Louise Pearce
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Most Influential Person Across History
American pathologist
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Biology
Why Is Louise Pearce Influential?
(Suggest an Edit or Addition)According to Wikipedia, Louise Pearce was an American pathologist at the Rockefeller Institute who helped develop a treatment for African sleeping sickness . Sleeping sickness was a fatal epidemic which had devastated areas of Africa, killing two-thirds of the population of the Uganda protectorate between 1900 and 1906 alone. With chemists Walter Abraham Jacobs and Michael Heidelberger and pathologist Wade Hampton Brown, Pearce worked to develop and test arsenic-based drugs for its treatment. In 1920, Louise Pearce traveled to the Belgian Congo where she designed and carried out a drug testing protocol for human trials to establish tryparsamide's safety, effectiveness, and optimum dosage. Tryparsamide proved successful in combating the fatal epidemic, curing 80% of cases.
Louise Pearce's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- HEREDITARY ACHONDROPLASIA IN THE RABBIT : I. PHYSICAL APPEARANCE AND GENERAL FEATURES. (1945) (42)
- GROWTH AND PERSISTENCE OF FILTERABLE VIRUSES IN A TRANSPLANTABLE RABBIT NEOPLASM (1925) (37)
- HEREDITARY OSTEOPETROSIS OF THE RABBIT I. GENERAL FEATURES AND COURSE OF DISEASE; GENETIC ASPECTS (1948) (36)
- STUDIES BASED ON A MALIGNANT TUMOR OF THE RABBIT (1923) (29)
- HEREDITARY OSTEOPETROSIS OF THE RABBIT II. X-RAY, HEMATOLOGIC, AND CHEMICAL OBSERVATIONS (1948) (27)
- HEREDITARY OSTEOPETROSIS OF THE RABBIT IV. PATHOLOGIC OBSERVATIONS; GENERAL FEATURES (1950) (25)
- HEREDITARY ACHONDROPLASIA IN THE RABBIT II. PATHOLOGIC ASPECTS (1945) (25)
- STUDIES ON THE TREATMENT OF HUMAN TRYPANOSOMIASIS WITH TRYPARSAMIDE (THE SODIUM SALT OF N-PHENYLGLYCINEAMIDE-p-ARSONIC ACID) (1921) (24)
- Hereditary osteopetrosis of the rabbit. III. Pathologic observations; skeletal abnormalities. (1950) (24)
- HEREDITARY ACHONDROPLASIA IN THE RABBIT : III. GENETIC ASPECTS; GENERAL CONSIDERATIONS (1945) (23)
- ORGAN WEIGHTS OF NORMAL RABBITS (1925) (22)
- STUDIES BASED ON A MALIGNANT TUMOR OF THE RABBIT (1923) (21)
- A STUDY OF THE RELATION OF TREPONEMA PALLIDUM TO LYMPHOID TISSUES IN EXPERIMENTAL SYPHILIS (1921) (21)
- Miller Fisher Syndrome (Variant of Landry-Guillain-Barre-Strohl Syndrome—Ophthalmoplegia, Ataxia, Areflexia) (1966) (18)
- A NOTE ON THE DISSEMINATION OF SPIROCHAETA PALLIDA FROM THE PRIMARY FOCUS OF INFECTION (1920) (17)
- STUDIES BASED ON A MALIGNANT TUMOR OF THE RABBIT (1923) (17)
- STUDIES BASED ON A MALIGNANT TUMOR OF THE RABBIT (1923) (17)
- STUDIES BASED ON A MALIGNANT TUMOR OF THE RABBIT (1923) (16)
- EXPERIMENTAL SYPHILIS IN THE RABBIT : I. PRIMARY INFECTION IN THE TESTICLE. (1920) (16)
- MELANOMA (SARCOMA) OF THE EYE IN A SYPHILITIC RABBIT (1926) (14)
- SUPERINFECTION IN EXPERIMENTAL SYPHILIS FOLLOWING THE ADMINISTRATION OF SUBCURATIVE DOSES OF ARSPHENAMINE OR NEOARSPHENAMINE (1921) (14)
- STUDIES ON THE ETIOLOGY OF RABBIT POX III. TESTS OF THE RELATION OF RABBIT POX VIRUS TO OTHER VIRUSES BY CROSSED INOCULATION AND EXPOSURE EXPERIMENTS (1936) (12)
- HEREDITARY DISTAL FORELEG CURVATURE IN THE RABBIT (1960) (12)
- DISTINCTIVE CHARACTERISTICS OF INFECTIONS PRODUCED BY TREPONEMA PERTENUE IN THE RABBIT (1925) (12)
- Hereditary premature sensescence of the rabbit. I. Chronic form; general features. (1960) (12)
- EXPERIMENTAL SYPHILIS IN THE RABBIT : VII. AFFECTIONS OF THE EYES. (1921) (11)
- CHEMOTHERAPY OF TRYPANOSOME AND SPIROCHETE INFECTIONS BIOLOGICAL SERIES. I. THE TOXIC ACTION OF N-PHENYLGLYCINEAMIDE-p-ARSONIC ACID. (1919) (11)
- EXPERIMENTAL PRODUCTION OF CLINICAL TYPES OF SYPHILIS IN THE RABBIT (1921) (11)
- STUDIES ON THE ETIOLOGY OF RABBIT POX : I. ISOLATION OF A FILTERABLE AGENT: ITS PATHOGENIC PROPERTIES. (1936) (11)
- STUDIES IN THE BLOOD CYTOLOGY OF THE RABBIT (1930) (11)
- Hereditary premature senescence of the rabbit. II. Acute form; general features. (1960) (10)
- HEREDITARY VARIATIONS IN THE BLOOD CYTOLOGY OF NORMAL RABBITS. (1934) (10)
- STUDIES BASED ON A MALIGNANT TUMOR OF THE RABBIT (1923) (10)
- ORGAN WEIGHTS OF NORMAL RABBITS : SECOND PAPER. (1926) (10)
- EXPERIMENTAL SYPHILIS IN THE RABBIT II. PRIMARY INFECTION IN THE SCROTUM. PART 2. SCROTAL LESIONS AND THE CHARACTER OF THE SCROTAL INFECTION. (1920) (10)
- Hereditary distal foreleg curvature in the rabbit. II. Genetic and pathological aspects. (1960) (9)
- KLOSSIELLA INFECTION OF THE GUINEA PIG (1916) (9)
- A COMPARISON OF ADULT AND INFANT TYPES OF GONOCOCCI (1915) (9)
- TRYPARSAMIDE: ITS ACTION AND USE (1924) (9)
- EFFECT OF HOST IMMUNITY TO A FILTERABLE VIRUS (VIRUS III) ON THE GROWTH AND MALIGNANCY OF A TRANSPLANTABLE RABBIT NEOPLASM (1927) (9)
- THE HEMOCYTOLOGICAL CONSTITUTION OF ADULT MALE RABBITS FROM FIFTEEN STANDARD BREEDS (1936) (9)
- CHEMOPATHOLOGICAL STUDIES WITH COMPOUNDS OF ARSENIC II. HISTOLOGICAL CHANGES IN ARSENIC KIDNEYS. (1915) (8)
- EXPERIMENTAL SYPHILIS IN THE RABBIT : VI. AFFECTIONS OF BONE, CARTILAGE, TENDONS, AND SYNOVIAL MEMBRANES. PART 1. LESIONS OF THE SKELETAL SYSTEM. (1921) (8)
- STUDIES ON THE ETIOLOGY OF RABBIT POX (1936) (8)
- THE BLOOD CYTOLOGY IN UNTREATED AND TREATED SYPHILIS (1934) (8)
- CHEMOPATHOLOGICAL STUDIES WITH COMPOUNDS OF ARSENIC III. ON THE PATHOLOGICAL ACTION OF ARSENICALS ON THE ADRENALS. (1915) (8)
- HEREDITARY OSTEOPETROSIS OF THE RABBIT (1950) (8)
- STUDIES BASED ON A MALIGNANT TUMOR OF THE RABBIT : V. METASTASES. PART 1. DESCRIPTION OF THE LESIONS WITH ESPECIAL REFERENCE TO THEIR OCCURRENCE AND DISTRIBUTION. (1923) (8)
- COMPARISON OF THE HEMACYTOLOGICAL CONSTITUTION OF MALE AND FEMALE RABBITS (1934) (8)
- RECIPROCAL EFFECTS OF CONCOMITANT INFECTIONS : III. THE INFLUENCE OF VACCINIA AND OF VACCINAL IMMUNITY ON THE REACTION TO INFECTION WITH EXPERIMENTAL SYPHILIS (INTRACUTANEOUS INOCULATION). (1928) (8)
- INFLUENCE OF LIGHT ON THE GROWTH AND MALIGNANCY OF A TRANSPLANTABLE NEOPLASM OF THE RABBIT (1927) (7)
- HEREDITARY ACHONDROPLASIA IN THE RABBIT (1945) (7)
- CHEMOTHERAPY OF TRYPANOSOME AND SPIROCHETE INFECTIONS : BIOLOGICAL SERIES. II. THE THERAPEUTIC ACTION OF N-PHENYLGLYCINEAMIDE-p-ARSONIC ACID IN EXPERIMENTAL TRYPANOSOMIASIS OF MICE, RATS, AND GUINEA PIGS. (1919) (7)
- STUDIES ON THE ETIOLOGY OF RABBIT POX : IV. TESTS ON THE RELATION OF RABBIT POX VIRUS TO OTHER VIRUSES BY SERUM NEUTRALIZATION EXPERIMENTS. (1936) (7)
- Experimental Transmission of Rabbit-Pox by a Filterable Virus (1933) (7)
- RECIPROCAL EFFECTS OF CONCOMITANT INFECTIONS : I. THE INFLUENCE OF VACCINIA ON THE REACTION TO INFECTION WITH EXPERIMENTAL SYPHILIS. (1928) (6)
- THE EFFECT OF OPERATIVE INTERFERENCE WITH THE CERVICAL SYMPATHETIC NERVOUS SYSTEM UPON THE GROWTH AND MALIGNANCY OF A TRANSPLANTABLE NEOPLASM OF THE RABBIT (1925) (6)
- EXPERIMENTAL SYPHILIS IN THE RABBIT : IV. CUTANEOUS SYPHILIS. PART 1. AFFECTIONS OF THE SKIN AND APPENDAGES. (1920) (6)
- Animal resistance and the endocrine system of the rabbit in experimental syphilis (1923) (6)
- STUDIES BASED ON A MALIGNANT TUMOR OF THE RABBIT (1923) (6)
- EXPERIMENTAL SYPHILIS IN THE RABBIT (1920) (6)
- CHEMOTHERAPY OF TRYPANOSOME AND SPIROCHETE INFECTIONS (1919) (6)
- The Reaction of Normal and Rabbit Pox Immune Adult Rabbits to Vaccination with Vaccine Virus (1936) (6)
- STUDIES IN THE BLOOD CYTOLOGY OF THE RABBIT (1930) (5)
- THE INFLUENCE OF LIGHT ON THE REACTION TO INFECTION IN EXPERIMENTAL SYPHILIS (1927) (5)
- EXPERIMENTAL TRYPANOSOMIASIS: ITS APPLICATION IN CHEMOTHERAPEUTIC INVESTIGATIONS (1918) (5)
- STUDIES ON THE ETIOLOGY OF RABBIT POX : V. STUDIES ON SPECIES SUSCEPTIBILITY TO RABBIT POX VIRUS. (1936) (5)
- STUDIES BASED ON A MALIGNANT TUMOR OF THE RABBIT (1923) (5)
- EXPERIMENTAL SYPHILIS IN THE RABBIT (1921) (5)
- EXPERIMENTAL SYPHILIS IN THE RABBIT IV. CUTANEOUS SYPHILIS. PART 2. CLINICAL ASPECTS OF CUTANEOUS SYPHILIS. (1920) (5)
- PENETRATION OF NORMAL MUCOUS MEMBRANES OF THE RABBIT BY TREPONEMA PALLIDUM AND THE INFLUENCE OF THIS MODE OF INFECTION UPON THE COURSE OF THE DISEASE (1924) (5)
- THERAPEUTIC ACTION OF N-PHENYLGLYCINEAMIDE-p-ARSONIC ACID (TRYPARSAMIDE) UPON EXPERIMENTAL INFECTIONS OF TRYPANOSOMA RHODESIENSE (1921) (5)
- THE RELATION BETWEEN BODY AND ORGAN WEIGHTS IN THE RABBIT (1926) (4)
- STUDIES BASED ON A MALIGNANT TUMOR OF THE RABBIT (1923) (4)
- CHEMOTHERAPY OF TRYPANOSOME AND SPIROCHETE INFECTIONS BIOLOGICAL SERIES. IV. THE ACTION OF N-PHENYLGLYCINEAMIDE-p-ARSONIC ACID UPON SPIROCHETE INFECTIONS. (1919) (4)
- RECIPROCAL EFFECTS OF CONCOMITANT INFECTIONS : II. THE INFLUENCE OF VACCINAL IMMUNITY ON THE REACTION TO EXPERIMENTAL SYPHILIS. (1928) (4)
- Positive Wassermann Reaction Induced in Rabbits by Injection of Hamster Tissues.∗ (1935) (4)
- STUDIES ON THE ETIOLOGY OF RABBIT POX (1936) (4)
- Failure to demonstrate Spirochaeta pallida in Cerebrospinal Fluid of Syphilitic Chinese Patients. (1936) (4)
- THE OCCURRENCE OF STIGMATA OF CONGENITAL SYPHILIS IN RABBITS WITH ESPECIAL REFERENCE TO THE FACTOR OF INHERITANCE (1925) (4)
- Neoplasia in experimental syphilis (1921) (4)
- THE OCCURRENCE AND TREND OF SPONTANEOUS VARIATIONS IN ORGAN WEIGHTS OF NORMAL RABBITS (1926) (4)
- SYPHILITIC INFECTION OF THE CENTRAL NERVOUS SYSTEM OF THE RABBIT (1920) (4)
- THE RESISTANCE (OR IMMUNITY) DEVELOPED BY THE REACTION TO SYPHILITIC INFECTION: AND SOME OF THE EFFECTS OF THE SUPPRESSION OF THIS REACTION (1920) (4)
- TRYPARSAMIDE TREATMENT OF AFRICAN SLEEPING SICKNESS. (1925) (3)
- EFFECTS OF SPONTANEOUS DISEASE ON ORGAN WEIGHTS OF RABBITS (1926) (3)
- NOTE ON THE PRESERVATION OF STOCK STRAINS OF TREPONEMA PALLIDUM AND ON THE DEMONSTRATION OF INFECTION IN RABBITS (1921) (3)
- EFFECT OF A FILTERABLE VIRUS (VIRUS III) ON THE GROWTH AND MALIGNANCY OF A TRANSPLANTABLE NEOPLASM OF THE RABBIT (1927) (3)
- Seasonal changes in organ weights and their relation to meteorological conditions. (1924) (3)
- CHEMOPATHOLOGICAL STUDIES WITH COMPOUNDS OF ARSENIC : I. TYPES OF THE ARSENIC KIDNEY. (1915) (3)
- FURTHER OBSERVATIONS ON THE INABILITY TO TRANSMIT A RABBIT NEOPLASM BY CELL-FREE MATERIALS (1927) (3)
- Effects of sunlight on the malignancy of a transplanted tumor of the rabbit. (1924) (3)
- Reciprocal Influence of Concomitant Infections (1927) (3)
- The Cellular Reaction in Experimental Syphilis. Supravital and Fixed Material. (1931) (3)
- EXPERIMENTAL SYPHILIS IN THE RABBIT (1920) (3)
- STUDIES IN THE BLOOD CYTOLOGY OF THE RABBIT (1930) (2)
- EXPERIMENTAL SYPHILIS IN THE RABBIT : VI. AFFECTIONS OF BONE, CARTILAGE, TENDONS, AND SYNOVIAL MEMBRANES. PART 2. CLINICAL ASPECTS OF SYPHILIS OF THE SKELETAL SYSTEM. AFFECTIONS OF THE FACIAL AND CRANIAL BONES AND THE BONES OF THE FOREARM. (1921) (2)
- EXPERIMENTAL SYPHILIS IN THE RABBIT (1920) (2)
- EFFECTS OF OBSCURE LESIONS ON ORGAN WEIGHTS OF APPARENTLY NORMAL RABBITS (1925) (2)
- STUDIES IN THE BLOOD CYTOLOGY OF THE RABBIT (1930) (2)
- Operative results of thyroidectomy and thymectomy in the rabbit. (1924) (2)
- SYPHILITIC MYOCARDITIS IN THE RABBIT (1926) (2)
- The reaction of the endocrine system of the rabbit to tumor inoculation and the relation of this reaction to malignancy (1923) (2)
- HEREDITARY ACHONDROPLASIA IN THE RABBIT (1945) (2)
- HEREDITARY PREMATURE SENESCENCE OF THE RABBIT (1960) (2)
- On the generalization of treponema pallidum in the rabbit following local inoculation (1920) (2)
- EFFECT OF THYROIDECTOMY AND OF THYMECTOMY IN EXPERIMENTAL SYPHILIS OF THE RABBIT (1926) (2)
- STUDIES IN THE BLOOD CYTOLOGY OF THE RABBIT (1930) (2)
- Superinoculation experiments with Treponema pallidum (1921) (2)
- HEREDITARY PREMATURE SENESCENCE OF THE RABBIT (1960) (2)
- HEREDITARY DISTAL FORELEG CURVATURE IN THE RABBIT (1960) (2)
- EFFECTS OF LIGHT ON NORMAL RABBITS, WITH ESPECIAL REFERENCE TO THE ORGANIC REACTION (1926) (2)
- The Reaction of the Nursling Rabbit to Vaccination with Vaccine Virus (1936) (2)
- EXPERIMENTAL SYPHILIS OF ORIENTAL ORIGIN: CLINICAL REACTION IN THE RABBIT (1938) (2)
- Susceptibility of the Chinese Stripted Hamster (Cricetulus Grisens) to Treponema pallidum (1932) (2)
- Epidemiological Aspects of Spontaneously Acquired Vaccinia in the Rabbit. (1936) (2)
- THERAPEUTIC ACTION OF POTASSIUM IODID IN EXPERIMENTAL SYPHILIS OF THE RABBIT (1925) (2)
- CHEMOTHERAPY OF TRYPANOSOME AND SPIROCHETE INFECTIONS (1919) (1)
- STUDIES IN THE BLOOD CYTOLOGY OF THE RABBIT (1930) (1)
- RELATION BETWEEN ORGAN WEIGHTS AND OBSCURE LESIONS IN APPARENTLY NORMAL RABBITS (1926) (1)
- Reaction of the Rabbit to Vaccine Virus (1934) (1)
- The penetration of normal mucous membranes of the rabbit by Treponema pallidum (1921) (1)
- HEREDITARY OSTEOPETROSIS OF THE RABBIT (1948) (1)
- Effect of controlled conditions of illumination upon malignancy of transplantable neoplasm. (1925) (1)
- Comparison of the Blood Picture in Treated and Untreated Syphilis Patients (1932) (1)
- CHEMOPATHOLOGICAL STUDIES WITH COMPOUNDS OF ARSENIC : IV. THE CHARACTER AND DISTRIBUTION OF RENAL INJURY PRODUCED BY ARSENICALS AS INDICATED BY THE PROCESSES OF REPAIR. (1916) (1)
- EFFECTS OF LIGHT ON NORMAL RABBITS, WITH ESPECIAL REFERENCE TO THE ORGANIC REACTION (1926) (1)
- EXPERIMENTAL SYPHILIS IN THE RABBIT (1920) (1)
- Monocytosis and Lymphopenia in Experimental Rabbit-Pox (1933) (1)
- EXPERIMENTAL SYPHILIS IN THE RABBIT (1921) (1)
- The Association of Blood Cell Factors with the Transplantability of the Brown-Pearce Tumor (1942) (1)
- INFLUENCE OF LIGHT ON THE GROWTH AND MALIGNANCY OF A TRANSPLANTABLE NEOPLASM OF THE RABBIT (1927) (1)
- On the Pathological Action oe Arsenicals Upon the Adrenals. (1915) (1)
- STUDIES ON THE BLOOD CYTOLOGY OF THE RABBIT (1931) (1)
- Ii. Histological Changes in Arsenic Kidneys (0)
- The Toxic Action O1~ N-phenylglycineamide-p-aesonic Acre (0)
- OBSERVATIONS ON THE BLOOD CYTOLOGY IN EXPERIMENTAL SYPHILIS (1934) (0)
- 474 EXPERIMENTAL SYPHILIS IN THE RABBIT (0)
- Chicago Laryngological and Otological Society in Joint Meeting with Chicago Ophthalmological Society (1925) (0)
- CHEMOTHERAPY OF TRYPANOSOME AND SPIROCHETE INFECTIONS (1919) (0)
- CHEMOPATHOLOGICAL STUDIES WITH COMPOUNDS OF ARSENIC (1916) (0)
- EXPERIMENTAL SYPHILIS IN THE RABBIT (1920) (0)
- STUDIES ON THE TREATMENT OF HUMAN TRYPANOSOMIASIS WITH TRYPARSAMIDE (THE SODIUM SALT OF N-PHENYLGLYCINEAMIDE-p-ARSONIC ACID) (1922) (0)
- STUDIES ON THE ETIOLOGY OF RABBIT POX (1936) (0)
- EXPERIMENTAL SYPHILIS IN THE RABBIT (1921) (0)
- Letter from Louise Pearce to Michael Heidelberger (1920) (0)
- METHODS AND MATERIAL (1964) (0)
- EFFECTS OF LIGHT ON NORMAL RABBITS, WITH ESPECIAL REFERENCE TO THE ORGANIC REACTION (1926) (0)
- Variations in the Character and Distribution of the Renal Lesions Produced by Compounds of Arsenic. (1915) (0)
- CHEMOPATHOLOGICAL STUDIES WITH COMPOUNDS OF ARSENIC (1915) (0)
- EXPERIMENTAL SYPHILIS IN THE RABBIT (1920) (0)
- HEREDITARY ACHONDROPLASIA IN THE RABBIT (1945) (0)
- The Monocytic Reaction in Neoplasia of the Rabbit. (1929) (0)
- RECIPROCAL EFFECTS OF CONCOMITANT INFECTIONS (1928) (0)
- CHEMOPATHOLOGICAL STUDIES WITH COMPOUNDS OF ARSENIC (1915) (0)
- The Monocytic Reaction in Virus III Disease. (1929) (0)
- TRYPARSAMIDE IN THE CONTROL OF AFRICAN SLEEPING SICKNESS. (1939) (0)
- EXPERIMENTAL SYPHILIS IN THE RABBIT (1921) (0)
- The Treatment of Human Trypanosomiases with Tryparsamide. (0)
- Tryparsamide Treatment of African Sleeping Sickness (1925) (0)
- HEREDITARY OSTEOPETROSIS OF THE RABBIT (1948) (0)
- HEREDITARY OSTEOPETROSIS OF THE RABBIT (1950) (0)
- Multiple infections with Treponema pallidum in the rabbit (1921) (0)
- CHEMOTHERAPY OF TRYPANOSOME AND SPIROCHETE INFECTIONS (1919) (0)
- Blood Cell Factors in the Metastasis of the Brown-Pearce Tumor (1942) (0)
- RECIPROCAL EFFECTS OF CONCOMITANT INFECTIONS (1928) (0)
- INTRATHECAL INJECTIONS OF TRYPARSAMIDE (1923) (0)
- The Treatment of Human Trypanosomiasis with Tryparsamide. A Critical Review. (0)
- ORGAN WEIGHTS OF NORMAL RABBITS (1925) (0)
- On the production of generalized syphilis in the rabbit by local inoculation (1920) (0)
- CHEMOPATHOLOGICAL STUDIES WITH COMPOUNDS OF ARSENIC (1915) (0)
- RECIPROCAL EFFECTS OF CONCOMITANT INFECTIONS (1928) (0)
- EXPERIMENTAL SYPHILIS IN THE RABBIT (1920) (0)
- STUDIES ON THE ETIOLOGY OF RABBIT POX (1936) (0)
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What Schools Are Affiliated With Louise Pearce?
Louise Pearce is affiliated with the following schools:
