M. Ichel Aguet

Q: What Schools Are Affiliated With M. Ichel Aguet

M. Ichel Aguet is affiliated with the following schools: University of Lausanne, Louisiana State University, École Polytechnique Fédérale de Lausanne, Utrecht University, New York University, University of Zurich

M. Ichel Aguet's AcademicInfluence.com Rankings

M. Ichel Aguet

Biology

#11935

World Rank

#15375

Historical Rank

Immunology

#788

World Rank

#811

Historical Rank

biology Degrees

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Biology

M. Ichel Aguet's Degrees

PhD Immunology University of Zurich
Masters Immunology University of Zurich

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M. Ichel Aguet's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Functional role of type I and type II interferons in antiviral defense. (1994) (2580)
Mice devoid of PrP are resistant to scrapie (1993) (2080)
Inducible gene targeting in mice (1995) (1952)
Targeted Disruption of the Stat1 Gene in Mice Reveals Unexpected Physiologic Specificity in the JAK–STAT Signaling Pathway (1996) (1701)
Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein (1992) (1654)
Immune response in mice that lack the interferon-gamma receptor. (1993) (1612)
Deficient T cell fate specification in mice with an induced inactivation of Notch1. (1999) (1523)
Demonstration of an interferon γ-dependent tumor surveillance system in immunocompetent mice (1998) (1284)
Aggressive behavior and altered amounts of brain serotonin and norepinephrine in mice lacking MAOA. (1995) (1192)
The IFN gamma receptor: a paradigm for cytokine receptor signaling. (1997) (1067)
VEGF is required for growth and survival in neonatal mice. (1999) (930)
Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation (2001) (904)
Demonstration of an interferon gamma-dependent tumor surveillance system in immunocompetent mice. (1998) (783)
Deficient signaling in mice devoid of double‐stranded RNA‐dependent protein kinase. (1995) (696)
A stroma-related gene signature predicts resistance to neoadjuvant chemotherapy in breast cancer (2009) (588)
The transcription factor MTF‐1 is essential for basal and heavy metal‐induced metallothionein gene expression. (1994) (477)
Molecular cloning and expression of the human interferon-γ receptor (1988) (397)
Mice that lack the interferon-gamma receptor have profoundly altered responses to infection with Bacillus Calmette-Guerin and subsequent challenge with lipopolysaccharide (1993) (394)
The Orphan Receptor CRF2-4 Is an Essential Subunit of the Interleukin 10 Receptor (1998) (377)
Early interleukin 12 production by macrophages in response to mycobacterial infection depends on interferon gamma and tumor necrosis factor alpha (1995) (374)
Antiviral defense in mice lacking both alpha/beta and gamma interferon receptors (1995) (367)
Immune Defence in Mice Lacking Type I and/or Type II Interferon Receptors (1995) (329)
Interferon gamma receptor deficient mice are resistant to endotoxic shock (1994) (317)
Mice from a genetically resistant background lacking the interferon gamma receptor are susceptible to infection with Leishmania major but mount a polarized T helper cell 1-type CD4+ T cell response (1995) (289)
Notch1 is required for neuronal and glial differentiation in the cerebellum. (2002) (265)
The role of antibody concentration and avidity in antiviral protection. (1997) (259)
Functional analysis of T lymphocyte subsets in antiviral host defense. (1987) (248)
High-affinity binding of 125I-labelled mouse interferon to a specific cell surface receptor (1980) (246)
Interferon-gamma impacts at multiple points during the progression of autoimmune diabetes. (1997) (225)
Ligand-Induced Autoregulation of IFN-γ Receptor β Chain Expression in T Helper Cell Subsets (1995) (213)
Multiple immune abnormalities in tumor necrosis factor and lymphotoxin-α double-deficient mice (1996) (209)
Mice devoid of interferon regulatory factor 1 (IRF‐1) show normal expression of type I interferon genes. (1994) (206)
Notch1 control of oligodendrocyte differentiation in the spinal cord (2002) (200)
A novel member of the interferon receptor family complements functionality of the murine interferon γ receptor in human cells (1994) (196)
Wnt Ligands Secreted by Subepithelial Mesenchymal Cells Are Essential for the Survival of Intestinal Stem Cells and Gut Homeostasis. (2016) (192)
Theiler's virus infection of 129Sv mice that lack the interferon alpha/beta or interferon gamma receptors (1995) (184)
Notch signaling is required for normal prostatic epithelial cell proliferation and differentiation. (2006) (151)
Ligand-induced assembly and activation of the gamma interferon receptor in intact cells (1996) (150)
Mice lacking the IFN-gamma receptor have impaired ability to resolve a lung eosinophilic inflammatory response associated with a prolonged capacity of T cells to exhibit a Th2 cytokine profile. (1996) (148)
Notch1 Deficiency Dissociates the Intrathymic Development of Dendritic Cells and T Cells (2000) (147)
Multiple roles of mouse Numb in tuning developmental cell fates (2001) (139)
Bcl9/Bcl9l are critical for Wnt-mediated regulation of stem cell traits in colon epithelium and adenocarcinomas. (2010) (128)
Antiviral protection by vesicular stomatitis virus-specific antibodies in alpha/beta interferon receptor-deficient mice (1995) (126)
Role of interferon-gamma in interleukin 12-induced pathology in mice. (1995) (126)
High affinity binding of 125I-Labeled mouse interferon to a specific cell surface receptor. II. Analysis of binding properties. (1981) (121)
Fusion of Erythrocytes by Sendai Virus Studied by Immuno-Freeze-Etching (1973) (117)
125I-labelled human interferons alpha, beta and gamma: comparative receptor-binding data. (1985) (116)
Various human interferon alpha subclasses cross-react with common receptors: their binding affinities correlate with their specific biological activities. (1984) (116)
Probing transcription-specific outputs of β-catenin in vivo. (2011) (112)
Generation of nitric oxide and induction of major histocompatibility complex class II antigen in macrophages from mice lacking the interferon gamma receptor. (1993) (111)
IFN-gamma receptor-deficient mice generate antiviral Th1-characteristic cytokine profiles but altered antibody responses. (1994) (106)
Development of antimalaria immunity in mice lacking IFN-gamma receptor. (1995) (95)
BCL9 is an essential component of canonical Wnt signaling that mediates the differentiation of myogenic progenitors during muscle regeneration. (2009) (95)
The stimulatory effects of interleukin (IL)-12 on hematopoiesis are antagonized by IL-12-induced interferon gamma in vivo (1995) (89)
Interferon enhances the expression of Fc gamma receptors. (1980) (86)
Binding of 125I‐labelled human αinterferon to human lymphoid cells (1981) (84)
Cloning of murine interferon gamma receptor cDNA: expression in human cells mediates high-affinity binding but is not sufficient to confer sensitivity to murine interferon gamma. (1989) (81)
Cancer Metastasis: A Reappraisal of Its Underlying Mechanisms and Their Relevance to Treatment. (2018) (78)
Electrophoretically pure mouse interferon inhibits growth, induces liver and kidney lesions, and kills suckling mice. (1981) (74)
Purification of human gamma interferon receptors by sequential affinity chromatography on immobilized monoclonal antireceptor antibodies and human gamma interferon (1987) (68)
Multiple immune abnormalities in tumor necrosis factor and lymphotoxin-alpha double-deficient mice. (1996) (67)
IFN-gamma receptor-deficient mice are hypersensitive to the anti-CD3-induced cytokine release syndrome and thymocyte apoptosis. Protective role of endogenous nitric oxide. (1995) (66)
The in vivo antiviral activity of interleukin-12 is mediated by gamma interferon (1995) (66)
Role of interferon-gamma in contact hypersensitivity assessed in interferon-gamma receptor-deficient mice. (1995) (65)
Treatment of hairy cell leukemia with recombinant alpha interferon: I. Quantitative study of bone marrow changes during the first months of treatment. (1986) (64)
Specific high-affinity binding of 125I-labeled mouse interferon to interfevon resistant embryonal carcinoma cells in vitro. (1981) (61)
Molecular cloning and expression of the human interferon-gamma receptor. (1988) (61)
Treatment of hairy cell leukemia with recombinant alpha interferon: II. In vivo down-regulation of alpha interferon receptors on tumor cells (1986) (60)
A monoclonal antibody against altered LFA‐1 induces proliferation and lymphokine release of cloned T cells (1986) (55)
Normal Hemopoiesis and Lymphopoiesis in the Combined Absence of Numb and Numblike1 (2007) (55)
