Lucio Guido Costa
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Biology
Lucio Guido Costa's Degrees
- PhD Molecular Biology Stanford University
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(Suggest an Edit or Addition)Lucio Guido Costa's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Mice lacking serum paraoxonase are susceptible to organophosphate toxicity and atherosclerosis (1998) (1098)
- Current issues in organophosphate toxicology. (2006) (653)
- Xestospongins: Potent Membrane Permeable Blockers of the Inositol 1,4,5-Trisphosphate Receptor (1997) (578)
- Developmental neurotoxicity of polybrominated diphenyl ether (PBDE) flame retardants. (2007) (546)
- Modulation of paraoxonase (PON1) activity. (2005) (476)
- Review of the Toxicology of Chlorpyrifos With an Emphasis on Human Exposure and Neurodevelopment (2008) (408)
- Polyphenols and health: what compounds are involved? (2010) (346)
- Mechanisms of Neuroprotection by Quercetin: Counteracting Oxidative Stress and More (2016) (333)
- Neurotoxicity of pesticides: a brief review. (2008) (320)
- Developmental neuropathology of environmental agents. (2004) (310)
- Polybrominated diphenyl ether (PBDE) flame retardants: environmental contamination, human body burden and potential adverse health effects. (2008) (305)
- Polybrominated diphenyl ethers: neurobehavioral effects following developmental exposure. (2003) (304)
- Catalytic efficiency determines the in-vivo efficacy of PON1 for detoxifying organophosphorus compounds. (2000) (271)
- Neurotoxicity of traffic‐related air pollution (2017) (245)
- Spectrophotometric assays for the enzymatic hydrolysis of the active metabolites of chlorpyrifos and parathion by plasma paraoxonase/arylesterase. (1989) (229)
- Effects of perinatal exposure to a polybrominated diphenyl ether (PBDE 99) on mouse neurobehavioural development. (2002) (220)
- Measurement of paraoxonase (PON1) status as a potential biomarker of susceptibility to organophosphate toxicity. (2005) (220)
- Review of the toxicology of chlorpyrifos with an emphasis on human exposure and neurodevelopment. (2008) (218)
- Functional genomic of the paraoxonase (PON1) polymorphisms: effects on pesticide sensitivity, cardiovascular disease, and drug metabolism. (2003) (216)
- Formation of N-7-(2-carbamoyl-2-hydroxyethyl)guanine in DNA of the mouse and the rat following intraperitoneal administration of [14C]acrylamide. (1995) (216)
- Organophosphorus insecticides chlorpyrifos and diazinon and oxidative stress in neuronal cells in a genetic model of glutathione deficiency. (2007) (206)
- Determination of hemoglobin adducts in humans occupationally exposed to acrylamide. (1993) (204)
- A mechanistic view of polybrominated diphenyl ether (PBDE) developmental neurotoxicity. (2014) (195)
- The role of paraoxonase (PON1) in the detoxication of organophosphates and its human polymorphism. (1999) (187)
- Acetylcholine as a mitogen: muscarinic receptor-mediated proliferation of rat astrocytes and human astrocytoma cells. (1996) (181)
- Paraoxonase protects against chlorpyrifos toxicity in mice. (1995) (179)
- Serum paraoxonase and its influence on paraoxon and chlorpyrifos-oxon toxicity in rats. (1990) (177)
- Serum paraoxonase status: a major factor in determining resistance to organophosphates. (1993) (172)
- Antiglycative and neuroprotective activity of colon-derived polyphenol catabolites. (2011) (169)
- Pharmacological and dietary modulators of paraoxonase 1 (PON1) activity and expression: the hunt goes on. (2011) (168)
- Neurotoxicants Are in the Air: Convergence of Human, Animal, and In Vitro Studies on the Effects of Air Pollution on the Brain (2014) (167)
- Acrylamide is metabolized to glycidamide in the rat: evidence from hemoglobin adduct formation. (1990) (159)
- Formation of hemoglobin adducts of acrylamide and its epoxide metabolite glycidamide in the rat. (1991) (154)
- A comparison of the antinociceptive responses to the GABA-receptor agonists THIP and baclofen (1985) (153)
- Paraoxonases-1, -2 and -3: What are their functions? (2016) (143)
- Tolerance to anticholinesterase compounds in mammals. (1982) (143)
- Paraoxonase 1 (PON1) as a genetic determinant of susceptibility to organophosphate toxicity. (2013) (142)
- Paraoxonase (PON 1) as a biomarker of susceptibility for organophosphate toxicity (2003) (139)
- The Role of Glia in Neurotoxicity (1996) (132)
- Maturation-dependent effects of chlorpyrifos and parathion and their oxygen analogs on acetylcholinesterase and neuronal and glial markers in aggregating brain cell cultures. (2000) (130)
- Effects of air pollution on the nervous system and its possible role in neurodevelopmental and neurodegenerative disorders. (2020) (129)
- Differential in vitro neurotoxicity of the flame retardant PBDE-99 and of the PCB Aroclor 1254 in human astrocytoma cells. (2004) (128)
- Organophosphorus Compounds at 80: Some Old and New Issues. (2018) (127)
- [3H]Nicotine binding in rat brain: alteration after chronic acetylcholinesterase inhibition. (1983) (127)
- Expression of human paraoxonase (PON1) during development. (2003) (119)
- Human and rabbit paraoxonases: purification, cloning, sequencing, mapping and role of polymorphism in organophosphate detoxification. (1993) (116)
- Low concentrations of the brominated flame retardants BDE-47 and BDE-99 induce synergistic oxidative stress-mediated neurotoxicity in human neuroblastoma cells. (2010) (110)
- Polymorphisms of Paraoxonase (PON1) and Their Significance in Clinical Toxicology of Organophosphates (2003) (107)
- Advancing the science of developmental neurotoxicity (DNT): testing for better safety evaluation. (2012) (107)
- Human PON1, a biomarker of risk of disease and exposure. (2010) (107)
- Inhibition of Muscarinic Receptor‐Stimulated Glial Cell Proliferation by Ethanol (1996) (106)
- Domoic acid as a developmental neurotoxin. (2010) (105)
