Mathew Alexander Vadas

Mathew Alexander Vadas's AcademicInfluence.com Rankings

Biology

#7630

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#10580

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Genetics

#734

World Rank

#826

Historical Rank

Molecular Biology

#896

World Rank

#919

Historical Rank

Biochemistry

#1056

World Rank

#1171

Historical Rank

biology Degrees

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Biology

Mathew Alexander Vadas's Degrees

PhD Molecular Biology University of California, Berkeley

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Mathew Alexander Vadas's Published Works

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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1 (2008) (3710)
Stimulation of the adherence of neutrophils to umbilical vein endothelium by human recombinant tumor necrosis factor. (1985) (1006)
Recombinant human interleukin 5 is a selective activator of human eosinophil function (1988) (998)
Stimulation of neutrophils by tumor necrosis factor. (1986) (829)
High-density lipoproteins inhibit cytokine-induced expression of endothelial cell adhesion molecules. (1995) (753)
Recombinant human granulocyte-macrophage colony-stimulating factor stimulates in vitro mature human neutrophil and eosinophil function, surface receptor expression, and survival. (1986) (733)
Activation of sphingosine kinase 1 by ERK1/2‐mediated phosphorylation (2003) (538)
Angiopoietin-1 Is an Antipermeability and Anti-Inflammatory Agent In Vitro and Targets Cell Junctions (2000) (509)
Biologic properties in vitro of a recombinant human granulocyte-macrophage colony-stimulating factor. (1986) (460)
An oncogenic role of sphingosine kinase (2000) (455)
Tumor necrosis factor-alpha induces adhesion molecule expression through the sphingosine kinase pathway. (1998) (423)
A new method for the purification of human eosinophils and neutrophils, and a comparison of the ability of these cells to damage schistosomula of Schistosoma mansoni. (1979) (322)
Cytokines increase human hemopoietic cell adhesiveness by activation of very late antigen (VLA)-4 and VLA-5 integrins (1995) (309)
Activation of Sphingosine Kinase by Tumor Necrosis Factor-α Inhibits Apoptosis in Human Endothelial Cells* (1999) (290)
Characterization of GMP-140 (P-selectin) as a circulating plasma protein (1992) (280)
Phosphorylation-dependent translocation of sphingosine kinase to the plasma membrane drives its oncogenic signalling (2005) (277)
Purified colony-stimulating factors enhance the survival of human neutrophils and eosinophils in vitro: a rapid and sensitive microassay for colony-stimulating factors. (1986) (274)
Hemopoietic colony-stimulating factors. (1984) (256)
Prevention of activated neutrophil adhesion to endothelium by soluble adhesion protein GMP140. (1990) (251)
Sphingosine Kinase Interacts with TRAF2 and Dissects Tumor Necrosis Factor-α Signaling* (2002) (243)
Transendothelial migration of neutrophils involves integrin-associated protein (CD47). (1995) (242)
Endothelial adhesiveness for blood neutrophils is inhibited by transforming growth factor-beta. (1988) (232)
Interleukin-8 induces neutrophil transendothelial migration. (1991) (230)
Activation of antibody-dependent cell-mediated cytotoxicity of human neutrophils and eosinophils by separate colony-stimulating factors. (1983) (225)
Estrogen transactivates EGFR via the sphingosine 1-phosphate receptor Edg-3: the role of sphingosine kinase-1 (2006) (222)
The granulocyte-macrophage colony-stimulating factor/interleukin 3 locus is regulated by an inducible cyclosporin A-sensitive enhancer. (1993) (214)
Transforming growth factor-beta inhibits E-selectin expression on human endothelial cells. (1993) (213)
Factors influencing the ability of HDL to inhibit expression of vascular cell adhesion molecule-1 in endothelial cells. (1998) (207)
Regulation of in vitro capillary tube formation by anti-integrin antibodies (1993) (207)
Ly and Ia antigen phenotypes of T cells involved in delayed-type hypersensitivity and in suppression (1976) (203)
Expression of a Catalytically Inactive Sphingosine Kinase Mutant Blocks Agonist-induced Sphingosine Kinase Activation (2000) (201)
Angiogenesis: models and modulators. (1995) (199)
Stimulation of proliferation, differentiation, and function of human cells by primate interleukin 3. (1987) (197)
High Density Lipoproteins (HDL) Interrupt the Sphingosine Kinase Signaling Pathway (1999) (195)
Hypoxic regulation of vascular endothelial growth factor mRNA stability requires the cooperation of multiple RNA elements. (1999) (190)
Cloning, Characterization, and Chromosomal Location of a Novel Human K+-Cl− Cotransporter* (1999) (187)
Human sphingosine kinase: purification, molecular cloning and characterization of the native and recombinant enzymes. (2000) (184)
Activation of granulocyte cytotoxic function by purified mouse colony-stimulating factors. (1983) (182)
Sphingosine kinase-1 enhances endothelial cell survival through a PECAM-1-dependent activation of PI-3K/Akt and regulation of Bcl-2 family members. (2005) (182)
Requirement for nuclear factor (NF)-kappa B p65 and NF-interleukin-6 binding elements in the tumor necrosis factor response region of the granulocyte colony-stimulating factor promoter. (1994) (171)
H-2 gene complex restricts transfer of delayed-type hypersensitivity in mice. (1975) (170)
Acquisition of murine major histocompatibility complex gene products by schistosomula of Schistosoma mansoni (1978) (170)
Murine eosinophil differentiation factor. An eosinophil-specific colony- stimulating factor with activity for human cells (1986) (168)
Transforming growth factor-beta 1 inhibits the production of IL-8 and the transmigration of neutrophils through activated endothelium. (1996) (167)
High-Density Lipoproteins Neutralize C-Reactive Protein Proinflammatory Activity (2004) (161)
Role of major histocompatibility complex gene products in delayed-type hypersensitivity. (1976) (158)
The role of sphingosine kinase 1 in cancer: oncogene or non-oncogene addiction? (2008) (158)
A radioisotopic method to measure delayed type hypersensitivity in the mouse. I. Studies in sensitized and normal mice. (1975) (155)
Sphingosine kinase transmits estrogen signaling in human breast cancer cells. (2003) (153)
Ability of reconstituted high density lipoproteins to inhibit cytokine-induced expression of vascular cell adhesion molecule-1 in human umbilical vein endothelial cells. (1999) (148)
Dissociation of TNF‐alpha cytotoxic and proinflammatory activities by p55 receptor‐ and p75 receptor‐selective TNF‐alpha mutants. (1994) (145)
GM-CSF, IL-3 and IL-5: cross-competition on human haemopoietic cells. (1992) (143)
Recombinant human tumor necrosis factor-alpha. Regulation of N-formylmethionylleucylphenylalanine receptor affinity and function on human neutrophils. (1988) (140)
Sphingosine kinase interacts with TRAF2 and dissects tumor necrosis factor-alpha signaling. (2002) (138)
A splice-isoform of vesicle-associated membrane protein-1 (VAMP-1) contains a mitochondrial targeting signal. (1998) (134)
Human granulocyte-macrophage colony-stimulating factor enhancer function is associated with cooperative interactions between AP-1 and NFATp/c (1995) (133)
Enhanced helminthotoxic capacity of eosinophils from patients with eosinophilia. (1980) (132)
Recombinant human interleukin-3 and granulocyte-macrophage colony-stimulating factor show common biological effects and binding characteristics on human monocytes. (1989) (129)
Interleukin-5, interleukin-3, and granulocyte-macrophage colony-stimulating factor cross-compete for binding to cell surface receptors on human eosinophils. (1991) (128)
Phospholipid composition of reconstituted high density lipoproteins influences their ability to inhibit endothelial cell adhesion molecule expression. (2000) (127)
Endothelial cell adhesiveness for human T lymphocytes is inhibited by transforming growth factor-beta 1. (1991) (124)
Recruitment and Activation of SHP-1 Protein-tyrosine Phosphatase by Human Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1) (1998) (122)
Localization of the G-CSF gene on chromosome 17 proximal to the breakpoint in the t(15;17) in acute promyelocytic leukemia. (1987) (121)
Short course of systemic corticosteroids in sinonasal polyposis: A double‐blind, randomized, placebo‐controlled trial with evaluation of outcome measures (2008) (118)
Monoclonal antibody 7G3 recognizes the N-terminal domain of the human interleukin-3 (IL-3) receptor alpha-chain and functions as a specific IL-3 receptor antagonist. (1996) (118)
Human Interleukin‐3 inhibits the binding of granulocyte‐macrophage colony‐stimulating factor and interleukin‐5 to basophils and strongly enhances their functional activity (1990) (116)
Differential Regulation of the Stability of Cytokine mRNAs in Lipopolysaccharide-activated Blood Monocytes in Response to Interleukin-10* (1996) (113)
Assessing IRES activity in the HIF-1α and other cellular 5′ UTRs (2006) (113)
Nuclear proteins interacting with the promoter region of the human granulocyte/macrophage colony-stimulating factor gene. (1988) (112)
Reciprocal inhibition of binding between interleukin 3 and granulocyte-macrophage colony-stimulating factor to human eosinophils. (1989) (112)
The Nucleotide-binding Site of Human Sphingosine Kinase 1* (2002) (108)
PPARγ Agonists Ameliorate Endothelial Cell Activation via Inhibition of Diacylglycerol–Protein Kinase C Signaling Pathway: Role of Diacylglycerol Kinase (2004) (106)
Adhesion protein GMP140 inhibits superoxide anion release by human neutrophils. (1991) (105)
Immune evasion by Schistosoma mansoni: loss of susceptibility to antibody or complement-dependent eosinophil attack by schistosomula cultured in medium free of macromolecules (1981) (103)
Short course of systemic corticosteroids in sinonasal polyposis: A double-blind, randomized, placebo-controlled trial with evaluation of outcome measures (2006) (102)
Specific human granulocyte-macrophage colony-stimulating factor antagonists. (1994) (98)
Residue 21 of human granulocyte‐macrophage colony‐stimulating factor is critical for biological activity and for high but not low affinity binding. (1992) (98)
Recombinant human interleukin-3 stimulation of hematopoiesis in humans: loss of responsiveness with differentiation in the neutrophilic myeloid series. (1988) (97)
Studies on the Mechanisms of Immunity in Human Schistosomiasis (1982) (94)
A T cell-specific enhancer in the interleukin-3 locus is activated cooperatively by Oct and NFAT elements within a DNase I-hypersensitive site. (1997) (94)
Primitive human hematopoietic progenitors adhere to P-selectin (CD62P). (1995) (93)
Restoring endocrine response in breast cancer cells by inhibition of the sphingosine kinase-1 signaling pathway. (2009) (92)
A multi-protein complex containing cold shock domain (Y-box) and polypyrimidine tract binding proteins forms on the vascular endothelial growth factor mRNA. Potential role in mRNA stabilization. (2004) (91)
Basal and angiopoietin-1-mediated endothelial permeability is regulated by sphingosine kinase-1. (2008) (90)
Interactions between human eosinophils and schistosomula of schistosoma mansoni. II. The mechanism of irreversible eosinophil adherence (1979) (89)
Signals for activation of the GM-CSF promoter and enhancer in T cells. (1997) (88)
Lumen formation during angiogenesis in vitro involves phagocytic activity, formation and secretion of vacuoles, cell death, and capillary tube remodelling by different populations of endothelial cells (1997) (88)
A model for the interaction of the GM-CSF, IL-3 and IL-5 receptors with their ligands. (1993) (87)
The Protein Tyrosine Phosphatase Pez Is a Major Phosphatase of Adherens Junctions and Dephosphorylates β-Catenin (2003) (87)
The vascular endothelial growth factor mRNA contains an internal ribosome entry site (1998) (85)
Chronic expression of P-selectin on endothelial cells stimulated by the T-cell cytokine, interleukin-3. (1996) (83)
Down‐modulation of receptors for granulocyte colony‐stimulating factor on human neutrophils by granulocyte‐activating agents (1986) (83)
Neutrophils activated by granulocyte-macrophage colony-stimulating factor express receptors for interleukin-3 which mediate class II expression. (1995) (82)
The IIb-IIIa glycoprotein complex that mediates platelet aggregation is directly implicated in leukocyte adhesion (1986) (81)
miR‐181a mediates TGF‐β‐induced hepatocyte EMT and is dysregulated in cirrhosis and hepatocellular cancer (2015) (81)
The cryptome: a subset of the proteome, comprising cryptic peptides with distinct bioactivities. (2006) (80)
The receptor for interleukin 3 is selectively induced in human endothelial cells by tumor necrosis factor alpha and potentiates interleukin 8 secretion and neutrophil transmigration. (1993) (79)
The Calmodulin-binding Site of Sphingosine Kinase and Its Role in Agonist-dependent Translocation of Sphingosine Kinase 1 to the Plasma Membrane* (2006) (78)
Phenoxodiol, an experimental anticancer drug, shows potent antiangiogenic properties in addition to its antitumour effects (2006) (77)
IL-3 and granulocyte-macrophage colony-stimulating factor stimulate two distinct phases of adhesion in human monocytes. (1990) (77)
A new assay for the measurement of the attachment of neutrophils and other cell types to endothelial cells. (1988) (77)
P-selectin interacts with a beta 2-integrin to enhance phagocytosis. (1994) (76)
The detection and initial characterization of colony-stimulating factors in synovial fluid. (1988) (75)
A Proinflammatory Role for Proteolytically Cleaved Annexin A1 in Neutrophil Transendothelial Migration (2010) (75)
Role of protein kinase Czeta in thrombin-induced endothelial permeability changes: inhibition by angiopoietin-1. (2004) (74)
Two contiguous residues in human interleukin-3, Asp21 and Glu22, selectively interact with the alpha- and beta-chains of its receptor and participate in function. (1994) (72)
Activation of the Sphingosine Kinase–Signaling Pathway by High Glucose Mediates the Proinflammatory Phenotype of Endothelial Cells (2005) (71)
Cold shock domain proteins repress transcription from the GM-CSF promoter. (1996) (71)
Loss of sphingosine kinase 1 predisposes to the onset of diabetes via promoting pancreatic β‐cell death in diet‐induced obese mice (2013) (69)
Identification of residues in the first and fourth helices of human granulocyte-macrophage colony-stimulating factor involved in biologic activity and in binding to the alpha- and beta-chains of its receptor. (1994) (67)
Regulation of granulocyte-macrophage colony-stimulating factor and E-selectin expression in endothelial cells by cyclosporin A and the T-cell transcription factor NFAT. (1995) (67)
Phosphorylation of cold shock domain/Y‐box proteins by ERK2 and GSK3β and repression of the human VEGF promoter (2005) (67)
Chemotactic desensitization of neutrophils demonstrates interleukin-8 (IL-8)-dependent and IL-8-independent mechanisms of transmigration through cytokine-activated endothelium. (1993) (65)
Recombinant interleukin 4 stimulates human immunodeficiency virus production by infected monocytes and macrophages. (1992) (64)
A mutation of the common receptor subunit for interleukin-3 (IL-3), granulocyte-macrophage colony-stimulating factor, and IL-5 that leads to ligand independence and tumorigenicity. (1994) (64)
Regulation of human monocyte adherence by granulocyte-macrophage colony-stimulating factor. (1989) (64)
A novel tumor necrosis factor-responsive transcription factor which recognizes a regulatory element in hemopoietic growth factor genes (1990) (64)
Enhancement of human blood eosinophil cytotoxicity by semi-purified eosinophil colony-stimulating factor(s) (1982) (64)
The human granulocyte-macrophage colony-stimulating factor gene is autonomously regulated in vivo by an inducible tissue-specific enhancer. (1999) (63)
Studies on antigen-induced arthritis in mice. III. Cell and serum transfer experiments. (1977) (62)
Enhancement of the intensity, persistence, and passive transfer of delayed-type hypersensitivity lesions by pertussigen in mice (1983) (62)
Stat6 activation is essential for interleukin-4 induction of P-selectin transcription in human umbilical vein endothelial cells. (1999) (62)
Regulation of granulocyte-macrophage colony-stimulating factor and E- selectin expression in endothelial cells by cyclosporin A and the T- cell transcription factor NFAT (1995) (62)
Recombinant human granulocyte-macrophage colony-stimulating factor (rH GM-CSF) regulates f Met-Leu-Phe receptors on human neutrophils. (1988) (58)
IL‐3 receptor expression, regulation and function in cells of the Vasculature. (1996) (58)
Studies on antigen-induced arthritis in mice. II. Immunologic correlates of arthritis susceptibility in mice. (1977) (57)
Novel Cytokine-independent Induction of Endothelial Adhesion Molecules Regulated by Platelet/Endothelial Cell Adhesion Molecule (CD31) (1997) (56)
Synergism between membrane gangliosides and Arg-Gly-Asp-directed glycoprotein receptors in attachment to matrix proteins by melanoma cells (1988) (56)
The protein tyrosine phosphatase Pez is a major phosphatase of adherens junctions and dephosphorylates beta-catenin. (2003) (55)
Eukaryotic Elongation Factor 1A Interacts with Sphingosine Kinase and Directly Enhances Its Catalytic Activity* (2008) (55)
Roles of the N and C Terminal Domains of the Interleukin-3 Receptor α Chain in Receptor Function (1997) (55)
Regulation of vascular leak and recovery from ischemic injury by general and VE-cadherin-restricted miRNA antagonists of miR-27. (2013) (55)
Structure-function studies of human granulocyte-macrophage colony-stimulating factor. Identification of residues required for activity. (1988) (53)
Age-associated stresses induce an anti-inflammatory senescent phenotype in endothelial cells (2013) (52)
A vascular cell-restricted RhoGAP, p73RhoGAP, is a key regulator of angiogenesis. (2004) (52)
Translocation of protein tyrosine phosphatase Pez/PTPD2/PTP36 to the nucleus is associated with induction of cell proliferation. (2000) (51)
ARHGAP18: an endogenous inhibitor of angiogenesis, limiting tip formation and stabilizing junctions (2014) (51)
The effects of recombinant tumour necrosis factor (cachectin) on metabolism in isolated rat adipocyte, hepatocyte and muscle preparations. (1987) (51)
Human tumour necrosis factor-alpha (TNF-alpha) directly stimulates arachidonic acid release in human neutrophils. (1990) (49)
Genetic control of eosinophilia in mice: gene(s) expressed in bone marrow-derived cells control high responsiveness. (1982) (49)
Time sequence of the inhibition of endothelial adhesion molecule expression by reconstituted high density lipoproteins. (2001) (48)
Mononuclear cell-mediated enhancement of granulocyte function in man. (1984) (48)
TGF beta down-regulates TLiSA1 expression and inhibits the differentiation of precursor lymphocytes into CTL and LAK cells. (1989) (48)
Cytolytic T lymphocytes recognize alloantigens on schistosomula of Schistosoma mansoni, but fail to induce damage. (1979) (48)
Eosinophil activation by colony-stimulating factor in man: metabolic effects and analysis by flow cytometry. (1983) (46)
Stress-induced premature senescence mediated by a novel gene, SENEX, results in an anti-inflammatory phenotype in endothelial cells. (2010) (46)
The Human IL-3 Locus Is Regulated Cooperatively by Two NFAT-Dependent Enhancers That Have Distinct Tissue-Specific Activities1 (2002) (45)
Histocompatibility linked immune responsiveness and restrictions imposed on sensitized lymphocytes (1977) (45)
JAM-C Induces Endothelial Cell Permeability Through Its Association and Regulation of &bgr;3 Integrins (2009) (45)
A cytokine receptor gene cluster in the X-Y pseudoautosomal region? (1993) (44)
Synovial fluid neutrophils of patients with rheumatoid arthritis have membrane antigen changes that reflect activation. (1988) (44)
Assessing IRES activity in the HIF-1alpha and other cellular 5' UTRs. (2006) (44)
Interferon-gamma upregulates interleukin-3 (IL-3) receptor expression in human endothelial cells and synergizes with IL-3 in stimulating major histocompatibility complex class II expression and cytokine production. (1995) (44)
Immune reconstitution following peripheral blood stem cell autografting. (1987) (44)
A comparison of eosinophil‐activating factor (EAF) with other monokines and lymphokines (1986) (42)
Sphingosine kinase regulates the rate of endothelial progenitor cell differentiation. (2009) (42)
A novel mechanism of repression of the vascular endothelial growth factor promoter, by single strand DNA binding cold shock domain (Y-box) proteins in normoxic fibroblasts. (2002) (42)
A human interleukin 3 analog with increased biological and binding activities. (1992) (42)
TGF-β and Endothelial Cells Inhibit VCAM-1 Expression on Human Vascular Smooth Muscle Cells (1995) (42)
New frontiers for IL-5. (1997) (41)
Targeting Vascular Endothelial-Cadherin in Tumor-Associated Blood Vessels Promotes T-cell-Mediated Immunotherapy. (2017) (41)
The role of granulocyte-macrophage and granulocyte colony-stimulating factors in neutrophil transendothelial migration: comparison with interleukin-8. (1994) (40)
Transcriptional regulation of mouse granulocyte-macrophage colony-stimulating factor/IL-3 locus. (1995) (40)
Three essential promoter elements mediate tumour necrosis factor and interleukin-1 activation of the granulocyte-colony stimulating factor gene. (1992) (40)
A radioisotopic method to measure delayed type hypersensitivity in the mouse. II. Cell transfer studies. (1975) (40)
