 Ligand gp180 on Intestinal Epithelial Cells* (1999) (48)
Extracorporeal photopheresis for the treatment of refractory Crohn's disease: Results of an open‐label pilot study (2009) (47)
Current status of monoclonal antibody therapy for the treatment of inflammatory bowel disease (2010) (46)
Early clinical experience with adalimumab in treatment of inflammatory bowel disease with infliximab‐treated and naïve patients (2009) (44)
Orthotopic tracheal allografts undergo reepithelialization with recipient-derived epithelium. (2003) (44)
Mucosal immunology of tolerance and allergy in the gastrointestinal tract (2012) (44)
Differential expression of interleukin 1 receptor antagonist isoforms in human intestinal epithelial cells. (1998) (44)
Original contributionThe incidence and management of infusion reactions to infliximab: a large center experience (2003) (44)
A single‐arm, open‐label study of alemtuzumab in treatment‐refractory patients with multiple sclerosis (2012) (44)
High-dose infliximab therapy in Crohn's disease: clinical experience, safety, and efficacy. (2015) (42)
The kinetics and pattern of tracheal allograft re-epithelialization. (2003) (42)
Identification of subpopulations of human macrophages through the generation of human macrophage hybridomas. (1990) (41)
Oral tolerance to protein antigens (2001) (40)
Serum protein profiling in patients with inflammatory bowel diseases using selective solid-phase bulk extraction, matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and chemometric data analysis. (2007) (38)
The expression and regulation of class II antigens in normal and inflammatory bowel disease peripheral blood monocytes and intestinal epithelium. (1991) (38)
Evidence for a genetic defect in oral tolerance induction in inflammatory bowel disease (2006) (37)
A functional role for CCR6 on proallergic T cells in the gastrointestinal tract. (2010) (37)
Expression of the chemokine binding protein M3 promotes marked changes in the accumulation of specific leukocytes subsets within the intestine. (2009) (37)
Intestinal heat shock protein 110 regulates expression of CD1d on intestinal epithelial cells. (2003) (36)
IL-13-mediated immunological control of enterochromaffin cell hyperplasia and serotonin production in the gut (2012) (35)
A role for the epidermal growth factor receptor signaling in development of intestinal serrated polyps in mice and humans. (2012) (35)
Review article: Local and systemic regulation of mucosal immunity (1997) (35)
I. Antigen presentation in the intestine: new rules and regulations. (1998) (34)
New proteomic approaches for biomarker discovery in inflammatory bowel disease (2010) (34)
Failure to Induce Oral Tolerance in Crohn's and Ulcerative Colitis Patients: Possible Genetic Risk (2004) (34)
Maintenance infliximab (Remicade) is safe, effective and steroid-sparing in Crohn's disease: Preliminary results from the accent i trial (2001) (34)
T cell antiidiotypic antibodies reveal differences between two human leukemias (1984) (34)
Oral tolerance: new approaches, new problems. (2000) (32)
A humanized anti-CD3 monoclonal antibody, visilizumab, for treatment of severe steroid-refractory ulcerative colitis: Preliminary results of a phase I study (2003) (32)
Extended haplotype association study in Crohn’s disease identifies a novel, Ashkenazi Jewish-specific missense mutation in the NF-κB pathway gene, HEATR3 (2013) (32)
Expression of growth factor receptor-encoded mRNA by colonic epithelial cells is altered in inflammatory bowel diseas (1995) (32)
Oligoclonal expansions of mucosal T cells in Crohn’s disease predominate in NKG2D-expressing CD4 T cells (2013) (32)
Activation of a Unique Population of CD8+ T Cells by Intestinal Epithelial Cells (2004) (31)
Defect in CEACAM family member expression in Crohn's disease IECs is regulated by the transcription factor SOX9 (2009) (31)
Current status of monoclonal antibody therapy for the treatment of inflammatory bowel disease: an update (2013) (31)
CCFA Microbial–Host Interactions Workshop: Highlights and key observations (2007) (30)
Suppression of Th1 and Th17, but not Th2, responses in a CD8+ T cell-mediated model of oral tolerance (2009) (29)
Current concepts in mucosal immunity. I. Antigen presentation in the intestine: new rules and regulations. (1998) (29)
Evidence for an altered T-cell receptor repertoire in Crohn's disease. (1994) (28)
Unique Features of Antigen Presentation in the Intestine a (1992) (28)
15 – Diversity and Function of Antigen-Presenting Cells in Mucosal Tissues (1994) (26)
Oral tolerance : mechanisms and applications (1996) (26)
Cytokine secretion induced by superantigens in peripheral blood mononuclear cells, lamina propria lymphocytes, and intraepithelial lymphocytes (1995) (25)
Antigen Trafficking in the Intestine a (1996) (25)
CLINICAL-ALIMENTARY TRACT A Phase I Study of Visilizumab, a Humanized Anti-CD3 Monoclonal Antibody, in Severe Steroid-Refractory Ulcerative Colitis (2007) (25)
Antigen handling in the intestine mediated by normal enterocytes (1990) (25)
Integrated Analysis of Biopsies from Inflammatory Bowel Disease Patients Identifies SAA1 as a Link Between Mucosal Microbes with TH17 and TH22 Cells (2017) (24)
A multicenter retrospective experience of infliximab in Crohn's disease patients: infusion reaction rates and treatment persistency. (2007) (24)
Use of GM-CSF in the treatment of colitis associated with chronic granulomatous disease. (2005) (23)
Reepithelialization of Orthotopic Tracheal Allografts Prevents Rejection after Withdrawal of Immunosuppression (2005) (23)
Dead on arrival: understanding the failure of CTLA4-immunoglobulin therapy in inflammatory bowel disease. (2012) (22)
Progressive impairment of monocytic function in HIV-1-infected human macrophage hybridomas. (1993) (22)
In vivo detection of a novel macrophage-derived protein involved in the regulation of mucus-like glycoconjugate secretion. (1992) (22)
Inhibition of HIV‐1 productive infection in hepatoblastoma HepG2 cells by recombinant tumor necrosis factor-α (1992) (21)
Factors Affecting Antigen Uptake by Human Intestinal Epithelial Cell Lines (2000) (21)
Mucosal epithelium in health and disease. (2005) (21)
Purification and in vitro growth of human epidermal basal keratinocytes using a monoclonal antibody. (1985) (20)
Mitochondria Influence Fas Expression in GP120-Induced Apoptosis of Neuronal Cells (2009) (20)
Mechanisms underlying inflammatory bowel disease (2006) (20)
The IBD1 locus for susceptibility to Crohn's disease has a greater impact in Ashkenazi Jews with early onset disease (2001) (20)
Mucus secretagogue production by a human macrophage hybridoma. (1991) (19)
Immunomodulatory Roles of the Carcinoembryonic Antigen Family of Glycoproteins (2006) (19)
Oral tolerance: mechanisms and applications. Introduction. (1996) (19)
Intranasal delivery of a protein subunit vaccine using a Tobacco Mosaic Virus platform protects against pneumonic plague. (2016) (18)
Working out mechanisms of controlled/physiologic inflammation in the GI tract (2012) (18)
Synergy between B cell differentiation factors and interleukin 2, using a monoclonal system. (1985) (17)
Regulation of B Cell Activation and Differentiation with Factors Generated by Human T Cell Hybridomas (1984) (17)
Expression of protooncogene-encoded mRNA by colonic epithelial cells in inflammatory bowel disease (1996) (16)
Attenuation of TNF-driven murine ileitis by intestinal expression of the viral immunomodulator CrmD (2010) (16)
Characterization of lymphokines mediating B cell growth and differentiation from monoclonal anti-CD3 antibody-stimulated T cells. (1989) (16)
Characterizing CEACAM5 interaction with CD8α and CD1d in intestinal homeostasis (2013) (16)
Antigen Uptake and Trafficking in Human Intestinal Epithelial Cells (2000) (16)
A novel human macrophage-derived intestinal mucin secretagogue: implications for the pathogenesis of inflammatory bowel disease. (1993) (16)
Enhanced Oral Tolerance in Transgenic Mice with Hepatocyte Secretion of IL-101 (2005) (16)
The role of the epithelium in mucosal immunity. (1997) (16)
Transcription Factor IRF 8 Directs a Silencing Programme for TH 17 Cell Differentiation (2011) (16)