- Is decabromodiphenyl ether (BDE-209) a developmental neurotoxicant? (2011) (105)
- Differential alterations of cholinergic muscarinic receptors during chronic and acute tolerance to organophosphorus insecticides. (1982) (104)
- Neurotoxicity of a polybrominated diphenyl ether mixture (DE-71) in mouse neurons and astrocytes is modulated by intracellular glutathione levels. (2008) (103)
- Early developmental exposure to BDE 99 or Aroclor 1254 affects neurobehavioural profile: interference from the administration route. (2005) (99)
- Neurotoxicity of Domoic Acid in Cerebellar Granule Neurons in a Genetic Model of Glutathione Deficiency (2006) (98)
- Toxicity of chlorpyrifos and chlorpyrifos oxon in a transgenic mouse model of the human paraoxonase (PON1) Q192R polymorphism (2005) (94)
- Cholesterol efflux is differentially regulated in neurons and astrocytes: implications for brain cholesterol homeostasis. (2013) (94)
- Gender differences in brain susceptibility to oxidative stress are mediated by levels of paraoxonase-2 expression. (2013) (92)
- Genetic and temporal determinants of pesticide sensitivity: role of paraoxonase (PON1). (2000) (91)
- Developmental changes in muscarinic receptor-stimulated phosphoinositide metabolism in rat brain. (1987) (90)
- A genetic polymorphism of MAO-B modifies the association of cigarette smoking and Parkinson's disease (1998) (89)
- Developmental Neurotoxicity: Some Old and New Issues (2012) (88)
- Sex and genetic differences in the effects of acute diesel exhaust exposure on inflammation and oxidative stress in mouse brain. (2016) (87)
- The neurotoxicity of organochlorine and pyrethroid pesticides. (2015) (86)
- A pilot study of occupational and environmental risk factors for Parkinson's disease. (1991) (83)
- Modulation of Neuritogenesis by Astrocyte Muscarinic Receptors* (2008) (83)
- Involvement of glial cells in the neurotoxicity of parathion and chlorpyrifos. (2004) (82)
- Role of paraoxonase (PON1) status in pesticide sensitivity: genetic and temporal determinants. (2005) (80)
- Biomarker research in neurotoxicology: the role of mechanistic studies to bridge the gap between the laboratory and epidemiological investigations. (1996) (80)
- Association of a polymorphism in intron 13 of the monoamine oxidase B gene with Parkinson disease. (1998) (80)
- Biochemical markers of neurotoxicity. A review of mechanistic studies and applications. (1996) (79)
- Comparative cytotoxicity and intracellular accumulation of five polybrominated diphenyl ether congeners in mouse cerebellar granule neurons. (2010) (77)
- Spatial memory impairment and central muscarinic receptor loss following prolonged treatment with organophosphates. (1988) (76)
- Paraoxonase 2 (PON2) in the mouse central nervous system: a neuroprotective role? (2011) (75)
- Comparative studies on the neuro- and reproductive toxicity of acrylamide and its epoxide metabolite glycidamide in the rat. (1992) (75)
- Mouse cerebellar astrocytes protect cerebellar granule neurons against toxicity of the polybrominated diphenyl ether (PBDE) mixture DE-71. (2009) (75)
- Effect of diethylmaleate and other glutathione depletors on protein synthesis. (1986) (74)
- Reduced [3H]quinuclidinyl benzilate binding to muscarinic receptors in disulfoton-tolerant mice. (1981) (74)
- Neuropsychological performance among agricultural pesticide applicators. (1992) (74)
- Glutathione levels modulate domoic acid induced apoptosis in mouse cerebellar granule cells. (2007) (73)
- Effect of organophosphorus insecticides and their metabolites on astroglial cell proliferation. (2005) (73)
- Biochemical markers of neurotoxicity: research strategies and epidemiological applications. (1995) (69)
- Structural Effects and Neurofunctional Sequelae of Developmental Exposure to Psychotherapeutic Drugs: Experimental and Clinical Aspects (2004) (68)
- Activation of NMDA receptors induces protein kinase A‐mediated phosphorylation and degradation of matrin 3. Blocking these effects prevents NMDA‐induced neuronal death (2005) (68)
- Interaction of blood lead and delta-aminolevulinic acid dehydratase genotype on markers of heme synthesis and sperm production in lead smelter workers. (1998) (68)
- Effects of inorganic and organic mercury on intracellular calcium levels in rat T lymphocytes. (1993) (66)
- Modulation of muscarinic receptors and acetylcholinesterase activity in lymphocytes and in brain areas following repeated organophosphate exposure in rats. (1993) (66)
- Neurotoxicity testing: a discussion of in vitro alternatives. (1998) (66)
- Microglia mediate diesel exhaust particle-induced cerebellar neuronal toxicity through neuroinflammatory mechanisms. (2016) (65)
- Effects of ethanol on muscarinic receptor-stimulated phosphoinositide metabolism during brain development. (1989) (65)
- Interaction of mercury compounds with muscarinic receptor subtypes in the rat brain. (1996) (64)
- Application of in vitro neurotoxicity testing for regulatory purposes: Symposium III summary and research needs. (2008) (64)
- Basic toxicology of pesticides. (1997) (62)
- 5' and 3' region variability in the dopamine transporter gene (SLC6A3), pesticide exposure and Parkinson's disease risk: a hypothesis-generating study. (2006) (62)
- Alpha 2-adrenoceptors as a target for formamidine pesticides: in vitro and in vivo studies in mice. (1988) (62)
- Paraoxonase (PON1) gene in mice: sequencing, chromosomal localization and developmental expression. (1997) (62)
- Interactions of neurotoxicants with neurotransmitter systems. (1988) (61)
- Extracts of various species of Epilobium inhibit proliferation of human prostate cells (2003) (60)
- Developmental Neurotoxicity of Traffic-Related Air Pollution: Focus on Autism (2017) (60)
- Paraoxonase-2 (PON2) in brain and its potential role in neuroprotection. (2014) (60)
- Muscarinic cholinergic receptor signal transduction as a potential target for the developmental neurotoxicity of ethanol. (1999) (60)
