Mario Comporti
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Cell Biology
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Chemistry Biology
Mario Comporti's Degrees
- PhD Biochemistry University of Padua
- Masters Chemistry University of Padua
Why Is Mario Comporti Influential?
(Suggest an Edit or Addition)Mario Comporti's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Identification of 4-hydroxynonenal as a cytotoxic product originating from the peroxidation of liver microsomal lipids. (1980) (697)
- Lipid peroxidation and cellular damage in toxic liver injury. (1985) (596)
- Three models of free radical-induced cell injury. (1989) (386)
- Protection against oxidative damage of erythrocyte membrane by the flavonoid quercetin and its relation to iron chelating activity (1997) (362)
- Lipid peroxidation and cellular damage in extrahepatic tissues of bromobenzene-intoxicated mice. (1986) (276)
- Gamma-glutamyl transpeptidase-dependent iron reduction and LDL oxidation--a potential mechanism in atherosclerosis. (1999) (212)
- Iron release, oxidative stress and erythrocyte ageing. (2002) (203)
- Iron release and membrane damage in erythrocytes exposed to oxidizing agents, phenylhydrazine, divicine and isouramil. (1992) (194)
- Glutathione depleting agents and lipid peroxidation. (1987) (178)
- Studies on the mechanism of formation of 4-hydroxynonenal during microsomal lipid peroxidation. (1986) (173)
- Hydrogen peroxide produced during γ‐glutamyl transpeptidase activity is involved in prevention of apoptosis and maintainance of proliferation in U937 cells (1999) (173)
- Liver glutathione depletion induced by bromobenzene, iodobenzene, and diethylmaleate poisoning and its relation to lipid peroxidation and necrosis. (1985) (164)
- Redox modulation of cell surface protein thiols in U937 lymphoma cells: the role of gamma-glutamyl transpeptidase-dependent H2O2 production and S-thiolation. (1999) (161)
- Cytotoxic aldehydes originating from the peroxidation of liver microsomal lipids. Identification of 4,5-dihydroxydecenal. (1984) (144)
- Histochemical detection of lipid peroxidation in the liver of bromobenzene-poisoned mice. (1987) (142)
- Ethanol-induced oxidative stress: basic knowledge (2010) (141)
- Systemic oxidative stress in classic Rett syndrome. (2009) (132)
- Lipid peroxidation and antioxidant systems in the liver injury produced by glutathione depleting agents. (1990) (132)
- Effects of diffusible products of peroxidation of rat liver microsomal lipids. (1979) (131)
- Lipid peroxidation and biogenic aldehydes: from the identification of 4-hydroxynonenal to further achievements in biopathology. (1998) (113)
- Purification of NADPH-dependent dehydroascorbate reductase from rat liver and its identification with 3 alpha-hydroxysteroid dehydrogenase. (1994) (113)
- Polyunsaturated Fatty Acid Pattern in Liver and Erythrocyte Phospholipids from Obese Patients (2007) (111)
- F2-isoprostanes are not just markers of oxidative stress. (2008) (105)
- Effect of CCl-4 in vitro and in vivo on lipid peroxidation of rat liver homogenates and subcellular fractions. (1965) (104)
- Plasma F2-isoprostanes are elevated in newborns and inversely correlated to gestational age. (2004) (104)
- gamma-Glutamyl transpeptidase-dependent lipid peroxidation in isolated hepatocytes and HepG2 hepatoma cells. (1997) (101)
- Effect of in vivo and in vitro ethanol administration on liver lipid peroxidation. (1967) (100)
- Lipid peroxidation. Biopathological significance. (1993) (95)
- Glutathione depletion: its effects on other antioxidant systems and hepatocellular damage. (1991) (90)
- Measurement of lipid peroxidation in vivo: A comparison of different procedures (1987) (84)
- Evidence for aldehydes bound to liver microsomal protein following CCl4 or BrCCl3 poisoning. (1982) (83)
- Loss of lipid peroxidation as a histochemical marker for preneoplastic hepatocellular foci of rats. (1984) (83)
- Free iron, total F2‐isoprostanes and total F4‐neuroprostanes in a model of neonatal hypoxic–ischemic encephalopathy: neuroprotective effect of melatonin (2009) (79)
- Purification and characterization of glutathione-dependent dehydroascorbate reductase from rat liver. (1994) (78)
- Detection of carbonyl functions in phospholipids of liver microsomes in CCl4- and BrCCl3-poisoned rats. (1982) (78)
- Effect of free iron on collagen synthesis, cell proliferation and MMP-2 expression in rat hepatic stellate cells. (2002) (77)
- Extraction and partial characterization of dialysable products originating from the peroxidation of liver microsomal lipids and inhibiting microsomal glucose 6-phosphatase activity. (1979) (77)
- Membrane gamma-glutamyl transpeptidase activity of melanoma cells: effects on cellular H(2)O(2) production, cell surface protein thiol oxidation and NF-kappa B activation status. (2000) (74)
- Iron release, membrane protein oxidation and erythrocyte ageing (1995) (74)
- γ‐Glutamyltransferase‐dependent prooxidant reactions: A factor in multiple processes (2003) (67)
- Inhibition of protein synthesis by carbonyl compounds (4-hydroxyalkenals) originating from the peroxidation of liver microsomal lipids. (1981) (64)
- Formation, reactions and toxicity of aldehydes produced in the course of lipid peroxidation in cellular membranes (1987) (63)
- MgATP-dependent glucose 6-phosphate-stimulated Ca2+ accumulation in liver microsomal fractions. Effects of inositol 1,4,5-trisphosphate and GTP. (1988) (63)
- Cleavage of Bcl-2 in oxidant- and cisplatin-induced apoptosis of human melanoma cells (2001) (59)
- Lipid peroxidation, protein thiols and calcium homeostasis in bromobenzene-induced liver damage. (1987) (59)
- Loss of membrane protein thiols and lipid peroxidation in allyl alcohol hepatotoxicity. (1991) (58)
- Detection of 4-hydroxynonenal and other lipid peroxidation products in the liver of bromobenzene-poisoned mice. (1986) (58)
- Ion trap tandem mass spectrometric determination of F2-isoprostanes. (2003) (57)
- Iron Release in Erythrocytes and Plasma Non Protein-bound Iron in Hypoxic and Non Hypoxic Newborns (2003) (56)
- F2-isoprostanes stimulate collagen synthesis in activated hepatic stellate cells: a link with liver fibrosis? (2005) (53)
- Plasma Esterified F2-Isoprostanes and Oxidative Stress in Newborns: Role of Nonprotein-Bound Iron (2008) (52)
- Release of free, redox-active iron in the liver and DNA oxidative damage following phenylhydrazine intoxication. (1997) (51)
- Iron release and erythrocyte damage in allyl alcohol intoxication in mice. (1990) (50)
- Effects of weight loss on liver and erythrocyte polyunsaturated fatty acid pattern and oxidative stress status in obese patients with non-alcoholic fatty liver disease. (2008) (50)
- Allyl alcohol-induced hemolysis and its relation to iron release and lipid peroxidation. (1989) (48)
- Release of mercury from dental amalgam and its influence on salivary antioxidant activity. (2000) (48)
- Inhibition of calcium sequestration activity of liver microsomes by 4-hydroxyalkenals originating from the peroxidation of liver microsomal lipids. (1984) (47)
- Iron release, superoxide production and binding of autologous IgG to band 3 dimers in newborn and adult erythrocytes exposed to hypoxia and hypoxia-reoxygenation. (2004) (45)
- Hemolytic drugs aniline and dapsone induce iron release in erythrocytes and increase the free iron pool in spleen and liver. (1999) (42)
- Purification and characterization of glutathione-dependent dehydroascorbate reductase from rat liver. (1997) (41)
- Oxidative stress, isoprostanes and hepatic fibrosis. (2009) (40)
- Protection by ascorbate against apoptosis of thymocytes: implications of ascorbate-induced nonlethal oxidative stress and poly(ADP-ribosyl)ation. (1996) (39)
- On a possible role for glucose-6-phosphatase in the regulation of liver cell cytosolic calcium concentration (1986) (37)
- Role of caspases-3 and -7 in Apaf-1 proteolytic cleavage and degradation events during cisplatin-induced apoptosis in melanoma cells. (2004) (37)
- Protection of erythrocytes against oxidative damage and autologous immunoglobulin G (IgG) binding by iron chelator fluor-benzoil-pyridoxal hydrazone. (2000) (36)
- Redox modulation of protein kinase/phosphatase balance in melanoma cells: the role of endogenous and gamma-glutamyltransferase-dependent H2O2 production. (2003) (36)
- Calcium sequestration activity in rat liver microsomes. Evidence for a cooperation of calcium transport with glucose-6-phosphatase. (1985) (36)
- FREE RADICALS, OXIDATIVE STRESS AND ANTIOXIDANTS (2010) (36)
- Iron release, lipid peroxidation, and morphological alterations of erythrocytes exposed to acrolein and phenylhydrazine. (1994) (34)
- Introduction-serial review: iron and cellular redox status. (2002) (29)
- 4-Hydroxynonenal and other lipid peroxidation products are formed in mouse liver following intoxication with allyl alcohol. (1988) (29)
- Effects of carbonyl compounds (4-hydroxyalkenals) originating from the peroxidation of liver microsomal lipids on various microsomal enzyme activities of the liver. (1980) (28)
- Studies on the relatipnships between carbon tetrachloride-induced alterations of liver microsomal lipids and impairment of glucose-6-phosphatase activity. (1977) (28)
- Determination of 4-hydroxynonenal by high-performance liquid chromatography with electrochemical detection (1993) (28)
- A study of the relationships between carbon tetrachloride-induced lipid peroxidation and liver damage in rats pretreated with vitamin E. (1974) (27)
- Iron released from an erythrocyte lysate by oxidative stress is diffusible and in redox active form (1993) (27)
- Fatty acid composition of mitochondrial and microsomal lipids of rat liver after acute ethanol intoxication. (1971) (27)
- Isoprostanes and hepatic fibrosis. (2008) (27)
- Modulation of human T lymphocyte proliferation by 4-hydroxynonenal, the bioactive product of neutrophil-dependent lipid peroxidation. (1997) (26)
- Signaling pathways involved in isoprostane-mediated fibrogenic effects in rat hepatic stellate cells. (2013) (26)
- Extra‐cellular thiol metabolism in clones of human metastatic melanoma with different gamma‐glutamyl transpeptidase expression: Implications for cell response to platinum‐based drugs (2002) (23)
- F2-isoprostane receptors on hepatic stellate cells (2008) (23)
- Possible role of membrane gamma-glutamyltransferase activity in the facilitation of transferrin-dependent and -independent iron uptake by cancer cells. (2003) (23)
- Protection by ascorbic acid against oxidative injury of isolated hepatocytes. (1994) (22)
- Lipid Peroxidation. An Overview (1993) (22)
- Foot-edema induced by carbonyl compounds originating from the peroxidation of liver microsomal lipids. (1980) (22)
- Redox Modulation of NF-κB Nuclear Translocation and DNA Binding in Metastatic Melanoma. The Role of Endogenous and γ-Glutamyl Transferase-Dependent Oxidative Stress (2003) (22)
- Early alterations induced by carbon tetrachloride in the lipids of the membranes of the endoplasmic reticulum of the liver cell. I. Separation and partial characterization of altered lipids. (1977) (21)
- Liver glutathione peroxidase activity and CCl4-induced lipid peroxidation in selenium treated rats. (1974) (20)
- Oxidants in biology: a question of balance (2008) (20)
- REGULATION OF ASCORBIC ACID AND OF XYLULOSE SYNTHESIS IN RAT-LIVER EXTRACTS. THE EFFECT OF STARVATION ON THE ENZYMES OF THE GLUCURONIC ACID PATHWAY. (1965) (19)
- Oxidative stress, erythrocyte ageing and plasma non-protein-bound iron in diabetic patients (2008) (19)
- Stimulatory effect of glucose 6-phosphate on the non-mitochondrial Ca2+ uptake in permeabilized hepatocytes and Ca2+ release by inositol trisphosphate. (1987) (19)
- Carbon tetrachloride induced peroxidation of liver lipids in vitamin E pretreated rats. (1972) (18)
- Oxidative stress and autologous immunoglobulin G binding to band 3 dimers in newborn erythrocytes. (2006) (18)
- Imaging of oxidative stress at subcellular level by confocal laser scanning microscopy after fluorescent derivatization of cellular carbonyls. (1993) (18)
- Iron release in erythrocytes from patients with beta-thalassemia. (1999) (18)
- Binding of products originating from the peroxidation of liver microsomal lipids to the non-lipid constituents of the microsomal membrane. (1979) (16)
- Glutathione Depletion, Lipid Peroxidation, and Liver Necrosis following Bromobenzene and lodobenzene Intoxication (1984) (16)
- Iron mobilization from crocidolite as enhancer of collagen content in rat lung fibroblasts. (1997) (15)
- Early mitochondrial disfunction in bromobenzene treated mice: a possible factor of liver injury. (1990) (15)
- Effects of cicloxilic acid on CCl4-induced liver injury. (1978) (14)
- The direct effect of carbon tetrachloride on subcellular particles. (1966) (14)
- Lipid peroxidation, protein thiols and calcium homeostasis in bromobenzene-induced liver damage. (1988) (13)
- Single-cell investigation by laser scanning confocal microscopy of cytochemical alterations resulting from extracellular oxidant challenge (1996) (13)
- Changes in fatty acid pattern of liver microsomal phospholipids in rats treated with carbon tetrachloride. (1971) (12)
- Cisplatin‐Induced Apoptosis in Melanoma Cells (2003) (12)
- Carbon tetrachloride induced liver alterations in rats pretreated with N,N'-diphenyl-p-phenylenediamine. (1974) (12)
- Studies on in vitro peroxidation of liver lipids in ethanol-treated rats (1973) (10)
- Determination of a Redox Compensation Index and Its Relationships to Glycaemic Control in Type 2 Diabetes Mellitus (2000) (9)
- Selective colocalization of lipid peroxidation and protein thiol loss in chemically induced hepatic preneoplastic lesions: the role of γ-glutamyltranspeptidase activity (1996) (9)
- Alterations of hepatocyte Ca2+ homeostasis by triethylated lead (Et3Pb+): are they correlated with cytotoxicity? (1994) (7)
- The use of 3-hydroxy-2-naphthoic acid hydrazide and Fast Blue B for the histochemical detection of lipid peroxidation in animal tissues — a microphotometric study (2004) (7)
- On the mechanisms of the inhibition of calcium sequestering activity of liver microsomes in bromotrichloromethane intoxication. (1984) (7)
- Characterization of the early molecular alterations of liver microsomal lipids following CCl4 intoxication. (1976) (6)
- Adaptive regulation of ascorbic acid synthesis in rat-liver extracts. Effect of x-irradiation and of dietary changes. (1963) (6)
- Reactive Aldehydes (4-Hydroxyalkenals) Originating from the Peroxidation of Liver Microsomal Lipids: Biological Effects and Evidence for their Binding to Microsomal Protein in CCl4 or BrCCl3 Intoxication1 (1984) (6)
- On the role of lipid peroxidation and protein-bound aldehydes in the haloalkane-induced inactivation of microsomal glucose 6 phosphatase. (1990) (5)
- Iron and Erythrocytes: Physiological and Pathophysiological Aspects (2008) (5)
- The use of 3-hydroxy-2-naphthoic acid hydrazide and Fast Blue B for the histochemical detection of lipid peroxidation in animal tissues — a microphotometric study (2004) (4)
- REGULATION OF ASCORBIC ACID AND OF XYLULOSE SYNTHESIS IN LIVER EXTRACTS. THE EFFECT OF STARVATION IN VARIOUS ANIMALS. (1965) (4)
- Detection of 4-Hydroxynonenal and Other Lipid Peroxidation Products in the Liver of Allyl Alcohol-Intoxicated Mice (1988) (4)
- Lipid Alterations of Liver Microsomal Fraction and Plasma Lipoproteins after Carbon Tetrachloride Poisoning (1973) (4)
- Regulation of Ascorbic Acid Synthesis in Rat-liver Extracts : Experiments with Growing Rats (1964) (3)
- Changes in microsomal lipids of rat liver after chronic carbon tetrachloride intoxication (1971) (3)
- Regulation of ascorbic acid and of xylulose synthesis in rat-liver extracts. The effect of alloxan-diabetes on the glucuronic acid pathway. (1965) (3)
- Bromotrichloromethane-induced damage to bronchiolar Clara cells. (1987) (3)
- Acrolein or phenylhydrazine-induced iron release and its relationships with oxidative damage in erythrocytes (1990) (2)
- On the mechanisms of the CCl4-induced inhibition of liver cytochrome P-450. (1987) (2)
- Variations of fatty acid composition of erythrocyte and plasma lipids in the rat during the first period of life (1983) (2)
- The role of vitamin E in the hepatotoxicity by glutathione depleting agents. (1990) (2)
- F2-Isoprostane receptors and signal transduction on hepatic stellate cells (2008) (2)
- Hepatocyte grafting as an alternative to liver transplant. (2001) (1)
- An in vivo model of hyperacute rejection: characterization and evaluation of the effect of transgenic human complement inhibitors (2000) (1)
- Limitation of myocardial oxygen uptake under acetyl-beta-methylcholine. (1967) (1)
- [Ascorbic acid content of certain rat organs and urine in experimental alloxan diabetes]. (1966) (1)
- [Stimulation of the lipid peroxidation of rat liver homogenates by low concentration of CC1-4 in vitro]. (1965) (1)
- OXIDATIVE MODIFICATION OF LIPOPROTEINS IN ATHEROSCLEROSIS. AN OVERVIEW (1991) (1)
- [Effect of reduced glutathione on carbon tetrachloride induced fatty liver: various considerations]. (1981) (1)
- Lipid Peroxidation, Protein Thiols, Calcium Homeostasis and Imbalance of Antioxidant Systems in Bromobenzene Induced Liver Damage (1988) (1)
- [Inactivation of microsomal glucose-6-phosphatase coupled to the peroxidation of liver microsome lipids in compartmentalized systems]. (1977) (1)
- [Interactions between the products of peroxidation of liver microsome lipids and the non-lipid membrane components. Preliminary results]. (1977) (0)
- Technical Advances Imaging of Oxidative Stress at Subcellular Level by Confocal Laser Scanning Microscopy after Fluorescent Derivativization of Cellular Carbonyls (2007) (0)
- F2-Isoprostanes as markers of oxidative stress and mediators of CCl4-induced liver fibrosis (2010) (0)
- Lipid Peroxidation and Cellular Damage in Extra hepatic Tissues of Bromo benzene-Intoxicated Mice (2007) (0)
- [Relationship between various antioxidant systems in hepatic cells during bromobenzene poisoning]. (1988) (0)
- Histochemistry of lipid peroxidation in pre-neoplastic and toxic liver injury (1990) (0)
- Hepatic Iron Overload Induced by Phenylhydrazine: Release of Iron in a Free Form and DNA Damage (1996) (0)
- Iron from crocidolite asbestos stimulates collagen production in rat lung fibroblasts (1995) (0)
- Review Oxidative stress, isoprostanes and hepatic fibrosis (2009) (0)
- F2-Isoprostanes: Markers and Mediators of an Imbalanced Redox Status in the Liver (2008) (0)
- Intoxication Glutathione Depletion, Lipid Peroxidation, and Liver Necrosis following Bromobenzene and lodobenzene (2011) (0)
- [Protective action of EDTA on inactivation by CCl-4 in vitro of microsome glucose-6-phosphatase]. (1965) (0)
- [Changes in the fatty acid composition of lipids from the liver and hepatic microsomes of rats with carbon tetrachloride poisoning]. (1969) (0)
- [Effect of some cations on the inactivation by CCl-4 of microsomial glucose-6-phosphatase in vitro]. (1966) (0)
- Phenylhydrazine-induced iron release as a mechanism of membrane and DNA damage (1993) (0)
- Chapter 17 F 2 -Isoprostanes: Markers and Mediators of an Imbalanced Redox Status in the Liver (2008) (0)
- [Functional coupling of the calcium pump and glucose 6-phosphatase activity in liver microsomes: preliminary results]. (1984) (0)
- [Depletion of liver glutathione induced by iodobenzene poisoning and its relation to lipid peroxidation and necrosis]. (1983) (0)
- [Autoregulation of the coronary circulation. I. Experimental study with "isolated heart in situ" preparation in the dog under chloralose anesthesia]. (1962) (0)
- Fibrogenic effects of isoprostanes on hepatic stellate cells are mediated by TP receptor (2008) (0)
- Allyl Alcohol, Acrolein and Haemolysis (1989) (0)
- Evidence for the Coupling of Calcium Transport with Glucose 6-Phosphatase Activity in Rat Liver Microsomes (1986) (0)
- Effect of cicloxilic acid on the liver damage produced by a choline-free, high-fat low-protein diet. (1978) (0)
- Xenobiotics, free radicals and cell membranes (1998) (0)
- F2-isoprostanes play a role in Bleomycin-induced lung fibrosis (2014) (0)
- The effect of reduced glutathione on carbon tetra chloride induced fatty liver (1981) (0)
- Release of mercury from dental amalgam and its influence on salivary antioxidant activity. (2000) (0)
- [Inhibition of the calcium-sequestering activity of liver microsomes in monobromotrichloromethane poisoning: preliminary studies on possible mechanisms]. (1984) (0)
- Lipid Peroxidation and Hepatocarcinogenesis: γ-Glutamyl Transpeptidase-Dependent Oxidant Stress in Hepatic Preneoplastic Lesions and HEPG2 Human Hepatoma Cells (1996) (0)
- Fatty acid composition of the major lipid classes of very low density lipoproteins and of plasma in rats poisoned with carbon tetrachloride. (1974) (0)
- [Extraction of dialyzable toxic products produced by peroxidation of hepatic microsomal lipids]. (1978) (0)
- [ADAPTIVE REGULATION OF THE SYNTHESIS OF ASCORBIC ACID AND OF XYLULOSE IN RAT LIVER. COMPETITION BY GULONIC ACID IN FASTING RATS OR RATS FED A CARBOHYDRATE-FREE DIET]. (1963) (0)
- Oxidants and Antioxidants: Ultrastructure and Molecular Biology Protocols (2003) (0)
- Colocalization of oxidized LDL and γ-glutamyl transpeptidase —A potentially prooxidant enzyme - in intimal CD68+ foam cells (1997) (0)
- F2-Isoprostanes and hepatic fibrosis (2004) (0)
- Occurrence of isoprostane receptors activating fibrogenic effects on hepatic stellate cells (2006) (0)
- Hepatic microsomal mixed-function oxidase system in rats pretreated with cicloxilic acid. (1978) (0)
- F2- Isoprostane receptors and hepatic fibrosis (2008) (0)
- [Inhibition of lipid peroxidation by CCl-4 in vitro and in vivo]. (1965) (0)
- F2-Isoprostanes as possibile mediators of CC14-induced hepatic fibrosis. (2004) (0)
- Antioxidants and Prevention of the Hepatocellular Damage Induced by Glutathione-Depleting Agents (1991) (0)
- Richard O. Recknagel. (1993) (0)
- Role of F2-Isoprostanes in lung fibrosis (2008) (0)
- BIOCHEMISTRY AND SIGNAL TRANSDUCTION (1996) (0)
- [Mechanism of action of carbonyl compounds (4-hydroxyalkenals) derived from the peroxidation of hepatic microsomal lipids]. (1981) (0)
- [Cytotoxic effects of carbonyl compounds (4-hydroxyalkenals) derived from peroxidation of hepatic microsomal lipids on isolated hepatocytes]. (1981) (0)
- [Hepatic malonic dialdehyde content in rats pretreated with various antioxidants and intoxicated with carbon tetrachloride]. [Italian] (1975) (0)
- Relationships Between Ascorbic Acid and Glutathione in Antioxidant Defense (1993) (0)
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What Schools Are Affiliated With Mario Comporti?
Mario Comporti is affiliated with the following schools:
