Merton R. Bernfield
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Philosophy Biology
Merton R. Bernfield's Degrees
- Doctorate Medicine Harvard University
Why Is Merton R. Bernfield Influential?
(Suggest an Edit or Addition)Merton R. Bernfield's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Functions of cell surface heparan sulfate proteoglycans. (1999) (2678)
- Biology of the syndecans: a family of transmembrane heparan sulfate proteoglycans. (1992) (1004)
- Specificities of heparan sulphate proteoglycans in developmental processes (2000) (722)
- Molecular cloning of syndecan, an integral membrane proteoglycan (1989) (466)
- B lymphocytes express and lose syndecan at specific stages of differentiation. (1989) (426)
- Shedding of Syndecan-1 and -4 Ectodomains Is Regulated by Multiple Signaling Pathways and Mediated by a Timp-3–Sensitive Metalloproteinase (2000) (418)
- Members of the syndecan family of heparan sulfate proteoglycans are expressed in distinct cell-, tissue-, and development-specific patterns. (1994) (407)
- Identification of CRAMP, a Cathelin-related Antimicrobial Peptide Expressed in the Embryonic and Adult Mouse* (1997) (394)
- Syndecan-1 is required for Wnt-1-induced mammary tumorigenesis in mice (2000) (384)
- Regulated Shedding of Syndecan-1 and -4 Ectodomains by Thrombin and Growth Factor Receptor Activation* (1997) (373)
- Syndecans, cell surface heparan sulfate proteoglycans, are induced by a proline-rich antimicrobial peptide from wounds. (1994) (372)
- Cell Surface Heparan Sulfate Proteoglycans: Selective Regulators of Ligand-Receptor Encounters* (2000) (357)
- Physiological degradation converts the soluble syndecan-1 ectodomain from an inhibitor to a potent activator of FGF-2 (1998) (340)
- Cell surface proteoglycan binds mouse mammary epithelial cells to fibronectin and behaves as a receptor for interstitial matrix (1988) (307)
- DEPENDENCE OF SALIVARY EPITHELIAL MORPHOLOGY AND BRANCHING MORPHOGENESIS UPON ACID MUCOPOLYSACCHARIDE-PROTEIN (PROTEOGLYCAN) AT THE EPITHELIAL SURFACE (1972) (301)
- Cell surface proteoglycan associates with the cytoskeleton at the basolateral cell surface of mouse mammary epithelial cells (1986) (298)
- Basal lamina of embryonic salivary epithelia. Production by the epithelium and role in maintaining lobular morphology (1977) (274)
- RNA codewords and protein synthesis, VII. On the general nature of the RNA code. (1965) (269)
- The cell surface proteoglycan from mouse mammary epithelial cells bears chondroitin sulfate and heparan sulfate glycosaminoglycans. (1985) (262)
- Hereditary macrothrombocytopathia, nephritis and deafness. (1972) (242)
- Exploitation of syndecan-1 shedding by Pseudomonas aeruginosa enhances virulence (2001) (241)
- Heparan sulfate proteoglycans from mouse mammary epithelial cells. Cell surface proteoglycan as a receptor for interstitial collagens. (1985) (235)
- Immunocytochemistry of cell surface heparan sulfate proteoglycan in mouse tissues. A light and electron microscopic study. (1987) (225)
- Loss of cell surface syndecan-1 causes epithelia to transform into anchorage-independent mesenchyme-like cells. (1995) (223)
- Defects in keratinocyte activation during wound healing in the syndecan-1-deficient mouse (2002) (223)
- Transgenic Expression of Syndecan-1 Uncovers a Physiological Control of Feeding Behavior by Syndecan-3 (2001) (212)
- Syndecan, a developmentally regulated cell surface proteoglycan that binds extracellular matrix and growth factors. (1990) (208)
- Syndecans, Heparan Sulfate Proteoglycans, Maintain the Proteolytic Balance of Acute Wound Fluids* (1998) (202)
