Michael C. Berndt
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(Suggest an Edit or Addition)Michael C. Berndt's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- PECAM-1 (CD31) cloning and relation to adhesion molecules of the immunoglobulin gene superfamily. (1990) (981)
- Platelet Glycoprotein Ibα Is a Counterreceptor for the Leukocyte Integrin Mac-1 (Cd11b/Cd18) (2000) (577)
- Platelet physiology and thrombosis. (2004) (424)
- The Glycoprotein Ib-IX-V Complex Is a Platelet Counterreceptor for P-Selectin (1999) (359)
- The Vascular Biology of the Glycoprotein Ib-IX-V Complex (2001) (293)
- Characterization of GMP-140 (P-selectin) as a circulating plasma protein (1992) (280)
- Cancer-Associated Thrombosis: An Overview of Mechanisms, Risk Factors, and Treatment (2018) (271)
- Heparin‐induced thrombocytopenia: mechanism of interaction of the heparin‐dependent antibody with platelets (1989) (252)
- Prevention of activated neutrophil adhesion to endothelium by soluble adhesion protein GMP140. (1990) (251)
- Controlled shedding of platelet glycoprotein (GP)VI and GPIb–IX–V by ADAM family metalloproteinases (2007) (241)
- Molecular mechanisms of platelet adhesion and activation. (1997) (230)
- P-selectin anchors newly released ultralarge von Willebrand factor multimers to the endothelial cell surface. (2004) (226)
- Glycoprotein Ib-IX-V. (2003) (216)
- Regulation of in vitro capillary tube formation by anti-integrin antibodies (1993) (207)
- PETA-3/CD151, a member of the transmembrane 4 superfamily, is localised to the plasma membrane and endocytic system of endothelial cells, associates with multiple integrins and modulates cell function. (1999) (195)
- Glycoprotein Ib and glycoprotein IX are fully complexed in the intact platelet membrane. (1987) (194)
- Evidence for activation of tissue factor by an allosteric disulfide bond. (2006) (192)
- Mocarhagin, a novel cobra venom metalloproteinase, cleaves the platelet von Willebrand factor receptor glycoprotein Ibalpha. Identification of the sulfated tyrosine/anionic sequence Tyr-276-Glu-282 of glycoprotein Ibalpha as a binding site for von Willebrand factor and alpha-thrombin. (1996) (189)
- Mechanism of Activation of the GM‐CSF, IL‐3, and IL‐5 Family of Receptors (1998) (188)
- GMP-140 binding to neutrophils is inhibited by sulfated glycans. (1991) (186)
- Sphingosine kinase-1 enhances endothelial cell survival through a PECAM-1-dependent activation of PI-3K/Akt and regulation of Bcl-2 family members. (2005) (182)
- P-selectin Glycoprotein Ligand-1 Is the Major Counter-receptor for P-selectin on Stimulated T Cells and Is Widely Distributed in Non-functional Form on Many Lymphocytic Cells * (1995) (180)
- The Dimeric Versus Monomeric Status of 14-3-3ζ Is Controlled by Phosphorylation of Ser58 at the Dimer Interface* (2003) (178)
- Regulation of platelet membrane levels of glycoprotein VI by a platelet-derived metalloproteinase. (2004) (170)
- The SH2-containing inositol polyphosphate 5-phosphatase, SHIP-2, binds filamin and regulates submembraneous actin (2001) (169)
- Purification of botrocetin from Bothrops jararaca venom. Analysis of the botrocetin-mediated interaction between von Willebrand factor and the human platelet membrane glycoprotein Ib-IX complex. (1989) (168)
- Association of Fyn and Lyn with the Proline-rich Domain of Glycoprotein VI Regulates Intracellular Signaling* (2002) (165)
- Signals from platelet/endothelial cell adhesion molecule enhance the adhesive activity of the very late antigen-4 integrin of human CD34+ hemopoietic progenitor cells. (1994) (162)
- Plasma P-selectin is increased in thrombotic consumptive platelet disorders (1994) (160)
- Anti-beta2-glycoprotein I antibodies in complex with beta2-glycoprotein I can activate platelets in a dysregulated manner via glycoprotein Ib-IX-V. (2006) (159)
- Identification of a membrane skeleton in platelets (1988) (159)
- Ristocetin-dependent reconstitution of binding of von Willebrand factor to purified human platelet membrane glycoprotein Ib-IX complex. (1988) (155)
- A murine antiglycoprotein Ib complex monoclonal antibody, SZ 2, inhibits platelet aggregation induced by both ristocetin and collagen. (1987) (153)
- Ristocetin-dependent, but not botrocetin-dependent, binding of von Willebrand factor to the platelet glycoprotein Ib-IX-V complex correlates with shear-dependent interactions. (2001) (147)
- Platelet Adhesion and Degranulation Induce Pro-Survival and Pro-Angiogenic Signalling in Ovarian Cancer Cells (2011) (147)
- Binding of purified 14-3-3 zeta signaling protein to discrete amino acid sequences within the cytoplasmic domain of the platelet membrane glycoprotein Ib-IX-V complex. (1998) (146)
- Analysis of the Roles of 14-3-3 in the Platelet Glycoprotein Ib-IX–Mediated Activation of Integrin αIIbβ3 Using a Reconstituted Mammalian Cell Expression Model (1999) (141)
- Bernard-Soulier syndrome (1998) (141)
- Requirement of leucine-rich repeats of glycoprotein (GP) Ibalpha for shear-dependent and static binding of von Willebrand factor to the platelet membrane GP Ib-IX-V complex. (2000) (140)
- The Glycoprotein Ib-IX-V Complex in Platelet Adhesion and Signaling (1999) (138)
- Activation-dependent changes in human platelet PECAM-1: phosphorylation, cytoskeletal association, and surface membrane redistribution (1992) (135)
- P-selectin mediates the interaction of circulating leukocytes with platelets and microvascular endothelium in response to oxidized lipoprotein in vivo. (1994) (135)
- Role of Fc receptor gamma-chain in platelet glycoprotein Ib-mediated signaling. (2001) (134)
- Transforming Growth Factor β Suppresses Human Telomerase Reverse Transcriptase (hTERT) by Smad3 Interactions with c-Myc and the hTERT Gene* (2006) (132)
- Bruton tyrosine kinase is essential for botrocetin/VWF-induced signaling and GPIb-dependent thrombus formation in vivo. (2006) (131)
- Platelet GPIb‐IX‐V‐dependent signaling (2005) (128)
- A spontaneous mutation of integrin alpha IIb beta 3 (platelet glycoprotein IIb-IIIa) helps define a ligand binding site. (1992) (125)
- Membrane-associated forms of the beta A4 amyloid protein precursor of Alzheimer's disease in human platelet and brain: surface expression on the activated human platelet. (1994) (125)
- PSGL-1-mediated adhesion of human hematopoietic progenitors to P-selectin results in suppression of hematopoiesis. (1999) (123)
- Purification and preliminary physicochemical characterization of human platelet membrane glycoprotein V. (1981) (122)
- Molecular cloning of cDNA encoding a novel platelet-endothelial cell tetra-span antigen, PETA-3. (1995) (117)
- Cross-linking of a monomeric 39/34-kDa dispase fragment of von Willebrand factor (Leu-480/Val-481-Gly-718) to the N-terminal region of the alpha-chain of membrane glycoprotein Ib on intact platelets with bis(sulfosuccinimidyl) suberate. (1989) (116)
- Association of a phospholipase A2 (14-3-3 protein) with the platelet glycoprotein Ib-IX complex. (1994) (116)
- Identification of aspartic acid 514 through glutamic acid 542 as a glycoprotein Ib-IX complex receptor recognition sequence in von Willebrand factor. Mechanism of modulation of von Willebrand factor by ristocetin and botrocetin. (1992) (113)
- The functional role of platelets in the regulation of angiogenesis (2015) (111)
- Structure of the glycoprotein Ib.IX complex from platelet membranes. (1988) (111)
- Plasma P-selectin is increased in thrombotic consumptive platelet disorders. (1994) (111)
- Corrigendum: 14-3-3ζ regulates the mitochondrial respiratory reserve linked to platelet phosphatidylserine exposure and procoagulant function (2017) (110)
- Phosphoinositide 3-kinase forms a complex with platelet membrane glycoprotein Ib-IX-V complex and 14-3-3ζ (2000) (110)
- Glycoprotein VI is associated with GPIb-IX-V on the membrane of resting and activated platelets (2004) (109)
- Adhesion protein GMP140 inhibits superoxide anion release by human neutrophils. (1991) (105)
- Src family tyrosine kinase Lyn mediates VWF/GPIb-IX-induced platelet activation via the cGMP signaling pathway. (2008) (104)
- A critical role for 14-3-3zeta protein in regulating the VWF binding function of platelet glycoprotein Ib-IX and its therapeutic implications. (2005) (104)
- A role for P selectin in complement-independent neutrophil-mediated glomerular injury. (1994) (104)
- Interaction of calmodulin with the cytoplasmic domain of the platelet membrane glycoprotein Ib-IX-V complex. (2001) (103)
- A Novel Cobra Venom Metalloproteinase, Mocarhagin, Cleaves a 10-Amino Acid Peptide from the Mature N Terminus of P-selectin Glycoprotein Ligand Receptor, PSGL-1, and Abolishes P-selectin Binding (*) (1995) (101)
- Expression and function of members of the cytokine receptor superfamily on breast cancer cells (1997) (100)
- P-selectin and platelet-activating factor mediate initial endotoxin- induced neutropenia (1994) (100)
- Platelet receptor proteolysis: a mechanism for downregulating platelet reactivity. (2007) (99)
- High shear-dependent loss of membrane integrity and defective platelet adhesion following disruption of the GPIbα-filamin interaction. (2011) (94)
- Differential redistribution of platelet glycoproteins Ib and IIb-IIIa after plasmin stimulation. (1991) (94)
- Pathologic shear triggers shedding of vascular receptors: a novel mechanism for down-regulation of platelet glycoprotein VI in stenosed coronary vessels. (2012) (93)
- Primitive human hematopoietic progenitors adhere to P-selectin (CD62P). (1995) (93)
- Molecular interactions between telomerase and the tumor suppressor protein p53 in vitro (1999) (92)
- The role of Nox1 and Nox2 in GPVI-dependent platelet activation and thrombus formation (2014) (88)
- Constitutive Dimerization of Glycoprotein VI (GPVI) in Resting Platelets Is Essential for Binding to Collagen and Activation in Flowing Blood* (2012) (85)
- Binding of a novel 50-kilodalton alboaggregin from Trimeresurus albolabris and related viper venom proteins to the platelet membrane glycoprotein Ib-IX-V complex. Effect on platelet aggregation and glycoprotein Ib-mediated platelet activation. (1996) (85)
- Interaction of calmodulin with the cytoplasmic domain of platelet glycoprotein VI. (2002) (85)
- Dual ITAM-mediated proteolytic pathways for irreversible inactivation of platelet receptors: de-ITAM-izing FcgammaRIIa. (2008) (84)
- Jararhagin and Jaracetin: Novel Snake Venom Inhibitors of the Integrin Collagen Receptor, α2β1 (1995) (84)
- Mice Lacking the ITIM-Containing Receptor G6b-B Exhibit Macrothrombocytopenia and Aberrant Platelet Function (2012) (84)
- Characterization of a novel membrane glycoprotein involved in platelet activation. (1989) (83)
- Chronic expression of P-selectin on endothelial cells stimulated by the T-cell cytokine, interleukin-3. (1996) (83)
- Human interleukin-3 (IL-3) induces disulfide-linked IL-3 receptor alpha- and beta-chain heterodimerization, which is required for receptor activation but not high-affinity binding (1996) (83)
- Regulation of Glycoprotein Ib-IX-von Willebrand Factor Interaction by cAMP-dependent Protein Kinase-mediated Phosphorylation at Ser 166 of Glycoprotein Ibβ* (2002) (82)
- Snake venom modulators of platelet adhesion receptors and their ligands. (2000) (82)
- Epitope mapping of inhibitory antibodies against platelet glycoprotein Ibalpha reveals interaction between the leucine-rich repeat N-terminal and C-terminal flanking domains of glycoprotein Ibalpha. (2001) (81)
- Cyclic AMP-dependent phosphorylation of glycoprotein Ib inhibits collagen-induced polymerization of actin in platelets. (1989) (80)
- The cryptome: a subset of the proteome, comprising cryptic peptides with distinct bioactivities. (2006) (80)
- Identification of a novel integrin beta subunit expressed on cultured monocytes (macrophages). Evidence that one alpha subunit can associate with multiple beta subunits. (1990) (79)
- Coagulation-induced shedding of platelet glycoprotein VI mediated by factor Xa. (2011) (79)
- Characterization of the binding domains on platelet glycoproteins Ib-IX and IIb/IIIa complexes for the quinine/quinidine-dependent antibodies. (1991) (78)
- Bernard–Soulier Syndrome: An Update (2013) (77)
- Soluble Glycoprotein VI Is Raised in the Plasma of Patients With Acute Ischemic Stroke (2011) (77)
- Platelet clearance via shear-induced unfolding of a membrane mechanoreceptor (2016) (77)
- P-selectin interacts with a beta 2-integrin to enhance phagocytosis. (1994) (76)
- Botrocetin/VWF-induced signaling through GPIb-IX-V produces TxA2 in an alphaIIbbeta3- and aggregation-independent manner. (2005) (76)
- Binding of the von Willebrand factor A1 domain to histone. (1997) (76)
- Platelet glycoprotein Ib beta is phosphorylated on serine 166 by cyclic AMP-dependent protein kinase. (1989) (75)
- ITAM receptor‐mediated generation of reactive oxygen species in human platelets occurs via Syk‐dependent and Syk‐independent pathways (2012) (75)
- Primary Platelet Adhesion Receptors (2005) (74)
- Alpha-granule pool of glycoprotein IIb-IIIa in normal and pathologic platelets and megakaryocytes. (1990) (74)
- Primary haemostasis: newer insights (2014) (73)
- Structure and function of the von Willebrand factor A1 domain: analysis with monoclonal antibodies reveals distinct binding sites involved in recognition of the platelet membrane glycoprotein Ib-IX-V complex and ristocetin-dependent activation. (2000) (73)
- Platelet Interactions in Thrombosis (2004) (72)
- Activation-independent, antibody-mediated removal of GPVI from circulating human platelets: development of a novel NOD/SCID mouse model to evaluate the in vivo effectiveness of anti-human platelet agents. (2006) (72)
- Site-specific serine phosphorylation of the IL-3 receptor is required for hemopoietic cell survival. (2000) (70)
- The LFA-1-associated Molecule PTA-1 (CD226) on T Cells Forms a Dynamic Molecular Complex with Protein 4.1G and Human Discs Large* (2004) (70)
- P‐selectin directs T lymphocyte‐mediated injury in delayed‐type hypersensitivity responses: studies in glomerulonephritis and cutaneous delayed‐type hypersensitivity (1996) (70)
- Cytoplasmic domains of GpIbα and GpIbβ regulate 14-3-3ζ binding to GpIb/IX/V (2000) (70)
- The glycoprotein Ib-IX-V complex (2007) (68)
- Measuring soluble platelet glycoprotein VI in human plasma by ELISA (2009) (68)
- Characterization of human platelet GMP-140 as a heparin-binding protein. (1989) (68)
- Regulation of P-selectin binding to the neutrophil P-selectin counter-receptor P-selectin glycoprotein ligand-1 by neutrophil elastase and cathepsin G. (2001) (67)
- Multilineage mobilization of peripheral blood progenitor cells in humans following administration of PEG‐rHuMGDF (1997) (64)
- Ultrastructural demonstration of CD36 in the alpha-granule membrane of human platelets and megakaryocytes. (1993) (63)
- Platelet alpha-granule and plasma membrane share two new components: CD9 and PECAM-1. (1994) (63)
- A Novel Viper Venom Metalloproteinase, Alborhagin, Is an Agonist at the Platelet Collagen Receptor GPVI* (2001) (63)
- TNF receptor‐associated factor 4 (TRAF4) is a novel binding partner of glycoprotein Ib and glycoprotein VI in human platelets (2011) (62)
