Manjeri A. Venkatachalam
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Manjeri A. Venkatachalam's AcademicInfluence.com Rankings
Manjeri A. Venkatachalamengineering Degrees
Engineering
#5944
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#7232
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Biomedical Engineering
#484
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#494
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Manjeri A. Venkatachalamphilosophy Degrees
Philosophy
#8149
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#11475
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Logic
#5179
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#6557
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Engineering Philosophy
Manjeri A. Venkatachalam's Degrees
- PhD Biomedical Engineering Stanford University
- Doctorate Medicine Stanford University
Why Is Manjeri A. Venkatachalam Influential?
(Suggest an Edit or Addition)Manjeri A. Venkatachalam's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Hyperfiltration in remnant nephrons: a potentially adverse response to renal ablation. (1981) (1836)
- Ischemic damage and repair in the rat proximal tubule: differences among the S1, S2, and S3 segments. (1978) (500)
- Acute kidney injury: a springboard for progression in chronic kidney disease. (2010) (467)
- Failed Tubule Recovery, AKI-CKD Transition, and Kidney Disease Progression. (2015) (451)
- Role of molecular charge in glomerular permeability. Tracer studies with cationized ferritins (1975) (416)
- Altered glomerular permselectivity and progressive sclerosis following extreme ablation of renal mass. (1982) (373)
- Apoptosis: definition, mechanisms, and relevance to disease. (1999) (359)
- Bcl-2 Prevents Bax Oligomerization in the Mitochondrial Outer Membrane* (2001) (322)
- Role of hypoxia-induced Bax translocation and cytochrome c release in reoxygenation injury (1998) (300)
- Mitochondrial dysfunction during hypoxia/reoxygenation and its correction by anaerobic metabolism of citric acid cycle intermediates. (2000) (286)
- Tubular leakage and obstruction after renal ischemia: structural-functional correlations. (1978) (280)
- Calcium in cell injury and death. (2006) (262)
- Mechanisms of cell death in hypoxia/reoxygenation injury (1998) (260)
- Internucleosomal DNA cleavage triggered by plasma membrane damage during necrotic cell death. Involvement of serine but not cysteine proteases. (1997) (248)
- Glomerular filtration of proteins: clearance of anionic, neutral, and cationic horseradish peroxidase in the rat. (1978) (243)
- Association of Bax and Bak Homo-oligomers in Mitochondria (2003) (237)
- Pathogenesis of polycation-induced alterations ("fusion") of glomerular epithelium. (1977) (233)
- Glomerular epithelium: structural alterations induced by polycations. (1975) (223)
- AKI on CKD: heightened injury, suppressed repair, and the underlying mechanisms. (2017) (207)
- Glomerular permeability: in vivo tracer studies with polyanionic and polycationic ferritins. (1977) (179)
- A standard nomenclature for structures of the kidney (1988) (178)
- Mitochondrial Pathology and Glycolytic Shift during Proximal Tubule Atrophy after Ischemic AKI. (2016) (170)
- Alterations in the charge and size selectivity barrier of the glomerular filter in aminonucleoside nephrosis in rats. (1981) (167)
- Tolerance of the human kidney to isolated controlled ischemia. (2013) (163)
- Up-regulation of Apoptosis Inhibitory Protein IAP-2 by Hypoxia (2001) (155)
- The Structural and Molecular Basis of Glomerular Filtration (1978) (142)
- Role of apoptosis in hypoxic/ischemic damage in the kidney. (2003) (136)
- Lipid alterations induced by renal ischemia: pathogenic factor in membrane damage. (1984) (136)
- Contractile properties of cultured glomerular mesangial cells. (1985) (125)
- Mitochondrial quality control in kidney injury and repair (2020) (118)
- Size and charge selective permeability defects induced in glomerular basement membrane by a polycation. (1984) (113)
- Glomerular permeability of macromolecules. Effect of molecular configuration on the fractional clearance of uncharged dextran and neutral horseradish peroxidase in the rat. (1979) (107)
- A Novel Role for MAP1 LC3 in Non-Autophagic Cytoplasmic Vacuolation Death of Cancer Cells (2009) (104)
- AN ULTRASTRUCTURAL STUDY OF GLOMERULAR PERMEABILITY IN AMINONUCLEOSIDE NEPHROSIS USING CATALASE AS A TRACER PROTEIN (1970) (103)
- PTEN loss defines a TGF-β-induced tubule phenotype of failed differentiation and JNK signaling during renal fibrosis. (2012) (100)
- Anaerobic and aerobic pathways for salvage of proximal tubules from hypoxia-induced mitochondrial injury. (2000) (97)
- Energy thresholds that determine membrane integrity and injury in a renal epithelial cell line (LLC-PK1). Relationships to phospholipid degradation and unesterified fatty acid accumulation. (1988) (95)
- Mechanism of proximal tubule brush border loss and regeneration following mild renal ischemia. (1981) (94)
- AN ULTRASTRUCTURAL STUDY OF GLOMERULAR PERMEABILITY USING CATALASE AND PEROXIDASE AS TRACER PROTEINS (1970) (91)
- Role of increased cytosolic free calcium in the pathogenesis of rabbit proximal tubule cell injury and protection by glycine or acidosis. (1991) (89)
- Apoptosis-resistance of hypoxic cells: multiple factors involved and a role for IAP-2. (2003) (88)
- Food restriction retards body growth and prevents end-stage renal pathology in remnant kidneys of rats regardless of protein intake. (1989) (87)
- Structural differences in thin limbs of Henle: physiological implications. (1974) (86)
- Structural requirements for protection by small amino acids against hypoxic injury in kidney proximal tubules 1 (1990) (85)
- Renoprotective approaches and strategies in acute kidney injury. (2016) (83)
- Lysophosphatidic acid increases proximal tubule cell secretion of profibrotic cytokines PDGF-B and CTGF through LPA2- and Gαq-mediated Rho and αvβ6 integrin-dependent activation of TGF-β. (2012) (80)
- Inhibition of autoregulated TGFbeta signaling simultaneously enhances proliferation and differentiation of kidney epithelium and promotes repair following renal ischemia. (2009) (78)
- Serine protease inhibitors suppress cytochrome c-mediatedcaspase-9 activation and apoptosis during hypoxia-reoxygenation. (2000) (76)
- The role of glomerular hyperfiltration in the initiation and progression of diabetic nephropathy. (1981) (75)
- Transforming growth factor-beta (TGF-beta)-inducible gene TMEPAI converts TGF-beta from a tumor suppressor to a tumor promoter in breast cancer. (2010) (75)
- Development of porous defects in plasma membranes of adenosine triphosphate-depleted Madin-Darby canine kidney cells and its inhibition by glycine. (1998) (74)
- Agonist-induced isotonic contraction of cultured mesangial cells after multiple passage. (1985) (73)
- Effects of aminoglycosides on proximal tubule brush border membrane phosphatidylinositol-specific phospholipase C. (1984) (70)
- Heme oxygenase-1 in tissue pathology: the Yin and Yang. (2000) (70)
- Manumycin A inhibits triple-negative breast cancer growth through LC3-mediated cytoplasmic vacuolation death (2013) (66)
- Protection of human umbilical vein endothelial cells by glycine and structurally similar amino acids against calcium and hydrogen peroxide-induced lethal cell injury. (1992) (66)
- Alterations in renal structure and function in a rat model of cyclosporine nephrotoxicity. (1987) (65)
- Extravascular protein in the kidney. An ultrastructural study of its relation to renal peritubular capillary permeability using protein tracers. (1972) (65)
- Severe renal mass reduction impairs recovery and promotes fibrosis after AKI. (2014) (62)
- Gentamicin-induced alterations in pig kidney epithelial (LLC-PK1) cells in culture. (1986) (60)
- GLOMERULAR PERMEABILITY (1969) (59)
- The role of glycine in regulated cell death (2016) (58)
- Differential cytoprotection by glycine against oxidant damage to proximal tubule cells. (1996) (57)
- Alterations in vascular function and morphology in acute ischemic renal failure. (1983) (56)
- TGF-β induced TMEPAI/PMEPA1 inhibits canonical Smad signaling through R-Smad sequestration and promotes non-canonical PI3K/Akt signaling by reducing PTEN in triple negative breast cancer (2014) (55)
- Preservation of complex I function during hypoxia-reoxygenation-induced mitochondrial injury in proximal tubules. (2004) (55)
- Glycine-protected, hypoxic, proximal tubules develop severely compromised energetic function. (1997) (54)
- Potentiation of ischemic renal injury by amino acid infusion. (1983) (54)
- Cytosolic-free calcium increases to greater than 100 micromolar in ATP-depleted proximal tubules. (1997) (50)
- Cytoprotection of kidney epithelial cells by compounds that target amino acid gated chloride channels. (1996) (49)
- Hyperfiltration in remnant nephrons (1981) (47)
- Differential effects of calorie restriction on glomeruli and tubules of the remnant kidney. (1992) (47)
- Myeloma kidney cast nephropathy in a rat model of multiple myeloma. (1983) (46)
- Cyclic AMP-associated shape change in mesangial cells and its reversal by prostaglandin E2. (1984) (44)
- Alanine protects rabbit proximal tubules against anoxic injury in vitro. (1990) (44)
- Conservation of structure in ATP-depleted proximal tubules: role of calcium, polyphosphoinositides, and glycine. (1993) (43)
- PI3K regulation of the SKP-2/p27 axis through mTORC2 (2012) (43)
- Binding of platelet factor four (PF 4) to glomerular polyanion. (1984) (43)
- Contribution of actin cytoskeletal alterations to ATP depletion and calcium-induced proximal tubule cell injury. (1996) (42)
- Regional membrane specialization in the thin limbs of Henle's loops as seen by freeze-fracture electron microscopy. (1979) (42)
- The role of platelets and polycationic mediators in glomerular vascular injury. (1985) (42)
- The Vascular Basis for Acute Renal Failure in the Rat: Preglomerular and Postglomerular Vasoconstriction (1976) (41)
- Structural determinants of glomerular permselectivity. (1977) (41)
- Gene promoter of apoptosis inhibitory protein IAP2: identification of enhancer elements and activation by severe hypoxia. (2002) (41)
- Microangiopathic hemolytic anemia in rats with malignant hypertension. (1968) (41)
- Amino acid protection of cultured kidney tubule cells against calcium ionophore-induced lethal cell injury. (1991) (40)
- Role of myosin light-chain phosphorylation and microtubules in stress fiber morphology in cultured mesangial cells. (1985) (40)
- Vasoactive agents affect mesangial cell adhesion. (1986) (39)
- Tubular hypertrophy due to work load induced by furosemide is associated with increases of IGF-1 and IGFBP-1. (1995) (38)
- Lipid alterations in LLC-PK1 cells exposed to mercuric chloride. (1986) (37)
- Regulation of the mitochondrial permeability transition in kidney proximal tubules and its alteration during hypoxia-reoxygenation. (2009) (35)
- Protection of ATP-depleted cells by impermeant strychnine derivatives: implications for glycine cytoprotection. (2001) (34)
- The tubule pathology of septic acute kidney injury: a neglected area of research comes of age. (2012) (34)
- Energetic determinants of tyrosine phosphorylation of focal adhesion proteins during hypoxia/reoxygenation of kidney proximal tubules. (2001) (33)
- Calcium dependence of integrity of the actin cytoskeleton of proximal tubule cell microvilli. (1996) (33)
- Colocalization of insulin-like growth factor-binding protein with insulin-like growth factor I. (1991) (32)
- Enhancement of glomerular immune complex deposition by a circulating polycation (1984) (32)
- Long‐term response to renal ischaemia in the human kidney after partial nephrectomy: results from a prospective clinical trial (2016) (31)
- Inositol phospholipid metabolism in the kidney. (1986) (31)
- cDNA cloning and promoter analysis of rat caspase-9. (2001) (30)
- Glycine Protection of PC-12 Cells Against Injury by ATP-Depletion (2003) (30)
- Role of intracellular pH during cytoprotection of proximal tubule cells by glycine or acidosis. (1994) (30)
- DESI-MSI and METASPACE indicates lipid abnormalities and altered mitochondrial membrane components in diabetic renal proximal tubules (2020) (28)
- Apoptosis and Cell Death (2009) (27)
- Modulation by Gly, Ca, and acidosis of injury-associated unesterified fatty acid accumulation in proximal tubule cells. (1995) (26)
- Chemical modification of horseradish peroxidase. Preparation and characterization of tracer enzymes with different isoelectric points. (1979) (26)
- Intracellular Ca2+ thresholds that determine survival or death of energy-deprived cells. (1998) (26)
- Characterization of rat kidney proximal tubule brush border membrane-associated phosphatidylinositol phosphodiesterase. (1983) (25)
- Effects of vasopressin on phosphoinositides and prostaglandin production in cultured mesangial cells. (1985) (25)
- A novel wounding device suitable for quantitative biochemical analysis of wound healing and regeneration of cultured epithelium (2010) (24)
- Inhibition of mitochondrial division through covalent modification of Drp1 protein by 15 deoxy-Delta(12,14)-prostaglandin J2. (2010) (24)
- Autophagy inhibition by chloroquine and hydroxychloroquine could adversely affect acute kidney injury and other organ injury in critically ill patients with COVID-19 (2020) (23)
- Increased Smad3 and reduced Smad2 levels mediate the functional switch of TGF-β from growth suppressor to growth and metastasis promoter through TMEPAI/PMEPA1 in triple negative breast cancer (2019) (22)
- Pathology of Acute Renal Failure (1982) (22)
- Effects of Ca++ and glycine on lipid breakdown and death of ATP-depleted MDCK cells. (1995) (22)
- Kidney Complications (1982) (20)
- In vitro perfusion of the isolated dog glomerulus. (1983) (19)
- Critical Blood Pressure Threshold Dependence of Hypertensive Injury and Repair in a Malignant Nephrosclerosis Model (2014) (19)
- New wrinkles in old receptors: core fucosylation is yet another target to inhibit TGF-β signaling. (2013) (19)
- Kidney pericytes: a novel therapeutic target in interstitial fibrosis. (2012) (18)
- Pathophysiology of unilateral ischemia-reperfusion injury: importance of renal counterbalance and implications for the AKI-CKD transition. (2020) (18)
- Proximal Tubular Oxidative Metabolism in Acute Kidney Injury and the Transition to CKD. (2020) (17)
- Glomerular filtration of macromolecules: normal mechanisms and the pathogenesis of proteinuria. (1981) (16)
- Mechanisms of cell injury in ATP-depleted proximal tubules. Role of glycine, calcium, and polyphosphoinositides. (1994) (16)
- Ultrastructure of the local Arthus phenomenon using horseradish peroxidase as antigen. (1970) (16)
- Mitochondrial remodeling following fission inhibition by 15d-PGJ2 involves molecular changes in mitochondrial fusion protein OPA1. (2010) (16)
- Salvage of ischemic cells by impermeant solute and adenosinetriphosphate. (1983) (15)
- Marmoset as a Model to Study Kidney Changes Associated With Aging (2018) (15)
- ULTRASTRUCTURAL STUDIES IN EXPE)t~NTAL NEPHROSIS USING HORSERADISH PEROXIDASE AS A TRACER* (1969) (14)
- Reversible inner medullary vascular obstruction in acute experimental hydronephrosis. (1977) (14)
- Protein restriction or calorie restriction? A critical assessment of the influence of selective calorie restriction on the progression of experimental renal disease. (1989) (13)
- l‐Homoarginine supplementation prevents diabetic kidney damage (2019) (13)
- Tubular cells produce FGF2 via autophagy after acute kidney injury leading to fibroblast activation and renal fibrosis (2022) (12)
- Glomerular localization of platelet cationic proteins after immune complex-induced platelet activation. (1990) (11)
- [A standard nomenclature for structures of the kidney. The Renal Commission of the International Union of Physiological Sciences]. (1994) (10)
- Preserving postischemic reperfusion in the kidney: a role for extracellular adenosine. (2012) (10)
- Elevation of cAMP in cultured mesangial cells diminishes vasopressin-stimulated increases of phosphate uptake and 32P-specific activity in ATP but has no effect on phosphoinositide metabolism. (1987) (9)
- Fibrosis without fibroblast TGF-β receptors? (2015) (9)
- Guanine nucleotides and acute renal failure. (2001) (8)
- The conundrum of protection from AKI by adenosine in rodent clamp ischemia models. (2013) (8)
- Membrane alterations in renal cell injury due to impaired energy metabolism (1985) (8)
- Pericytes Preserve Capillary Integrity to Prevent Kidney Hypoxia. (2017) (7)
- Pathology and pathogenesis of nephrotoxic membrane damage. (1985) (7)
- Proximal tubular epithelial insulin receptor mediates high-fat diet–induced kidney injury (2021) (6)
- Transforming Growth Factor- β (TGF- β ) – Inducible Gene TMEPAI Converts TGF- β from a Tumor Suppressor to a Tumor Promoter in Breast Cancer (2010) (6)
- Distribution of glomerular anionic sites as revealed by polycationic compounds (1976) (5)
- Proximal Tubule LPA1 and LPA2 Receptors use Divergent Signaling Pathways to Additively Increase Profibrotic Cytokine Secretion. (2021) (5)
- Alterations is vascular function and morphology in ischemic ARF (1983) (5)
- Lipid alterations induced by renal ischemia (1984) (4)
- Role of calcium (Ca++) in plasma membrane blebbing and cell death in a kidney epithelial cell line (LLC-PK1) after toxin exposure (1982) (4)
- Could Autophagic Exhaustion Be a Final Common Pathway for Podocytopathy in FSGS? (2015) (4)
- Hepatocyte cytodifferentiation and cell-to-cell communication (2018) (4)
- HEPATIC NECROSIS WITH HAEMORRHAGIC FEVER. (1964) (3)
- Decreased glutathione in ischemic liver and possible protection with thiol administration (1979) (2)
- Glomerular filtration of proteins (1978) (2)
- Relationships between oxidant and non-oxidant mechanisms in the pathogenesis of acute renal failure. (1992) (2)
- Abstract P2-06-08: Interplay of Smad2 and Smad3 during TGF-β induced TMEPAI/ PMEPA1 mediated triple negative breast cancer cell growth (2016) (2)
- Contractile responsiveness of cultured glomerular mesangial (MS) cells in response to vasoactive agents (1985) (2)
- P2-11-04: TMEPAI Is a Feedback Regulator of TGF-b Signaling during Breast Cancer Progression. (2011) (1)
- Apoptosis in Ischemic Disease (2003) (1)
- Morphometric analysis of cortical arterioles in the perfusion fixed rat kidney; an approach to the evaluation of vascular tone (1975) (1)
- Abstract 2280: Role of MAP1LC3 in 15d-PGJ2 induced non-apoptotic and non-autophagic cell death in therapy-resistant triple negative breast tumors (2012) (1)
- Anionization of an antigen promotes glomerular binding and immune complex formation. (1988) (1)
- Abstract P6-12-03: Manumycin A derived nanoparticle induced cytoplasmic vacuolation mediated cell death in triple negative breast cancer (2015) (1)
- Elevations of intracellular cAMP result in a change in cell shape that resembles dome formation in cultured rat glomerular epithelial cells (1986) (1)
- Cyclic nucleotide phosphodiesterase activities in cultured glomerular mesangial cells (1985) (0)
- Abstract 4513: Notch inhibitors relieve growth suppression by TGF-β and promote growth and metastasis of triple-negative breast cancers (2018) (0)
- Table of Contents (2016) (0)
- 4 and Cell Death (2009) (0)
- Pharmacologic and Metabolic Mitochondrial Rescue (2002) (0)
- Inhibition of Drp1 disassembly on mitochondrial remodeling (2009) (0)
- Targeting LC3-SQSTM1 (p62) signaling axis to treat apoptosis resistant and metastatic breast cancers (2010) (0)
- 141 PI3K REGULATES P27 THROUGH MTORC2 IN RENAL CELL CARCINOMA (2012) (0)
- acute renal failure forum Acute renal failure . I . Relative importance of proximal vs . distal tubular injury * (1998) (0)
- GLOMERULAR PERMEABILITY Tracer Studies with Cationized Ferritins (2003) (0)
- Physical Interactions between Macromolecules and the Glomerular Filter (1983) (0)
- Abstract 562: Targeting TMEPAI in breast cancer therapy and prevention (2012) (0)
- Succinate dimethyl ester protects against proximal tubule mitochondrial dysfunction during hypoxia/reoxygenation (1999) (0)
- Abstract 1958: Opposing roles of Smad2 and Smad3 in the regulation of growth and invasion of TNBC through TMEPAI (2017) (0)
- Abstract P4-06-03: TMEPAI a Novel Prognostic Marker for TGF-β Dependency of Metastatic Breast Cancers: Converts Tumor Suppressive TGF-β into a Tumor Promoter (2010) (0)
- Role of myosin light chain (MLC) phosphorylation and microtubules in the assembly and dissolution of stress fibers in a cultured cell type (1984) (0)
- Ethacrynic acid induced mitochondrial fusion is mediated by Inhibition of fission protein Drp1 (2011) (0)
- Hyperfiltration in remnant nephrons: a potentially adverse response to renal ablation. (2001) (0)
- Abstract 5179: TMEPAI, a negative regulator of Smad signaling switches tumor suppressive TGF- β to a tumor promoter in breast tumorigenesis (2011) (0)
- Abstract 3024: Targeting TMEPAI/PMEPA1 inhibits triple negative breast cancer cell growth and metastasis by enhancing growth suppressive TGF-β signaling (2016) (0)
- A standard nomenclature for structures of the kidney (2004) (0)
- Apoptosis of rat kidney proximal tubule cells during hypoxia-reoxygenation A role for cytochrome C (1997) (0)
- Acute Experimental Hydronephrosis (2007) (0)
- Abstract P4-15-06: TMEPAI, a novel drug target in breast cancer therapy and prevention (2013) (0)
- Contralateral nephrectomy‐induced improvement in renal structure and function following unilateral ischemia‐reperfusion injury is counter intuitively associated with markers of renal hypoxia (890.5) (2014) (0)
- Abstract P3-14-09: Targeting TMEPAI/ PMEPA1 inhibited triple negative breast cancer cell growth and metastasis through growth suppressive TGF-β signaling (2016) (0)
- Hemodynamic and histologic studies in the maintenance phase of norepinephrine induced acute renal failure (ARF) (1979) (0)
- Mitochondrial Fusion Precedes Cell Death Induced by 15-Deoxy Δ12, 14 Prostaglandin J2 (2008) (0)
- proximal tubules hypoxia-reoxygenation-induced mitochondrial injury in Preservation of complex I function during (2016) (0)
- Corrigendum to: Marmoset as a Model to Study Kidney Changes Associated With Aging. (2021) (0)
- Abstract 505: Role of TMEPAI-PTEN-PI3K/Akt axis in TGF-β mediated growth and metastasis of breast cancer cells (2015) (0)
- DESI-MSI and METASPACE indicates lipid abnormalities and altered mitochondrial membrane components in diabetic renal proximal tubules (2020) (0)
- Abstract P3-03-11: Notch inhibition promotes triple negative breast cancer growth (2020) (0)
- Cell-to-substrate adhesion in mesangial (MS) cells is affected by hormones which affect contractile behavior (1985) (0)
- Brown-Norway chromosome 1 mitigates the upregulation of pro-inflammatory pathways in mTAL cells and subsequent age-related CKD in Dahl SS/JrHsdMcwi Rats. (2022) (0)
- Proximal Tubular Oxidative Metabolism in Acute Kidney Injury and the Transition to Chronic Kidney Disease (2020) (0)
- Abstract 1947: Divergent effects of Smad2 and Smad3 on TGF-β mediated breast cancer cell growth and expression of TMEPAI/PMEPA1 (2015) (0)
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What Schools Are Affiliated With Manjeri A. Venkatachalam?
Manjeri A. Venkatachalam is affiliated with the following schools:
