Matityahu M. Fridkin
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Philosophy Biology
Matityahu M. Fridkin's Degrees
- Doctorate Medicine Stanford University
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(Suggest an Edit or Addition)Matityahu M. Fridkin's Published Works
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Published Works
- Bacterial induction of autoantibodies to beta2-glycoprotein-I accounts for the infectious etiology of antiphospholipid syndrome. (2002) (351)
- Enhancement of phagocytosis - a newly found activity of substance P residing in its N-terminal tetrapeptide sequence. (1980) (306)
- All‐D‐magainin: chirality, antimicrobial activity and proteolytic resistance (1990) (283)
- Growth factor function of vasoactive intestinal peptide in whole cultured mouse embryos (1993) (275)
- Antibodies against a synthetic peptide as a probe for the kinase activity of the avian EGF receptor and v-erbb protein (1985) (247)
- Historic perspective and recent developments on the insulin-like actions of vanadium; toward developing vanadium-based drugs for diabetes (2003) (199)
- Vasoactive Intestinal Peptide and Pituitary Adenylate Cyclase-activating Polypeptide Inhibit Tumor Necrosis Factor α Transcriptional Activation by Regulating Nuclear Factor-kB and cAMP Response Element-binding Protein/c-Jun* (1998) (192)
- Prevention of experimental antiphospholipid syndrome and endothelial cell activation by synthetic peptides. (1999) (179)
- Neuroprotective strategy for Alzheimer disease: intranasal administration of a fatty neuropeptide. (1996) (176)
- Regression of established murine carcinoma metastases following vaccination with tumour-associated antigen peptides (1995) (174)
- Vasoactive intestinal peptide prevents excitotoxic cell death in the murine developing brain. (1997) (174)
- CTL induction by a tumour-associated antigen octapeptide derived from a murine lung carcinoma (1997) (162)
- An antagonist to vasoactive intestinal peptide affects cellular functions in the central nervous system. (1991) (151)
- Insulin-like effects of vanadium: basic and clinical implications. (2000) (148)
- CTL induction by a tumour-associated antigen octapeptide derived from a murine lung carcinoma (1994) (145)
- Structure-function studies of polymyxin B nonapeptide: implications to sensitization of gram-negative bacteria. (2000) (140)
- Activity-dependent neurotrophic factor: structure-activity relationships of femtomolar-acting peptides. (1998) (127)
- A vasoactive intestinal peptide antagonist inhibits non-small cell lung cancer growth. (1993) (124)
- Gonadotropin-releasing hormone in milk. (1977) (122)
- Augmentation of the antibacterial activity of magainin by positive-charge chain extension (1992) (120)
- Severe microcephaly induced by blockade of vasoactive intestinal peptide function in the primitive neuroepithelium of the mouse. (1994) (119)
- The Binding Site of Acetylcholine Receptor as Visualized in the X-Ray Structure of a Complex between α-Bungarotoxin and a Mimotope Peptide (2001) (116)
- Enzymic degradation of luteinizing hormone-releasing hormone (LH-RH) by hypothalamic tissue. (1974) (113)
- NAP, a Femtomolar-Acting Peptide, Protects the Brain Against Ischemic Injury by Reducing Apoptotic Death (2002) (113)
- Adhesion of human platelets to serum amyloid A. (2002) (111)
- Analysis of ligand binding to the synthetic dodecapeptide 185-196 of the acetylcholine receptor alpha subunit. (1986) (110)
- Tuftsin: its chemistry, biology, and clinical potential. (1989) (108)
- Vasoactive intestinal peptide potentiates sexual behavior: Inhibition by novel antagonist (1989) (104)
- Tuftsin and some analogs: synthesis and interaction with human polymorphonuclear leukocytes. (1977) (102)
- A Synthesis of Cyclic Peptides Utilizing High Molecular Weight Carriers (1965) (102)
- Breast cancer growth is inhibited by vasoactive intestinal peptide (VIP) hybrid, a synthetic VIP receptor antagonist. (1996) (100)
- Superactive lipophilic peptides discriminate multiple vasoactive intestinal peptide receptors. (1995) (100)
- Production and characterization of an antiserum to synthetic gonadotropin-releasing hormone. (1973) (98)
- Serum amyloid A binds specific extracellular matrix glycoproteins and induces the adhesion of resting CD4+ T cells. (1996) (97)
- Tuftsin (an Ig-associated tetrapeptide) triggers the immunogenic function of macrophages: implications for activation of programmed cells. (1978) (90)
- IL-2 induces T cell adherence to extracellular matrix: inhibition of adherence and migration by IL-2 peptides generated by leukocyte elastase. (1998) (86)
- Coding sequences for vasoactive intestinal peptide and PHM-27 peptide are located on two adjacent exons in the human genome. (1985) (85)
- Resistance to enzymic degradation of LH-RH analogues possessing increased biological activity. (1977) (85)
- The functional association of polymyxin B with bacterial lipopolysaccharide is stereospecific: studies on polymyxin B nonapeptide. (2000) (78)
- Vasoactive intestinal peptide antagonist retards the development of neonatal behaviors in the rat (1991) (76)
- Extracellular matrix-anchored serum amyloid A preferentially induces mast cell adhesion. (1997) (74)
- Prolonging the Action of Protein and Peptide Drugs by a Novel Approach of Reversible Polyethylene Glycol Modification* (2004) (74)
- N-terminal modifications of Polymyxin B nonapeptide and their effect on antibacterial activity (2001) (73)
- Inhibition of cell adhesion to glycoproteins of the extracellular matrix by peptides corresponding to serum amyloid A. Toward understanding the physiological role of an enigmatic protein. (1994) (73)
- Luteinizing hormone-releasing hormone and thyrotropin-releasing hormone in human and bovine milk. (2005) (72)
- Structure-function studies of amphiphilic antibacterial peptides. (1993) (72)
- The efficacy of specific IVIG anti-idiotypic antibodies in antiphospholipid syndrome (APS): trophoblast invasiveness and APS animal model. (2007) (71)
- Suppression of gonadotropin secretion and prevention of ovulation in the rat by antiserum to synthetic gonadotropin-releasing hormone. (1973) (70)
- Antibodies to synthetic peptides as probes for the binding site on the alpha subunit of the acetylcholine receptor. (1985) (68)
- New useful reagents for peptide synthesis. Insoluble active esters of polystyrene-bound 1-hydroxybenzotriazole. (1975) (67)
- Activity of two synthetic amphiphilic peptides and magainin-2 against herpes simplex virus types 1 and 2. (2009) (67)
- Use of Polymers as Chemical Reagents. I. Preparation of Peptides (1966) (66)
- Modulation of the hydrophobic domain of polymyxin B nonapeptide: effect on outer-membrane permeabilization and lipopolysaccharide neutralization. (2002) (65)
- Degradation of gonadotropin-releasing hormones in the gilthead seabream, Sparus aurata. II. Cleavage of native salmon GnRH, mammalian LHRH, and their analogs in the pituitary, kidney, and liver. (1990) (63)
- Protection against developmental retardation in apolipoprotein E-deficient mice by a fatty neuropeptide: implications for early treatment of Alzheimer's disease. (1997) (63)
- Tryptophan residues of cholera toxin and its A and B protomers. Intrinsic fluorescence and solute quenching upon interacting with the ganglioside GM1, oligo-GM1, or dansylated oligo-GM1. (1981) (62)
- A VIP antagonist distinguishes VIP receptors on spinal cord cells and lymphocytes (1991) (62)
- VIP and peptides related to activity-dependent neurotrophic factor protect PC12 cells against oxidative stress (2000) (61)
- The gene for the neuropeptide gonadotropin-releasing hormone is expressed in the mammary gland of lactating rats. (1994) (60)
- The effect of Tuftsin on the nitrous blue tetrazolium reduction of normal human polymorphonuclear leukocytes. (1975) (60)
- Reversible PEGylation: a novel technology to release native interferon alpha2 over a prolonged time period. (2004) (60)
- Mapping the active site in vasoactive intestinal peptide to a core of four amino acids: neuroprotective drug design. (1999) (59)
- From vasoactive intestinal peptide (VIP) through activity-dependent neuroprotective protein (ADNP) to NAP (2007) (58)
- Use of polymers as chemical reagents. II. Synthesis of bradykinin. (1968) (58)
- A β-hairpin structure in a 13-mer peptide that binds α-bungarotoxin with high affinity and neutralizes its toxicity (2001) (57)
- Specific binding sites for the phagocytosis stimulating peptide tuftsin on human polymorphonuclear leukocytes and monocytes. (1978) (56)
- A peptide that shares similarity with bacterial antigens reverses thrombogenic properties of antiphospholipid antibodies in vivo. (2004) (56)
- Decreased tuftsin concentrations in patients who have undergone splenectomy. (1977) (56)
- High levels of vasoactive intestinal peptide in human milk. (1985) (56)
- Effect of serum amyloid A on selected in vitro functions of isolated human neutrophils. (1998) (55)
- Reversible PEGylation of peptide YY3‐36 prolongs its inhibition of food intake in mice (2005) (53)
- Peptides generated from C-reactive protein by a neutrophil membrane protease. Amino acid sequence and effects of peptides on neutrophil oxidative metabolism and chemotaxis. (1990) (52)
- Radioimmunoassay of the phagocytosis‐stimulating peptide tuftsin in normal and splenectomized subjects (1977) (51)
- Neuroprotection of the developing brain by systemic administration of vasoactive intestinal peptide derivatives. (1999) (51)
- Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 1. General introduction. (1976) (50)
- VIP-related protection against lodoacetate toxicity in pheochromocytoma (PC12) cells (2000) (49)
- Prolonging the half-life of human interferon-α2 in circulation: Design, preparation, and analysis of (2-sulfo-9-fluorenylmethoxycarbonyl)7- interferon-α2 (2001) (49)
- Stearyl-norleucine-vasoactive intestinal peptide (VIP): a novel VIP analog for noninvasive impotence treatment. (1994) (49)
- Degradation of gonadotropin-releasing hormones in the gilthead seabream, Sparus aurata. I. Cleavage of native salmon GnRH and mammalian LHRH in the pituitary. (1990) (47)
- Novel therapeutic compound tuftsin–phosphorylcholine attenuates collagen‐induced arthritis (2016) (46)
- Modulation of human neutrophil function by C-reactive protein. (1987) (46)
- Angiotensin 1-7 as Means to Prevent the Metabolic Syndrome (2013) (46)
- VIP receptor antagonists and chemotherapeutic drugs inhibit the growth of breast cancer cells (2001) (45)
- Design and synthesis of peptides that bind α-bungarotoxin with high affinity (2001) (43)
- Thiolysis of dinitrophenylimidazoles and its use during synthesis of histidine peptides. (1970) (43)
- Peptide analogs to pathogenic epitopes of the human acetylcholine receptor alpha subunit as potential modulators of myasthenia gravis. (1996) (42)
- Degradation of gonadotropin‐releasing hormone by anterior pituitary enzymes (1981) (42)
- 1-Aminocyclobutanecarboxylic acid derivatives as novel structural elements in bioactive peptides: application to tuftsin analogs. (1996) (42)
- Novel breast‐tumor‐associated MUC1‐derived peptides: Characterization in Db−/− × β2 microglobulin (β2m) null mice transgenic for a chimeric HLA‐A2.1/Db‐β2 microglobulin single chain (2000) (41)
- Vasoactive intestinal peptide: a growth promotor in neuroblastoma cells (1993) (40)
- Immunoreactive and biologically active somatostatin in human and sheep milk. (1985) (40)
- Comparative structure-activity studies on mammalian [Arg8] LH-RH and chicken [Gln8] LH-RH by fluorimetric titration. (1983) (39)
- Pharmacologically distinct vasoactive intestinal peptide binding sites: CNS localization and role in embryonic growth (1999) (38)
- Self and foreign 60-kilodalton heat shock protein T cell epitope peptides serve as immunogenic carriers for a T cell-independent sugar antigen. (1995) (38)
- Successful modulation of murine lupus nephritis with tuftsin-phosphorylcholine. (2015) (37)
- A peptide composed of tandem analogs of two myasthenogenic T cell epitopes interferes with specific autoimmune responses. (1997) (37)
- Characterization of novel breast carcinoma-associated BA46-derived peptides in HLA-A2.1/D(b)-beta2m transgenic mice. (2002) (37)
- Structure and expression of the vasoactive intestinal peptide (VIP) gene in a human tumor (1986) (37)
- L-Glutamic acid gamma-monohydroxamate. A potentiator of vanadium-evoked glucose metabolism in vitro and in vivo. (1999) (37)
- Structure-function studies of cholera toxin and its A and B protomers. Modification of tryptophan residues. (1981) (37)
- The Binding Site of Acetylcholine Receptor (2003) (36)
- Reversible pegylation of insulin facilitates its prolonged action in vivo. (2008) (36)
- A fatty neuropeptide. Potential drug for noninvasive impotence treatment in a rat model. (1992) (35)
- Phosphorylcholine-tuftsin compound prevents development of dextransulfate-sodium-salt induced murine colitis: implications for the treatment of human inflammatory bowel disease. (2015) (35)
- Albumin-insulin conjugate releasing insulin slowly under physiological conditions: a new concept for long-acting insulin. (2005) (34)
- VIP analogues inhibit small cell lung cancer growth (1992) (33)
- Structural features of luliberin (luteinising hormone-releasing factor) inferred from fluorescence measurements. (1976) (33)
- SYNTHESES AND POLYMERIZATION OF α-TRIMETHYLSILYL ACRYLIC MONOMERS (1963) (32)
- Organic vanadium chelators potentiate vanadium-evoked glucose metabolism in vitro and in vivo: establishing criteria for optimal chelators. (2000) (32)
- Localization of sequence-determined neoepitopes and neutrophil digestion fragments of C-reactive protein utilizing monoclonal antibodies and synthetic peptides. (1992) (32)
- Self heat-shock protein (hsp60) peptide serves in a conjugate vaccine against a lethal pneumococcal infection. (1999) (32)
- Binding of human serum amyloid P component (hSAP) to human neutrophils. (1994) (31)
- Identification of shared tumor-associated antigen peptides between two spontaneous lung carcinomas. (1997) (30)
- (Stearyl, Norleucine17)VIP hybrid antagonizes VIP receptors on non-small cell lung cancer cells. (1997) (30)
- Immune Response of SLE Patients to Peptides Based on the Complementarity Determining Regions of a Pathogenic Anti-DNA Monoclonal Antibody (2000) (30)
- Peptide synthesis by means of tert-butyloxycarbonylamino acid derivatives of poly(ethylene-co-N-hydroxymaleimide). (1972) (30)
- A novel approach for a water-soluble long-acting insulin prodrug: design, preparation, and analysis of [(2-sulfo)-9-fluorenylmethoxycarbonyl](3)-insulin. (2000) (29)
- Neopeptide Antibiotics That Function as Opsonins and Membrane-Permeabilizing Agents for Gram-Negative Bacteria (2005) (28)
- Pneumococcal Capsular Polysaccharide Is Immunogenic When Present on the Surface of Macrophages and Dendritic Cells: TLR4 Signaling Induced by a Conjugate Vaccine or by Lipopolysaccharide Is Conducive1 (2008) (28)
- Turning low-molecular-weight drugs into prolonged acting prodrugs by reversible pegylation: a study with gentamicin. (2008) (28)
- Synthesis and biological activity of tuftsin and of [O = C Thr1]-tuftsin. A novel synthetic route to peptides containing N-terminal L -O = C Thr and L - O = C Ser residues. (2009) (28)
- Studies on the enzymic degradation of luteinizing hormone releasing hormone by rat pituitary plasma membranes. (1981) (28)
- On the Synthesis of Naphthoquinonyl Heterocyclic Amino Acids (1996) (27)
- Characterizing immunodominant and protective influenza hemagglutinin epitopes by functional activity and relative binding to major histocompatibility complex class II sites (1997) (27)
- New concept for long-acting insulin: spontaneous conversion of an inactive modified insulin to the active hormone in circulation: 9-fluorenylmethoxycarbonyl derivative of insulin. (1999) (27)
- Decreased serum tuftsin concentrations in sickle cell disease. (1980) (26)
- Toxicology and Antitumor Activity of Tuftsin a (1983) (26)
- Tuftsin‐AZT conjugate: potential macrophage targeting for AIDS therapy (2005) (26)
- Design and synthesis of peptides that bind alpha-bungarotoxin with high affinity and mimic the three-dimensional structure of the binding-site of acetylcholine receptor. (2002) (25)
- Growth hormone releasing factor-like immunoreactivity in human milk. (1986) (24)
- Anti-acetylcholine receptor response achieved by immunization with a synthetic peptide from the receptor sequence. (1984) (24)
- Peptides related to the calcium binding domains II and III of calmodulin. Synthesis and calmodulin-like features. (2009) (24)
- Detection of mRNAs containing regulatory peptide coding sequences using synthetic oligodeoxynucleotides (1984) (24)
- New Technologies to Prolong Life-time of Peptide and Protein Drugs In vivo (2007) (24)
- Vanadate restores glucose 6-phosphate in diabetic rats: a mechanism to enhance glucose metabolism. (2000) (24)
- Spectral studies with histidyl-tryptophan peptides. (1969) (23)
- Estrogen regulation of vasoactive intestinal peptide mRNA in rat hypothalamus (2008) (23)
- Vasoactive intestinal peptide: a growth promoter in neuroblastoma cells. (1993) (23)
- Tuftsin-Phosphorylcholine Maintains Normal Gut Microbiota in Collagen Induced Arthritic Mice (2017) (23)
- Antibodies directed against phosphothreonine residues as potent tools for studying protein phosphorylation. (1989) (23)
- Combined Local Blood–Brain Barrier Opening and Systemic Methotrexate for the Treatment of Brain Tumors (2015) (23)
- β2-Glycoprotein-I based peptide regulate endothelial-cells tissue-factor expression via negative regulation of pGSK3β expression and reduces experimental-antiphospholipid-syndrome. (2011) (22)
- The molecular and cellular basis of exostosis formation in hereditary multiple exostoses (2008) (22)
- An immunoreceptor tyrosine-based inhibitory motif, with serine at site Y-2, binds SH2-domain-containing phosphatases. (2000) (22)
- Receptor-mediated endocytosis of tuftsin by macrophage cells. (1984) (22)
- (N-stearyl, norleucine17) VIP hybrid inhibits the growth of pancreatic cancer cell lines. (1999) (22)
- Reversible pegylation prolongs the hypotensive effect of atrial natriuretic peptide. (2008) (21)
- Neuropeptides and Neuronal Survival: Neuroprotective Strategy for Alzheimer's Disease a (1997) (21)
- The substrate-binding domain of 21-hydroxylase, the main autoantigen in autoimmune Addison's disease, is an immunodominant T cell epitope. (2006) (21)
- Single amino acid analogs of a myasthenogenic peptide modulate specific T cell responses and prevent the induction of experimental autoimmune myasthenia gravis (1998) (21)
- Archaebacterial and eukaryotic proteasomes prefer different sites in cleaving gonadotropin-releasing hormone (1995) (21)
- Novel glycosylated VIP analogs: synthesis, biological activity, and metabolic stability (2008) (20)
- Monofunctional substrates of polynucleotide phosphorylase. The monoaddition of 2'(3')-O-isovaleryl-nucleoside diphosphate to an initiator oligonucleotide. (1971) (20)
- Deoxyoligonucleotide synthesis using a new phosphate protecting group. (1973) (20)
- Tuftsin, Thr-Lys-Pro-Arg (1981) (20)
- Peptide Derived from HIV-1 TAT Protein Destabilizes a Monolayer of Endothelial Cells in an in Vitro Model of the Blood-Brain Barrier and Allows Permeation of High Molecular Weight Proteins* (2012) (20)
- Effect of serum amyloid A, HDL-apolipoprotein, on endothelial cell proliferation. Implication of an enigmatic protein to atherosclerosis. (1996) (19)
- Hypothalamic hormones in milk. (1991) (19)
- Tuftsin analogs for probing its specific receptor site on phagocytic cells. (1982) (19)
- Studies toward the biosynthesis of vasoactive intestinal peptide (VIP) (1984) (19)
- Inhibition of human neuroblastoma growth by a specific VIP antagonist (2007) (18)
- Prolonging the half-life of human interferon-alpha 2 in circulation: Design, preparation, and analysis of (2-sulfo-9-fluorenylmethoxycarbonyl)7- interferon-alpha 2. (2001) (18)
- PACAP hybrid: a new PACAP receptor antagonist. (1997) (18)
- A VIP hybrid antagonist: From developmental neurobiology to clinical applications (1995) (17)
- C-reactive protein (CRP) peptides inactivate enolase in human neutrophils leading to depletion of intracellular ATP and inhibition of superoxide generation. (1992) (17)
- Novel breast-tumor-associated MUC1-derived peptides: characterization in Db-/- x beta2 microglobulin (beta2m) null mice transgenic for a chimeric HLA-A2.1/Db-beta2 microglobulin single chain. (2000) (17)
- A new route to polyamino acids containing histidine. (1971) (17)
- Altered Peptide Ligands of a Myasthenogenic Epitope as Modulators of Specific T‐Cell Responses (1996) (17)
- The use of polymeric carriers in the synthesis of cyclic peptides containing s s bonds abstract (1968) (16)
- Mapping of the cAMP‐dependent phosphorylation sites on the acetylcholine receptor. (1986) (16)
- Structure-activity relationships of luliberin substituted at position 8. (1976) (16)
- Design and synthesis of peptides that bind alpha-bungarotoxin with high affinity. (2001) (16)
- Synthesis and biological activity of tuftsin and rigin derivatives containing monosaccharides or monosaccharide derivatives. (1987) (16)
- Novel naphthoquinonyl derivatives: Potential structural components for the synthesis of cytotoxic peptides (1996) (16)
- A peptide based on the CDR3 of an anti-DNA antibody of experimental SLE origin is also a dominant T-cell epitope in (NZBXNZW)F1 lupus-prone mice. (2000) (16)
- Helminth-Based Product and the Microbiome of Mice with Lupus (2019) (16)
- Structure activity relationship study of polymyxin B nonapeptide. (2000) (15)
- Neuropeptide receptor transcripts are expressed in the rat clitoris and oscillate during the estrus cycle in the rat vagina (2005) (15)
- Delivery of neuropeptides from the periphery to the brain: studies with enkephalin. (2010) (15)
- Binding of human serum amyloid A (hSAA) and its high-density lipoprotein3 complex (hSAA-HDL3) to human neutrophils. Possible implication to the function of a protein of an unknown physiological role. (2009) (15)
- Engineering prolonged-acting prodrugs employing an albumin-binding probe that undergoes slow hydrolysis at physiological conditions. (2010) (15)
- A photolabile protecting group for the phenolic hydroxyl function of tyrosine. (2009) (14)
- Use of Nim-t-Butyloxycarbonyl in the Synthesis of Poly-L-histidine (1971) (14)
- Immunogenicity of H-2Kb-low affinity, high affinity, and covalently-bound peptides in anti-tumor vaccination. (1999) (14)
- Generation and use of antibodies to phosphothreonine. (1991) (14)
- N-[(2-Sulfo)-9-fluorenylmethoxycarbonyl](3)-gentamicin C(1) is a long-acting prodrug derivative. (2002) (14)
- A vasoactive intestinal peptide receptor analog alters the expression of homeobox genes. (2002) (14)
- Thiolysis of O-2,4-dinitrophenyltyrosines. Spectrophotometric monitoring of the reaction and its use in peptide synthesis. (1977) (14)
- Generation of specific antiserum to thyrotropin releasing‐hormone and its use in a radioimmunoassay (1976) (14)
- Poly(L‐leucyl‐L‐ornithyl‐L‐leucine) and its Guanidization Product: Synthesis and Antibacterial Activity (1969) (14)
- Characterization of neutrophil‐mediated degradation of human C‐reactive protein and identification of the protease (1992) (13)
- Tuftsin and tuftsin conjugates potentiate immunogenic processes: effects and possible mechanisms. (1987) (13)
- The binding site of acetylcholine receptor: from synthetic peptides to solution and crystal structure. (2003) (13)
- Acquired Tuftsin Deficiency (1983) (13)
- A new approach for prolonging the half-life of peptides, proteins and low-molecular-weight drugs in vivo (2001) (12)
- Tuftsin–phosphorylcholine (TPC) equally effective to methylprednisolone in ameliorating lupus nephritis in a mice model (2018) (12)
- Poly(L‐histidyl‐L‐alanyl‐α‐L‐glutamic acid). II. Catalysis of p‐nitrophenyl acetate hydrolysis (1978) (12)
- Facile thiolytic removal of the o-nitrophenylsulphenyl amino-protecting group. (2009) (12)
- Modulation of prostaglandin I2 production from bovine aortic endothelial cells by serum amyloid A and its N-terminal tetradecapeptide. (1996) (12)
- The 2,4-dinitrophenyl group for protection of hydroxyl function of tyrosine during solid-phase peptide synthesis. (2009) (12)
- Functionalization of polystyrene. III. Synthesis of polymeric thiol reagents (1982) (12)
- Sequential degradation of the neuropeptide gonadotropin‐releasing hormone by the 20 S granulosa cell proteasomes (1994) (12)
- Design, synthesis, and evaluation of a long-acting, potent analogue of gonadotropin-releasing hormone. (2001) (12)
- Structure-function relationship in the interaction of mastoparan analogs with neutrophil NADPH oxidase. (2001) (12)
- Helminths-based bi-functional molecule, tuftsin-phosphorylcholine (TPC), ameliorates an established murine arthritis (2018) (12)
- Synthesis of poly‐L‐asparagine and poly‐L‐glutamine (1969) (11)
- Glyco-tuftsin derivatives modulate interleukin-1 and tumor necrosis factor production. (2009) (11)
- Inhibition by tuftsin of Rauscher virus leukemia development in mice. (1983) (11)
- A Fatty Neuropeptide: Potential Drug for Noninvasive Impotence Treatment in a Rat Model (1993) (11)
- Tuftsin analogues: synthesis, structure-function relationships, and implications for specificity of tuftsin's bioactivity. (1986) (11)
- Nonaqueous titrimetric determination of active esters of amino acids and peptide derivatives. (1970) (11)
- Thiolysis of the 3-nitro-2-pyridinesulfenyl (Npys) protecting group. An approach towards a general deprotection scheme in peptide synthesis. (1990) (10)
- Protection Against Developmental Deficiencies by a Lipophilic VIP Analogue (1998) (10)
- ‘1-8 interferon inducible gene family’: putative colon carcinoma-associated antigens (2007) (10)
- Use of trityl- and -naphthylcarbamoylcellulose derivatives in oligonucleotide synthesis. (1973) (10)
- Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 11. Enzymatic joining to form the total DNA duplex. (1976) (10)
- Synthesis of modified tuftsins containing monosaccharides or monosaccharide derivatives. (1987) (10)
- Design and synthesis of potent hexapeptide and heptapeptide gonadotropin-releasing hormone antagonists by truncation of a decapeptide analogue sequence. (2000) (10)
- Peptides derived from human C-reactive protein inhibit the enzymatic activities of human leukocyte elastase and cathepsin G: use of overlapping peptide sequences to identify a unique inhibitor. (2009) (9)
- On the function of arginine in luteinizing hormone‐releasing hormone (1977) (9)
- Peptide fragments from the tuftsin containing domain of immunoglobulin G synthesis and biological activity. (1983) (9)
- Synthesis and catalytic properties of the heptapeptide L-seryl-L-prolyl-L-cysteinyl-L-steryl-alpha-L-glutamyl-L-threonyl-L-tyrosine. (1974) (9)
- Tuftsin induces tissue factor-like activity in human mononuclear cells and in monocytic cell lines. (1990) (9)
- Insulin-like Effects of Vanadium; Reviewing In Vivo and In Vitro Studies and Mechanisms of Action (1998) (8)
- Use of Polymeric Reagents in the Synthesis of Linear and Cyclic Peptides (1973) (8)
- Toxicology and antitumor activity of tuftsin in mice. Abstr. (1981) (8)
- Newly designed modifier prolongs the action of short-lived peptides and proteins by allowing their binding to serum albumin. (2012) (8)
- Synthesis and bioactivity of fatty acid-conjugated GnRH derivatives. (1999) (8)
- [2-Sulfo-9-fluorenylmethoxycarbonyl]3-exendin-4-a long-acting glucose-lowering prodrug. (2003) (8)
- Suspensions of pro-drug insulin greatly prolong normoglycemic patterns in diabetic rats. (2003) (8)
- Serum amyloid A complexed with extracellular matrix induces the secretion of tumor necrosis factor-α by human T-lymphocytes (1998) (8)
- Novel extended and branched N-terminal analogs of VIP (2006) (7)
- Degradation of Luteinizing Hormone-Releasing Hormone by Rat Pituitary Plasma Membrane Associated Enzymes (1984) (7)
- Structure-activity studies of reduced-size gonadotropin-releasing hormone agonists derived from the sequence of an endothelin antagonist. (2000) (7)
- Polymeric 2-mercaptopyridine and 2-mercapto-nitrobenzene derivatives. New reagents for peptide synthesis. (2009) (7)
- Growth hormone releasing factor and somatostatin concentrations in the milk of lactating women (1988) (7)
- NMR studies of H-D exchange of α-CH group of amino acid residues in peptides (1970) (7)
- ANTINEOPLASTIC, IMMUNOGENIC AND OTHER EFFECTS OF THE TETRAPEPTIDE TUFTSIN: A NATURAL MACROPHAGE ACTIVATOR (1983) (6)
- Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 5. Synthesis of the deoxyribopolynucleotide segments representing the nucleotide sequence 71-103. (1976) (6)
- The short-lived exostosis induced surgically versus the lasting genetic hereditary multiple exostoses. (2003) (6)
- Development of VIP Agonists and Antagonists with Tissue and Receptor Specificity: Effects on Behavioral Maturation, Sexual Function, and the Biologic Clock a (1996) (6)
- Mast cell adhesion to extracellular matrix: local effects of acute phase reactants. (1997) (6)
- Polytuftsin: a potential precursor for slow release of the phagocytosis stimulating peptide tuftsin. (1990) (6)
- Purification of the gonadotropin-releasing hormone-degrading enzyme by affinity chromatography. (1977) (6)
- INFLUENCE OF THE SYNTHETIC PENTAPEPTIDE LAsp‐Ser‐Asp‐Pro‐Arg ON THE DIRECT AND INDIRECT MAST CELL DEGRANULATION INDUCED BY REAGINIC ANTIBODIES (1977) (6)
- Synthetic peptides derived from the sequence of human C-reactive protein inhibit the enzymatic activities of human leukocyte elastase and human leukocyte cathepsin G. (2009) (6)
- The therapeutic potential of tuftsin-phosphorylcholine in giant cell arteritis. (2019) (5)
- The infectious origin of the antiphospholipid syndrome: induction by passive transfer of anti- β2GPI Abs induced by common bacteria (2001) (5)
- Annals of the New York Academy of Sciences. Volume 419. Antineoplastic, Immunogenic and Other Effects of the Tetrapeptide Tuftsin: A Natural Macrophage Activator Held at New York on 16-17 February 1983, (1983) (5)
- Novel analogs of VIP with multiple C-terminal domains (2007) (5)
- Therapeutic Potential of Vasoactive Intestinal Peptide and its Derivative Stearyl-Norleucine-VIP in Inflammation-Induced Osteolysis (2021) (5)
- Localization of growth hormone-releasing hormone in the human hypothalamus and pituitary stalk. (1986) (5)
- Human peritoneal macrophage activity is increased by tuftsin. (1989) (5)
- Design and Synthesis of Peptides That Bind α-Bungarotoxin with High Affinity and Mimic the Three-Dimensional Structure of the Binding Site of Acetylcholine Receptor (2003) (5)
- Synthetic Pathways to Tuftsin and Radioimmunoassay (1983) (5)
- A peptide based on the sequence of the CDR3 of a murine anti-DNA mAb is a better modulator of experimental SLE than its single amino acid-substituted analogs. (2000) (5)
- A peptide based on the CDR1 of a pathogenic anti-DNA antibody is more efficient than its analogs in inhibiting autoreactive T cells. (2000) (5)
- Hexapeptide and cyclic pentapeptide endothelin antagonists directly activate pituitary gonadotropin-releasing hormone receptors. (2000) (4)
- Introduction of the dansyl group into histidine and tyrosine residues in peptides and proteins. (1985) (4)
- Poly(L‐histidyl‐L‐alanyl‐α‐L‐glutamic acid). I. Synthesis (1977) (4)
- PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE (PACAP)/VASOACTIVE INTESTINAL PEPTIDE (VIP) RECEPTOR SUBTYPES IN RAT TISSUES: INVESTIGATION OF RECEPTOR BINDING, A NOVEL VIP RECEPTOR ANTAGONIST AND CHEMICAL CROSS-LINKING (1994) (4)
- Antigen-tuftsin conjugate signals interleukin-1 synthesis and secretion. (1988) (4)
- Converting bleomycin into a prodrug that undergoes spontaneous reactivation under physiological conditions. (2019) (4)
- Detection of peptide active esters by thin-layer chromatography. (1970) (4)
- Tuftsin stimulates IL-1 production by human mononuclear cells, human spleen cells and mouse spleen cells in vitro. (1989) (4)
- The hydrolysis of p-nitrophenylacetate in water. Mechanism and method of measurement. (1974) (3)
- Estrogen regulation of vasoactive intestinal peptide mRNA in rat hypothalamus (2008) (3)
- Intranasal Delivery of Bioactive Peptides or Peptide Analogues Enhances Spatial Memory and Protects Against Cholinergic Deficits (2001) (3)
- Mediators of Cellular Immunity (1979) (3)
- Conformational changes of poly(L‐histidyl‐L‐alanyl‐α‐L‐glutamic acid) in solution. Transition pathways and conformational intermediates (1979) (3)
- Polymyxin B and Related Cyclic Peptides Facilitate Leanness and Reduce Fat Mass and Triglyceride Content in Ageing Rats: Potential Prototype Drugs Against Obesity (2006) (3)
- Retracted Correction: CTL induction by a tumour-associated antigen octapeptide derived from a murine lung carcinoma (1998) (3)
