Michael C. Schotz
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Michael C. Schotzbiology Degrees
Biology
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Molecular Biology
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Biochemistry
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Chemistry Biology
Why Is Michael C. Schotz Influential?
(Suggest an Edit or Addition)Michael C. Schotz's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- A stable, radioactive substrate emulsion for assay of lipoprotein lipase. (1976) (786)
- Lipolytic enzymes and plasma lipoprotein metabolism. (1980) (690)
- Human lipoprotein lipase complementary DNA sequence. (1987) (413)
- The sequence of cDNA encoding lipoprotein lipase. A member of a lipase gene family. (1987) (226)
- The lipase gene family DOI 10.1194/jlr.R200007-JLR200 (2002) (216)
- A rapid assay for lipoprotein lipase. (1970) (206)
- Human genes involved in lipolysis of plasma lipoproteins: mapping of loci for lipoprotein lipase to 8p22 and hepatic lipase to 15q21. (1987) (183)
- Insulin increases the synthetic rate and messenger RNA level of lipoprotein lipase in isolated rat adipocytes. (1988) (173)
- Regulation of lipoprotein lipase. Induction by insulin. (1976) (156)
- A New Insight into Pathogenesis of Carbon Tetrachloride Fat Infiltration.∗ (1960) (154)
- Domain-structure analysis of recombinant rat hormone-sensitive lipase. (1996) (137)
- The fatty liver dystrophy (fld) mutation. A new mutant mouse with a developmental abnormality in triglyceride metabolism and associated tissue-specific defects in lipoprotein lipase and hepatic lipase activities. (1989) (130)
- Synthesis of hepatic lipase in liver and extrahepatic tissues. (1987) (123)
- Effect of triton on lipoprotein lipase of rat plasma. (1957) (122)
- Cloning of rat hepatic lipase cDNA: evidence for a lipase gene family. (1987) (114)
- Lipoprotein lipase and hormone-sensitive lipase activity and mRNA in rat adipose tissue during pregnancy. (1994) (113)
- Isolation and characterization of the human hepatic lipase gene. (1990) (103)
- Genetic and developmental regulation of the lipoprotein lipase gene: loci both distal and proximal to the lipoprotein lipase structural gene control enzyme expression. (1989) (94)
- Chimeras of hepatic lipase and lipoprotein lipase. Domain localization of enzyme-specific properties. (1992) (89)
- ACTH in vitro on Release of Nonesterified Fatty Acids from Adipose Tissues of Adrenalectomized Rats (1959) (86)
- Relationship of lipoprotein lipase activity to triglyceride uptake in adipose tissue. (1967) (84)
- Characterization of triacylglycerol hydrolase activities in isolated myocardial cells from rat heart. (1985) (84)
- A molecular biology-based approach to resolve the subunit orientation of lipoprotein lipase. (1997) (82)
- An enzyme-linked immunoassay for lipoprotein lipase. (1987) (82)
- A role for hepatic lipase in chylomicron and high density lipoprotein phospholipid metabolism. (1984) (82)
- Cloning of an interleukin-4 inducible gene from cytotoxic T lymphocytes and its identification as a lipase (1990) (81)
- Quantitation of amphotericin B with use of high-pressure liquid chromatography. (1977) (81)
- Effect of Norepinephrine and Epinephrine on Nonesterified Fatty Acid Concentration in Plasma (1959) (78)
- Separation of molecular species of lipoprotein lipase from adipose tissue. (1972) (76)
- Expression of hormone-sensitive lipase mRNA in macrophages. (1993) (76)
- Serum gentamicin assay by high-performance liquid chromatography. (1977) (74)
- Maturation of lipoprotein lipase. Expression of full catalytic activity requires glucose trimming but not translocation to the cis-Golgi compartment. (1992) (74)
- A heterozygous mutation (the codon for Ser447----a stop codon) in lipoprotein lipase contributes to a defect in lipid interface recognition in a case with type I hyperlipidemia. (1992) (73)
- Synthesis and regulation of lipoprotein lipase in the hippocampus. (1990) (73)
- Lipoprotein lipase domain function. (1994) (68)
- Effect of Carbon Tetrachloride on Release of Free Fatty Acids by Rat Adipose Tissue.∗ (1960) (67)
- USE OF MULTICOMPARTMENTAL MODELS TO MEASURE RATES OF TRIGLYCERIDE METABOLISM IN RATS. (1964) (67)
- Localization of lipoprotein lipase mRNA in selected rat tissues. (1989) (66)
- Domain exchange: characterization of a chimeric lipase of hepatic lipase and lipoprotein lipase. (1991) (61)
- Intra- and extracellular forms of lipoprotein lipase in adipose tissue. (1976) (61)
- Identification of the active site serine of hormone‐sensitive lipase by site‐directed mutagenesis (1994) (58)
- RFLP for the human lipoprotein lipase (LPL) gene: HindIII. (1987) (58)
- Determination of lipid A and endotoxin in serum by mass spectroscopy. (1978) (57)
- Familial chylomicronemia (type I hyperlipoproteinemia) due to a single missense mutation in the lipoprotein lipase gene. (1991) (56)
- Hepatic lipase: site-directed mutagenesis of a serine residue important for catalytic activity. (1990) (55)
- Lipoprotein lipase: size of the functional unit determined by radiation inactivation. (1983) (55)
- Determination of aminoglycoside antibiotics in biological fluids: a review. (1979) (54)
- Rapid increase of rat-liver triglycerides following carbon tetrachloride poisoning. (1960) (53)
- Cloning and expression of apolipoprotein B, the major protein of low and very low density lipoproteins. (1985) (53)
- Quantitative aspects of free fatty acid metabolism in the fasted rat. (1967) (53)
- Regulation of expression of the lipoprotein lipase gene in brown adipose tissue. (1992) (51)
- Effect of adrenergic blocking agents on the release of free fatty acids from rat adipose tissue. (1960) (49)
- Release of lipoprotein lipase activity from isolated fat cells. II. Effect of heparin. (1974) (49)
- Paradoxical effect on atherosclerosis of hormone-sensitive lipase overexpression in macrophages. (1999) (48)
- Rapid changes in rat heart lipoprotein lipase activity after feeding carbohydrate. (1980) (47)
- Immunocytochemical localization of the functional fraction of lipoprotein lipase in the perfused heart. (1983) (46)
- Hepatic lipase. Purification and characterization. (1984) (45)
- Isolation and characterization of the gene for mouse hormone-sensitive lipase. (1994) (45)
- Hydrolysis of chylomicron arachidonate and linoleate ester bonds by lipoprotein lipase and hepatic lipase. (1987) (44)
- Evidence for hormone-sensitive lipase mRNA expression in human monocyte/macrophages. (1997) (44)
- Postnatal recruitment of brown adipose tissue is induced by the cold stress experienced by the pups. An analysis of mRNA levels for thermogenin and lipoprotein lipase. (1989) (43)
- Nucleotide sequence of rat adipose hormone sensitive lipase cDNA. (1988) (41)
- Hepatic triglyceride secretion in relation to lipogenesis and free fatty acid mobilization in fasted and glucose-refed rats. (1968) (41)
- Studies on release of lipoprotein lipase activity from fat cells. (1971) (40)
- Hepatic lipase: a member of a family of structurally related lipases. (1987) (38)
- Carboxyl ester lipase: a highly polymorphic locus on human chromosome 9qter. (1991) (38)
- Detection and partial characterization of lipoprotein lipase in bovine aorta. (1975) (36)
- Antibodies to lipoprotein lipase. Application to perfused heart. (1977) (36)
- Evidence for independent genetic regulation of heart and adipose lipoprotein lipase activity. (1983) (36)
- Effect of nutrition on species of lipoprotein lipase. (1972) (36)
- Hormone-sensitive lipase overexpression increases cholesteryl ester hydrolysis in macrophage foam cells. (1997) (35)
- Hormone-Sensitive Lipase Overexpression Increases Cholesteryl Ester Hydrolysis in Macrophage Foam Cells (1998) (35)
- Chapter 11 Lipoprotein lipase (1987) (33)
- Rat heart lipoprotein lipase. (1975) (33)
- Quantitation of Antibiotics Using High-Pressure Liquid Chromatography: Tetracycline (1976) (32)
- Homology of lipoprotein lipase to pancreatic lipase. (1986) (32)
- Assignment of human pancreatic lipase gene (PNLIP) to chromosome 10q24-q26. (1991) (32)
- Hormonal mediation of rat heart lipoprotein lipase activity after fat feeding. (1981) (31)
- A simple lipase assay using trichloroacetic acid. (1972) (31)
- EFFECT OF CARBON TETRACHLORIDE INGESTION ON LIVER AND PLASMA TRIGLYCERIDE TURNOVER RATES. (1964) (30)
- ANALYSIS OF GLUCOSE-C14 IN TISSUES USING THIN-LAYER CHROMATOGRAPHY. (1965) (29)
- Amikacin Assay in Serum by High-Performance Liquid Chromatography (1978) (29)
- The fatty liver dystrophy (fld) mutation (1989) (28)
- Quantitation of Antibiotics by High-Pressure Liquid Chromatography: Cephalothin (1978) (27)
- The role of the liver in the uptake of plasma and chyle triglycerides in the rat. (1966) (26)
- Heparin-releasable and nonreleasable lipoprotein lipase in the perfused rat heart. (1981) (26)
- Hydrolysis of tri- and monoacylglycerol by lipoprotein lipase: evidence for a common active site. (1976) (26)
- Domain Identification of Hormone-sensitive Lipase by Circular Dichroism and Fluorescence Spectroscopy, Limited Proteolysis, and Mass Spectrometry* (1999) (25)
- High-pressure liquid chromatography for quantitation of antimicrobial agents. (1980) (24)
- Lipoprotein lipase in cultured heart cells: characteristics and cellular location. (1977) (23)
- The effect of puromycin and actinomycin on carbohydrate-induced lipase activity in rat adipose tissue. (1965) (22)
- Further studies on cholesterol in liver cell fractions of normal and cholesterol fed rats. (1953) (22)
- Hormone-sensitive lipase: structure, function, evolution and overproduction in insect cells using the baculovirus expression system. (1994) (22)
- Rebound phenomenon complicating cerebral dehydration with glycerol. Case report. (1975) (21)
- Reduced atherosclerosis in hormone-sensitive lipase transgenic mice overexpressing cholesterol acceptors. (2003) (21)
- Isolated Fat Cells: Morphology and Possible Role of Released Lipoprotein Lipase in Deposition of Lipoprotein Fatty Acid (1969) (21)
- Sequential induction of two species of lipoprotein lipase. (1973) (20)
- Effect of N-linked glycosylation on hepatic lipase activity. (1991) (19)
- Low level expression of hormone-sensitive lipase in arterial macrophage-derived foam cells: potential explanation for low rates of cholesteryl ester hydrolysis. (2000) (19)
- Effect of low fat and high fat diets on the synthesis of cholesterol in rats. (1952) (18)
- Regulation of lipoprotein lipase immunological study of adipose tissue. (1978) (16)
- Assignment of the human pancreatic colipase gene to chromosome 6p21.1 to pter. (1991) (16)
- Properties of binding of Escherichia coli endotoxin to various matrices (1981) (16)
- Mechanisms of increased lipoprotein lipase in fat cells of obese Zucker rats. (1991) (15)
- Lipoprotein lipase activity in adipose tissue from obese human beings. (1981) (15)
- Large-scale purification and kinetic properties of recombinant hormone-sensitive lipase from baculovirus-insect cell systems. (1997) (15)
- Release of lipoprotein lipase from fat cells. (1969) (14)
- The investigation of a cholesterol esterase in rat liver. (1954) (14)
- Quantitation of serum tobramycin concentration using high-pressure liquid chromatography. (1979) (13)
- Lipoprotein lipase activity of adult rat cardiocytes. (1980) (11)
- The effect of anesthesia on the fate of injected free fatty acid. (1966) (11)
- VNTR polymorphism in the hepatic lipase gene (LIPC). (1991) (11)
- Changes in cholesterol distribution in lever cell fractions of rats fed cholesterol. (1953) (10)
- Purification and characterization of lipoprotein lipase from human heart. (1976) (10)
- Expression of biologically active hormone‐sensitive lipase in mammalian (COS) cells (1991) (10)
- Hepatic lipase: high-level expression and subunit structure determination. (1997) (10)
- Stimulation of release of lipoprotein lipase activity from isolated fat cells by rat serum. (1973) (9)
- Hepatic and plasma lipases. (1992) (8)
- Lipase engineering: a window into structure-function relationships. (1997) (7)
- Mechanism of alteration of the functional fraction of lipoprotein lipase in rat heart. (1980) (7)
- Activation of lipoprotein lipase by blood platelets. (1974) (6)
- PLASMA FREE FATTY ACID TURNOVER IN CARBON TETRACHLORIDE-TREATED RATS. (1965) (6)
- Determination of Amikacin Isomers by High Pressure Liquid Chromatography (1979) (6)
- Two polymorphisms for the human hepatic lipase (HL) gene. (1988) (5)
- Effect of reticuloendothelial blocking agents on plasma and liver cholesterol levels in the rat. (1954) (5)
- Triglyceride Lipases, Hypertriglyceridemia and Atherosclerosis (1992) (5)
- Positional specificity of adipose tissue lipoprotein lipase (1974) (5)
- Effect of glucose and insulin on fatty acid synthetase activity in rat adipocytes. (1971) (4)
- Interaction of serum lipoproteins with heparin and phenol. (1957) (3)
- Specific conditions for enhancement of lipoprotein lipase activity by platelets. (1975) (3)
- Chimeras of Hepatic Lipase and Lipoprotein Lipase (2001) (2)
- Metabolic studies of adipose tissue in acute uremia. (1981) (2)
- Interaction of two fractions of heart lipoprotein lipase with natural and synthetic substrates (1981) (2)
- Twopolymorphisms forthehumanhepatic lipase (HL)gene (1987) (1)
- A stable , radioactive substrate emulsion for assay of I i poprotein I ipase (2003) (1)
- Dinucleotide repeat polymorphisms at the lipoprotein lipase (LPL) locus (1993) (1)
- Effect of carbohydrates on lipoprotein lipase activity releasable from rat heart (1977) (0)
- Effect of serum on phospholipids of L-forms of Streptococcus faecalis (1976) (0)
- Cloning of rat hepatic lipase cDNA gene family (lipoprotein lipase/pancreatic lipase) (2016) (0)
- Incorporation of 1-14C-Palmitate into Liver and Serum Triglycerides of Choline Deficient Rats.∗ (1963) (0)
- , CHOLESTEROL IN RATS DIETS ON THE SYNTHESIS OF EFFECT OF LOW FAT AND HIGH FAT (2003) (0)
- The Molecular Basis of the Chylomicronemia Syndrome (1991) (0)
- 1994 Aspen Bile Acid/Cholesterol/Lipoprotein Conference: fatty acid metabolism in liver and adipose tissue. (1995) (0)
- Genetic Regulation of Lipoprotein Lipase (1983) (0)
- Determinationof AminoglycosideAntibioticsin BiologicalFluids : A Review (2004) (0)
- Lipoprotein lipase in cultured heart cells: Characteristics and cellular location (1977) (0)
- RELPforthehumanlipoprotein lipase (LPL)gene:HindM (1987) (0)
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