- The brominated flame retardant BDE-47 causes oxidative stress and apoptotic cell death in vitro and in vivo in mice. (2015) (59)
- Characterization of the Effect of Epilobium Extracts on Human Cell Proliferation (2003) (59)
- Signal transduction in environmental neurotoxicity. (1998) (59)
- Activation of mitogen‐activated protein kinase by muscarinic receptors in astroglial cells: Role in DNA synthesis and effect of ethanol (2001) (58)
- Contaminants in Fish: Risk-Benefit Considerations (2007) (57)
- An in vitro approach to assess the toxicity of certain food contaminants: methylmercury and polychlorinated biphenyls. (2007) (57)
- Dopamine transporter (SLC6A3) 5′ region haplotypes significantly affect transcriptional activity in vitro but are not associated with Parkinson's disease (2005) (57)
- Exposure to 60-Hz magnetic fields and proliferation of human astrocytoma cells in vitro. (2000) (57)
- Evaluation of DNA Damage Induced by 2 Polybrominated Diphenyl Ether Flame Retardants (BDE-47 and BDE-209) in SK-N-MC Cells (2012) (53)
- Developmental impact of air pollution on brain function (2019) (53)
- A selective decrease of cholinergic muscarinic receptors in the visual cortex of adult rats following developmental lead exposure (1983) (52)
- Carbachol- and norepinephrine-stimulated phosphoinositide metabolism in rat brain: effect of chronic cholinesterase inhibition. (1986) (52)
- Protein adducts as biomarkers of exposure to organophosphorus compounds. (2013) (51)
- Developmental neurotoxicity: do similar phenotypes indicate a common mode of action? A comparison of fetal alcohol syndrome, toluene embryopathy and maternal phenylketonuria. (2002) (51)
- Pharmacogenomic considerations of the paraoxonase polymorphisms. (2002) (51)
- Scientific information on mycotoxins and natural plant toxicants (2009) (51)
- The PON1 gene and detoxication. (2000) (50)
- NTP-CERHR Expert Panel Report on the reproductive and developmental toxicity of amphetamine and methamphetamine. (2005) (50)
- Paraoxonase (PON1): from toxicology to cardiovascular medicine. (2005) (49)
- Regional development of carbachol-, glutamate-, norepinephrine-, and serotonin-stimulated phosphoinositide metabolism in rat brain. (1991) (48)
- Effect of styrene oxide on rat brain glutathione. (1991) (48)
- Modulation of Paraoxonase 2 (PON2) in Mouse Brain by the Polyphenol Quercetin: A Mechanism of Neuroprotection? (2013) (48)
- Trimethyltin inhibits uptake of neurotransmitters into mouse forebrain synaptosomes. (1982) (47)
- Polybrominated Diphenyl Ethers (PBDEs) (2014) (46)
- Factors involved in the differential acute toxicity of the insecticides chlorpyrifos and methyl chlorpyrifos in mice. (1982) (46)
- Nutrition and alcohol neurotoxicity. (1994) (46)
- Cyclic GMP formation induced by muscarinic receptors is mediated by nitric oxide synthesis in rat cortical primary cultures (1993) (45)
- Manganese inhibits the ability of astrocytes to promote neuronal differentiation. (2009) (45)
- Paraoxonase 1 (PON1) modulates the toxicity of mixed organophosphorus compounds. (2009) (44)
- Bridging the gap between in vitro and in vivo models for neurotoxicology. (1999) (44)
- Ethanol inhibits neuritogenesis induced by astrocyte muscarinic receptors (2010) (44)
- Apoptosis induced by domoic acid in mouse cerebellar granule neurons involves activation of p38 and JNK MAP kinases (2008) (43)
- Primary neurons in culture and neuronal cell lines for in vitro neurotoxicological studies. (2011) (43)
- Prenatal and early-life diesel exhaust exposure causes autism-like behavioral changes in mice (2018) (43)
- Identification of m3, m4 and m5 subtypes of muscarinic receptor mRNA in human blood mononuclear cells (1995) (43)
- Effect of ethanol on protein kinase Cζ and p70S6 kinase activation by carbachol: a possible mechanism for ethanol‐induced inhibition of glial cell proliferation (2002) (41)
- Use of aggregating brain cell cultures to study developmental effects of organophosphorus insecticides. (2000) (41)
- Genetically determined susceptibility to organophosphorus insecticides and nerve agents: developing a mouse model for the human PON1 polymorphism. (1998) (41)
- Muscarinic cholinergic binding sites on rat lymphocytes. (1988) (41)
- Species Differences in Serum Paraoxonase Correlate with Sensitivity to Paraoxon Toxicity (1987) (41)
- The effects of ethanol on glial cell proliferation: relevance to the fetal alcohol syndrome. (1997) (41)
- Ethanol selectively interferes with the trophic action of NMDA and carbachol on cultured cerebellar granule neurons undergoing apoptosis. (1998) (40)
- Determination of Paraoxonase 1 Status and Genotypes at Specific Polymorphic Sites (2004) (40)
- Genetic polymorphisms in Parkinson's disease. (1998) (40)
- Gender difference in the interaction of smoking and monoamine oxidase B intron 13 genotype in Parkinson's disease. (2002) (39)
- Astrocytes protect against diazinon- and diazoxon-induced inhibition of neurite outgrowth by regulating neuronal glutathione. (2014) (39)
- Possible role of protein kinase C zeta in muscarinic receptor-induced proliferation of astrocytoma cells. (2000) (39)
- Inorganic lead activates the mitogen-activated protein kinase kinase-mitogen-activated protein kinase-p90(RSK) signaling pathway in human astrocytoma cells via a protein kinase C-dependent mechanism. (2002) (38)
- Nuclear factor κb activation by muscarinic receptors in astroglial cells: effect of ethanol (2003) (38)
- Reduced muscarinic receptor binding in tissues of rats tolerant to the insecticide disulfoton. (1981) (37)
- Acute exposure to diesel exhaust impairs adult neurogenesis in mice: prominence in males and protective effect of pioglitazone (2018) (37)
- The role of protein kinase C α and ε isozymes in DNA synthesis induced by muscarinic receptors in a glial cell line (1998) (37)
- Behavioral and biochemical effects of postnatal parathion exposure in the rat. (1988) (36)
- Activation of phosphatidylinositol 3 kinase by muscarinic receptors in astrocytoma cells (2001) (36)
- Inorganic lead stimulates DNA synthesis in human astrocytoma cells: role of protein kinase Cα (2001) (36)
- Developmental neurotoxicity of ethanol: in vitro inhibition of muscarinic receptor-stimulated phosphoinositide metabolism in brain from neonatal but not adult rats (1990) (35)
- Polybrominated diphenyl ether (PBDE) flame retardants (2008) (35)
- Role of autophagy in environmental neurotoxicity. (2018) (35)
- Synergistic interactions between PBDEs and PCBs in human neuroblastoma cells (2014) (35)
- Genetic polymorphism of dopamine D2 receptors in Parkinson's disease and interactions with cigarette smoking and MAO-B intron 13 polymorphism (2000) (34)
- Role of phospholipase D signaling in ethanol‐induced inhibition of carbachol‐stimulated DNA synthesis of 1321N1 astrocytoma cells (2004) (34)
- Inhibition of γ-[3H]aminobutyric acid uptake by organotin compounds in vitro (1985) (34)
- Diazinon and diazoxon impair the ability of astrocytes to foster neurite outgrowth in primary hippocampal neurons. (2014) (34)
- Evaluation of the neurotoxicity of glycidamide, an epoxide metabolite of acrylamide: behavioral, neurochemical and morphological studies. (1995) (33)
- Linear versus nonlinear models for hemoglobin adduct formation by acrylamide and its metabolite glycidamide: implications for risk estimation. (1992) (33)
- Na+/K(+)-ATPase in rat brain and erythrocytes as a possible target and marker, respectively, for neurotoxicity: studies with chlordecone, organotins and mercury compounds. (1990) (33)
- The Activation of M1 Muscarinic Receptor Signaling Induces Neuronal Differentiation in Pyramidal Hippocampal Neurons (2009) (32)
- Characterization of the in vitro transcriptional activity of polymorphic alleles of the human monoamine oxidase-B gene (2005) (32)
- Biochemical and molecular neurotoxicology: relevance to biomarker development, neurotoxicity testing and risk assessment. (1998) (32)
- Ethanol Induces Cholesterol Efflux and Up-regulates ATP-binding Cassette Cholesterol Transporters in Fetal Astrocytes* (2007) (32)
- Genotype combinations for monoamine oxidase-B intron 13 polymorphism and dopamine D2 receptor TaqIB polymorphism are associated with ever-smoking status among men (2005) (32)
- In vivo ethanol decreases phosphorylated MAPK and p70S6 kinase in the developing rat brain. (2003) (32)
- Determination of organophosphorus insecticides, their oxygen analogs and metabolites by high pressure liquid chromatography (1982) (32)
- Peripheral markers of neurochemical function among workers exposed to styrene. (1992) (32)
- Measurements of cell death in neuronal and glial cells. (2011) (31)
- Organophosphate pesticide exposure in a group of Washington State orchard applicators. (1992) (31)
- Toxicology of Pesticides: Experimental, Clinical and Regulatory Perspectives (1987) (31)
- Signal transduction mechanisms involved in the antiproliferative effects of ethanol in glial cells. (2003) (31)
- Paraoxonase-1 and Early-Life Environmental Exposures. (2016) (31)
- Passive avoidance retention in mice tolerant to the organophosphorus insecticide disulfoton. (1982) (30)
- Retinoic Acid Isomers Up-Regulate ATP Binding Cassette A1 and G1 and Cholesterol Efflux in Rat Astrocytes: Implications for Their Therapeutic and Teratogenic Effects (2011) (30)
- Effect of phenylalanine and its metabolites on the proliferation and viability of neuronal and astroglial cells: possible relevance in maternal phenylketonuria. (2000) (30)
- Mechanisms of neurotoxicity: applications to human biomonitoring. (1995) (29)
- A nonlinear dosimetric model for hemoglobin adduct formation by the neurotoxic agent acrylamide and its genotoxic metabolite glycidamide. (1993) (29)
- Genetic Factors in Susceptibility: Serum PON1 Variation Between Individuals and Species (2002) (29)
- Intracellular signal transduction pathways as targets for neurotoxicants. (2001) (29)
- Expression of cholinergic muscarinic receptor subtypes mRNA in rat blood mononuclear cells. (1994) (29)
- Cytotoxic and genotoxic effects of styrene-7,8-oxide in neuroadrenergic Pc 12 cells. (1992) (29)
- Developmental neurotoxicity of ethanol: further evidence for an involvement of muscarinic receptor-stimulated phosphoinositide hydrolysis. (1994) (28)
- Ethanol inhibits muscarinic receptor-induced axonal growth in rat hippocampal neurons. (2009) (27)
- Repeated developmental exposure of mice to chlorpyrifos oxon is associated with paraoxonase 1 (PON1)-modulated effects on cerebellar gene expression. (2011) (27)
- Paraoxonase (PON1) in Health and Disease (2002) (27)
- Interaction of organophosphorus compounds with muscarinic receptors in SH-SY5Y human neuroblastoma cells. (1994) (27)
- Interaction of σ‐Compounds with Receptor‐Stimulated Phosphoinositide Metabolism in the Rat Brain (1990) (26)
- Modulation of DNA Synthesis by Muscarinic Cholinergic Receptors (2001) (26)
- Muscarinic receptors prevent oxidative stress‐mediated apoptosis induced by domoic acid in mouse cerebellar granule cells (2009) (26)
- Long-term effects of developmental exposure to low doses of PCB 126 and methylmercury. (2010) (26)
- NTP-CERHR Expert Panel Report on the reproductive and developmental toxicity of methylphenidate. (2005) (26)
- Characterization of cholinergic muscarinic receptor-stimulated phosphoinositide metabolism in brain from immature rats. (1990) (26)
- The Functional Consequences of Polymorphisms in the Human PON1 Gene (2008) (26)
- Paraoxonase 1 promoter and coding region polymorphisms in Parkinson’s disease (2003) (26)
- Neurobehavioral assessment of mice following repeated postnatal exposure to chlorpyrifos-oxon. (2012) (26)
- Muscarinic Receptors and the Developing Nervous System (1993) (25)
- Ethanol impairs muscarinic receptor-induced neuritogenesis in rat hippocampal slices: Role of astrocytes and extracellular matrix proteins. (2011) (25)
