Luciano Marraffini
#45,110
Most Influential Person Now
Argentinian-American microbiologist
Luciano Marraffini's AcademicInfluence.com Rankings
Luciano Marraffinibiology Degrees
Biology
#2269
World Rank
#3626
Historical Rank
Microbiology
#495
World Rank
#556
Historical Rank
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Biology
Luciano Marraffini's Degrees
- PhD Microbiology University of Buenos Aires
Why Is Luciano Marraffini Influential?
(Suggest an Edit or Addition)According to Wikipedia, Luciano Marraffini is an Argentinian-American microbiologist. He is currently professor and head of the laboratory of bacteriology at The Rockefeller University. He is recognized for his work on CRISPR-Cas systems, being one of the first scientists to elucidate how these systems work at the molecular level.
Luciano Marraffini's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Multiplex Genome Engineering Using CRISPR/Cas Systems (2013) (12363)
- DNA targeting specificity of RNA-guided Cas9 nucleases (2013) (3909)
- RNA-guided editing of bacterial genomes using CRISPR-Cas systems (2013) (1886)
- CRISPR Interference Limits Horizontal Gene Transfer in Staphylococci by Targeting DNA (2008) (1501)
- CRISPR interference: RNA-directed adaptive immunity in bacteria and archaea (2010) (928)
- Programmable repression and activation of bacterial gene expression using an engineered CRISPR-Cas system (2013) (904)
- Sortases and the Art of Anchoring Proteins to the Envelopes of Gram-Positive Bacteria (2006) (656)
- CRISPR-Cas immunity in prokaryotes (2015) (610)
- CRISPR-Cas systems: Prokaryotes upgrade to adaptive immunity. (2014) (588)
- Exploiting CRISPR-Cas nucleases to produce sequence-specific antimicrobials (2014) (442)
- Self vs. non-self discrimination during CRISPR RNA-directed immunity (2009) (427)
- Co-transcriptional DNA and RNA Cleavage during Type III CRISPR-Cas Immunity (2015) (318)
- CRISPR-assisted editing of bacterial genomes (2013) (312)
- Cas9 specifies functional viral targets during CRISPR-Cas adaptation (2015) (306)
- Type III CRISPR–Cas systems produce cyclic oligoadenylate second messengers (2017) (295)
- CRISPR interference can prevent natural transformation and virulence acquisition during in vivo bacterial infection. (2012) (277)
- Protein sorting to the cell wall envelope of Gram-positive bacteria. (2004) (267)
- Conditional tolerance of temperate phages via transcription-dependent CRISPR-Cas targeting (2014) (243)
- Development of sequence-specific antimicrobials based on programmable CRISPR-Cas nucleases (2014) (235)
- Mature clustered, regularly interspaced, short palindromic repeats RNA (crRNA) length is measured by a ruler mechanism anchored at the precursor processing site (2011) (209)
- Dealing with the Evolutionary Downside of CRISPR Immunity: Bacteria and Beneficial Plasmids (2013) (200)
- Sortases and pilin elements involved in pilus assembly of Corynebacterium diphtheriae (2004) (192)
- Degradation of Phage Transcripts by CRISPR-Associated RNases Enables Type III CRISPR-Cas Immunity (2016) (168)
- CRISPR-Cas: New Tools for Genetic Manipulations from Bacterial Immunity Systems. (2015) (162)
- Molecular mechanisms of CRISPR–Cas spacer acquisition (2018) (152)
- Cas13-induced cellular dormancy prevents the rise of CRISPR-resistant bacteriophage (2019) (150)
- (Ph)ighting Phages: How Bacteria Resist Their Parasites. (2019) (143)
- Anchoring of Surface Proteins to the Cell Wall of Staphylococcus aureus (2004) (143)
- Genetic Characterization of Antiplasmid Immunity through a Type III-A CRISPR-Cas System (2013) (131)
- CRISPR-Cas systems exploit viral DNA injection to establish and maintain adaptive immunity (2017) (112)
- A High-Throughput Platform to Identify Small-Molecule Inhibitors of CRISPR-Cas9 (2019) (111)
- A Ruler Protein in a Complex for Antiviral Defense Determines the Length of Small Interfering CRISPR RNAs (2013) (110)
- Targeting proteins to the cell wall of sporulating Bacillus anthracis (2006) (104)
- Broad Targeting Specificity during Bacterial Type III CRISPR-Cas Immunity Constrains Viral Escape. (2017) (102)
- Assembly of pili on the surface of Bacillus cereus vegetative cells (2007) (100)
- Innate and adaptive immunity in bacteria: mechanisms of programmed genetic variation to fight bacteriophages. (2012) (98)
- Non-specific degradation of transcripts promotes plasmid clearance during type III-A CRISPR-Cas immunity (2018) (92)
- Adapting to new threats: the generation of memory by CRISPR‐Cas immune systems (2014) (90)
- Amide bonds assemble pili on the surface of bacilli (2008) (85)
- Enhanced Bacterial Immunity and Mammalian Genome Editing via RNA-Polymerase-Mediated Dislodging of Cas9 from Double-Strand DNA Breaks. (2018) (84)
- Bacillus anthracis Sortase A (SrtA) Anchors LPXTG Motif-Containing Surface Proteins to the Cell Wall Envelope (2005) (81)
- CRISPR-Cas Systems Optimize Their Immune Response by Specifying the Site of Spacer Integration. (2016) (80)
- Faculty Opinions recommendation of HORMA Domain Proteins and a Trip13-like ATPase Regulate Bacterial cGAS-like Enzymes to Mediate Bacteriophage Immunity. (2020) (70)
- Type III-A CRISPR-Cas Csm Complexes: Assembly, Periodic RNA Cleavage, DNase Activity Regulation, and Autoimmunity. (2019) (66)
- A phage-encoded anti-CRISPR enables complete evasion of type VI-A CRISPR-Cas immunity (2020) (61)
- Harnessing CRISPR-Cas9 immunity for genetic engineering. (2014) (60)
- Impact of CRISPR immunity on the emergence and virulence of bacterial pathogens. (2014) (58)
- RNA Guide Complementarity Prevents Self-Targeting in Type VI CRISPR Systems. (2018) (56)
- Molecular Mechanisms of CRISPR-Cas Immunity in Bacteria. (2020) (55)
- Anchor Structure of Staphylococcal Surface Proteins (2005) (54)
- Type III CRISPR-Cas systems: when DNA cleavage just isn't enough. (2017) (52)
- Control of gene expression by CRISPR-Cas systems (2013) (52)
- Activation and self-inactivation mechanisms of the cyclic oligoadenylate-dependent CRISPR ribonuclease Csm6 (2020) (51)
- The Card1 nuclease provides defence during Type III CRISPR immunity (2021) (46)
- Mutations in Cas9 Enhance the Rate of Acquisition of Viral Spacer Sequences during the CRISPR-Cas Immune Response. (2017) (43)
- Impact of Different Target Sequences on Type III CRISPR-Cas Immunity (2016) (41)
- Cas9 Cleavage of Viral Genomes Primes the Acquisition of New Immunological Memories. (2019) (40)
- A new antibiotic kills pathogens without detectable resistance (2015) (40)
- Sortase C-Mediated Anchoring of BasI to the Cell Wall Envelope of Bacillus anthracis (2007) (37)
- Dynamics of Cas10 Govern Discrimination between Self and Non-self in Type III CRISPR-Cas Immunity. (2019) (37)
- Recombination between phages and CRISPR-cas loci facilitates horizontal gene transfer in staphylococci (2019) (36)
- CRISPR-Cas Immunity against Phages: Its Effects on the Evolution and Survival of Bacterial Pathogens (2013) (35)
- Invasive DNA, chopped and in the CRISPR. (2009) (34)
- Resistance and tolerance to foreign elements by prokaryotic immune systems — curating the genome (2015) (34)
- Incomplete prophage tolerance by type III-A CRISPR-Cas systems reduces the fitness of lysogenic hosts (2018) (31)
- Co-evolution within structured bacterial communities results in multiple expansion of CRISPR loci and enhanced immunity (2020) (24)
- Enhanced bacterial immunity and mammalian genome editing via RNA polymerase-mediated dislodging of Cas9 from double strand DNA breaks (2018) (23)
- The CRISPR-Cas system of Streptococcus pyogenes: function and applications (2016) (23)
- Type III-A CRISPR immunity promotes mutagenesis of staphylococci (2021) (23)
- Three New Cs for CRISPR: Collateral, Communicate, Cooperate. (2019) (23)
- Microbiology: Slicer for DNA (2010) (21)
- Spacer Acquisition Rates Determine the Immunological Diversity of the Type II CRISPR-Cas Immune Response. (2019) (18)
- Prophage integration into CRISPR loci enables evasion of antiviral immunity in Streptococcus pyogenes (2021) (14)
- Impact of CRIPSR immunity on the emergence of bacterial pathogens. (2010) (12)
- Staphylococcal Sortases and Surface Proteins (2006) (12)
- Cleavage of viral DNA by restriction endonucleases stimulates the type II CRISPR-Cas immune response. (2022) (10)
- Sensing danger (2016) (9)
- Dynamics of Cas10 Govern Discrimination between Self and Nonself in Type III CRISPR-Cas Immunity (2018) (7)
- A CRISPR-Cas9–integrase complex generates precise DNA fragments for genome integration (2021) (7)
- Viral recombination systems limit CRISPR-Cas targeting through the generation of escape mutations. (2021) (6)
- Transfer in Staphylococci by Targeting DNA CRISPR Interference Limits Horizontal Gene (2009) (6)
- Viral Teamwork Pushes CRISPR to the Breaking Point (2018) (5)
- Different modes of spacer acquisition by the Staphylococcus epidermidis type III-A CRISPR-Cas system (2022) (3)
- Type III CRISPR-Cas systems generate cyclic oligoadenylate second messengers to activate Csm6 RNases (2017) (3)
- Faculty Opinions recommendation of Transposon-encoded CRISPR-Cas systems direct RNA-guided DNA integration. (2019) (2)
- From the discovery of DNA to current tools for DNA editing (2021) (2)
- Integration of prophages into CRISPR loci remodels viral immunity in Streptococcus pyogenes (2020) (2)
- Faculty Opinions recommendation of A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity. (2013) (2)
- Crispr‐Cas, The Prokaryotic Adaptive Immune System (2016) (2)
- Type III CRISPR-Cas Systems and the Roles of CRISPR-Cas in Bacterial Virulence (2013) (2)
- Cryo-EM structure of Cas13(crRNA) (2020) (1)
- Bacterial cGAS senses a viral RNA to initiate immunity (2023) (1)
- Expansion of CRISPR loci with multiple memories of infection enables the survival of structured bacterial communities (2019) (1)
- Mobile DNA: an evolving field (2014) (1)
- If You'd Like to Stop a Type III CRISPR Ribonuclease, Then You Should Put a Ring (Nuclease) on It. (2018) (1)
- Major Insights into Microbiology: An Interview with Luciano Marraffini. (2020) (1)
- Author response: Co-evolution within structured bacterial communities results in multiple expansion of CRISPR loci and enhanced immunity (2020) (1)
- Faculty of 1000 evaluation for A major lineage of non-tailed dsDNA viruses as unrecognized killers of marine bacteria. (2018) (0)
- Shoot the Messenger! A New Phage Weapon to Neutralize the Type III CRISPR Immune Response. (2020) (0)
- Faculty Opinions recommendation of Evolution and classification of the CRISPR-Cas systems. (2013) (0)
- CRISPR-assisted transposition: TnsC finds (and threads) the needle in the haystack. (2022) (0)
- Cas13-induced cellular dormancy prevents the rise of CRISPR-resistant bacteriophage (2019) (0)
- Faculty Opinions recommendation of An anti-CRISPR protein disables type V Cas12a by acetylation. (2019) (0)
- Faculty Opinions recommendation of sRNA-Mediated Control of Transcription Termination in E. coli. (2016) (0)
- Faculty Opinions recommendation of Antiviral activity of bacterial TIR domains via immune signalling molecules. (2021) (0)
- Decision letter: A chimeric nuclease substitutes a phage CRISPR-Cas system to provide sequence-specific immunity against subviral parasites (2021) (0)
- Breaking Down Walls (2016) (0)
- Cryo-EM structure of AcrVIA1-Cas13(crRNA) complex (2020) (0)
- Mobile DNA: an evolving field (2014) (0)
- Faculty Opinions recommendation of A Host-Produced Quorum-Sensing Autoinducer Controls a Phage Lysis-Lysogeny Decision. (2019) (0)
- CRISPR goes retro (2016) (0)
- Faculty Opinions recommendation of Small CRISPR RNAs guide antiviral defense in prokaryotes. (2013) (0)
- Non-specific degradation of transcripts promotes plasmid clearance during type III-A CRISPR–Cas immunity (2019) (0)
- Faculty Opinions recommendation of Inter- and intraspecies metabolite exchange promotes virulence of antibiotic-resistant Staphylococcus aureus. (2014) (0)
- Molecular mechanisms of CRISPR–Cas spacer acquisition (2018) (0)
- crystal structure of cA4-activated Card1 (2020) (0)
- Faculty Opinions recommendation of A chemical defence against phage infection. (2019) (0)
- Incomplete prophage tolerance by type III-A CRISPR-Cas systems reduces the fitness of lysogenic hosts (2018) (0)
- Editorial overview: Novel technologies in microbiology: Recent advances in techniques in microbiology. (2014) (0)
- Systems, methods and compositions of the CRISPR-cas components for sequence manipulation. (2013) (0)
- Faculty Opinions recommendation of Intervening sequences of regularly spaced prokaryotic repeats derive from foreign genetic elements. (2013) (0)
- Sortases, transpeptidases that anchor proteins to the envelope of gram -positive bacteria (2007) (0)
- Faculty Opinions recommendation of Optimization of lag time underlies antibiotic tolerance in evolved bacterial populations. (2014) (0)
- crystal structure of cA4-activated Card1(D294N) (2020) (0)
- Faculty Opinions recommendation of Cas4-Dependent Prespacer Processing Ensures High-Fidelity Programming of CRISPR Arrays. (2018) (0)
- CRISPR/Cas, the RNA‐based adaptive immune system of prokaryotes (2013) (0)
- Recombination between phages and CRISPR−cas loci facilitates horizontal gene transfer in staphylococci (2019) (0)
- crystal structure of cA6-bound Card1 (2020) (0)
- crystal structure of apo Card1 (2020) (0)
- Faculty Opinions recommendation of The type VI secretion system of Vibrio cholerae fosters horizontal gene transfer. (2016) (0)
- Faculty Opinions recommendation of Bacterial cGAS-like enzymes synthesize diverse nucleotide signals. (2019) (0)
- Faculty Opinions recommendation of Engineering orthogonal signalling pathways reveals the sparse occupancy of sequence space. (2019) (0)
- Activation and self-inactivation mechanisms of the cyclic oligoadenylate-dependent CRISPR ribonuclease Csm6 (2020) (0)
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What Schools Are Affiliated With Luciano Marraffini?
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