- Basal lamina of embryonic salivary epithelia. Nature of glycosaminoglycan and organization of extracellular materials (1977) (199)
- The turnover of basal lamina glycosaminoglycan correlates with epithelial morphogenesis. (1982) (199)
- Cell surface syndecan-1 on distinct cell types differs in fine structure and ligand binding of its heparan sulfate chains. (1994) (193)
- The differential effect of prenatal care on the incidence of low birth weight among blacks and whites in a prepaid health care plan. (1988) (170)
- ACID MUCOPOLYSACCHARIDE (GLYCOSAMINOGLYCAN) AT THE EPITHELIAL-MESENCHYMAL INTERFACE OF MOUSE EMBRYO SALIVARY GLANDS (1972) (167)
- Heparan sulfate proteoglycans from mouse mammary epithelial cells: localization on the cell surface with a monoclonal antibody (1985) (165)
- Cell surface proteoglycan expression correlates with epithelial-mesenchymal interaction during tooth morphogenesis. (1988) (164)
- Syndecans-1 and -4 are induced during wound repair of neonatal but not fetal skin. (1996) (163)
- Core protein structure and sequence determine the site and presence of heparan sulfate and chondroitin sulfate on syndecan-1. (1994) (151)
- Syndecan-1 Shedding Is Enhanced by LasA, a Secreted Virulence Factor of Pseudomonas aeruginosa* (2000) (151)
- Cell surface proteoglycan of mouse mammary epithelial cells is shed by cleavage of its matrix-binding ectodomain from its membrane-associated domain (1987) (150)
- Selective distributions of proteoglycans and their ligands in pericellular matrix of cultured fibroblasts. Implications for their roles in cell-substratum adhesion. (1993) (149)
- Drosophila syndecan: conservation of a cell-surface heparan sulfate proteoglycan. (1994) (144)
- Collagen reduces glycosaminoglycan degradation by cultured mammary epithelial cells: possible mechanism for basal lamina formation. (1979) (142)
- Heparan sulfate proteoglycans from mouse mammary epithelial cells. A putative membrane proteoglycan associates quantitatively with lipid vesicles. (1983) (141)
- Epithelial-mesenchymal interactions regulate the stage-specific expression of a cell surface proteoglycan, syndecan, in the developing kidney. (1989) (141)
- Cell surface proteoglycan of mammary epithelial cells. Protease releases a heparan sulfate-rich ectodomain from a putative membrane-anchored domain. (1985) (136)
- Role of syndecan-1 in leukocyte-endothelial interactions in the ocular vasculature. (2002) (134)
- Glycosaminoglycans and Epithelial Organ Formation (1973) (134)
- Relationship of transformation, cell density, and growth control to the cellular distribution of newly synthesized glycosaminoglycan (1976) (134)
- The basal lamina of the postnatal mammary epithelium contains glycosaminoglycans in a precise ultrastructural organization. (1980) (132)
- Molecular polymorphism of a cell surface proteoglycan: distinct structures on simple and stratified epithelia. (1988) (131)
- Multifactorial inheritance of neural tube defects: localization of the major gene and recognition of modifiers in ct mutant mice (1994) (124)
- Cellular functions of proteoglycans--an overview. (2001) (124)
- Intra- and extracellular control of epithelial morphogenesis. (1970) (115)
- Expression of syndecan gene is induced early, is transient, and correlates with changes in mesenchymal cell proliferation during tooth organogenesis. (1991) (113)
- Remodelling of the basement membrane: morphogenesis and maturation. (1984) (110)
- Transient expression of a cell surface heparan sulfate proteoglycan (syndecan) during limb development. (1990) (109)
- Inhibition by the Soluble Syndecan-1 Ectodomains Delays Wound Repair in Mice Overexpressing Syndecan-1* (2004) (108)