- Developmental Neurotoxicity of Toluene: in vivo and in vitro Effects on Astroglial Cells (2003) (25)
- Phomopsins: an overview of phytopathological and chemical aspects, toxicity, analysis and occurrence (2011) (25)
- The emerging field of ecogenetics. (2000) (25)
- Effects of postnatal ethanol exposure at different developmental phases on neurotrophic factors and phosphorylated proteins on signal transductions in rat brain. (2008) (24)
- Chronic exposure to ammonia induces isoform‐selective alterations in the intracellular distribution and NMDA receptor‐mediated translocation of protein kinase C in cerebellar neurons in culture (2005) (24)
- Prenatal and early life diesel exhaust exposure disrupts cortical lamina organization: Evidence for a reelin-related pathogenic pathway induced by interleukin-6 (2019) (24)
- In vitro and in vivo modulation of cholinergic muscarinic receptors in rat lymphocytes and brain by cholinergic agents. (1990) (23)
- Platelet monoamine oxidase B activity in workers exposed to styrene (1994) (23)
- Neurobehavioral assessment of rats exposed to low doses of PCB126 and methyl mercury during development. (2008) (23)
- 3H-spiperone labels sigma receptors, not dopamine D2 receptors, in rat and human lymphocytes. (1991) (22)
- Toxicology of Pesticides: A Brief History (1987) (22)
- Paraoxonase-1 and clopidogrel efficacy (2011) (22)
- Behavioral Characterization of GCLM-Knockout Mice, a Model for Enhanced Susceptibility to Oxidative Stress (2011) (22)
- Visual acuity deficits following neonatal lead exposure: cholinergic interactions. (1982) (22)
- INTERACTION OF CHOLINE WITH NICOTINIC AND MUSCARINIC CHOLINERGIC RECEPTORS IN THE RAT BRAIN IN VITRO (1984) (22)
- Effect of ethanol on muscarinic receptor‐induced calcium responses in astroglia (2000) (22)
- Muscarinic receptor alterations as a mechanism of anticholinesterase tolerance. (1983) (21)
- Evaluation of brominated diphenyl ether‐99 toxicity with Raphidocelis subcapitata and Daphnia magna (2003) (21)
- The phosphoinositide/protein kinase C system as a potential target for neurotoxicity. (1990) (21)
- Acute and chronic effects of the pesticide amitraz on α2-adrenoceptors in the mouse brain (1989) (20)
- Antinociceptive and hypothermic effects of trimethyltin. (1982) (20)
- Effects of ethanol on calcium homeostasis in the nervous system (1999) (20)
- PON1 and Organophosphate Toxicity (2002) (20)
- Inhibition of muscarinic receptor-induced proliferation of astroglial cells by ethanol: mechanisms and implications for the fetal alcohol syndrome. (2002) (20)
- Decreased muscarinic binding sites in small intestine from mice treated with neostigmine. (1981) (19)
- Aggregating Brain Cell Cultures for Neurotoxicological Studies (2004) (19)
- Two subtypes of enteric non-opioid σ receptors in guinea-pig cholinergic motor neurons (1991) (19)
- Neurobehavioral assessment of mice following repeated oral exposures to domoic acid during prenatal development. (2017) (19)
- Muscarinic receptors, protein kinase C isozymes and proliferation of astroglial cells: effects of ethanol. (2000) (19)
- Tolerance to the carbamate insecticide propoxur. (1981) (18)
- Paraoxonase polymorphisms and toxicity of organophosphates (2006) (18)
- Modulation of M1 and M2 muscarinic receptor subtypes following repeated organophosphate exposure in rats. (1992) (18)
- Effects of organophosphate exposure on muscarinic acetylcholine receptor subtype mRNA levels in the adult rat. (1996) (18)
- Inhibition of protein synthesis by trimethyltin. (1986) (18)
- Gene-environment interactions fundamentals of ecogenetics (2006) (18)
- Characterization of muscarinic cholinergic receptors in the submandibular gland of the rat. (1985) (17)
- Effects of thallium on primary cultures of testicular cells. (1992) (17)
- Biomarkers in environmental medicine: alterations of cell signalling as early indicators of neurotoxicity. (1994) (17)
- The toxicity of mixtures of specific organophosphate compounds is modulated by paraoxonase 1 status. (2010) (17)
- Effect of trimethyltin on chemically-induced seizures. (1982) (16)
- Conditioned taste aversion induced by organophosphate compounds in rats (1986) (16)
- Peripheral blood cell activities of monoamine oxidase B and superoxide dismutase in Parkinson's disease (1992) (16)
- Unidirectional cross-tolerance between the carbamate insecticide propoxur and the organophosphate disulfoton in mice. (1983) (16)
- Developmental expression of paraoxonase 2. (2016) (16)
- Muscarinic receptor stimulation of phospholipase D activity in the developing rat brain (1995) (16)
- Muscarinic receptor-induced calcium responses in astroglia. (2000) (16)
- Paraoxonase (PON1) and Organophosphate Toxicity (2008) (16)
- Measurements of astrocyte proliferation. (2011) (15)
- The formamidine pesticides chlordimeform and amitraz decrease hepatic glutathione in mice through an interaction with alpha 2-adrenoceptors. (1991) (15)
- Muscarinic receptor-activated signal transduction pathways involved in the neuritogenic effect of astrocytes in hippocampal neurons. (2011) (15)
- Ethanol inhibits muscarinic receptor-mediated DNA synthesis and signal transduction in human fetal astrocytes (2003) (15)
- Exposure to low levels of hexavalent chromium: target doses and comparative effects on two human pulmonary cell lines. (2008) (15)
- Effects of alcohol on immediate-early gene expression in primary cultures of rat cortical astrocytes. (1999) (14)
- In vitro assessment of mutagenicity and clastogenicity of BDE‐99, a pentabrominated diphenyl ether flame retardant (2003) (14)
- Fibroblast heterogeneity of signal transduction mechanisms to complement-C1q. Analyses of calcium mobilization, inositol phosphate accumulation, and protein kinases-C redistribution. (1998) (14)
- Interaction of aluminum ions with phosphoinositide metabolism in rat cerebral cortical membranes. (1991) (14)
- Postnatal development of muscarinic receptor-stimulated phosphoinositide metabolism in mouse cerebral cortex: sensitivity to ethanol. (1995) (13)
- Inhibition of muscarinic receptor- and G-protein-dependent phosphoinositide metabolism in cerebrocortical membranes from neonatal rats by ethanol. (1992) (13)
- Signal transduction mechanisms in developmental neurotoxicity: the phosphoinositide pathway. (1994) (13)
- Disruption of cholesterol homeostasis in the developing brain as a potential mechanism contributing to the developmental neurotoxicity of ethanol: an hypothesis. (2005) (13)
- Formamidine pesticides and alpha 2-adrenoceptors: studies with amitraz and chlordimeform in rats and development of a radioreceptor binding assay. (1989) (13)
- Interaction of the neurotoxic pesticides ivermectin and lindane with the enteric GABAA receptor-ionophore complex in the guinea-pig. (1993) (13)
- The EcoRV genetic polymorphism of human monoamine oxidase type A is not associated with Parkinson's disease and does not modify the effect of smoking on Parkinson's disease (2000) (13)
- Characterization of ouabain-induced phosphoinositide hydrolysis in brain slices of the neonatal rat (1990) (12)
- Muscarinic M2 receptors in rat brain labeled with [3H] AF-DX 384. (1991) (12)
- Administration of ethanol during brain growth spurt causes dose-dependent microencephaly and inhibition of muscarinic receptor-stimulated phosphoinositide metabolism in the rat (1994) (12)
- Muscarinic receptor alterations following neostigmine treatment. (1982) (12)
- Predictive models for neurotoxicity assessment (2010) (12)
- Metals and Paraoxonases. (2017) (12)
- Biometals in neurodegenerative diseases: mechanisms and therapeutics (2017) (11)
- Assessment of cholesterol homeostasis in astrocytes and neurons. (2011) (11)
- Assessment of glutathione homeostasis. (2011) (11)
- Effects of ethanol administration on cerebral non-protein sulfhydryl content in rats exposed to styrene vapour. (1996) (11)
- Quantification of synaptic structure formation in cocultures of astrocytes and hippocampal neurons. (2011) (11)
- Commentary Modulation of paraoxonase (PON1) activity (2005) (10)
- Inhibition of muscarinic receptor-stimulated phosphoinositide metabolism by cocaine, norcocaine and cocaethylene in rat brain. (1994) (10)
- Prenatal Ethanol Exposure Up-Regulates the Cholesterol Transporters ATP-Binding Cassette A1 and G1 and Reduces Cholesterol Levels in the Developing Rat Brain. (2014) (9)
- Absorption, distribution and excretion of [14C]carmoisine in mice after oral and intravenous administration. (1981) (9)
- Oxidative stress as a potential mechanism for developmental neurotoxicity of polybrominated diphenylether (PBDE) flame retardants (2010) (9)
- Interaction of the pyrethroid insecticides tetramethrin and cypermethrin with enteric cholinergic transmission in the guinea-pig. (1989) (9)
- Gene-Environment Interactions: Paraoxonase (PON1) and Sensitivity to Organophosphate Toxicity (2006) (9)
- Antinociceptive effect of the GABAmimetic 4,5,6,7-tetrahydroisoxazolo [5, 4-c]pyridin-3-ol (THIP): chronic treatment increases alpha-2 adrenoceptors in the mouse brain. (1984) (9)
- Metabolic studies as a basis for the interpretation of metal toxicity. (1992) (9)
- Effects of trimethyltin on granule cells excitability in the in vitro rat dentate gyrus. (1987) (9)
- Ethanol inhibits muscarinic receptor-stimulated phosphoinositide metabolism and calcium mobilization in rat primary cortical cultures (1995) (9)
- Potassium ions potentiate the muscarinic receptor-stimulated phosphoinositide metabolism in cerebral cortex slices: A comparison of neonatal and adult rats (2004) (9)
- Interaction of short chain aliphatic alcohols with muscarinic receptor-stimulated phosphoinositide metabolism in cerebral cortex from neonatal and adult rats. (1991) (9)
- Interaction of the pesticide chlordimeform with adrenergic receptors in mouse brain: an in vitro study (1987) (9)
- Chronic administration of an organophosphorus insecticide to rats alters cholinergic muscarinic receptors in the pancreas. (1984) (9)
- Interaction between acetaminophen and organophosphates in mice. (1984) (8)
- In vitro neurotoxicology: an introduction. (2011) (8)
- In Vitro and Alternative Approaches to Developmental Neurotoxicity (2017) (8)
- Environmental Factors in Neurodevelopmental and Neurodegenerative Disorders (2015) (8)
- Effect of styrene on monoamine oxidase B activity in rat brain. (1999) (8)
- Effects of styrene oxide on differentiation and viability of rodent embryo cultures. (1994) (8)
- Time-, concentration-, and age-dependent inhibition of muscarinic receptor-stimulated phosphoinositide metabolism by ethanol in the developing rat brain (1991) (8)
- The metabolic disposition of 14C-labelled carmoisine in the rat after oral and intravenous administration. (1982) (8)
- Interaction of ethanol with muscarinic receptor-stimulated phosphoinositide metabolism during the brain growth spurt in the rat: role of acetaldehyde (1993) (7)
- Traffic-Related Air Pollution and Neurodegenerative Diseases: Epidemiological and Experimental Evidence, and Potential Underlying Mechanisms (2017) (7)
- Low-level domoic acid protects mouse cerebellar granule neurons from acute neurotoxicity: role of glutathione. (2013) (7)
- 14 – Role of Second-Messenger Systems In Response to Organophosphorus Compounds (1992) (7)
- Interaction of Insecticides with the Nervous System (1987) (7)
- Effect of subchronic ethanol ingestion on styrene‐induced damage to the tracheal and pulmonary epithelium of the rat (1998) (7)
- Lack of m2 muscarinic acetylcholine receptor mRNA in rat lymphocytes (1994) (7)
- Disruption of cholesterol homeostasis in developmental neurotoxicity (2011) (7)
- Toxicology of the Nervous System (2014) (7)
- Overview of Neurotoxicology (2017) (7)
- Urinary mercapturic acid diastereoisomers in rats subchronically exposed to styrene and ethanol (1996) (6)
- Cholinergic and opiate involvement in the antinociceptive effect of diisopropylfluorophosphate (1986) (6)
- Alcohol and Glia in the Developing Brain (2004) (6)
- Placental transfer and tissue localization of [14C]carmoisine in the pregnant rat. (1982) (6)
- Diet-brain connections: role of neurotoxicants. (2005) (6)
- Effects of the muscarinic agonist oxotremorine on membrane fluidity in rat lymphocytes. (1993) (5)
- Gastrointestinal Toxicology (2011) (5)
- Heterogeneity of cholinergic muscarinic receptors coupled to phosphoinositide metabolism in immature rat brain. (1995) (5)
- Sonic hedgehog in Smith-Lemli-Opitz syndrome and tumor development. (2008) (5)
- Paraoxonase 1: Structure, Function, and Polymorphisms (2011) (5)
- Polybrominated Diphenyl Ethers (2014) (5)
- Specific binding of [3H]methylscopolamine to glass fibre filters (1987) (5)
- Ontogeny of Second Messenger Systems (1998) (5)
- Acute and chronic effects of the pesticide amitraz on alpha 2-adrenoceptors in mouse brain. (1989) (4)
- Calcium entry blockade as a mechanism for chlordimeform-induced inhibition of motor activity in the isolated guinea-pig ileum. (1992) (4)
- Inhibition of gamma-[3H]aminobutyric acid uptake by organotin compounds in vitro. (1985) (4)
- Receptor Binding Techniques in Neurotoxicology (1988) (4)
- Environmental Factors in Neurodegenerative Disorders (2015) (3)
- In Vitro Approaches to Developmental Neurotoxicity (2011) (3)
- Paraoxonase 2 deficiency in mice alters motor behavior and causes region-specific transcript changes in the brain. (2021) (3)
- Paraoxonase 2 (PON2) polymorphisms and Parkinson's disease (2004) (3)
- The Role of Glia in Neurotoxicity, Second Edition (2004) (3)
- The role of protein kinase C alpha and epsilon isozymes in DNA synthesis induced by muscarinic receptors in a glial cell line. (1998) (3)
- In Vitro Neurotoxicology (2011) (3)
- Interaction of sigma-compounds with receptor-stimulated phosphoinositide metabolism in the rat brain. (1990) (3)
- Long-lasting microencephaly following exposure to cocaine during the brain growth spurt in the rat. (1995) (3)
- Toxicology of Pesticides (1987) (3)
- Developmental exposure to diesel exhaust upregulates transcription factor expression, decreases hippocampal neurogenesis, and alters cortical lamina organization: relevance to neurodevelopmental disorders (2020) (3)
- Neurotoxicity of air pollution: Role of neuroinflammation (2019) (3)
- Central Nervous System Toxicity Biomarkers (2019) (3)
- Measurements of neuronal apoptosis. (2011) (3)
- Inhibition of cholinergic muscarinic signaling by ethanol: Potential mechanism of developmental neurotoxicity and biological plausibility for the beneficial effects of choline supplementation (2013) (3)
- Antinociceptive effect of diisopropylphosphofluoridate: development of tolerance and lack of cross-tolerance to morphine. (1985) (3)
- The birth and early years of INA, the International Neurotoxicology Association. (2013) (2)
- Pharmacological Modulation of Brain Nicotinic Binding Sites (1988) (2)
- Evaluation of in vitro neurotoxicity of methyl mercury, PCB153 and PCB126 (2006) (2)
- Guanine nucleotide- and muscarinic agonist-dependent phosphoinositide metabolism in synaptoneurosomes from cerebral cortex of immature rats (1992) (2)
- Interaction of Formamidine Pesticides with Brain α2-Adrenoceptors: in vitro and in vivo Studies in Mice (1989) (2)
- Gene-Environment Interactions (2006) (2)
- Interaction of ethanol and anoxia with muscarinic receptor--stimulated phosphoinositide metabolism during brain development. (1995) (2)
- Manifestations of Neurotoxicity in Occupational Diseases (2020) (2)
- Developmental Exposure to Metals and its Contribution to Age-Related Neurodegeneration (2017) (2)
- Application of a radioactivity detector to the analysis of 14C‐Carmoisine metabolites by ion‐pair high‐pressure liquid chromatography (1984) (2)
- Identification of m3, m4, m5 subtypes of muscarinic receptor mRNA in human blood mononuclear cells (1995) (1)
- Interaction of choline with muscarine receptor-stimulated phosphoinositide metabolism in the rat brain (1986) (1)
- Biochemical and Molecular Neurotoxicology (2004) (1)
- CHAPTER 67 – Paraoxonase (PON1) and Detoxication of Nerve Agents (2009) (1)
- Paraoxonase 1 (PONl) status in risk assessment for organophosphate exposure and pharmacokinetics (2012) (1)
- Development of tolerance to the antinociceptive effect but not to the toxicity of trimethyltin after repeated exposure. (1983) (1)
- Smoking and Nicotine (2014) (1)
- Cholinergic muscarinic receptors as targets for neurotoxicity (2002) (1)
- Effects of gestational and lactational exposure to PCB126 and methylmercury on circulating steroid hormone levels at weaning and puberty in the rat (2007) (1)
- Nutraceuticals in CNS diseases (2016) (1)
- The Muscarinic Receptor-Stimulated Phosphoinositide Metabolism as a Potential Target for the Neurotoxicity of Ethanol During Brain Development (1993) (1)
- Perspectives in PON1 Research (2002) (1)
- Contaminants in fish: Risk–benefit considerations (2006) (1)
- Chapter 14 – Ontogeny of Second Messenger Systems (1998) (1)
- Neurotoxicity of amitraz, a formamidine pesticide (2020) (1)
- Cell Signaling and Neurotoxicity (2010) (1)
- Paraoxonase (PON1), detoxification of nerve agents, and modulation of their toxicity (2020) (1)
- Modulation of Neuritogenesis by Astrocyte (2008) (1)
- Neurobehavioural effects induced by perinatal or postnatal exposure to a polybrominated diphenyl ether (PBDE 99). Are they due to different times of exposure, or to differences in administration procedure? (2003) (1)
- Role of Glia in MPTP Toxicityand Parkinson’s Disease (2004) (1)
- Inhibitors of Na/K-ATPase stimulate phosphoinositide metabolism in rat brain (1988) (1)
- Organophosphates and Carbamates (2014) (1)
- Modulation of fibronectin expression in astrocytes affects neuritogenesis (2012) (1)
- Are there muscarinic receptors on erythrocyte membranes (1983) (1)
- Signal Transduction and Neurotoxicity: What Can We Learn from Experimental Culture Systems? (2011) (1)
- Paraoxonase (PON1) and Detoxication of Nerve Agents (2015) (1)
- MUSCARINIC RECEPTORS AND THE DEVELOPING NERVOUS SYSTEM 2 (1993) (1)
- Gene-EnvironmentFundamentals of Ecogenetics (2006) (1)
- Receptors and Ion Channels (2006) (0)
- Prenatal exposure effects of repeated oral dose of domoic acid on neurobehavior in mice (2013) (0)
- Alternative Methodologies in Toxicology (2008) (0)
- Teratology (2006) (0)
- An interview with Lucio G. Costa and Michael Aschner, section editors for toxicology (2012) (0)
- Ethanol interferes with the trophic action of NMDA and carbachol, but not with that of forskolin and gaba, on cultured cerebellar granule neurons undergoing apoptosis (1998) (0)
- Sheldon D. Murphy. (2000) (0)
- Neurotoxicology (2004) (0)
- Nutraceuticals in central nervous system diseases: potential mechanisms of neuroprotection (2021) (0)
- Agrochemicals: A Brief Overview (2018) (0)
- Shotgun proteomics implicates extracellular matrix proteins and protease systems in neuronal development induced by astrocyte cholinergic stimulation: Astrocyte secretome and neuronal development (2010) (0)
- Genetic variability factors in human susceptibility to organophosphorus compounds (2010) (0)
- Neurotoxicology (2005) (0)
- Toxicological Models (2007) (0)
- MECHANISMS OF TOLERANCE TO ANTICHOLINESTERASE INSECTICIDE TOXICITY (1983) (0)
- Teratology (2005) (0)
- Biochemical and Molecular Neurotoxicology (2009) (0)
- Biochemical and Molecular Neurotoxicology (2004) (0)
- Neurotoxicology (2003) (0)
- Molecular mechanisms involved in experimental microencephaly (1990) (0)
- [The effect of pesticides-CDM and AMZ on inhibition of the binding of 3H-clonidine to alpha 2-adrenoreceptor in rat forebrain tissue]. (1990) (0)
- Is PKC a target for ethanol in alcohol-induced arrest of muscarinic receptor-mediated glial cell growth? (1997) (0)
- Styrene-induced glutathione depletion in rat brain. effects of ethanol (1992) (0)
- Toxicology of Metals (2014) (0)
- Changes in brain monoamine oxidase B in rat exposed to styrene (1998) (0)
- Analytical Cytology: Applications to Neurotoxicology (2000) (0)
- Metabolism and Toxicity of Occupational Neurotoxicants: Genetic, Physiological, and Environmental Determinants (2020) (0)
- Respiratory tract alterations in rats exposed to styrene by inhalation or injection route (1996) (0)
- Alternative Methodologies in Toxicology (2007) (0)
- Activation of muscarinic receptors induces proliferation of rat cortical astrocytes and human astrocytoma cells: Role of protein kinase C (1995) (0)
- Demeton-S-methyl. (1997) (0)
- Chapter 8 PONt AND ORGANOPHOSPHATE TOXICITY (0)
- Two subtypes of enteric non-opioid sigma receptors in guinea-pig cholinergic motor neurons. (1991) (0)
- Paraoxonase (PON1) Gene Polymorphisms (2004) (0)
- Toxicological Models (2009) (0)
- Methylmercury Neurotoxicity: A Synopsis of In Vitro Effects (2012) (0)
- Morphological and Biochemical Aspects of Triphenyl Tin Hepatotoxicity in Rats (1989) (0)
- Methylmercury Neurotoxicity: A Synopsis of In Vitro Effects (2012) (0)
- | The Role of Glia in Neurotoxicity | Taylor & Francis Group (2004) (0)
- Ethanol inhibits carbachol-induced calcium responses in glial cells in a concentration- and time-dependent manner (1998) (0)
- Neurotoxicology (2008) (0)
- Alternative Methodologies in Toxicology (2011) (0)
- Environmental Factors in Neurodevelopmental Disorders (2015) (0)
- Neurotoxicity of acute diesel exhaust exposure in adult mice (2015) (0)
- Biomarkers in Occupational Neurotoxicology (2020) (0)
- Role of Occupational Neurotoxicants in Psychiatric and Neurodegenerative Disorders (2020) (0)
- Monitoring styrene neurotoxicity with 3H-spiperone binding in lymphocytes (1990) (0)
- The role of glutathione in the detoxification of chlorpyrifos and methyl chlorpyrifos in mice (1981) (0)
- Paraoxonase, Butyrylcholinesterase, and Epoxide Hydrolase (2006) (0)
- transporter gene (SLC6A3), pesticide exposure and Parkinson's disease risk: a hypothesis-generating (2006) (0)
- Prenatal Ethanol Exposure UpRegulates the Cholesterol Transporters ATP-Binding Cassette A 1 and G 1 and Reduces Cholesterol Levels in the Developing Rat Brain (2014) (0)
- The metabotropic glutamate receptors Edited by P. Jeffrey Conn and Jitendra Patel Humana Press, Totowa, NJ, 1994, pp. 277, ISBN 0-89603-291-4, US$99.50 (1996) (0)
- Chapter 57 – Disruption of Cholesterol Homeostasis in Developmental Neurotoxicity (2017) (0)
- Occupatinal Neurotoxicology (2020) (0)
- Effects of paraoxonase-1 (PON1) status on pre- and postnatal exposures to chlorpyrifos oxon and diazoxon (2014) (0)
- Teratology (1869) (0)
- Alternative Methodologies in Toxicology (2007) (0)
- Gastrointestinal Toxicology (2010) (0)
- Running Title: Maternal PON1 modulates fetal toxicity of chlorpyrifos oxon (2014) (0)
- Mutations in Human PON1: Role in Organophosphorus Sensitivity and Vascular Disease (2000) (0)
- Alternative Methodologies in Toxicology (2008) (0)
- The muscarinic receptor-coupled phosphoinositide metabolism as a potential target for the developmental neurotoxicity of aliphatic alcohols (1990) (0)
- G-proteins- and muscarinic receptor-dependent phosphoinositide metabolism in neonatal rat brain (1992) (0)
- Overview of Section III (2006) (0)
- [Oncogenes as indicators of occupational exposure to carcinogenic agents]. (1993) (0)
- Teratology (2006) (0)
- Biochemical and molecular neurotoxicology: Relevance to neurotoxicity testing and risk assessment (1998) (0)
- [Role of genetic polymorphism in risk assessment]. (2003) (0)
- In vivo ethanol decreases phosphorylated MAPK and p70S6 kinase in the developing rat brain (2003) (0)
- Biochemical and Molecular Neurotoxicology (2010) (0)
- Uptake, metabolism and excretion of (14C)-carmosine in rats (1980) (0)
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