Lorenzo Moretta

Q: What Schools Are Affiliated With Lorenzo Moretta

Lorenzo Moretta is affiliated with the following schools: University of California, Berkeley, University of Perugia, Stanford University, University of Toronto, University of Genoa, Harvard University

Lorenzo Moretta's AcademicInfluence.com Rankings

Lorenzo Moretta

Computer Science

#2685

World Rank

#2809

Historical Rank

Computational Linguistics

#48

World Rank

#49

Historical Rank

Machine Learning

#185

World Rank

#187

Historical Rank

Artificial Intelligence

#320

World Rank

#326

Historical Rank

computer-science Degrees

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Computer Science

Lorenzo Moretta's Degrees

Masters Artificial Intelligence Stanford University
Bachelors Computer Science University of California, Berkeley

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Lorenzo Moretta's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Mesenchymal stem cells in health and disease (2008) (3126)
Activating receptors and coreceptors involved in human natural killer cell-mediated cytolysis. (2001) (1872)
Functional analysis of two human T-cell subpopulations: help and suppression of B-cell responses by T cells bearing receptors for IgM or IgG (1977) (1079)
Human Dendritic Cells Activate Resting Natural Killer (NK) Cells and Are Recognized via the NKp30 Receptor by Activated NK Cells (2002) (1079)
Mesenchymal stem cell-natural killer cell interactions: evidence that activated NK cells are capable of killing MSCs, whereas MSCs can inhibit IL-2-induced NK-cell proliferation. (2006) (1011)
Mesenchymal stem cells inhibit natural killer-cell proliferation, cytotoxicity, and cytokine production: role of indoleamine 2,3-dioxygenase and prostaglandin E2. (2008) (986)
Receptors for HLA class-I molecules in human natural killer cells. (1996) (900)
Identification of PVR (CD155) and Nectin-2 (CD112) as Cell Surface Ligands for the Human DNAM-1 (CD226) Activating Molecule (2003) (809)
Identification and Molecular Characterization of Nkp30, a Novel Triggering Receptor Involved in Natural Cytotoxicity Mediated by Human Natural Killer Cells (1999) (801)
NKp44, a Novel Triggering Surface Molecule Specifically Expressed by Activated Natural Killer Cells, Is Involved in Non–Major Histocompatibility Complex–restricted Tumor Cell Lysis (1998) (791)
MSCs inhibit monocyte-derived DC maturation and function by selectively interfering with the generation of immature DCs: central role of MSC-derived prostaglandin E2. (2009) (628)
Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition) (2019) (627)
Unravelling natural killer cell function: triggering and inhibitory human NK receptors (2004) (623)
Transforming growth factor β1 inhibits expression of NKp30 and NKG2D receptors: Consequences for the NK-mediated killing of dendritic cells (2003) (622)
Molecular clones of the p58 NK cell receptor reveal immunoglobulin-related molecules with diversity in both the extra- and intracellular domains. (1995) (617)
Molecular Cloning of NKp46: A Novel Member of the Immunoglobulin Superfamily Involved in Triggering of Natural Cytotoxicity (1998) (609)
Distinct roles of IL-12 and IL-15 in human natural killer cell activation by dendritic cells from secondary lymphoid organs. (2004) (583)
P58 molecules as putative receptors for major histocompatibility complex (MHC) class I molecules in human natural killer (NK) cells. Anti-p58 antibodies reconstitute lysis of MHC class I-protected cells in NK clones displaying different specificities (1993) (569)
p46, a Novel Natural Killer Cell–specific Surface Molecule That Mediates Cell Activation (1997) (556)
Major histocompatibility complex class I-related chain A and UL16-binding protein expression on tumor cell lines of different histotypes: analysis of tumor susceptibility to NKG2D-dependent natural killer cell cytotoxicity. (2002) (547)
Guidelines for the use of flow cytometry and cell sorting in immunological studies (2017) (520)
COVID-19 vaccines: where we stand and challenges ahead (2021) (510)
Existence of both inhibitory (p58) and activatory (p50) receptors for HLA-C molecules in human natural killer cells (1995) (483)
X-Linked Lymphoproliferative Disease 2b4 Molecules Displaying Inhibitory Rather than Activating Function Are Responsible for the Inability of Natural Killer Cells to Kill Epstein-Barr Virus–Infected Cells (2000) (483)
CpG and double-stranded RNA trigger human NK cells by Toll-like receptors: induction of cytokine release and cytotoxicity against tumors and dendritic cells. (2004) (476)
NKp44, A Triggering Receptor Involved in Tumor Cell Lysis by Activated Human Natural Killer Cells, Is a Novel Member of the Immunoglobulin Superfamily (1999) (475)
What is a natural killer cell? (2002) (468)
CD56brightCD16− Killer Ig-Like Receptor− NK Cells Display Longer Telomeres and Acquire Features of CD56dim NK Cells upon Activation1 (2007) (461)
NKp46 is the major triggering receptor involved in the natural cytotoxicity of fresh or cultured human NK cells. Correlation between surface density of NKp46 and natural cytotoxicity against autologous, allogeneic or xenogeneic target cells (1999) (456)
Mesenchymal stem cells inhibit natural killer – cell proliferation , cytotoxicity , and cytokine production : role of indoleamine 2 , 3-dioxygenase and prostaglandin E 2 (2008) (449)
Mesenchymal stem cells: a new strategy for immunosuppression? (2007) (444)
Immunoregulatory function of mesenchymal stem cells (2006) (439)
Killer immunoglobulin-like receptors. (2004) (432)
Natural cytotoxicity receptors that trigger human NK-cell-mediated cytolysis. (2000) (401)
Human T lymphocyte subpopulations defined by Fc receptors and monoclonal antibodies. A comparison (1980) (397)
Natural killer cells in HIV-1 infection: Dichotomous effects of viremia on inhibitory and activating receptors and their functional correlates (2003) (394)
Inhibitory receptors sensing HLA-G1 molecules in pregnancy: decidua-associated natural killer cells express LIR-1 and CD94/NKG2A and acquire p49, an HLA-G1-specific receptor. (1999) (394)
The natural killer cell receptor specific for HLA-A allotypes: a novel member of the p58/p70 family of inhibitory receptors that is characterized by three immunoglobulin-like domains and is expressed as a 140-kD disulphide-linked dimer (1996) (392)
Major histocompatibility complex class I‐specific receptors on human natural killer and T lymphocytes (1997) (382)
Role of NKG2D in tumor cell lysis mediated by human NK cells: cooperation with natural cytotoxicity receptors and capability of recognizing tumors of nonepithelial origin (2001) (382)
Anti-leukemia activity of alloreactive NK cells in KIR ligand-mismatched haploidentical HSCT for pediatric patients: evaluation of the functional role of activating KIR and redefinition of inhibitory KIR specificity. (2009) (380)
Human and mouse killer-cell inhibitory receptors recruit PTP1C and PTP1D protein tyrosine phosphatases. (1996) (380)
Subpopulations of human T cells identified by receptors for immunoglobulins and mitogen responsiveness. (1976) (372)
Expression of a receptor for IgM by human T cells in vitro (1975) (371)
NK-dependent DC maturation is mediated by TNFα and IFNγ released upon engagement of the NKp30 triggering receptor (2005) (366)
Human interleukin-2 promotes proliferation of activated B cells via surface receptors similar to those of activated T cells (1984) (364)
Analysis of the receptor-ligand interactions in the natural killer-mediated lysis of freshly isolated myeloid or lymphoblastic leukemias: evidence for the involvement of the Poliovirus receptor (CD155) and Nectin-2 (CD112). (2005) (363)
HLA-haploidentical stem cell transplantation after removal of αβ+ T and B cells in children with nonmalignant disorders. (2014) (362)
Classification of current anticancer immunotherapies (2014) (357)
NK cells at the interface between innate and adaptive immunity (2008) (356)
The human leukocyte antigen (HLA)-C-specific "activatory" or "inhibitory" natural killer cell receptors display highly homologous extracellular domains but differ in their transmembrane and intracytoplasmic portions (1996) (352)
Natural killer cells infiltrating human nonsmall‐cell lung cancer are enriched in CD56brightCD16− cells and display an impaired capability to kill tumor cells (2008) (343)
Direct demonstration of the clonogenic potential of every human peripheral blood T cell. Clonal analysis of HLA-DR expression and cytolytic activity (1983) (340)
Identification of a subset of human natural killer cells expressing high levels of programmed death 1: A phenotypic and functional characterization (2017) (334)
Revisiting human natural killer cell subset function revealed cytolytic CD56dimCD16+ NK cells as rapid producers of abundant IFN-γ on activation (2010) (334)
The impaired NK cell cytolytic function in viremic HIV‐1 infection is associated with a reduced surface expression of natural cytotoxicity receptors (NKp46, NKp30 and NKp44) (2003) (322)
NTB-A [correction of GNTB-A], a novel SH2D1A-associated surface molecule contributing to the inability of natural killer cells to kill Epstein-Barr virus-infected B cells in X-linked lymphoproliferative disease. (2001) (322)
Effector and regulatory events during natural killer–dendritic cell interactions (2006) (313)
Morphological and histochemical analyses of two human T-cell subpopulations bearing receptors for IgM or IgG (1978) (313)
The tryptophan catabolite L-kynurenine inhibits the surface expression of NKp46- and NKG2D-activating receptors and regulates NK-cell function. (2006) (308)
Effect of tumor cells and tumor microenvironment on NK‐cell function (2014) (302)
The natural killer cell‐mediated killing of autologous dendritic cells is confined to a cell subset expressing CD94/NKG2A, but lacking inhibitory killer Ig‐like receptors (2003) (289)
Surface NK receptors and their ligands on tumor cells. (2006) (289)
The CD94 and NKG2‐A C‐type lectins covalently assemble to form a natural killer cell inhibitory receptor for HLA class I molecules (1997) (288)
NK Cells Recognize and Kill Human Glioblastoma Cells with Stem Cell-Like Properties1 (2009) (286)
Human CD8+ T lymphocyte subsets that express HLA class I-specific inhibitory receptors represent oligoclonally or monoclonally expanded cell populations. (1996) (283)
Regulation of KIR expression in human T cells: a safety mechanism that may impair protective T-cell responses. (1998) (279)
Bone Marrow‐Derived Mesenchymal Stem Cells Induce Both Polyclonal Expansion and Differentiation of B Cells Isolated from Healthy Donors and Systemic Lupus Erythematosus Patients (2008) (279)
Receptors for IgG molecules on human lymphocytes forming spontaneous rosettes with sheep red cells (1975) (268)
A novel surface antigen expressed by a subset of human CD3- CD16+ natural killer cells. Role in cell activation and regulation of cytolytic function (1990) (264)
Melanoma cells inhibit natural killer cell function by modulating the expression of activating receptors and cytolytic activity. (2012) (264)
Expression of the DNAM-1 ligands, Nectin-2 (CD112) and poliovirus receptor (CD155), on dendritic cells: relevance for natural killer-dendritic cell interaction. (2006) (262)
A prospective evaluation of degranulation assays in the rapid diagnosis of familial hemophagocytic syndromes. (2012) (260)
Identification of 4Ig-B7-H3 as a neuroblastoma-associated molecule that exerts a protective role from an NK cell-mediated lysis. (2004) (257)
Melanoma-associated fibroblasts modulate NK cell phenotype and antitumor cytotoxicity (2009) (252)
Cellular ligands of activating NK receptors. (2005) (250)
HLA class I-specific inhibitory receptors in human T lymphocytes: interleukin 15-induced expression of CD94/NKG2A in superantigen- or alloantigen-activated CD8+ T cells. (1998) (249)
Human natural killer cells: their origin, receptors and function (2002) (248)
2B4 functions as a co‐receptor in human NK cell activation (2000) (245)
NK-dependent DC maturation is mediated by TNFalpha and IFNgamma released upon engagement of the NKp30 triggering receptor. (2005) (242)
Phenotypic and functional heterogeneity of human NK cells developing after umbilical cord blood transplantation: a role for human cytomegalovirus? (2012) (238)
Role of amino acid position 70 in the binding affinity of p50.1 and p58.1 receptors for HLA‐Cw4 molecules (1997) (237)
The interaction between NK cells and dendritic cells in bacterial infections results in rapid induction of NK cell activation and in the lysis of uninfected dendritic cells (2003) (233)
CD69-mediated pathway of lymphocyte activation: anti-CD69 monoclonal antibodies trigger the cytolytic activity of different lymphoid effector cells with the exception of cytolytic T lymphocytes expressing T cell receptor alpha/beta (1991) (229)
Human NK cells: surface receptors, inhibitory checkpoints, and translational applications (2019) (228)
Human natural killer cells: origin, clonality, specificity, and receptors. (1994) (226)
Killer Ig-like receptor-mediated control of natural killer cell alloreactivity in haploidentical hematopoietic stem cell transplantation. (2011) (226)
Outcome of children with acute leukemia given HLA-haploidentical HSCT after αβ T-cell and B-cell depletion. (2017) (225)
Identification and Molecular Cloning of P75/Airm1, a Novel Member of the Sialoadhesin Family That Functions as an Inhibitory Receptor in Human Natural Killer Cells (1999) (223)
Increased natural cytotoxicity receptor expression and relevant IL‐10 production in NK cells from chronically infected viremic HCV patients (2007) (220)
The small subset of CD56brightCD16– natural killer cells is selectively responsible for both cell proliferation and interferon‐γ production upon interaction with dendritic cells (2004) (216)
Crosstalk between decidual NK and CD14+ myelomonocytic cells results in induction of Tregs and immunosuppression (2010) (215)
Early expression of triggering receptors and regulatory role of 2B4 in human natural killer cell precursors undergoing in vitro differentiation (2002) (215)
Amino acid substitutions can influence the natural killer (NK)-mediated recognition of HLA-C molecules. Role of serine-77 and lysine-80 in the target cell protection from lysis mediated by "group 2" or "group 1" NK clones (1995) (212)
The Nrf2/HO-1 Axis in Cancer Cell Growth and Chemoresistance (2015) (212)