- Expression of syndecan, a putative low affinity fibroblast growth factor receptor, in the early mouse embryo. (1991) (102)
- Type I collagen reduces the degradation of basal lamina proteoglycan by mammary epithelial cells (1981) (101)
- Transcriptional activation of the syndecan-1 promoter by the Wilms' tumor protein WT1. (1996) (99)
- Heparan sulfate proteoglycans from mouse mammary epithelial cells. Basal extracellular proteoglycan binds specifically to native type I collagen fibrils. (1984) (96)
- Developmental expression of syndecan, an integral membrane proteoglycan, correlates with cell differentiation. (1991) (94)
- Syndecan-1, a cell-surface proteoglycan, changes in size and abundance when keratinocytes stratify. (1992) (93)
- Transient expression of syndecan in mesenchymal cell aggregates of the embryonic kidney. (1992) (92)
- Endothelial heparan sulfate proteoglycan. I. Inhibitory effects on smooth muscle cell proliferation. (1990) (91)
- Reduced expression of syndecan-1 in human hepatocellular carcinoma with high metastatic potential. (1997) (90)
- Developmental expression of the syndecans: possible function and regulation. (1993) (84)
- Molecular basis of morphogenesis (1993) (83)
- Syndecan-4 is expressed by B lineage lymphocytes and can transmit a signal for formation of dendritic processes. (1999) (83)
- Collagen synthesis during epitheliomesenchymal interactions. (1970) (81)
- Impaired Abdominal Wall Development and Deficient Wound Healing in Mice Lacking Aortic Carboxypeptidase-Like Protein (2001) (81)
- Simultaneous loss of expression of syndecan-1 and E-cadherin in the embryonic palate during epithelial-mesenchymal transformation. (1998) (81)
- Quantitative variation in serine transfer ribonucleic acid during estrogen-induced phosphoprotein synthesis in rooster liver. (1969) (80)
- Etiology and pathogenesis of human neural tube defects: insights from mouse models. (1994) (76)
- Structural Characterization of Heparan Sulfate and Chondroitin Sulfate of Syndecan-1 Purified from Normal Murine Mammary Gland Epithelial Cells (2001) (74)
- The basal lamina in epithelial-mesenchymal morphogenetic interactions. (1977) (70)
- RNA CODEWORDS AND PROTEIN SYNTHESIS. THE NUCLEOTIDE SEQUENCES OF MULTIPLE CODEWORDS FOR PHENYLALANINE, SERINE, LEUCINE, AND PROLINE. (1965) (69)
- Molecular embryology of the lung: then, now, and in the future. (1999) (68)
- Endothelial cell surface alkaline phosphatase activity is induced by IL-6 released during wound repair. (1997) (68)
- RNA codewords and protein synthesis, 8. Nucleotide sequences of synonym codons for arginine, valine, cysteine, and alanine. (1965) (66)
- Mouse mammary epithelial cells produce basement membrane and cell surface heparan sulfate proteoglycans containing distinct core proteins (1988) (62)
- A curly-tail modifier locus, mct1, on mouse chromosome 17. (1995) (62)
- Constitutive and accelerated shedding of murine syndecan-1 is mediated by cleavage of its core protein at a specific juxtamembrane site. (2005) (62)
- Possible Regulation of FGF Activity by Syndecan, an Integral Membrane Heparan Sulfate Proteoglycan a (1991) (61)
- A specific hepatic transfer RNA for phosphoserine. (1970) (61)
- Accumulation of basement membrane-associated hyaluronate is reduced in the posterior neuropore region of mutant (curly tail) mouse embryos developing spinal neural tube defects. (1988) (60)
- Reduced expression of syndecan‐1 in human hepatocellular carcinoma with high metastatic potential (1997) (58)
- Heparin inhibits proliferation of fetal vascular smooth muscle cells in the absence of platelet‐derived growth factor (1986) (56)
- Epithelial-mesenchymal interactions in uterus and vagina alter the expression of the cell surface proteoglycan, syndecan. (1991) (55)
- Cytochalasin B: lack of effect on mucopolysaccharide synthesis and selective alterations in precursor uptake. (1972) (53)
- Mesenchyme cells degrade epithelial basal lamina glycosaminoglycan. (1982) (52)
- Organization and promoter activity of the mouse syndecan-1 gene. (1993) (52)
- Syndecan, a cell surface proteoglycan, exhibits a molecular polymorphism during lung development. (1991) (50)
- Syndecan-1 and -4 Synthesized Simultaneously by Mouse Mammary Gland Epithelial Cells Bear Heparan Sulfate Chains That Are Apparently Structurally Indistinguishable* (2003) (48)
- AN INTEGRAL MEMBRANE PROTEOGLYCAN IS CAPABLE OF BINDING COMPONENTS OF THE CYTOSKELETON AND THE EXTRACELLULAR MATRIX1 (1982) (46)
- The emerging roles of cell surface heparan sulfate proteoglycans. (1998) (43)
- Glycosaminoglycans can influence fibroblast growth factor-2 mitogenicity without significant growth factor binding. (1997) (43)
- Basal lamina formation by normal and transformed mouse mammary epithelial cells duplicated in vitro. (1981) (41)
- Transformation-induced alterations in fibroblast adhesion: masking by trypsin treatment. (1975) (41)
- Identification and Characterization of Three Drosophila melanogaster Glucuronyltransferases Responsible for the Synthesis of the Conserved Glycosaminoglycan-Protein Linkage Region of Proteoglycans (2003) (40)
- Unlocking the secrets of syndecans: Transgenic organisms as a potential key (2002) (39)
- Molecular embryology and the study of lung development. (1993) (34)
- Heparan sulfate and chondroitin sulfate proteoglycans inhibit E‐selectin binding to endothelial cells (2001) (34)
- Increased Leukocyte-Endothelial Interactions in Syndecan-1–Deficient Mice Involve Heparan Sulfate–Dependent and –Independent Steps (2005) (33)
- Hormonal modification of epithelial differentiation and expression of cell surface heparan sulfate proteoglycan in the mouse vaginal epithelium. An immunohistochemical and electron microscopic study. (1988) (33)
- Hypoxia and endothelial-smooth muscle cell interactions in the lung. (1994) (31)
- Glycosaminoglycans vary in accumulation along the neuraxis during spinal neurulation in the mouse embryo. (1988) (31)
- Binding of Extracellular Effector Molecules by Cell Surface Proteoglycans (1991) (30)
- Ribonuclease and oligoribonucleotide synthesis. I. Synthetic activity of bovine pancreatic ribonuclease derivatives. (1965) (29)
- RNA CODEWORDS AND PROTEIN SYNTHESIS, VI. ON THE NUCLEOTIDE SEQUENCES OF DEGENERATE CODEWORD SETS FOR ISOLEUCINE, TYROSINE, ASPARAGINE, AND LYSINE. (1965) (29)
- The curly tail mouse model of human neural tube defects demonstrates normal spinal cord differentiation at the level of the meningomyelocele: implications for fetal surgery (2001) (28)
- Ribonuclease and oigoribonucleotide synthesis. II. Synthesis of oligonucleotides of specific sequence. (1966) (28)
- Epimorphin is related to a new class of neuronal and yeast vesicle targeting proteins. (1993) (26)
- Insulin promotes shedding of syndecan ectodomains from 3T3-L1 adipocytes: a proposed mechanism for stabilization of extracellular lipoprotein lipase. (2006) (25)
- Hypoxia Inhibits Proliferation of Fetal Pulmonary Arterial Smooth Muscle Cells in Vitro (1986) (24)
- Adhesive Interactions of Murine and Human Trophoblast Cells (1990) (24)
- Defective basal lamina formation by transformed mammary epithelial cells: A reduced effect of collagen on basal lamina (heparan sulfate‐rich) proteoglycan degradation (1982) (23)
- Transformation-induced alterations in adhesion. Binding of pre-formed cell aggregates to cell layers. (1976) (23)
- Use of preformed cell aggregates and layers to measure tissue-specific differences in intercellular adhesion. (1976) (22)
- Mapping of the syndecan genes in the mouse: linkage with members of the myc gene family. (1994) (22)
- Recombinant peptides as immunogens: a comparison of protocols for antisera production using the pGEX system. (1992) (20)
- The Regulation of Cell Behavior by Cell Adhesion (1980) (20)
- Chapter 1 – Proteoglycans: a special class of glycoproteins (1997) (19)
- Developmental expression of the syndecans: possible function and regulation. (1993) (19)
- The enzymatic conversion of glutaminyl-tRNA to pyrrolidone carboxylate-tRNA. (1968) (18)
- Cell-to-cell contact and extracellular matrix: Editorial overview (1990) (18)
- Acquisition of synchronous beating between embryonic heart cell aggregates and layers. (1978) (18)
- Molecular embryology of the lung: then, now, and in the future. (1999) (18)
- Chromosome mapping of the murine syndecan gene. (1991) (16)
- Morphological and functional correlates of synchronous beating between embryonic heart cell aggregates and layers. (1978) (16)
- Deceleration and acceleration in the rate of posterior neuropore closure during neurulation in the curly tail (ct) mouse embryo (2004) (15)
- The cell surface proteoglycan of mouse mammary epithelial cells. The extracellular domain contains N terminus and a peptide sequence present in a conditioned medium proteoglycan. (1988) (15)
- Expression of a Xenopus counterpart of mammalian syndecan 2 during embryogenesis. (1995) (15)
- Endothelial cell proteoglycans: possible mediators of vascular responses to injury. (1990) (14)
- Proteoglycans and Their Role in Wound Repair (1988) (14)
- Ribonuclease and Oligoribonucleotide Synthesis III. OLIGONUCLEOTIDE SYNTHESIS WITH 5'-SUBSTITUTED URIDINE 2',3'-CYCLIC PHOSPHATES (1967) (13)
- Purification of chicken liver seryl transfer ribonucleic acid by complex formation with elongation factor EF-Tu:GTP. A general micromethod of aminoacyl transfer ribonucleic acid purification. (1973) (12)
- Rate of serine transfer ribonucleic acid synthesis during estrogen-induced phosphoprotein synthesis in chick liver. (1973) (12)
- Subcellular redistribution of seryl-transfer RNA during estrogen-induced phosvitin synthesis and specificity of the estrogen effect. (1975) (12)
- Separation of the proliferating and differentiating cell populations of cultured embryonic pancreatic epithelium. (1967) (11)
- Hyaluronan Disappears Intercellularly and Appears at the Basement Membrane Region during Formation of Embryonic Epithelia (1990) (9)
- Expression of syndecan-1 changes during the differentiation of visceral and parietal endoderm from murine F9 teratocarcinoma cells. (1995) (8)
- Matrix regulation of cell proliferation: implications for growth of the embryo. (1984) (7)
- Developmental Biology: Preventive Medicine for Neonatology (1990) (5)
- MORPHOLOGICAL AND FUNCTIONAL CORRELATES OF SYNCHRONOUS BEATING BETWEEN EMBRYONIC HEART CELL AGGREGATES AND LAYERS (1977) (5)
- Morphogenetic Properties of Human Embryonic Cells: Aggregation of Dissociated Cells and Histogenesis in Cultured Aggregates (1974) (5)
- The distribution of syndecan during murine secondary palate morphogenesis. (1992) (5)
- Seryl transfer RNA changes during estrogen-induced phosvitin synthesis and a unique seryl transfer RNA modification. (1971) (5)
- Expression of the cell surface proteoglycan, syndecanm, is induced by epithelial-mesenchymal interaction in dental mesenchyme (1989) (2)
- TISSUE-SPECIFIC DIFFERENCES AND MEMBRANE SITE MOBILITY IN INTERCELLULAR ADHESION (1975) (2)
- Determination of picomole quantities of eukaryotic amino-acyl-tRNA with bacterial elongation factor Tu: the extent of in vivo acylation of tRNA. (1973) (2)
- Quantification of the closure delay of the neural tube in the curly tail mouse embryo (1989) (1)
- Fine mapping and candidate gene analysis of the CT mouse model of neural tube defects (NTD): an approach to identifying human NTD genes. ♦ 278 (1997) (1)
- Inhibition of mammary epithelial glycosaminoglycan (GAG) degradation by collagen (1977) (1)
- Identification and Characterization of Three Drosophila melanogaster Glucuronyltransferases Responsible for the Synthesis of the Conserved Glycosaminoglycan-Protein Linkage Region of Proteoglycans TWO NOVEL HOMOLOGS (2003) (1)
- Syndecan Biology in Wound Repair (2000) (1)
- Basement membranes and cell movement. Introduction. (1984) (1)
- A revived opportunity for fetal research (1993) (1)
- HEPARIN INHIBITS THE PROLIFERATION OF DIVIDING AORTIC AND PULMONARY ARTERIAL SMOOTH MUSCLE CELLS IN VITRO (1984) (0)
- NIEHS/EPA Workshops. Cellular migration. (1997) (0)
- Formation of Dendritic Processes Lymphocytes and Can Transmit a Signal for Syndecan-4 Is Expressed by B Lineage (1999) (0)
- Epithelial-messenchymal interaction regulate the stage-specific expression of a cell surface proteoglycan, snydecan, in developing kidney (1989) (0)
- Interaction of the cell surface with the extracellular matrix during epithelial morphogenesis (1983) (0)
- SYNDECANS, CELL SURFACE HEPARAN SULFATE PROTEOGLYCANS, ARE PRESENT IN AND CAN MODIFY THE PROTEOLYTIC BALANCE OF TRACHEAL ASPIRATES. † 1996 (1996) (0)
- RNA CODEWORDSAND PROTEINSYNTHESIS,VII. ON THE GENERALNATURE OF THE RNA CODE (1965) (0)
- Regulation of Development: Differentiation and Morphogenesis (2011) (0)
- Matrix Interactions of Cell Surface Proteoglycans (2021) (0)
- Book Review:Extracellular Matrix Biochemistry. Karl A. Piez, A. H. Reddi (1985) (0)
- Regulation of the syndecan family of matrix and growth factor co-receptors. Detection of an inductive activity released during wound repair (1993) (0)
- (proteoglycan/type I collagen/basement membrane/extracellula (2016) (0)
- Lack of Syndecan-1 Promotes Leukocyte - Endothelial Interactions in the Ocular Vasculature (2002) (0)
- The heparan sulfate proteoglycan syndecan-1 is a novel regulator of leukocyte-endothelial cell adhesion and leukocyte transmigration (2004) (0)
- RECOGNITION AND ADHESION OF EMBRYONIC CELLS (1974) (0)
- Dependence of Epithelial Morphogenesis on Extracellular Acid Mucopolysaccharide (MPS) (1970) (0)
- Biological Roles of Heparan Sulfate Proteoglycans (2008) (0)
- EPITHELIAL CELL SURFACE PROTEOGLYCAN: A MATRIX RECEPTOR FOR INTERSTITIAL COLLAGENS AND FIBRONECTIN (1987) (0)
- Progress in birth defects research. (1970) (0)
- Retardant of cell growth of the smooth muscles. (1989) (0)
- Localized expression of homeotic genes and the control of embryogenesis in Drosophila (2008) (0)
- Cytokinin activity of transfer RNA during chick embryogenesis. (1972) (0)
- Basement membranes and cell movement (2013) (0)
- Constitutive- and accelerated shedding of syndecan-1, a co-receptor of FGF-signalling, is mediated by cleavage of its core protein at a specific juxtamembrane site (2006) (0)
- SETS FOR ISOLEUCINE, TYROSINE, ASPARAGINE, AND LYSINE (2016) (0)
- HYPOXIA FAILS TO CAUSE HYPERTROPHY OR HYPERPI.ASIA OF FETAL PULMONARY ARTERY SMOOTH MUSCLE CELLS IN VITRO (1984) (0)
- Ribonuclease and oligoribonucleotide synthesis. 3. Oligonucleotide synthesis with 5'-cyclic phosphates. (1967) (0)
- Cytochalasin B:LackofEffect onMucopolysaccharlde Synthesis and Selective Alterations inPrecursor Uptake (glucose transport/DNA, RNA,andprotein synthesis/morphogenesis/microfilaments/plasma membrane) (1972) (0)
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