CD40 ligand has potent antiviral activity (1995) (54)
Binding and cross-linking of recombinant mouse interferon-gamma to receptors in mouse leukemic L1210 cells; interferon-gamma internalization and receptor down-regulation. (1986) (50)
BCL9/9L-β-catenin Signaling is Associated With Poor Outcome in Colorectal Cancer (2015) (50)
Molecular Cloning and Expression of the Human Interferon-y Receptor (1988) (50)
High-affinity binding of 125I-labeled mouse interferon to a specific cell surface receptor. IV. Mouse gamma interferon and cholera toxin do not compete for the common receptor site of alpha / beta interferon. (1982) (49)
Defining new criteria for selection of cell-based intestinal models using publicly available databases (2012) (47)
Similarity of Idiotypic Determinants of T‐ and B‐Lymphocyte Receptors for Alloantigens (1977) (44)
Theiler's Virus Infection of 129Sv Mice That Lack the Interferon c~/B or Interferon ~ Receptors (1995) (44)
PrP‐deficient Mice Are Resistant to Scrapie a (1994) (44)
Induction of specific immune unresponsiveness using purified mixed leukocyte culture-activated T lymphoblasts as autoimmunogen. I. Demonstration of general validity as to species and histocompatibility barriers (1977) (42)
Functional characterization of a hybrid human-mouse interferon gamma receptor: evidence for species-specific interaction of the extracellular receptor domain with a putative signal transducer. (1992) (41)
SOST expression is restricted to the great arteries during embryonic and neonatal cardiovascular development (2007) (40)
Induction, maintenance, and reinduction of tumoricidal activity in bone marrow-derived mononuclear phagocytes by Corynebacterium parvum. Evidence for the involvement of a T cell- and interferon-gamma-independent pathway of macrophage activation. (1987) (40)
Transient Electromagnetic Field Coupling to Long Shielded Cables (1980) (40)
Generation of nitric oxide and clearance of interferon-gamma after BCG infection are impaired in mice that lack the interferon-gamma receptor. (1995) (38)
Pax6-dependent, but β-catenin-independent, function of Bcl9 proteins in mouse lens development (2014) (37)
Absence of detectable serum interferon in acute and chronic viral hepatitis (1986) (36)
Mice That Lack the Interferon- 7 Receptor Have Profoundly Altered Responses to Infection with Bacillus Calmette-Gu6rin and Subsequent Ch-ilenge with Lipopolysaccharide By Ryutaro Kamijo,* Junming l.e,* Deborah Shapiro,* (1993) (34)
Induction of specific immune unresponsiveness with purified mixed leukocyte culture-activated T lymphoblasts as autoimmunogen. II. An analysis of the effects measured at the cellular and serological levels (1978) (33)
The fusion protein SS18-SSX1 employs core Wnt pathway transcription factors to induce a partial Wnt signature in synovial sarcoma (2016) (33)
Mutations in Bcl9 and Pygo genes cause congenital heart defects by tissue-specific perturbation of Wnt/β-catenin signaling (2018) (33)
High affinity human IFN-gamma-binding capacity is encoded by a single receptor gene located in proximity to c-ros on human chromosome region 6q16 to 6q22. (1988) (32)
Receptor dynamics of closely related ligands: ‘fast’ and ‘slow’ interferons. (1985) (30)
The gene for the ligand binding chain of the human interferon gamma receptor (1997) (29)
The Pygo2-H3K4me2/3 interaction is dispensable for mouse development and Wnt signaling-dependent transcription (2013) (28)
Enhancement of Fcγ receptor expression in interferontreated mice (1981) (27)
Susceptibility to scrapie in mice is dependent on PrPC. (1994) (23)
TBX3 acts as tissue-specific component of the Wnt/β-catenin transcriptional complex (2020) (20)
Expansion of gamma delta+ T cells in BALB/c mice infected with Leishmania major is dependent upon Th2-type CD4+ T cells (1995) (19)
Rapid increase of the human IFN-gamma receptor phosphorylation in response to human IFN-gamma and phorbol myristate acetate. Involvement of different serine/threonine kinases. (1990) (19)
Lack of correlation between serum titres of interferon alpha, beta, natural killer cell activity and clinical susceptibility in mice infected with two isolates of lymphocytic choriomeningitis virus. (1987) (17)
The interferon-gamma receptor: a comparison with other cytokine receptors. (1990) (16)
Differential regulation of the human IFN-gamma receptor expression in Raji and IM9 lymphoblastoid cells versus THP-1 monocytic cells by IFN-gamma and phorbol myristate acetate. (1990) (16)
Molecular characterization of the human interferon-gamma receptor: analysis of polymorphism and glycosylation. (1989) (15)
Role of the PrP gene in transmissible spongiform encephalopathies. (1993) (15)
Early Interleukin 12 Production by Macrophages in Response to Mycobacterial Infection Depends on Interferon 3 r and Tumor Necrosis Factor ol By (2003) (14)
Molecular cloning of interferon receptors: a short review (1991) (14)
Role of PrP in prion diseases. (1993) (14)
Antiviral activity of autocrine interferon-beta requires the presence of a functional interferon type I receptor. (1995) (13)
Binding and internalization of gold-labeled IFN-gamma by human Raji cells. (1989) (13)
MHC antigens in interferon γ (IFNγ) receptor deficient mice: IFNγ-independent up-regulation of MHC class II in renal tubules (1995) (13)
Notch 1 Deficiency Dissociates the Intrathymic Development of Dendritic Cells and T Cells (2000) (12)
Involvement of IFN-gamma in Bacillus Calmette-Guérin-induced but not in tumor-induced sensitization to TNF-induced lethality. (1995) (12)
Dissection of the extracellular human interferon gamma receptor alpha-chain into two immunoglobulin-like domains. Production in an Escherichia coli thioredoxin gene fusion expression system and recognition by neutralizing antibodies. (1995) (12)
The Multi-kinase Inhibitor Debio 0617B Reduces Maintenance and Self-renewal of Primary Human AML CD34+ Stem/Progenitor Cells (2017) (12)
Treatment of hairy cell leukemia with recombinant alpha interferon: II. In vivo down-regulation of alpha interferon receptors on tumor cells. (1986) (12)
Human chromosome 21 is necessary and sufficient to confer human IFN gamma responsiveness to somatic cell hybrids expressing the cloned human IFN gamma receptor gene. (1990) (12)
Antigenic correlations between components of C243 and L cell interferons. (1982) (9)
Debio 0617B Inhibits Growth of STAT3-Driven Solid Tumors through Combined Inhibition of JAK, SRC, and Class III/V Receptor Tyrosine Kinases (2016) (9)
Molecular biology of prion diseases. (1993) (9)
Qualitative differences in effects of recombinant α−, β− and γ-interferons on human peripheral blood leukocytes in vitro (1986) (9)
Prevention of interferon-induced augmentation of cellular antitumor effector mechanisms by phorbol esters. (1982) (9)
Signaling steps involving the cytoplasmic domain of the interferon-gamma receptor alpha-subunit are not species-specific. (1994) (8)
A crystalline synthetic peptide representing the epitope of a monoclonal antibody raised against synthetic interferon-alpha 1 fragment 111-166. (1985) (8)
MHC antigens in interferon gamma (IFN gamma) receptor deficient mice: IFN gamma-dependent up-regulation of MHC class II in renal tubules. (1995) (8)
Interferon receptors. (1983) (8)
The Pygo 2H 3 K 4 me 2 / 3 interaction is dispensable for mouse development and Wnt signaling-dependent transcription (7)
Interferon-g impacts at multiple points during the progression of autoimmune diabetes (nonobese diabetic miceyknock-out miceyautoimmune diseaseycytokine) (1997) (7)
Accelerated collagen-induced arthritis in interferon-gamma receptor-deficient mice (1996) (5)
TBX3 acts as tissue-specific component of the Wnt/β-catenin enhanceosome (2020) (5)
Comparison of the direct and indirect immunoferritin tagging of Sendai virus antigen. (1973) (4)
Erratum: A stroma-related gene signature predicts resistance to neoadjuvant chemotherapy in breast cancer (2009) (4)
Variable region cDNA sequences and characterization of murine anti-human interferon γ receptor monoclonal antibodies that inhibit receptor binding by interferon γ (1995) (4)
Epithelial Wnt secretion drives the progression of inflammation-induced colon carcinoma in murine model (2021) (4)
Procedures for studying binding of interferon to mouse cells. (1986) (3)
/Bcl9l Are Critical for Wnt-Mediated Regulation of Stem R l Traits in Colon Epithelium and Adenocarcinomas (2010) (3)
Cloning of murine interferon y receptor cDNA: Expression in human cells mediates high-affinity binding but is not sufficient to confer sensitivity to murine interferon (2)
