Michael A. Beaven
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Michael A. Beaven's Degrees
- PhD Biochemistry University of California, Berkeley
- Masters Chemistry Stanford University
- Bachelors Chemistry University of California, Berkeley
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(Suggest an Edit or Addition)Michael A. Beaven's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Resveratrol ameliorates aging-related metabolic phenotypes by inhibiting cAMP phosphodiesterases (2012) (1189)
- Characterization of novel stem cell factor responsive human mast cell lines LAD 1 and 2 established from a patient with mast cell sarcoma/leukemia; activation following aggregation of FcepsilonRI or FcgammaRI. (2003) (476)
- The A3 adenosine receptor is the unique adenosine receptor which facilitates release of allergic mediators in mast cells. (1993) (424)
- Role of ABCC1 in export of sphingosine-1-phosphate from mast cells (2006) (421)
- Ca(2+)-dependent and Ca(2+)-independent isozymes of protein kinase C mediate exocytosis in antigen-stimulated rat basophilic RBL-2H3 cells. Reconstitution of secretory responses with Ca2+ and purified isozymes in washed permeabilized cells. (1993) (364)
- Signal transduction by Fc receptors: the Fc&RI case (1993) (352)
- Modification of the enzymatic isotopic assay of histamine and its application to measurement of histamine in tissues, serum and urine. (1972) (325)
- The mechanism of the calcium signal and correlation with histamine release in 2H3 cells. (1984) (315)
- Increased sensitivity of the enzymatic isotopic assay of histamine: measurement of histamine in plasma and serum. (1979) (297)
- Mitogen-activated protein (MAP) kinase regulates production of tumor necrosis factor-alpha and release of arachidonic acid in mast cells. Indications of communication between p38 and p42 MAP kinases. (1997) (243)
- Increase in cytosolic calcium and phosphoinositide metabolism induced by angiotensin II and [Arg]vasopressin in vascular smooth muscle cells. (1985) (234)
- Regulation of mast cell responses in health and disease. (2011) (233)
- Activation of exocytosis by the heterotrimeric G protein Gi3. (1993) (230)
- Our perception of the mast cell from Paul Ehrlich to now (2009) (200)
- FcepsilonR1 and toll-like receptors mediate synergistic signals to markedly augment production of inflammatory cytokines in murine mast cells. (2006) (196)
- Differential down-regulation of protein kinase C isozymes. (1989) (189)
- Sipple's syndrome: medullary thyroid carcinoma, pheochromocytoma, and parathyroid disease. Studies in a large family. NIH conference. (1973) (188)
- Activation of the mitogen-activated protein kinase/cytosolic phospholipase A2 pathway in a rat mast cell line. Indications of different pathways for release of arachidonic acid and secretory granules. (1995) (187)
- Variable content of histaminase, L-dopa decarboxylase and calcitonin in small-cell carcinoma of the lung. Biologic and clinical implications. (1978) (181)
- The calcium signal and phosphatidylinositol breakdown in 2H3 cells. (1984) (177)
- Activation of phospholipase C via adenosine receptors provides synergistic signals for secretion in antigen-stimulated RBL-2H3 cells. Evidence for a novel adenosine receptor. (1990) (162)
- A microprocedure for the measurement of 14CO2 release from [14C]carboxyl-labeled amino acids. (1978) (153)
- A Requirement for Syk in the Activation of the Microtubule-associated Protein Kinase/Phospholipase A2 Pathway by FcεR1 Is Not Shared by a G Protein-coupled Receptor (*) (1995) (151)
- Different isozymes of protein kinase C mediate feedback inhibition of phospholipase C and stimulatory signals for exocytosis in rat RBL-2H3 cells. (1993) (151)
- Dextran and carrageenan evoke different inflammatory responses in rat with respect to composition of infiltrates and effect of indomethacin. (1982) (151)
- Kit and FcepsilonRI mediate unique and convergent signals for release of inflammatory mediators from human mast cells. (2004) (150)
- Mast cells signal their importance in health and disease. (2018) (150)
- Antigen-induced secretion of histamine and the phosphorylation of myosin by protein kinase C in rat basophilic leukemia cells. (1989) (139)
- Phospholipases D1 and D2 Regulate Different Phases of Exocytosis in Mast Cells (2002) (135)
- Syk-dependent Phosphorylation of Shc (1996) (128)
- Elevated histaminase activity in medullary carcinoma of the thyroid gland. (1970) (119)
- Quantitative relationships between aggregation of IgE receptors, generation of intracellular signals, and histamine secretion in rat basophilic leukemia (2H3) cells. Enhanced responses with heavy water. (1986) (118)
- Activation of the mitogen-activated protein kinase cascade is suppressed by low concentrations of dexamethasone in mast cells. (1996) (115)
- The Phospholipase Cγ1-dependent Pathway of FcϵRI-mediated Mast Cell Activation Is Regulated Independently of Phosphatidylinositol 3-Kinase* (2003) (114)
- Antiproliferative activity of anti-inflammatory drugs in two mammalian cell culture lines. (1977) (110)
- Signal transduction by Fc receptors: the Fc epsilon RI case. (1993) (107)
- Canonical Transient Receptor Potential 5 Channel in Conjunction with Orai1 and STIM1 Allows Sr2+ Entry, Optimal Influx of Ca2+, and Degranulation in a Rat Mast Cell Line1 (2008) (105)
- Btk Plays a Crucial Role in the Amplification of FcϵRI-mediated Mast Cell Activation by Kit* (2005) (98)
- Histaminase activity: a biochemical marker for medullary carcinoma of the thyroid. (1972) (96)
- Amplification of cytokine production through synergistic activation of NFAT and AP‐1 following stimulation of mast cells with antigen and IL‐33 (2011) (93)
- Secretion of TNF from a rat mast cell line is a brefeldin A-sensitive and a calcium/protein kinase C-regulated process. (1994) (93)
- Stem Cell Factor Programs the Mast Cell Activation Phenotype (2012) (93)
- Downstream signals initiated in mast cells by FcεRI and other receptors (1996) (93)
- Secretion from rat basophilic RBL-2H3 cells is associated with diphosphorylation of myosin light chains by myosin light chain kinase as well as phosphorylation by protein kinase C. (1994) (92)
- Compound 48/80 activates mast cell phospholipase D via heterotrimeric GTP-binding proteins. (2000) (91)
- Brain amines and temperature regulation. (1968) (91)
- Curcumin, a constituent of curry, suppresses IgE-mediated allergic response and mast cell activation at the level of Syk. (2008) (88)
- Cutting Edge: Lentiviral Short Hairpin RNA Silencing of PTEN in Human Mast Cells Reveals Constitutive Signals That Promote Cytokine Secretion and Cell Survival1 (2006) (86)
- Dexamethasone Suppresses Antigen-Induced Activation of Phosphatidylinositol 3-Kinase and Downstream Responses in Mast Cells (2004) (86)
- Methods for the analysis of inositol phosphates. (1989) (85)
- The turnover of norepinephrine in thyrotoxic and nonthyrotoxic mice. (1963) (84)
- Regulation of Ca2+ signaling with particular focus on mast cells. (2009) (84)
- Interleukin-33 stimulates formation of functional osteoclasts from human CD14+ monocytes (2010) (81)
- SPECIFIC ALLERGIC SENSITISATION TO FILARIAL ANTIGENS IN TROPICAL EOSINOPHILIA SYNDROME (1979) (81)
- Btk-dependent Rac activation and actin rearrangement following FcεRI aggregation promotes enhanced chemotactic responses of mast cells (2010) (80)
- Arrest of cultured cells in the G1 phase of the cell cycle by indomethacin. (1979) (80)
- Synergistic signals in the mechanism of antigen-induced exocytosis in 2H3 cells: evidence for an unidentified signal required for histamine release (1987) (79)
- Tyrosine phosphorylation of a mitogen-activated protein kinase-like protein occurs at a late step in exocytosis. Studies with tyrosine phosphatase inhibitors and various secretagogues in rat RBL-2H3 cells. (1993) (78)
- Receptor occupation, calcium mobilization, and amylase release in pancreatic acini: effect of CCK-JMV-180. (1989) (78)
- Turnover rates of norepinephrine in hearts of intact mice, rats and guinea pigs using tritiated norepinephrine (1963) (76)
- Prostaglandin E2 Activates and Utilizes mTORC2 as a Central Signaling Locus for the Regulation of Mast Cell Chemotaxis and Mediator Release* (2010) (76)
- Calcium influx in a rat mast cell (RBL-2H3) line. Use of multivalent metal ions to define its characteristics and role in exocytosis. (1991) (75)
- Regulators of Ca(2+) signaling in mast cells: potential targets for treatment of mast cell-related diseases? (2011) (75)
- IL-6 promotes an increase in human mast cell numbers and reactivity through suppression of suppressor of cytokine signaling 3. (2016) (74)
- Evidence that indomethacin reversibly inhibits cell growth in the G1 phase of the cell cycle. (1979) (73)
- Activated mast cells synthesize and release soluble ST2‐a decoy receptor for IL‐33 (2015) (73)
- Membrane phosphoinositide-activated signals in mast cells and basophils. (1988) (72)
- A metabolite of halothane covalently binds to an endoplasmic reticulum protein that is highly homologous to phosphatidylinositol-specific phospholipase C-alpha but has no activity. (1991) (71)
- Sustained activation of phospholipase D via adenosine A3 receptors is associated with enhancement of antigen- and Ca(2+)-ionophore-induced secretion in a rat mast cell line. (1996) (71)
- Quercetin sensitizes RBL-2H3 cells to polybasic mast cell secretagogues through increased expression of Gi GTP-binding proteins linked to a phospholipase C signaling pathway. (1998) (71)
- Turnover and synthesis of diamine oxidase (DAO) in rat tissues. Studies with heparin and cycloheximide. (1976) (71)
- A new assay for histaminase activity: measurement of tritiated water from beta (side chain label)-H 3-histamine. (1971) (68)
- Antigen and thapsigargin promote influx of Ca2+ in rat basophilic RBL-2H3 cells by ostensibly similar mechanisms that allow filling of inositol 1,4,5-trisphosphate-sensitive and mitochondrial Ca2+ stores. (1994) (68)
- Antigen and carbachol mobilize calcium by similar mechanisms in a transfected mast cell line (RBL-2H3 cells) that expresses ml muscarinic receptors. (1993) (67)
- Carbachol induces secretion in a mast cell line (RBL‐2H3) transfected with the ml muscarinic receptor gene (1991) (66)
- The kinetics of phosphoinositide hydrolysis in rat basophilic leukemia (RBL-2H3) cells varies with the type of IgE receptor cross-linking agent used. (1987) (65)
- DJ-1 controls bone homeostasis through the regulation of osteoclast differentiation (2017) (64)
- Chapter Three – Factors Regulating Availability of Histamine at Tissue Receptors (1982) (63)
- Disruption of Raf-1/Heat Shock Protein 90 Complex and Raf Signaling by Dexamethasone in Mast Cells* (2000) (62)
- Membrane IgM, IgD, and IgG act as signal transmission molecules in a series of B lymphomas. (1986) (61)
- IL-33 Induces a Hyporesponsive Phenotype in Human and Mouse Mast Cells (2013) (60)
- New inhibitors of histamine-N-methyltransferase. (1979) (59)
- Studies of protein kinase C in the rat basophilic leukemia (RBL-2H3) cell reveal that antigen-induced signals are not mimicked by the actions of phorbol myristate acetate and Ca2+ ionophore. (1989) (59)
- An Essential Role for Phospholipase D in the Activation of Protein Kinase C and Degranulation in Mast Cells (2005) (58)
- Isolation of Histamine-Containing Cells from Canine Fundic Mucosa (1979) (58)
- BSF-1 action on resting B cells does not require elevation of inositol phospholipid metabolism or increased [Ca2+]i. (1986) (58)
- Cholecystokinin-induced formation of inositol phosphates in pancreatic acini. (1990) (57)
- Influence of indomethacin and other anti-inflammatory drugs on mobilization and production of neutrophils: studies with carrageenan-induced inflammation in rats. (1980) (56)
- METABOLISM OF CHLORPROMAZINE IN HUMANS. (1963) (56)
- Serum histaminase and calcitonin levels in medullary carcinoma of the thyroid. (1972) (55)
- Evidence that prostaglandins do not have a role in the cytostatic action of anti-inflammatory drugs. (1980) (55)
- Histamine: its role in physiological and pathological processes. (1978) (54)
- Constitutive and inducible mechanisms for synthesis and release of cytokines in immune cell lines. (1996) (54)
- Synergistic activation of phospholipases Cgamma and Cbeta: a novel mechanism for PI3K-independent enhancement of FcepsilonRI-induced mast cell mediator release. (2008) (53)
- Stimulated release of histamine by a rat mast cell line is inhibited during mitosis (1984) (53)
- Presence of histamine and histamine-metabolizing enzyme in rat and guinea-pig microvascular endothelial cells. (1982) (53)
- Intracellular pH and free calcium changes in single cells using quene 1 and quin 2 probes and fluorescence microscopy (1983) (52)
- Vasopressin-induced calcium increases in smooth muscle cells from spontaneously hypertensive rats. (1985) (52)
- Phorbol myristate acetate inhibits anti-IgM-mediated signaling in resting B cells. (1986) (50)
- Dexamethasone Up-Regulates the Inhibitory Adaptor Protein Dok-1 and Suppresses Downstream Activation of the Mitogen-Activated Protein Kinase Pathway in Antigen-Stimulated RBL-2H3 Mast Cells (2005) (50)
- Activation of RBL-2H3 Mast Cells Is Dependent on Tyrosine Phosphorylation of Phospholipase D2 by Fyn and Fgr (2004) (49)
- The Phosphoinositide 3-Kinase-Dependent Activation of Btk Is Required for Optimal Eicosanoid Production and Generation of Reactive Oxygen Species in Antigen-Stimulated Mast Cells1 (2008) (48)
- Binding of diamine oxidase activity to rat and guinea pig microvascular endothelial cells. Comparisons with lipoprotein lipase binding. (1985) (48)
- Adenosine A3 receptors in mast cells. (1994) (47)
- The Src Family Kinase Fgr Is Critical for Activation of Mast Cells and IgE-Mediated Anaphylaxis in Mice (2011) (47)
- Assessment of IgE-receptor function through measurement of hydrolysis of membrane inositol phospholipids. New insights on the phenomena of biphasic antigen concentration-response curves and desensitization. (1988) (46)
- Cutting Edge: Dexamethasone Negatively Regulates Syk in Mast Cells by Up-Regulating Src-Like Adaptor Protein1 (2006) (45)
- Antigen activation of mitogen-activated protein kinase in mast cells through protein kinase C-dependent and independent pathways. (1997) (45)
- Mesenteric IL-10-producing CD5+ regulatory B cells suppress cow’s milk casein-induced allergic responses in mice (2016) (45)
- Certain inhibitors of protein serine/threonine kinases also inhibit tyrosine phosphorylation of phospholipase C gamma 1 and other proteins and reveal distinct roles for tyrosine kinase(s) and protein kinase C in stimulated, rat basophilic RBL-2H3 cells. (1992) (44)
- The rise in concentration of free Ca2+ and of pH provides sequential, synergistic signals for secretion in antigen-stimulated rat basophilic leukemia (RBL-2H3) cells. (1989) (44)
- Changes in histamine synthetic activity, histamine content and responsiveness to compound 48/80 with maturation of rat peritoneal mast cells. (1983) (44)
- Anaphylactoid reactions to anesthetic drugs. (1981) (44)
- Response of plasma histaminase activity to small doses of heparin in normal subjects and patients with hyperlipoproteinemia. (1973) (44)
- Modulation of histamine release from canine fundic mucosal mast cells. (1988) (43)
- Selective labeling of histamine in rat gastric mucosa: application to measurement of turnover rate. (1968) (43)
- Elevated Levels of Cyclooxygenase-2 in Antigen-Stimulated Mast Cells Is Associated with Minimal Activation of p38 Mitogen-Activated Protein Kinase (2001) (42)
- Thapsigargin-induced secretion is dependent on activation of a cholera toxin-sensitive and phosphatidylinositol-3-kinase-regulated phospholipase D in a mast cell line. (1998) (42)
- Kit and Fc (cid:1) RI mediate unique and convergent signals for release of inflammatory mediators from human mast cells (2004) (40)
- Dopa decarboxylase in medullary carcinoma of the thyroid. (1973) (39)
- The actions of Ca2+ ionophores on rat basophilic (2H3) cells are dependent on cellular ATP and hydrolysis of inositol phospholipids. A comparison with antigen stimulation. (1987) (39)
- IMPLICATIONS OF UPTAKE AND STORAGE OF NOREPINEPHRINE BY SYMPATHETIC NERVE ENDINGS. (1963) (38)
- A truncated splice-variant of the FcεRIβ receptor subunit is critical for microtubule formation and degranulation in mast cells. (2013) (38)
- Concurrent Inhibition of Kit- and FcϵRI-Mediated Signaling: Coordinated Suppression of Mast Cell Activation (2008) (37)
- DJ-1 regulates mast cell activation and IgE-mediated allergic responses. (2013) (37)
- Treatment with dexamethasone down-regulates IgE-receptor-mediated signals and up-regulates adenosine-receptor-mediated signals in a rat mast cell (RBL-2H3) line. (1990) (37)
- Calcium signalling: Sphingosine kinase versus phospholipase C? (1996) (36)
- The Scaffold Protein Prohibitin Is Required for Antigen-Stimulated Signaling in Mast Cells (2013) (36)
- The CD20 homologue MS4A4 directs trafficking of KIT toward clathrin-independent endocytosis pathways and thus regulates receptor signaling and recycling (2015) (35)
- Mastoparan Selectively Activates Phospholipase D2 in Cell Membranes* (2003) (34)
- A specific and sensitive assay for aminoguanidine: its application to a study of the disposition of aminoguanidine in animal tissues. (1969) (34)
- Study of the relationship of histaminase and diamine oxidase activities in various rat tissues and plasma by sensitive isotopic assay procedures. (1975) (34)
- Btk plays a crucial role in the amplification of Fc epsilonRI-mediated mast cell activation by kit. (2005) (34)
- Regulation of Phospholipase D and Secretion in Mast Cells by Protein Kinase A and Other Protein Kinases (2002) (33)
- Selective labeling and release of nonmast-cell histamine. (1966) (33)
- Receptor-mediated release of inositol 1,4,5-trisphosphate and inositol 1,4-bisphosphate in rat basophilic leukemia RBL-2H3 cells permeabilized with streptolysin O. (1989) (33)
- Downstream signals initiated in mast cells by Fc epsilon RI and other receptors. (1996) (32)
- Formation of inositol 1,4,5-trisphosphate and inositol 1,3,4-trisphosphate from inositol 1,3,4,5-tetrakisphosphate and their pathways of degradation in RBL-2H3 cells. (1988) (32)
- Changes in plasma histaminase activity during normal early human pregnancy and pregnancy disorders. (1975) (32)
- Isolation of histamine-containing cells from rat gastric mucosa: biochemical and morphologic differences from mast cells. (1981) (31)
- Protein kinase C activation blocks anti-IgM-mediated signaling BAL17 B lymphoma cells. (1987) (31)
- Phospholipase D2 acts as an essential adaptor protein in the activation of Syk in antigen-stimulated mast cells. (2006) (31)
- On the mechanism of action of dexamethasone in a rat mast cell line (RBL-2H3 cells). Evidence for altered coupling of receptors and G-proteins. (1990) (30)
- The demonstration of histamine release in clinical conditions: A review of past and present assay procedures (1982) (29)
- Induction of Telomerase Activity During Development of Human Mast Cells from Peripheral Blood CD34+ Cells: Comparisons with Tumor Mast-Cell Lines1 (2001) (29)
- Radiochemical Assay Procedures for Drugs and Transmitters (1975) (28)
- Distribution of histamine and histaminase (diamine oxidase)d in blood of various species. (1980) (28)
- Serine/threonine protein kinases synergistically regulate phospholipase D1 and 2 and secretion in RBL-2H3 mast cells. (2002) (27)
- Examination of the role of TRPM8 in human mast cell activation and its relevance to the etiology of cold-induced urticaria. (2011) (26)
- Stereoselectivity of norepinephrine storage sites in heart. (1964) (26)
- Presence of histaminase and ornithine decarboxylase activities in rat thymus. (1973) (25)
- Gastrin receptors on nonparietal cells isolated from canine fundic mucosa. (1984) (25)
- Synergistic activation of phospholipases Cγ and Cβ: A novel mechanism for PI3K-independent enhancement of FcεRI-induced mast cell mediator release (2009) (25)
- GTP-binding protein G alpha Z: its down-regulation by dexamethasone and its credentials as a mediator of antigen-induced responses in RBL-2H3 cells. (1991) (25)
- Evidence that histamine does not participate in carrageenan-induced pleurisy in rat. (1980) (24)
- The phospholipase C gamma 1-dependent pathway of Fc epsilon RI-mediated mast cell activation is regulated independently of phosphatidylinositol 3-kinase. (2003) (24)
- Phylogeny of histamine in vertebrate brain (1981) (24)
- Loss of secretory response of rat basophilic leukemia (2H3) cells at 40 degrees C is associated with reversible suppression of inositol phospholipid breakdown and calcium signals. (1986) (24)
- Interleukin-10–producing CD5+ B cells inhibit mast cells during immunoglobulin E–mediated allergic responses (2015) (24)
- Knockout of the Trpc1 gene reveals that TRPC1 can promote recovery from anaphylaxis by negatively regulating mast cell TNF-α production. (2013) (23)
- Prevention of F‐actin assembly switches the response to SCF from chemotaxis to degranulation in human mast cells (2013) (22)
- Impromidine, a potent inhibitor of histamine methyltransferase (HMT) and diamine oxidase (DAO). (1980) (22)
- NEUROCHEMICAL TRANSDUCER SYSTEMS. (1963) (22)
- Induction of histidine decarboxylase of rat basophilic leukemia (2H3) cells stimulated by higher oligomeric IgE or phorbol myristate acetate. (1988) (21)
- Concurrent inhibition of kit- and FcepsilonRI-mediated signaling: coordinated suppression of mast cell activation. (2008) (20)
- Uptake and release of 3-H-histamine in cat submaxillary gland. (1967) (20)
- Mechanism of upregulation of the inhibitory regulator, src-like adaptor protein (SLAP), by glucocorticoids in mast cells. (2009) (20)
- Anti-inflammatory drugs alter amino acid transport in HTC cells. (1980) (19)
- Role of calcium, protein kinase C and MAP kinase in the activation of mast cells (1996) (19)
- Histamine synthesis by intact mast cells from canine fundic mucosa and liver (1982) (19)
- Identification of variants of the basophilic leukemia (RBL-2H3) cells that have defective phosphoinositide responses to antigen and stimulants of guanosine 5'-triphosphate-regulatory proteins. (1987) (19)
- Mitogen-activated Protein (MAP) Kinase Regulates Production of Tumor Necrosis Factor-α and Release of Arachidonic Acid in Mast Cells (1997) (19)
- Exon skipping of FcεRIβ eliminates expression of the high-affinity IgE receptor in mast cells with therapeutic potential for allergy (2016) (19)
- Methylxanthines block antigen-induced responses in RBL-2H3 cells independently of adenosine receptors or cyclic AMP: evidence for inhibition of antigen binding to IgE. (1991) (19)
- Paper Chromatography: Multiple Spot Formation by Pure Substances (1960) (19)
- UPTAKE AND RELEASE OF H3-HISTAMINE (1966) (18)
- The effects of L-dopa on in vitro and in vivo calcitonin release from medullary thyroid carcinoma. (1979) (18)
- Rictor Negatively Regulates High-Affinity Receptors for IgE-Induced Mast Cell Degranulation (2014) (16)
- Cloning of the cDNA encoding rat myosin heavy chain-A and evidence for the absence of myosin heavy chain-B in cultured rat mast (RBL-2H3) cells (1996) (16)
- Isolation of histamine-containing cells from canine fundic mucosa. (1979) (16)
- Distinct PGE2-responder and non-responder phenotypes in human mast cell populations: "all or nothing" enhancement of antigen-dependent mediator release. (2011) (16)
- Ornithine decarboxylase and histaminase (diamine oxidase) activities in rat thymus and their relationship to the thymus lymphocyte. (1975) (16)
- Effect of indomethacin on generation of chemotactic activity in inflammatory exudates induced by carrageenan. (1984) (15)
- Histamine synthesis by intact mast cells from canine fundic mucosa and liver. (1982) (14)
- A sensitive and specific tritium release assay for dopamine-β-hydroxylase (DβH) in serum (1976) (13)
- Regulation of Reactive Oxygen Species and the Antioxidant Protein DJ-1 in Mastocytosis (2016) (12)
- Src-like adaptor protein (SLAP) is upregulated in antigen-stimulated mast cells and acts as a negative regulator. (2009) (12)
- Division of labor: specialization of sphingosine kinases in mast cells. (2007) (12)
- Munich Consensus Development Conference on Histamine Determination (1991) (12)
- Mast Cell‐Related Diseases: Genetics, Signaling Pathways, and Novel Therapies (2003) (11)
- The release of tritium upon deamination of 3,4-dihydroxy (2-3H) phenylethylamine by plasma amine oxidase. (1971) (11)
- Enhancement of TNF-alpha synthesis by overexpression of G alpha z in a mast cell line. (1996) (11)
- Histamine synthesis in intact and disrupted rat mast cells. (1982) (11)
- Cardiotoxin from cobra venom increases the level of phosphatidylinositol 4-monophosphate and phosphatidylinositol kinase activity in two cell lines. (1988) (10)
- Factors influencing the uptake and disposition of indomethacin-[14C] in cell cultures. (1980) (10)
- Recognizing the Pleckstrin homology domain fold in mammalian phospholipase D using hidden Markov models (1999) (10)
- Effect of salicylates on histamine and L-histidine metabolism. Inhibition of imidazoleacetate phosphoribosyl transferase. (1976) (9)
- Some observations on aminoguanidine pharmacology. (1970) (9)
- Inhibition of histamine-N-methyltransferase and histaminase (diamine oxidase) by a new histamine H2-receptor agonist, Dimaprit. (1977) (8)
- ROLE OF PHOSPHOLIPASES, PROTEIN KINASES AND CALCIUM IN FcERI- INDUCED SECRETION (1997) (8)
- A novel KIT-deficient mouse mast cell model for the examination of human KIT-mediated activation responses. (2013) (8)
- Histamine in Body Fluids: Its Measurement In Different Clinical States (1984) (8)
- Inhibition of the expression of the "A" system of amino acid transport by anti-inflammatory drugs during cell culture growth and mitogenic stimulation of thymus lymphocytes. (1981) (8)
- Phospholipase D Promotes Lipid Microdomain-Associated Signaling Events in Mast Cells1 (2009) (8)
- Nonselective actions of herbimycin A. (1993) (8)
- Studies with transfected and permeabilized RBL-2H3 cells reveal unique inhibitory properties of protein kinase C gamma. (1994) (8)
- alpha-Fluoromethylhistidine. Kinetics of uptake and inhibition of histamine synthesis in basophil (2H3) cell cultures. (1985) (7)
- Selective labeling of histamine in rat gastric mucosa. (1967) (7)
- Evidence for rapid histamine turnover and loss of histamine from immature rat mast cells. (1986) (7)
- Interaction of DJ‐1 with Lyn is essential for IgE‐mediated stimulation of human mast cells (2017) (7)
- Plenary lecture Mechanism of signal transduction in mast cells and basophils: Studies with RBL-2H3 cells (1987) (6)
- Decline of histidine decarboxylase activity and histamine levels in rat stomach after reserpine. (1971) (6)
- Inhibition of histamine methylation in vivo by the Dimaprit analog, SKF compound 91488 (1979) (6)
- Metabolism of chlorpromazine. (1962) (5)
- The role of myosin phosphorylation in RBL-2H3 cell secretion. (1992) (5)
- Histamine (first of two parts). (1976) (5)
- Changes in histidine uptake and histamine synthesis during the growth cycle of rat basophilic leukemia (2H3) cells. (1985) (5)
- Cytostatic activity of pharmacological concentrations of indomethacin in cell cultures and inactivity of closely related compounds. (1981) (5)
- Mechanism of signal transduction in mast cells and basophils: studies with RBL-2H3 cells. (1987) (4)
- Gel formation with leucocytes and heparin. (1980) (4)
- Histamine (second of two parts). (1976) (3)
- Dexamethasone UpRegulates the Inhibitory Adaptor Protein Dok-1 and Suppresses Downstream Activation of the Mitogen-Activated Protein Kinase Pathway in Antigen-Stimulated RBL-2 H 3 Mast Cells (2005) (3)
- Protein-kinase A and human disease: The core of cAMP-dependent signaling in health and disease (2002) (3)
- The MAP Kinases and Their Role in Mast Cells and Basophils (1999) (3)
- Inflammatory response induced by intrapleural injection of antiserum to IgE in rat. An evaluation of the role of histamine. (1985) (3)
- In situ phosphorylation of human platelet and rat basophilic leukemia cell (RBL-2H3) myosin heavy chain and light chain. (1989) (3)
- Contents, Vol. 8, 1963 (1963) (2)
- The Actions of Ca 2 + Ionophores on Rat Basophilic ( 2 H 3 ) Cells Are Dependent on Cellular ATP and Hydrolysis of Inositol Phospholipids (2001) (2)
- IL-6 promotes an increase in human mast cell number and reactivity through suppression of SOCS3 (2016) (2)
- Radioenzymatic Assays in Biological Fluids (1991) (2)
- The Orchestration of Stimulatory Signals for Secretion in Rat Basophilic Leukemia (RBL-2H3) Cells (1990) (2)
- Relevance of Plasma Histamine Levels to Hypotension (1982) (2)
- Round table discussion on general pharmacology of cimetidine (1978) (2)
- Inositol polyphosphates regulate the membrane interactions of the endosomal p100, G-protein-related protein. (1998) (2)
- Activated Mast Cells Produce Soluble ST2, a Decoy Receptor for IL-33 (2015) (1)
- The Fcεriβ Homologue, MS4A4, Promotes Fcεri-Dependent Human Mast Cell Degranulation By Facilitating PLCγ1 Signaling (2015) (1)
- Phospholipase D and Its Role in Mast Cells (1999) (1)
- Blockade of Antigen Activated Signals by Xanthine Analogs in RBL-2H3 Cells: Evidence for a Novel Adenosine Receptor (1990) (1)
- MS4A4 regulates KIT receptor trafficking, signaling and function in mast cells (HYP3P.343) (2014) (1)
- Fc (cid:1) R1 and toll-like receptors mediate synergistic signals to markedly augment production of inflammatory cytokines in murine mast cells (2005) (1)
- Prostaglandin E2 induces activation of mTORC1 and mTORC2 in mast cells: selective utilization of mTORC2 for the regulation of chemotaxis and mediator release (151.6) (2011) (1)
- The accumulation of H3-serotonin in platelet-free rats. (1970) (1)
- Activation Phenotype Stem Cell Factor Programs the Mast Cell (2012) (1)
- in Human and Mouse Mast Cells IL-33 Induces a Hyporesponsive Phenotype (2012) (0)
- Microdomain-Associated Signaling Events in Phospholipase D Promotes Lipid (2009) (0)
- Receptor Cross-Linkage Stimulates B Cell Activation (1987) (0)
- The nascent truncation of Fc{epsilon}RI{beta} confers calmodulin binding which is essential for microtubule formation and degranulation in human mast cells (2012) (0)
- Phases of Exocytosis in Mast Cells Phospholipases D1 and D2 Regulate Different (2002) (0)
- Constitutive KIT Activity and IL-6 Production in Mast Cells Alters Levels of Reactive Oxygen Species (ROS) and the Scavenger Protein DJ-1 in Mastocytosis (2016) (0)
- Line , and Degranulation in a Rat Mast Cell 2+ Ca Entry, Optimal Influx of 2+ STIM1 Allows Sr Channel in Conjunction with Orai1 and Canonical Transient Receptor Potential 5 (2008) (0)
- Antigen-Stimulated Mast Cells Reactive Oxygen Species in Eicosanoid Production and Generation of Activation of Btk Is Required for Optimal The Phosphoinositide 3-Kinase-Dependent (2008) (0)
- Alteration of tumor-cell growth by anti-inflammatory drugs. Abstr. (1976) (0)
- Estradiol Has a Negative Impact On The Anaphylactic Response In Mice, Independent From Mast Cell Degranulation (2014) (0)
- Up-Regulating Src-Like Adaptor Protein Regulates Syk in Mast Cells by Cutting Edge : Dexamethasone Negatively (2006) (0)
- DegranulationReceptors for IgE-Induced Mast Cell Rictor Negatively Regulates High-Affinity (2014) (0)
- Histamine Cells from Liver Synthesis by Intact Mast Canine Fundic Mucosa and (1982) (0)
- INHIBITION OF IMIDAZOLEACETATE PHOSPHORIBOSYL TRANSFERASE (1976) (0)
- 2119 – CELL MOBILIZATION AND HISTAMINE LEVELS IN RAT PLEURAL EXUDATES PRODUCED BY CARRAGEENAN INJECTION (1978) (0)
- DJ-1 Regulates Bone Homeostasis By Controlling Osteoclastogenesis (2018) (0)
- 4. Role of Calcium, Protein Kinase C and MAP Kinase in the Activation of Mast Cells ( 1 サイトカイン受容体とシグナル伝達) (1995) (0)
- Glucocorticoids Suppress Activation of Mast Cells through induction of Inhibitory Regulators of Signaling Pathways (94.13) (2007) (0)
- The nascent truncation of FcϵRIβ confers calmodulin binding which is essential for microtubule formation and degranulation in human mast cells (177.17) (2012) (0)
- Lantrunculin B-induced filamentous actin disassembly enables human mast cell degranulation by SCF alone (177.7) (2012) (0)
- Contents, Vol. 1, 1968 (1968) (0)
- Binding of diamine oxidase (DAO) and lipoprotein lipase (LPL) to vascular endothelial cells (1984) (0)
- B lymphocyte activation. The roles of receptor cross-linkage and BSF-1. (1987) (0)
- Syk in antigen-stimulated mast cells Phospholipase D2 acts as an essential adaptor protein in the activation of (2013) (0)
- A sensitive and specific tritium release assay for dopamine-beta-hydroxylase (DbetaH) in serum. (1976) (0)
- A flaw in the detection of antigenic sites (1992) (0)
- Cytokine Secretion and Cell Survival Reveals Constitutive Signals That Promote Silencing of PTEN in Human Mast Cells Cutting Edge: Lentiviral Short Hairpin RNA (2006) (0)
- Books received for review (2007) (0)
- THE ROLES OF RECEPTOR CROSS-LINKAGE AND BSF-I (1987) (0)
- Corrigendum to “Characterization of novel stem cell factor responsive human mast cell lines LAD 1 and 2 established from a patient with mast cell sarcoma/leukemia; activation aggregation of FcεRI or FcγRI” [Leuk. Res. 27 (2003) 677–682] (2003) (0)
- Plasma histaminase activity after heparin in normal subjects and patients with hyperlipoproteinemia (1973) (0)
- Subject Index Vol. 2, 1968 (1968) (0)
- FcϵRI-mediated-activation of PLC-γ is not defective in mouse bone marrow-derived mast cells (BMMC) lacking PI-3 kinase-p85α or p85β gene products☆ (2004) (0)
- Mast cells in allergic responses (WS-020) Chairpersons: Susumu Nakae, Chisei Ra (2010) (0)
- Anaphylaxis in Mice Activation of Mast Cells and IgE-Mediated The Src Family Kinase Fgr Is Critical for (2011) (0)
- Histamine production and secretion in rat basophilic leukenia (2H3) cells (1987) (0)
- Stimulatory signals for secretion in a cultured mast cell line: evidence for activation of phospholipase C through more than one G-protein. (1990) (0)
- Chronic IL-33 exposure induces a hypo-responsive mast cell phenotype (177.13) (2012) (0)
- Constitutively Activated KIT in Mastocytosis Patients Is Associated with Decreased Levels of the Scavenger Protein DJ1 and Reciprocal Increases in Reactive Oxygen Species (2015) (0)
- DJ-1 controls bone homeostasis through the regulation of osteoclast differentiation (2017) (0)
- Phospholipase C Signaling Pathway GTP-Binding Proteins Linked toiExpression of G Mast Cell Secretagogues Through Increased Quercetin Sensitizes RBL-2 H 3 Cells to Polybasic (1998) (0)
- Regulation of the Calcium Signal by Phospholipase (PL) D, Sphingosine Kinase (SK), and Phosphatidylinositol 4‐Phosphate (PIP) 5‐Kinase in Mast Cells (2006) (0)
- Discussion of the distribution of serotonin in the nervous system of various animal species. (1968) (0)
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