- Potential use of tuftsin in treatment of candida peritonitis in a murine model. (1989) (3)
- Synthesis, biological activity and resistance to enzymic degradation of luteinizing hormone—releasing hormone analogues modified at position 7 (1981) (3)
- A study of extracellular matrix-cell adhesion peptidic epitopes related to human serum amyloid A (SAA) (1999) (2)
- Synthetic peptide approach to the analysis of kinase activities of avian EGF receptor and v-erbB protein. (1985) (2)
- Studies on the activity of phorbol myrystate acetate on the human polymorphonuclear leukocytes (1979) (2)
- Detection of aromatic amino acid derivatives on thin-layer chromatograms by various electron acceptors. (1968) (2)
- The detection of peptide hydrazides on thin-layer chromatograms. (1970) (2)
- Tuftsin Receptors a (1983) (2)
- FACILE THIOLYTIC REMOVAL OF THE O-NITROPHENYLSULFENYL AMINO-PROTECTING GROUP (1979) (2)
- Thiolysis of Nim-2,4-dinitrophenyl-histidine peptides with 2-mercaptoethanol. An explannation for the pH optimum. (2009) (2)
- Synthesis and biological activity of [L‐hydroxyproline]3‐tuftsin analogue and its α‐ or β‐O‐D‐glucosylated derivatives (2009) (2)
- Protection against developmental and learning impairments in apolipoprotein e-deficient mice by activity-dependent femtomolar-acting peptides (1997) (2)
- SYNTHESIS OF STABLE SPIROOXYPHOSPHORANES : POTENTIAL PROMOTERS OF CATALYTIC ANTIBODIES (1996) (2)
- On the role of tryptophan in luteinizing-hormone-releasing hormone (luliberin). (1977) (2)
- Conjugation of Methotrexate-Amino Derivatives to Macromolecules through Carboxylate Moieties Is Superior Over Conventional Linkage to Amino Residues: Chemical, Cell-Free and In Vitro Characterizations (2016) (2)
- Immunostimulation by an Ig derived tetrapeptide, tuftsin (1979) (1)
- Degradation of C-reactive protein (CRP) by neutrophil lysosomal enzymes generates peptidic neutrophil modulators (1991) (1)
- Potentiating vanadium-evoked glucose metabolism by novel hydroxamate derivatives (2002) (1)
- The infectious origin of the antiphospholipid syndrome: induction by passive transfer of anti-β2GPI antibodies induced by common bacteria (2003) (1)
- Toward mechanized peptide synthesis via polymeric reagents approach (1977) (1)
- (4-Hydroxy-3-nitro)benzylated polystyrene. An improved polymeric nitrophenol derivative for peptide synthesis. (1974) (1)
- Establishing the principle of reversibility in peptide/protein and small-molecule therapy. (2012) (1)
- Blockade of VIP function in early mouse embryo induces severe microcephaly (1994) (1)
- Enzymatic processing of serum proteins: A route to peptides associated with host defense (1993) (1)
- Lipophilic vasoactive intestinal peptide: Potential drug for non-invasive impotence treatment (1993) (1)
- Abstracts of the 15th Annual Meeting of the Israel Society for Neuroscience Eilat, Israel, December 3–5, 2006 (2006) (1)
- Tumor-Associated Antigen Peptides as Anti-Metastatic Vaccines (2004) (1)
- Tuftsin-THF-gamma 2 chimeric peptides: potential novel immunomodulators. (1997) (1)
- Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 4. Synthesis of deoxyribopolynucleotide segments corresponding to the nucleotide sequence 47-78. (1976) (1)
- Proteolysis of human C-reactive protein by neutrophil-derived lysosomal enzymes generates peptides which modulate neutrophil function: Implication to the anti-inflammatory mechanism (1995) (1)
- NMR studies of H-D exchange of alpha-CH group of amino acid residues in peptides. (1970) (1)
- Preventive Treatment of Alzheimer’s Disease (1998) (1)
- Mercuration of tryptophan in luteinizing hormone-releasing hormone. (1978) (1)
- l-Glutamic Acid γ-Monohydroxamate (1999) (1)
- Pharmaceutical VIP: Prospects and Problems (1999) (1)
- VIP, novel proteins and peptide-mediated neuronal survival (2002) (0)
- Tuftsin Analogues: Synthesis, Structure-Function Relationships, and Im- plications for Specificity of Tuftsin′s Bioactivity. (1987) (0)
- Synthesis of Naphthoquinonyl Heterocylic Amino Acids. (1997) (0)
- Human serum amyloid P component (hSAP): Binding to and degradation by human polymorphonuclear leukocytes (1994) (0)
- P277 peptide analogs and pharmaceutical compositions comprising them for the treatment or diagnosis of diabetes. (1995) (0)
- Vip-related peptides for treatment of sexual dysfunction in women (2001) (0)
- Peptide synthesis. (1974) (0)
- Luliberin analogues exhibiting a cytotoxic effect on tumor cells in vitro (2006) (0)
- Poly(L-histidyl-L-alanyl-alpha-L-glutamic acid). I. Synthesis. (1977) (0)
- 3. The binding site for -bungarotoxin in the acetylcholine receptor: from synthetic peptides to solution and crystal structure (2003) (0)
- medicinal materials and Long-acting drug containing them (1997) (0)
- STRUCTURE ACTIVITY RELATIONSHIP STUDY OF POLYMYXIN B NONAPEPTIDE 1 (0)
- Serum Amyloid A Complexed with Extracellular Matrix Induces the Secretion of Tumor Necrosis Factor-α by human T-lymphocytes (2004) (0)
- SLE and other connective tissue diseases (animal models) (PP-017) (2010) (0)
- Abraham Patchornik — a scientist, a teacher, a friend (1994) (0)
- Development of Improved GNH Analogs for Controlled Reproduction of Sparus aurata in Farming Conditions (1985) (0)
- Gene therapy and peptide therapy of tumor metastasis (2007) (0)
- Modified VIP derivatives and pharmaceutical compositions containing them (1992) (0)
