Ludmil Alexandrov
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Bioengineering scientist
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Ludmil Alexandrovbiology Degrees
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Ludmil Alexandrovengineering Degrees
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Biology Engineering
Why Is Ludmil Alexandrov Influential?
(Suggest an Edit or Addition)According to Wikipedia, Ludmil B. Alexandrov is a Bulgarian-American scientist and an assistant professor at the University of California, San Diego. Education Alexandrov received his PhD from University of Cambridge in 2014.
Ludmil Alexandrov's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Signatures of mutational processes in human cancer (2013) (7589)
- The repertoire of mutational signatures in human cancer (2018) (1656)
- Mutational Processes Molding the Genomes of 21 Breast Cancers (2012) (1622)
- Landscape of somatic mutations in 560 breast cancer whole genome sequences (2016) (1574)
- Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets (2015) (1253)
- The Life History of 21 Breast Cancers (2012) (1180)
- The Evolutionary History of Lethal Metastatic Prostate Cancer (2015) (1150)
- High burden and pervasive positive selection of somatic mutations in normal human skin (2015) (1127)
- Deciphering Signatures of Mutational Processes Operative in Human Cancer (2013) (981)
- Whole-genome landscapes of major melanoma subtypes (2017) (875)
- Heterogeneity of genomic evolution and mutational profiles in multiple myeloma (2014) (743)
- Clock-like mutational processes in human somatic cells (2015) (729)
- Mutational signatures associated with tobacco smoking in human cancer (2016) (722)
- Subclonal diversification of primary breast cancer revealed by multiregion sequencing (2015) (656)
- Whole-Genome and Epigenomic Landscapes of Etiologically Distinct Subtypes of Cholangiocarcinoma. (2017) (515)
- Pan-cancer genome and transcriptome analyses of 1,699 pediatric leukemias and solid tumors (2018) (506)
- Genomic Evolution of Breast Cancer Metastasis and Relapse (2017) (457)
- Timing, rates and spectra of human germline mutation (2015) (455)
- Mutational signatures: the patterns of somatic mutations hidden in cancer genomes (2014) (400)
- Analysis of the Genetic Phylogeny of Multifocal Prostate Cancer Identifies Multiple Independent Clonal Expansions in Neoplastic and Morphologically Normal Prostate Tissue (2015) (399)
- A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns (2016) (399)
- Patterns of somatic structural variation in human cancer genomes (2020) (377)
- Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer (2014) (358)
- Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer (2014) (358)
- Intra-tumour diversification in colorectal cancer at the single-cell level (2018) (341)
- Tracking the origins and drivers of subclonal metastatic expansion in prostate cancer (2015) (322)
- RAG-mediated recombination is the predominant driver of oncogenic rearrangement in ETV6-RUNX1 acute lymphoblastic leukemia (2013) (301)
- Genome sequencing of normal cells reveals developmental lineages and mutational processes (2014) (297)
- Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers (2015) (295)
- Genome Sequencing and Analysis of the Tasmanian Devil and Its Transmissible Cancer (2012) (292)
- Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes (2014) (289)
- Association of a germline copy number polymorphism of APOBEC3A and APOBEC3B with burden of putative APOBEC-dependent mutations in breast cancer (2014) (248)
- Characterizing Mutational Signatures in Human Cancer Cell Lines Reveals Episodic APOBEC Mutagenesis (2019) (242)
- Integrative genomic profiling of large-cell neuroendocrine carcinomas reveals distinct subtypes of high-grade neuroendocrine lung tumors (2018) (210)
- Mutational signatures of ionizing radiation in second malignancies (2016) (207)
- Association of Distinct Mutational Signatures With Correlates of Increased Immune Activity in Pancreatic Ductal Adenocarcinoma (2017) (205)
- Somatic mutations reveal asymmetric cellular dynamics in the early human embryo (2017) (204)
- The topography of mutational processes in breast cancer genomes (2016) (198)
- Comprehensive molecular characterization of mitochondrial genomes in human cancers (2017) (197)
- Mutation allele burden remains unchanged in chronic myelomonocytic leukaemia responding to hypomethylating agents (2016) (175)
- The Life History of 21 Breast Cancers (2015) (173)
- The genomic landscape of cutaneous SCC reveals drivers and a novel azathioprine associated mutational signature (2018) (172)
- Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets (2018) (169)
- The genome as a record of environmental exposure (2015) (161)
- Recurrent mutation of IGF signalling genes and distinct patterns of genomic rearrangement in osteosarcoma (2017) (157)
- C. elegans whole-genome sequencing reveals mutational signatures related to carcinogens and DNA repair deficiency (2014) (155)
- A mutational signature in gastric cancer suggests therapeutic strategies (2015) (145)
- Transmissible Dog Cancer Genome Reveals the Origin and History of an Ancient Cell Lineage (2014) (142)
- SETD2 loss-of-function promotes renal cancer branched evolution through replication stress and impaired DNA repair (2015) (140)
- A Specific Mutational Signature Associated with DNA 8-Oxoguanine Persistence in MUTYH-defective Colorectal Cancer (2017) (139)
- Therapy-induced mutations drive the genomic landscape of relapsed acute lymphoblastic leukemia. (2019) (137)
- Genomic patterns of progression in smoldering multiple myeloma (2018) (135)
- SigProfilerMatrixGenerator: a tool for visualizing and exploring patterns of small mutational events (2019) (111)
- Inactivating CUX1 mutations promote tumorigenesis (2013) (111)
- Mammalian Stem Cells Reprogramming in Response to Terahertz Radiation (2010) (110)
- Rearrangement bursts generate canonical gene fusions in bone and soft tissue tumors (2018) (108)
- Mutational signature analysis identifies MUTYH deficiency in colorectal cancers and adrenocortical carcinomas (2017) (102)
- Precancer Atlas to Drive Precision Prevention Trials. (2017) (98)
- The driver landscape of sporadic chordoma (2017) (96)
- Germline MC1R status influences somatic mutation burden in melanoma (2016) (92)
- Understanding mutagenesis through delineation of mutational signatures in human cancer. (2016) (90)
- Specificity and Heterogeneity of Terahertz Radiation Effect on Gene Expression in Mouse Mesenchymal Stem Cells (2013) (85)
- The Origins and Vulnerabilities of Two Transmissible Cancers in Tasmanian Devils (2018) (80)
- APOBEC mutation drives early-onset squamous cell carcinomas in recessive dystrophic epidermolysis bullosa (2018) (80)
- Syngeneic animal models of tobacco-associated oral cancer reveal the activity of in situ anti-CTLA-4 (2019) (77)
- Nonnegative/Binary matrix factorization with a D-Wave quantum annealer (2017) (76)
- Timing the initiation of multiple myeloma (2019) (76)
- IL-17 signaling in steatotic hepatocytes and macrophages promotes hepatocellular carcinoma in alcohol-related liver disease. (2019) (73)
- Non-thermal effects of terahertz radiation on gene expression in mouse stem cells (2011) (69)
- Biological and prognostic impact of APOBEC-induced mutations in the spectrum of plasma cell dyscrasias and multiple myeloma cell lines (2017) (68)
- Undifferentiated Sarcomas Develop through Distinct Evolutionary Pathways (2019) (68)
- A somatic-mutational process recurrently duplicates germline susceptibility loci and tissue-specific super-enhancers in breast cancers (2017) (67)
- A nonlinear dynamic model of DNA with a sequence-dependent stacking term (2009) (60)
- Modelling the magnetic signature of neuronal tissue (2007) (59)
- Uncovering novel mutational signatures by de novo extraction with SigProfilerExtractor (2020) (58)
- Integrative genomic analysis of mouse and human hepatocellular carcinoma (2018) (57)
- The mutational signature profile of known and suspected human carcinogens in mice (2020) (55)
- Base changes in tumour DNA have the power to reveal the causes and evolution of cancer (2016) (54)
- DNA dynamics play a role as a basal transcription factor in the positioning and regulation of gene transcription initiation (2009) (54)
- Somatic evolution and global expansion of an ancient transmissible cancer lineage (2019) (52)
- Strength of immune selection in tumors varies with sex and age (2020) (51)
- Signatures of copy number alterations in human cancer (2021) (48)
- Mutational signatures in tumours induced by high and low energy radiation in Trp53 deficient mice (2020) (45)
- Genomic evidence supports a clonal diaspora model for metastases of esophageal adenocarcinoma (2018) (45)
- Mutational signatures in esophageal squamous cell carcinoma from eight countries with varying incidence (2021) (45)
- Uracil Accumulation and Mutagenesis Dominated by Cytosine Deamination in CpG Dinucleotides in Mice Lacking UNG and SMUG1 (2017) (44)
- Genomic and evolutionary classification of lung cancer in never smokers (2021) (43)
- Whole-exome sequencing of cervical carcinomas identifies activating ERBB2 and PIK3CA mutations as targets for combination therapy (2019) (43)
- Sex differences in oncogenic mutational processes (2019) (41)
- Fast randomization of large genomic datasets while preserving alteration counts (2014) (37)
- Partially methylated domains are hypervariable in breast cancer and fuel widespread CpG island hypermethylation (2018) (37)
- Mapping clustered mutations in cancer reveals APOBEC3 mutagenesis of ecDNA (2022) (34)
- Integrated mutational landscape analysis of uterine leiomyosarcomas (2021) (33)
- Germline determinants of the somatic mutation landscape in 2,642 cancer genomes (2017) (33)
- Understanding the origins of human cancer (2015) (31)
- The Clonal Evolution of Metastatic Osteosarcoma as Shaped by Cisplatin Treatment (2019) (31)
- Binding of Nucleoid-Associated Protein Fis to DNA Is Regulated by DNA Breathing Dynamics (2013) (29)
- Mechanisms of APOBEC3 mutagenesis in human cancer cells (2022) (25)
- Revertant mosaicism repairs skin lesions in a patient with keratitis-ichthyosis-deafness syndrome by second-site mutations in connexin 26 (2017) (24)
- Signatures of mutational processes in human cancer this access benefits you. Your matters (2013) (23)
- Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples (2020) (22)
- St. Jude Cloud-a Pediatric Cancer Genomic Data Sharing Ecosystem. (2021) (21)
- Analysis of mutational signatures in exomes from B-cell lymphoma cell lines suggest APOBEC3 family members to be involved in the pathogenesis of primary effusion lymphoma (2015) (20)
- Lineage-defined leiomyosarcoma subtypes emerge years before diagnosis and determine patient survival (2021) (20)
- Inhibition of mTOR signaling and clinical activity of metformin in oral premalignant lesions (2021) (19)
- A phase 2 evaluation of pembrolizumab for recurrent Lynch‐like versus sporadic endometrial cancers with microsatellite instability (2021) (19)
- Immune evasion in HPV− head and neck precancer–cancer transition is driven by an aneuploid switch involving chromosome 9p loss (2021) (17)
- A phase II evaluation of pembrolizumab in recurrent microsatellite instability-high (MSI-H) endometrial cancer patients with Lynch-like versus MLH-1 methylated characteristics (NCT02899793). (2021) (17)
- Corrigendum: Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue (2015) (16)
- Generating realistic null hypothesis of cancer mutational landscapes using SigProfilerSimulator (2020) (16)
- Whole-exome sequencing reveals the impact of UVA light mutagenesis in xeroderma pigmentosum variant human cells (2019) (16)
- Abstract IA11: Signatures of mutational processes in human cancer (2017) (15)
- Stem cell replication, somatic mutations and role of randomness in the development of cancer (2019) (15)
- Corrigendum: Signatures of mutational processes in human cancer (2013) (13)
- The genomic and epigenomic evolutionary history of papillary renal cell carcinomas (2018) (12)
- Insights into BRCA Cancer Predisposition from Integrated Germline and Somatic Analyses in 7632 Cancers (2019) (11)
- Inflammation-driven deaminase deregulation fuels human pre-leukemia stem cell evolution. (2021) (10)
- Author Correction: Landscape of somatic mutations in 560 breast cancer whole-genome sequences (2019) (10)
- Unraveling the genomic landscape of colorectal cancer through mutational signatures. (2021) (9)
- Evaluating the role of coherent delocalized phonon-like modes in DNA cyclization (2017) (8)
- Tracing Lung Cancer Risk Factors Through Mutational Signatures in Never-Smokers. (2020) (8)
- Homologous recombination deficiency (HRD) signature-3 in ovarian and uterine carcinosarcomas correlates with preclinical sensitivity to Olaparib, a poly (adenosine diphosphate [ADP]- ribose) polymerase (PARP) inhibitor. (2022) (8)
- R-loop homeostasis and cancer mutagenesis promoted by the DNA cytosine deaminase APOBEC3B (2021) (7)
- Significance and limitations of the use of next-generation sequencing technologies for detecting mutational signatures. (2021) (7)
- Mutational Signatures and the Etiology of Human Cancers (2018) (6)
- DNA Dynamics Is Likely to Be a Factor in the Genomic Nucleotide Repeats Expansions Related to Diseases (2011) (6)
- The APOBEC3A deaminase drives episodic mutagenesis in cancer cells (2021) (6)
- 537 Accelerated endogenous mutation rate drives early-onset squamous cell carcinomas in recessive dystrophic epidermolysis bullosa (2017) (5)
- Examining clustered somatic mutations with SigProfilerClusters (2022) (5)
- Integrative genomic profiling of large-cell neuroendocrine carcinomas reveals distinct subtypes of high-grade neuroendocrine lung tumors (2018) (5)
- Erratum: The Life History of 21 Breast Cancers (Cell 149 (994-1007)) (2015) (5)
- Erratum: A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns (2016) (5)
- Bioinformatic Methods to Identify Mutational Signatures in Cancer. (2021) (5)
- Supplementary file 3. (2014) (4)
- The Association of Modifiable Breast Cancer Risk Factors and Somatic Genomic Alterations in Breast Tumors: The Cancer Genome Atlas Network (2020) (4)
- Supplementary file 1. (2015) (4)
- Control-independent mosaic single nucleotide variant detection with DeepMosaic. (2023) (3)
- A genetic model for central chondrosarcoma evolution correlates with patient outcome (2021) (3)
- An overview of mutational and copy number signatures in human cancer (2022) (3)
- Comprehensive analysis of mutational signatures in pediatric cancers (2021) (3)
- Generating realistic null hypothesis of cancer mutational landscapes using SigProfilerSimulator (2020) (3)
- The role of structural parameters in DNA cyclization (2016) (3)
- Topography of mutational signatures in human cancer (2022) (3)
- 604 Cancer Genomics, Epigenetics and Genomic Instability. Mutational Processes Shaping the Genomes of Twenty-one Breast Cancers (2012) (2)
- Extrachromosomal DNA in the cancerous transformation of Barrett’s oesophagus (2022) (2)
- Supplementary file 2. (2014) (2)
- Imetelstat Inhibits Telomerase and Prevents Propagation of ADAR1-Activated Myeloproliferative Neoplasm and Leukemia Stem Cells (2020) (2)
- Author Correction: The repertoire of mutational signatures in human cancer (2020) (2)
- Computer Modeling Describes Gravity-Related Adaptation in Cell Cultures (2009) (2)
- Synergistic activity of neratinib in combination with olaparib in uterine serous carcinoma overexpressing HER2/neu. (2022) (2)
- Author Correction: The evolutionary history of lethal metastatic prostate cancer (2020) (2)
- Comprehensive analysis of clustered mutations in cancer reveals recurrent APOBEC3 mutagenesis of ecDNA (2021) (2)
- Abstract 4322: The landscape of mitochondrial DNA mutations in human cancer (2014) (2)
- Supplementary File 4 (2014) (1)
- Disentangling heterogeneity of Malignant Pleural Mesothelioma through deep integrative omics analyses (2021) (1)
- The genomic landscape of cutaneous SCC reveals drivers and a novel azathioprine associated mutational signature (2018) (1)
- Somatic mutational profiles and germline polygenic risk scores in human cancer (2021) (1)
- 1 DISTINCT MUTATIONAL SIGNATURES ARE ASSOCIATED WITH CORRELATES OF 1 INCREASED IMMUNE ACTIVITY IN PANCREATIC DUCTAL ADENOCARCINOMA 2 3 (2016) (1)
- Unraveling the impact of a germline heterozygous POLD1 frameshift variant in serrated polyposis syndrome (2023) (1)
- Germline TP53 mutations undergo copy number gain years prior to tumor diagnosis (2023) (1)
- Correction: DNA Dynamics Is Likely to Be a Factor in the Genomic Nucleotide Repeats Expansions Related to Diseases (2011) (1)
- Author Correction: Landscape of somatic mutations in 560 breast cancer whole-genome sequences (2019) (1)
- Corrigendum: A somatic-mutational process recurrently duplicates germline susceptibility loci and tissue-specific super-enhancers in breast cancers (2017) (1)
- Author Correction: Pan-cancer analysis of whole genomes (2023) (1)
- Synchronous, Yet Genomically Distinct, GIST Offer New Insights Into Precise Targeting of Tumor Driver Mutations. (2021) (1)
- Somatic 9p24.1 alterations in HPV– head and neck squamous cancer dictate immune microenvironment and anti-PD-1 checkpoint inhibitor activity (2022) (1)
- Abstract SY26-02: Sherlock-Lung: Tracing lung cancer mutational processes in never smokers (2019) (1)
- Abstract 1319: Distinct pancancer mutational signatures are determined byAPOBEC/ADARaberrations (2020) (0)
- G05 : Exome sequencing of 243 liver tumors identifies new mutational signatures and potential therapeutic targets (2015) (0)
- Abstract 956: The evolutionary history of lethal metastatic prostate cancer (2015) (0)
- Abstract 2318: The association between somatic mutational profiles and germline polygenic risk scores in TCGA (2020) (0)
- Abstract SY26-02:Sherlock-Lung: Tracing lung cancer mutational processes in never smokers (2019) (0)
- BAY1895344, a novel ataxia telangiectasia and RAD3-related (ATR) inhibitor, is active in vivo against ATRX mutated uterine leiomyosarcoma (212) (2022) (0)
- Abstract P5-08-07: Tobacco use, alcohol consumption, and breast cancer somatic genomic alterations (2020) (0)
- Mechanisms of APOBEC3 mutagenesis in human cancer cells (2022) (0)
- P1.08-A Sherlock Lung Tracing Lung Cancer Mutational Processes in Never-smokers (2019) (0)
- signatures related to carcinogens and DNA repair deficiency whole genome sequencing reveals mutational (2014) (0)
- Genomic evidence supports a clonal diaspora model for metastases of esophageal adenocarcinoma (2020) (0)
- Abstract A009: Benchmarking the foreign antigen space of human malignancies (2016) (0)
- Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets (2018) (0)
- TBIO-04. Comprehensive analysis of mutational signatures in pediatric cancers (2022) (0)
- Tubio retrotransposition in cancer genomes Extensive transduction of nonrepetitive DNA mediated by L 1 (2014) (0)
- 1818 Evolution from primary breast cancer to relapse and metastasis (2015) (0)
- SigProfilerMatrixGenerator: a tool for visualizing and exploring patterns of small mutational events (2019) (0)
- Chromosomal fragile site breakage by EBV-encoded EBNA1 at clustered repeats (2023) (0)
- Supplementary information Inactivating CUX1 mutations promote tumorigenesis (2013) (0)
- Abstract 3130: Extrachromosomal DNA in the cancerous transformation of Barrett’s esophagus (2023) (0)
- Ovarian and uterine carcinosarcomas are sensitive in vitro and in vivo to elimusertib, a novel ataxia-telangiectasia and Rad3-related (ATR) kinase inhibitor. (2022) (0)
- Unwinding the mutational signatures of a DNA topoisomerase enzyme (2022) (0)
- MP49-06 GENOMIC ANALYSIS OF MULTIPLE PROSTATE CANCER METASTASES HIGHLIGHTS METASTASIS FROM LOW-GRADE CANCER FOCI AND DYNAMIC ADAPTATIONS TO THERAPY (2014) (0)
- MP49-01 SUBCLONAL ORIGIN OF PROSTATE CANCER METASTASIS WITH MUTATOR PHENOTYPE FROM A NOVEL MSH2 GENE FUSION (2014) (0)
- The genomic and epigenomic evolutionary history of papillary renal cell carcinomas (2020) (0)
- Visualizing and exploring patterns of large mutational events with SigProfilerMatrixGenerator (2023) (0)
- The architecture of clonal expansions in morphologically normal tissue from cancerous and non-cancerous prostates (2022) (0)
- Author Correction: Inferring structural variant cancer cell fraction (2022) (0)
- Genomic Evolution of Brea st Cancer Metastasis and Relapse Graphical (0)
- Randomisation of next generation sequencing data while preserving genomic event distributions (2012) (0)
- Whole Exome Sequencing Of Multiple Myeloma Reveals An Heterogeneous Clonal Architecture and Genomic Evolution (2013) (0)
- NIHMS662581-supplement-Supplementary data (2016) (0)
- Author Correction: The evolutionary history of 2,658 cancers (2023) (0)
- AI-assisted discovery of an ethnicity-influenced driver of cell transformation in esophageal and gastroesophageal junction adenocarcinomas (2022) (0)
- Abstract B51: Novel syngeneic animal model of tobacco-associated oral cancer reveals the activity of in situ anti-CTLA-4 (2020) (0)
- Thank you to eBioMedicine's clinical and statistical peer reviewers in 2022 (2023) (0)
- Acknowledgment of Reviewers, 2018 (2018) (0)
- Supplementary file 6. (2014) (0)
- The driver landscape of sporadic chordoma (2017) (0)
- Comprehensive analysis of mutational signatures reveals distinct patterns and molecular processes across 27 pediatric cancers (2023) (0)
- Multiomic analysis of malignant pleural mesothelioma identifies molecular axes and specialized tumor profiles driving intertumor heterogeneity (2023) (0)
- Ovarian and uterine carcinosarcoma cell lines show preclinical sensitivity to BAY 1895344, a novel ataxia-telangiectasia and Rad3-related (ATR) kinase inhibitor (011) (2022) (0)
- Murchison of an Ancient Cell Lineage Transmissable Dog Cancer Genome Reveals the Origin and History (2014) (0)
- Novel syngeneic animal model of tobacco-associated oral cancer reveals the activity of in situ anti-CTLA-4 (2019) (0)
- OA04.05 MESOMICS Project: Using Whole-Genome Sequencing Data to Fill the Gaps in Malignant Pleural Mesothelioma Molecular Studies (2022) (0)
- IL-17 Signaling in Steatotic Hepatocytes and Macrophages Promotes Alcoholic Liver Disease-induced Hepatocellular Carcinoma (2020) (0)
- 122 Mutational landscape of highly malignant recessive dystrophic epidermolysis bullosa-associated squamous cell carcinoma (2017) (0)
- Inflammatory Cytokine Responsive Enzymatic Mutagenesis Fuels Myeloproliferative Neoplasm Pre-Leukemia Stem Cell Evolution (2019) (0)
- Benchmarking the Foreign Antigen Space of Human Malignancies (2018) (0)
- Lineage-defined leiomyosarcoma subtypes emerge years before diagnosis and determine patient survival (2021) (0)
- Tracking clonal diversity in metastatic prostate cancer progression. (2015) (0)
- Clonal Diaspora in Metastatic Esophageal Adenocarcinoma Describes a New Model of Cancer Progression (2018) (0)
- Author Correction: DNA damage and somatic mutations in mammalian cells after irradiation with a nail polish dryer (2023) (0)
- New Insights into Protein-DNA Binding from Simulations of DNA Breathing Dynamics (2013) (0)
- From copy number alterations to structural variants: the evolutionary cascade of papillary renal cell carcinomas (2018) (0)
- Signatures of copy number alterations in human cancer (2022) (0)
- Abstract 2506: Exploring the complex etiology of oncogenic fusions in childhood cancer (2019) (0)
- Evaluating the role of coherent delocalized phonon-like modes in DNA cyclization (2017) (0)
- Timing the initiation of multiple myeloma (2020) (0)
- EP007/#994 Bay 1895344, a novel ATR inhibitor, demonstrates in vivo activity against ATRX altered uterine leiomyosarcoma (2022) (0)
- Partially methylated domains are hypervariable in breast cancer and fuel widespread CpG island hypermethylation (2019) (0)
- Mutational Signature Mark Cancer’s Smoking Gun (2016) (0)
- Somatic mutational profiles and germline polygenic risk scores in human cancer (2022) (0)
- Uracil Accumulation and Mutagenesis Dominated by Cytosine Deamination in CpG Dinucleotides in Mice Lacking UNG and SMUG1 (2017) (0)
- Supplementary file 5. (2014) (0)
- Mitotic tethering enables en masse inheritance of a shattered micronuclear chromosome (2022) (0)
- Abstract 1166: APOBEC deaminases compete with tobacco smoking mutagenesis and affect age at onset of lung cancer (2023) (0)
- Abstract 2198: The impact of carcinogens, obesity, and chronic inflammatory processes on mutational signatures and cancer risk in mouse tumor models (2022) (0)
- Arsenic is a potent co-mutagen of ultraviolet light (2023) (0)
- Abstract B09: DNA polymerase mutations trigger rapid onset of ultra-hypermutant malignant brain tumors in children with biallelic mismatch repair deficiency (2015) (0)
- Genomic patterns of progression in smoldering multiple myeloma (2018) (0)
- Author Correction: Patterns of somatic structural variation in human cancer genomes (2020) (0)
- Title A mutational signature in gastric cancer suggests therapeuticstrategies (2015) (0)
- Abstract 865: Genomic and evolutionary classification of lung cancer in never smokers from the Sherlock-Lungstudy (2021) (0)
- Author Correction: Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples (2020) (0)
- Genomic evidence supports a clonal diaspora model for metastases of esophageal 1 adenocarcinoma 2 3 (2019) (0)
- Unexpected complexity in the origins of prostate cancer metastases (2015) (0)
- GE-09COMBINED HEREDITARY AND SOMATIC MUTATIONS OF REPLICATION ERROR REPAIR GENES RESULT IN RAPID ONSET OF ULTRA-HYPERMUTATED MALIGNANT BRAIN TUMORS IN CHILDREN (2015) (0)
- Deep learning predicts HRD and platinum response from histology slides in breast and ovarian cancer (2023) (0)
- Intra-tumour diversification in colorectal cancer at the single-cell level (2018) (0)
- DNA damage and somatic mutations in mammalian cells after irradiation with a nail polish dryer (2021) (0)
- Abstract 2973: Exome sequencing of 243 liver tumors identifies new mutational signatures and potential therapeutic targets (2015) (0)
- Whole genome sequencing of 2,023 colorectal cancers reveals mutational landscapes, new driver genes and immune interactions (2022) (0)
- The mutational signature profile of known and suspected human carcinogens in mice (2020) (0)
- The role of structural parameters in DNA cyclization (2016) (0)
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