Knockouts of Interferons, Interferon Receptors and Interferon Signaling Components (1998) (2)
Functional characterization of a hybrid human-mouse interferon Y receptor : Evidence for species-specific interaction of the extracellular receptor domain with a putative signal transducer ( human chromosome 21 / signal transduction ) (2)
Absence of interferon- receptors on hairy cells from a patient resistant to interferon- therapy (1987) (1)
[Circulating interferon in patients with systemic lupus erythematosus. A prospective study]. (1986) (1)
Variable region cDNA sequences and characterization of murine anti-human interferon gamma receptor monoclonal antibodies that inhibit receptor binding by interferon gamma. (1995) (1)
[Interferon production in acute virus hepatitis]. (1984) (0)
Gene Targeting by Homologous Recombination as a Tool to Study the Biophysical Role of the Interferon-γ Signalling Pathway (1991) (0)
Transgenic nonhuman animals without prion protein (1992) (0)
Structure function analysis of the intracellular domain of the human IFN-gamma receptor beta chain (1995) (0)
Cytokine-Mediated Regulation of Inflammation and Immune Response (2014) (0)
Influence of Pyridoxine Administration on thé Transaminase Activity on Tuberculous Patients Treated with Isoniazid in High Dosage. (1961) (0)
Reviewer list for 1995 (1995) (0)
Author response: TBX3 acts as tissue-specific component of the Wnt/β-catenin transcriptional complex (2020) (0)
EMP response calculation on transmission cables (1980) (0)
Defining new criteria for selection of cell-based intestinal models using publicly available databases (2012) (0)
Deficient signaling inmicedevoid ofdouble- stranded RNA-dependent protein kinase (1995) (0)
Abstract #4647: In vivo validation of HectH9 as a cancer target via gene silencing in established orthotopic xenografts. (2009) (0)
REPORTE CORTO / SHORT REPORT - THE IFN ganma PATHOPHYSIOLOGY. THE ROLE OF SOLUBLE IFNganmaRalpha CHAIN (1995) (0)
The PrP-less Mouse: A Tool for Prion Research (1993) (0)
METHOD FOR CALCULATING THE INFLUENCE OF HIGH VOLTAGE CABLES ON TELECOMMUNICATIONS LINES (1976) (0)
Impulse wave attenuation factors of shielding cages (1979) (0)
in mouse lens development-catenin-independent , function of Bcl 9 proteins β Pax 6-dependent , but Material Supplemental (2014) (0)
Influence of the intake of pyridoxine on transaminase activity in patients treated with isoniazid (1960) (0)
Lack the Interferon-7 Receptor Have Profoundly Altered Responses to Infection with Bacillus Calmette-Gu 6 rin and Subsequent Ch-ilenge with Lipopolysaccharide (2003) (0)
The Genetics Company, Inc. - A newly founded Swiss Biotech Company (2000) (0)
IFN-ηRECEPTOR β-CHAIN AND DERIVATIVES THEREOF (1994) (0)
In situ control of HV cables during commissioning test operation or preventive maintenance using partial discharge reflectometry (1987) (0)
Subject Index, Vol. 35, 1993 (1993) (0)
Cell Traits in Colon Epithelium and Adenocarcinomas Bcl9/Bcl9l Are Critical for Wnt-Mediated Regulation of Stem (2018) (0)
Identification of the Sex Pheromone of the German Cockroach, Blattella germanica (2005) (0)
Table of Contents (1995) (0)
Numblike the Combined Absence of Numb and Normal Hemopoiesis and Lymphopoiesis in MacDonald and (2007) (0)
treatment Quantitative study of bone marrow changes during the first months of Treatment of hairy cell leukemia with recombinant alpha interferon: I. (2011) (0)
Numblikethe Combined Absence of Numb and Normal Hemopoiesis and Lymphopoiesis in (2007) (0)
THE IFN ganma PATHOPHYSIOLOGY. THE ROLE OF SOLUBLE IFNganmaR alpha CHAIN (2004) (0)
Aggressive Behavior andAltered Amountsof Brain Serotonin andNorepinephrine in (2016) (0)
We employed two independent approaches to inactivate the angiogenic protein VEGF in newborn mice: inducible, Cre- loxP- mediated gene targeting, or administration of mFlt(1- 3)-IgG, a soluble VEGF receptor chimeric protein. Partial inhibition of VEGF achieved by inducible gene targeting (1999) (0)
MicroRNAs in Ewing’s Sarcoma Master Thesis of Nils Degrauwe (2012) (0)
vivo down-regulation of alpha interferon receptors on tumor cells Treatment of hairy cell leukemia with recombinant alpha interferon: II. In (2011) (0)

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What Schools Are Affiliated With M. Ichel Aguet?

M. Ichel Aguet is affiliated with the following schools: