Michael D. Pierschbacher
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Michael D. Pierschbacherbiology Degrees
Biology
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Cell Biology
#316
World Rank
#324
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Biology
Why Is Michael D. Pierschbacher Influential?
(Suggest an Edit or Addition)Michael D. Pierschbacher's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- New perspectives in cell adhesion: RGD and integrins. (1987) (4624)
- Cell attachment activity of fibronectin can be duplicated by small synthetic fragments of the molecule (1984) (3366)
- Arg-Gly-Asp: A versatile cell recognition signal (1986) (1274)
- Identification and isolation of a 140 kd cell surface glycoprotein with properties expected of a fibronectin receptor (1985) (1027)
- Natural inhibitor of transforming growth factor-β protects against scarring in experimental kidney disease (1992) (1018)
- Platelet membrane glycoprotein IIb/IIIa: member of a family of Arg-Gly-Asp--specific adhesion receptors. (1986) (851)
- Variants of the cell recognition site of fibronectin that retain attachment-promoting activity. (1984) (667)
- Influence of stereochemistry of the sequence Arg-Gly-Asp-Xaa on binding specificity in cell adhesion. (1987) (614)
- The effect of Arg-Gly-Asp-containing peptides on fibrinogen and von Willebrand factor binding to platelets. (1985) (552)
- Amino acid sequence of the human fibronectin receptor (1987) (550)
- Fibronectin: purification, immunochemical properties, and biological activities. (1982) (521)
- Degradation of decorin by matrix metalloproteinases: identification of the cleavage sites, kinetic analyses and transforming growth factor-beta1 release. (1997) (471)
- A 125/115-kDa cell surface receptor specific for vitronectin interacts with the arginine-glycine-aspartic acid adhesion sequence derived from fibronectin. (1985) (442)
- Serum spreading factor (vitronectin) is present at the cell surface and in tissues. (1983) (412)
- Location of the cell-attachment site in fibronectin with monoclonal antibodies and proteolytic fragments of the molecule (1981) (399)
- Complete amino acid sequence of human vitronectin deduced from cDNA. Similarity of cell attachment sites in vitronectin and fibronectin. (1985) (352)
- Vitronectin--a major cell attachment-promoting protein in fetal bovine serum. (1985) (323)
- Inhibition of in vitro tumor cell invasion by Arg-Gly-Asp-containing synthetic peptides [published erratum appears in J Cell Biol 1989 Jun;108(6):following 2546] (1988) (299)
- Disialogangliosides GD2 and GD3 are involved in the attachment of human melanoma and neuroblastoma cells to extracellular matrix proteins (1986) (290)
- A cell surface receptor complex for collagen type I recognizes the Arg- Gly-Asp sequence (1987) (284)
- Detachment of cells from culture substrate by soluble fibronectin peptides (1985) (283)
- Alpha 2 beta 1 integrins from different cell types show different binding specificities. (1990) (245)
- A novel integrin specificity exemplified by binding of the alpha v beta 5 integrin to the basic domain of the HIV Tat protein and vitronectin (1993) (244)
- An Arg-Gly-Asp-directed receptor on the surface of human melanoma cells exists in an divalent cation-dependent functional complex with the disialoganglioside GD2 (1987) (235)
- Identification of a bone sialoprotein receptor in osteosarcoma cells. (1988) (232)
- Synthetic peptide with cell attachment activity of fibronectin. (1983) (207)
- Deposition of plasma fibronectin in tissues. (1981) (205)
- cDNA and amino acid sequences of the cell adhesion protein receptor recognizing vitronectin reveal a transmembrane domain and homologies with other adhesion protein receptors. (1986) (202)
- Amino acid sequence of the vitronectin receptor alpha subunit and comparative expression of adhesion receptor mRNAs. (1987) (200)
- [27] Arginine-glycine-aspartic acid adhesion receptors (1987) (198)
- Inhibition of fibronectin binding to platelets by proteolytic fragments and synthetic peptides which support fibroblast adhesion. (1985) (171)
- Antifibrotic effect of decorin in a bleomycin hamster model of lung fibrosis. (1997) (167)
- The cell attachment domain of fibronectin. Determination of the primary structure. (1982) (161)
- Calcium as a potential physiological regulator of integrin-mediated cell adhesion. (1991) (160)
- Extracellular matrices and cell adhesion. (1985) (151)
- Molecular cloning and sequence analysis of a chondroitin sulfate proteoglycan cDNA. (1985) (148)
- Arginyl-glycyl-aspartic acid sequences and fibrinogen binding to platelets. (1987) (148)
- Domain structure of vitronectin. Alignment of active sites. (1984) (143)
- Design and synthesis of novel cyclic RGD-containing peptides as highly potent and selective integrin alpha IIb beta 3 antagonists. (1994) (131)
- Cell attachment on replicas of SDS polyacrylamide gels reveals two adhesive plasma proteins (1982) (131)
- Shifts in the concentrations of magnesium and calcium in early porcine and rat wound fluids activate the cell migratory response. (1995) (127)
- Regulation of alpha 2 beta 1-mediated fibroblast migration on type I collagen by shifts in the concentrations of extracellular Mg2+ and Ca2+ [published erratum appears in J Cell Biol 1992 Jul;118(1):219] (1992) (115)
- Immunochemical and amino-terminal sequence comparison of two cytoadhesins indicates they contain similar or identical beta subunits and distinct alpha subunits. (1987) (114)
- Integrin αIIbβ3 Inhibitor Preserves Microvascular Patency in Experimental Acute Focal Cerebral Ischemia (2000) (108)
- cDNA sequences from the alpha subunit of the fibronectin receptor predict a transmembrane domain and a short cytoplasmic peptide. (1986) (100)
- Human osteosarcoma cells resistant to detachment by an Arg-Gly-Asp- containing peptide overproduce the fibronectin receptor (1987) (97)
- Arginine-glycine-aspartic acid adhesion receptors. (1987) (97)
- Cation-dependent changes in the binding specificity of the platelet receptor GPIIb/IIIa. (1990) (96)
- Concept and progress in the development of RGD‐containing peptide pharmaceuticals (1995) (83)
- Chondroitin/dermatan sulfate proteoglycan in human fetal membranes. Demonstration of an antigenically similar proteoglycan in fibroblasts. (1984) (81)
- The cell attachment determinant in fibronectin (1985) (76)
- Enhancement of cell interactions with collagen/glycosaminoglycan matrices by RGD derivatization. (1997) (75)
- Integrin alpha(IIb)beta(3) inhibitor preserves microvascular patency in experimental acute focal cerebral ischemia. (2000) (64)
- T-lymphocyte differentiation and the extracellular matrix: identification of a thymocyte subset that attaches specifically to fibronectin. (1986) (59)
- Identification of fibronectin receptors on T lymphocytes (1987) (56)
- Preferential expression of fibronectin receptors on immature thymocytes (1988) (55)
- Changes in the Concentrations of Extracellular Mg++ and Ca++ Down-Regulate E-Cadherin and Up-Regulate α2β1 Integrin Function, Activating Keratinocyte Migration on Type I Collagen (1995) (54)
- Structure of fibronectin and its fragments in electron microscopy. (1982) (49)
- Induction of T-cell maturation by a cloned line of thymic epithelium (TEPI). (1983) (47)
- Fibronectin: a molecule with remarkable structural and functional diversity (1982) (45)
- Manipulation of cellular interactions with biomaterials toward a therapeutic outcome: A perspective (1994) (45)
- Molecular and biological interactions of fibronectin. (1982) (36)
- Comparison of two phosphoproteins in chicken bone and their similarities to the mammalian bone proteins, osteopontin and bone sialoprotein II. (1990) (34)
- Glioma cell integrin expression and their interactions with integrin antagonists: Research Article. (2005) (34)
- Inhibition of coronary artery reocclusion after thrombolysis with an RGD‐containing peptide with no significant effect on bleeding time (1993) (34)
- The osteoblast-like differentiated phenotype of a variant of MG-63 osteosarcoma cell line correlated with altered adhesive properties. (1989) (33)
- Purification and characterization of vitronectin. (1987) (33)
- [12] Role of transforming growth factor β and decorin in controlling fibrosis (1994) (32)
- Expression of functional α4β1 integrin by human dermal fibroblasts (1993) (32)
- Cell Attachment and Motility on Materials Modified by Surface‐active RGD‐containing Peptides (1994) (31)
- A Novel Integrin Specificity Exemplified by Binding of the av/35 Integrin to the Basic Domain of the HIV Tat Protein and Vitronectin (2002) (30)
- The cysteine protease cathepsin B is a key drug target and cysteine protease inhibitors are potential therapeutics for traumatic brain injury. (2015) (30)
- Effects of an arginine-glycine-aspartic acid peptide-containing artificial matrix on epithelial migration in vitro and experimental second-degree burn wound healing in vivo. (1996) (29)
- Changes in the concentrations of extracellular Mg++ and Ca++ down-regulate E-cadherin and up-regulate alpha 2 beta 1 integrin function, activating keratinocyte migration on type I collagen. (1995) (28)
- Accelerated healing of cardiovascular textiles promoted by an RGD peptide. (1995) (26)
- Selective alpha IIb beta 3 receptor blockage with peptide TP9201 prevents platelet uptake on Dacron vascular grafts without significant effect on bleeding time. (1994) (24)
- Incorporation of thioether building blocks into an αvβ3‐specific RGD peptide: Synthesis and biological activity (2003) (20)
- A 30 kD sulfated extracellular matrix protein immunologically crossreactive with vitronectin. (1993) (20)
- An adhesion variant of the MG-63 osteosarcoma cell line displays an osteoblast-like phenotype. (1988) (16)
- Expression of functional alpha 4 beta 1 integrin by human dermal fibroblasts. (1993) (14)
- Role of transforming growth factor beta and decorin in controlling fibrosis. (1994) (14)
- Incorporation of (2S,3S) and (2S,3R) beta-methyl aspartic acid into RGD-containing peptides. (2002) (14)
- Inhibition of Thrombosis by a Selective Fibrinogen Receptor Antagonist without Effect on Bleeding Time (1994) (12)
- Cellular Interaction with Biomaterials Modified by Arg-Gly-Asp Containing Peptides (1991) (9)
- [26] Therapeutic application of matrix biology (1994) (9)
- Receptor-bound conformation of an alpha(5)beta(1) integrin antagonist by (15)N-edited 2D transferred nuclear overhauser effects. (2002) (9)
- A phosgeneless synthesis of diaryl carbonates (1976) (7)
- BIOLOGICAL ACTIVITY OF THE PURE THYMUS PROTEIN, LSHr (1979) (3)
- Incorporation of thioether building blocks into an alphavbeta3-specific RGD peptide: synthesis and biological activity. (2003) (3)
- Integrin a IIb b 3 Inhibitor Preserves Microvascular Patency in Experimental Acute Focal Cerebral Ischemia (2000) (3)
- THE ARG-GLY-ASP(SER) SEQUENCE OF FIBRONECTIN, AND THE GLYCOPROTEIN IIB-IIIA COMPLEX ARE NOT INVOLVED IN FIBRONECTIN DEPENDENT PLATELET ADHESION IN FLOW (1987) (2)
- Therapeutic application of matrix biology. (1994) (2)
- Design & synthesis of novel cyclic rgd peptides as highly potent & selective GPIIb/IIIa antagonists (1994) (2)
- Fibronectin Receptor Expression on Thymocytes (1990) (1)
- Studies of the receptor‐bound conformation of αIIbβ3 antagonists by 15N‐edited NMR spectroscopy (2002) (1)
- Plasma Fibronectin: Structure and Function.Jan McDonagh (1987) (1)
- A process for the manufacture of stabilized cell adhesion peptides conformationnell (1988) (0)
- Polypeptide-polymer conjugates having a wound healing effect (1989) (0)
- A cell adhesion peptide that supports tissue interactions on inert materials (1993) (0)
- Studies of the receptor-bound conformation of alphaIIbbeta3 antagonists by 15N-edited NMR spectroscopy. (2002) (0)
- Inventor : 73 ) Assignee : 11 Patent Number : 45 ) Date of Patent : 4 , 789 , 734 Dec . 6 , 1988 Thiol-Sensitive Sites in Cell Adhesion (2017) (0)
- Method and compound for the treatment of thrombosis (1991) (0)
- Hydrophobic binding site for adhesion peptides. (1990) (0)
- A polypeptide-polymer conjugates that are active in wound healing (1991) (0)
- Investigation on the Structural Requirements for Binding Integrin α IIb β 3 (2001) (0)
- Results Immunologic Relationship between the Fibronectin Receptors on T Lymphocytes and Those on Fibroblastic Cells (1987) (0)
- In vitro induction of E-rosette formation in human bone marrow cells by the thymic proteins LSHr and LSHh. (1979) (0)
- Cathepsin B gene deletion and cysteine protease inhibition are effective in a traumatic brain injury model (2012) (0)
- THE EXPRESSION AND FUNCTION OF INTEGRIN ADHESION MOLECULES ON HUMAN ISLET CELLS: DEVELOPING A NOVEL APPROACH TO ISLET TRANSPLANTATION (1997) (0)
- Receptor-bound conformations of integrin α IIb β 3 antagonists by 15 N-edited NMR spectroscopy (2002) (0)
- United States Patent ( 19 ) Charo et al . 54 PEPTIDES DERIVED FROM GPA ( 75 ) Inventors : Israel (2017) (0)
- Concept and progress in the development of RGD‐containmg peptide pharmaceuticals (0)
- Inhibitor of cell transfer comprising synthetic peptide (1989) (0)
- The α5β1 integrin in tumour suppression : Metastases (1994) (0)
- Molecular cloning and sequence analysis of a chondroitin sulfate proteoglycan cDNA ( extracellular matrix / cell adhesion / glycosylation ) (2003) (0)
- E64d treatment improves outcomes in animal models of traumatic brain injury, ischemia and Alzheimer's disease through inhibiting cathepsin B (2013) (0)
- Assay using synthetic peptide (1996) (0)
- Procede et composition de traitement de la thrombose (1991) (0)
- Active adhesion peptide (1990) (0)
- Imagerie par resonance magnetique utilisee detecter un thrombus (1997) (0)
- Polypeptide polymer-ion complex having activity to wound healing (1991) (0)
- Polypeptide-polymer conjugates for treating wounds. (1989) (0)
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What Schools Are Affiliated With Michael D. Pierschbacher?
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