Expression of Blimp-1 in Dendritic Cells Modulates the Innate Inflammatory Response in Dextran Sodium Sulfate-Induced Colitis (2014) (16)
Antigen recognition in the gastrointestinal tract: Death to the dogma (1991) (15)
Terminal maturation of resting B cells by proliferation-independent B cells differentiation factors (1986) (14)
Three dose induction regimen of infliximab (Remicade) is superior to a single dose in patients with Crohns disease (CD) (2001) (14)
A Randomized, Placebo-Controlled Trial of MDX-1100, an Anti-IP-10 Antibody, for Moderately to Severely Active Ulcerative Colitis (2010) (13)
Antigen presentation in the intestine (1991) (12)
Transforming growth factor β signaling controls activities of human intestinal CD8(+)T suppressor cells. (2013) (12)
Epithelial cell antigen presentation (2000) (12)
Anti-inflammatory Effects of the Chinese Herbal Formula FAHF-2 in Experimental and Human IBD (2013) (12)
Resistant hepatic allograft rejection successfully treated with cyclophosphamide and plasmapheresis. (1990) (12)
Natural Killer T Cells in Mucosal Homeostasis (2004) (11)
Oral tolerance: lessons on treatment of food allergy (2005) (11)
Surface expression of CD-4 does not predict susceptibility to infection with HIV-1 in human monocyte hybridomas. (1990) (10)
B cell differentiation factor-induced human B cell maturation: stimulation of intracellular calcium release. (1995) (10)
A novel approach to the treatment of ulcerative colitis: is it kosher? (2005) (10)
Potential non‐T cells source of interleukin‐4 in food allergy (2014) (10)
Human airway epithelial cells stimulate T-lymphocyte lck and fyn tyrosine kinase. (1997) (10)
The Use of Oral Tolerance in the Therapy of Chronic Inflammatory/Autoimmune Diseases (2004) (9)
Differential p38 Mitogen-Activated Protein Kinase Target Phosphorylation in Responders and Nonresponders to Infliximab (2003) (9)
IBD: immunologic research at The Mount Sinai Hospital. (2000) (9)
Impairment of monocytic function during Trypanosoma cruzi infection. (1994) (9)
A membrane protein preferentially expressed by a subpopulation of immature lymphoid cells, epidermal basal keratinocytes, and other epithelial cells. (1985) (9)
The Development of Animal Models of Inflammatory Bowel Disease (2000) (9)
704 A Phase 1 Open-Label, Single-Dose, Dose-Escalation Study of Mdx-1100, a High-Affinity, Neutralizing, Fully Human Igg1κ Anti-CXCL10 (Ip10) Monoclonal Antibody, in Ulcerative Colitis (2008) (8)
Chapter 25 - Role of Epithelial Cells in Mucosal Antigen Presentation (2005) (7)
The Role of Cellular Immunity in Neoplasia (1976) (7)
Shared experiences and best practices in the management of rheumatoid arthritis and Crohn's disease. (2011) (7)
The role of epithelial cells as accessory cells. (1987) (7)
B cell differentiation factor-induced B cell maturation: regulation via reduction in cAMP. (1995) (7)
Impairment of monocytic function after influenza virus infection (1995) (7)
"Immune/Non-immune cell interactions in intestinal inflammation" workshop. (1997) (7)
Mucin Secretion in Inflammatory Bowel Disease: Comparison of a Macrophage‐Derived Mucin Secretagogue (MMS‐68) to Conventional Secretagogues (1998) (7)
Oral tolerance : new insights and prospects for clinical application (2004) (7)
34 – NONHEPATIC GASTROINTESTINAL MANIFESTATIONS OF SYSTEMIC LUPUS ERYTHEMATOSUS (2004) (6)
Chapter 1 – Development and Physiology of Mucosal Defense: An Introduction (2005) (6)
Selective induction of antigen nonspecific suppressor cells with normal gut epithelium as accessory cells. (1988) (6)
Comparative pharmacokinetics of single and multiple-dose infliximab in Crohns disease patients (2002) (6)
Mesalamine (5-aminosalicylic acid) therapy well tolerated in a patient with aspirin hypersensitivity and ulcerative colitis. (2011) (5)
Pathogenesis of inflammatory bowel disease: evolving concepts. (1996) (5)
Nonprofessional Antigen Presentation (1996) (5)
Peace Keepers in the Gut (2004) (5)
Inhibition of HIV-1 productive infection in hepatoblastoma HepG2 cells by recombinant tumor necrosis factor-alpha. (1992) (5)
Expansion of a suppressor T-cell population associated with the hyper-IgM syndrome and generalized lymphadenopathy. (1991) (5)
Regulation of Mucosal Immune Responses: Distinct Antigens and Antigen Presenting Cells (1997) (5)
387 A Placebo-Controlled Trial of Visilizumab in Patients with Intravenous (IV) Steroid Refractory Ulcerative Colitis (UC) (2009) (5)
Rapid generation of human T cell hybridomas. (1985) (5)
Correlation of spontaneous suppressor cell activity with progression of human immunodeficiency virus infection. (1991) (5)
Mucin Secretion in Inflammatory Bowel Disease: Comparison of a Macrophage-Derived Mucin Secretagogue (MMS-68) to Conventional Secretagogues (1998) (4)
Hypogammaglobulinemia with Facial Edema (2006) (4)
Intra-allograft production and systemic release of tumor necrosis factor-alpha: detection upon reperfusion. (1993) (4)
Treatment of disease through oral tolerance. (2004) (4)
Heterogeneity of B cell growth and differentiation factors. (1984) (4)
Meeting Summary: Signal Transduction Pathways in Immune and Inflammatory Cells November 30–December 3, 2000, Amelia Island, Florida, U.S.A. (2003) (4)
The IBD1 locus for susceptibility to Crohn’s disease has a greater impact in Ashkenazi Jews with early onset disease (2001) (4)
2 Antigen presentation in the intestine (1996) (4)
Erratum: Toll-like receptors on tumor cells facilitate evasion of immune surveillance (Cancer Research (June 15, 2005) 65 (5009-5014)) (2005) (3)
Inflammatory bowel diseaseThe incidence and management of acute infusion reactions to infliximab: a large center experience (2001) (3)
Functional toll-like receptors (TLR) are expressed on intestinal epithelial cells (IEC) (2000) (3)
Lymphoepithelial Interactions (2009) (3)
BASIC-ALIMENTARY TRACT CD4NKG2D T Cells in Crohn's Disease Mediate Inflammatory and Cytotoxic Responses Through MICA Interactions (2007) (3)
198 Follow-Up Chromoendoscopy Continues to Be Superior to Standard Colonoscopic Surveillance for Managing Dysplasia in Patients with IBD: A Long-Term, Prospective, Endoscopic Trial (2008) (3)
CHAPTER 52 – Inflammatory Bowel Diseases: Ulcerative Colitis and Crohn's Disease (2006) (3)
Effect of Crohn’s Disease Risk Alleles on Enteric Microbiota Marker Paper (2010) (3)
The role of the epithelial cell in immunoregulation: pathogenetic and therapeutic implications. (1990) (3)
IgA SPECIFIC T‐CELL FACTOR PRODUCED BY A HUMAN T‐T HYBRIDOMA * (1983) (3)
Innate and acquired immunity at mucosal surfaces. (2000) (3)
Role of Epithelial Cells in Antigen Presentation (2015) (3)
The generation and characterization of human monocyte hybridomas. (1991) (3)
What do malaria, rheumatoid arthritis, systemic lupus erythematosus and ulcerative colitis have in common? (1997) (2)
T cell factors regulating B cell activation and differentiation. (1984) (2)
T-cell subsets in multiple sclerosis: Lack of correlation between helper and suppressor T cells and the clinical state (2004) (2)
CD8+regulatory cells are present in normal lamina propria but are lacking in patients with inflammatory bowel disease (2003) (2)
Editor's Note: Toll-Like Receptors on Tumor Cells Facilitate Evasion of Immune Surveillance. (2019) (2)
Immunology of diseases of the oral cavity. Chapter 89. (2005) (2)
Immunologic Features of Infants with Milk or Egg Allergy Enrolled in an Observational Study (CoFAR) of Food Allergy (2010) (2)
Mac-1 / ICAM-1-Dependent Mechanism Dendritic Cell Maturation and Function via Inflamed Lymphatic Endothelium Suppresses and Mihaela (2009) (2)
Purification to homogeneity of a novel human B cell differentiation factor. (1995) (2)
Optimizing Outcomes in Hepatitis C: Is Treatment Beyond 48 Weeks Ever Justified? (2006) (2)
Yin and Yang of mucosal immunology. (1996) (2)
Switch T cell line, ST, induces an Ig class switch in surface isotype. (1987) (2)
Immunology of inflammatory bowel disease (1990) (2)
Interferon-γ and Class II Antigen Expression on Enterocytes (1993) (2)
The role of differential class II antigen expression in stimulation of allogeneic mixed lymphocyte reactions by human monocyte hybridomas. (1992) (1)
CEACAM5 is upregulated with inflammation in Crohnʼs colitis in response to IL-22: P-207. (2011) (1)
Mucosal immunity (2005) (1)
W1250 Early Experience with Adalimumab for the Treatment of IBD in An Academic Medical Center (2008) (1)
Cytokines regulating human B cell growth and differentiation. (1991) (1)
890 Reversibility of Esophageal Fibrosis in Response to Various Therapies in Children with Eosinophilic Esophagitis (2009) (1)
Molecular Regulation of the Human Immunoglobulin γ1 Heavy Chain Gene by IL‐6 (1989) (1)
A novel toll-like receptor 4 (TLR4) antagonist antibody ameliorates inflammation but impairs mucosal healing in murine colitis Running Title: Dual effect of anti-TLR4 antibody in murine colitis (2009) (1)
STIMULATION OF DISTINCT T CELL SUBSETS IN MLR USING HUMAN MACROPHAGE HYBRIDOMAS DIFFERENTIALLY EXPRESSING CLASS II ANTIGENS (1991) (1)
Oral tolerance: boom or bust for autoimmunity. (1996) (1)
Introduction (1996) (1)
Inlammatory bowel diseases: The paradigm for 21st century medicine - Introduction (2004) (1)
Isolation of fibroblast proliferation factor: distinction from interleukin-1. (1987) (1)
High-dose Infliximab in Crohnʼs Disease: Clinical Experience, Safety, and Efficacy: 1675 (2013) (1)
Mucosal Surfaces: Immunological Protection (2006) (1)
The Need for Infliximab Dose Escalation in Ulcerative Colitis: 1189 (2009) (1)
Expression of carcinoembryonic antigen (CEA), like gp180, is reduced in IECS derived from patients with Crohn's disease (2000) (1)
1047 Chromoendoscopy Is Superior to Standard Surveillance Techniques for Both High and Low Risk Patients for the Detection of Dysplasia: Analysis of a Prospective Controlled Trial (2009) (1)
Intestinal lumen-derived heat shock protein 110 regulates expression of the MHC-class I-like molecule CD1d on intestinal epithelial cells (2003) (1)
O-015 Metabolic Alterations to the Mucosal Microbiota of Inflammatory Bowel Disease Patients are Associated with Cd4+ T Cell Homeostasis (2013) (1)
592 Detection of a novel 68,000 d mucus secretagogue by a monoclonal antibody (1991) (1)
Current advances in gastrointestinal immunology. (1993) (1)
C D 5 and Immunoglobulin V Gene Expression in B-Cell Lymphomas and Chronic Lymphocytic Leukemia (2003) (1)
Immune response in inflammatory bowel disease (2009) (1)
Human B cell maturation and immune regulation. (1987) (1)
Human T-cell hybridomas secreting factors for B-cell differentiation and proliferation. (1983) (1)
CEA (Carcinoembryonic antigen) shows identity to gp189 and can modulate mucosal immune responses (2001) (1)
DOP66 A CEACAM5 small peptide restores the suppressive activity of CD8 + T cells in patients with Crohn’s disease (2020) (1)
Inflammatory Bowel Disease Lamina Propria of Patients with Regulatory T Cells in the + Defects in CD8 (2005) (0)
S1680 The Ability of Carcinoembryonic Antigen Cell-Adhesion Molecule Family Members with the Non-Classical Class I Molecule CD1D and CD8 (2009) (0)
X. Challenges update workgroups (2008) (0)
P085 Visilizumab For The Treatment of Subjects With Intravenous Steroid-Refractory Ulcerative Colitis (Ivsr-Uc): Short and Long-Term Disease Response Similar Over Multiple Dose Levels (2007) (0)
Factors Generated by Human T-Cell Hybridomas Regulate B-Cell Activation, Polyclonal Differentiation, and Isotype Expression (1985) (0)
S1783 Transferred CD4+ T Cells Induce Tight Junction Assembly Through Notch Signaling Pathway in the Distal Colon of RAG1-/- Deficient Mice (2010) (0)
S1676 The Presence of a Distinct Population of Lamina Propria TH17/FOXP3+ Cells in Crohn's Disease (2009) (0)
Preface (2004) (0)
A Traditional Chinese Herbal Formulation ‐ FAHF‐2 for the Treatment of Crohn's Disease: P‐116 (2012) (0)
T cells activated by intestinal epithelium (IEC) are IL7 dependent, oligoclonal and secrete Г interferon (2000) (0)
M2071 Innate Immune Defects in IRGM1, TLR2, and NOD2 Contribute to Crohn's Disease Risk and Severity in Ashkenazi Jews (2008) (0)
The formation of a novel class Ib:gp180 complex on the surface of intestinal epithelial cells triggers a signaling cascade resulting in the activation of CD8+ suppressor T cells (1998) (0)
IL-10 is necessary for the induction of low dose tolerance (2003) (0)
Induction of high and low dose oral tolerance in isolated small bowel loops with and without peyers patches (2003) (0)
Pancytopenia in a Patient Treated with 6MP and Fluconazole: A Novel Drug Interaction: 817 (2007) (0)
Transferred CD4+ T cells induce tight junction assembly through Notch signaling pathway in the distal colon of RAG1−/− deficient mice. (2011) (0)
Intestine derived endothelial cells (HIMECs) express CD40 which correlates with enhanced tissue factor expression (2000) (0)
T1799 Differing Immune Responses to Commensal Bacteria in IBD Patients Compared With Healthy Controls (2010) (0)
The Wiskott-Aldrich Syndrome protein alters Treg homeostasis via reduced strength of T cell receptor signaling. (2011) (0)
Inflammatory Bowel Diseases (2014) (0)
Local immune responses in tuberculosis (2005) (0)
IgE Sensitization to Milk and Peanut are Associated with Increased IL-4 but not GATA-3 Expression from Antigen-Stimulated Leukocytes in Atopic Infants (COFAR Observational Study of Food Allergy) (2010) (0)
Working out mechanisms of controlled/physiologic inflammation in the GI tract (2012) (0)
HLA-E is expressed by intestinal epithelial cells and is regulated by Г-interferon (2000) (0)
Reduced Peripheral T Lymphocyte and Lamina Propria Lymphocyte Cytokine Production in Patients with Inflammatory Bowel Disease (IBD) Associated with Common Variable Immunodeficiency (CVID) (2008) (0)
W1212 The Role of CD8+ T Cells in Oral Tolerance (2008) (0)
Tu1968 Increased Sensitivity to TGF Results in Defects in T Cell Proliferation and Regulatory T Cell Induction in the Absence of Wiskott-Aldrich Syndrome Protein (WASp) (2012) (0)
Efficacy of Infliximab in Ulcerative Colitis in a Clinical Practice Setting: 1179 (2006) (0)
P-203 The Role for TGF-&bgr; in Generation of IL-17+ regulatory T cells in Crohn’s Inflamed Gut Mucosa (2013) (0)
Su1858 Integrative Networks Identify Novel Regulators of Susceptibility and Pathogenesis of Inflammatory Bowel Disease (2016) (0)
The Role of CD8+ T cells in the Development of Oral Tolerance (2007) (0)
Mucosal Injury and Immunopathology: An Overview (2005) (0)
A subset of Cd8+regulatory T cells interacts with an intestinal epithelial cell complex formed by Cd1d and a CEA subfamily member (2003) (0)
Inflammatory bowel disease: autoimmunity or chronic inflammation? (2000) (0)
Decreased IL-2 production by PHA/PMA stimulated lamina propria lymphocytes in ulcerative colitis: Lack of in vitro downregulation by rIL-10 (1995) (0)
Intestinal Epithelial Cell MicroRNA-7 Modulates CD 98 Expression RNAs : RNA-Mediated Regulation and Noncoding (2009) (0)
850e CEACAM5 small peptides to restore the suppressive activity of lamina propria CD8+ T cells in Crohn's disease (2014) (0)
Class ih expression defect in IBD epithelial cells: Lack of coordinate regulation of CD1d and the epithelially expressed CD8 ligand, gp180 (2001) (0)
W1810 CD8+ CD28− Regulatory T Cells Mediating Contact Dependent Inhibition are Absent in the Lamina Propria but Present in the Peripheral Blood of Patients With Crohn's Disease (2010) (0)
Tu1938 Factors Mediating the Induction of Intestinal IL-17-Producing Tregs in Inflamed Gut Mucosa (2012) (0)
M2001 Toll-Like Receptor 4 (TLR4) Expression: A Biomarker for Inflammation-Associated Dysplasia of the Gastrointestinal Tract (2009) (0)
Soluble factors secreted by IBD tissue explants can induce B7-2 expression on intestinal crypt epithelial cells: Relevance with ulcerative colitis (1998) (0)
P-194 Use of CEACAM5 Synthetic Peptides to Induce Activation of CD8+ Suppressor Regulatory T Cells (2013) (0)
Composition of Cellular Infiltrates in the Intestine of Patients with Common Variable Immunodeficiency (CVID) (2009) (0)
Author: Sudeepta Aggarwal Ph.D. Associate Director, BDR, Immune Tolerance Network (2012) (0)
Gastrointestinal Priming and Recruitment of Th2 Lymphocytes in Food Allergy (2007) (0)
Progranulin Plays a Protective Role in the Pathogenesis of Inflammatory Bowel Disease. (2012) (0)
Tu1115 Epithelial CEACAM5 Expression At the Non-Inflamed Proximal Resection Margin of CD Patients Undergoing Ileo-Colic Resection Correlates With Post-Operative Histological Disease Recurrence At 6 Months (2013) (0)
Microbial Antigen Sensitization and Colitis in Chronic Granulomatous Disease and Hyper IgE Syndrome (2010) (0)
Regulation of IgA synthesis and secretion: role of isotype restricted and nonrestricted signals. (1988) (0)
The Wiskott Aldrich Syndrome protein (WASp) reduces T cell proliferation and regulatory T cell induction via increased sensitivity to TGFβ: P-210. (2011) (0)
Tu1837 The Notch Signaling Pathway Mediates Tight Junction Protein Stiochiometry in IBD (2012) (0)
associated diseases. Also, for patients with CD, treating physicians might need to consider "TNF implications" of all a patient's medicines. (2001) (0)
Sialic acid residues on the epithelial cell membrane glycoprotein, gp180, play a role in the interactions between intestinal epithelial cells and T cells (1998) (0)
Editor's Note: Listeria monocytogenes Promotes Tumor Growth via Tumor Cell Toll-Like Receptor 2 Signaling. (2019) (0)
CEACAM5 is Upregulated With Inflammation in Crohn's Colitis in Response to IL-22 (2011) (0)
Introduction to the special issue on Immunology at Mount Sinai (2012) (0)
The Notch-1 signaling pathway is required for a functional colonic barrier in WT mice: P-206. (2011) (0)
Mucosal Immunology of the Intestine (2010) (0)
The Role of CD8+ T cells in the Development of Oral Tolerance (B14) (2007) (0)
The Mucosal Immune System (2014) (0)
M1691 IFN-γ and Lamina Propria Lymphocytes (LPLS) Regulate Sox9 and Gp180 Expression in Fresh Intestinal Epithelial Cells (IECs) (2008) (0)
P-204 Anti-inflammatory Effects of the Chinese Herbal Formula FAHF-2 in Experimental and Human IBD (2013) (0)
Adverse Reactions to Food Antigens : Basic Science (2007) (0)
The Notch-1 Signaling Pathway is Required for Functional Colonic Barrier in wt Mice (2011) (0)
Intestinal epithelial cells (IECs) from IBD patients preferentially stimulate IFN-γ production by CD4+ T cells (2001) (0)
WASp Alters Regulatory T Cell Induction via Reduced Strength of T Cell Receptor Signaling (2011) (0)
Potential Role of Interleukin-4 Secreting Non-T Cells in the Development of Food Allergy (2011) (0)
1 The Mucosal Immune System (2014) (0)
Evidence Against a Defect in Immune Host Defenses as a Primary Process in IBD (1990) (0)
with Hepatocyte Secretion of IL-10 Enhanced Oral Tolerance in Transgenic Mice (2013) (0)
Mucosal immunity. (2003) (0)
Epstein-Barr virus-induced gene 3 is a negative regulator of IL-17 and protective immunity against Listeria monocytogenes (2007) (0)
TGF‐&bgr; as a Key Factor for Generation of IL‐17‐Producing Regulatory T Cells in Inflamed Gut Mucosa: P‐170 YI (2012) (0)
Relationship of Cytokine and Regulatory Gene Expression to the Outcomes of Milk and Egg Allergy in an Atopic Cohort (COFAR2) (2012) (0)
Epstein-Barr virus-induced gene 3 is a negative regulator of IL-17 and protective immunity against Listeria monocytogenes (95.4) (2007) (0)
Defective gp180 expression in the buccal mucosa of patients with ulcerative colitis but not with Crohn's disease (1998) (0)
S1616 IL-13 Plays a Critical Role in Development of Enterochromaffin Cell Hyperplasia and Production of Serotonin (2009) (0)
M1781 The Ability to Induce an Allergic Response is Related to the Intrinsic Properties of Cow's Milk Antigens (2010) (0)
138 Use of CEACAM5 Synthetic Peptide Combinatorial Library to Characterize Binding of CEACAM5 to CD8α (2013) (0)
The effectiveness and mechanism of a traditional Chinese herbal formulation for Crohnʼs disease: P-216. (2011) (0)
Toll-like Receptor Polymorphisms in Infants With Likely Milk/Egg Allergy: Consortium for Food Allergy Research (CoFAR) (2010) (0)
The Skin Is A Potent Site Of Allergic Sensitization To Multiple Food Allergens (2012) (0)
M1668 Defective CD8+ CD28- Regulatory T Cells in the Intestine of Patients with Crohn's Disease (2009) (0)
physiologic routes in an adjuvant-dependent manner (2011) (0)
Gp180, a CD8 ligand expressed by intestinal epithelial cells, inhibits the activation of class i restricted cytotoxic T cells (2000) (0)
Cutaneous Allergen Sensitization Primes for Anaphylaxis in an Adjuvant Dependent Manner (2011) (0)
Orthotopic tracheal transplantation in the murine model1 (2002) (0)
Chapter 63 – Immunodeficiency and Mucosal Immunity: An Overview (2005) (0)
ZINC BUT NOT rIL-10 DOWNREGULATES IL-2 PRODUCTION BY LAMINA PROPRIA LYMPHOCYTES IN CROHNʼS DISEASE (1995) (0)
The Notch signaling pathway mediates tight junction protein stiochiometry in IBDP-203. (2011) (0)
A Rare Case of Thymoma Associated Autoimmune Enteropathy: 686 (2008) (0)
Keratinocyte growth factors 1 (KGF-1) and 2 (KGF-2) induce expression of claudins 1–4 in human colon cancer cell lines (2003) (0)
HCV quasipecies complexity is related to CD4 cell count and HCV genotype in HIV coinfected patients (2001) (0)
A long needed re-evaluation of cells that suppress. (2008) (0)
Mucosal immunology of tolerance and allergy in the gastrointestinal tract (2012) (0)
Immunobiology of Epithelial Cells in Inflammatory Bowel Disease (2012) (0)
Tu1839 Mapping Binding of CEACAM5 to CD8a (2012) (0)
Essential Clinical Immunology: Immunological Aspects of Gastrointestinal and Liver Disease (2009) (0)
Visilizumab Promotes Expansion of Lamina Propria CD8+ Regulatory T Cells Through Non-Conventional T Cell Receptor Signaling Cascades (2011) (0)
P108 Visilizumab Therapy in Subjects With Moderate-To-Severe, Refractory Crohn's Disease (2007) (0)
Antigen Up‐take by Intestinal Epithelial Cells in IBD: P‐224 (2012) (0)
Circulating levels of tumor necrosis factor are elevated in end-stage congestive heart failure: A possible cause of cardiac cachexia (1990) (0)
Therapeutic advances and issues of patient adherence in the treatment of ulcerative colitis (2007) (0)
Generation of T Cell Hybridomas (1991) (0)
Zinc downregulates IL-2 production by lamina propria lymphocytes in Crohn's disease (1995) (0)
S1784 A 3D-Visualization of Epithelial Barrier Function Shows a Different Pattern of Tight Junction Dysregulation in CD Versus UC (2010) (0)
T cell signaling via the toll-receptor associated activator of interferon (TRIF) pathway protects from the development of acute and chronic murine colitis: O-0015. (2008) (0)
CORRELATION OF IMMUNE RESPONSES WITH HIV PLASMA VIREMIA. † 1074 (1996) (0)
W1793 Identification of IL-17-Producing FOXP3+ Regulatory T Cells in Crohn's Disease (2010) (0)
R095: Long-Term Outcomes of Orthotopic Tracheal Allografts in the Murine Model (2003) (0)
Introduction to the special issue on Immunology at Mount Sinai (2012) (0)
W1611 The Effect of the Route of Sensitization in the Induction of a Cow's Milk Allergic Response (2009) (0)
Lack of activation of CD1d-restricted CD8+ regulatory T cells in inflammatory bowel disease (2003) (0)
Mo1796 Serologic Response Towards Glycans in Chronic Granulomatous Disease Patients Supports an Innate Immune Defect in Crohn's Disease Pathogenesis (2012) (0)
Tu1873 A Population of Cytokine Deficient CD4+ T Cells is Associated With Increased Body Mass Index and Intestinal Inflammation (2012) (0)
The expression of Co-stimulatory molecules B7h and B7-H1 on colonic epithelial cells and their functional role in T cell activation (2003) (0)
Human Intestinal Epithelial Cells of Proinflammatory Cytokine Binding on The Regulation and Functional Consequence (1998) (0)
Tumor necrosis factor-alpha induces airway mucus cell production and collagen deposition in vivo (2005) (0)
Clinical Factors And Laboratory Correlates Of Milk Allergy Resolution In A Cohort Of Infants With Milk Allergy (CoFAR) (2011) (0)
Mapping CEACAM5 and CD8α binding: O-34. (2011) (0)
W1604 Transferred CD4+ T Cells Induce IEC Differentiation and Decrease Permeability in the Distal Colon of Rag1-/- Deficient Mice (2009) (0)
M1689 Transferred Naive and Regulatory T Cells Are Mandatory for Normal IEC Differentiation in the Colon of RAG1-/- Deficient Mice (2008) (0)

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