Marcel E. Nimni
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Developmental Biology
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Cell Biology
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Molecular Biology
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Biology
Why Is Marcel E. Nimni Influential?
(Suggest an Edit or Addition)Marcel E. Nimni's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Independent regulation of collagen types by chondrocytes during the loss of differentiated function in culture (1978) (562)
- Chemically modified collagen: a natural biomaterial for tissue replacement. (1987) (381)
- Proanthocyanidin: a natural crosslinking reagent for stabilizing collagen matrices. (2003) (335)
- Biochemical changes and cytotoxicity associated with the degradation of polymeric glutaraldehyde derived crosslinks. (1990) (324)
- The progeny of rabbit articular chondrocytes synthesize collagen types I and III and type I trimer, but not type II. Verifications by cyanogen bromide peptide analysis. (1977) (299)
- Polypeptide growth factors: targeted delivery systems. (1997) (268)
- Collagen: structure, function, and metabolism in normal and fibrotic tissues. (1983) (255)
- Modulation of Collagen Synthesis by Transforming Growth Factor‐β in Keloid and Hypertrophic Scar Fibroblasts (1994) (198)
- Mechanism of crosslinking of proteins by glutaraldehyde III. Reaction with collagen in tissues. (1985) (197)
- Collagen types. Molecular structure and tissue distribution. (1992) (185)
- Toxic reactions evoked by glutaraldehyde-fixed pericardium and cardiac valve tissue bioprosthesis. (1984) (180)
- Mechanism of crosslinking of proteins by glutaraldehyde II. Reaction with monomeric and polymeric collagen. (1982) (180)
- In vitro fibroplasia: matrix contraction, cell growth, and collagen production of fibroblasts cultured in fibrin gels. (1996) (179)
- Chitosan/gelatin-based films crosslinked by proanthocyanidin. (2005) (165)
- Collagen Shortening: An Experimental Approach With Heat (1997) (163)
- The effect of gamma-irradiation on collagen molecules, isolated alpha-chains, and crosslinked native fibers. (1990) (160)
- Differences in Collagen Metabolism between Normal and Osteoarthritic Human Articular Cartilage (1973) (158)
- The effect of thrombin activation of platelet-rich plasma on demineralized bone matrix osteoinductivity. (2009) (144)
- A defect in the intramolecular and intermolecular cross-linking of collagen caused by penicillamine. II. Functional groups involved in the interaction process. (1969) (144)
- A recombinant human TGF-beta1 fusion protein with collagen-binding domain promotes migration, growth, and differentiation of bone marrow mesenchymal cells. (1999) (137)
- A defect in the intramolecular and intermolecular cross-linking of collagen caused by penicillamine. I. Metabolic and functional abnormalities in soft tissues. (1968) (132)
- Properties of a collagen molecule containing three identical components extracted from bovine articular cartilage. (1971) (132)
- Are we getting enough sulfur in our diet? (2007) (130)
- Mechanism of crosslinking of proteins by glutaraldehyde I: reaction with model compounds. (1982) (117)
- Relative distribution and crosslinking of collagen distinguish fetal from adult sheep wound repair. (1999) (115)
- Collagen defect induced by penicillamine. (1965) (112)
- Quantitative and sensitive in vitro assay for osteoinductive activity of demineralized bone matrix (2003) (108)
- Stimulation of fibroblast biosynthetic activity by serum of patients with pretibial myxedema. (1978) (100)
- Elevated levels of plasminogen activator inhibitor-1 may account for the altered fibrinolysis by keloid fibroblasts. (1996) (95)
- The synergetic effect of hydrogel stiffness and growth factor on osteogenic differentiation. (2014) (91)
- In vitro collagen biosynthesis in healing and normal rabbit articular cartilage. (1978) (82)
- Role of Growth Factors in Scar Contraction: An In Vitro Analysis (1996) (81)
- Abnormalities in the Biosynthesis of Cartilage and Bone Proteoglycans in Experimental Diabetes (1981) (80)
- Biochemical composition of collagen in continent and stress urinary incontinent women. (1994) (79)
- Dermal fibroblasts activate keratinocyte outgrowth on collagen gels. (1994) (77)
- Type I collagen and fibronectin synthesis by retrocorneal fibrous membrane. (1982) (73)
- Promotion of calvarial cell osteogenesis by endothelial cells (1990) (72)
- Increase in fibronectin in the deep dermis of involved skin in progressive systemic sclerosis. (1979) (70)
- Complement proteins are present in developing endochondral bone and may mediate cartilage cell death and vascularization. (1996) (67)
- Collagen: Its structure and function in normal and pathological connective tissues. (1974) (60)
- Calcitonin stimulates bone formation when administered prior to initiation of osteogenesis. (1981) (60)
- Characterization of the aldehydes present on the cyanogen bromide peptides from mature rat skin collagen. (1971) (60)
- Demineralized bone matrix mediates differentiation of bone marrow stromal cells in vitro: Effect of age of cell donor (1996) (58)
- The stability of the collagen phenotype during stimulated collagen, glycosaminoglycan, and DNA synthesis by articular cartilage organ cultures. (1979) (58)
- The effect of aging on bone formation in rats: Biochemical and histological evidence for decreased bone formation capacity (1985) (58)
- Cell delivery using an injectable and adhesive transglutaminase-gelatin gel. (2010) (57)
- New collagen markers of 'derepression' synthesized by rabbit articular chondrocytes in culture. (1976) (53)
- The presence of intermolecular disulfide cross-links in type III collagen. (1983) (53)
- The molecular organization of collagen and its role in determining the biophysical properties of the connective tissues. (1980) (52)
- Changes in collagen metabolism associated with the administration of penicillamine and various amino and thiol compounds. (1969) (50)
- Collagen Synthesis and Turnover in the Growing Rat Under the Influence of Methyl Prednisolone.∗ (1964) (50)
- Accumulation of a collagen precursor in the skin of penicillamine-treated rats. (1965) (48)
- Delivery of demineralized bone matrix powder using a thermogelling chitosan carrier. (2012) (47)
- Osteogenesis in bone defects in rats: the effects of hydroxyapatite and demineralized bone matrix. (1989) (47)
- Mechanism of Inhibition of Collagen Crosslinking by Penicillamine (1977) (46)
- Factors which affect the calcification of tissue-derived bioprostheses. (1997) (46)
- Selection and amplification of a bone marrow cell population and its induction to the chondro-osteogenic lineage by rhOP-1: an in vitro and in vivo study. (2001) (45)
- Chondroitin sulfate and other sulfate containing chondroprotective agents may exhibit their effects by overcoming a deficiency of sulfur amino acids. (2003) (45)
- Mechanism of crosslinking of proteins by glutaraldehyde. IV: In vitro and in vivo stability of a crosslinked collagen matrix. (1990) (44)
- Synthesis and turnover of collagen precursors in rabbit skin. (1967) (44)
- Human endothelial cells are defective in diabetic vascular disease. (1994) (43)
- Capture and expansion of bone marrow-derived mesenchymal progenitor cells with a transforming growth factor-beta1-von Willebrand's factor fusion protein for retrovirus-mediated delivery of coagulation factor IX. (1997) (43)
- Engineering, Expression, and Renaturation of a Collagen-Targeted Human bFGF Fusion Protein (2001) (43)
- Influence of high protein diets on cartilage and bone formation in rats. (1981) (43)
- Coordinate regulation of type IX and type II collagen synthesis during growth of chick chondrocytes in retinoic acid or 5-bromo-2'-deoxyuridine. (1986) (42)
- Intra-articular injection of collagenase induced experimental osteoarthritis of the lumbar facet joint in rats (2008) (42)
- Engineering, expression and renaturation of targeted TGF-beta fusion proteins. (1996) (42)
- Effects of hyaluronan on collagen fibrillar matrix contraction by fibroblasts. (1994) (41)
- New evidence and new hope concerning endothelial seeding of vascular grafts. (1992) (40)
- Basement membrane collagen synthesis by rabbit corneal endothelial cells in culture. Evidence for an alpha chain derived from a larger biosynthetic precursor. (1982) (39)
- Effects of moisture and temperature on the osteoinductivity of demineralized bone matrix (2005) (39)
- The Cross‐Linking and Structure Modification of the Collagen Matrix in the Design of Cardiovascular Prosthesis (1988) (39)
- Penicillamine and collagen metabolism. (1979) (37)
- Effects of indomethacin on demineralized bone‐induced heterotopic ossification in the rat (1991) (37)
- Synthesis of aldehydes and their interactions during the in vitro aging of collagen. (1971) (37)
- Phenotypic differentiation of TGF-beta1-responsive pluripotent premesenchymal prehematopoietic progenitor (P4 stem) cells from murine bone marrow. (2001) (36)
- Effects of gamma irradiation on osteoinduction associated with demineralized bone matrix (2008) (36)
- Calcification of implanted vascular tissues associated with elastin in an experimental animal model. (1992) (36)
- Zinc as a possible preventive and therapeutic agent in pancreatic, prostate, and breast cancer (2016) (35)
- Alteration of collagen composition and cross-linking in keloid tissues. (1990) (34)
- A modified collagenase assay method based on the use of p-dioxane. (1979) (34)
- Collagen Defect Induced by Peniciflamine (1965) (33)
- Effects of lysosomal enzymes on the type of collagen synthesized by bovine articular cartilage. (1973) (32)
- Refolding of a recombinant collagen-targeted TGF-beta2 fusion protein expressed in Escherichia coli. (1997) (32)
- Combined Effects of Phosphatidylcholine and Demineralized Bone Matrix on Bone Induction (2003) (31)
- Modulation of endothelial cell morphology and collagen synthesis by polymorphonuclear leukocytes. (1983) (30)
- Turnover and age distribution of a collagen fraction extractable from rat skin by mercaptoethylamine. (1967) (29)
- Extraction of α and β components from insoluble collagen by thiol compounds (1966) (29)
- Chemical changes associated with aging of collagen in vivo and in vitro. (1969) (28)
- Design, expression, and renaturation of a lesion-targeted recombinant epidermal growth factor-von Willebrand factor fusion protein: efficacy in an animal model of experimental colitis. (2000) (28)
- Transdermal Delivery and Accumulation of Indomethacin in Subcutaneous Tissues in Rats (1998) (28)
- Biochemical differences between dystrophic calcification of cross-linked collagen implants and mineralization during bone induction (1988) (28)
- Type I collagen synthesis by corneal endothelial cells modulated by polymorphonuclear leukocytes. (1985) (26)
- The effect of various avocado oils on skin collagen metabolism. (1991) (25)
- Postmortem degradation of demineralized bone matrix osteoinductive potential. Effect of time and storage temperature. (1991) (25)
- Soluble collagen with high aldehyde content extracted from insoluble collagen with mercaptoethylamine. (1968) (24)
- Production of a recombinant human basic fibroblast growth factor with a collagen binding domain (2005) (24)
- Cultures of Ligament Fibroblasts in Fibrin Matrix Gel (2003) (24)
- A defect in the intramolecular and intermolecular cross-linking of collagen caused by penicillamine. 3. Accumulation of acid soluble collagen with a high hydroxylysine content in bone. (1973) (23)
- Molecular Structure and Functions of Collagen (2018) (23)
- Metabolic pathways and control mechanisms involved in the biosynthesis and turnover of collagen in normal and pathological connective tissues. (1973) (23)
- Changes in the Quantity and Nature of Collagen in Rabbit Skin as a Function of Age (1965) (23)
- The short-term therapeutic effect of recombinant human bone morphogenetic protein-2 on collagenase-induced lumbar facet joint osteoarthritis in rats. (2007) (23)
- Chemical composition and biophysical properties of porcine cardiovascular tissues. (1975) (22)
- A highly specific and quantitative method for determining type III/I collagen ratios in tissues. (1990) (22)
- Cellular responses to silicone and polyurethane prosthetic surfaces. (1993) (22)
- Ectopic bone formation is enhanced in senescent animals implanted with embryonic cells. (1988) (21)
- Non-Suitability of Levator Ani Method as an Index of Anabolic Effect of Steroids (1957) (21)
- Isolation and characterization of cyanogen bromide peptides from the collagen of bovine articular cartilage. (1973) (20)
- Acylated ascorbate stimulates collagen synthesis in cultured human foreskin fibroblasts at lower doses than does ascorbic acid. (1998) (20)
- Fibroblast contraction of collagen matrices with and without covalently bound hyaluronan. (1993) (19)
- Injectable gel graft for bone defect repair. (2014) (18)
- Stability of the collagen phenotype and decreased collagen production in serial subcultures of rabbit corneal endothelial cells. (1981) (18)
- Biochemistry and biomechanics (1988) (18)
- Transdermal Delivery of Amino Acids and Antioxidants Enhance Collagen Synthesis: In Vivo and In Vitro Studies (2005) (18)
- Crosslinked CNBr-activated hyaluronan-collagen matrices: effects on fibroblast contraction. (1994) (18)
- DEMINERALIZED BONE MATRIX/ POLYDIOXANONE COMPOSITE AS A SUBSTITUTE FOR BONE GRAFT: A COMPARATIVE STUDY IN RATS (1992) (17)
- Identification of stable intermolecular crosslinks present in reconstituted native collagen fibers. (1972) (17)
- Somatostatin can locally inhibit proliferation and differentiation of cartilage and bone precursor cells (2006) (16)
- Changes in the ratio of non-calcified collagen to calcified collagen in human vertebrae with advancing age. (1993) (16)
- Reversibility of a Penicillamine Induced Defect in Collagen Aggregation (1967) (16)
- Identification of a large interrupted helical domain of disulfide-bonded cartilage collagen. (1984) (16)
- Metabolic and anti-inflammatory properties of 6-methyl prednisolone alone and in combination with anabolic hormones. (1962) (15)
- Nitric oxide mediates hyperglycemia-induced defective migration in cultured endothelial cells. (1997) (15)
- In situ collagen gel mold as an aid in excimer laser superficial keratectomy. (1992) (15)
- Stability of collagen phenotype in morphologically modulated rabbit corneal endothelial cells. (1984) (15)
- Effects of non-steroidal anti-inflammatory drugs on demineralized bone-induced bone formation. (1992) (15)
- Ultrasound debridement of trabeculated bone: effective and atraumatic. (1994) (13)
- Type I collagen combined with a recombinant TGF-beta serves as a scaffold for mesenchymal stem cells. (1996) (13)
- Glutaraldehyde fixation revisited. (2001) (13)
- Vinblastine sulfate. Its reversible thermal aggregation and interaction with hydrophobic groups. (1972) (12)
- Dietary Composition and Tissue Protein Synthesis I. Effect of Tryptophan Deficiency.∗ (1961) (12)
- Effects of lathyritic drugs and lathyritic demineralized bone matrix on induced and sustained osteogenesis (1994) (12)
- Collagen in the Developing Larynx (1992) (11)
- Topical griseofulvin in tinea versicolor: a double-blind study. (1991) (11)
- Collagen in Cardiovascular Tissues (1992) (11)
- Effect of Testosterone Propionate on Tissue Protein Synthesis in the Castrated Male Rat.∗ (1961) (11)
- An efficient method for in vitro labeling proteins to high specific radioactivity using 3H-NaBH4 in dimethylformamide. (1981) (10)
- Whole Organ Evaluation of Collagen in the Developing Human Larynx and Adjoining Anatomic Structures (Hyoid and Trachea) (1993) (10)
- Inhibition of ectopic calcification of glutaraldehyde crosslinked collagen and collagenous tissues by a covalently bound diphosphonate (APD). (1990) (10)
- The biosynthesis of microsomal-bound collagen pn precursors in rabbit embryo skin in vitro. (1965) (10)
- Testosterone-induced N-retention in castrated rats on diets containing incomplete proteins. (1957) (10)
- Cells isolated from fetal rat calvaria by isopycnic separation express different collagen phenotypes. (1989) (9)
- An Ultrastructural Study of Retrocorneal Fibrous Membrane-Like Corneal Endothelial Metaplasia In vitro (1980) (9)
- Hyoepiglottic ligament collagen and elastin fiber composition and changes associated with aging (2018) (9)
- In vitro formation of intramolecular crosslinks in tropocollagen. (1969) (9)
- Effects of Hormone Administration on Collagen Biosynthesis in the Rat.∗ (1962) (8)
- Biochemistry of bone induction and dystrophic calcification. (1994) (8)
- Delivery of Erythromycin to Subcutaneous Tissues in Rats by Means of a Trans‐phase Delivery System (1999) (8)
- A modified rhTGF-beta1 and rhBMP-2 are effective in initiating a chondro-osseous differentiation pathway in bone marrow cells cultured in vitro. (2003) (8)
- The use of 2-dimensional CNBr peptide maps for the analysis of crosslinked peptides in bone collagen. (1981) (7)
- Session 1: Collagen Cross-Linking and Biomineralization (1992) (7)
- The role of fibronectin and substrate size in attachment of rat bone marrow cells to an osteoinductive matrix. (1981) (7)
- In vitro formation of crosslinks in mature rat skin collagen in the absence of N-terminal peptides. (1971) (7)
- A new technique for isolation of Descemet's membrane: preliminary studies. (1979) (6)
- Tissue distribution and excretion of alpha-aminoisobutyric acid in the rat. I. Effect of dietary protein level and composition. (1963) (5)
- SENSITIVE BIOLOGICAL TESTS FOR MEDICAL GRADE PLASTICS. I. TOXICITY OF ORGANO-TIN STABILIZERS. (1964) (5)
- Effects of High Fat and Carbohydrate Diets on Rat Liver Phosphatase.∗ (1957) (5)
- MACROPHAGES AND CARTILAGE DESTRUCTION (1976) (5)
- Calcification of osteoblastlike rat osteosarcoma cells in agarose suspension cultures (1987) (5)
- Localized gamma irradiation from cobalt-60 on synthesis of collagen by subcutaneous granulomas. (1965) (5)
- Flexibility of the chondrocyte collagen phenotype (1981) (5)
- EFFECT OF BIOFLAVONOIDS AND METHYLPREDNISOLONE ON COLLAGEN BIOSYNTHESIS. (1964) (5)
- Collagen and collagen-glycosaminoglycan matrices as carriers for growth factors (1999) (4)
- A new model for heterotopic aortic valve transplantation. (1997) (4)
- Collagen and Hexosamine Changes in Subcutaneous Granuloma Irradiated Locally with a Co60Source.∗ (1966) (4)
- Collagen: Volume I: Biochemistry (2017) (4)
- COLLAGEN OF RAT SKIN AND BOVINE ARTICULAR CARTILAGE: THEIR HYDRODYNAMIC PROPERTIES DURING INTERACTIONS WITH PROTEOGLYCANS (1975) (4)
- Influence of penicillamine and various analogs on matrix-induced bone formation in rats. (1984) (4)
- Acidosis and Formaldehyde Secretion as a Possible Pathway of Cancer Pain and Options for Improved Cancer Pain Control (2015) (4)
- Dietary composition and tissue protein synthesis. II. Tryptophan toxicity and amino acid deficiency in collagen synthesis. (1962) (3)
- Effect of monensin on secretion of basement membrane collagen by cultured rabbit corneal endothelial cells in comparison with rabbit tendon fibroblasts. (1984) (3)
- Chemical and mechanical changes in the collagenous framework of skin induced by thiol compounds. (1968) (3)
- Dietary adaptation and the level of glucose-6-phosphatase and phosphohexoseisomerase of rat liver. (1961) (3)
- V – THE MOLECULAR BIOLOGY OF COLLAGEN AND STRUCTURAL GLYCOPROTEINS (1972) (2)
- Collagen : Volume II: Biochemistry and Biomechanics (2018) (2)
- Collagen and Derived Peptides as Nutritional Supplements for Integumental Care (2018) (2)
- Effect of short-term feeding of fish oils and of antioxidants on plasma and liver cholesterol in the rat. (1961) (2)
- The collagen in normal ligaments. (1993) (2)
- Ligament shortening: an experimental approach (1994) (2)
- Effect of Dietary Composition on Rat Liver Phosphorylase Activity (1958) (2)
- The effects of heparin binding proteins in platelet releasate on bone formation. (2014) (2)
- TISSUE DISTRIBUTION OF ALPHA-AMINOISOBUTYRIC ACID AND NITROGEN METABOLISM IN THE RAT. II. EFFECTS OF ENVIRONMENTAL TEMPERATURE AND DIETARY IMBALANCE. (1964) (2)
- Chondroitin Sulfate and Sulfur Containing Chondroprotective Agents: Is there a Basis for their Pharmacological Action? (2006) (2)
- Demineralized Bone Matrix Osteoinductivity The Effect of Thrombin Activation of Platelet-Rich Plasma on (2009) (1)
- Ectopic calcification of glutaraldehyde crosslinked collagen bioprosthesis (1986) (1)
- Collagen derived matrices and related polypeptide growth factors: their potential for tissue repair and organ regeneration (1999) (1)
- Dystrophic calcification and mineralization during bone induction: biochemical differences. (1989) (1)
- Collagen: Biochemistry. Volume One. Biochemistry and Biomechanics. Volume Two. Biotechnology. Volume Three (1989) (1)
- Mechanisms of bone induction by decalcified bone matrix in rats of various ages (1986) (0)
- 50: FGF TOGETHER WITH COLLAGEN CARRIER FOR CALVARIAL DEFECT REPAIR (2011) (0)
- Fibula fracture healing with the composite of dimineralized bone matrix and silane modified gelatin (2009) (0)
- Collagen: Structure, Function and Biomaterial Properties (1986) (0)
- Modulation of collagen phenotype and cross linking in experimental systems (1984) (0)
- United States Patent ( 19 ) Nimni et al . 54 PROCESS FOR PURIFYING COLLAGEN AND GENERATING BOPROSTHESIS 76 Inventors : (2017) (0)
- Teaching nutrition for dental students University of Southern California. (1966) (0)
- Contents, Vol. 12, 1980 (1980) (0)
- Modulation of osteogenesis by isolated calvaria cells: a model for tissue interactions. (1990) (0)
- Topical griseofulvin in dermatophytoses. (2011) (0)
- Abstract 94: INJECTABLE GEL GRAFT FOR CRANIAL BONE DEFECT REPAIR (2013) (0)
- Mineralization of osteoblast-like suspensions of rat osteosarcoma cells in agarose (1986) (0)
- Dystrophic calcification and mineralization during bone induction: biochemical differences. (1989) (0)
- [Data on the anabolic activity of androgenic steroids]. (1958) (0)
- Reduction of fibroblast contraction on crosslinked hyaluronan-collagen matrices (1993) (0)
- Abstract 3833: A novel 3D remodelable hydrogel for bioengineering tumor . (2013) (0)
- Abstract 4064: 3D gel system to study tumor metastasis and EMT (2014) (0)
- Abstract 11: Cell-based Muscle Regeneration by utilizing Epigenetic Drug and Hydrogel (2015) (0)
- Homologous demineralised bone matrix (DBM) associated to autologous adipose mesenchymal stromal cells (aMSC) and efefcter cells (EC) against DBM induce bone tissue formation at two week post treatment of experimental jaw lesions in pigs (2014) (0)
- Enhanced mechanical properties of hydroxyapatite bone graft coated with silane modified gelatin (2009) (0)
- The Extracellular Matrix (1988) (0)
- Extraction of alpha and beta components from insoluble collagen by thiol compounds. (1966) (0)
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