Lon Cardon
American geneticist
Lon Cardon's AcademicInfluence.com Rankings

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Biology
Lon Cardon's Degrees
- PhD Genetics Stanford University
Why Is Lon Cardon Influential?
(Suggest an Edit or Addition)According to Wikipedia, Lon Ray Cardon is an American human geneticist who is President and Chief Executive Officer of The Jackson Laboratory. Previous to joining The Jackson Laboratory in 2021, he had roles as Chief Scientific Officer and Chief Scientific Strategy Officer at BioMarin Pharmaceutical and senior vice president at GlaxoSmithKline, where he worked to translate the results of genetic research regarding the causes of human diseases into improved medical treatments. Prior to his work in the pharmaceutical industry, he conducted academic research on the genetic basis of human diseases, serving as full professor at the University of Oxford in the United Kingdom from 1998 to 2006, and at the University of Washington and Fred Hutchinson Cancer Research Center in the United States from 2006 to 2008.
Lon Cardon's Published Works
Published Works
- Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls (2007) (9208)
- Finding the missing heritability of complex diseases (2009) (7749)
- A second generation human haplotype map of over 3.1 million SNPs (2007) (4567)
- A Common Variant in the FTO Gene Is Associated with Body Mass Index and Predisposes to Childhood and Adult Obesity (2007) (4268)
- Merlin—rapid analysis of dense genetic maps using sparse gene flow trees (2002) (3486)
- Genome-wide association studies for complex traits: consensus, uncertainty and challenges (2008) (2939)
- Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease (2008) (2621)
- Replication of Genome-Wide Association Signals in UK Samples Reveals Risk Loci for Type 2 Diabetes (2007) (2245)
- Methodology for Genetic Studies of Twins and Families (1992) (1624)
- Association study designs for complex diseases (2001) (1520)
- Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants (2007) (1421)
- Replicating genotype–phenotype associations (2007) (1367)
- Population stratification and spurious allelic association (2003) (1242)
- Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility (2007) (1227)
- A general test of association for quantitative traits in nuclear families. (2000) (1183)
- Data quality control in genetic case-control association studies (2010) (1085)
- A large-scale genome-wide association study of Asian populations uncovers genetic factors influencing eight quantitative traits (2009) (976)
- Genome-wide strategies for detecting multiple loci that influence complex diseases (2005) (962)
- The support of human genetic evidence for approved drug indications (2015) (930)
- Thousands of chemical starting points for antimalarial lead identification (2010) (915)
- The effects of human population structure on large genetic association studies (2004) (886)
- Venezuelan kindreds reveal that genetic and environmental factors modulate Huntington's disease age of onset. (2004) (713)
- An Abundance of Rare Functional Variants in 202 Drug Target Genes Sequenced in 14,002 People (2012) (691)
- A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21 (2007) (686)
- An 18-kDa Translocator Protein (TSPO) polymorphism explains differences in binding affinity of the PET radioligand PBR28 (2011) (628)
- Quantitative Trait Loci (1995) (569)
- Quantitative trait locus for reading disability on chromosome 6. (1994) (557)
- Basic statistical analysis in genetic case-control studies (2011) (490)
- Genetic susceptibility to cancer: the role of polymorphisms in candidate genes. (2008) (479)
- Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease. (2005) (463)
- The complex interplay among factors that influence allelic association (2004) (460)
- Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease (2008) (455)
- Evaluating coverage of genome-wide association studies (2006) (431)
- A first-generation linkage disequilibrium map of human chromosome 22 (2002) (424)
- Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes. (2008) (424)
- Genetic Variants Influencing Circulating Lipid Levels and Risk of Coronary Artery Disease (2010) (417)
- GRR: graphical representation of relationship errors (2001) (416)
- A genomewide analysis provides evidence for novel linkages in inflammatory bowel disease in a large European cohort. (1999) (388)
- Using haplotype blocks to map human complex trait loci. (2003) (360)
- Extent and distribution of linkage disequilibrium in three genomic regions. (2001) (348)
- Genome-wide pharmacogenetic investigation of a hepatic adverse event without clinical signs of immunopathology suggests an underlying immune pathogenesis (2008) (342)
- Use of genome-wide association studies for drug repositioning (2012) (330)
- Positional cloning of a quantitative trait locus on chromosome 13q14 that influences immunoglobulin E levels and asthma (2003) (325)
- A genomewide scan for loci predisposing to type 2 diabetes in a U.K. population (the Diabetes UK Warren 2 Repository): analysis of 573 pedigrees provides independent replication of a susceptibility locus on chromosome 1q. (2001) (323)
- Pedigree tests of transmission disequilibrium (2000) (313)
- Why is CpG suppressed in the genomes of virtually all small eukaryotic viruses but not in those of large eukaryotic viruses? (1994) (309)
- Chromosome-wide distribution of haplotype blocks and the role of recombination hot spots (2003) (289)
- Independent genome-wide scans identify a chromosome 18 quantitative-trait locus influencing dyslexia (2002) (285)
- Inflammatory bowel disease is associated with a TNF polymorphism that affects an interaction between the OCT1 and NF(-kappa)B transcription factors. (2002) (282)
- Measures of human population structure show heterogeneity among genomic regions. (2005) (277)
- What makes a good case-control study? Design issues for complex traits such as endometriosis. (2002) (267)
- A genome-wide search for schizophrenia susceptibility genes. (1998) (260)
- HLA-DQA1*02:01 is a major risk factor for lapatinib-induced hepatotoxicity in women with advanced breast cancer. (2011) (256)
- A 77-kilobase region of chromosome 6p22.2 is associated with dyslexia in families from the United Kingdom and from the United States. (2004) (253)
- Shaking the tree: mapping complex disease genes with linkage disequilibrium (2005) (251)
- Pervasive CpG suppression in animal mitochondrial genomes. (1994) (249)
- A high-resolution linkage-disequilibrium map of the human major histocompatibility complex and first generation of tag single-nucleotide polymorphisms. (2005) (248)
- Two-Stage Two-Locus Models in Genome-Wide Association (2006) (244)
- Exome sequencing and characterization of 49,960 individuals in the UK Biobank (2020) (244)
- Clustering of hypertension, diabetes, and obesity in adult male twins: same genes or same environments? (1994) (228)
- The impact of SNP density on fine-scale patterns of linkage disequilibrium. (2004) (204)
- Linkage disequilibrium mapping via cladistic analysis of single-nucleotide polymorphism haplotypes. (2004) (203)
- Functional epistasis on a common MHC haplotype associated with multiple sclerosis (2006) (201)
- IL23R Variation Determines Susceptibility But Not Disease Phenotype in Inflammatory Bowel Disease (2007) (199)
- Indication for Linkage of the Human OB Gene Region With Extreme Obesity (1996) (197)
- Efficient selective screening of haplotype tag SNPs (2003) (196)
- Designing candidate gene and genome-wide case–control association studies (2007) (188)
- Genetic analysis of inflammatory bowel disease in a large European cohort supports linkage to chromosomes 12 and 16. (1998) (180)
- Investigation of the fine structure of European populations with applications to disease association studies (2008) (178)
- Additional support for schizophrenia linkage on chromosomes 6 and 8: a multicenter study. Schizophrenia Linkage Collaborative Group for Chromosomes 3, 6 and 8. (1996) (175)
- Guidelines for genotyping in genomewide linkage studies: single-nucleotide-polymorphism maps versus microsatellite maps. (2004) (164)
- Heavy consumption of cigarettes, alcohol and coffee in male twins. (1997) (161)
- Pazopanib efficacy in renal cell carcinoma: evidence for predictive genetic markers in angiogenesis-related and exposure-related genes. (2011) (159)
- The genetic basis of endometriosis (2001) (158)
- The complex interplay among factors that influence allelic association (2004) (153)
- Expectation maximization algorithm for identifying protein-binding sites with variable lengths from unaligned DNA fragments. (1992) (152)
- The consumption of tobacco, alcohol, and coffee in Caucasian male twins: a multivariate genetic analysis. (1996) (147)
- Quantitative trait locus for reading disability on chromosome 6p is pleiotropic for attention-deficit/hyperactivity disorder. (2002) (147)
- Linkage disequilibrium in young genetically isolated Dutch population (2004) (146)
- Loci for regulation of bone mineral density in men and women identified by genome wide linkage scan: the FAMOS study. (2005) (145)
- The impact of genotyping error on family-based analysis of quantitative traits (2001) (144)
- The interleukin 1 gene cluster contains a major susceptibility locus for ankylosing spondylitis. (2004) (139)
- Use of multivariate linkage analysis for dissection of a complex cognitive trait. (2003) (136)
- Risk prediction of prevalent diabetes in a Swiss population using a weighted genetic score—the CoLaus Study (2009) (126)
- Whole exome sequencing and characterization of coding variation in 49,960 individuals in the UK Biobank (2019) (126)
- Osteoarthritis-susceptibility locus on chromosome 11q, detected by linkage. (1999) (126)
- Quantitative trait locus for reading disability: correction. (1995) (123)
- Localization of the Netherton syndrome gene to chromosome 5q32, by linkage analysis and homozygosity mapping. (2000) (122)
- Genetic control of susceptibility to infection with Mycobacterium tuberculosis in mice (2000) (120)
- A comparison of linkage disequilibrium patterns and estimated population recombination rates across multiple populations. (2005) (120)
- Familiality of physical and metabolic characteristics that predict the development of non-insulin-dependent diabetes mellitus in Pima Indians. (1997) (119)
- Is disease severity in ankylosing spondylitis genetically determined? (2001) (118)
- Confirmation of the role of ATG16l1 as a Crohn's disease susceptibility gene (2007) (117)
- Multiple regression analysis of sib-pair data on reading to detect quantitative trait loci (1991) (117)
- Analysis of the IBD5 locus and potential gene-gene interactions in Crohn’s disease (2003) (116)
- Pazopanib-induced hyperbilirubinemia is associated with Gilbert's syndrome UGT1A1 polymorphism (2010) (115)
- A simple method for automated allele binning in microsatellite markers. (1997) (115)
- An evaluation of HapMap sample size and tagging SNP performance in large-scale empirical and simulated data sets (2005) (114)
- The Relationship Between CAG Repeat Length and Age of Onset Differs for Huntington's Disease Patients with Juvenile Onset or Adult Onset (2007) (113)
- Trans-ethnic fine mapping of a quantitative trait locus for circulating angiotensin I-converting enzyme (ACE). (2001) (108)
- Bivariate linkage scan for reading disability and attention-deficit/hyperactivity disorder localizes pleiotropic loci. (2005) (108)
- TUCAN (CARD8) genetic variants and inflammatory bowel disease. (2006) (104)
- Evaluating the effects of imputation on the power, coverage, and cost efficiency of genome-wide SNP platforms. (2008) (102)
- Site and Gender Specificity of Inheritance of Bone Mineral Density (2003) (101)
- The portability of tagSNPs across populations: a worldwide survey. (2006) (101)
- The power to detect linkage disequilibrium with quantitative traits in selected samples. (2001) (100)
- An Evaluation of the Performance of Tag SNPs Derived from HapMap in a Caucasian Population (2006) (100)
- Linkage of bipolar affective disorder to chromosome 18 markers in a new pedigree series. (1997) (100)
- Contribution of the novel inflammatory bowel disease gene IL23R to disease susceptibility and phenotype (2007) (100)
- Behavior Genetic Approaches in Behavioral Medicine (1995) (95)
- Familial aggregation of endometriosis in a large pedigree of rhesus macaques. (2004) (94)
- Identification of a new malaria susceptibility locus (Char4) in recombinant congenic strains of mice (2001) (90)
- Identification of major loci controlling clinical manifestations of ankylosing spondylitis. (2003) (90)
- Replication of twelve association studies for Huntington’s disease residual age of onset in large Venezuelan kindreds (2006) (90)
- The future of genetic epidemiology. (1998) (89)
- Finding the missing heritability of complex (2009) (87)
- Evaluating the results of genomewide linkage scans of complex traits by locus counting. (2002) (83)
- Lymphotoxin-α Gene and Risk of Myocardial Infarction in 6,928 Cases and 2,712 Controls in the ISIS Case-Control Study (2006) (83)
- Genetic control of blood parasitaemia in mouse malaria maps to chromosome 8 (1997) (82)
- The impact of genotyping error on haplotype reconstruction and frequency estimation (2002) (82)
- Susceptibility to tuberculosis: A locus on mouse chromosome 19 (Trl-4) regulates Mycobacterium tuberculosis replication in the lungs (2003) (79)
- Etiology of Reading Difficulties and Rapid Naming: The Colorado Twin Study of Reading Disability (2001) (77)
- Replication and extension studies of inflammatory bowel disease susceptibility regions confirm linkage to chromosome 6p (IBD3) (2001) (77)
- Computational DNA sequence analysis. (1994) (76)
- Testing drug response in the presence of genetic information: sampling issues for clinical trials. (2000) (68)
- The genetics of NOD-like receptors in Crohn's disease. (2010) (68)
- Efficiency and consistency of haplotype tagging of dense SNP maps in multiple samples. (2004) (68)
- Prospective validation of HLA-DRB1*07:01 allele carriage as a predictive risk factor for lapatinib-induced liver injury. (2014) (66)
- The IBD6 Crohn's disease locus demonstrates complex interactions with CARD15 and IBD5 disease-associated variants. (2003) (65)
- Genomewide linkage scan reveals novel loci modifying age of onset of Huntington's disease in the Venezuelan HD kindreds (2008) (63)
- Genetic etiology of comorbid reading difficulties and ADHD. (2003) (63)
- Evidence for a Major Gene for Bone Mineral Density in Idiopathic Osteoporotic Families (2000) (62)
- Significant evidence of one or more susceptibility loci for endometriosis with near-Mendelian inheritance on chromosome 7p13-15. (2007) (61)
- Fine mapping versus replication in whole-genome association studies. (2007) (58)
- Allelic association patterns for a dense SNP map (2004) (56)
- Carriage of the V279F Null Allele within the Gene Encoding Lp-PLA2 Is Protective from Coronary Artery Disease in South Korean Males (2011) (56)
- Evidence for linkage of stature to chromosome 3p26 in a large U.K. Family data set ascertained for type 2 diabetes. (2002) (55)
- Prospects and pitfalls in whole genome association studies (2005) (52)
- Single nucleotide polymorphisms in TNFSF 15 confer susceptibility to Crohn ’ s disease (2005) (52)
- Precision medicine, genomics and drug discovery. (2016) (51)
- Genetic and environmental correlations between obesity and body fat distribution in adult male twins. (1994) (51)
- Marker selection for genetic case–control association studies (2009) (51)
- Association of the hemochromatosis gene with pazopanib-induced transaminase elevation in renal cell carcinoma. (2011) (50)
- A candidate gene study of F cell levels in sibling pairs using a joint linkage and association analysis. (1999) (49)
- Continuity and Change in General Cognitive Ability from 1 to 7 years of Age. (1992) (48)
- Fine mapping of the MHC Class III region demonstrates association of AIF1 and rheumatoid arthritis. (2008) (47)
- Multivariate genetic analysis of specific cognitive abilities in the Colorado adoption project at age 7 (1992) (45)
- Investigation of Quantitative Measures Related to Reading Disability in a Large Sample of Sib-Pairs from the UK (2001) (44)
- Differential Genetic Etiology of Reading Component Processes as a Function of IQ (2002) (44)
- Some Properties of a Variance Components Model for Fine-Mapping Quantitative Trait Loci (2000) (44)
- The Use of Genome-Wide eQTL Associations in Lymphoblastoid Cell Lines to Identify Novel Genetic Pathways Involved in Complex Traits (2011) (44)
- Continuity and change in cognitive development. (1993) (43)
- Singleton SNPs in the human genome and implications for genome-wide association studies (2008) (43)
- Association Analysis in a Variance Components Framework (2001) (43)
- Assessments of DNA inhomogeneities in yeast chromosome III. (1993) (42)
- Delivering New Disease Genes (2006) (42)
- Aspects of observing and claiming allele flips in association studies (2009) (40)
- Deep Resequencing Unveils Genetic Architecture of ADIPOQ and Identifies a Novel Low-Frequency Variant Strongly Associated With Adiponectin Variation (2012) (40)
- A population-based study of personality in 34 000 sib-pairs (2000) (39)
- Evidence from a large U.K. family collection that genes influencing age of onset of type 2 diabetes map to chromosome 12p and to the MODY3/NIDDM2 locus on 12q24. (2004) (39)
- Genome-wide association: a promising start to a long race. (2006) (38)
- A genetic and environmental time series analysis of blood pressure in male twins (1993) (37)
- Linkage analyses of schizophrenia to chromosome 6p24-p22: an attempt to replicate. (1996) (36)
- A comparison of tagging methods and their tagging space. (2005) (36)
- Genetic Influences on Body Mass Index in Early Childhood (1995) (36)
- Fine mapping of the IBD1 locus did not identify Crohn disease-associated NOD2 variants: implications for complex disease genetics. (2002) (36)
- Characterization of ADME gene variation in 21 populations by exome sequencing (2016) (35)
- Multivariate Genetic Analysis of Chronic Pelvic Pain and Associated Phenotypes (2005) (35)
- Genetic correlations between reading performance and IQ in the Colorado Adoption Project (1990) (35)
- Genetically indistinguishable SNPs and their influence on inferring the location of disease-associated variants. (2005) (33)
- Quantitative-Trait Locus for Specific Language and Reading Deficits on Chromosome 6 p (1999) (33)
- Whole Genome Association (2008) (31)
- Novelty in the target landscape of the pharmaceutical industry (2013) (31)
- Identification of a Variant in KDR Associated with Serum VEGFR2 and Pharmacodynamics of Pazopanib (2014) (30)
- Genotype prediction using a dense map of SNPs (2004) (30)
- GLIDERS - A web-based search engine for genome-wide linkage disequilibrium between HapMap SNPs (2009) (29)
- Sequencing of Lp-PLA2-encoding PLA2G7 gene in 2000 Europeans reveals several rare loss-of-function mutations (2011) (29)
- Replicating genotype – phenotype associations What constitutes replication of a genotype – phenotype association , and how best can it be achieved ? (2007) (29)
- A phenome-wide association study of a lipoprotein-associated phospholipase A2 loss-of-function variant in 90 000 Chinese adults (2016) (29)
- Deep sequencing of the LRRK2 gene in 14,002 individuals reveals evidence of purifying selection and independent origin of the p.Arg1628Pro mutation in Europe (2012) (27)
- Sequenced in 14 , 002 People An Abundance of Rare Functional Variants in 202 Drug Target Genes (2013) (27)
- Replication Publication (2005) (25)
- A model of developmental change in hierarchical phenotypes with application to specific cognitive abilities (1994) (25)
- Lipoprotein-Associated Phospholipase A2 Loss-of-Function Variant and Risk of Vascular Diseases in 90,000 Chinese Adults (2016) (24)
- The Effect of Genotype and Pedigree Error on Linkage Analysis: Analysis of Three Asthma Genome Scans (2001) (24)
- Development of a Web site for the genetic epidemiology of endometriosis. (2002) (23)
- The Genetic Epidemiology of Spontaneous Endometriosis in the Rhesus Monkey (2002) (23)
- To what extent do scans of non-synonymous SNPs complement denser genome-wide association studies? (2008) (23)
- A Sib-Pair Regression Model of Linkage Disequilibrium for Quantitative Traits (2000) (21)
- Discussion on the meeting on ‘Statistical modelling and analysis of genetic data’ (2002) (21)
- The application of genetics to the discovery of better medicines. (2002) (19)
- Analysis of the IBD 5 locus and potential gene-gene interactions in Crohn ’ s disease (2003) (18)
- Specific cognitive abilities. (1994) (18)
- Interleukin-18 as a drug repositioning opportunity for inflammatory bowel disease: A Mendelian randomization study (2019) (18)
- Sources of Continuity in Infant Predictors of Later IQ. (1991) (17)
- Comparative DNA sequence features in two long Escherichia coli contigs. (1993) (17)
- Trial watch: Impact of genetically supported target selection on R&D productivity (2016) (17)
- A LISREL 8 model with constrained parameters for twin and adoptive families (1991) (16)
- Direction of Causation (1992) (16)
- Optimizing the Power of Genome-Wide Association Studies by Using Publicly Available Reference Samples to Expand the Control Group (2010) (16)
- Inflammatory bowel disease is associated with a functional TNF polymorphism that affects an OCT1/NF-KB transcription factor interaction (2002) (15)
- Fine-Scale Map of Encyclopedia of DNA Elements Regions in the Korean Population (2006) (15)
- Waiting for the working draft from the human genome project (2000) (15)
- How useful is the fine‐scale mapping of complex trait linkage peaks? Evaluating the impact of additional microsatellite genotyping on the posterior probability of linkage (2005) (15)
- GOLDsurfer: three dimensional display of linkage disequilibrium (2004) (15)
- Drawing Moral Inferences from Descriptive Science (1989) (15)
- Genetics of specific cognitive abilities. (1993) (14)
- The exon 1–8C/G SNP in the PSMA6 gene contributes only a small amount to the burden of myocardial infarction in 6946 cases and 2720 controls from a United Kingdom population (2008) (14)
- Genetic mediation in the relationship of education to cognitive function in older people. (1995) (14)
- Factorial validation of a telephone test battery of specific cognitive abilities (1992) (13)
- The Scope of Genetic Analyses (1992) (13)
- Goldsurfer2 (Gs2): A comprehensive tool for the analysis and visualization of genome wide association studies (2008) (13)
- A Note on the Power to Detect Transmission Distortion in Parent-Child Trios via the Transmission Disequilibrium Test (2006) (13)
- Will the real disease gene please stand up? (2005) (11)
- Linkage disequilibrium mapping via cladistic analysis of SNP haplotypes. (2003) (11)
- Introduction to the Special Issue on Variance Components Methods for Mapping Quantitative Trait Loci (2004) (8)
- Il-23r is a major determinant of ankylosing spondylitis risk - The tasc study (2007) (8)
- Disentangling Linkage Disequilibrium and Linkage From Dense Single-Nucleotide Polymorphism Trio Data (2005) (8)
- Impact of genetically supported target selection on R&D productivity. (2016) (8)
- Transmission disequilibrium testing confirms the association of the TNFα 1031C allele with Crohn's disease (2001) (7)
- Practical barriers to identifying complex trait loci. (2003) (7)
- Association of germ-line genetic markers in IL8, HIF1A, VEGFA, and VEGFR2 with treatment response to pazopanib in renal cell carcinoma. (2010) (6)
- Hyperbilirubinemia in Lapatinib Treated Patients Is Associated with Gilbert's SyndromeUGT1A1Polymorphism. (2009) (6)
- A linkage disequilibrium map of chromosome 22 (2002) (6)
- Genomic control to the extreme - Reply (2004) (6)
- Genome-wide association analysis and replication of coronary artery disease in South Korea suggests a causal variant common to diverse populations (2010) (5)
- A re-examination of proximodistal patterning during vertebrate limb development (5)
- Index and Predisposes to Childhood and Adult Obesity Gene Is Associated with Body Mass FTO A Common Variant in the (2012) (5)
- Reply to "Genomic Control to the extreme" (2004) (5)
- Reply to Rational drug repositioning by medical genetics (2013) (4)
- Exome sequencing and characterization of 49,960 individuals in the UK Biobank (2020) (4)
- Sex-limitation and G × E Interaction (1992) (4)
- Linkage analysis of a common oligogenic disease using selected sib pairs (1995) (4)
- Association of the hemochromatosis (HFE) gene with pazopanib-induced transaminase elevations in renal cell carcinoma. (2010) (4)
- Mapping quantitative effects of oligogenes by allelic association (2002) (4)
- Path Analysis and Structural Equations (1992) (3)
- 2 Homozygosity mapping of Alström syndrome to chromosome (1997) (3)
- Towards defining the genetic determinants of disease severity in ankylosing spondylitis. (2001) (3)
- Genome‐Wide Association Studies (2019) (3)
- Type 2 Diabetes and Triglyceride Levels Genome-Wide Association Analysis Identifies Loci (3)
- LOCI FOR REGULATION OF BMD IN MEN AND WOMEN THE FAMOS STUDY (2004) (3)
- Genome-Wide Association Studies Herald a New Era of Rapid Discoveries in Inflammatory Bowel Disease Research (2007) (3)
- Model Fitting Functions and Optimization (1992) (2)
- Identifying therapeutic drug targets using bidirectional effect genes (2021) (2)
- Relationship of HLA-DQA1*0201 and lapatinib-induced hepatotoxicity in women with advanced breast cancer. (2010) (2)
- Identifying therapeutic drug targets for rare and common forms of short stature (2020) (2)
- Mapping quantitative effects of oligogenes by allelic association. (2002) (2)
- Power and Sample Size (1992) (2)
- CLINICAL-ALIMENTARY TRACT IL23R Variation Determines Susceptibility But Not Disease Phenotype in Inflammatory Bowel Disease (2007) (2)
- Linkage analyses of schizophrenia to chromosome 6p24-p22 (1996) (2)
- among genomic regions Measures of human population structure show heterogeneity (2005) (2)
- Pharmacogenetic investigation of lapatinib-associated diarrhea in metastatic breast cancer clinical trials. (2011) (1)
- 1114 Pazopanib-induced hyperbilirubinemia is associated with Gilbert's syndrome UGT1A1 polymorphism (2009) (1)
- Optimising the power of genome-wide association studies by using publicly available reference samples to expand the controls group (2009) (1)
- Determinants of success in genetic association studies of complex traits. (2003) (1)
- HLA-DRB1*07:01-DQA1*02:01 and UGT1A1*28 allele carriage in hepatic serious adverse event cases identified during lapatinib clinical trials. (2011) (1)
- High-density association mapping and comprehensive tagging of the type 2 diabetes linkage region on chromosome 1q in 4 European populations (2007) (1)
- The genetic epidemiology of endometriosis—development of a website for the aggregation of global evidence (2002) (1)
- How useful is fine mapping complex trait linkage scan peaks (2003) (1)
- Designing studies into the genetic epidemiology of endometriosis. (2002) (1)
- Mapping complex disease genes using linkage disequilibrium and genome-wide association scans (2011) (1)
- Genomewide linkage analysis of age of onset of Huntington's disease (2007) (1)
- The use of genome-wide eQTL associations to identify novel genetic pathways involved in complex traits (2008) (1)
- LISREL Models and Methods (1992) (1)
- Inflammatory bowel disease is associated with functional TNF polymorphism affecting OCT1/NF-kappa B interaction (2002) (1)
- Assessing population structure and its effects on association studies in a genome wide SNP dataset. (2002) (1)
- Assortment and Cultural Transmission (1992) (0)
- Combined Linkage and Association Analysis in Gene Discovery (2001) (0)
- Lessons from segregation analysis for the ascertainment of families for mapping of osteoporosis genes. (2002) (0)
- Multipoint methods for linkage analysis of quantitative trait loci in sib pairs (1994) (0)
- Replication strategies for whole genome association (WGA) studies (2007) (0)
- Venezuelan kindreds Huntington's disease residual age of onset in large Replication of twelve association studies for (2007) (0)
- Large-scale association studies to identify diabetes-susceptibility loci on chromosome 1q: The importance of stringent quality control (2006) (0)
- Interleukin-18 as a drug repositioning opportunity for inflammatory bowel disease: A Mendelian randomization study (2019) (0)
- Faculty Opinions recommendation of Genomewide scans of complex human diseases: true linkage is hard to find. (2001) (0)
- A first generation haplotype map of chromosome 19 (2002) (0)
- Genetic analysis of inflammatory bowel disease in a large european patient population supports linkage to human chromosomes 12 and 16 (1998) (0)
- Linkage disequilibrium mapping of the type 2 diabetes susceptibility variants on chromosome Iq in European populations (2005) (0)
- P191 The Genetics of NOD-Like Receptors Proteins in Crohn's Disease (2008) (0)
- Quantitative Trait Locus for Reading Disability on Chromosome 6 1 IIiiiiil (2005) (0)
- First evidence that one or more rare genetic polymorphisms with high penetrance may be involved in the aetiology of endometriosis (2005) (0)
- Site and gender specificity of the genetic control of bone density. (2000) (0)
- GOLDsurfer2: A comprehensive tool for the analysis and visualization of whole genome association studies (2007) (0)
- Bricker , and Humans Drosophila Yeast , A Mitochondrial Pyruvate Carrier Required for Pyruvate Uptake in (2012) (0)
- Replicated association between type 2 diabetes and variants in CAPON revealed by high density linkage disequilibrium mapping on chromosome 1q (2006) (0)
- Diabetes and Triglyceride Levels Genome-Wide Association Analysis Identifies Loci for Type 2 (2011) (0)
- Variation in the retinoid X receptor gamma gene is associated with type 2 diabetes in sample sets displaying linkage to chromosome 1q (2006) (0)
- Population-based survey of the EPQ in southern England (2000) (0)
- All in the family: Site and gender specificity of the genetic control of bone mineral density (2002) (0)
- Reply to letter from T Becker and M Knapp (2003) (0)
- as a drug repositioning opportunity for infammatory bowel disease: A Mendelian randomization study. (2019) (0)
- A case-control investigation using tag SNPs with Crohn's disease that span across the MHC class III (2007) (0)
- Regression models for association studies of quantitative trait loci in humans (2000) (0)
- Disentangling Linkage Disequilibrium and Linkage from Dense SNP Trio Data (2005) (0)
- Case History in Humans: Mapping QTLs for Complex Traits in Humans (1997) (0)
- Positional candidate gene selection on chromosome 1q using bioinformatics and large scale association analysis (2005) (0)
- Quantifying the effects of imputation on the power, coverage and cost-efficiency of genomewide SNP platforms (2008) (0)
- Linkage studies of the Type 2 diabetes susceptibility locus on chromosome 1q: Combined analysis of 1200 UK and French affected sibpairs (2002) (0)
- A population-based study of personal i ty in 34 000 sib-pai rs (2007) (0)
- Using combined datasets to find true associations in genome wide association studies (2007) (0)
- Faculty Opinions recommendation of Robustness of inference of haplotype block structure. (2003) (0)
- The effect of sample size on tagging SNP performance and consequences for complex disease gene mapping (2005) (0)
- The IL1 gene cluster is a major locus determining susceptibility to Ankylosing spondylitis. (2003) (0)
- Linkage disequilibrium mapping of the chromosome 12 (IBD2) inflammatory bowel disease susceptibility locus in an enlarged cohort (2003) (0)
- Fine Scale Map of ENCODE Regions in The Korean Population (2006) (0)
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