Lorena S. Beese
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American biochemist
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Lorena S. Beesebiology Degrees
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Biochemistry
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Biology
Lorena S. Beese's Degrees
- PhD Materials Science and Engineering Northwestern University
Why Is Lorena S. Beese Influential?
(Suggest an Edit or Addition)According to Wikipedia, Lorena Beese is a James B. Duke Professor of Biochemistry and Duke Cancer Institute Member. Her research involves structural mechanisms underlying DNA replication and repair, neurodegenerative diseases, cancer, and microbial pathogenesis; X-ray crystallography and cryo-electron microscopy; structure-based drug design; protein-protein and protein-nucleic acid interactions, enzyme mechanisms, chemical biology, protein structure and function.
Lorena S. Beese's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Structural basis for the 3′‐5′ exonuclease activity of Escherichia coli DNA polymerase I: a two metal ion mechanism. (1991) (883)
- Visualizing DNA replication in a catalytically active Bacillus DNA polymerase crystal (1998) (482)
- Crystal Structure of Protein Farnesyltransferase at 2.25 Angstrom Resolution (1997) (301)
- Structure of the Human MutSα DNA Lesion Recognition Complex (2007) (300)
- Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase (2004) (289)
- Genetic and crystallographic studies of the 3',5'-exonucleolytic site of DNA polymerase I. (1988) (274)
- Cocrystal structure of an editing complex of Klenow fragment with DNA. (1988) (273)
- Thematic review series: Lipid Posttranslational Modifications. Structural biology of protein farnesyltransferase and geranylgeranyltransferase type I Published, JLR Papers in Press, February 13, 2006. (2006) (269)
- Processive DNA synthesis observed in a polymerase crystal suggests a mechanism for the prevention of frameshift mutations (2003) (268)
- Structures of Mismatch Replication Errors Observed in a DNA Polymerase (2004) (265)
- Crystallographic analysis of CaaX prenyltransferases complexed with substrates defines rules of protein substrate selectivity. (2004) (245)
- Structural evidence for the rare tautomer hypothesis of spontaneous mutagenesis (2011) (220)
- Reaction path of protein farnesyltransferase at atomic resolution (2002) (169)
- Structure of the human MutSalpha DNA lesion recognition complex. (2007) (166)
- Crystal structure of farnesyl protein transferase complexed with a CaaX peptide and farnesyl diphosphate analogue. (1998) (166)
- Crystal structures of the Klenow fragment of DNA polymerase I complexed with deoxynucleoside triphosphate and pyrophosphate. (1993) (158)
- Electron microscopy of thin filaments decorated with a Ca2+-regulated myosin. (1980) (151)
- Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family (2011) (146)
- Crystal structure of a thermostable Bacillus DNA polymerase I large fragment at 2.1 A resolution. (1997) (144)
- Cocrystal structure of protein farnesyltransferase complexed with a farnesyl diphosphate substrate. (1998) (143)
- Crystal structure of a pol alpha family DNA polymerase from the hyperthermophilic archaeon Thermococcus sp. 9 degrees N-7. (2000) (140)
- The structural basis for the mutagenicity of O6-methyl-guanine lesions (2006) (130)
- Structure of mammalian protein geranylgeranyltransferase type‐I (2003) (119)
- The basis for K-Ras4B binding specificity to protein farnesyltransferase revealed by 2 A resolution ternary complex structures. (2000) (103)
- The crystal structure of human protein farnesyltransferase reveals the basis for inhibition by CaaX tetrapeptides and their mimetics (2001) (100)
- The Structure of a High Fidelity DNA Polymerase Bound to a Mismatched Nucleotide Reveals an “Ajar” Intermediate Conformation in the Nucleotide Selection Mechanism* (2011) (96)
- Visualization of Synaptic Inhibition with an Optogenetic Sensor Developed by Cell-Free Protein Engineering Automation (2013) (81)
- Structure of a High Fidelity DNA Polymerase Bound to a Benzo[a]pyrene Adduct That Blocks Replication* (2005) (78)
- Crystal structures of the anticancer clinical candidates R115777 (Tipifarnib) and BMS-214662 complexed with protein farnesyltransferase suggest a mechanism of FTI selectivity. (2004) (76)
- 3-Aminopyrrolidinone farnesyltransferase inhibitors: design of macrocyclic compounds with improved pharmacokinetics and excellent cell potency. (2002) (74)
- Observing Translesion Synthesis of an Aromatic Amine DNA Adduct by a High-fidelity DNA Polymerase* (2004) (70)
- Microtubule structure at 18 A resolution. (1987) (69)
- The mechanism of the translocation step in DNA replication by DNA polymerase I: a computer simulation analysis. (2010) (64)
- Structural Factors That Determine Selectivity of a High Fidelity DNA Polymerase for Deoxy-, Dideoxy-, and Ribonucleotides* (2012) (55)
- Dual protein farnesyltransferase-geranylgeranyltransferase-I inhibitors as potential cancer chemotherapeutic agents. (2003) (53)
- Crystallographic analysis reveals that anticancer clinical candidate L-778,123 inhibits protein farnesyltransferase and geranylgeranyltransferase-I by different binding modes. (2004) (50)
- MutLα and Proliferating Cell Nuclear Antigen Share Binding Sites on MutSβ* (2010) (46)
- Structure‐based design of robust glucose biosensors using a Thermotoga maritima periplasmic glucose‐binding protein (2007) (45)
- Structures of Cryptococcus neoformans Protein Farnesyltransferase Reveal Strategies for Developing Inhibitors That Target Fungal Pathogens* (2011) (45)
- Structure-based design and synthesis of potent, ethylenediamine-based, mammalian farnesyltransferase inhibitors as anticancer agents. (2010) (40)
- The crystal structure of a thermophilic glucose binding protein reveals adaptations that interconvert mono and di-saccharide binding sites. (2006) (40)
- Covalent protein-oligonucleotide conjugates by copper-free click reaction. (2012) (39)
- Sensing and Processing of DNA Interstrand Crosslinks by the Mismatch Repair Pathway. (2017) (38)
- Kinetic analysis of zinc ligand mutants of mammalian protein farnesyltransferase. (1998) (36)
- The MutSα-Proliferating Cell Nuclear Antigen Interaction in Human DNA Mismatch Repair*♦ (2008) (36)
- Interplay of catalysis, fidelity, threading, and processivity in the exo- and endonucleolytic reactions of human exonuclease I (2017) (36)
- Structural basis for binding and selectivity of antimalarial and anticancer ethylenediamine inhibitors to protein farnesyltransferase. (2009) (35)
- Conversion of protein farnesyltransferase to a geranylgeranyltransferase. (2006) (34)
- Ligand-induced conformational changes in a thermophilic ribose-binding protein (2008) (30)
- Resistance mutations at the lipid substrate binding site of Plasmodium falciparum protein farnesyltransferase. (2007) (29)
- Structural studies of Klenow fragment: an enzyme with two active sites. (1987) (29)
- Structural Analysis of a Periplasmic Binding Protein in the Tripartite ATP-independent Transporter Family Reveals a Tetrameric Assembly That May Have a Role in Ligand Transport* (2008) (28)
- The Closing Mechanism of DNA Polymerase I at Atomic Resolution. (2015) (27)
- Two DNA polymerases: HIV reverse transcriptase and the Klenow fragment of Escherichia coli DNA polymerase I. (1993) (27)
- Structural adaptations that modulate monosaccharide, disaccharide, and trisaccharide specificities in periplasmic maltose-binding proteins. (2009) (26)
- Rapid Analysis of Protein Farnesyltransferase Substrate Specificity Using Peptide Libraries and Isoprenoid Diphosphate Analogues (2014) (26)
- Structural Analysis of Semi-specific Oligosaccharide Recognition by a Cellulose-binding Protein of Thermotoga maritima Reveals Adaptations for Functional Diversification of the Oligopeptide Periplasmic Binding Protein Fold* (2009) (22)
- Protein farnesyltransferase. (1997) (19)
- Contact x-ray microscopy. A new technique for imaging cellular fine structure. (1986) (19)
- Structure of Protein Geranylgeranyltransferase-I from the Human Pathogen Candida albicans Complexed with a Lipid Substrate* (2008) (18)
- Discrimination between right and wrong purine dNTPs by DNA polymerase I from Bacillus stearothermophilus. (2009) (18)
- Crystal structures of the fungal pathogen Aspergillus fumigatus protein farnesyltransferase complexed with substrates and inhibitors reveal features for antifungal drug design (2014) (18)
- Following an environmental carcinogen N2-dG adduct through replication: elucidating blockage and bypass in a high-fidelity DNA polymerase (2007) (13)
- Dissecting the differences between the alpha and beta anomers of the oxidative DNA lesion FaPydG. (2008) (13)
- Conversion of Tyr361 beta to Leu in mammalian protein farnesyltransferase impairs product release but not substrate recognition. (2000) (11)
- Structure of microtubules with reduced hydration. Comparison of results from X-ray diffraction and electron microscopy. (1987) (11)
- Structural Biochemistry (2020) (8)
- Structure of E. Coli DNA Polymerase I, Large Fragment, and Its Functional Implications (1989) (7)
- Structural basis for the 3′ – 5′ exonuclease activity of Escherichia coli DNA polymerase I: a two metal ion mechanism (2020) (6)
- Purification, crystallization and preliminary X-ray diffraction analysis of the human mismatch repair protein MutSβ. (2011) (4)
- Crystallization and preliminary diffraction analysis of a hyperthermostable DNA polymerase from a Thermococcus archaeon. (1998) (4)
- Structural Biochemistry of CaaX Protein Prenyltransferases (2011) (3)
- Structures of Protein Farnesyltransferase (2001) (2)
- A Farnesyltransferase Acts to Inhibit Ectopic Neurite Formation in C. elegans (2016) (1)
- Cocrystal structure of Bacillus fragment DNA polymerase I with duplex DNA (open form) (2009) (1)
- Thermotoga maritima maltotriose binding protein, ligand free form (2007) (1)
- Crystal structure of fragment DNA polymerase I from Bacillus stearothermophilus F710Y mutant bound to G:T mismatch (2010) (1)
- Cocrystal structure of Bacillus fragment DNA polymerase I with duplex DNA , dCTP, and zinc (closed form). (2009) (1)
- DNA polymerase crystal (1998) (0)
- Chemical reaction dynamics MINNESOTA-TWIN CITIES (2009) (0)
- Human protein farnesyltransferase complexed with L-778,123 and FPP (2004) (0)
- Thermotoga maritima Ribose Binding Protein Unliganded Form (2007) (0)
- Extension of a cytosine-8-oxoguanine base pair (2004) (0)
- Aminofluorene DNA adduct at the pre-insertion site of a DNA polymerase (2004) (0)
- Thermus thermophilus Glucose/Galactose Binding Protein Bound With Galactose (2006) (0)
- Crystal Structure of Bacillus DNA Polymerase I Large Fragment Bound to DNA and ddATP-dT in Closed Conformation (2011) (0)
- Protein farnesyltransferase complexed with bisubstrate ethylenediamine scaffold inhibitor 5 (2009) (0)
- DNA POLYMERASE FROM THERMOCOCCUS SP. 9ON-7 ARCHAEON (2000) (0)
- Rat Protein Geranylgeranyltransferase Type-I Complexed with a GGPP analog and a substrate KKSKTKCVIF Peptide Derived from TC21 (2004) (0)
- Protein Farnesyltransferase Complexed with a Farnesylated DDPTASACVLS Peptide Product at 1.5A Resolution (2006) (0)
- Protein Geranylgeranyltransferase type-I Complexed with GGPP and a Geranylgeranylated KKKSKTKCVIL Peptide Product (2003) (0)
- Structure of aminofluorene adduct paired opposite cytosine at the polymerase active site. (2004) (0)
- cytosine-8-Oxoguanine base pair at the polymerase active site (2004) (0)
- Candida albicans protein geranylgeranyltransferase-I complexed with GGPP (2008) (0)
- human MutSalpha (MSH2/MSH6) bound to ADP and an O6-methyl-guanine T mispair (2007) (0)
- Crystal Structure of Bacillus DNA Polymerase I Large Fragment Bound to Duplex DNA with Cytosine-Adenine Mismatch at (n-4) Position (2011) (0)
- Structure-Guided Discovery of Potent Antifungals that Prevent Ras Signaling by Inhibiting Protein Farnesyltransferase. (2022) (0)
- Protein Geranylgeranyltransferase type-I Complexed with Geranylgeranyl Diphosphate (2003) (0)
- Structural Studies of Three DNA Binding Proteins: Catabolite Gene Activator Protein, Resolvase, and the Klenow Fragment of DNA Polymerase I (1987) (0)
- Cocrystal structure of an editing complex of Klenow fragment with DNA (2020) (0)
- Crystal structure of human exonuclease 1 Exo1 (WT) in complex with 5' flap DNA (f2II) (2017) (0)
- Crystal structure of human exonuclease 1 Exo1 (D173A) in complex with DNA (complex I) (2011) (0)
- Cryptococcus neoformans protein farnesyltransferase in complex with FSPP and DDPTASACNIQ peptide (2011) (0)
- Thermus thermophilus Glucose/Galactose Binding Protein With Bound Glucose (2006) (0)
- Extension of an adenine-8oxoguanine mismatch (2004) (0)
- A BACILLUS DNA POLYMERASE I PRODUCT COMPLEX BOUND TO A GUANINE-THYMINE MISMATCH AFTER TWO ROUNDS OF PRIMER EXTENSION, FOLLOWING INCORPORATION OF DCTP AND DGTP. (2004) (0)
- Aspergillus fumigatus protein farnesyltransferase ternary complex with farnesyldiphosphate and ethylenediamine scaffold inhibitor 5 (2014) (0)
- Cryptococcus neoformans protein farnesyltransferase in complex with FPP and L-778,123 (2011) (0)
- Bacillus DNA Polymerase I Large Fragment complex 7 (2013) (0)
- Bacillus DNA Polymerase I Large Fragment Complex 1 (2013) (0)
- Adenine-8oxoguanine mismatch at the polymerase active site (2004) (0)
- Ternary complex of Bacillus DNA Polymerase I Large Fragment E658A, DNA duplex, and rCTP (paired with dG of template) in presence of Mg2+ (2012) (0)
- Human Protein Farnesyltransferase Complexed with Inhibitor Compound STN-48 And FPP Analog at 1.8A Resolution (2007) (0)
- Y365F Protein Farnesyltransferase Mutant Complexed with a Farnesylated DDPTASACVLS Peptide Product at 1.8A (2006) (0)
- Crystal Structure of Bacillus DNA Polymerase I Large Fragment Bound to Duplex DNA with Cytosine-Adenine Mismatch at (n-6) Position (2011) (0)
- CRYSTAL STRUCTURE OF RAT PROTEIN FARNESYLTRANSFERASE COMPLEXED WITH THE NON-SUBSTRATE TETRAPEPTIDE INHIBITOR CVFM AND FARNESYL DIPHOSPHATE SUBSTRATE (2001) (0)
- Cryptococcus neoformans protein farnesyltransferase, apo enzyme (2011) (0)
- Ternary complex of Bacillus DNA Polymerase I Large Fragment, DNA duplex, and ddCTP (paired with dG of template) (2012) (0)
- DNA Polymerase I Large Fragment complex 3 (2013) (0)
- DNA Polymerase I Large Fragment complex 4 (2013) (0)
- O6-methyl:C pair in the polymerase-10 basepair position (2006) (0)
- Using time-resolved crystallography and cryo-EM to investigate human DNA repair nucleases (2019) (0)
- Rat protein geranylgeranyltransferase type-I complexed with L-778,123 and a sulfate anion (2004) (0)
- ddCTP:O6MeG pair in the polymerase active site (0 position) (2006) (0)
- O6-methyl-guanine:T pair in the polymerase-10 basepair position (2006) (0)
- Crystal structure of human exonuclease 1 Exo1 (WT) in complex with 5' flap DNA (f5I) (2017) (0)
- PROTEIN FARNESYLTRANSFERASE COMPLEXED WITH A FARNESYLATED K-RAS4B PEPTIDE PRODUCT (2002) (0)
- Crystal structure of human exonuclease 1 Exo1 (WT) in complex with 5' flap DNA (f2I) (2017) (0)
- Crystal Structure of Bacillus DNA Polymerase I Fragment product complex with 12 base pairs of duplex DNA following addition of a dTTP, a dATP, and a dCTP residue. (2003) (0)
- Crystal Structure of Bacillus DNA Polymerase I Large Fragment Bound to DNA and ddCTP-dA Mismatch (wobble) in Ajar Conformation (2011) (0)
- Engineered medium-affinity halide-binding protein derived from YFP: halide-free (2012) (0)
- human MutSalpha (MSH2/MSH6) bound to a G T mispair, with ADP bound to MSH2 only (2007) (0)
- DNA Polymerase I Large Fragment Complex 6 (2013) (0)
- Protein Geranylgeranyltransferase type-I Complexed with a GGPP Analog and a KKKSKTKCVIL Peptide (2003) (0)
- human MutSalpha (MSH2/MSH6) bound to DNA with a single base T insert (2007) (0)
- Cryptococcus neoformans protein farnesyltransferase in complex with FPT-II and tipifarnib (2011) (0)
- Protein farnesyltransferase complexed with FPP and ethylene diamine inhibitor 4 (2009) (0)
- Crystal structure of Aspergillus fumigatus protein farnesyltransferase binary complex with farnesyldiphosphate (2014) (0)
- A BACILLUS DNA POLYMERASE I PRODUCT COMPLEX BOUND TO A CYTOSINE-THYMINE MISMATCH AFTER A SINGLE ROUND OF PRIMER EXTENSION, FOLLOWING INCORPORATION OF DCTP. (2004) (0)
- Rat Protein Geranylgeranyltransferase Type-I Complexed with a GGPP analog and a RRCVLL Peptide Derived from Cdc42 splice isoform-2 (2004) (0)
- Crystal Structure of the Closed Conformation of Bacillus DNA Polymerase I Fragment Bound to DNA and dCTP (2003) (0)
- The Closing Mechanism o f DNA Polymerase I at Atomic Resolution Graphical Abstract Highlights (0)
- Protein Farnesyltransferase Complexed with a H-Ras Peptide Substrate and a FPP Analog at 2.25A Resolution (2004) (0)
- CRYSTAL STRUCTURE OF RAT PROTEIN FARNESYLTRANSFERASE COMPLEXED WITH THE PEPTIDE SUBSTRATE TKCVFM AND AN ANALOG OF FARNESYL DIPHOSPHATE (2001) (0)
- DNA POLYMERASE I/DNA COMPLEX (1999) (0)
- Rat Protein Geranylgeranyltransferase Type-I Complexed with a GGPP analog and a FREKKFFCAIL Peptide Derived from the Heterotrimeric G Protein Gamma-2 Subunit (2004) (0)
- Engineered medium-affinity halide-binding protein derived from YFP: chloride complex (2012) (0)
- Crystal structure of human exonuclease 1 Exo1 (D225A) in complex with 5' recessed-end DNA (rVIII) (2017) (0)
- Bacillus DNA Polymerase I Large Fragment Complex 2 (2013) (0)
- Cryptococcus neoformans protein farnesyltransferase in complex with farnesyl-DDPTASACNIQ product (2011) (0)
- Crystal Structure of Bacillus DNA Polymerase I Large Fragment Bound to DNA and ddCTP-dA Mismatch (tautomer) in Closed Conformation (2011) (0)
- ddTTP:O6-methyl-guanine pair in the polymerase active site, in the closed conformation (2006) (0)
- Crystal Structure of Bacillus DNA Polymerase I Fragment complexed to 9 base pairs of duplex DNA. (1999) (0)
- human protein farnesyltransferase complexed with FPP and R115777 (2004) (0)
- T:O6-methyl-guanine pair in the polymerase postinsertion site (-1 basepair position) (2006) (0)
- Crystal structure of BF DNA polymerase F710Y mutant bound to tetrahydrofuran and dATP (2020) (0)
- Investigation of ATP-induced global motions of the human DNA mismatch repair sensor complex using time-lapse crystallography (2020) (0)
- A Unified Picture of Nucleotide Selection by a High Fidelity DNA Polymerase I (2015) (0)
- Cryptococcus neoformans protein farnesyltransferase in complex with FPT-II and TKCVVM peptide (2011) (0)
- Crystal Structure of Bacillus DNA Polymerase I Large Fragment Bound to Duplex DNA with Cytosine-Adenine Mismatch at (n-1) Position (2011) (0)
- DNA Polymerase I Large Fragment Complex 5 (2013) (0)
- W102T Protein Farnesyltransferase Mutant Complexed with a Geranylgeranylated DDPTASACVLS Peptide Product at 1.85A Resolution (2006) (0)
- human MutSalpha (MSH2/MSH6) bound to ADP and a G dU mispair (2007) (0)
- Rat protein farnesyltransferase complexed with FPP and BMS-214662 (2004) (0)
- Binary complex of Bacillus DNA Polymerase I Large Fragment E658A and duplex DNA (2012) (0)
- Co-Crystal Structure Of Human Farnesyltransferase With Farnesyldiphosphate and Inhibitor Compound 33a (2002) (0)
- O6-methyl-guanine in the polymerase template preinsertion site (2006) (0)
- Crystal Structure of Bacillus DNA Polymerase I Large Fragment Bound to Duplex DNA with Cytosine-Adenine Mismatch at (n-3) Position (2011) (0)
- Crystal structure of human exonuclease 1 Exo1 (WT) in complex with DNA (complex II) (2011) (0)
- Binary complex of Bacillus DNA Polymerase I Large Fragment and duplex DNA with rC in primer terminus paired with dG of template (2012) (0)
- 8oxoguanine at the pre-insertion site of the polymerase active site (2004) (0)
- C:O6-methyl-guanine pair in the polymerase-2 basepair position (2006) (0)
- Zinc-depleted FTase complexed with K-RAS4B peptide substrate and FPP analog. (2000) (0)
- Structures of nascent duplex DNA bound to a thermostable DNA polymerase at 1.9 Å resolution (1996) (0)
- Rat Protein Geranylgeranyltransferase Type-I Complexed with a GGPP analog and a GCINCCKVL Peptide Derived from RhoB (2004) (0)
- CRYSTAL STRUCTURE OF BACILLUS DNA POLYMERASE I FRAGMENT COMPLEXED TO 11 BASE PAIRS OF DUPLEX DNA AFTER ADDITION OF TWO DATP RESIDUES (1999) (0)
- Ternary complex of Bacillus DNA Polymerase I Large Fragment, DNA duplex, and rCTP in presence of Mg2+ (2012) (0)
- Protein farnesyltransferase complexed with FPP and ethylenediamine-scaffold inhibitor 10 (2009) (0)
- W102T/Y365F Protein Farnesyltransferase Double Mutant Complexed with a Geranylgeranylated DDPTASACVLS Peptide Product at 3.0A (2006) (0)
- CRYSTAL STRUCTURE OF HUMAN PROTEIN FARNESYLTRANSFERASE COMPLEXED WITH FARNESYL DIPHOSPHATE AND THE PEPTIDOMIMETIC INHIBITOR L-739,750 (2001) (0)
- Crystal Structures of Human Exonuclease I with DNA Provides Insight into Substrate Selectivity and Mechanism (2011) (0)
- Crystal structure of human exonuclease 1 Exo1 (WT) in complex with DNA and Mn2+ (complex III) (2011) (0)
- BACILLUS STEAROTHERMOPHILUS (NEWLY IDENTIFIED STRAIN AS YET UNNAMED) DNA POLYMERASE FRAGMENT (1997) (0)
- Thermus thermophilus maltotriose binding protein bound with maltotriose (2007) (0)
- Crystal structure of Aspergillus fumigatus protein farnesyltransferase complexed with the FII analog, FPT-II, and the KCVVM peptide (2014) (0)
- Thermotoga maritima maltotriose binding protein bound with maltotriose. (2007) (0)
- A BACILLUS DNA POLYMERASE I PRODUCT COMPLEX BOUND TO A GUANINE-THYMINE MISMATCH AFTER THREE ROUNDS OF PRIMER EXTENSION, FOLLOWING INCORPORATION OF DCTP, DGTP, AND DTTP. (2004) (0)
- Protein farnesyltransferase complexed with FPP and caged TKCVIM substrate (2008) (0)
- A BACILLUS DNA POLYMERASE I PRODUCT COMPLEX BOUND TO A GUANINE-THYMINE MISMATCH AFTER FIVE ROUNDS OF PRIMER EXTENSION, FOLLOWING INCORPORATION OF DCTP, DGTP, DTTP, AND DATP. (2004) (0)
- Rat Protein Geranylgeranyltransferase Type-I Complexed with a GGPP analog and a KKKSKTKCVIM Peptide Derived from K-Ras4B (2004) (0)
- STRUCTURE OF RAT FARNESYL PROTEIN TRANSFERASE COMPLEXED WITH A CVIM PEPTIDE AND ALPHA-HYDROXYFARNESYLPHOSPHONIC ACID. (1999) (0)
- Crystal structure of fragment DNA polymerase I from Bacillus stearothermophilus V713P mutant bound to G:dCTP (2010) (0)
- CO-CRYSTAL STRUCTURE OF RAT PROTEIN FARNESYLTRANSFERASE COMPLEXED WITH A K-RAS4B PEPTIDE SUBSTRATE AND FPP ANALOG AT 2.0A RESOLUTION (2000) (0)
- PROTEIN FARNESYLTRANSFERASE COMPLEXED WITH FARNESYLATED K-RAS4B PEPTIDE PRODUCT AND FARNESYL DIPHOSPHATE SUBSTRATE BOUND SIMULTANEOUSLY (2002) (0)
- Aspergillus fumigatus protein farnesyltransferase complex with farnesyldiphosphate and tipifarnib (2014) (0)
- Transition State Model of the Protein Farnesyltransferase Reaction Based on Crystal Structures of Protein Farnesyltransferase With Bound Substrates and Products (2002) (0)
- Crystallization and preliminary characterization of a hyperthermostable archeal DNA polymerase (1996) (0)
- Cryptococcus neoformans protein farnesyltransferase in complex with FPT-II and ethylenediamine inhibitor 2 (2011) (0)
- Structure-guided design of Cryptococcus neoformans protein farnesyltransferase inhibitors with antifungal activity (2021) (0)
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