Lack of effect of serum amyloid A (SAA) on the ability of high-density lipoproteins to inhibit endothelial cell adhesion molecule expression. (2001) (40)
Mechanism of the interaction mediating killing of Schistosoma mansoni by human eosinophils. (1980) (39)
Interleukin 4 is at 5q31 and interleukin 6 is at 7p15 (1988) (39)
Inhibition of human monocyte adhesion by interleukin-4. (1991) (39)
Studies on the mechanism of the enhancement of delayed-type hypersensitivity by pertussigen. (1984) (39)
Characterization of a spontaneously transformed human endothelial cell line. (1994) (39)
Activation of Endothelial Extracellular Signal-Regulated Kinase Is Essential for Neutrophil Transmigration: Potential Involvement of a Soluble Neutrophil Factor in Endothelial Activation 1 (2003) (38)
Antibody-dependent eosinophil-mediated damage to schistosomula of Schistosoma mansoni: lack of requirement for oxidative metabolism. (1981) (37)
Interleukin 4 and human immunodeficiency virus stimulate LFA-1-ICAM-1-mediated aggregation of monocytes and subsequent giant cell formation. (1994) (37)
Dysregulated hematopoiesis and a progressive neurological disorder induced by expression of an activated form of the human common beta chain in transgenic mice. (1998) (37)
Caveolae control the anti-inflammatory phenotype of senescent endothelial cells (2014) (36)
Tnf modulation of endothelial and neutrophil adhesion (1992) (36)
An assay for sphingosine kinase activity using biotinylated sphingosine and streptavidin-coated membranes. (2004) (36)
Deletion of sphingosine kinase 1 ameliorates hepatic steatosis in diet-induced obese mice: Role of PPARγ. (2016) (36)
ARHGAP18 Protects Against Thoracic Aortic Aneurysm Formation by Mitigating the Synthetic and Proinflammatory Smooth Muscle Cell Phenotype (2017) (35)
Cold Shock Domain Factors Activate the Granulocyte-Macrophage Colony-stimulating Factor Promoter in Stimulated Jurkat T Cells* (2001) (35)
Chronic increases in sphingosine kinase-1 activity induce a pro-inflammatory, pro-angiogenic phenotype in endothelial cells (2009) (34)
Interactions between human eosinophils and schistosomula of Schistosoma mansoni. I. Stable and irreversible antibody-dependent adherence. (1980) (33)
An Ordered Array of Cold Shock Domain Repressor Elements across Tumor Necrosis Factor-responsive Elements of the Granulocyte-Macrophage Colony-stimulating Factor Promoter* (2000) (33)
B1 integrin activation inhibits in vitro tube formation: effects on cell migration, vacuole coalescence and lumen formation. (1999) (33)
Dissociation of TNF- cytotoxic and proinflammatory activities by p55 and p75 receptor-selective TNF- mutants (1994) (32)
Granulocyte-macrophage colony-stimulating factor is a stimulant of platelet-activating factor and superoxide anion generation by human neutrophils. (1991) (32)
Sphingosine kinase 1 is a critical component of the copper-dependent FGF1 export pathway. (2007) (30)
Low fluid shear stress conditions contribute to activation of cerebral cavernous malformation signalling pathways. (2019) (29)
Specific binding of human interleukin-3 and granulocyte-macrophage colony-stimulating factor to human basophils. (1990) (29)
Cyclophosphamide pretreatment induces eosinophilia to nonparasite antigens. (1981) (29)
Human interleukin-3 mRNA accumulation is controlled at both the transcriptional and posttranscriptional level. (1991) (28)
Extracellular truncations of h beta c, the common signaling subunit for interleukin-3 (IL-3), granulocyte-macrophage colony-stimulating factor (GM-CSF), and IL-5, lead to ligand-independent activation. (1996) (28)
The Poly-cistronic miR-23-27-24 Complexes Target Endothelial Cell Junctions: Differential Functional and Molecular Effects of miR-23a and miR-23b. (2016) (27)
The solution structure of the cytokine-binding domain of the common beta-chain of the receptors for granulocyte-macrophage colony-stimulating factor, interleukin-3 and interleukin-5. (2000) (26)
Eosinophilia and acquisition of resistance to Nematospiroides dubius in mice sensitized with adult worms. (1983) (26)
Identification of a human granulocyte functional antigen (GFA-2) involved in antibody-dependent cell-mediated cytotoxicity and phagocytosis. (1985) (25)
The clonal proliferation in vitro of enriched populations of human promyelocytes and myelocytes. (1985) (25)
Nedocromil sodium and cromolyn (sodium cromoglycate) selectively inhibit antibody-dependent granulocyte-mediated cytotoxicity. (1988) (25)
Pertussigen enhances antigen-driven interferon-γ production by sensitized lymphoid cells (1986) (24)
Role of cell surface receptors in the regulation of intracellular killing of bacteria by murine peritoneal exudate neutrophils (1986) (24)
A prospective survey of the incidence of cardiac intoxication with digitalis in patients being admitted to hospital and correlation with serum digoxin levels. (1973) (24)
Regulation of haematopoiesis by growth factors – emerging insights and therapies (2004) (23)
Regulation of the adhesion of neutrophils to endothelium. (1990) (23)
Maturation In Vivo of Schistosoma mansoni Schistosomula After Culture In Vitro with Granulocytes and Antibody (1983) (23)
Depression of immunity to Naegleria fowleri in mice by selective depletion of neutrophils with a monoclonal antibody (1988) (22)
The CCT/TRiC chaperonin is required for maturation of sphingosine kinase 1. (2009) (21)
Endothelial adhesion molecules in atherogenesis. A concerto or a solo? (1996) (21)
Functional studies on purified eosinophils and neutrophils from patients with Schistosoma mansoni infections. (1980) (21)
Therapeutic regulation of VE-cadherin with a novel oligonucleotide drug for diabetic eye complications using retinopathy mouse models (2018) (21)
Regulation of hepatic insulin signaling and glucose homeostasis by sphingosine kinase 2 (2020) (20)
Fc receptors on mouse neutrophils and eosinophils: antigenic characteristics, isotype specificity and relative cell membrane density measured by flow cytometry. (1985) (20)
The RhoGAP protein ARHGAP18/SENEX localizes to microtubules and regulates their stability in endothelial cells (2017) (20)
Regulation of human eosinophil production and function by interleukin-5. (1992) (20)
Bullous pemphigoid blister fluid stimulates eosinophil colony formation and activates eosinophils. (1982) (19)
Potentiation of delayed-type hypersensitivity by pertussigen or cyclophosphamide with release of different lymphokines. (1987) (19)
Expression profiling reveals functionally important genes and coordinately regulated signaling pathway genes during in vitro angiogenesis. (2005) (19)
Sphingosine kinase-1 associates with integrin {alpha}V{beta}3 to mediate endothelial cell survival. (2009) (19)
Eosinophil-mediated killing of schistosomula of Schistosoma mansoni: oxidative requirement for enhancement by eosinophil colony stimulating factor (CSF-alpha) and supernatants with eosinophil cytotoxicity enhancing activity (E-CEA). (1984) (19)
A Discontinuous Eight-Amino Acid Epitope in Human Interleukin-3 Binds the α-Chain of Its Receptor* (1996) (19)
A granulocyte-colony-stimulating factor gene promoter element responsive to inflammatory mediators is functionally distinct from an identical sequence in the granulocyte-macrophage colony-stimulating factor gene. (1991) (19)
The vascular endothelium : structure and function (18)
Roles of the N and C terminal domains of the interleukin-3 receptor alpha chain in receptor function. (1997) (18)
Targeting miR-27a/VE-cadherin interactions rescues cerebral cavernous malformations in mice (2020) (18)
A sequence-specific single-strand DNA binding protein that contacts repressor sequences in the human GM-CSF promoter. (1994) (18)
The Poly-cistronic miR-23-27-24 Complexes Target Endothelial Cell Junctions: Differential Functional and Molecular Effects of miR-23a and miR-23b (2016) (18)
Regulation of granulocyte function by colony stimulating factors. (1984) (17)
Blood leukocytes bind platelet glycoprotein (IIb-IIIa)' but do not express the vitronectin receptor. (1990) (16)
Selective enhancement of the expression of granulocyte functional antigens 1 and 2 on human neutrophils. (1985) (16)
Stimulation of human granulocyte function by monoclonal antibody WEM-G1. (1984) (16)
A point mutant of human sphingosine kinase 1 with increased catalytic activity (2001) (15)
Novel mechanisms of the transendothelial migration of leukocytes. (2001) (14)
Cytokines and allergy. (1994) (14)
Interleukin-3/erythropoietin fusion proteins: in vitro effects on hematopoietic cells. (1993) (14)
Role of colony-stimulating factors in leucocyte responses to inflammation and infection. (1991) (14)
Active subnetwork recovery with a mechanism-dependent scoring function; with application to angiogenesis and organogenesis studies (2013) (13)
REGULATION OF LEUCOCYTE‐ENDOTHELIAL INTERACTIONS OF SPECIAL RELEVANCE TO ATHEROGENESIS (1997) (13)
Antigen activation of T lymphocytes: influence of major histocompatibility complex. (1977) (13)
ARHGAP18: A Flow‐Responsive Gene That Regulates Endothelial Cell Alignment and Protects Against Atherosclerosis (2019) (13)
Heterogeneity of recombinant granulocyte-macrophage colony-stimulating factor-mediated enhancement of neutrophil adherence to endothelium. (1990) (13)
Transmigration of Leukocytes (2001) (13)
TGF-beta and endothelial cells inhibit VCAM-1 expression on human vascular smooth muscle cells. (1995) (12)
Deletion of sphingosine kinase 1 inhibits liver tumorigenesis in diethylnitrosamine-treated mice (2018) (12)
Antigen-initiated B lymphocyte differentiation. IX. Characterization of memory AFC progenitors by buoyant density and sedimentation velocity separation. (1977) (12)
YAP and the RhoC regulator ARHGAP18, are required to mediate flow-dependent endothelial cell alignment (2020) (12)
H-2 LINKED Ir GENE REGULATION OF DELAYED-TYPE HYPERSENSITIVITY IN MICE (1976) (11)
Regulation by the H-2 gene complex of delayed type hypersensitivity (1977) (10)
Differential binding of IL-3 and GM-CSF to human monocytes. (1992) (10)
Nucleotide sequence of the mouse VEGF 3'UTR and quantitative analysis of sites of polyadenylation. (2001) (10)
Mechanisms of eosinophil mediated helminthotoxicity. (1980) (10)
Pertussigen in vivo enhances antigen-specific production in vitro of lymphokine that stimulates macrophage procoagulant activity and plasminogen activator. (1986) (10)
The VE-Cadherin/β-catenin signalling axis regulates immune cell infiltration into tumours. (2020) (9)
Attempts to modify lung granulomatous responses to Schistosoma japonicum eggs in low and high responder mouse strains. (1983) (9)
The effects of markedly raised intracellular sphingosine kinase-1 activity in endothelial cells (2009) (9)
Regulation of human granulocyte function by products derived from murine tumors. (1985) (9)
An autoantibody reactive with nuclei of polymorphonuclear neutrophils: a cell differentiation marker (1981) (8)
The aging endothelium (2021) (8)
Major histocompatibility complex products restrict the adherence of cytolytic T lymphocytes to minor histocompatibility antigens or to trinitrophenyl determinants on schistosomula of Schistosoma mansoni. (1979) (8)
Localization of the human G-CSF gene to the region of a breakpoint in the translocation typical of acute promyelocytic leukemia (1988) (8)
In vitro enhancement of the helminthotoxic capacity of human blood eosinophils. (1981) (8)
Carbohydrate-specific monoclonal antibodies bind to human granulocytes and stimulate antibody-dependent cellular cytotoxicity. (1989) (8)
IL-10 and its homologs: important immune mediators and emerging immunotherapeutic agents (2001) (8)
Synthesis and expression of the gene encoding human interleukin-3. (1989) (7)
Early events in angiogenesis: cloning an alpha-prolyl 4-hydroxylase-like gene. (1998) (7)
The transforming growth factor family and the endothelium (2001) (7)
Differences between virgin and memory IgM-antibody-forming-cell precursor B-cells, and correlations with the heterogeneity present in B-cell populations from unimmunized mice. (1976) (7)
An autoantibody reactive with nuclei of polymorphonuclear neutrophils: a cell differentiation marker. (1981) (7)
Sinusoidal endothelium is essential for liver regeneration (2011) (6)
Regulation of adhesion and adhesion molecules in endothelium by transforming growth factor-beta. (1993) (6)
T-cell functional regions of the human IL-3 proximal promoter. (1994) (6)
Correlation between the stimulation of human neutrophil function by monoclonal antibody and by colony-stimulating factor. (1985) (6)
Human GM-CSF receptor alpha-chain gene is highly polymorphic but not rearranged in AML. (1992) (5)
The Tumour Vasculature as a Target to Modulate Leucocyte Trafficking (2021) (5)
Delayed hypersensitivity induced by anti-T-cell-line antisera is enhanced by pertussigen and not restricted by histocompatibility genes. (1983) (5)
Sphingosine kinase interacts with TRAF2 and dissects tumor necrosis factor-α signaling. (2011) (5)
Major histocompatibility complex gene products on macrophages influence T cell activation. (1978) (5)
[Antigen-induced arthritis in mice: genetic and immunologic studies]. (1978) (4)
Human interleukin 4 regulates the phenotype of lymphocytes generated during mixed lymphocyte culture and inhibits the IL-2-induced development of LAK function in normal and leukaemic cells. (1989) (4)
Selective inhibition of the induction phase of delayed type hypersensitivity in mice by niridazole. (1981) (4)
Comparison of the ability of eosinophils and neutrophils, and of eosinophils from patients with S. mansoni infection and normal individuals, to mediate in vitro damage to schistosomula of S. mansoni. (1979) (4)
Human myeloid growth factors (1987) (4)
Characterisation of a myofibroblast-like cell line from an angiosarcoma. (1996) (4)
Pertussigen enhances antigen-driven interferon-gamma production by sensitized lymphoid cells. (1986) (4)
Sphingosine Kinase-1 Associates with Integrin (cid:1) V (cid:2) 3 to Mediate Endothelial Cell Survival (2009) (3)
Evidence for the control of Eosinophilia by the major histocompatibility complex in mice (2004) (3)
Structure-Function Studies of Lymphokines by Total Chemical Synthesis (1987) (3)
Identification of circulating sphingosine kinase-related metabolites for prediction of type 2 diabetes (2021) (3)
IL-5 and related eosinophilopoietic cytokines: their receptors and their role in eosinophil-mediated inflammatory reactions. (1992) (2)
Peptide insertions in domain 4 of hbeta(c), the shared signalling receptor subunit for GM-CSF, IL3 and IL5, induce ligand-independent activation. (2001) (2)
CHAPTER 20 – Immunological Studies on Schistosomes Cultured in Vitro (1979) (2)
New therapeutic targets in vascular biology (2003) (2)
CHAPTER 16 – Immunological Influences in Cardiovascular Disease (1985) (2)
Parasite immunity and the major histocompatibility complex (2005) (2)
Transendothelial migration of neutrophils involves integrin-associated protein ( CD 47 ) ( inflammation / extravasation / chemokines / 182 integrins ) (2005) (2)
Lysosomes in immunity to schistosomes and other helminths. (1979) (2)
Newer aspects of regulation of human granulocyte function. (1984) (2)
Establishment of a Human Umbilical Vein Endothelial Cell Line with Normal Functional Capabilities (1994) (1)
Cryptomics : Identification of Novel Bioactive Peptides from Intact Proteins (2007) (1)
Active subnetwork recovery with a mechanism-dependent scoring function; with application to angiogenesis and organogenesis studies (2013) (1)
Letter to the Editor: 1H and 15N chemical shift assignments for domain 4 of the common β-chain of the IL-3, IL-5 and GM-CSF receptors (1999) (1)
Insights into defibrotide as therapy for veno‐occlusive disease (2009) (1)
3.P.236 Regulation of endothelial function by cell-cell junctions (1997) (1)
Sphingosine kinase interacts with TRAF2 and dissects tumor necrosis factor-α signaling. (2011) (1)
Liver-specific deletion of miR-181ab1 reduces liver tumour progression via upregulation of CBX7 (2022) (1)
4.C.4 Anti-atherogenic effects of high density lipoproteins: Mechanisms (1997) (1)
4.P.375 Effect of spherical reconstituted high density lipoprotein apolipoproteins on expression of vascular cell adhesion molecule-1 (1997) (1)
SEPARATION OF HUMAN MONOCYTES AND GUINEA PIG MACROPHAGES BY DENSITY GRADIENTS OF METRIZAMIDE (1981) (1)
Restriction by H-2 gene complex of the transfer of delayed type hypersensitivity in mice. (1976) (1)
cell transcription factor NFAT T- E- selectin expression in endothelial cells by cyclosporin A and the Regulation of granulocyte-macrophage colony-stimulating factor and (2011) (1)
restricted miRNA antagonists of miR-27 - general and VE-cadherin Regulation of vascular leak and recovery from ischemic injury by (2013) (0)
Functional studies onpurified eosinophils andneutrophils from patients withSchistosoma mansoni infections (1980) (0)
Studies on Antigen-Induced Arthritis in Mice (1977) (0)
Regulation of in vitro angiogenesis by anti-integrin antibodies (1992) (0)
Contact residues in the IL-3/IL-3 receptor α-chain complex: Analysis by complementary charge-reversal mutagenesis (1994) (0)
Enhancement and prolongation of t-cell dependent inflammation (delayed type hypersensitivity, dth) by pertussigen in mice. Abstr. (1983) (0)
Enzyme sphingosine kinase (2000) (0)
changes: inhibition by angiopoietin-1 in thrombin-induced endothelial permeability ζ Role of protein kinase C (2013) (0)
Angiogenesis, VasGAP and the actin cytoskeleton (2006) (0)
NMR STRUCTURE OF THE LIGAND BINDING DOMAIN OF THE COMMON BETA-CHAIN IN THE GM-CSF, IL-3 AND IL-5 RECEPTORS (2000) (0)
Human tumournecrosis factor-alpha (TNF-a)directly stimulates arachidonic acidrelease inhumanneutrophils (1990) (0)
Early events in atherogenesis may be inhibited by high density lipoproteins (1995) (0)
breakpoint in the t(15;17) in acute promyelocytic leukemia Localization of the G-CSF gene on chromosome 17 proximal to the (2011) (0)
Structural Basis for the GM-CSF- and IL-3-Mediated Stimulation of Eosinophil Production and Function in Humans (2019) (0)
Anti-Inflammatory Properties of High Density Lipoproteins (2002) (0)
Sphingosine kinase (SphK) mediates transactivation of the epidermal growth factor receptor (EGFR) by estrogen in breast cancer cells (2006) (0)
promyelocytes and myelocytes The clonal proliferation in vitro of enriched populations of human (2011) (0)
Transendothelial Migration Cleaved Annexin A1 in Neutrophil A Proinflammatory Role for Proteolytically (2010) (0)
transcriptional and posttranscriptional level Human interleukin-3 mRNA accumulation is controlled at both the (2011) (0)
1H and 15N chemical shift assignments for domain 4 of the common beta-chain of the IL-3, IL-5 and GM-CSF receptors. (1999) (0)
4.P.374 Inhibition of endothelial cell adhesion molecule expression by high density lipoprotein subfractions (1997) (0)
Fcreceptors on mouse neutrophils andeosinophils: antigenic characteristics, isotype specificity andrelative cell membrane density measured byflow cytometry (1984) (0)
Activities Enhancers That Have Distinct Tissue-Specific Cooperatively by Two NFAT-Dependent The Human IL-3 Locus Is Regulated (2002) (0)
A NOVEL RHOGAP PROTEIN, P74, THAT IS INVOLVED IN ANGIOGENESIS AND CAPILLARY TUBE FORMATION (2004) (0)
Genetic and T-lymphocyte influences on eosinophilia (1984) (0)
Major histocompatibility complex products restrict the adherence of cytolytic T lymphocytes to minor histocompatibility antigens or to trinitrophenyl determinants on schistosomula of Schistosoma mansoni ( H-2 restriction / antigen binding (0)
Identification of circulating sphingosine kinase-related metabolites for prediction of type 2 diabetes (2021) (0)
Leucocyte and endothelial cell biology : the molecular basis of inflammation / by Mathew Alexander Vadas. (2001) (0)
Activating mutations in the common signalling subunit for the GM-CSF, IL-3 and IL-5 receptors: A model of receptor assembly and activation. (1999) (0)
diagnostic and therapeutic molecules (2010) (0)
Regulation de l'expression du gene gm-csf (1988) (0)
cell differentiation marker An autoantibody reactive with nuclei of polymorphonuclear neutrophils: a (2011) (0)
Regulation of Eosinophil Function by P-Selectin (2019) (0)
Sphingosine kinase and their uses (2001) (0)
Okadaic acid: Effects on angiogenesis in vitro (1994) (0)
leads to ligand independence and tumorigenicity granulocyte-macrophage colony-stimulating factor, and IL-5 that A mutation of the common receptor subunit for interleukin-3 (IL-3), (2011) (0)
YAP and the RhoC regulator ARHGAP18, are required to mediate flow-dependent endothelial cell alignment (2020) (0)
Surface expression of host major histocompatibility complex products by schistosomula of schistosoma mansoni. Abstr. (1978) (0)
T-Cell-Mediated Immunopathology in Antigen-Induced Arthritis in Mice (1981) (0)
Inhibition of endothelial cell adhesion molecule expression by reconstituted high-density lipoproteins: Determinants and characteristics (2000) (0)
TITLE: Combined SIM, GSD and TIRF super-resolution approach to localise the RhoGAP protein SENEX in endothelial cells (2014) (0)
Perspectives in Endothelial Cell Research over the Next Decade (1993) (0)
Interferon-y Upregulates Interleukin-3 ( IL-3 ) Receptor Expression in Human Endothelial Cells and Synergizes With IL-3 in Stimulating Major Histocompatibility Complex Class I 1 Expression and Cytokine Production (2002) (0)
Inhibition of in vitro capillary tube formation by activation of B1 integrins (1998) (0)

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