Louise Johnson
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British biochemist and protein crystallographer
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Biochemistry
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Molecular Biology
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Biology
Louise Johnson's Degrees
- PhD Biochemistry University of Oxford
- Bachelors Chemistry University of Oxford
Why Is Louise Johnson Influential?
(Suggest an Edit or Addition)According to Wikipedia, Dame Louise Napier Johnson, , was a British biochemist and protein crystallographer. She was David Phillips Professor of Molecular Biophysics at the University of Oxford from 1990 to 2007, and later an emeritus professor.
Louise Johnson's Published Works
Published Works
- Active and Inactive Protein Kinases: Structural Basis for Regulation (1996) (1346)
- Protein Kinase Inhibitors: Insights into Drug Design from Structure (2004) (1143)
- The structural basis for specificity of substrate and recruitment peptides for cyclin-dependent kinases (1999) (536)
- Structural basis for control by phosphorylation. (1997) (493)
- The structural basis for control of eukaryotic protein kinases. (2012) (379)
- Glycogen phosphorylase: control by phosphorylation and allosteric effectors (1992) (312)
- The structure of P‐TEFb (CDK9/cyclin T1), its complex with flavopiridol and regulation by phosphorylation (2008) (291)
- The regulation of protein phosphorylation. (2009) (285)
- The effects of phosphorylation on the structure and function of proteins. (1993) (268)
- Structural changes in glycogen phosphorylase induced by phosphorylation (1988) (263)
- The allosteric transition of glycogen phosphorylase (1989) (260)
- 21 Vertebrate Lysozymes (1972) (258)
- The crystal structure of triacylglycerol lipase from Pseudomonas glumae reveals a partially redundant catalytic aspartate (1993) (248)
- Protein kinase inhibitors: contributions from structure to clinical compounds (2009) (243)
- The crystal structure of the human polo‐like kinase‐1 polo box domain and its phospho‐peptide complex (2003) (235)
- Protein kinase inhibition by staurosporine revealed in details of the molecular interaction with CDK2 (1997) (220)
- Effects of Phosphorylation of Threonine 160 on Cyclin-dependent Kinase 2 Structure and Activity* (1999) (220)
- Structural mechanism for glycogen phosphorylase control by phosphorylation and AMP. (1992) (218)
- Phototransformation of green fluorescent protein with UV and visible light leads to decarboxylation of glutamate 222 (2002) (205)
- CAK—Cyclin-Dependent Activating Kinase: A Key Kinase in Cell Cycle Control and a Target for Drugs? (2005) (202)
- Structure-based design of a potent purine-based cyclin-dependent kinase inhibitor (2002) (196)
- The crystal structure of cyclin A. (1995) (196)
- Identification of novel purine and pyrimidine cyclin-dependent kinase inhibitors with distinct molecular interactions and tumor cell growth inhibition profiles. (2000) (193)
- Structure of Some Crystalline Lysozyme-Inhibitor Complexes Determined by X-Ray Analysis At 6 Å Resolution (1965) (192)
- The crystal structure of a phosphorylase kinase peptide substrate complex: kinase substrate recognition (1997) (186)
- The structural basis for substrate recognition and control by protein kinases 1 (1998) (183)
- Phosphoprotein-protein interactions revealed by the crystal structure of kinase-associated phosphatase in complex with phosphoCDK2. (2001) (173)
- Specificity determinants of recruitment peptides bound to phospho-CDK2/cyclin A. (2002) (156)
- Crystal structure of a lysozyme-tetrasaccharide lactone complex. (1974) (141)
- The structure of cyclin E1/CDK2: implications for CDK2 activation and CDK2‐independent roles (2005) (136)
- Two structures of the catalytic domain of phosphorylase kinase: an active protein kinase complexed with substrate analogue and product. (1995) (135)
- Crystallographic studies on the activity of glycogen phosphorylase b (1978) (131)
- Design of a diffractometer and flow cell system for X-ray analysis of crystalline proteins with applications to the crystal chemistry of ribonuclease-S. (1967) (131)
- The crystal structure of human CDK7 and its protein recognition properties. (2004) (124)
- The cyclin box fold: protein recognition in cell-cycle and transcription control. (1997) (124)
- POTENT INHIBITION OF GLYCOGEN PHOSPHORYLASE BY A SPIROHYDANTOIN OF GLUCOPYRANOSE : FIRST PYRANOSE ANALOGUES OF HYDANTOCIDIN (1995) (123)
- Control by phosphorylation. (1996) (119)
- High resolution1H- and13C-N.M.R spectra ofD-glucopyranose, 2-acetamido-2-deoxy-D-glucopyranose, and related compounds in aqueous media (1977) (118)
- A new allosteric site in glycogen phosphorylase b as a target for drug interactions. (2000) (115)
- Flavopiridol Inhibits Glycogen Phosphorylase by Binding at the Inhibitor Site* (2000) (112)
- Glucose analogue inhibitors of glycogen phosphorylase: the design of potential drugs for diabetes. (1991) (112)
- Two different conformational states of the KirBac3.1 potassium channel revealed by electron crystallography. (2005) (111)
- Millisecond X-ray diffraction and the first electron density map from Laue photographs of a protein crystal (1987) (108)
- Comparison of the binding of glucose and glucose 1-phosphate derivatives to T-state glycogen phosphorylase b. (1992) (99)
- Catalysis in the crystal: synchrotron radiation studies with glycogen phosphorylase b. (1987) (97)
- Design of inhibitors of glycogen phosphorylase: a study of alpha- and beta-C-glucosides and 1-thio-beta-D-glucose compounds. (1994) (97)
- The Role of the Phospho-CDK2/Cyclin A Recruitment Site in Substrate Recognition* (2006) (95)
- Halogen bonds form the basis for selective P-TEFb inhibition by DRB. (2010) (94)
- Structure-based design of cyclin-dependent kinase inhibitors. (2002) (92)
- Structural analysis of the anaphase-promoting complex reveals multiple active sites and insights into polyubiquitylation. (2005) (90)
- Phosphorylase recognition and phosphorolysis of its oligosaccharide substrate: answers to a long outstanding question (2000) (90)
- The structure of a glycogen phosphorylase glucopyranose spirohydantoin complex at 1.8 Å resolution and 100 K: The role of the water structure and its contribution to binding (1998) (85)
- Structures of the Dsk2 UBL and UBA domains and their complex. (2006) (80)
- Probing the ATP ribose-binding domain of cyclin-dependent kinases 1 and 2 with O(6)-substituted guanine derivatives. (2002) (80)
- Cyclin B and Cyclin A Confer Different Substrate Recognition Properties on CDK2 (2007) (79)
- Refined crystal structure of the phosphorylase-heptulose 2-phosphate-oligosaccharide-AMP complex. (1990) (78)
- Protein-oligosaccharide interactions: lysozyme, phosphorylase, amylases. (1988) (77)
- Structure of daidzin, a naturally occurring anti-alcohol-addiction agent, in complex with human mitochondrial aldehyde dehydrogenase. (2008) (73)
- The structure of ribonuclease-S at 6 A resolution. (1967) (73)
- The crystal structure of Escherichia coli maltodextrin phosphorylase provides an explanation for the activity without control in this basic archetype of a phosphorylase (1997) (73)
- Structural Basis for Control by Phosphorylation (2001) (72)
- The Eleventh Datta Lecture. The structural basis for substrate recognition and control by protein kinases. (1998) (72)
- Structure of human transthyretin complexed with bromophenols: a new mode of binding. (2000) (72)
- Crystal structure of the cell cycle-regulatory protein suc1 reveals a beta-hinge conformational switch. (1995) (72)
- Alternative binding modes of an inhibitor to two different kinases. (2003) (71)
- The crystal structure of p13suc1, a p34cdc2‐interacting cell cycle control protein. (1995) (71)
- Catalytic mechanism of phosphorylase kinase probed by mutational studies. (1999) (70)
- Glycogen phosphorylase. The structural basis of the allosteric response and comparison with other allosteric proteins. (1990) (70)
- Neutron diffraction investigations of L- and D-alanine at different temperatures: the search for structural evidence for parity violation (2005) (69)
- The structure of glycogen phosphorylase b with an alkyldihydropyridine-dicarboxylic acid compound, a novel and potent inhibitor. (1997) (67)
- Crystal structure of the mutant D52S hen egg white lysozyme with an oligosaccharide product. (1995) (65)
- Ternary complex crystal structures of glycogen phosphorylase with the transition state analogue nojirimycin tetrazole and phosphate in the T and R states. (1996) (64)
- Structural studies with inhibitors of the cell cycle regulatory kinase cyclin-dependent protein kinase 2. (2002) (63)
- The crystal structure of phosphorylase beta at 6 A resolution. (1974) (63)
- Subunit structure of aldolase: chemical and crystallographic evidence. (1969) (63)
- The structure of ribonuclease-S at 3.5 A resolution. (1967) (60)
- Glucose analogue inhibitors of glycogen phosphorylase: from crystallographic analysis to drug prediction using GRID force-field and GOLPE variable selection. (1995) (60)
- Progress with Laue diffraction studies on protein and virus crystals. (1990) (59)
- N‐acetyl‐β‐D‐glucopyranosylamine: A potent T‐state inhibitor of glycogen phosphorylase. A comparison with α‐D‐glucose (1995) (57)
- Low-resolution structure of the glycogen phosphorylase a monomer and comparison with phosphorylase b (1976) (57)
- Oligosaccharide substrate binding in Escherichia coli maltodextrin phosphorylase (1997) (56)
- Simulation of diffusion time of small molecules in protein crystals. (2006) (52)
- Macromolecular crystallography. Part A. Methods in Enzymology, Vol. 276. Edited by Charles W. Carter Jr and Robert M. Sweet. New York: Academic Press, 1997. Pp. xxxii + 700. Price $99.00. ISBN 0-12-182177-3 (1998) (52)
- Substrate-cofactor interactions for glycogen phosphorylase b: a binding study in the crystal with heptenitol and heptulose 2-phosphate. (1984) (49)
- Proposals for the catalytic mechanism of glycogen phosphorylase beta prompted by crystallographic studies on glucose 1-phosphate binding. (1980) (48)
- Crystallization of pig skeletal phosphorylase b. Purification, physical and catalytic characterization. (1985) (47)
- Nucleotide binding to glycogen phosphorylase b in the crystal. (1979) (47)
- Structural basis for substrate recognition and control in protein kinases. (2001) (46)
- The molecular mechanism for the tetrameric association of glycogen phosphorylase promoted by protein phosphorylation (1992) (46)
- Structural studies on phospho-CDK2/cyclin A bound to nitrate, a transition state analogue: implications for the protein kinase mechanism. (2002) (45)
- Mutational analysis supports a structural model for the cell cycle protein kinase p34. (1994) (45)
- Catalysis in enzyme crystals. (1988) (44)
- Crystallographic binding studies on the allosteric inhibitor glucose-6-phosphate to T state glycogen phosphorylase b. (1993) (43)
- Enzymatic catalysis in crystals of Escherichia coli maltodextrin phosphorylase. (2002) (41)
- Comparison of AMP and NADH binding to glycogen phosphorylase b. (1983) (40)
- Changes in absorption spectrum and crystal structure of triose phosphate isomerase brought about by 2-phosphoglycollate, a potential transition state analogue. (1970) (39)
- The crystal structure of N-acetyl-a-D-glycosamine (1966) (38)
- 4-Alkoxy-2,6-diaminopyrimidine derivatives: inhibitors of cyclin dependent kinases 1 and 2. (2003) (38)
- Glycogen Phosphorylase B: Description of the Protein Structure (1991) (37)
- The binding of monosaccharide inhibitors to hen egg-white lysozyme by proton magnetic resonance at 270 MHz and analysis by ring-current calculations. (1981) (37)
- Plk1 activation by Ste20-like kinase (Slk) phosphorylation and polo-box phosphopeptide binding assayed with the substrate translationally controlled tumor protein (TCTP). (2008) (36)
- Pyridoxal phosphate site in glycogen phosphorylase b: structure in native enzyme and in three derivatives with modified cofactors. (1987) (34)
- Macromolecular crystallography at synchrotron radiation sources: current status and future developments (2010) (33)
- The Structure of Phosphorylase Kinase Holoenzyme at 9.9 Å Resolution and Location of the Catalytic Subunit and the Substrate Glycogen Phosphorylase (2009) (32)
- Phosphorylase: control and activity. (1981) (32)
- Specific inhibition of glycogen phosphorylase by a spirodiketopiperazine at the anomeric position of glucopyranose (1995) (32)
- Protein kinases and their therapeutic exploitation. (2007) (32)
- Channels at the catalytic site of glycogen phosphorylase b: binding and kinetic studies with the beta-glycosidase inhibitor D-gluconohydroximo-1,5-lactone N-phenylurethane. (1988) (31)
- The early history of lysozyme (1998) (31)
- Exploiting structural principles to design cyclin-dependent kinase inhibitors. (2005) (31)
- Catalytic mechanism of glycogen phosphorylase. (1992) (31)
- Effects of C-1-substituted glucose analogue on the activation states of glycogen synthase and glycogen phosphorylase in rat hepatocytes. (1995) (30)
- Spirohydantoins of glucofuranose: Analogues of hydantocidin (1995) (30)
- Electrostatic effects in the control of glycogen phosphorylase by phosphorylation (1994) (29)
- Methods in macromolecular crystallography (2001) (28)
- Allosteric interactions of glycogen phosphorylase b. A crystallographic study of glucose 6-phosphate and inorganic phosphate binding to di-imidate-cross-linked phosphorylase b. (1984) (28)
- Three-dimensional structure of phosphorylase kinase at 22 A resolution and its complex with glycogen phosphorylase b. (2002) (27)
- Analysis of the structure of Pseudomonas glumae lipase. (1994) (27)
- Molecular Biology of Assemblies and Machines (2016) (26)
- Macromolecular crystallography with synchrotron radiation. II. Results (1983) (26)
- Effects of novel analogues of D-glucose on glycogen phosphorylase activities in crude extracts of liver and skeletal muscle. (1995) (26)
- The distribution of Concanavalin A receptor sites on the membrane of chromaffin granules. (1975) (26)
- The crystal structure of the Escherichia coli maltodextrin phosphorylase-acarbose complex. (1999) (25)
- Structure of some crystalline lysozyme-inhibitor complexes determined by X-ray analysis at 6 Angstrom resolution. (1965) (25)
- Recognition of Cdk2 by Cdk7 (2007) (25)
- Crystal structures of hen egg-white lysozyme complexes with gadolinium(III) and gadolinium(III)-N-acetyl-D-glucosamine. (1979) (24)
- Preliminary crystallographic data for triose phosphate isomerase (1967) (23)
- Stereospecific Synthesis of Spirohydantoins of β-Glucopyranose: Inhibitors of Glycogen Phosphorylase (1997) (23)
- Expression, purification and crystallisation of phosphorylase kinase catalytic domain. (1995) (22)
- Substrates of Mitotic Kinases (2011) (22)
- The distribution of anionic sites on the surface of the chromaffin granule membrane. (1976) (21)
- Effects of commonly used cryoprotectants on glycogen phosphorylase activity and structure (1999) (21)
- Conformational changes, dynamics and assignments in 1H NMR studies of proteins using ring current calculations Hen egg white lysozyme (1977) (21)
- Expression of the phosphorylase kinase γ subunit catalytic domain in Escherichia coli (1992) (20)
- A tetragonal crystal form of phosphorylase b. (1972) (18)
- Glucopyranose Spirohydantoins: Specific Inhibitors of Glycogen Phosphorylase (1997) (17)
- Uridine(5')diphospho(1)-alpha-D-glucose. A binding study to glycogen phosphorylase b in the crystal. (1988) (17)
- Crystal structures of egg-white lysozyme of hen in acetate-free medium and of lysozyme complexes with N-acetylglucosamine and beta-methyl N-acetylglucosaminide. (1978) (17)
- The binding of 2-deoxy-D-glucose 6-phosphate to glycogen phosphorylase b: kinetic and crystallographic studies. (1995) (16)
- α-Azidoesters as divergent intermediates for combinatorial generation of glucofuranose libraries of novel N-linked glycopeptides (1996) (16)
- Crystallographic analysis at low resolution of metabolite binding sites on phosphorylase b (1978) (16)
- The HupR receiver domain crystal structure in its nonphospho and inhibitory phospho states. (2009) (16)
- Time-resolved structural studies on catalysis in the crystal with glycogen phosphorylase b. (1986) (16)
- Structural and functional studies of the response regulator HupR. (2006) (15)
- Glucofuranose analogues of hydantocidin (1996) (15)
- Lipid ordering and enzymic activities in chromaffin granule membranes. (1976) (15)
- The activity of lysozyme: an interim review of crystallographic and chemical evidence. (1968) (13)
- Time-resolved macromolecular crystallography : proceedings of a Royal Society discussion meeting, held on 29 and 30 January 1992 (1992) (13)
- Physical and chemical properties of lysozyme. (1977) (13)
- Time-resolved diffraction studies on glycogen phosphorylase b (1992) (12)
- UPTAKE OF MANGANESE BY CHROMAFFIN GRANULES IN VITRO (1979) (12)
- Asymmetry at the molecular level in biology (2005) (11)
- 7-Carbon mimics of D-glucose and L-fucose: Activation by 6R-, and inactivation by 6S, -6C-methylglucose of glycogen synthase: Inhibition of glucokinase and/or glucose-6-phosphatase (1996) (11)
- The simultaneous binding of lanthanide and N-acetylglucosamine inhibitors to hen egg-white lysozyme in solution by 1H and 13C nuclear magnetic resonance. (1981) (11)
- Control of phosphorylase b conformation by a modified cofactor: Crystallographic studies on R‐state glycogen phosphorylase reconstituted with pyridoxal 5′‐diphosphate (1992) (10)
- Oligosaccharide binding to glycogen phosphorylase b. (1983) (10)
- Structural characterization of Ca2+/CaM in complex with the phosphorylase kinase PhK5 peptide (2005) (9)
- Activator anion binding site in pyridoxal phosphorylase b: The binding of phosphite, phosphate, and fluorophosphate in the crystal (1996) (9)
- An interaction between lysozyme and penicillin (1967) (9)
- Glycogen phosphorylase b - the molecular anatomy of a large regulatory enzyme (1985) (9)
- Freeze-fracture of adrenal chromaffin granules (1977) (8)
- Sulphate-activated phosphorylase b: the pH-dependence of catalytic activity. (1995) (8)
- Control by protein phosphorylation (1994) (8)
- How the structure of lysozyme was actually determined (2006) (8)
- Electron microscopy of phosphorylase b crystals. (1972) (8)
- From phosphorylase to phosphorylase kinase. (1997) (8)
- Cell cycle proteins (1996) (7)
- The binding of flavopiridol to blood serum albumin. (2010) (7)
- Effects of N-acetyl-β-D-glucopyranosylamine on glycogen metabolism by isolated hepatocytes (1995) (7)
- Towards time-resolved diffraction studies with glycogen phosphorylase. (1991) (6)
- Crystal Structure of N-Acetylglucosamine (1964) (6)
- Sugar mimics from sugar lactones (1998) (5)
- Catalysis in the crystal: synchrotron radiation studies with glycogen phosphorylase b (1987) (5)
- The structure and function of lysozyme. (1966) (5)
- Xenopus phospho-CDK7/cyclin H expressed in baculoviral-infected insect cells. (2001) (5)
- Glycogen phosphorylase: A multifaceted enzyme (1989) (5)
- The design of potential antidiabetic drugs: experimental investigation of a number of β-D-glucose analogue inhibitors of glycogen phosphorylase (1994) (5)
- Assignment of the amino acid sequence to the crystal structure of glycogen phosphorylase b. (1978) (4)
- THE CRYSTAL STRUCTURE OF GLYCOGEN PHOSPHORYLASE b (1978) (4)
- X-Ray crystallographic analysis of 2,6-anhydro-N-methyl-D-glycero-D-ido-heptonamide: the first example of a simple glucose analogue with a skew boat structure (1993) (4)
- The structure of the polo box domain of human Plk1 (2003) (3)
- Expression of the phosphorylase kinase gamma subunit catalytic domain in Escherichia coli. (1992) (3)
- Crystallographic studies on the structure and function of glycogen phosphorylase b. (1978) (3)
- Professor Dorothy Hodgkin, OM, FRS (1994) (3)
- The binding of β-glycerophosphate to glycogen phosphorylase b in the crystal (1989) (3)
- From Structure to Therapy (1996) (3)
- The role of pyridoxal phosphate in glycogen phosphorylase b; structure, environment and relationship to catalytic mechanism. (1984) (3)
- Phosphate-recognition sites in catalysis and control of glycogen phosphorylase b. (1987) (3)
- Structural aspects of enzymatic activity A report of the british biophysical society meeting held in London on 17 and 18 December 1968 (1969) (3)
- David Phillips and the origin of structural enzymology. (1999) (3)
- Solid state 31P cross-polarization/magic angle sample spinning nuclear magnetic resonance of crystalline glycogen phosphorylase b. (1993) (2)
- Chapter 5 Protein crystallography (1985) (2)
- Following proteins in time (1990) (2)
- O-6-alkylguanines as selective inhibitors of cyclin dependent kinases (1998) (2)
- Structural and thermodynamic validation of inactive cdk2 as a template for structure-based drug design (2001) (2)
- Early days of Structural Biology (2008) (2)
- Specific Inhibition of Glycogen Phosphorylase by a Spirodiketopiperazine at the Anomeric Position of Glucopyranose. (2010) (1)
- Structure of human Thr160-phospho CDK2/cyclin A complexed with the inhibitor NU6102 (2002) (1)
- Professor Dorothy Hodgkin, OM, FRS. 1910-1994. (1994) (1)
- Cell Signalling Through Covalent Modification and Allostery (2012) (1)
- The structure of phospho-CDK2/cyclin A in complex with the inhibitor 4,5,6,7-tetrabromobenzotriazole (TBS) (2003) (1)
- Structural Characterization of a Prokaryotic Lipase (1996) (1)
- THE STRUCTURE OF GLYCOGEN PHOSPHORYLASE B WITH AN ALKYL-DIHYDROPYRIDINE-DICARBOXYLIC ACID (1997) (1)
- Crystal Structure of Human CDK7 (2004) (1)
- EM and X-ray studies of HupR, a response regulator from the NtrC family (2005) (1)
- The sequence around the phosphorylation site of the porcine heart type phosphorylase isoenzyme. (1988) (1)
- Antiproliferative cyclin dependent kinase inhibitors with distinct molecular interactions and tumor cell growth inhibition profiles. (1999) (1)
- Signal transduction proteins: Structural basis of control by phosphorylation (1999) (1)
- Flavopiridol binding to P-TEFb (CDK9/cyclin T1) (2008) (1)
- CDK2/CyclinA in complex with an 11-residue recruitment peptide from p107 (2003) (1)
- Potent Inhibition of Glycogen Phosphorylase by a Spirohydantoin of Glucopyranose: First Pyranose Analogues of Hydantocidin. (1995) (1)
- Analysis of the structure at 2 Å resolution (2012) (1)
- X-ray diffraction studies on enzyme catalysis and allosteric control of glycogen phosphorylase b (1989) (0)
- X-Ray and Solution Studies on Glycogen Phosphorylase Reconstituted with Pyridoxal in Place of the Natural Coenzyme (1991) (0)
- Glycoconjugates and recognition phenomena. (1983) (0)
- Catalysis and regulation Channels, terpenes and phosphates (1998) (0)
- Crystal structure of the HupR receiver domain in inhibitory phospho- state (2008) (0)
- Exploiting structural principles to generate protein kinase inhibitors (2005) (0)
- Structure based design of a potent inhibitor of CDK2 (2001) (0)
- PROTEIN KINASE STRUCTURE AND MECHANISM (1999) (0)
- The structural basis of CDK2 activation by cyclin E (2005) (0)
- Crystal structure of phospho-CDK2 in complex with Cyclin B (2007) (0)
- Protein Crystallography and Structure Based Drug Design (2000) (0)
- Glycogen Phosphorylase b (2020) (0)
- Protein kinase inhibition and substrate recognition (2005) (0)
- Novartis Medal Lecture The regulation of protein phosphorylation (2009) (0)
- Crystal Structure of the Maltodextrin Phosphorylase complexed with the products of the enzymatic reaction between glucose-1-phosphate and maltopentaose (2002) (0)
- Structure-based protein kinase inhibitor design (2006) (0)
- SPIROHYDANTOIN INHIBITOR OF GLYCOGEN PHOSPHORYLASE (1998) (0)
- Crystal structure of phospho-CDK2 Cyclin A in complex with a peptide containing both the substrate and recruitment sites of CDC6 (2006) (0)
- The open state of KirBac3.1 observed by cryo-electron microscopy (2007) (0)
- Expression of the γ-subunit of Phosphorylase b Kinase in Escherichia coli (1991) (0)
- PHOSPHORYLATED CDK2-CYCLYIN A-SUBSTRATE PEPTIDE COMPLEX (1999) (0)
- Noble , from Structure Protein Kinase Inhibitors : Insights into Drug Design (2007) (0)
- Glucose analogue inhibitors of glycogen phosphorylase: the design of potential drugs for diabetes (1993) (0)
- THE CRYSTAL STRUCTURE OF THE E. COLI MALTODEXTRIN PHOSPHORYLASE COMPLEX (1999) (0)
- The crystal structure of Escherichia coli maltodextrin phosphorylase provides an explanation for the activity without control in this basic archetype of a phosphorylase by maltose or maltodextrin induces expression of the other (2013) (0)
- 7‐Carbon Mimics of D‐Glucose and L‐Fucose: Activation by 6R‐, and Inactivation by 6S, ‐6C‐Methylglucose of Glycogen Synthase: Inhibition of Glucokinase and/or Glucose‐6‐phosphatase. (2010) (0)
- Design, synthesis, and biological evaluation of O-6-alkylguanine and O-4-alkylpyrimidine cyclin-dependent kinase inhibitors (2000) (0)
- The crystal structure of CDK2 cyclin A in complex with a substrate peptide derived from CDC modified with a gamma-linked ATP analogue (2006) (0)
- Crystal structure of the UBL domain of Dsk2 from S. cerevisiae (2006) (0)
- Crystallographic studies towards the catalytic mechanism of glycogen phosphorylase (1993) (0)
- Photoproduct of the wild-type Aequorea victoria Green Fluorescent Protein (2001) (0)
- HUMAN CYCLIN DEPENDENT KINASE 2 COMPLEXED WITH THE INHIBITOR NU6027 (2001) (0)
- The crystal structure of human CDK7 and its protein recognition properties (2005) (0)
- Recognition model for Cdk7-Cdk2 trans-phosphorylation (2007) (0)
- Inhibitors of glycogen phosphorylase: in search of an antidiabetic drug (1996) (0)
- The Role of the Pyridoxal Phosphate in Glycogen Phosphorylase b (1987) (0)
- CDk2/cyclinA in complex with DRB (2010) (0)
- Insights into CDK inhibitor design from X-ray crystallographic studies (1998) (0)
- Structure-activity relationships and cellular effects of novel purine- and pyrimidine-based cyclin dependent kinase inhibitors (2000) (0)
- Crystal Structure of Human CDK9/cyclinT1 (2008) (0)
- Human cyclin dependent protein kinase 2 in complex with the inhibitor 2-Amino-6-[(R)-pyrrolidino-5'-yl]methoxypurine (2003) (0)
- Structure of human Thr160-phospho CDK2/cyclin A complexed with the inhibitor NU6086 (2002) (0)
- Structure of human Thr160-phospho CDK2/cyclin A complexed with the inhibitor NU6094 (2002) (0)
- Obituary: David Phillips (1924—99) (1999) (0)
- Human cyclin dependent protein kinase 2 in complex with the inhibitor 2-Amino-6-[cyclohex-3-enyl]methoxypurine (2003) (0)
- HUMAN CYCLIN-DEPENDENT KINASE 2 (1998) (0)
- Protein kinase inhibition of CDK2 by staurosporine (1998) (0)
- Crystal structure of the D55E mutant of the HupR receiver domain (2008) (0)
- Protein oligosaccharide interactions: glycogen phosphorylase and lysozyme (1993) (0)
- Crystal Structure of the Maltodextrin Phosphorylase complexed with Glucose-1-phosphate (2002) (0)
- Binding of N-acetyl-beta-D-glucopyranosylamine to Glycogen Phosphorylase B (1998) (0)
- The structural basis for the modulation of protein function by protein phosphorylation (2010) (0)
- HUMAN CYCLIN DEPENDENT KINASE 2 COMPLEXED WITH THE INHIBITOR 2-Amino-6-(3'-methyl-2'-oxo)butoxypurine (2003) (0)
- BINDING OF 2-DEOXY-GLUCOSE-6-PHOSPHATE TO GLYCOGEN PHOSPHORYLASE B (1998) (0)
- Glycogen phosphorylase b: control and activity (1981) (0)
- Crystal Structure of Human CDK9/cyclinT1 in Complex with ATP (2008) (0)
- Spirohydantoins of Glucofuranose: Analogues of Hydantocidin. (1995) (0)
- PHOTOTRANSFORMATION OF THE WILD-TYPE AEQUOREA VICTORIA GREEN FLUORESCENT PROTEIN WITH UV-AND VISIBLE LIGHT LEADS TO DECARBOXYLATION OF GLUTAMATE 222 (2002) (0)
- Structure of human Thr160-phospho CDK2/cyclin A complexed with the inhibitor NU2058 (2002) (0)
- CRYSTAL STRUCTURE OF KINASE ASSOCIATED PHOSPHATASE (KAP) IN COMPLEX WITH PHOSPHO-CDK2 (2001) (0)
- pCDK2/cyclin A in complex with MgADP, nitrate and peptide substrate (2002) (0)
- AMIDOCARBAMATE INHIBITOR OF GLYCOGEN PHOSPHORYLASE (1998) (0)
- PHOSPHORYLASE B AND N-ACETYL-BETA-D-GLUCOPYRANOSYLAMINE-IMP COMPLEX (1995) (0)
- Stereospecific Synthesis of Spirohydantoins of β-Glucopyranose: Inhibitors of Glycogen Phosphorylase. (2010) (0)
- Contents (2015) (0)
- PHOSPHORYLASE B AND 2-DEOXY-GLUCOSE-6-PHOSPHATE COMPLEX (1995) (0)
- HUMAN CYCLIN DEPENDENT KINASE 2 COMPLEXED WITH THE INHIBITOR STAUROSPORINE (1997) (0)
- CDK2/Cyclin A in complex with an 11-residue recruitment peptide from retinoblastoma-associated protein (2003) (0)
- The crystal structure of N-acetyl-alpha-D-glucosamine. (1966) (0)
- Structures of glycogen phosphorylase-inhibitor complexes and the implications for structure-based drug design (2000) (0)
- The polo-box domain of Plk1 in complex with a phospho-peptide (2003) (0)
- Oligosaccharide binding to glycogen phosphorylase b. (1983) (0)
- HUMAN CYCLIN-DEPENDENT KINASE 2 PHOSPHORYLATED ON THR 160 (1998) (0)
- CRYSTALLOGRAPHY OF BIOLOGICAL MACROMOLECULES (2005) (0)
- Learning modern protein crystallography (1995) (0)
- Molecular recognition in the action of protein kinases: the basis for affinity and specificity (2000) (0)
- IDENTIFICATION AND STRUCTURAL CHARACTERIZATION OF A NOVEL ALLOSTERIC BINDING SITE OF GLYCOGEN PHOSPHORYLASE B (1999) (0)
- CRYSTAL STRUCTURE ANALYSIS OF KINASE ASSOCIATED PHOSPHATASE (KAP) WITH A SUBSTITUTION OF THE CATALYTIC SITE CYSTEINE (CYS140) TO A SERINE (2001) (0)
- α-Azidoesters as Divergent Intermediates for Combinatorial Generation of Glucofuranose Libraries of Novel N-Linked Glycopeptides. (2010) (0)
- Physics and biology: Applications of synchrotron radiation in biology (2008) (0)
- PYRIDOXAL PHOSPHORYLASE B IN COMPLEX WITH FLUOROPHOSPHATE, GLUCOSE AND INOSINE-5'-MONOPHOSPHATE (1997) (0)
- Glycoconjugates and recognition phenomena. (1983) (0)
- Solid state 3'P cross-polarization/magic angle sample spinning nuclear magnetic resonance studies of crystalline glycogen phosphorylase b (2005) (0)
- COMPLEX OF GLYCOGEN PHOSPHORYLASE WITH A TRANSITION STATE ANALOGUE NOJIRIMYCIN TETRAZOLE AND PHOSPHATE IN THE T STATE (1996) (0)
- HUMAN CYCLIN DEPENDENT KINASE 2 COMPLEXED WITH THE INHIBITOR NU2058 (2001) (0)
- Advances in Determination of Protein Structure by X-ray Diffraction Methods (1997) (0)
- Glycogen phosphorylase b: structure determination and refinement (1981) (0)
- Structure based drug design (1993) (0)
- Crystal structure of the Mud1 UBA domain (2005) (0)
- Crystal Structure of Human CDK9/cyclinT1 in complex with Flavopiridol (2008) (0)
- Structure of CDK9/cyclinT1 in complex with DRB (2010) (0)
- Introductory overview (1999) (0)
- Structural and functional studies of rabbit skeletal muscle Phosphorylase Kinase (2008) (0)
- THE CRYSTAL STRUCTURE OF UCN-01 IN COMPLEX WITH PHOSPHO-CDK2/CYCLIN A (2003) (0)
- The binding of beta-glycerophosphate to glycogen phosphorylase b in the crystal. (1989) (0)
- The crystal structure of the complex between the UBA and UBL domains of Dsk2 (2006) (0)
- 100 K STRUCTURE OF GLYCOGEN PHOSPHORYLASE AT 2.0 ANGSTROMS RESOLUTION (1998) (0)
- Crystal structure of the wild-type HupR receiver domain (2008) (0)
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