- Thrombin-induced reactive oxygen species generation in platelets: A novel role for protease-activated receptor 4 and GPIbα (2015) (59)
- Novel Cytokine-independent Induction of Endothelial Adhesion Molecules Regulated by Platelet/Endothelial Cell Adhesion Molecule (CD31) (1997) (56)
- Ligand Binding Rapidly Induces Disulfide-dependent Dimerization of Glycoprotein VI on the Platelet Plasma Membrane* (2007) (55)
- THE THROMBIN RECEPTOR (1994) (55)
- Interaction between von Willebrand factor and glycoprotein Ib activates Src kinase in human platelets: role of phosphoinositide 3-kinase. (2003) (55)
- Compromised ITAM‐based platelet receptor function in a patient with immune thrombocytopenic purpura (2008) (54)
- Purinergic P2Y12 receptor blockade inhibits shear-induced platelet phosphatidylinositol 3-kinase activation. (2003) (54)
- Delineation of the Region in the Glycoprotein VI Tail Required for Association with the Fc Receptor γ-Chain* (2003) (54)
- Current State and Novel Approaches of Antiplatelet Therapy (2015) (53)
- Platelet adhesion: a game of catch and release. (2008) (51)
- Cadherin 6 Has a Functional Role in Platelet Aggregation and Thrombus Formation (2012) (51)
- SHIP-2 forms a tetrameric complex with filamin, actin, and GPIb-IX-V: localization of SHIP-2 to the activated platelet actin cytoskeleton. (2003) (51)
- Identification of a novel 14-3-3ζ binding site within the cytoplasmic tail of platelet glycoprotein Ibα (2004) (51)
- Snake venom probes of platelet adhesion receptors and their ligands. (2005) (51)
- von Willebrand factor mediates platelet spreading through glycoprotein Ib and αIIbβ3 in the presence of botrocetin and ristocetin, respectively (2006) (50)
- Distinct Sulfation Requirements of Selectins Disclosed Using Cells That Support Rolling Mediated by All Three Selectins under Shear Flow (2002) (50)
- Activation of the 43 kDa inositol polyphosphate 5-phosphatase by 14-3-3zeta. (1997) (50)
- Platelet receptor redox regulation (2008) (50)
- Role of calmodulin in platelet receptor function. (2005) (49)
- Targeting Platelets for the Treatment of Cancer (2017) (48)
- Platelet adhesion receptors and (patho)physiological thrombus formation. (2001) (48)
- Characterization of an antiglycoprotein Ib monoclonal antibody that specifically inhibits platelet-thrombin interaction. (1991) (48)
- CD36 forms covalently associated dimers and multimers in platelets and transfected COS-7 cells. (1997) (48)
- Antihemostatic Activity of Human Granzyme B Mediated by Cleavage of von Willebrand Factor* (2008) (48)
- GPIbα-selective activation of platelets induces platelet signaling events comparable to GPVI activation events (2010) (47)
- Programmed autologous cleavage of platelet receptors (2007) (45)
- 14-3-3ζ regulates the mitochondrial respiratory reserve linked to platelet phosphatidylserine exposure and procoagulant function (2016) (44)
- A functional 14-3-3zeta-independent association of PI3-kinase with glycoprotein Ib alpha, the major ligand-binding subunit of the platelet glycoprotein Ib-IX-V complex. (2008) (42)
- Adhesion-dependent signalling and the initiation of haemostasis and thrombosis. (1998) (42)
- Anti-glycoprotein VI monoclonal antibodies directly aggregate platelets independently of FcγRIIa and induce GPVI ectodomain shedding (2009) (39)
- Platelet and vessel wall interaction and the genesis of atherosclerosis. (1986) (39)
- Collagen platelet receptor polymorphisms integrin α2β1 C807T and GPVI Q317L and risk of ischemic stroke (2003) (39)
- The Role of Rac1 in Glycoprotein Ib-IX–Mediated Signal Transduction and Integrin Activation (2012) (38)
- Interaction between von Willebrand factor and glycoprotein Ib activates Src kinase in human platelets: role of phosphoinositide 3-kinase (2003) (38)
- INTERACTION OF THROMBIN WITH PLATELETS: PURIFICATION OF THE THROMBIN SUBSTRATE * (1981) (38)
- Quinine-Dependent Antibodies Bind a Restricted Set of Epitopes on the Glycoprotein Ib-IX Complex: Characterization of the Epitopes (1998) (38)
- Phosphoinositide 3-kinase forms a complex with platelet membrane glycoprotein Ib-IX-V complex and 14-3-3zeta. (2000) (37)
- Leucine-rich Repeats 2-4 (Leu60-Glu128) of Platelet Glycoprotein Ibα Regulate Shear-dependent Cell Adhesion to von Willebrand Factor* (2006) (36)
- Identification of a 14-3-3 Binding Sequence in the Common β Chain of the Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF), Interleukin-3 (IL-3), and IL-5 Receptors That Is Serine-Phosphorylated by GM-CSF (1999) (36)
- An acquired Bernard‐Soulier‐like platelet defect associated with juvenile myelodysplastic syndrome (1988) (36)
- The Cleaved Peptide of PAR1 Results in a Redistribution of the Platelet Surface GPIb-IX-V Complex to the Surface-Connected Canalicular System (2000) (35)
- Specific inhibition of ectodomain shedding of glycoprotein Ibα by targeting its juxtamembrane shedding cleavage site (2013) (35)
- LIM kinase-1 selectively promotes glycoprotein Ib-IX-mediated TXA2 synthesis, platelet activation, and thrombosis. (2013) (34)
- Heparin-induced thrombocytopenia. (1992) (34)
- Binding of von Willebrand factor to the small proteoglycan decorin (2004) (33)
- Angiotensin II–Inducible Platelet-Derived Growth Factor-D Transcription Requires Specific Ser/Thr Residues in the Second Zinc Finger Region of Sp1 (2008) (33)
- MONOCLONAL ANTIBODIES AGAINST ANTIGENS OF THE HUMAN PLATELET SURFACE: PREPARATION AND PROPERTIES (1984) (32)
- The murine monoclonal antibody, 14A2.H1, identifies a novel platelet surface antigen (1991) (32)
- Identification of a 14-3-3 binding sequence in the common beta chain of the granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin-3 (IL-3), and IL-5 receptors that is serine-phosphorylated by GM-CSF. (1999) (32)
- Neutrophil proteinase cathepsin G is proteolytically active on the human platelet glycoprotein Ib-IX receptor: characterization of the cleavage sites within the glycoprotein Ib alpha subunit. (1994) (31)
- Specific Inhibition Of Ectodomain Shedding Of GPIba By Targeting Its Shedding Cleavage Site (2013) (31)
- The Role of Platelet-Derived ADP and ATP in Promoting Pancreatic Cancer Cell Survival and Gemcitabine Resistance (2017) (31)
- Experimental Rupture of Atherosclerotic Lesions Increases Distal Vascular Resistance: A Limiting Factor to the Success of Infarct Angioplasty (2002) (30)
- A Variant of Glanzmann's Thrombasthenia Characterized by Abnormal Glycoprotein IIb/IIIa Complex Formation (1989) (30)
- CD36 Is Spatially Associated with Glycoprotein IIb-IIIa (αIIbβ3) on the Surface of Resting Platelets☆ (1996) (30)
- Identification of a novel 14-3-3zeta binding site within the cytoplasmic tail of platelet glycoprotein Ibalpha. (2004) (30)
- Platelet receptor shedding. (2012) (30)
- von Willebrand factor mediates platelet spreading through glycoprotein Ib and alpha(IIb)beta3 in the presence of botrocetin and ristocetin, respectively. (2006) (29)
- Snake venom metalloproteinases, crotarhagin and alborhagin, induce ectodomain shedding of the platelet collagen receptor, glycoprotein VI (2007) (29)
- Capture by chemical crosslinkers provides evidence that integrin alpha IIb beta 3 forms a complex with protein tyrosine kinases in intact platelets. (1995) (29)
- Characterization of mocarhagin, a cobra venom metalloproteinase from Naja mocambique mocambique, and related proteins from other Elapidae venoms. (1996) (29)
- Functional analysis of the C-terminal flanking sequence of platelet glycoprotein Ib alpha using canine-human chimeras. (2002) (29)
- Factor VIII/von Willebrand factor has potent lectin activity. (1984) (28)
- Functional association of phosphoinositide‐3‐kinase with platelet glycoprotein Ibα, the major ligand‐binding subunit of the glycoprotein Ib–IX–V complex (2010) (27)
- Preliminary functional characterization of a 24,000 dalton platelet surface protein involved in platelet activation. (1985) (26)
- The snake venom toxin alboaggregin-A activates glycoprotein VI. (2001) (26)
- Structure-activity relationships of snake toxins targeting platelet receptors, glycoprotein Ib-IX-V and glycoprotein VI. (2003) (25)
- Detection of an epitope specific for the dissociated form of glycoprotein IIIa of platelet membrane glycoprotein IIb‐IIIa complex and its expression on the surface of adherent platelets (1993) (24)
- The History of Armand Trousseau and Cancer-Associated Thrombosis (2019) (24)
- Role of Focal Adhesion Tyrosine Kinases in GPVI-Dependent Platelet Activation and Reactive Oxygen Species Formation (2014) (23)
- Hypothesis for control of von Willebrand factor multimer size by intra‐molecular thiol‐disulphide exchange (2007) (23)
- Glycoprotein Ib/IX/V binding to the membrane skeleton maintains shear-induced platelet aggregation. (2001) (23)
- The 14-3-3zeta-GPIb-IX-V complex as an antiplatelet target. (2007) (23)
- 4 Bernard-Soulier syndrome (1989) (23)
- Topographical Association of the Platelet Fc-receptor with the Glycoprotein IIb-IIIa Complex. (1993) (22)
- Stimulation of platelet glycoprotein IIb‐IIIa (αIIbβ3‐integrin) functional activity by a monoclonal antibody to the N‐terminal region of glycoprotein IIIa (1996) (22)
- Attenuated platelet sensitivity to collagen in patients with neurofibromatosis type 1 (1995) (22)
- Nerve Growth Factor Inhibits Metalloproteinase-Disintegrins and Blocks Ectodomain Shedding of Platelet Glycoprotein VI* (2010) (22)
- Restored platelet function after romiplostim treatment in a patient with immune thrombocytopenic purpura (2010) (21)
- Microparticles facilitate neutrophil/platelet crosstalk. (2008) (20)
- Transmembrane and Trans-subunit Regulation of Ectodomain Shedding of Platelet Glycoprotein Ibα* (2010) (20)
- Alterations of the levels of glycoproteins Ib-IX and IIb-IIIa in platelets stored at 22°C (1992) (20)
- Fractionation of snake venom metalloproteinases by metal ion affinity: a purified cobra metalloproteinase, Nk, from Naja kaouthia binds Ni2+-agarose. (2007) (20)
- Desialylation of O-glycans on glycoprotein Ibα drives receptor signaling and platelet clearance (2020) (19)
- Jararhagin and jaracetin: novel snake venom inhibitors of the integrin collagen receptor, alpha 2 beta 1. (1995) (19)
- Cisplatin‐induced platelet activation requires mononuclear cells: role of GMP‐140 and modulation of procoagulant activity (1993) (19)
- Pathological shear stress stimulates the tyrosine phosphorylation of alpha-actinin associated with the glycoprotein Ib-IX complex. (2002) (19)
- Characterization of a myeloma patient with a life-threatening hemorrhagic diathesis: presence of a lambda dimer protein inhibiting shear-induced platelet aggregation by binding to the A1 domain of vonWillebrand factor (2005) (19)
- A role for glycosphingolipid‐enriched microdomains in platelet glycoprotein Ib‐mediated platelet activation (2007) (19)
- Activation of von Willebrand factor via mechanical unfolding of its discontinuous autoinhibitory module (2021) (19)
- The GPIb-IX-V Complex (2013) (18)
- Calmodulin interacts with the platelet ADP receptor P2Y1. (2006) (18)
- GMP-140 (P-selectin) inhibits human neutrophil activation by lipopolysaccharide: analysis by proton magnetic resonance spectroscopy. (1992) (17)
- Quinine-dependent antibodies bind a restricted set of epitopes on the glycoprotein Ib-IX complex: characterization of the epitopes. (1998) (17)
- The amino Acid sequence glutamine-628 to valine-646 within the A1 repeat domain mediates binding of von Willebrand factor to bovine brain sulfatides and equine tendon collagen. (1995) (17)
- Identification and characterization of a novel mutation in von Willebrand factor causing type 2B von Willebrand's disease (1999) (16)
- Blood leukocytes bind platelet glycoprotein (IIb-IIIa)' but do not express the vitronectin receptor. (1990) (16)
- Bernard-Soulier syndrome. (1998) (16)
- Platelet glycoprotein Ib a Kozak polymorphism is associated with an increased risk of ischemic stroke (2001) (16)
- Inhibition of chicken liver carboxylesterase by activated carbonyls and carbonyl hydrates. (1996) (15)
- Purification and Preliminary Physicochemical Characterization of Human Platelet Membrane Glycoprotein (2001) (15)
- Thrombospondin in clinical disease states. (1987) (14)
- Heterogeneity of Platelet Fc-receptor-dependent Response to Activating Monoclonal Antibodies. (1992) (14)
- Platelet alpha-granule and plasma membrane share two new components: CD9 and PECAM-1 (1994) (14)
- Determination of the solution structure of a platelet-adhesion peptide of von Willebrand factor. (1992) (14)
- Platelet glycoproteins. (1984) (14)
- The Interaction of von Willebrand Factor and the Platelet Glycoprotein Ib-IX Complex. (1990) (14)
- Platelet Physiology: In Cold Blood (2003) (12)
- The molecular mechanism of platelet adhesion. (1995) (12)
- Molecular Modeling of the Seven Tandem Leucine-Rich Repeats within the Ligand-Binding Region of Platelet Glycoprotein Ibα (2002) (12)
- Snake venom toxins affecting platelet function. (2004) (12)
- A monoclonal antibody to a 67 kD cell membrane glycoprotein directly induces persistent platelet aggregation independently of granule secretion (1991) (12)
- A common epitope on platelet integrin alpha IIb beta 3 (glycoprotein IIbIIIa; CD41b/CD61) and alpha M beta 2 (Mac-1; CDIIb/CD18) detected by a monoclonal antibody. (1996) (11)
- The Interaction of the Factor Vlll/von Willebrand Factor Complex with Hematin (1986) (11)
- Cytoplasmic domains of GpIbalpha and GpIbbeta regulate 14-3-3zeta binding to GpIb/IX/V. (2000) (11)
- Alterations of the levels of glycoproteins Ib-IX and IIb-IIIa in platelets stored at 22 degrees C. (1992) (10)
- Inhibition of Binding of von Willebrand Factor to the Platelet Glycoprotein Ib-IX Complex, Heparin and Sulfatides by Polyanionic Compounds. The Mechanism of Modulation of the Adhesive Function of von Willebrand Factor. (1995) (10)
- An Acquired Defect Associated with Abnormal Signaling of the Platelet Collagen Receptor Glycoprotein VI (2012) (9)
- Botrocetin/VWF-induced signaling through GPIb-IX-V produces TxA2 in an (cid:1) IIb (cid:2) 3- and aggregation-independent manner (2005) (8)
- CD36 is spatially associated with glycoprotein IIb-IIIa (alpha IIb beta 3) on the surface of resting platelets. (1996) (8)
- Serotonin blockade protects against early microvascular constriction following atherosclerotic plaque rupture. (2004) (8)
- The membrane‐proximal intermolecular disulfide bonds in glycoprotein Ib influence receptor binding to von Willebrand factor (2008) (8)
- COMP: an endogenous thrombin inhibitor. (2015) (8)
- An improved method for measuring plasma glycocalicin in the investigation of causes of thrombocytopaenia. (1991) (8)
- Inhibition of chicken liver carboxylesterase (EC 3.1.1.1) by benzils. Direct spectrophotometric evidence for the reversible formation of active-site hemiketal adducts. (1977) (7)
- [Inhibition of Fc-receptor dependent platelet aggregation by monoclonal antibodies against the glycoprotein IIb-IIIa complex]. (1991) (7)
- Stimulation of platelet glycoprotein IIb-IIIa (alpha IIb beta 3-integrin) functional activity by a monoclonal antibody to the N-terminal region of glycoprotein IIIa. (1996) (7)
- Thrombotic thrombocytopenic purpura: reducing the risk? (2011) (7)
- Platelets, Thrombosis and the Vessel Wall (2000) (6)
- A simple, whole blood method for assessment of platelet function: application to dietary intervention. (1998) (6)
- The alpha1 helix-beta13 strand spanning Leu214 to Val229 of platelet glycoprotein Ibalpha facilitates the interaction with von Willebrand factor: evidence from characterization of the epitope of monoclonal antibody AP1. (2004) (6)
- The snake venom toxin alboaggregin-A activates GPVI (2001) (6)
- Tissue factor activation involves disulfide switching (2005) (6)
- Bruton’s tyrosine kinase is essential for botrocetin/vWf-induced signaling and GPIb-dependent thrombus formation in vivo. Running title: GPIb/IX/V-mediated outside-in signaling Hemostasis, Thrombosis, & Vascular Biology (2006) (6)
- Induction of platelet-endothelial interactions in postcapillary venules in hypercholesterolemia: critical role of P-selectin. (2003) (5)
- Ethyl phenylglyoxylate, a simultaneous inhibitor and substrate of chicken liver carboxylesterase (EC 3.1.1.1). Enzyme-catalyzed fragmentation of (E)-benzil monoxime O-2,4-dinitrophenyl ether. (1977) (5)
- A functional 14-3-3 (cid:1) –independent association of PI3-kinase with glycoprotein Ib (cid:2) , the major ligand-binding subunit of the platelet glycoprotein Ib-IX-V complex (2008) (5)
- Platelet a-Granule and Plasma Membrane Share Two New Components : CD 9 and PECAM-l (2000) (4)
- A brief history of blood platelets: A personal view (2017) (4)
- A functional 14-3-3 – independent association of PI 3-kinase with glycoprotein (2008) (4)
- Bernard-soulier Syndrome the Gp Ib-ix-v Complex: Structure and Function (1998) (4)
- Systems biology meets platelet biology. (2008) (4)
- Major Platelet Glycoproteins: GPIB-IX-V (2013) (3)
- Platelets — From Function to Dysfunction in Essential Thrombocythaemia (2011) (3)
- [Conformational changes of the platelet membrane glycoprotein IIb-IIIa complex stimulated by a monoclonal antibody to the N-terminal segment of glycoprotein IIIa]. (1996) (3)
- Distinct Sulfation Requirements of Selectins Disclosed Using Cells Which Support Rolling Mediated by All Three Selectins under Shear Flow: L-SELECTIN PREFERS CARBOHYDRATE 6-SULFATION TO TYROSINE SULFATION WHEREAS P-SELECTIN DOES NOT (2002) (3)
- EPHB2 regulates platelet activation. (2018) (2)
- Dual ITAM-mediated proteolytic pathways for irreversible inactivation of platelet receptors: De-ITAM-ising FcγRIIa Running Title: Platelet receptor regulation (2013) (2)
- Response: Establishing the physiological significance in vivo answers the challenge of unraveling the details of GPIb-initiated signal transduction (2007) (2)
- Ahermatypic corals from the Upper Oligocene of the Rheinberg and Sophia Jacoba 8 weHs (Lower Rhine Embayment) (1995) (2)
- On the origin of platelet factor V (2003) (2)
- Liver-mediated shedding of platelet GPVI. (2016) (2)
- Approaches to the analysis of structure/function of novel membrane receptors: A functional dissection of platelet GP Ib-IX-V (2001) (2)
- Filamin A interaction with GPIbα: the platelet shapes up (2006) (1)
- The 1 helix– 13 strand spanning Leu214 to Val229 of platelet glycoprotein Ib facilitates the interaction with von Willebrand factor: evidence from characterization of the epitope of monoclonal antibody AP1 (2004) (1)
- Full clot retraction: running on mTOR (2007) (1)
- signaling and GPIb-dependent thrombus formation in vivo Bruton tyrosine kinase is essential for botrocetin/VWF-induced (2013) (1)
- Platelet membrane glycoprotein V purification. (1992) (1)
- An event of shear importance. (2011) (1)
- Studies of inherited bleeding disorders to identify platelet membrane glycoproteins involved in adhesion and aggregation. (1982) (1)
- Relation of local platelet glycoprotein IIb/IIIa independent activation during coronary angioplasty in acute myocardial infarction to recovery of left ventricular function. (2003) (1)
- New Direction for WE Thrombin (2007) (1)
- TRANSESTERIFICATION OF TRIS(p-NITROPHENYL) PHOSPHATE WITH SODIUM ALKOXIDES: BIS(p-NITROPHENYL) METHYL PHOSPHATE, BIS(p-NITROPHENYL) BENZYL PHOSPHATE, BIS(p-NITROPHENYL) n-BUTYL PHOSPHATE (1979) (1)
- 14-3-3? regulates the procoagulant function of platelets (2013) (1)
- New catalytic roles for serine esterases: a 19F-NMR study of the interaction of 3,3,3-trifluoro-2,2-dihydroxy-1-phenyl-1-propanone with chicken liver carboxylesterase. (1996) (1)
- Platelet Glycoprotein (GP) Iba Polymorphism and Risk of Stroke (1999) (1)
- Platelet hem-immunoreceptor tyrosine-based activation motif receptors: at least one required. (2013) (1)
- A novel signalling pathway utilized by the GM-CSF/IL-3/IL-5 receptors (1998) (1)
- of platelet glycoprotein Ib-IX and its therapeutic implications protein in regulating the VWF binding function ζ A critical role for 14-3-3 (2013) (0)
- α of platelet glycoprotein Ib binding site within the cytoplasmic tail ζ Identification of a novel 14-3-3 (2013) (0)
- platelet receptors: de-ITAM-izing Fc Dual ITAM-mediated proteolytic pathways for irreversible inactivation of (2013) (0)
- Regulation of P-selectin binding to the neutrophil P-selectin counter-receptor PSGL-1 by neutrophil elastase and cathepsin G (2001) (0)
- Ang II‐Inducible PDGF‐D Transcription Requires Ser/Thr Residues In The Second Zinc Finger Region of Sp1: Novel Phosphospecific Antibodies Demonstrate that Sp1 is Phosphorylated by SMC Injury (2008) (0)
- Bile salt chenodeoxycholate suppresses normal platelet functions through cyclic amp activation pathway (2015) (0)
- Mechanistic studies on chicken liver carboxylesterase (0)
- Thrombin-induced calcium-dependent binding of factor VIII/von willebrand factor to platelets (1984) (0)
- Bacillus thuringiensis applied to spruce budworm, Choristoneura fumiferana (Clemens) (Lepidoptera: Tortricidae), in various dosage ― volume combinations in Michigan U.S.A. (1984) (0)
- The viper venom metalloproteinase-disintegrin, Alborhagin, is an agonist at the platelet collagen receptor GPVI (2001) (0)
- Expression, activation, and function ofintegrin αMβ2 (Mac-1) on neutrophil-derived microparticles. Commentary (2008) (0)
- RAPID LIGAND-INDUCED DIMERIZATION OF PLATELET GLYCOPROTEIN VI (2007) (0)
- Phosphoinositide 3-kinase forms a complex with platelet membrane glycoprotein Ib-IX-V complex and 14-3-3 z (0)
- Mocarhagin, a cobra venom protease, and therapeutic uses thereof (1997) (0)
- membrane glycoprotein Ib-IX-V complex Interaction of calmodulin with the cytoplasmic domain of the platelet (2013) (0)
- Evidence for Control of von Willebrand Factor Multimer Size by Intramolecular Thiol-Disulfide Exchange. (2005) (0)
- Seven Tandem Leucine-Rich Repeats of canine Glycoprotein 1b alpha (2002) (0)
- Alpha actinin binds to glycoprotein (GP) IBA and functions as an adapter for phosphoinositide (PI) 3-kinase in shear stress-activated platelets (2000) (0)
- Recent advances in vascular biology: Selected highlights from IVBM 2008 (2009) (0)
- Abstracts of papers presented at the Japan-UK platelet conference, 2–3 June 2004, Magdalen College, Oxford, UK (2004) (0)
- Arterial thrombosis: going, gone! (2010) (0)
- Acknowledgements to referees (2012) (0)
- Platelet glycoprotein (GP) IB alpha polymorphisms and risk of stroke (1999) (0)
- Platelet GP Ib-IX-V: not just a binding protein (2004) (0)
- FAK, but not Pyk2 is required for GPVI-mediated ROS generation and platelet aggregation. A. (2014) (0)
- A plaque rupture model for ischaemia in the rabbit hindlimb (2000) (0)
- Regulation of Eosinophil Function by P-Selectin (2019) (0)
- Thrombocytopenia and Leukopenia: Demonstration and Characterization of Distinct Antiplatelet and Antileukocyte Antibodies (2016) (0)
- Removing the Covalent Links between GP Ibα and GP Ibβ Hampers Binding of von Willebrand Factor to GP Ib-IX Complex in CHO Cells. (2007) (0)
- Analysis of the Roles of 14-3-3 in the Platelet Glycoprotein Ib-IX–mediated Activation of Integrin (cid:97) IIb (cid:98) 3 Using a Reconstituted Mammalian Cell Expression Model (1999) (0)
- HEMATOPOIESIS Identification of a 14-3-3 Binding Sequence in the Common b Chain of the Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF), Interleukin-3 (IL-3), and IL-5 Receptors That Is Serine-Phosphorylated by GM-CSF (1999) (0)
- Polymorphism of platelet glycoprotein Ib associated with variability of the 85-kDa macroglycopeptide region. (1992) (0)
- 3- and aggregation-independent manner β IIb α an Botrocetin/VWF-induced signaling through GPIb-IX-V produces TxA2 in (2013) (0)
- Characterization o f GMP-140 ( P-selectin ) as a Circula 8 ng Plasma Protein By (2003) (0)
- INHIBITION OF PLATELET FC-RECEPTOR-DEPENDENT AGGREGATION BY A MONOCLONAL ANTIBODY AGAINST THE GLYCOPROTEIN IIB-IIIA COMPLEX (1991) (0)
- CONTROL SHEDDING OF GPIB-IX-V AND GPVI BY ADAM FAMILY METALLOPROTEINASES (2007) (0)
- coronary vessels mechanism for down-regulation of platelet glycoprotein VI in stenosed Pathologic shear triggers shedding of vascular receptors: a novel (2012) (0)
- Contents Vol. 128, 2012 (2012) (0)
- Blood 6 J a N U a R Y 2 0 1 1 I V O L U M E 1 1 7 , N U M B E R 1 (2011) (0)
- The role of NADPH oxidase (NOX) 1 and 2 in GPVI-dependent platelet activation and thrombus formation (2013) (0)
- Approaches to the analysis of structure/function of novel membrane receptors: A functional dissection of platelet GP Ib-IX-V (2006) (0)
- Conformational changes in platelet glycoprotein IIb-IIIa (alpha-IIb-beta-3-integrin) stimulated by a monoclonal antibody to the N-terminal region of glycoprotein IIIa (1996) (0)
- Quinidine-induced thrombocytopenia and leukopenia. In vitro studies of the quinidine-dependent platelet and granulocyte antibodies (1983) (0)
- Inhibition of the Binding of von Willebrand Factor to the Platelet Glycoprotein Ib-IX with an Inhibitor of 14-3-3 and Glycoprotein Ib-IX Interaction. (2005) (0)
- Platelet-VWF complexes get the chop (2008) (0)
- Molecular regulation of platelet adhesion (2008) (0)
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