Distribution of T cells bearing different forms of the T cell receptor gamma/delta in normal and pathological human tissues. (1989) (210)
Identification of NKp80, a novel triggering molecule expressed by human NK cells (2001) (205)
The interaction of human natural killer cells with either unpolarized or polarized macrophages results in different functional outcomes (2010) (202)
γδ T-cell reconstitution after HLA-haploidentical hematopoietic transplantation depleted of TCR-αβ+/CD19+ lymphocytes. (2015) (202)
Pathogenesis of haemophagocytic lymphohistiocytosis (2001) (202)
Human natural killer cell receptors for HLA-class I molecules. Evidence that the Kp43 (CD94) molecule functions as receptor for HLA-B alleles (1994) (199)
Killer Ig-Like Receptors (KIRs): Their Role in NK Cell Modulation and Developments Leading to Their Clinical Exploitation (2019) (193)
Evidence of a natural killer (NK) cell repertoire for (allo) antigen recognition: definition of five distinct NK-determined allospecificities in humans (1992) (192)
Hypoxia downregulates the expression of activating receptors involved in NK‐cell‐mediated target cell killing without affecting ADCC (2013) (192)
Human NK-cell receptors. (2000) (192)
NCR+ILC3 concentrate in human lung cancer and associate with intratumoral lymphoid structures (2015) (190)
HLA-E-restricted recognition of cytomegalovirus-derived peptides by human CD8+ cytolytic T lymphocytes (2003) (190)
CD34+ hematopoietic precursors are present in human decidua and differentiate into natural killer cells upon interaction with stromal cells (2011) (190)
Allorecognition by NK cells: nonself or no self? (1992) (187)
Dual-functional capability of CD3+CD56+ CIK cells, a T-cell subset that acquires NK function and retains TCR-mediated specific cytotoxicity. (2011) (186)
The murine homologue of the human NKp46, a triggering receptor involved in the induction of natural cytotoxicity (1999) (185)
IL‐21 induces both rapid maturation of human CD34+ cell precursors towards NK cells and acquisition of surface killer Ig‐like receptors (2003) (185)
Interleukin‐15‐induced maturation of human natural killer cells from early thymic precursors: selective expression of CD94/NKG2‐A as the only HLA class I‐specific inhibitory receptor (1997) (182)
Adult onset and atypical presentation of hemophagocytic lymphohistiocytosis in siblings carrying PRF1 mutations. (2002) (182)
Two subsets of human T lymphocytes expressing gamma/delta antigen receptor are identifiable by monoclonal antibodies directed to two distinct molecular forms of the receptor (1988) (181)
Analysis of natural killer-cell function in familial hemophagocytic lymphohistiocytosis (FHL): defective CD107a surface expression heralds Munc13-4 defect and discriminates between genetic subtypes of the disease. (2006) (179)
Natural Killer Cell-Mediated Killing of Freshly Isolated Neuroblastoma Cells (2004) (178)
p49, a putative HLA class I‐specific inhibitory NK receptor belonging to the immunoglobulin superfamily (1998) (176)
Transforming growth factor‐β‐induced expression of CD94/NKG2A inhibitory receptors in human T lymphocytes (1999) (176)
Early liaisons between cells of the innate immune system in inflamed peripheral tissues. (2005) (173)
CD56brightPerforinlow Noncytotoxic Human NK Cells Are Abundant in Both Healthy and Neoplastic Solid Tissues and Recirculate to Secondary Lymphoid Organs via Afferent Lymph (2014) (172)
Alloantigen recognition by two human natural killer cell clones is associated with HLA-C or a closely linked gene. (1992) (169)
T cell clones expressing the natural killer cell‐related p58 receptor molecule display heterogeneity in phenotypic properties and p58 function (1994) (169)
Different checkpoints in human NK-cell activation. (2004) (166)
Occurrence of human immunodeficiency virus type 1 (HIV-1)-specific cytolytic T cell activity in apparently uninfected children born to HIV-1-infected mothers. (1994) (165)
Activation of human NK cells by plasmacytoid dendritic cells and its modulation by CD4+ T helper cells and CD4+ CD25hi T regulatory cells (2005) (161)
Molecular and functional characterization of IRp60, a member of the immunoglobulin superfamily that functions as an inhibitory receptor in human NK cells (1999) (160)
Interferon-γ-dependent inhibition of B cell activation by bone marrow-derived mesenchymal stem cells in a murine model of systemic lupus erythematosus. (2010) (159)
Human Cytomegalovirus Infection Promotes Rapid Maturation of NK Cells Expressing Activating Killer Ig–like Receptor in Patients Transplanted with NKG2C−/− Umbilical Cord Blood (2014) (159)
Control of self‐reactive cytotoxic T lymphocytes expressing γδ T cell receptors by natural killer inhibitory receptors (1997) (157)
Human NK cell receptors/markers: A tool to analyze NK cell development, subsets and function (2013) (155)
Engagement of p75/AIRM1 or CD33 inhibits the proliferation of normal or leukemic myeloid cells. (1999) (152)
The Inhibitory Receptor IRp60 (CD300a) Is Expressed and Functional on Human Mast Cells1 (2005) (151)
NK cell‐mediated lysis of autologous antigen‐presenting cells is triggered by the engagement of the phosphatidylinositol 3‐kinase upon ligation of the natural cytotoxicity receptors NKp30 and NKp46 (2001) (149)
KIR3DS1-Mediated Recognition of HLA-*B51: Modulation of KIR3DS1 Responsiveness by Self HLA-B Allotypes and Effect on NK Cell Licensing (2017) (146)
Separation, phenotyping and limiting dilution analysis of T‐lymphocytes infiltrating human solid tumors (1986) (146)
HO-1 Induction in Cancer Progression: A Matter of Cell Adaptation (2017) (145)
Clonal and frequency analyses of tumor-infiltrating T lymphocytes from human solid tumors. (1987) (144)
Origin, phenotype and function of human natural killer cells in pregnancy. (2011) (144)
HLA class I specific inhibitory receptors. (1997) (142)
Active thymus derived suppressor lymphocytes in human cord blood (1977) (142)
IL-12 or IL-4 Prime Human NK Cells to Mediate Functionally Divergent Interactions with Dendritic Cells or Tumors1 (2005) (142)
Dissecting CD56dim human NK cells. (2010) (141)
The inhibitory receptor IRp60 (CD300a) suppresses the effects of IL-5, GM-CSF, and eotaxin on human peripheral blood eosinophils. (2006) (140)
Human natural killer cells exposed to IL-2, IL-12, IL-18, or IL-4 differently modulate priming of naive T cells by monocyte-derived dendritic cells. (2008) (140)
Natural killer cells kill human melanoma cells with characteristics of cancer stem cells. (2009) (139)
CD94 functions as a natural killer cell inhibitory receptor for different HLA class I alleles: identification of the inhibitory form of CD94 by the use of novel monoclonal antibodies (1996) (137)
The leukocyte Ig-like receptor (LIR)-1 for the cytomegalovirus UL18 protein displays a broad specificity for different HLA class I alleles: analysis of LIR-1 + NK cell clones. (1999) (136)
Human natural killer cells: Molecular mechanisms controlling NK cell activation and tumor cell lysis. (2005) (136)
Involvement of T44 molecules in an antigen-independent pathway of T cell activation. Analysis of the correlations to the T cell antigen- receptor complex (1985) (136)
Control of B cell lymphoma recognition via natural killer inhibitory receptors implies a role for human Vγ9/Vδ2 T cells in tumor immunity (1997) (135)
Loss of Fc receptors for IgG from human T lymphocytes exposed to IgG immune complexes (1978) (134)
Mesenchymal Stromal Cells Induce Peculiar Alternatively Activated Macrophages Capable of Dampening Both Innate and Adaptive Immune Responses (2016) (133)
A novel surface molecule homologous to the p58/p50 family of receptors is selectively expressed on a subset of human natural killer cells and induces both triggering of cell functions and proliferation (1996) (132)
Reconstituted Killer Cell Inhibitory Receptors for Major Histocompatibility Complex Class I Molecules Control Mast Cell Activation Induced via Immunoreceptor Tyrosine-based Activation Motifs* (1997) (130)
Significant NK cell activation associated with decreased cytolytic function in peripheral blood of HIV‐1‐infected patients (2004) (130)
Identification of diverse innate lymphoid cells in human decidua (2014) (129)
PVR (CD155) and Nectin-2 (CD112) as ligands of the human DNAM-1 (CD226) activating receptor: involvement in tumor cell lysis. (2005) (128)
Transmembrane signalling via the T11‐dependent pathway of human T cell activation. Evidence for the involvement of 1,2‐diacylglycerol and inositol phosphates (1987) (128)
Quantitative assessment of the pool size and subset distribution of cytolytic T lymphocytes within human resting or alloactivated peripheral blood T cell populations (1983) (128)
Neuroblastoma-Derived TGF-β1 Modulates the Chemokine Receptor Repertoire of Human Resting NK Cells (2013) (125)
Human RORγt(+)CD34(+) cells are lineage-specified progenitors of group 3 RORγt(+) innate lymphoid cells. (2014) (124)
KIR B haplotype donors confer a reduced risk for relapse after haploidentical transplantation in children with ALL. (2014) (124)
Analysis of natural killer cells isolated from human decidua: Evidence that 2B4 (CD244) functions as an inhibitory receptor and blocks NK-cell function. (2006) (124)
Surface markers of cloned human T cells with various cytolytic activities (1981) (123)
Human NK cells directly recognize Mycobacterium bovis via TLR2 and acquire the ability to kill monocyte-derived DC. (2008) (123)
Diversity and structure of human T cell receptor delta chain genes in peripheral blood gamma/delta-bearing T lymphocytes (1989) (123)
Human Natural Killer Cells: Origin, Receptors, Function, and Clinical Applications (2014) (122)
PD‐L1 Expression Heterogeneity in Non–Small Cell Lung Cancer: Defining Criteria for Harmonization between Biopsy Specimens and Whole Sections (2018) (120)
Immune suppression of hematopoiesis in aplastic anemia: activity of T-gamma lymphocytes. (1980) (120)
Genetic predisposition to hemophagocytic lymphohistiocytosis: Report on 500 patients from the Italian registry (2016) (119)
Human NK cells: from HLA class I‐specific killer Ig‐like receptors to the therapy of acute leukemias (2008) (119)
Physical and functional independency of p70 and p58 natural killer (NK) cell receptors for HLA class I: their role in the definition of different groups of alloreactive NK cell clones. (1996) (118)
Structural basis for a major histocompatibility complex class Ib–restricted T cell response (2006) (116)
Characterization of human T-cell subpopulations as defined by specific receptors for immunoglobulins. (1978) (116)
PD/1-PD-Ls Checkpoint: Insight on the Potential Role of NK Cells (2019) (116)
Specific lysis of allogeneic cells after activation of CD3- lymphocytes in mixed lymphocyte culture (1988) (115)
Expression of HLA class I-specific inhibitory natural killer cell receptors in HIV-specific cytolytic T lymphocytes: impairment of specific cytolytic functions. (1997) (115)
Mesenchymal stem cells expanded in human platelet lysate display a decreased inhibitory capacity on T‐ and NK‐cell proliferation and function (2011) (113)
Regulatory role of NKp44, NKp46, DNAM-1 and NKG2D receptors in the interaction between NK cells and trophoblast cells. Evidence for divergent functional profiles of decidual versus peripheral NK cells. (2008) (111)
Human Natural Killer cell receptors: insights into their molecular function and structure (2003) (111)
Imbalances in T cell subpopulations associated with immunodeficiency and autoimmune syndromes (1977) (109)
Homophilic interaction of NTBA, a member of the CD2 molecular family: induction of cytotoxicity and cytokine release in human NK cells (2004) (109)
Selective Increase of a Subset of T Cell Receptor γδ T Lymphocytes in the Peripheral Blood of Patients with Human Immunodeficiency Virus Type 1 Infection (1992) (108)
Natural killer cells expressing the KIR2DS1-activating receptor efficiently kill T-cell blasts and dendritic cells: implications in haploidentical HSCT. (2011) (108)
Cellular and molecular basis of haploidentical hematopoietic stem cell transplantation in the successful treatment of high-risk leukemias: role of alloreactive NK cells (2013) (108)
Fc-receptor heterogeneity of human suppressor T cells. (1978) (108)
The three-dimensional structure of the human NK cell receptor NKp44, a triggering partner in natural cytotoxicity. (2003) (107)
Human T lymphocyte subpopulations: studies of the mechanism by which T cells bearing Fc receptors for IgG suppress T-dependent B cell differentiation induced by pokeweed mitogen. (1979) (107)
A monoclonal antibody specific for a common determinant of the human T cell receptor gamma/delta directly activates CD3+WT31- lymphocytes to express their functional program(s) (1988) (107)
The activating form of CD94 receptor complex: CD94 covalently associated with the Kp39 protein that represents the product of the NKG2‐C gene (1998) (106)
A novel KIR-associated function: evidence that CpG DNA uptake and shuttling to early endosomes is mediated by KIR3DL2. (2010) (106)
NK Cells Mediate a Crucial Graft-versus-Leukemia Effect in Haploidentical-HSCT to Cure High-Risk Acute Leukemia. (2018) (106)
2B4 (CD244) Is Expressed and Functional on Human Eosinophils1 (2005) (106)
New nomenclature for MHC receptors (2001) (105)
Surface expression and function of p75/AIRM-1 or CD33 in acute myeloid leukemias: Engagement of CD33 induces apoptosis of leukemic cells (2001) (104)
COVID-19: Unanswered questions on immune response and pathogenesis (2020) (102)
The human natural cytotoxicity receptors (NCR) that induce HLA class I-independent NK cell triggering. (2000) (102)
Dendritic Cell Editing by Activated Natural Killer Cells Results in a More Protective Cancer-Specific Immune Response (2012) (101)
Analysis of the molecular mechanism involved in 2B4‐mediated NK cell activation: evidence that human 2B4 is physically and functionally associated with the linker for activation of T cells (2000) (100)
Human NK Cells Induce Neutrophil Apoptosis via an NKp46- and Fas-Dependent Mechanism (2012) (100)
Cellular and molecular interactions of mesenchymal stem cells in innate immunity (2013) (100)
NK-CTLs, a novel HLA-E-restricted T-cell subset. (2003) (100)
Melanoma cells become resistant to NK‐cell‐mediated killing when exposed to NK‐cell numbers compatible with NK‐cell infiltration in the tumor (2012) (99)
Selective cross‐talk among natural cytotoxicity receptors in human natural killer cells (2003) (99)
Self class I molecules protect normal cells from lysis mediated by autologous natural killer cells (1994) (99)
NK cells: a lesson from mismatched hematopoietic transplantation. (2002) (99)
The analysis of the natural killer‐like activity of human cytolytic T lymphocytes revealed HLA‐E as a novel target for TCR α/β‐mediated recognition (2001) (98)
A single amino acid change, A91V, leads to conformational changes that can impair processing to the active form of perforin. (2005) (98)
Unique Eomes+ NK Cell Subsets Are Present in Uterus and Decidua During Early Pregnancy (2016) (98)
Identification of HLA-E-specific alloreactive T lymphocytes: A cell subset that undergoes preferential expansion in mixed lymphocyte culture and displays a broad cytolytic activity against allogeneic cells (2002) (98)
Human γδT Cells that Inhibit the In Vitro Growth of the Asexual Blood Stages of the Plasmodium falciparum Parasite Express Cytolytic and Proinflammatory Molecules (1999) (97)
Polymorphism in Human Cytomegalovirus UL40 Impacts on Recognition of Human Leukocyte Antigen-E (HLA-E) by Natural Killer Cells* (2013) (95)
Imbalances in T cell subpopulations in multiple sclerosis patients. (1978) (95)
In vitro proliferation and cloning of CD3- CD16+ cells from human thymocyte precursors (1991) (94)
Human T Cell Subpopulations in Normal and Pathologic Conditions (1979) (94)
Imbalances of T cell subpopulations in patients with atopic diseases and effect of specific immunotherapy. (1979) (93)
Specific recognition of human CD3-CD16+ natural killer cells requires the expression of an autosomic recessive gene on target cells (1990) (92)
The Emerging Role of HLA-E-Restricted CD8+ T Lymphocytes in the Adaptive Immune Response to Pathogens and Tumors (2010) (91)
Recognition of virus-infected cells by natural killer cell clones is controlled by polymorphic target cell elements (1993) (91)
p40/LAIR‐1 regulates the differentiation of peripheral blood precursors to dendritic cells induced by granulocyte‐monocyte colony‐stimulating factor (1998) (91)
Uptake of CCR7 and acquisition of migratory properties by human KIR+ NK cells interacting with monocyte-derived DC or EBV cell lines: regulation by KIR/HLA-class I interaction. (2009) (91)
Functional analysis of cloned germinal center CD4+ cells with natural killer cell-related features. Divergence from typical T helper cells. (1986) (90)
B cell growth factor activity of interferon-gamma. Recombinant human interferon-gamma promotes proliferation of anti-mu-activated human B lymphocytes. (1986) (90)
Multidirectional interactions are bridging human NK cells with plasmacytoid and monocyte-derived dendritic cells during innate immune responses. (2006) (90)
HLA‐G recognition by human natural killer cells. Involvement of CD94 both as inhibitory and as activating receptor complex (1997) (89)
Effect Of Human Natural Killer and γδ T Cells on the Growth of Human Autologous Melanoma Xenografts in SCID Mice (2004) (89)
Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition) (2021) (89)
Tp44 molecules involved in antigen-independent T cell activation are expressed on human plasma cells. (1987) (87)
Human natural killer cell function and receptors. (2001) (86)
PD-L1 expression in metastatic neuroblastoma as an additional mechanism for limiting immune surveillance (2016) (86)
Learning how to discriminate between friends and enemies, a lesson from Natural Killer cells. (2004) (86)
T.6. Mesenchymal Stem Cells Inhibit Natural Killer Cell Proliferation, Cytotoxicity and Cytokine Production: Role of Indoleamine 2,3-Dioxygenase and Prostaglandin E2 (2009) (86)
Identification of PVR ( CD 155 ) and Nectin-2 ( CD 112 ) as Cell Surface Ligands for the Human DNAM-1 ( CD 226 ) Activating Molecule (2003) (85)
Human NK cells and their receptors. (2002) (85)
Mutant EL-4 thymoma cells polyclonally activate murine and human B cells via direct cell interaction. (1985) (85)
Clonal heterogeneity in the requirement for T3, T4, and T8 molecules in human cytolytic T lymphocyte function (1984) (85)
Human T cell subpopulations defined by a monoclonal antibody. I. A small subset is responsible for proliferation to allogeneic cells or to soluble antigens and for helper activity for B cell differentiation. (1982) (84)
p40, a novel surface molecule involved in the regulation of the non‐major histocompatibility complex‐restricted cytolytic activity in humans (1995) (84)
Selection and characterization of T-cell variants lacking molecules involved in T-cell activation (T3 T-cell receptor, T44, and T11): analysis of the functional relationship among different pathways of activation. (1987) (83)
PD-L1 expression heterogeneity in non-small cell lung cancer: evaluation of small biopsies reliability (2017) (82)
NK cells and ILCs in tumor immunotherapy. (2020) (82)
M‐CSF induces the expression of a membrane‐bound form of IL‐18 in a subset of human monocytes differentiating in vitro toward macrophages (2012) (82)
TLR activation of tumor‐associated macrophages from ovarian cancer patients triggers cytolytic activity of NK cells (2014) (81)
Novel Munc13–4 mutations in children and young adult patients with haemophagocytic lymphohistiocytosis (2006) (81)
CLONAL ANALYSIS OF T LYMPHOCYTES ISOLATED FROM OVARIAN CARCINOMA ASCITIC FLUID. PHENOTYPIC AND FUNCTIONAL CHARACTERIZATION OF T‐CELL CLONES CAPABLE OF LYSING AUTOLOGOUS CARCINOMA CELLS (1985) (81)
CD59 is physically and functionally associated with natural cytotoxicity receptors and activates human NK cell‐mediated cytotoxicity (2003) (81)
Activating NK cell receptor expression/function (NKp30, NKp46, DNAM‐1) during chronic viraemic HCV infection is associated with the outcome of combined treatment (2011) (80)
Hypoxia Modifies the Transcriptome of Human NK Cells, Modulates Their Immunoregulatory Profile, and Influences NK Cell Subset Migration (2018) (80)
Analysis of memory-like natural killer cells in human cytomegalovirus-infected children undergoing αβ+T and B cell-depleted hematopoietic stem cell transplantation for hematological malignancies (2016) (80)
Analysis of natural killer cells in TAP2-deficient patients: expression of functional triggering receptors and evidence for the existence of inhibitory receptor(s) that prevent lysis of normal autologous cells. (2002) (80)
Molecular analysis of the methylprednisolone-mediated inhibition of NK-cell function: evidence for different susceptibility of IL-2- versus IL-15-activated NK cells. (2007) (79)
Antigen recognition by human T cell receptor gamma-positive lymphocytes. Specific lysis of allogeneic cells after activation in mixed lymphocyte culture (1988) (79)
Familial Hemophagocytic Lymphohistiocytosis May Present during Adulthood: Clinical and Genetic Features of a Small Series (2012) (79)
Small round blue cell tumours: diagnostic and prognostic usefulness of the expression of B7-H3 surface molecule (2008) (79)
CD3+4−8−WT31− (T cell receptor γ+) cells and other unusual phenotypes are frequently detected among spontaneously interleukin 2‐responsive T lymphocytes present in the joint fluid in juvenile rheumatoid arthritis. A clonal analysis (1987) (79)
Identification of effector‐memory CMV‐specific T lymphocytes that kill CMV‐infected target cells in an HLA‐E‐restricted fashion (2005) (79)
Genotype–phenotype study of familial haemophagocytic lymphohistiocytosis type 3 (2011) (78)
Natural Killer Cells and Neuroblastoma: Tumor Recognition, Escape Mechanisms, and Possible Novel Immunotherapeutic Approaches (2014) (78)
The susceptibility to natural killer cell‐mediated lysis of HLA class I‐positive melanomas reflects the expression of insufficient amounts of different HLA class I alleles (1998) (77)
PD-L1 Assays 22C3 and SP263 are Not Interchangeable in Non–Small Cell Lung Cancer When Considering Clinically Relevant Cutoffs: An Interclone Evaluation by Differently Trained Pathologists (2018) (77)
Characterization of Human NK Cell-Derived Exosomes: Role of DNAM1 Receptor in Exosome-Mediated Cytotoxicity against Tumor (2020) (77)
Haemophagocytic lymphohistiocytosis: proposal of a diagnostic algorithm based on perforin expression (2002) (77)
NK cell activating receptors and tumor recognition in humans. (2006) (75)
Activating and inhibitory killer immunoglobulin‐like receptors (KIR) in haploidentical haemopoietic stem cell transplantation to cure high‐risk leukaemias (2009) (74)
The corticosteroid‐induced inhibitory effect on NK cell function reflects down‐regulation and/or dysfunction of triggering receptors involved in natural cytotoxicity (2004) (74)
Comparison of different CpG oligodeoxynucleotide classes for their capability to stimulate human NK cells (2006) (74)
Haploidentical hemopoietic stem cell transplantation for the treatment of high-risk leukemias: how NK cells make the difference. (2009) (72)
Markers and function of human NK cells in normal and pathological conditions (2017) (72)
A non-canonical adenosinergic pathway led by CD38 in human melanoma cells induces suppression of T cell proliferation (2015) (72)
Natural killer cells in HIV controller patients express an activated effector phenotype and do not up-regulate NKp44 on IL-2 stimulation (2013) (71)
IL‐12‐induced up‐regulation of NKRP1A expression in human NK cells and consequent NKRP1A‐ mediated down‐regulation of NK cell activation (1998) (71)
Identification, molecular cloning and functional characterization of NKp46 and NKp30 natural cytotoxicity receptors in Macaca fascicularis NK cells (2001) (71)
Membrane-bound and soluble IL-15/IL-15Ralpha complexes display differential signaling and functions on human hematopoietic progenitors. (2005) (71)
Monoclonal antibodies which react with the T cell receptor γ/δ recognize different subsets of CD3WT31‐ T lymphocytes (1989) (69)
Human CAR NK Cells: A New Non-viral Method Allowing High Efficient Transfection and Strong Tumor Cell Killing (2019) (69)
Antibody-induced modulation of the CD3/T cell receptor complex causes T cell refractoriness by inhibiting the early metabolic steps involved in T cell activation (1987) (69)
Group 3 innate lymphoid cells regulate neutrophil migration and function in human decidua (2016) (68)
Coexpression of two functionally independent p58 inhibitory receptors in human natural killer cell clones results in the inability to kill all normal allogeneic target cells. (1995) (68)
Histone deacetylase inhibitors sensitize tumour cells for cytotoxic effects of natural killer cells. (2008) (67)
PD-1 in human NK cells: evidence of cytoplasmic mRNA and protein expression (2018) (66)
Perturbations of natural killer cell regulatory functions in respiratory allergic diseases. (2008) (65)
Increased expression of the natural killer cell inhibitory receptor CD85j/ILT2 on antigen‐specific effector CD8 T cells and its impact on CD8 T‐cell function (2004) (65)
Identification and Molecular Characterization of NKp 30 , a Novel Triggering Receptor Involved in Natural Cytotoxicity Mediated by Human Natural Killer Cells (1999) (64)
Killer cell immunoglobulin-like receptor 3DL1 polymorphism defines distinct hierarchies of HLA class I recognition (2016) (64)
Human NK Cells: From Surface Receptors to the Therapy of Leukemias and Solid Tumors (2014) (64)
Assignment of human natural killer (NK)‐like cells to the T cell lineage. Single allospecific T cell clones lyse specific or NK‐sensitive target cells via distinct recognition structures (1984) (63)
Expression of HLA class I-specific inhibitory receptors in human cytolytic T lymphocytes: a regulated mechanism that controls T-cell activation and function. (2000) (63)
Both CD133+ and CD133– medulloblastoma cell lines express ligands for triggering NK receptors and are susceptible to NK‐mediated cytotoxicity (2007) (63)
Evidence that the KIR2DS5 gene codes for a surface receptor triggering natural killer cell function (2008) (61)
Analysis of the activating receptors and cytolytic function of human natural killer cells undergoing in vivo differentiation after allogeneic bone marrow transplantation (2004) (61)
Phenotypic diversity of natural killer (NK) populations in patients with NK-type lymphoproliferative disease of granular lymphocytes. (1993) (60)
Generation of CFU-C/suppressor T cells in vitro: an experimental model for immune-mediated marrow failure. (1981) (59)
Erratum: The natural killer cell-mediated killing of autologous dendritic cells in confined to a cell subset expressing CD94/NKG2A, but lacking inhibitory killer Ig-like receptors (European Journal of Immunology (2003) vol. 33 (6) (1657-1666)) (2003) (58)
Expression of CD94/NKG2A and killer immunoglobulin-like receptors in NK cells and a subset of extranodal cytotoxic T-cell lymphomas. (2000) (58)
NK-cell receptors and recognition of MHC class I molecules. (1996) (58)
Characterization of CD3+, CD4-, CD8- clones expressing the putative T cell receptor gamma gene product. Analysis of the activation pathways leading to interleukin 2 production and triggering of the lytic machinery (1987) (58)
Stromal Cells from Human Decidua Exert a Strong Inhibitory Effect on NK Cell Function and Dendritic Cell Differentiation (2014) (57)
Molecular definition of group 1 innate lymphoid cells in the mouse uterus (2018) (57)
Natural Killer Cells: A Mystery No More (2002) (57)
An Historical Overview: The Discovery of How NK Cells Can Kill Enemies, Recruit Defense Troops, and More (2019) (57)
Expression of human NKRP1A by CD34+ immature thymocytes: NKRP1A‐mediated regulation of proliferation and cytolytic activity (1996) (57)
Development of human natural killer cells and other innate lymphoid cells. (2014) (57)
Regulation of hematopoiesis in vitro by alloreactive natural killer cell clones (1993) (56)
CD56 Is a Pathogen Recognition Receptor on Human Natural Killer Cells (2017) (56)
Lymphokine production by T-cell clones after human bone marrow transplantation. (1989) (56)
Presence of innate lymphoid cells in pleural effusions of primary and metastatic tumors: Functional analysis and expression of PD‐1 receptor (2019) (55)
Spontaneous cell-mediated cytotoxicity in humans. Distribution and characterization of the effector cell. (1978) (55)
Human NK cells at early stages of differentiation produce CXCL8 and express CD161 molecule that functions as an activating receptor. (2012) (55)
The Immune Checkpoint PD-1 in Natural Killer Cells: Expression, Function and Targeting in Tumour Immunotherapy (2020) (54)
Surface antigens specifically expressed by activated T cells in humans (1981) (54)
Surface receptors delivering opposite signals regulate the function of human NK cells. (2000) (54)
NK Cell-Based Immunotherapy for Hematological Malignancies (2019) (54)
NK cells provide helper signal for CD8+ T cells by inducing the expression of membrane-bound IL-15 on DCs. (2009) (53)
Efficacy of third-party chimeric antigen receptor modified peripheral blood natural killer cells for adoptive cell therapy of B-cell precursor acute lymphoblastic leukemia (2019) (52)
The molecular bases of δ/αβ T cell–mediated antigen recognition (2014) (52)
Activated T lymphocytes in patients with multiple sclerosis (1983) (52)
Modulation of CD112 by the alphaherpesvirus gD protein suppresses DNAM-1–dependent NK cell-mediated lysis of infected cells (2014) (52)
Functionally relevant decreases in activatory receptor expression on NK cells are associated with pulmonary tuberculosis in vivo and persist after successful treatment. (2009) (52)
KIR and KIR ligand polymorphism: a new area for clinical applications? (2013) (51)
CD 16 surface molecules regulate the cytolytic function of CD3−CD16+ human natural killer cells (1989) (51)
Generation of a Novel Regulatory NK Cell Subset from Peripheral Blood CD34+ Progenitors Promoted by Membrane-Bound IL-15 (2008) (51)
Differential disappearance of inhibitory natural killer cell receptors during HAART and possible impairment of HIV-1-specific CD8 cytotoxic T lymphocytes (2001) (51)
Phenotypic characterization of human cytolytic T lymphocytes in mixed lymphocyte culture (1981) (50)
p40 molecule regulates NK cell activation mediated by NK receptors for HLA class I antigens and TCR-mediated triggering of T lymphocytes. (1997) (50)
Human CD8 T lymphocytes recognize Mycobacterium tuberculosis antigens presented by HLA‐E during active tuberculosis and express type 2 cytokines (2015) (50)
Engagement of CD33 surface molecules prevents the generation of dendritic cells from both monocytes and CD34+ myeloid precursors (2000) (50)
Human T cell receptor for IgM: specificity for the pentameric Fc fragment (1976) (49)
Innate Lymphoid Cells: Expression of PD-1 and Other Checkpoints in Normal and Pathological Conditions (2019) (49)
Recognition of adult and pediatric acute lymphoblastic leukemia blasts by natural killer cells (2014) (49)
Human natural killer cell function and their interactions with dendritic cells. (2003) (49)
HO-1 up-regulation: a key point in high-risk neuroblastoma resistance to bortezomib. (2014) (48)
Receptors for Immunoglobulins on Resting and Activated Human T Cells (1981) (48)
NK-cell Editing Mediates Epithelial-to-Mesenchymal Transition via Phenotypic and Proteomic Changes in Melanoma Cell Lines. (2018) (48)
CD3+ WT31− peripheral T lymphocytes lack T44 (CD28), a surface molecule involved in activation of T cells bearing the α/β heterodimer (1987) (48)
Natural Cytotoxicity of Human Fcγ‐Receptor‐positive T Lymphocytes after Surface Modulation with Immune Complexes (1979) (48)
HLA-E-restricted recognition of human cytomegalovirus by a subset of cytolytic T lymphocytes. (2004) (48)
p75/AIRM1 and CD33, two sialoadhesin receptors that regulate the proliferation or the survival of normal and leukemic myeloid cells (2001) (48)
Glucocorticoids and the cytokines IL-12, IL-15 and IL-18 present in the tumor microenvironment induce PD-1 expression on human Natural Killer cells. (2020) (47)
Dendritic cell editing by natural killer cells. (2014) (47)
Susceptibility of Human Melanoma Cells to Autologous Natural Killer (NK) Cell Killing: HLA-Related Effector Mechanisms and Role of Unlicensed NK Cells (2009) (47)
Human NK cell infusions prolong survival of metastatic human neuroblastoma-bearing NOD/scid mice (2007) (47)
Activating KIRs and NKG2C in Viral Infections: Toward NK Cell Memory? (2015) (47)
Fc-receptors for IgG and IgM immunoglobulins on human T lymphocytes: mode of re-expression after proteolysis or interaction with immune complexes. (1978) (47)
Expression and function of NKRP1A molecule on human monocytes and dendritic cells (1997) (46)
CD31‐triggered rearrangement of the actin cytoskeleton in human natural killer cells (1996) (46)
Nidogen-1 is a novel extracellular ligand for the NKp44 activating receptor (2018) (46)
Effect of human natural killer and gammadelta T cells on the growth of human autologous melanoma xenografts in SCID mice. (2004) (46)
HLA-E and HLA-E-bound peptides: recognition by subsets of NK and T cells. (2009) (46)
Expression of programmed cell death ligand 1 in non–small cell lung cancer: Comparison between cytologic smears, core biopsies, and whole sections using the SP263 assay (2018) (46)
The human natural killer cell receptor for major histocompatibility complex class I molecules. Surface modulation of p58 molecules and their linkage to CD3 ζ chain, FcϵRI γ chain and the p56lck kinase (1994) (45)
PD-1/PD-L1 in Cancer: Pathophysiological, Diagnostic and Therapeutic Aspects (2021) (45)
Control of self-reactive cytotoxic T lymphocytes expressing gamma delta T cell receptors by natural killer inhibitory receptors. (1997) (45)
Human Innate Lymphoid Cells: Their Functional and Cellular Interactions in Decidua (2018) (44)
Natural killer cell acceptance of H-2 mismatch bone marrow grafts in transgenic mice expressing HLA-Cw3 specific killer cell inhibitory receptor (CD158b) (1997) (44)
Human NK cells, their receptors and function (2021) (44)
HLA-G is a component of the chronic lymphocytic leukemia escape repertoire to generate immune suppression: impact of the HLA-G 14 base pair (rs66554220) polymorphism (2014) (44)
Heterogeneity of NK Cells and Other Innate Lymphoid Cells in Human and Murine Decidua (2019) (43)
In vivo generation of decidual natural killer cells from resident hematopoietic progenitors (2014) (43)
KIR2DS1-dependent acquisition of CCR7 and migratory properties by human NK cells interacting with allogeneic HLA-C2+ DCs or T-cell blasts. (2013) (43)
Zoledronic acid boosts γδ T-cell activity in children receiving αβ+ T and CD19+ cell-depleted grafts from an HLA-haplo-identical donor (2016) (43)
HLA-class I-specific inhibitory receptors in HIV-1 infection. (2000) (42)
Human natural killer cells and other innate lymphoid cells in cancer: Friends or foes? (2018) (42)
TLR-Stimulated Neutrophils Instruct NK Cells To Trigger Dendritic Cell Maturation and Promote Adaptive T Cell Responses (2015) (42)
Modulation of surface T11 molecules induced by monoclonal antibodies: analysis of the functional relationship between antigen‐dependent and antigen‐independent pathways of human T cell activation (1986) (42)
In vitro expansion of CD3/TCR- human thymocyte populations that selectively lack CD3 delta gene expression: a phenotypic and functional analysis (1990) (42)
Clonal analysis of CD4 CD8‐ human thymocytes expressing a T cell receptor γ/δ chain. Direct evidence for the de novo expression of CD8 surface antigen and of cytolytic activity against tumor targets* (1988) (41)
Development in vitro of human CD4+ thymocytes into functionally mature Th2 cells. Exogenous interleukin‐12 is required for priming thymocytes to produce both Th1 cytokines and interleukin‐10 (1996) (41)
Interactions between mesenchymal stem cells and dendritic cells. (2013) (41)
Association Between Response to Nivolumab Treatment and Peripheral Blood Lymphocyte Subsets in Patients With Non-small Cell Lung Cancer (2020) (41)
Analysis of the role of interferon‐gamma, interleukin 2 and a third factor distinct from interferon‐gamma and interleukin 2 on human B cell proliferation. Evidence that they act at different times after B cell activation (1986) (40)
4F2 monoclonal antibody recognizes a surface antigen on spread human fibroblasts of embryonic but not of adult origin (1984) (40)
Human natural killer cell activating receptors. (2000) (40)
NKp44-NKp44 Ligand Interactions in the Regulation of Natural Killer Cells and Other Innate Lymphoid Cells in Humans (2019) (40)
General role of HLA class I molecules in the protection of target cells from lysis by natural killer cells: evidence that the free heavy chains of class I molecules are not sufficient to mediate the protective effect. (1995) (40)
Inhibition of Human NK Cell-Mediated Killing by CD1 Molecules1 (2000) (40)
At the Bench: Preclinical rationale for exploiting NK cells and γδ T lymphocytes for the treatment of high‐risk leukemias (2013) (40)
NK cells from malignant pleural effusions are not anergic but produce cytokines and display strong antitumor activity on short‐term IL‐2 activation (2013) (40)
Familial hemophagocytic lymphohistiocytosis: a model for understanding the human machinery of cellular cytotoxicity (2011) (40)
New miRNA Signature Heralds Human NK Cell Subsets at Different Maturation Steps: Involvement of miR-146a-5p in the Regulation of KIR Expression (2018) (40)
Boosting Natural Killer Cell-Based Immunotherapy with Anticancer Drugs: a Perspective. (2017) (39)
Human cytolytic cell clones lacking surface expression of T cell receptor alpha/beta or gamma/delta. Evidence that surface structures other than CD3 or CD2 molecules are required for signal transduction (1988) (39)
Natural killer cells in human pregnancy. (2013) (39)
Phenotypic and functional analysis of CD4+ NKRP1A+ human T lymphocytes. Direct evidence that the NKRP1A molecule is involved in transendothelial migration. (1997) (39)
Human γδ T-Cells: From Surface Receptors to the Therapy of High-Risk Leukemias (2018) (39)
Human cytolytic T lymphocytes expressing HLA class-I-specific inhibitory receptors. (2005) (38)
CD45‐mediated regulation of LFA1 function in human natural killer cells. Anti‐CD45 monoclonal antibodies inhibit the calcium mobilization induced via LFA1 molecules (1993) (38)
X-Linked Lymphoproliferative Disease (2000) (38)
PD-1 is expressed by and regulates human group 3 innate lymphoid cells in human decidua (2019) (38)
Role of Nrf2, HO-1 and GSH in Neuroblastoma Cell Resistance to Bortezomib (2016) (38)
Human T cell subpopulations defined by a monoclonal antibody. II. Evidence for cell cooperation in the response to alloantigens and generation of cytolytic cells. (1982) (38)
Frequent coexpression of cytolytic activity and lymphokine production among human T lymphocytes. Production of B cell growth factor and interleukin 2 by T8+ and T4+ cytolytic clones (1984) (37)
Inhibitory Receptors and Checkpoints in Human NK Cells, Implications for the Immunotherapy of Cancer (2020) (37)
Ultrastructural characteristics of human T cell clones with various cytolytic activities (1983) (37)
Human natural killer cells: news in the therapy of solid tumors and high-risk leukemias (2016) (37)
NK Cells and Other Innate Lymphoid Cells in Hematopoietic Stem Cell Transplantation (2016) (37)
Bispecific monoclonal antibodies directed to CD16 and to a tumor‐associated antigen induce target‐cell lysis by resting NK cells and by a subset of NK clones (1991) (37)
The analysis of the natural killer-like activity of human cytolytic T lymphocytes revealed HLA-E as a novel target for TCR alpha/beta-mediated recognition. (2001) (37)
Human NK Cell Subsets Redistribution in Pathological Conditions: A Role for CCR7 Receptor (2016) (37)
Immune Checkpoint Inhibitors: Anti-NKG2A Antibodies on Board. (2019) (36)
Human NK receptors: From the molecules to the therapy of high risk leukemias (2011) (36)
Methylprednisolone induces preferential and rapid differentiation of CD34+ cord blood precursors toward NK cells. (2008) (36)
The generation of human innate lymphoid cells is influenced by the source of hematopoietic stem cells and by the use of G‐CSF (2016) (35)
Engagement of the leukocyte‐associated Ig‐like receptor‐1 induces programmed cell death and prevents NF‐κB nuclear translocation in human myeloid leukemias (2000) (35)
Phenotypic and functional analysis of CD4+ NKRP1A+ human T lymphocytes. Direct evidence that the NKRP1A molecule is involved in transendothelial migration (1997) (35)
Human NK cells: From surface receptors to clinical applications. (2016) (35)
Specificity of human T lymphocytes expressing a γ/δ T cell antigen receptor. Recognition of a polymorphic determinant of HLA class I molecules by a γ/δ clone (1989) (34)
Functional characterization of natural killer cells in type I leukocyte adhesion deficiency. (2007) (34)
Proliferation of T8-positive cytolytic T lymphocytes in response to thyroglobulin in human autoimmune thyroiditis: analysis of cell interactions and culture requirements. (1985) (33)
Human innate lymphoid cells. (2016) (33)
Structure of the human NK cell triggering receptor NKp46 ectodomain. (2003) (33)
Isolation and in vitro expansion of lymphocytes infiltrating non-small cell lung carcinoma: functional and molecular characterisation for their use in adoptive immunotherapy. (1994) (33)
Clonal analysis and in situ characterization of lymphocytes infiltrating human breast carcinomas (2004) (33)
The natural killer-related receptor for HLA-C expressed on T cells from CD3+ lymphoproliferative disease of granular lymphocytes displays either inhibitory or stimulatory function. (1996) (33)
The yin‐yang of the interaction between myelomonocytic cells and NK cells (2018) (33)
Molecular and Functional Characterization of NKG2D, NKp80, and NKG2C Triggering NK Cell Receptors in Rhesus and Cynomolgus Macaques: Monitoring of NK Cell Function during Simian HIV Infection1 (2005) (32)
Fc Receptors on Human T Lymphocytes: Loss of Fcμ and Expression of Fcγ Receptors by T Cells Stimulated in Mixed Lymphocyte Reaction (1981) (32)
Human Congenital Infection With Trypanosoma cruzi Induces Phenotypic and Functional Modifications of Cord Blood NK Cells (2006) (32)
Gntb-A, a Novel Sh2d1a-Associated Surface Molecule Contributing to the Inability of Natural Killer Cells to Kill Epstein-Barr Virus–Infected B Cells in X-Linked Lymphoproliferative Disease (2001) (31)
Heterogeneity of TLR3 mRNA transcripts and responsiveness to poly (I:C) in human NK cells derived from different donors. (2007) (31)
Human NK Cells and Herpesviruses: Mechanisms of Recognition, Response and Adaptation (2019) (31)
Mobilization of healthy donors with plerixafor affects the cellular composition of T-cell receptor (TCR)-αβ/CD19-depleted haploidentical stem cell grafts (2014) (31)
CD28.OX40 co-stimulatory combination is associated with long in vivo persistence and high activity of CAR.CD30 T cells (2020) (31)
MYCN is an immunosuppressive oncogene dampening the expression of ligands for NK-cell-activating receptors in human high-risk neuroblastoma (2017) (30)
Successfully treated HIV-infected patients have differential expression of NK cell receptors (NKp46 and NKp30) according to AIDS status at presentation. (2013) (30)
Human CD3+4−8−WT31−T lymphocyte expressing the putative T cell receptor γ‐gene product. A limiting dilution and clonal analysis (1987) (30)
Cellular and molecular basis of natural killer and natural killer-like activity. (2003) (30)
Late Development of FcεRγneg Adaptive Natural Killer Cells Upon Human Cytomegalovirus Reactivation in Umbilical Cord Blood Transplantation Recipients (2018) (30)
Combined Genotypic and Phenotypic Killer Cell Ig-Like Receptor Analyses Reveal KIR2DL3 Alleles Displaying Unexpected Monoclonal Antibody Reactivity: Identification of the Amino Acid Residues Critical for Staining (2010) (30)
Exploiting Human NK Cells in Tumor Therapy (2020) (30)
A novel 120-kD surface antigen expressed by a subset of human lymphocytes. Evidence that lymphokine-activated killer cells express this molecule and use it in their effector function (1987) (30)
Origin and functions of human natural killer cells (1994) (30)
The LFA‐1/ICAM cell adhesion pathway is involved in tumor‐cell lysis mediated by bispecific monoclonal‐antibody‐targeted T lymphocytes (1994) (30)
Control of the HIV-1 DNA Reservoir Is Associated In Vivo and In Vitro with NKp46/NKp30 (CD335 CD337) Inducibility and Interferon Gamma Production by Transcriptionally Unique NK Cells (2017) (30)
B cell growth factor activity of immunoaffinity‐purified and recombinant human interleukin 2 (1985) (29)
Interleukin-15 and cancer: some solved and many unsolved questions (2020) (29)
Receptors for IgM are expressed on acute lymphoblastic leukemic cells having T-cell characteristics. (1977) (28)
CD8+ cytolytic T lymphocytes become infected in vitro in the process of killing HIV‐1‐infected target cells (1994) (28)
Human lymphocyte surface markers. (1982) (28)
Extending killer Ig-like receptor function: from HLA class I recognition to sensors of microbial products. (2010) (28)
Phenotypic and functional analysis of the HLA-class I-specific inhibitory receptors of natural killer cells isolated from peripheral blood of patients undergoing bone marrow transplantation from matched unrelated donors. (2000) (28)
NKRP1A molecule is involved in transendothelial migration of CD4+ human T lymphocytes. (1997) (27)
Natural Killer (NK)/melanoma cell interaction induces NK-mediated release of chemotactic High Mobility Group Box-1 (HMGB1) capable of amplifying NK cell recruitment (2015) (27)
Human T‐Lymphocyte Subpopulations: Alterations in Systemic Lupus Erythematosus (1979) (27)
Polymorphonuclear myeloid-derived suppressor cells impair the anti-tumor efficacy of GD2.CAR T-cells in patients with neuroblastoma (2021) (27)
Regulation of IgG Antibody‐dependent Cellular Cytotoxicity in Vitro by IgM Antibodies (1981) (27)
Surface markers of cloned human T cells with helper or suppressor activity on pokeweed mitogen‐driven B cell differentiation (1982) (27)
NKp44 expression, phylogenesis and function in non-human primate NK cells. (2009) (27)
Human CD3−CD16+ natural killer cells express the hGATA‐3 T cell transcription factor and an unrearranged 2.3‐kb TcR δ transcript (1993) (27)
Subpopulations of human T lymphocytes. (1980) (26)
Structure of the Ly49 family of natural killer (NK) cell receptors and their interaction with MHC class I molecules (2004) (26)
Selective increase of a subset of T cell receptor gamma delta T lymphocytes in the peripheral blood of patients with human immunodeficiency virus type 1 infection. (1992) (26)
P377 - The HLA-C-specific “activatory” or “inhibitory” natural killer cell receptors display highly homologous extracellular domains but differ in their transmembrane and intracytoplasmic portions (1996) (26)
Functional characterization of human thymocytes: a limiting dilution analysis of precursors with proliferative and cytolytic activities. (1985) (26)
ANALYSIS OF NATURAL KILLER CELLS ISOLATED FROM HUMAN DECIDUA : EVIDENCE THAT 2 B 4 ( CD 244 ) FUNCTIONS AS AN INHIBITORY RECEPTOR AND BLOCKS NK CELL FUNCTION Running title : dNK cells and 2 B 4 function (2006) (26)
Organization and orientation of a human T cell receptor δ chain V gene segment that suggests an inversion mechanism is utilized in its rearrangement (1989) (26)
PD-L1 expression comparison between primary and relapsed non-small cell lung carcinoma using whole sections and clone SP263 (2018) (26)
Signal transducing mechanisms involved in human T cell activation via surface T44 molecules. Comparison with signals transduced via the T cell receptor complex (1986) (26)
Selection and characterization of monoclonal antibodies to the idiotype‐like structure of an interleukin‐2‐producing human leukemia t‐cell line (1985) (26)
How melanoma cells inactivate NK cells (2012) (25)
Treatment of stage IIIB non-small-cell lung cancer with surgery followed by infusion of tumor infiltrating lymphocytes and recombinant interleukin-2: a pilot study. (1996) (25)
T cell nature of some lymphokine‐activated killer (LAK) cells. Frequency analysis of LAK precursors within human T cell populations and clonal analysis of LAK effector cells (1986) (25)
The molecular basis of Natural Killer (NK) cell recognition and function (1996) (25)
MSC and innate immune cell interactions: A lesson from human decidua. (2015) (25)
Natural killer cell-mediated recognition of human trophoblast. (1999) (24)
Peptides with dual binding specificity for HLA-A2 and HLA-E are encoded by alternatively spliced isoforms of the antioxidant enzyme peroxiredoxin 5. (2009) (24)
Natural killer cell acceptance of H-2 mismatch bone marrow grafts in transgenic mice expressing HLA-Cw3 specific killer cell inhibitory receptor. (1997) (24)
Dissection of lymphocyte function‐associated antigen 1‐dependent adhesion and signal transduction in human natural killer cells shown by the use of cholera or pertussis toxin (1996) (24)
PMN-MDSC are a new target to rescue graft-versus-leukemia activity of NK cells in haplo-HSC transplantation (2019) (24)
Human natural killer (NK) alloreactivity and its association with the major histocompatibility complex: ancestral haplotypes encode particular NK-defined haplotypes (1993) (24)
Clonal analysis of T lymphocytes in spleens from patients with Hodgkin's disease. Frequent occurrence of unusual T4‐positive cells which co‐express cytolytic activity and production of interleukin‐2 (1986) (24)
Re‐targeting of human lymphocytes expressing the T‐cell receptor gamma/delta to ovarian carcinoma cells by the use of bispecific monoclonal antibodies (1989) (23)
The Innate Immune Cross Talk between NK Cells and Eosinophils Is Regulated by the Interaction of Natural Cytotoxicity Receptors with Eosinophil Surface Ligands (2017) (23)
The molecular bases of delta/alpha beta T cell-mediated antigen recognition (2014) (23)
Human T-lymphocyte subpopulations in Hashimoto's disease. (1981) (23)
P49, a putative HLA-G1 specific inhibitory NK receptor belonging to the immunoglobulin Superfamily. (1999) (23)
XLP1 inhibitory effect by 2B4 does not affect DNAM‐1 and NKG2D activating pathways in NK cells (2014) (22)
Human natural killer cells undergoing in vivo differentiation after allogeneic bone marrow transplantation: analysis of the surface expression and function of activating NK receptors. (2005) (22)
Analysis of the expression of the 4F2 surface antigen in normal and neoplastic fibroblastic human cells of embryonic and adult origin. (1985) (22)
Cytolytic function of clonable T cells after human bone marrow transplantation. (1990) (22)
Specificity of human T lymphocytes expressing a gamma/delta T cell antigen receptor. Recognition of a polymorphic determinant of HLA class I molecules by a gamma/delta clone. (1989) (22)
Tγδ Cell Subsets in Cord and Adult Blood (1990) (22)
PD-L1 expression in non-small cell lung cancer: evaluation of the diagnostic accuracy of a laboratory developed test using clone E1L3N in comparison with 22C3 and SP263 assays. (2019) (22)
Interaction Between MDSC and NK Cells in Solid and Hematological Malignancies: Impact on HSCT (2021) (22)
IL‐1β inhibits ILC3 while favoring NK‐cell maturation of umbilical cord blood CD34+ precursors (2015) (21)
Phenotypic and functional analysis of human CD3 + and CD3− clones with “lymphokine‐activated killer” (LAK) activity. Frequent occurrence of CD3 + LAK clones which produce interleukin‐2 (1987) (21)
Pseudorabies Virus US3 Protein Kinase Protects Infected Cells from NK Cell-Mediated Lysis via Increased Binding of the Inhibitory NK Cell Receptor CD300a (2015) (21)
‘Emergency exit' of bone-marrow-resident CD34+DNAM-1brightCXCR4+-committed lymphoid precursors during chronic infection and inflammation (2015) (21)
CD8+ NK cells are predominant in chimpanzees, characterized by high NCR expression and cytokine production, and preserved in chronic HIV‐1 infection (2010) (21)
Ontogeny, specific functions and receptors of human natural killer cells. (1994) (21)
Differential NKp30 Inducibility in Chimpanzee NK Cells and Conserved NK Cell Phenotype and Function in Long-Term HIV-1-Infected Animals1 (2007) (21)
NK cell-mediated immune response against cancer. (2007) (21)
Surface markers of human lymphokine‐activated killer cells and their precursors. Analysis at the population and clonal level (1987) (20)
Specific removal of alloreactive T-cells to prevent GvHD in hemopoietic stem cell transplantation: rationale, strategies and perspectives. (2016) (20)
Sub-lingual administration of a polyvalent mechanical bacterial lysate (PMBL) in patients with moderate, severe, or very severe chronic obstructive pulmonary disease (COPD) according to the GOLD spirometric classification: A multicentre, double-blind, randomised, controlled, phase IV study (AIACE st (2015) (20)
Targeting of T or NK lymphocytes against tumor cells by bispecific monoclonal antibodies: role of different triggering molecules. (1992) (20)
Strategies to optimize the outcome of children given T-cell depleted HLA-haploidentical hematopoietic stem cell transplantation. (2011) (20)
Interleukin-2 mediated restoration of natural killer cell function in a patient with Griscelli syndrome (2000) (20)
Structure of the saccharide-binding domain of the human natural killer cell inhibitory receptor p75/AIRM1. (2004) (20)
Anticlonotypic monoclonal antibodies induce proliferation of clonotype- positive T cells in peripheral blood human T lymphocytes. Evidence for a phenotypic (T4/T8) heterogeneity of the clonotype-positive proliferating cells (1985) (19)
Low expression of inhibitory natural killer receptors in CD8 cytotoxic T lymphocytes in long-term non-progressor HIV-1-infected patients. (2003) (19)
CD16 surface molecules regulate the cytolytic function of CD3CD16+ human natural killer cells. (1989) (19)
Inhibitory 2B4 contributes to NK cell education and immunological derangements in XLP1 patients (2017) (19)
Role of Ia antigens in the human autologous mixed lymphocyte reaction (1982) (19)
Targeting of T lymphocytes against egf‐receptor+ tumor cells by bispecific monoclonal antibodies: Requirement of CD3 molecule cross‐linking for t‐cell activation (1993) (19)
Increased expression of non‐functional killer inhibitory receptor CD94 in CD8+ cells of myeloma patients (2000) (18)
Differential NKp30 inducibility in chimpanzee NK cells and conserved NK cell phenotype and function in long-term HIV-1-infected animals (2007) (18)
Update of CD antigens, 1996. (1997) (18)
Different Features of Tumor-Associated NK Cells in Patients With Low-Grade or High-Grade Peritoneal Carcinomatosis (2019) (18)
gd T-cell reconstitution after HLA-haploidentical hematopoietic transplantation depleted of TCR- ab 1 /CD19 1 lymphocytes (2016) (18)
A conserved energetic footprint underpins recognition of human leukocyte antigen-E by two distinct αβ T cell receptors (2017) (18)
Stimulatory receptors in NK and T cells. (1998) (18)
Comparative analysis of NK‐ or NK‐CTL‐mediated lysis of immature or mature autologous dendritic cells (2003) (18)
Immunobiology of human NK cells. (2001) (17)
Cytokine-induced expression of killer inhibitory receptors in human T lymphocytes. (1998) (17)
Human T lymphocytes expressing gamma/delta T cell antigen receptor. (1989) (17)
Molecular classification of mature aggressive B-cell lymphoma using digital multiplexed gene expression on formalin-fixed paraffin-embedded biopsy specimens (2017) (17)
Natural killer alloeffector responses in haploidentical hemopoietic stem cell transplantation to treat high-risk leukemias. (2010) (17)
Involvement of T11 molecules in antigen receptormediated T lymphocyte functions: effect of anti‐T11 monoclonal antibody on functional capabilities of alloreactive T cell clones (1985) (17)
Comprehensive Phenotyping of Human PB NK Cells by Flow Cytometry (2020) (17)
Cloning and proliferating precursor frequencies of tumor-infiltrating lymphocytes from human solid tumors. (1988) (17)
HCMV-controlling NKG2C+ NK cells originate from novel circulating inflammatory precursors. (2021) (17)
Identification and molecular characterization of a natural mutant of the p50.2/KIR2DS2 activating NK receptor that fails to mediate NK cell triggering (2000) (16)
Hematopoietic stem cell transplantation: Improving alloreactive Bw4 donor selection by genotyping codon 86 of KIR3DL1/S1 (2016) (16)
P373 - The natural killer cell receptor specific for HLA-A allotypes: A novel member of the p58/p70 family of inhibitory receptors which is characterized by three Ig-like domains and is expressed as a 140 kD disulphide-linked dimer (1996) (16)
Erratum: Selective increase of a subset of T cell receptor γδT lymphocytes in the peripheral blood of patients with human immunodeficiency virus type 1 infection (J Infect Dis (1992) 165 (917-919)) (1992) (16)
Analysis of NK cell/DC interaction in NK-type lymphoproliferative disease of granular lymphocytes (LDGL): role of DNAM-1 and NKp30. (2009) (15)
Analysis of signal transducing mechanisms in CD3+ CD4- CD8- cells expressing the putative T cell receptor gamma gene product. (1987) (15)
Monoclonal antibodies which react with the T cell receptor gamma/delta recognize different subsets of CD3+WT31- T lymphocytes. (1989) (15)
Frequent T4-positive cells with cytolytic activity in spleens of patients with Hodgkin's disease (a clonal analysis). (1986) (15)
Diagnosing XLP1 in patients with hemophagocytic lymphohistiocytosis. (2014) (15)
Melanoma immunoediting by NK cells (2012) (15)
Phenotypic and functional characteristics of tumor‐associated lymphocytes in patients with malignant ascites receiving intraperitoneal infusions of recombinant interleukin‐2 (ril‐2) (1989) (14)
Faculty Opinions recommendation of PD-1 blockade for relapsed lymphoma post-allogeneic hematopoietic cell transplant: high response rate but frequent GVHD. (2017) (14)
HO‐1 downregulation favors BRAFV600 melanoma cell death induced by Vemurafenib/PLX4032 and increases NK recognition (2020) (14)
Characterisation of innate lymphoid cell subsets infiltrating colorectal carcinoma (2020) (14)
IL15 induces a potent antitumor activity in NK cells isolated from malignant pleural effusions and overcomes the inhibitory effect of pleural fluid (2017) (14)
Impact of PD-L1 and PD-1 Expression on the Prognostic Significance of CD8+ Tumor-Infiltrating Lymphocytes in Non-Small Cell Lung Cancer (2021) (14)
Nutlin-3a Enhances Natural Killer Cell–Mediated Killing of Neuroblastoma by Restoring p53-Dependent Expression of Ligands for NKG2D and DNAM-1 Receptors (2020) (14)
Surface receptors that regulate the NK cell function: beyond the NK cell scope. (2002) (14)
IL-1β-releasing human acute myeloid leukemia blasts modulate natural killer cell differentiation from CD34+ precursors (2015) (14)
PD-L1 evaluation in head and neck squamous cell carcinoma: Insights regarding specimens, heterogeneity and therapy. (2021) (14)
Pathogenic Mechanisms of Vaccine-Induced Immune Thrombotic Thrombocytopenia in People Receiving Anti-COVID-19 Adenoviral-Based Vaccines: A Proposal (2021) (14)
TGFβ1 inhibits the surface expression of the NKp30 and NKG2D triggering NK receptors: consequences for the NK-mediated killing of dendritic cells (2003) (14)
Metformin exerts anti-cancerogenic effects and reverses epithelial-to-mesenchymal transition trait in primary human intrahepatic cholangiocarcinoma cells (2021) (14)
Imbalance of T-cell subpopulations and defective pokeweed mitogen-induced B-cell differentiation after bone marrow transplantation in man. (1981) (13)
Polymorphonuclear Myeloid-Derived Suppressor Cells Are Abundant in Peripheral Blood of Cancer Patients and Suppress Natural Killer Cell Anti-Tumor Activity (2022) (13)
Human natural killer cells in pregnancy (2012) (13)
NK cells from malignant pleural effusions are potent antitumor effectors (2013) (13)
Perilymphatic injections of recombinant interleukin‐2 (rIL‐2) partially correct the immunologic defects in patients with advanced head and neck squamous cell carcinoma (1992) (13)
Transplantation of TcRαβ/CD19 Depleted Stem Cells From Haploidentical Donors: Robust Engraftment and Rapid Immune Reconstitution In Children with High Risk Leukemia (2011) (13)
Cytokines can counteract the inhibitory effect of MEK-i on NK-cell function (2016) (13)
Cancer Immunotherapy Principles and Practice (2018) (13)
Surface receptors and functional interactions of human natural killer cells: from bench to the clinic (2003) (13)
CD3+ WT31- peripheral T lymphocytes lack T44 (CD28), a surface molecule involved in activation of T cells bearing the alpha/beta heterodimer. (1987) (13)
Natural Killer‐like Cytotoxicity of Human T‐Cell Clones against Various Target Cells (1983) (13)
Use of anti-CD3 and anti-CD16 bispecific monoclonal antibodies for the targeting of T and NK cells against tumor cells. (1993) (13)
Haploidentical Haematopoietic Stem Cell Transplantation: Role of NK Cells and Effect of Cytomegalovirus Infections. (2016) (13)
Selective Preservation of Bone Marrow Mature Recirculating but Not Marginal Zone B Cells in Murine Models of Chronic Inflammation (2010) (13)
Major Histocompatibility Complex Class I-related Chain A and UL 16-Binding Protein Expression on Tumor Cell Lines of Different Histotypes : Analysis of Tumor Susceptibility to NKG 2 D-dependent Natural Killer Cell Cytotoxicity 1 (2002) (12)
Human NK cells: surface receptors, inhibitory checkpoints, and translational applications (2019) (12)
Comparison of the colony-forming capacities of human T-lymphocyte subpopulations. (1981) (12)
IFN‐α‐mediated increase in cytolytic activity of maturing NK cell upon exposure to HSV‐infected myelomonocytes (2009) (12)
Cyclosporin-A inhibits IL-2 production by all human T-cell clones having this function, independent of the T4/T8 phenotype or the coexpression of cytolytic activity. (1986) (12)
Erratum: Natural killer cells in HIV-1 infection: Dichotomous effects of viremia on inhibitory and activating receptors and their functional correlates (Proceedings of the National Academy of Sciences of the United States of America (December 9, 2003) 100, 25 (15011-15016)) (2004) (11)
Human CD3+4-8-WT31- T lymphocyte populations expressing the putative T cell receptor gamma-gene product. A limiting dilution and clonal analysis. (1987) (11)
Immunotherapy and immunity to cancer: cellular mechanisms. (1989) (11)
ANTIGEN RECOGNITION BY HUMAN T CELL RECEPTOR y-POSITIVE LYMPHOCYTES Specific Lysis of Allogeneic Mixed Lymphocyte Culture BriefDefinitiveReport (1988) (11)
An Anti-inflammatory microRNA Signature Distinguishes Group 3 Innate Lymphoid Cells From Natural Killer Cells in Human Decidua (2020) (11)
Entropically Assisted Carbohydrate Recognition by a Natural Killer Cell‐Surface Receptor (2004) (11)
Human natural killer cells: clonally distributed specific functions and triggering surface molecules. (1992) (11)
Revisited function of human NK cell subsets (2011) (11)
TSC loss is a clonal event in eosinophilic solid and cystic renal cell carcinoma: a multiregional tumor sampling study (2021) (11)
NK cell function in HIV-1 infection. (2008) (11)
Innate lymphoid cells in normal and disease: An introductory overview. (2016) (11)
Lymphocyte effector mechanisms in innate and adaptive immunity. (2005) (11)
KIR Variation in Iranians Combines High Haplotype and Allotype Diversity With an Abundance of Functional Inhibitory Receptors (2020) (11)
Phenotypic and Functional Characterization of NK Cells in αβT-Cell and B-Cell Depleted Haplo-HSCT to Cure Pediatric Patients with Acute Leukemia (2020) (11)
Inhibitory checkpoints in human natural killer cells: IUPHAR Review 28 (2020) (11)
NK-cell phenotype at interruption underlies widely divergent duration of CD4+-guided antiretroviral treatment interruption. (2011) (11)
On the pathogenesis of perforin defects and related immunodeficiencies. (2000) (10)
Group 2 Innate Lymphoid Cells: A Double-Edged Sword in Cancer? (2020) (10)
Suppressor Activity of T Cells Bearing Fc Receptors for IgG on Lymphoid Colony Formation (1980) (10)
Effect of Tyrosin Kinase Inhibitors on NK Cell and ILC3 Development and Function (2018) (10)
Characterization of Human Afferent Lymph Dendritic Cells from Seroma Fluids (2013) (10)
Peripheral Blood Mononuclear Cell Immunophenotyping in Fibrodysplasia Ossificans Progressiva Patients: Evidence for Monocyte DNAM1 Up‐regulation (2018) (10)
Human NK cells (2015) (9)
Retargeting of T‐cell‐receptor gamma/delta+ lymphocytes against tumor cells by bispecific monoclonal antibodies. Induction of cytolytic activity and lymphokine production (1989) (9)
Regulation of the Immune System Development by Glucocorticoids and Sex Hormones (2021) (9)
Identification of neuroblastoma cell lines with uncommon TAZ+/mesenchymal stromal cell phenotype with strong suppressive activity on natural killer cells (2021) (9)
Purification and HPLC-MS analysis of a naturally processed HCMV-derived peptide isolated from the HEK-293T/HLA-E+/Ul40+ cell transfectants and presented at the cell surface in the context of HLA-E. (2007) (9)
Specific recognition by CD3− NK cells: A limiting dilution analysis of the frequency of alloreactive CD3− lymphocyte precursors (1989) (9)
Mesenchymal stromal cells and immunity: Introductory overview. (2015) (9)
Natural killer cell receptors regulate responses of HLA-E–restricted T cells (2021) (9)
Clonal analysis of joint fluid T lymphocytes in patients with juvenile rheumatoid arthritis. (1990) (9)
Existence of a natural killer (NK) cell repertoire for (allo)antigen recognition: definition of five distinct NK-determined allospecificities in humans. (1992) (8)
Inhibitory receptors for HLA class I molecules on cytolytic T lymphocytes (1997) (8)
MULTIPLE RELAPSES OF VISCERAL LEISHMANIASIS IN AN ADOLESCENT WITH IDIOPATHIC CD4+ LYMPHOCYTOPENIA ASSOCIATED WITH NOVEL IMMUNOPHENOTYPIC AND MOLECULAR FEATURES (2009) (8)
TRANSPLANTATION Outcome of children with acute leukemia given HLA-haploidentical HSCT after ab T-cell and B-cell depletion (2017) (8)
Identification and Molecular Cloning of p 75 / AIRM 1 , A Novel Member of the Sialoadhesin Family That Functions as an Inhibitory Receptor in Human Natural Killer Cells (1999) (8)
Inherent transcriptional signatures of NK cells are associated with response to IFNα + rivabirin therapy in patients with Hepatitis C Virus (2015) (8)
Helper Innate Lymphoid Cells in Human Tumors: A Double-Edged Sword? (2020) (8)
Distribution and properties of Fc receptors for IgG on different leucocyte populations in man. (1981) (8)
Crystallization and preliminary crystallographic characterization of the extracellular Ig-like domain of human natural killer cell activating receptor NKp44. (2002) (8)
Expression, crystallization and preliminary crystallographic analysis of the extracellular IgV-like domain of the human natural killer cell inhibitory receptor p75/AIRM1. (2003) (7)
Activation NK Cells upondimAcquire Features of CD 56 NK Cells Display Longer Telomeres and − Killer Ig-Like Receptor − CD 16 brightCD 56 (2007) (7)
Possible targets on carcinoma for bMAb retargeting of lymphocyte or drug cytotoxicity. (1992) (7)
Wilms’ Tumor Primary Cells Display Potent Immunoregulatory Properties on NK Cells and Macrophages (2021) (7)
Human T cells expressing the y/6 T-cell receptor (TcR-1): Ci,-and CY2-encoded forms of the receptor correlate with distinctive morphology, cytoskeletal organization, and growth characteristics (7)
Surface markers of human T lymphocytes (1982) (7)
The C gamma 1-encoded disulphide-linked and the C gamma 2-encoded nondisulphide-linked forms of the gamma/delta heterodimer use different gamma and delta variable regions [see comments] (1990) (7)
Transplantation and innate immunity: the lesson of natural killer cells (2009) (7)
Cellular and molecular pathogenesis of X-linked lymphoproliferative disease (2001) (7)
Toll-like receptor 8 agonists improve NK-cell function primarily targeting CD56brightCD16− subset (2022) (7)
Mesenchymal Stem Cell-Natural Killer Cell Interactions (2012) (7)
NK Cells and PMN-MDSCs in the Graft From G-CSF Mobilized Haploidentical Donors Display Distinct Gene Expression Profiles From Those of the Non-Mobilized Counterpart (2021) (7)
Receptors for immunoglobulins and activation markers on human T lymphocytes. (1982) (6)
Phenotypic and functional heterogeneity of human peripheral blood T lymphocytes producing colony stimulating factor. A clonal and precursor frequency analysis. (1985) (6)
Technical and Diagnostic Issues in Whole Slide Imaging Published Validation Studies (2022) (6)
Natural killer cells in pregnancy: How do they avoid attacking fetal tissues? (1999) (6)
Pediatric Tumors-Mediated Inhibitory Effect on NK Cells: The Case of Neuroblastoma and Wilms’ Tumors (2021) (6)
HLA Haploidentical Stem Cell Transplantation After Removal of αβ + T Lymphocytes and B Lymphocytes Is an Effective Treatment for Children with Life-Threatening, Non-Malignant Disorders (2012) (6)
Expression of a wide T cell receptor Vβ repertoire in human T lymphocytes derived in vitro from embryonic liver cell precursors (1994) (6)
Alloreactive natural killer cells in targeting high-risk leukaemias (2008) (6)
KIR B haplotype donors confer a reduced risk of relapse after haploidentical transplantation in children with acute lymphoblastic leukemia (2014) (6)
A pathogenic integrated view explaining the different endotypes of asthma and allergic disorders (2022) (6)
Natural killer cells carry the germ‐line configuration of the T cell receptor δ chain gene and heterogeneously express six distinct δ transcripts (1990) (6)
CD19 Redirected CAR NK Cells Are Equally Effective but Less Toxic Than CAR T Cells (2018) (6)
Phenotypic and functional heterogeneity of human T lymphocytes producing B-cell growth factor(s): a clonal analysis. (1985) (6)
Natural killer cells: From surface receptors to the cure of high‐risk leukemia (Ceppellini Lecture) (2019) (6)
Increasing LFA-1 Expression Enhances Immune Synapse Architecture and T Cell Receptor Signaling in Jurkat E6.1 Cells (2021) (6)
Expression and crystallographic characterization of the extracellular domain of human natural killer cell triggering receptor NKp46. (2003) (6)
A Novel surface molecule expressed by long‐term cultured T and natural killer cells is involved in cell activation (1991) (6)
Molecular heterogeneity of the 1.0‐kb Tβ transcript in natural killer and γ/δ lymphocytes (1991) (6)
Analysis of memory-like Natural Killer cells in Human Cytomegalovirus-infected children undergoing + T-and B-cell depleted HSCT for hematological malignancies (2015) (5)
Removal Of Alpha/Beta+ T Cells and Of CD19+ B Cells From The Graft Translates Into Rapid Engraftment, Absence Of Visceral Graft-Versus-Host Disease and Low Transplant-Related Mortality In Children With Acute Leukemia Given HLA-Haploidentical Hematopoietic Stem Cell Transplantation (2013) (5)
Phenotypic and functional properties of mouse and human thymocytes. (1984) (5)
p49, a putative HLA classs I‐specific inhibitory NK receptor belonging to the immunoglobulin super‐family (Vol 28(6) 1998, pp 1980‐1990) (1998) (5)
This information is current as Cells Expressed and Functional on Human Mast The Inhibitory Receptor IRp 60 ( CD 300 a ) Is Moretta and (2005) (5)
Interleukin 2 and interferon‐γ are not sufficient to induce natural killer‐like activity in human T cell clones (1984) (5)
Update: new CD antigens, 1996. (1997) (5)
Analysis of KIR3DP1 Polymorphism Provides Relevant Information on Centromeric KIR Gene Content (2018) (5)
Understanding human NK cell differentiation: clues for improving the haploidentical hematopoietic stem cell transplantation. (2013) (5)
