Max Costa
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Max Costamedical Degrees
Medical
#3696
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#4194
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Toxicology
#56
World Rank
#60
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Medical
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(Suggest an Edit or Addition)Max Costa's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Toxicity and carcinogenicity of Cr(VI) in animal models and humans. (1997) (522)
- Mechanisms of chromium carcinogenicity and toxicity. (1993) (516)
- Carcinogenic nickel silences gene expression by chromatin condensation and DNA methylation: a new model for epigenetic carcinogens (1995) (372)
- Toxicity and carcinogenicity of nickel compounds. (1989) (308)
- Carcinogenicity assessment of selected nickel compounds. (1997) (289)
- A simple, sensitive assay to detect DNA-protein crosslinks in intact cells and in vivo. (1992) (247)
- Molecular mechanisms of nickel carcinogenesis. (1994) (246)
- Senescence of nickel-transformed cells by an X chromosome: possible epigenetic control. (1991) (183)
- Formation of the amino acid-DNA complexes by hexavalent and trivalent chromium in vitro: importance of trivalent chromium and the phosphate group. (1996) (159)
- Cr(III)-mediated crosslinks of glutathione or amino acids to the DNA phosphate backbone are mutagenic in human cells. (1998) (147)
- Nickel induces increased oxidants in intact cultured mammalian cells as detected by dichlorofluorescein fluorescence. (1993) (140)
- Nickel-induced transformation shifts the balance between HIF-1 and p53 transcription factors. (1999) (138)
- Glutathione and free amino acids form stable complexes with DNA following exposure of intact mammalian cells to chromate. (1995) (127)
- Genetic toxicology of lead compounds. (1988) (115)
- Molecular mechanisms of nickel carcinogenesis. (1991) (111)
- DNA methylation, heterochromatin and epigenetic carcinogens. (1997) (105)
- Strand breakage and decreased molecular weight of DNA induced by specific metal compounds. (1982) (97)
- Characterization of DNA lesions induced by CaCrO4 in synchronous and asynchronous cultured mammalian cells. (1986) (94)
- DNA-protein cross-links in welders: molecular implications. (1993) (91)
- Mutagenic responses of nickel oxides and nickel sulfides in Chinese hamster V79 cell lines at the xanthine-guanine phosphoribosyl transferase locus. (1993) (90)
- DNA-protein cross-links produced by various chemicals in cultured human lymphoma cells. (1997) (89)
- Analysis of the binding sites of chromium to DNA and protein in vitro and in intact cells. (1992) (86)
- Effects of nickel on DNA methyltransferase activity and genomic DNA methylation levels. (1998) (84)
- Complexing of actin and other nuclear proteins to DNA by cis-diamminedichloroplatinum(II) and chromium compounds. (1991) (82)
- Assessment of the uptake and mutagenicity of nickel chloride in salmonella tester strains. (1986) (82)
- Epigenetic mechanisms of nickel carcinogenesis. (2000) (80)
- Interlaboratory validation of a new assay for DNA-protein crosslinks. (1996) (79)
- Factors influencing the phagocytosis, neoplastic transformation, and cytotoxicity of particulate nickel compounds in tissue culture systems. (1981) (77)
- DNA-protein cross-links induced by nickel compounds in intact cultured mammalian cells. (1985) (75)
- Utilization of DNA-protein cross-links as a biomarker of chromium exposure. (1998) (73)
- DNA-protein complexes induced by chromate and other carcinogens. (1991) (68)
- Differential DNA-protein crosslinking in lymphocytes and liver following chronic drinking water exposure of rats to potassium chromate. (1991) (65)
- Human DNA helicase VIII: a DNA and RNA helicase corresponding to the G3BP protein, an element of the ras transduction pathway. (1999) (64)
- Mechanism of HgCl2 cytotoxicity in cultured mammalian cells. (1984) (61)
- Use of mammalian DNA repair-deficient mutants to assess the effects of toxic metal compounds on DNA. (1984) (59)
- Effect of magnesium on nickel-induced genotoxicity and cell transformation. (1987) (58)
- Molecular mechanisms of nickel carcinogenesis. (2002) (57)
- Incidence and localization of sister chromatid exchanges induced by nickel and chromium compounds. (1986) (56)
- Distribution of chromium within cells of the blood. (1991) (56)
- Analysis of metal-induced DNA lesions and DNA-repair replication in mammalian cells. (1984) (55)
- Toxic metals produce an S-phase-specific cell cycle block. (1982) (50)
- Analysis of the induction of alkali sensitive sites in the DNA by chromate and other agents that induce single strand breaks. (1984) (50)
- Crystalline Ni3S2 specifically enhances the formation of oxidants in the nuclei of CHO cells as detected by dichlorofluorescein. (1994) (48)
- Pathway of nickel uptake influences its interaction with heterochromatic DNA. (1986) (48)
- Conventional radiation-biological dosimetry using frequencies of unstable chromosome aberrations. (1998) (47)
- Nickel enhances telomeric silencing in Saccharomyces cerevisiae. (1999) (44)
- Analysis of residual amino acid--DNA crosslinks induced in intact cells by nickel and chromium compounds. (1992) (43)
- Differences in the effect of vitamin E on nickel sulfide or nickel chloride-induced chromosomal aberrations in mammalian cells. (1991) (43)
- Similarity in the acute cytotoxic response of mammalian cells to mercury (II) and X-rays: DNA damage and glutathione depletion. (1982) (42)
- Heterochromatic proteins specifically enhance nickel-induced 8-oxo-dG formation. (1995) (42)
- Correlations of DNA strand breaks and their repair with cell survival following acute exposure to mercury(II) and X-rays. (1983) (41)
- The histone deacetylase inhibitor trichostatin A reduces nickel-induced gene silencing in yeast and mammalian cells. (2001) (41)
- Protective effect of vitamin E against chromosomal aberrations and mutation induced by sodium chromate in Chinese hamster V79 cells. (1991) (40)
- Characterization of DNA lesions produced by HgCl2 in cell culture systems. (1984) (39)
- Analysis of DNA–protein complexes induced by chemical carcinogens (1990) (38)
- Metal mutagenesis in transgenic Chinese hamster cell lines. (1994) (38)
- Health risk associated with airborne particulate matter and its components in Jeddah, Saudi Arabia. (2017) (37)
- Forward mutations and DNA-protein crosslinks induced by ammonium metavanadate in cultured mammalian cells. (1992) (37)
- Comparison of protein, RNA, and DNA binding and cell-cycle-specific growth inhibitory effects of nickel compounds in cultured cells. (1982) (36)
- A conserved region in human and Chinese hamster X chromosomes can induce cellular senescence of nickel-transformed Chinese hamster cell lines. (1992) (35)
- Model for the epigenetic mechanism of action of nongenotoxic carcinogens. (1995) (32)
- Monitoring human lymphocytic DNA-protein cross-links as biomarkers of biologically active doses of chromate. (1996) (31)
- Preliminary report on a simple new assay for DNA-protein cross-links as a biomarker of exposures experienced by welders. (1993) (30)
- Immunological detection of DNA-protein complexes induced by chromate. (1989) (30)
- Effects of nickel(II) on nuclear protein binding to DNA in intact mammalian cells. (1987) (30)
- Differences in the effects of Hg(II) on DNA repair induced in Chinese hamster ovary cells by ultraviolet or X-rays. (1986) (29)
- RNA binding properties and evolutionary conservation of the Xenopus multifinger protein Xfin. (1993) (28)
- Transformation of human osteoblasts to anchorage-independent growth by insoluble nickel particles. (1994) (27)
- By Releasing ADP, Acanthamoeba castellanii Causes an Increase in the Cytosolic Free Calcium Concentration and Apoptosis in Wish Cells (2001) (26)
- Perspectives on the mechanism of nickel carcinogenesis gained from models of in vitro carcinogenesis. (1989) (26)
- Complexing of amino acids to DNA by chromate in intact cells. (1994) (25)
- Protein oxidation and amino acid-DNA crosslinking by nickel compounds in intact cultured cells. (1994) (23)
- Potentiation of sodium chromate(VI)-induced chromosomal aberrations and mutation by vitamin B2 in Chinese hamster V79 cells. (1992) (22)
- Analysis of proteins cross-linked to DNA after treatment of cells with formaldehyde, chromate, and cis-diamminedichloroplatinum(II). (1989) (21)
- Inhibition of LPS toxicity for macrophages by metallothionein-inducing agents. (1983) (20)
- Growth inhibition and metallothionein induction in cadmium-resistant cells by essential and non-essential metals. (1983) (17)
- A blotting method for monitoring the formation of chemically induced DNA-protein complexes. (1990) (17)
- Application of a modified 203Hg binding assay for metallothionein. (1983) (17)
- Immunodetection of DNA-protein crosslinks by slot blotting. (1990) (16)
- Effect of nickel(II) on DNA-protein binding, thymidine incorporation, and sedimentation pattern of chromatin fractions from intact mammalian cells. (1987) (15)
- Mutagenicity of cobalt and reactive oxygen producers. (1996) (14)
- Alteration in morphology of chinese hamster ovary cells by Ni3S2 and dibutyryl cAMP. (1978) (13)
- Antagonistic effect of magnesium chloride on the nickel chloride-induced inhibition of DNA replication in Chinese hamster ovary cells. (1986) (12)
- Molecular mechanisms of nickel carcinogenesis. (1995) (11)
- Alteration in restriction enzyme digestion patterns detects DNA--protein complexes induced by chromate. (1991) (9)
- Development of an 125I-postlabeling assay as a simple, rapid, and sensitive index of DNA-protein cross-links. (1994) (9)
- Hodgkin's disease in association with hexavalent chromium exposure. (1996) (8)
- Cloning, sequencing and functional expression of a DNA encoding pig cytosolic malate dehydrogenase: purification and characterization of the recombinant enzyme. (1996) (7)
- Molecular targets of nickel and chromium in human and experimental systems. (1993) (5)
- Carcinogenic Inorganic Chemicals (2010) (4)
- Third International Meeting on the Molecular Mechanisms of Metal Toxicity and Carcinogenicity (2002) (2)
- The detection of DNA-protein complexes in vitro by an immunological assay. (1990) (2)
- DNA-protein crosslinks as a biomarker of cis-platinum activity in cancer patients. (1996) (2)
- Phosphorylation of nuclear and DNA-binding proteins in proliferating and quiescent mammalian cells. (1981) (1)
- Community health perceptions and human environmental exposure to chromium contamination in a small New Jersey City. (2019) (1)
- In vitro and in vivo carcinogenesis of metals and their coumpounds produced by coal combustion. Progress report (1982) (0)
- Protective effects of MgCl/sub 2/ on NiCl/sub 2/ - induced transformation, chromosomal aberrations and inhibition of DNA replication (1986) (0)
- Carcinogenic metals. (1998) (0)
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Max Costa is affiliated with the following schools:
