Lynn Corcoran
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Lynn Corcoran's Degrees
- Masters Computer Science Stanford University
- Bachelors Computer Science University of California, Berkeley
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(Suggest an Edit or Addition)According to Wikipedia, Lynn Corcoran is an American–Australian immunologist who is Professor of Immunology at the Walter and Eliza Hall Institute. Her research considers cancer, parasitology and immunology, with a focus on B cells biology. She was inducted into the Victorian government's Honour Roll in 2013.
Lynn Corcoran's Published Works
Published Works
- The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice (1985) (1744)
- The generation of antibody-secreting plasma cells (2015) (939)
- IL-21 regulates germinal center B cell differentiation and proliferation through a B cell–intrinsic mechanism (2010) (719)
- The POU domain: a large conserved region in the mammalian pit-1, oct-1, oct-2, and Caenorhabditis elegans unc-86 gene products. (1988) (677)
- Genetic analysis of the human malaria parasite Plasmodium falciparum. (1987) (674)
- Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control TH2 responses (2009) (574)
- Bcl-2 Can Rescue T Lymphocyte Development in Interleukin-7 Receptor–Deficient Mice but Not in Mutant rag-1 −/− Mice (1997) (552)
- Plasma Cell Ontogeny Defined by Quantitative Changes in Blimp-1 Expression (2004) (517)
- Cytokine-Mediated Regulation of Human B Cell Differentiation into Ig-Secreting Cells: Predominant Role of IL-21 Produced by CXCR5+ T Follicular Helper Cells1 (2007) (484)
- Functional immunoglobulin transgenes guide ordered B-cell differentiation in Rag-1-deficient mice. (1994) (474)
- The B-cell-specific Oct-2 protein contains POU box- and homeo box-type domains. (1988) (350)
- Murine T lymphomas in which the cellular myc oncogene has been activated by retroviral insertion (1984) (329)
- Transcriptional repressor Blimp-1 is essential for T cell homeostasis and self-tolerance (2006) (316)
- Virus-transformed pre-B cells show ordered activation but not inactivation of immunoglobulin gene rearrangement and transcription (1991) (304)
- Transcriptional profiling of mouse B cell terminal differentiation defines a signature for antibody-secreting plasma cells (2015) (295)
- Cellular myc oncogene is altered by chromosome translocation to an immunoglobulin locus in murine plasmacytomas and is rearranged similarly in human Burkitt lymphomas. (1983) (276)
- Initiation of plasma-cell differentiation is independent of the transcription factor Blimp-1. (2007) (271)
- Plasma cell development and survival (2010) (267)
- Oct-2, although not required for early B-cell development, is critical for later B-cell maturation and for postnatal survival. (1993) (259)
- Class-Switch Recombination Occurs Infrequently in Germinal Centers. (2019) (256)
- The Lymphoid Past of Mouse Plasmacytoid Cells and Thymic Dendritic Cells1 (2003) (226)
- Evidence from the generation of immunoglobulin G–secreting cells that stochastic mechanisms regulate lymphocyte differentiation (2004) (215)
- The genetic network controlling plasma cell differentiation. (2011) (206)
- Homologous recombination within subtelomeric repeat sequences generates chromosome size polymorphisms in P. falciparum (1988) (204)
- B and T cells collaborate in antiviral responses via IL-6, IL-21, and transcriptional activator and coactivator, Oct2 and OBF-1 (2012) (185)
- Size variation in chromosomes from independent cultured isolates of Plasmodium falciparum (1985) (184)
- Structure of the RESA gene of Plasmodium falciparum. (1986) (177)
- Chromosome size polymorphisms in plasmodium falciparum can involve deletions and are frequent in natural parasite populations (1986) (170)
- Bcl-2 expression promotes B- but not T-lymphoid development in scid mice (1994) (169)
- Immunization of Aotus monkeys with recombinant proteins of an erythrocyte surface antigen of Plasmodium falciparum (1986) (168)
- Variant (6;15) translocations in murine plasmacytomas involve a chromosome 15 locus at least 72 kb from the c‐myc oncogene. (1985) (156)
- Monocytic leukemia zinc finger protein is essential for the development of long-term reconstituting hematopoietic stem cells. (2006) (151)
- Identification of Pax5 Target Genes in Early B Cell Differentiation1 (2008) (131)
- Repression of Flt3 by Pax5 is crucial for B-cell lineage commitment. (2006) (129)
- The linkage between T‐cell and dendritic cell development in the mouse thymus (1998) (123)
- A Myc-dependent division timer complements a cell-death timer to regulate T cell and B cell responses (2016) (122)
- B cell development and immunoglobulin gene transcription in the absence of Oct-2 and OBF-1 (2001) (117)
- The transcription factors IRF8 and PU.1 negatively regulate plasma cell differentiation (2014) (116)
- Molecular karyotype of Plasmodium falciparum: conserved linkage groups and expendable histidine-rich protein genes. (1987) (114)
- CD93 is required for maintenance of antibody secretion and persistence of plasma cells in the bone marrow niche (2009) (114)
- High Rate of Antibody Secretion Is not Integral to Plasma Cell Differentiation as Revealed by XBP-1 Deficiency (2012) (111)
- Oct-2 is required early in T cell-independent B cell activation for G1 progression and for proliferation. (1994) (109)
- Transcription Factor IRF4 Regulates Germinal Center Cell Formation through a B Cell–Intrinsic Mechanism (2014) (107)
- Convergent differentiation: myeloid and lymphoid pathways to murine plasmacytoid dendritic cells. (2013) (99)
- Different Kinetics of Blimp-1 Induction in B Cell Subsets Revealed by Reporter Gene1 (2007) (96)
- The promoter of the human interleukin-2 gene contains two octamer-binding sites and is partially activated by the expression of Oct-2 (1990) (90)
- The BTB-ZF transcription factor Zbtb20 is driven by Irf4 to promote plasma cell differentiation and longevity (2014) (90)
- Haemopedia RNA-seq: a database of gene expression during haematopoiesis in mice and humans (2018) (89)
- Regulation of germinal center responses, memory B cells and plasma cell formation-an update. (2016) (88)
- Fas ligand–mediated immune surveillance by T cells is essential for the control of spontaneous B cell lymphomas (2014) (88)
- Expression of a bcl-2 transgene reduces proliferation and slows turnover of developing B lymphocytes in vivo. (1997) (86)
- The Helix-Loop-Helix Protein ID2 Governs NK Cell Fate by Tuning Their Sensitivity to Interleukin-15. (2016) (86)
- Increased Expression of CD27 on Activated Human Memory B Cells Correlates with Their Commitment to the Plasma Cell Lineage1 (2005) (80)
- Identification of CD36 as the first gene dependent on the B-cell differentiation factor Oct-2. (1995) (80)
- Expression and Purification of Glutathione‐S‐Transferase Fusion Proteins (1994) (80)
- Increased expression of CD27 on activated human memory B cells correlates with their commitment to the plasma cell lineage (2005) (80)
- CD36 Is Differentially Expressed by CD8+ Splenic Dendritic Cells But Is Not Required for Cross-Presentation In Vivo1 (2002) (76)
- Transposition of the immunoglobulin heavy chain enhancer to the myc oncogene in a murine plasmacytoma (1985) (75)
- Normalization of boutique two-color microarrays with a high proportion of differentially expressed probes (2007) (71)
- Oct2 enhances antibody-secreting cell differentiation through regulation of IL-5 receptor α chain expression on activated B cells (2008) (70)
- Differential transactivation potential of Oct1 and Oct2 is determined by additional B cell‐specific activities. (1994) (68)
- Germline-activating mutations in PIK3CD compromise B cell development and function (2018) (64)
- The Wellcome Trust Lecture: Genes for antigens of Plasmodium falciparum (1986) (63)
- Differential requirement for OBF-1 during antibody-secreting cell differentiation (2005) (63)
- A high throughput embryonic stem cell screen identifies Oct-2 as a bifunctional regulator of neuronal differentiation. (2009) (63)
- oct-2 gene disruption eliminates the peritoneal B-1 lymphocyte lineage and attenuates B-2 cell maturation and function. (1997) (60)
- Defined Blocks in Terminal Plasma Cell Differentiation of Common Variable Immunodeficiency Patients1 (2005) (56)
- Regression of devil facial tumour disease following immunotherapy in immunised Tasmanian devils (2017) (54)
- An Inducible Enhancer Required for Il12b Promoter Activity in an Insulated Chromatin Environment (2007) (50)
- Dynamic changes in Id3 and E-protein activity orchestrate germinal center and plasma cell development (2016) (48)
- PU.1 cooperates with IRF4 and IRF8 to suppress pre-B-cell leukemia (2016) (48)
- MiR-210 Is Induced by Oct-2, Regulates B Cells, and Inhibits Autoantibody Production (2013) (48)
- Attenuation of TCR-induced transcription by Bach2 controls regulatory T cell differentiation and homeostasis (2020) (47)
- The Ets factor Spi-B is a direct critical target of the coactivator OBF-1. (2006) (45)
- Development of murine plasmacytoid dendritic cell subsets (2005) (45)
- Transcription Factor PU.1 Promotes Conventional Dendritic Cell Identity and Function via Induction of Transcriptional Regulator DC‐SCRIPT (2019) (43)
- Continued differentiation during B lymphopoiesis requires signals in addition to cell survival. (1997) (42)
- RUNX2 Mediates Plasmacytoid Dendritic Cell Egress from the Bone Marrow and Controls Viral Immunity. (2016) (42)
- PD-L1 Is Not Constitutively Expressed on Tasmanian Devil Facial Tumor Cells but Is Strongly Upregulated in Response to IFN-γ and Can Be Expressed in the Tumor Microenvironment (2016) (40)
- A second antigenic heat shock protein of Plasmodium falciparum. (1988) (39)
- BTB‐ZF transcription factors, a growing family of regulators of early and late B‐cell development (2014) (37)
- Identification of dendritic cells, B cell and T cell subsets in Tasmanian devil lymphoid tissue; evidence for poor immune cell infiltration into devil facial tumors (2014) (36)
- IL4 and IL21 cooperate to induce the high Bcl6 protein level required for germinal center formation (2017) (33)
- Enhanced cell survival and tumorigenesis. (1994) (32)
- Immunology of a Transmissible Cancer Spreading among Tasmanian Devils (2015) (31)
- Defined blocks in terminal plasma cell differentiation of common variable immunodeficiency patients (2006) (31)
- NFκB1 is essential to prevent the development of multiorgan autoimmunity by limiting IL-6 production in follicular B cells (2016) (31)
- Immunization Strategies Producing a Humoral IgG Immune Response against Devil Facial Tumor Disease in the Majority of Tasmanian Devils Destined for Wild Release (2018) (30)
- Oct-2 regulates CD36 gene expression via a consensus octamer, which excludes the co-activator OBF-1. (2002) (29)
- IL-5 and Rp105 signaling defects in B cells from commonly used 129 mouse substrains. (1999) (28)
- Family-specific differences in transcription efficiency of Ig heavy chain promoters. (1997) (27)
- Id2 and E Proteins Orchestrate the Initiation and Maintenance of MLL-Rearranged Acute Myeloid Leukemia. (2016) (26)
- Oct2 and Obf1 as Facilitators of B:T Cell Collaboration during a Humoral Immune Response (2014) (25)
- Differential regulation of CD36 expression in antigen-presenting cells: Oct-2 dependence in B lymphocytes but not dendritic cells or macrophages. (2002) (25)
- Two of a kind: transmissible Schwann cell cancers in the endangered Tasmanian devil (Sarcophilus harrisii) (2019) (23)
- Mitogen‐activated Tasmanian devil blood mononuclear cells kill devil facial tumour disease cells (2016) (21)
- High-Affinity B Cell Receptor Ligation by Cognate Antigen Induces Cytokine-Independent Isotype Switching (2010) (20)
- GM-CSF produced by recombinant vaccinia virus or in GM-CSF transgenic mice has no effect in vivo on murine cutaneous leishmaniasis. (1988) (20)
- Germinal center‐independent, IgM‐mediated autoimmunity in sanroque mice lacking Obf1 (2014) (19)
- Silencing and Nuclear Repositioning of the λ5 Gene Locus at the Pre-B Cell Stage Requires Aiolos and OBF-1 (2008) (19)
- All Known In Vivo Functions of the Oct-2 Transcription Factor Require the C-Terminal Protein Domain1 (2004) (18)
- Blimp1 is limiting for transformation in a mouse plasmacytoma model. (2009) (17)
- Onecut Factors and Pou2f2 Regulate the Distribution of V2 Interneurons in the Mouse Developing Spinal Cord (2018) (16)
- Generation of B lymphoma cell lines from knockout mice by transformation in vivo with an Emu-myc transgene. (1999) (16)
- c-myc-induced lymphomagenesis in transgenic mice and the role of the Pvt-1 locus in lymphoid neoplasia. (1986) (14)
- The toll‐like receptor ligands Hiltonol® (polyICLC) and imiquimod effectively activate antigen‐specific immune responses in Tasmanian devils (Sarcophilus harrisii) (2017) (13)
- Transcriptome and proteome profiling reveals stress-induced expression signatures of imiquimod-treated Tasmanian devil facial tumor disease (DFTD) cells (2018) (12)
- Mining the Plasma Cell Transcriptome for Novel Cell Surface Proteins (2018) (12)
- The myc oncogene and lymphoid neoplasia: from translocations to transgenic mice. (1987) (9)
- Activation of the c-myc oncogene in B and T lymphoid tumors. (1984) (9)
- Long-Lived Plasma Cells Have a Sweet Tooth. (2016) (9)
- Expression of parasite antigens in Escherichia coli. (1987) (8)
- Transcriptional control of B cell activation. (2005) (6)
- Pou2f2 Regulates the Distribution of Dorsal Interneurons in the Mouse Developing Spinal Cord (2019) (6)
- Nerve growth factor-regulated properties of sensory neurones in Oct-2 null mutant mice. (1995) (5)
- Lessons from Translocations and Transgenic Mice: Constitutive c-myc Expression Predisposes to Neoplasia (1986) (5)
- T Follicular Helper Cells + CXCR 5 Predominant Role of IL-21 Produced by Cell Differentiation into Ig-Secreting Cells : Cytokine-Mediated Regulation of Human B and (2007) (4)
- Generation of novel Id2 and E2-2, E2A and HEB antibodies reveals novel Id2 binding partners and species-specific expression of E-proteins in NK cells. (2019) (3)
- Chromosomes of Plasmodium falciparum. (1986) (2)
- Characterisation of CD4 T cells in healthy and diseased koalas (Phascolarctos cinereus) using cell-type-specific monoclonal antibodies. (2016) (2)
- Knockout B lymphoma cell lines as biochemical tools to explore multiple signalling pathways (2003) (2)
- Transcription factors in B-cell development and function (2000) (1)
- Zbtb20 identifies and controls a thymus-derived population of regulatory T cells that play a role in intestinal homeostasis (2022) (1)
- Attenuation of TCR-induced transcription by Bach2 controls regulatory T cell differentiation and homeostasis (2020) (1)
- The flavors of plasma cells (2015) (1)
- What the papers say: Molecular karyotypes: Separating chromosomes on gels (1985) (1)
- Molecular karyotypes: separating chromosomes on gels. (1985) (1)
- SCID mice reconstituted with Oct-2-deficient lymphocytes can cure Leishmania major infection and generate normal antigen-specific T cells. (1995) (1)
- ThePromoter oftheHumanInterleukin-2 GeneContains Two Octamer-Binding Sites andIsPartially Activated bythe Expression ofOct-2 (1990) (0)
- Dendritic cells: differentiation (WS-046) Chairpersons: Kayo Inaba, Laszlo Nagy (2010) (0)
- The role of Blimp-1 in lymphocyte terminal differentiation and homeostasis (2005) (0)
- Specific expression of a BTB-ZF transcription factor defines innate-like regulatory T cells that are essential for intestinal homeostasis (2021) (0)
- In Vivo Splenic Dendritic Cells But Is Not Required + CD 36 Is Differentially Expressed by CD 8 (2002) (0)
- Protein Domain C-TerminalTranscription Factor Require the All Known In Vivo Functions of the Oct-2 (2004) (0)
- Transcriptional control (SY4-4) Chairpersons: Toshinori Nakayama, Ellen Rothenberg (2010) (0)
- Corrigendum: B cell development and immunoglobulin gene transcription in the absence of Oct-2 and OBF-1 (2006) (0)
- Cytokine-Independent Isotype Switching Cognate Antigen Induces High-Affinity B Cell Receptor Ligation by (2010) (0)
- Spreading among Tasmanian Devils Immunology of a Transmissible Cancer (2015) (0)
- plasmacytoid dendritic cells Convergent differentiation: myeloid and lymphoid pathways to murine (2014) (0)
- Germinal center reaction (PP-031) (2010) (0)
- The development, turnover rate and maturation status of dendritic cells and Langerhans cells (2003) (0)
- Nucleic Acids Research (2016) (0)
- Cells and Thymic Dendritic Cells The Lymphoid Past of Mouse Plasmacytoid (0)
- Expression of a BTB-ZF transcription factor controls the function of an innate-like Tregs essential for intestinal homeostasis (2022) (0)
- Syddansk Universitet Regression of devil facial tumour disease following immunotherapy in immunised (2017) (0)
- Plasma cell differentiation (WS-050) Chairpersons: Takeshi Tokuhisa, Stephen Nutt (2010) (0)
- Erratum: Increased expression of CD27 on activated human memory B cells correlates with their commitment to the plasma cell lineage (Journal of Immunology (2005) 174 (4034-4042)) (2005) (0)
- Revealed by XBP-1 Deficiency Integral to Plasma Cell Differentiation as High Rate of Antibody Secretion Is not (2012) (0)
- Cells, and Inhibits Autoantibody Production MiR-210 Is Induced by Oct-2, Regulates B (2013) (0)
- Pathogenic germline activating mutations in PIK3CD intrinsically compromise B-cell development and function, underlying humoral defects in human primary immunodeficiency (2018) (0)
- Mouse Substrains IL-5 and Rp 105 Signaling Defects in B Cells (1999) (0)
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