Receptor modulation and functional activation of human CD34+Lin−‐derived immature NK cells in vitro by Mycobacterium bovis Bacillus Calmette‐Guerin (BCG) (2012) (5)
NK Cell Precursors in Human Bone Marrow in Health and Inflammation (2019) (5)
Hematopoietic stem cell transplantation : Improving alloreactive Bw 4 donor selection by genotyping codon 86 of KIR 3 DL 1 / S 1 (2016) (5)
Stromal-like Wilms tumor cells induce human Natural Killer cell degranulation and display immunomodulatory properties towards NK cells (2021) (4)
Unsung Hero Robert C. Gallo (2009) (4)
Characterization of KIR + NK cell subsets with a monoclonal antibody selectively recognizing KIR2DL1 and blocking the specific interaction with HLA‐C (2022) (4)
Expression of HLA class l‐specific inhibitory receptors by chronically activated cytolytic T lymphocytes: useful or harmful to the host? (1997) (4)
What we know and still ignore on COVID‐19 immune pathogenesis and a proposal based on the experience of allergic disorders (2021) (4)
Regulation of myeloid cell proliferation and survival by p75/AIRM1 and CD33 surface receptors. (2001) (4)
Ck226: a novel surface molecule involved in human t cell activation (1989) (4)
Interleukin-2-Induced proliferation of CD4-CD8- human thymocytes.In vitro expression of CD3 and CD8 antigens and cytolytic activity (1988) (4)
ANALYSIS OF SURFACE PROPERTIES, FINE STRUCTURE AND ORGAN DISTRIBUTION OF TWO DISTINCT T-CELL SUBPOPULATIONS: Tμ AND Tγ (1977) (4)
Physical and functional association of CD45 and CD3-TCR complex on CD1+ human thymocytes. Evidence that the engagement of CD45 molecules can prevent CD1+ thymocytes from apoptosis. (1996) (4)
Transplantation Induces Profound Changes in the Transcriptional Asset of Hematopoietic Stem Cells: Identification of Specific Signatures Using Machine Learning Techniques (2020) (4)
The effects of IgM rheumatoid factor on EAM and EAG rosette formation with Fc receptor-bearing lymphoid cells. (1983) (4)
Anti-Leukemia Activity of Alloreactive NK Cells in Haploidentical HSCT in Pediatric Patients: Re-Defining the Role of Activating and Inhibitory KIR (2008) (3)
Human T lymphocytes subpopulation as defined by alloantigens and FC receptors a comparative analysis. (1981) (3)
Immunoregulatory subpopulations of human T lymphocytes. (1979) (3)
Clinical Outcome after Adoptive Infusion of BPX-501 Cells (donor T cells transduced with iC9 suicide gene) in Children Given Alpha/Beta T-Cell Depleted HLA-Haploidentical Hematopoietic Stem Cell Transplantation (haplo-HSCT): Preliminary Results of a Phase I-II Trial (2015) (3)
T cell subpopulations after allogeneic bone marrow transplantation. (1980) (3)
Phenotypic and functional heterogeneity of human T cell clones producing γ-interferon (1985) (3)
The C gamma 1-encoded disulphide-linked and the C gamma 2-encoded nondisulphide-linked forms of the gamma/delta heterodimer use different gamma and delta variable regions. (1990) (3)
T gamma delta-cell subsets in cord and adult blood. (1990) (3)
Helper Innate Lymphoid Cells in Allogenic Hematopoietic Stem Cell Transplantation and Graft Versus Host Disease (2020) (3)
TIGIT Blockade and IL15 in Tumor Immunotherapy: Together is Better (2020) (3)
Interleukin-2 production in response to phytohemagglutinin is not necessarily dependent upon the T3-mediated pathway of T-cell activation. (1986) (3)
A novel pathway of human B cell activation initiated by CK226 surface antigen (1990) (3)
IL-12 or IL-4 prime human natural killer cells to mediate functionally divergent interactions with dendritic cells or tumors (2005) (3)
The management of paediatric allergy: not everybody's cup of tea – 10–11th February 2012 (2013) (3)
T gamma delta cells and their subsets in blood and synovial tissue from rheumatoid arthritis patients. (1990) (3)
Update on natural killer cells: cross-talk with dendritic cells and role in the cure of acute myeloid leukemias. (2003) (3)
Circulating LAK-1 cells and autologous mixed lymphocyte reaction in patients with hepatocellular carcinoma. (1989) (3)
Specific functions of human NK cells. (1992) (3)
Corticoresistant nephrotic syndrome associated with T-cell deficiency in two sisters. (1983) (2)
Human RORgtCD34 Cells Are Lineage-Specified Progenitors of Group 3 RORgt Innate Lymphoid Cells (2019) (2)
Immunotherapy targeting inhibitory checkpoints: The role of NK and other innate lymphoid cells. (2022) (2)
Melanoma Cells Inhibit NK Cell Functions—Response (2012) (2)
Children with Acute Leukemia Given Hematopoietic Stem Cell Transplantation (HSCT) from an HLA-Compatible Sibling, or an Unrelated Donor (UD) or an HLA-Haploidentical Relative after Alpha/Beta T-Cell Depletion Have a Comparable Outcome (2015) (2)
Nectin-2 (CD112) evidence for the involvement of the Poliovirus receptor (CD155) and mediated lysis of freshly isolated myeloid or lymphoblastic leukemias: - Analysis of the receptor-ligand interactions in the natural killer (2013) (2)
Correction: PD-L1 expression heterogeneity in non-small cell lung cancer: evaluation of small biopsies reliability (2018) (2)
Natural Killer Cells in Healthy and Diseased Subjects (2011) (2)
Thymic origin of some natural killer cells: clonal proliferation of human CD3−16+ cells from CD3−4−8− thymocyte precursors requires the presence of H9 leukemic cells (1992) (2)
Comparison of three validated PD-L1 immunohistochemical assays in urothelial carcinoma of the bladder: interchangeability and issues related to patient selection (2022) (2)
T-Cell Depleted HLA-Haploidentical Allogeneic Hematopoietic Stem Cell Transplantation (haplo-HSCT) Followed By Donor Lymphocyte Infusion with T Cells Transduced with the Inducible Caspase 9 (iC9) Suicide Gene in Children with Hematological Malignancies (2016) (2)
Mesenchymal Stem Cells Expanded in Human Platelet Lysate Display a Decreased Inhibitory Capacity on T and NK Cell Proliferation and Function: 2382 (2012) (2)
Immunoregulatory T Cell Subpopulations in Man (1980) (2)
IL-1R8 silencing improves the anti-tumor function of freshly isolated human NK cells (2022) (2)
Human T lymphocytes expressing TCR gamma/delta. (1990) (2)
Intraperitoneal infusion of interleukin-2 in patients with malignant ascites: Phenotypic and functional effects on tumor-associated lymphocytes (1988) (2)
Human thymocytes expressing gamma/delta T‐cell receptors (1989) (2)
CYTOLYTIC T LYMPHOCYTES IN MIXED LYMPHOCYTE CULTURE (1981) (2)
T-cell-mediated suppression of hemopoiesis. (1981) (2)
Epitope characterization of a monoclonal antibody that selectively recognizes KIR2DL1 allotypes (2022) (2)
PROLIFERATIVE RESPONSIVENESS OF TWO DISTINCT HUMAN T-CELL SUBPOPULATIONS TO CON A, PHA AND ALLOANTIGENS (1977) (2)
Natural killer cell acceptance of H-2 mismatch bone marrow grafts in transgenic mice expressing HLA-Cw 3 specific killer cell inhibitory receptor ( CD 158 b ) (1997) (2)
Regulatory Interactions of Human T Cells (1980) (2)
Glucocorticoids inhibit human hematopoietic stem cell differentiation toward a common ILC precursor. (2021) (2)
HUMAN CYTOLYTIC CELL CLONES LACKING SURFACE EXPRESSION OF T CELL RECEPTOR a/(3 OR y/S Evidence That Surface Structures Other Than CD3 or CD2 Molecules Are Required for Signal Transduction (2003) (2)
Cell Separation Techniques (1998) (2)
Alessandro Moretta 1953–2018 (2018) (2)
How the Immune System Responds to Allergy Immunotherapy (2022) (2)
The definition of lymphocyte subpopulations: new approaches to an old problem. (1984) (1)
Human Bone Marrow Mesenchymal Stem Cells Support Polyclonal Stimulation of Human B Cells (2007) (1)
IL-1R8: A molecular brake of anti-tumor and anti-viral activity of NK cells and ILC. (2023) (1)
CD8+ NK cells are predominant in chimpanzees, characterized by high NCR expression and cytokine production, and preserved in chronic HIV-1 infection (European Journal of Immunology (2010) 40, 5 DOI: 10.1002/eji. 200940062) (2010) (1)
Myeloid derived suppressor cells in tumor microenvironment: Interaction with innate lymphoid cells. (2022) (1)
Review Article The Emerging Role of HLA-E-Restricted CD8 + TLymphocytesin the Adaptive Immune Response to Pathogens and Tumors (2010) (1)
Regulatory Human T-Cell Subpopulations Defined by Receptors for IgG or IgM (1980) (1)
Natural killer defined haplotypes are associated with particular ancestral haplotypes: implications for bone marrow transplantation. (1993) (1)
Immunology in Italy. (1988) (1)
Persistence of Unintegrated HIV DNA Associates With Ongoing NK Cell Activation and CD34+DNAM-1brightCXCR4+ Precursor Turnover in Vertically Infected Patients Despite Successful Antiretroviral Treatment (2022) (1)
Natural killer cells and cross‐talk with dendritic cells (2004) (1)
Analysis of CD3-associated molecules in CD4− 8− human T cell clones lacking the typical α/β T cell receptor (1987) (1)
Natural killer cells and cross‐talk with dendritic cells (2004) (1)
IRp60 modulates an array of human mast cell functions (2005) (1)
MechanismApoptosis via an NKp46- and Fas-Dependent Human NK Cells Induce Neutrophil (2012) (1)
TCRαβ/CD19 depleted hematopoietic stem cell transplantation from haploidentical donors: dissecting the GvL/GvHD conundrum (2020) (1)
Glycoproteic nature of surface molecules of effector cells with lymphokine‐activated killer (LAK) activity. Evidence that T11, T8 or T3 molecules are not involved in tumor‐cell lysis by LAK effector T cells (1987) (1)
Phenotypic and functional heterogeneity of human T cell clones producing gamma-interferon. (1985) (1)
CHAPTER 25 – SUBPOPULATIONS OF HUMAN T LYMPHOCYTES: FUNCTIONAL CHARACTERISTICS (1979) (1)
Perturbations of NK cell regulatory functions in respiratory allergic diseases (2007) (1)
HIV-1-Infected Animals Cell Phenotype and Function in Long-Term Chimpanzee NK Cells and Conserved NK Differential NKp 30 Inducibility in (2007) (1)
Transplantation of T-Cell Depleted Peripheral Blood Haematopoietic Stem Cells from an HLA-Disparate Family Donor for Children with Hematological Malignancies. (2007) (1)
Effect of interleukin-2 on murine and human B cells (1984) (1)
Recovery Of Gamma/Delta+ T Cells After Transplantation With Alpha-Beta+/CD19+ Lymphocyte Depleted Hematopoietic Stem Cells From HLA-Haploidentical Donors (2013) (1)
Anti-IgE treatment in asthma: galectin-3 as a predictive marker. (2014) (1)
Alessandro Moretta 1953–2018 (2018) (1)
Novel Munc13-4 Mutations in Patients with Hemophagocytic Lymphohistiocytosis. (2005) (1)
Genomic scale analysis of NK cells impact on response to IFN-α (2013) (1)
Correction to IL-1β inhibits ILC3 while favoring NK-cell maturation of umbilical cord blood CD34+ precursors [Eur. J. Immunol, 45, 7, (2015)] DOI 10.1002/eji.201445326 (2015) (1)
CHAPTER 14 – CLINICAL RELEVANCE OF SUBPOPULATIONS OF HUMAN T LYMPHOCYTES (1979) (1)
Molecular heterogeneity of the 1.0-kb T beta transcript in natural killer and gamma/delta lymphocytes. (1991) (1)
Natural killer cell immune regulation: Coordination of immune function in tissues (2010) (1)
Plenary and Keynote Speakers Summaries (2013) (1)
Neuroblastoma Tumor-Associated Mesenchymal Stromal Cells Regulate the Cytolytic Functions of NK Cells (2022) (1)
Functional and morphologic characterization of human T lymphocytes expressing the TCR gamma /delta (1992) (1)
Erratum: Methylprednisolone induces preferential and rapid differentiation of CD34+ cord blood precursors toward NK cells (International Immunology (2008) vol. 20 (565-575)) (2008) (1)
Su.103. Phenotipic and Functional Characterization of Human Decidual Natural Killer Cells (2008) (1)
Ancestral haplotypes predict EC-1 alleles. (1992) (1)
Seminars in Immunology. New vistas on NK cell development and function. Preface. (2014) (1)
Involvement of T3 and T8 molecules in human T cell receptor function. Anti‐T3 or anti‐T8 antibodies do not block the antigen‐dependent activation of a subset of alloreactive cytolytic T cell precursors (1985) (1)
The tumor microenvironment drives NK cell metabolic dysfunction leading to impaired antitumor activity (2022) (1)
Critical for Staining Identification of the Amino Acid Residues Monoclonal Antibody Reactivity : KIR 2 DL 3 Alleles Displaying Unexpected Cell Ig-Like Receptor Analyses Reveal Combined Genotypic and Phenotypic Killer (2010) (1)
Alpha/Beta T-Cell and B-Cell Depletion HLA-Haploidentical Hematopoietic Stem Cell Transplantation Is an Effective Treatment for Children/Young Adults with Acute Leukemia (2018) (1)
Relationship between expression of Fcγ receptors or la antigens and cytolytic activities of alloactivated human T cells (1983) (1)
MiR‐22, a serum predictor of poor outcome and therapy response in diffuse large B‐cell lymphoma patients (2021) (1)
Vito Pistoia (1949-2018). (2018) (0)
MESENCHYMAL STEM CELLS INHIBIT MONOCYTE-DERIVED DENDRITIC CELL MATURATION AND FUNCTION BY SELECTIVELY INTERFERING WITH THE GENERATION OF IMMATURE DENDRITIC CELLS. CENTRAL ROLE OF MSC-DERIVED PROSTAGLANDIN E2.: 1669 (2010) (0)
HO-1 and GSH mediate cancer cell resistance to Bortezomib : role of Nrf 2 (2014) (0)
Legends of allergy and immunology: Giorgio Walter Canonica—Physician, scientist, and visionary leader (2021) (0)
NK-type lymphoproliferative disease of granular lymphocytes Phenotypic diversity of natural killer (NK) populations in patients with (2011) (0)
immune-mediated marrow failure Generation of CFU-C/suppressor T cells in vitro: an experimental model for (2011) (0)
Editorial Board: Eur. J. Immunol. 10'15 (2015) (0)
HIV-1-infected animals phenotype and function in long-term chimpanzee NK cells and conserved NK cell Differential NKp 30 inducibility in (2007) (0)
Innate immune effectors in cancer. (2023) (0)
Editorial Board: Eur. J. Immunol. 1'17 (2017) (0)
Inherent transcriptional signatures of NK cells are associated with response to IFNα + rivabirin therapy in patients with Hepatitis C Virus (2015) (0)
Defective CD107a Surface Expression Heralds Munc13-4 Defect and Discriminates between Genetic Subtypes of Familial Hemophagocytic Lymphohistiocytosis (FHL). (2006) (0)
Editorial Board: Eur. J. Immunol. 12'16 (2016) (0)
Surface markers of resting and activated human T cells. Functional implications and experimental limits (2005) (0)
Errartum: IFN-α-mediated increase in cytolytic activity of maturing NK cell upon exposure to HSV-infected myelomonocytes (European Journal of Immunology (2009) vol. 39 (1) 10.1002/eji.200838532) (2009) (0)
SURFACE RECEPTORS MEDIATING HUMAN NK CELL TRIGGERING OR INHIBITION (1998) (0)
Role of HO‐1 in neuroblastoma resistance to Bortezomib (2013) (0)
Natural killer cells carry the germ-line configuration of the T cell receptor delta chain gene and heterogeneously express six distinct delta transcripts. (1990) (0)
IL-15-induced expression of the CD94/NKG2a HLA-class I-specific inhibitory receptors in NK cells derived from early thymic precursors (1997) (0)
Su.64. Natural Killer Cell-mediated Recognition of Human Brain Tumors (2008) (0)
Title Page / Contents / Preface (1996) (0)
Running title : Multiple interactions of NK cells with DCs (2006) (0)
Separation, phenotyping and cloning of tumor infiltrating lymphocytes from human solid tumors (1986) (0)
Identification of a functional T-cell population by the use of surface markers: present limitations and new strategies. (1982) (0)
Bone marrow transplantation and graft versus host disease (WS-077) Chairpersons: Takanori Teshima, Juan Carlos Zúñiga-Pflücker (2010) (0)
Table of Contents (2013) (0)
Uptake of CCR7 by KIR2DS4+ NK cells is induced upon recognition of certain HLA-C alleles: implication of activating KIRs in haploidentical HSCT (2015) (0)
Legends of allergy and immunology: Alberto Mantovani, a visionary scientist unraveling the complexity of innate immunity in cancer and inflammation (2022) (0)
Induction of anti-tumor immune response by bispecific monoclonal antibodies (bimAbs). (1992) (0)
Analysis of CD8 T-cells recognising Mycobacterium tuberculosis antigen presented by HLA-E molecule (2014) (0)
Natural Killer Cell Effector Mechanisms Against Solid Tumors and Leukemias and Their Exploitation in Immunotherapy (2021) (0)
LymphSecondary Lymphoid Organs via Afferent Neoplastic Solid Tissues and Recirculate to NK Cells Are Abundant in Both Healthy and Noncytotoxic Human low Perforin bright CD56 (2014) (0)
Recent Progress in Human Natural Killer Cell Ontogeny (1994) (0)
Nrf2/HO-1 up-regulation in neuroblastoma cell survival (2014) (0)
The activating form of the CD94 receptor complex. The CD94 associated Kp39 protein represents the product of NKG2-C gene. (1998) (0)
Fc receptors on human T lymphocytes: loss of Fc mu and expression of Fc gamma receptors by T cells stimulated in mixed lymphocyte reaction. (1981) (0)
Patterns of immune reconstitution after human bone marrow transplantation (1988) (0)
Energetic and structural basis of sialylated oligosaccharide recognition by the natural killer cell inhibitory receptor p75/AIRM1 or Siglec-7 (2003) (0)
TWO DISTINCT HUMAN T-CELL SUBPOPULATIONS: SUPPRESSOR ACTIVITY ON PWM-INDUCED B-CELL DIFFERENTIATION IS RESTRICTED TO T CELLS BEARING Fc-IgG RECEPTORS (1977) (0)
OR.69. Hla-E-Restricted Cytolytic T Lymphocytes: Their Role in Cytomegalovirus Infection and Transplantation (2006) (0)
Role of Nrf2 in neuroblastoma sensitivity to Bortezomib (2012) (0)
Author response for "Human NK cells, their receptors and function" (2021) (0)
cells interaction receptor (CD155) on dendritic cells: relevance for Natural Killer/dendritic Expression of the DNAM-1 ligands Nectin-2 (CD112) and poliovirus (2011) (0)
NK-dependent DC maturation is mediated by TNF (cid:1) and IFN (cid:2) released upon engagement of the NKp30 triggering receptor (2005) (0)
Defective CD 107 a surface expression heralds Munc 13-4 defect and discriminates between genetic subtypes of the disease . Running title : NK cells and CD 107 a expression in FHL (2006) (0)
CD56 Is a Pathogen Recognition Receptor on Human Natural Killer Cells (2017) (0)
Future directions in human immunobiology. (1985) (0)
Human T lymphocyte markers and function: A major research goal of the group working at the Cancer Institute in Genova (Laboratory of Immunopathology) (1988) (0)
PD-1 is expressed by and regulates human group 3 innate lymphoid cells in human decidua (2019) (0)
NKG 2 D-dependent Natural Killer Cell Cytotoxicity Different Histotypes : Analysis of Tumor Susceptibility to UL 16-Binding Protein Expression on Tumor Cell Lines of Major Histocompatibility Complex Class I-related Chain A and Updated (2002) (0)
OR.69. Alloreactive NK Cells Exert Anti-leukemia Activity in Haplo-HSCT to Pediatric Patients: Revised Role of Activating and Inhibitory KIR (2009) (0)
Title Pages / Table of Contents (1996) (0)
Editorial Board: Eur. J. Immunol. 10'16 (2016) (0)
Cell therapy (SY5-1) Chairpersons: Masaru Taniguchi, Jacques Banchereau (2010) (0)
Foreword. New frontiers in molecular and cellular therapy. (2013) (0)
Corrigendum to ‘Understanding human NK cell differentiation: Clues for improving the haploidentical hematopoietic stem cell transplantation’ [Immunol. Lett. 155 (2013) (1–2) 2–5] (2014) (0)
Contents, Vol. 99, 1992 (1992) (0)
Extracellular region of the human receptor NKp46 (2003) (0)
ILC3s: Rhythmic Keepers of Gut Integrity at Mealtime. (2020) (0)
Negative regulation of T and NK cells (1998) (0)
Siglec-7, a target for novel therapeutical approaches of Systemic Mastocytosis. (2020) (0)
Brief Definitive Report ANTIBODY-INDUCED MODULATION OF THE CD3/T CELL RECEPTOR COMPLEX CAUSES T CELL REFRACTORINESS BY INHIBITING THE EARLY METABOLIC STEPS INVOLVED IN T CELL ACTIVATION (1987) (0)
The Latest Approach of Immunotherapy with Endosomal TLR Agonists Improving NK Cell Function: An Overview (2022) (0)
Novel isoforms of peroxiredoxin 5 encode a unique melanoma antigen and can provide dual-binding peptides for classical and nonclassical HLA molecules (2006) (0)
Brief Definitive Report CHARACTERIZATION OF CD 3 + , CD 4-, CD 8-CLONES EXPRESSING THE PUTATIVE T CELL RECEPTOR , y GENE PRODUCT Analysis of the Activation Pathways Leading to Interleukin 2 Production and Triggering of the Lytic Machinery (2003) (0)
A novel putative inhibitory NK receptor belonging to the immunoglobulin-superfamily (1997) (0)
Phenotypic and functional characterization of human T lymphocytes expressing a gamma/delta T cell antigen receptor. (1989) (0)
Contents Vol. 164, 2014 (2014) (0)
Analysis of CD3-associated molecules in CD4- 8- human T cell clones lacking the typical alpha/beta T cell receptor. (1987) (0)
Hunan T cell subpopulations in normal and pathologic conditions. (1979) (0)
Corrigendum to: Histone deacetylase inhibitors sensitize tumour cells for cytotoxic effects of natural killer cells (2009) (0)
KIR Workshop 25th‐27th October 2018 ‐ Camogli (GE) Italy (2019) (0)
Receptors involved in human NK cell activation in the process of natural cytotoxicity (2001) (0)
Cell Function during Simian HIV Infection Cynomolgus Macaques: Monitoring of NK NK Cell Receptors in Rhesus and of NKG2D, NKp80, and NKG2C Triggering Molecular and Functional Characterization (2005) (0)
Heterogeneity of B cell growth factor (BCGF)-producing T cells in humans. Clonal analysis of BCGF-producing cells within T4+ and T8+ subsets and evidence for the involvement of different growth factors in different BCGF assays (1986) (0)
MHC CLASS I-SPECIFIC INHIBITORY RECEPTORS EXPRESSED BY NK AND T LYMPHOCYTES (2000) (0)
Epithelial cell Neuron Bone marrowBone MSC Self-renewal Ectoderm Fat cell Bone cell Muscle cell Gut epithelial cell Mesoderm Cartilage cell (0)
MESENCHYMAL STEM CELLS INHIBIT NATURAL KILLER CELL PROLIFERATION, CYTOTOXICITY AND CYTOKINE PRODUCTION: ROLE OF INDOLEAMINE 2,3-DIOXYGENASE AND PROSTAGLANDIN E2.: 1746 (2010) (0)
Familial hemophagocytic lymphohistiocytosis: a model for understanding the human machinery of cellular cytotoxicity (2011) (0)
GM-CSF, and eotaxin on human peripheral blood eosinophils The inhibitory receptor IRp60 (CD300a) suppresses the effects of IL-5, (2012) (0)
HO-1 down-regulation increases the efficacy of BRAFV600E inhibition-based therapy in primary melanoma cells (2016) (0)
Human peripheral blood eosinophils express functional CD2-subfamily immunoglobulin receptors (2004) (0)
Difficulties and new strategies in the identification of functional T cell populations in humans. (1983) (0)
SpecificRecognitionofHuman CD3 -CD16+ Natural KillerCellsRequirestheExpressionofan Autosomic RecessiveGene on TargetCells (1990) (0)
Mobilization of healthy donors with plerixafor affects the cellular composition of T-cell receptor (TCR)-αβ/CD19-depleted haploidentical stem cell grafts (2014) (0)
displays either inhibitory or stimulatory function from CD3+ lymphoproliferative disease of granular lymphocytes The natural killer-related receptor for HLA-C expressed on T cells (2011) (0)
Function in Long-Term HIV-1-Infected Animals NK Cells and Conserved NK Cell Phenotype and Differential NKp30 Inducibility in Chimpanzee (2011) (0)
Relationship between expression of Fc gamma receptors or Ia antigens and cytolytic activities of alloactivated human T cells. (1983) (0)
Reply to Garaci and Pocchiari (1989) (0)
CPHEN-15: Comprehensive phenotyping of human peripheral blood helper-ILCs by flow cytometry. (2023) (0)
Interleukin 2 and interferon-gamma are not sufficient to induce natural killer-like activity in human T cell clones. (1984) (0)
Human lymphocytes expressing a TCR gamma/delta. (1990) (0)
Natural killer recognition of primary melanoma cells treated with BRAFV600E inhibitor is favored by heme oxygenase 1 down-regulation (2018) (0)
Therapeutic compositions for cancer, that target 4Ig-B7-H3 (2005) (0)
癌細胞増殖と化学抵抗性におけるNrf2/HO‐1軸 (2016) (0)
can impair processing to the active form of perforin A single amino acid change, A91V, leads to conformational changes that (2013) (0)
44-OR: Recognition of HLA-E by natural killer cells is impacted by variation in cytomegalovirus UL40 sequences in haemopoietic stem cell transplantation (2009) (0)
In vitro immuno globulin production is not inhibited by t derived colony inhibitory activity (1983) (0)
Therapeutic and diagnostic methods and compositions for the targeting of 4ig-B7-H3 and its corresponding NK cell receptor (2005) (0)
Lorenzo Moretta 2 of MSC-derived prostaglandin E selectively interfering with the generation of immature DCs : central role MSCs inhibit monocyte-derived DC maturation and function (2009) (0)
Different effects of NK cells and NK-derived soluble factors on cell lines derived from primary or metastatic pancreatic cancers. (2022) (0)
Recognition of the non-classical MHC class I molecule, HLA-E, by the adaptive immune system (2005) (0)
MUNC13–4 Mutations in Patients with Hemophagocytic Lymphohistiocytosis Are Scattered over the Functional Domains of the Protein. (2006) (0)
Surface molecules involved in antigen independent cell activation (1988) (0)
Both the precursors and the effectors of human lymphokine-activated killer (LAK) cells may belong to T lymphocytes (1986) (0)
Molecular studies on LAK cells. (1990) (0)
A vision of immuno-oncology: the Siena think tank of the Italian network for tumor biotherapy (NIBIT) foundation (2021) (0)
with Dendritic Cells or Tumors Mediate Functionally Divergent Interactions IL-12 or IL-4 Prime Human NK Cells to (2005) (0)
IRp60 is expressed and functional on human cord blood derived mast cells (2004) (0)
Molecular definition of group 1 innate lymphoid cells in the mouse uterus (2018) (0)
1073 Neuroblastoma Cells Modulate Chemokine Receptor Repertoire of Resting NK Cells (2012) (0)
Surface Phenotype of Helper and Suppressor Human T Cell Clones (1983) (0)
HLA-G-specific receptors in human NK or T lymphocytes (1997) (0)
blasts human NK cells interacting with allogeneic HLA-C2+ DCs or T-cell KIR2DS1-dependent acquisition of CCR7 and migratory properties by (2013) (0)
Expression of the DNAM-1 ligands Nectin-2 (CD112) and Poliovirus receptor (CD155) on dendritic cells: relevance for Natural Killer/dendritic cells interaction. Running title: Nectin-2 and PVR expression on DC (2005) (0)
NK cells provide a helper signal for CTL by inducing membrane-bound IL-15 on DCs: implications for cancer vaccines (2006) (0)
responses plasmacytoid and monocyte-derived dendritic cells during innate immune Multidirectional interactions are bridging human NK cells with (2013) (0)
[Membrane markers and T-lymphocyte subpopulations (limits and prospects)]. (1981) (0)
shuttling to early endosomes is mediated by KIR3DL2 A novel KIR-associated function: evidence that CpG DNA uptake and (2011) (0)
Human Natural Killer ( NK ) Alloreactivity and Its Association with the Major Histocompatibility Complex : Ancestral Haplotypes Encode Particular NK-defmed Haplotypes (2003) (0)
Receptors for the Fc fragment of IgG on human peripheral blood lymphocytes in culture. (1974) (0)
In vivo generation of patient-specific cytotoxic T cell clones (CTL), following donor lymphocyte infusions (DLI) for chronic myeloid leukemia after HLA genotypically identical BMT (1999) (0)
ReviewThe immune checkpoint PD-1 in Natural Killer cells: expression (2020) (0)
In memory of Vito Pistoia (1949–2018) (2018) (0)
GM-CSF in oncology: Limits and possibilities: ANM consensus meeting - Rome, 14 September 1994 (1994) (0)
Human natural killer cell ontogeny, specificity and receptors (1994) (0)
Recent Advances in Human Natural Killer Cells. (1992) (0)
Preface (0)
Dendritic cells: function (PP-024) (2010) (0)
NK cells and NK receptors (WS-007) Chairpersons: Hisashi Arase, Noriko Toyama-Sorimachi (2010) (0)
lymphohistiocytosis in siblings carryingPRF1 mutations Adult onset and atypical presentation of hemophagocytic (2013) (0)
Immune Reconstitution after Adoptive Infusion of BPX501 Cells (donor T cells transduced with iC9 suicide gene) in Children Given Alpha/Beta T-Cell Depleted HLA-Haploidentical Hematopoietic Stem Cell Transplantation (haplo-HSCT): Preliminary Phenotypic and Functional Results of a Phase I-II Trial (2015) (0)
Effect of Melanoma-derived Fibroblasts on NK Cell Phenotype and Functions (2010) (0)
Functional analysis of cell variants lacking molecules involved in t cell activation (1987) (0)
NKG2 molecules assemble with CD94 to form HLA-specific NK receptors (1997) (0)
On the pathogenesis of perforin defects and related immunodeficiencies. (2000) (0)
Clonal Analysis of Human T Lymphocytes Inducing B Cell Growth (1986) (0)
NKp46 and NKG2D activating receptors and regulates NK cell function The tryptophan catabolite L-kynurenine inhibits the surface expression of (2013) (0)
Clonal analysis of the involvement of T11 molecules in antigen receptor-mediated T lymphocyte functions. (1985) (0)
Generation of CFUC suppressor T cells in vitro: VII. T derived colony inhibitory activity (Td/CIA) has no suppressor effect on in vitro immunoglobulin production. (1983) (0)

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