- Leukocyte Elastase and Migration by IL-2 Peptides Generated by Adherence Extracellular Matrix: Inhibition of IL-2 Induces T Cell Adherence to (1998) (0)
- Human and Murine β-Defensin-Derived Peptides Induce Rapid Mobilization Of Murine Hematopoietic Stem and Progenitor Cells Via Activation Of CXCR4 Signaling and CXCL12 Release (2013) (0)
- Inhibition of human leukocyte elastase and cathepsin G by extended peptides and subunits derived from human C-reactive protein (2004) (0)
- Organic polymeric reagents and methods for their preparation (1974) (0)
- Polymeric reagent synthesis of luteinizing hormone-releasing hormone (1977) (0)
- A study of extracellular matrix-cell adhesion peptidic epitopes related to human serum amyloid A (SAA) (2004) (0)
- Rapid separation of synthetic oligonucleotide mixtures on aromatic cellulose derivatives. (1974) (0)
- VIP, novel proteins and neuronal survival (2001) (0)
- 317 Immobilized serum amyloid A (SAA) induces mast cell (MC) adhesion to extracellular matrix (ECM) (1996) (0)
- Identification of Ser 153 in ICL2 of the GnRH receptor as a phosphorylation–independent site for inhibition of Gq coupling (2005) (0)
- Helminthes Derivative for Treating Acute and Chronic Colitis in Mice Models (2017) (0)
- New derivative of vasoacitive intestinal peptide (1992) (0)
- POLYMERIC 2-MERCAPTOPYRIDINE AND 2-MERCAPTO-NITROBENZENE DERIVATIVES. NEW REAGENTS FOR PEPTIDE SYNTHESIS (1981) (0)
- This information is current as by Lipopolysaccharide Is Conducive Signaling Induced by a Conjugate Vaccine or Macrophages and Dendritic Cells : TLR 4 ofImmunogenic When Present on the Surface Pneumococcal Capsular Polysaccharide Is Eisenbach (2008) (0)
- The Design, Synthesis, and Biological Evaluation of VIP and VIP Analogs (2008) (0)
- Polymeric organic reagents, particularly for organic syntheses, for the separation of metals, for ion-exchange and for scavenging aldehydes, and processes for their preparation (1975) (0)
- Actives prolonged effect and pharmaceutical composciones including them. (1997) (0)
- Peptides related to serum amyloid A (SAA) mediated cell adhesion: Implication to the physiological function of SAA (1993) (0)
- Structure and expression of the vasoactive intestinal peptide (VIP) gene (1985) (0)
- Cell Function-Associated Antigen Mediator of the Inhibitory Action of the Mast-Phosphatase Is the Main ′ Polyphosphate 5 SH 2 Domain-Containing Inositol (2001) (0)
- Potentiating vanadium-evoked glucose metabolism by novel hydroxamate derivatives (2004) (0)
- Modelins: A family of antibacterial computer-designed peptides (1993) (0)
- Highly active VIP - antagonists (1995) (0)
- Proteolysis of acute phase proteins: Implication to the anti-inflammatory response (1992) (0)
- Mechanisms controlling differentiation and function of antigen-presenting macrophages. (1982) (0)
- Novel magainin analogues: Structure-activity relationship (1991) (0)
- Biological activities of Polymyxin B nonapeptide analogs (2002) (0)
- A possible regulatory relationship exists between tuftsin and C-reactive protein (1993) (0)
- p277 PEPTIDE ANALOG, PHARMACEUTICAL COMPOSITION THEREOF FOR THE TREATMENT AND DIAGNOSIS OF DIABETES (1995) (0)
- VIP: Design and synthesis of novel analogs and elucidating potential mechanisms affecting sexual function (2006) (0)
- Acceleration of apoptotic cells clearance by macrophages upon exposure to serum amyloid P component and its synthetic derivates (2005) (0)
- RECEPTORS FOR TUFTSIN ON PLASMA MEMBRANES OF MACROPHAGES AND MACROPHAGE HYBRIDOMA CELL LINES (1987) (0)
- In vitro antiviral activity of two synthetic amphiphilic peptides and magainin-2 against herpes simplex virus types 1 and 2 (1993) (0)
- Hybrid peptides for the treatment of Bacteremia and sepsis (2002) (0)
- Peptides, used as a carrier in immunogenic constructs which are useful in the development of synthetic vaccines (1995) (0)
- Interferon and interleukin-derivatives with long-term effect, and compositions containing them, pharmaceutical (2001) (0)
- Long-acting medicaments and pharmaceutical compositions comprising these (1997) (0)
- POLYMERIC REAGENTS IN PEPTIDE SYNTHESIS (75 LITERATURANGABEN) (1981) (0)
- Binding pockets on the surface of human leukocyte elastase and human leukocyte cathepsin G. Implications to the design of inhibitors derived from human C-reactive protein. (1996) (0)
- Medicaments a absorption orale (2002) (0)
- Neuropeptides and skin cell function: VIP and stearyl-[Nle17]VIP effects on HaCaT cells (2002) (0)
- INVOLVEMENT OF TRYPTOPHAN IN THE BINDING SITE OF THE B PROTOMER OF CHOLERA TOXIN (1981) (0)
- ANTIBODIES TO SYNTHETIC PEPTIDES AS PROBES FOR THE a-SUBUNIT AND FOR THE CHOLINERGIC BINDING SITE OF THE ACETYLCHOLINE RECEPTOR (1985) (0)
- Tumor-associated antigen peptides as anti-metastatic vaccines (1998) (0)
- mechanism to enhance glucose metabolism Vanadate restores glucose 6-phosphate in diabetic rats: a (2016) (0)
- Authors' Reply (2009) (0)
- Synthesis and biological activity of [L-hydroxyproline]3-tuftsin analogue and its alpha- or beta-O-D-glucosylated derivatives. (1993) (0)
- P277 peptide analogs and pharmaceutical compositions containing them for the treatment of diabetes and diagnosis (1997) (0)
- Volumetric determination of amino acid and peptide hydrazides (1970) (0)
- Effect of O-Glycosylation on the Bioactivity of Tuftsin, (1992) (0)
- 36 Gene and peptide therapy of tumor metastases in murine models (1995) (0)
- VIP conjugates and their active fragments having hydrophobic moieties and topical Zuberetungen for use in the treatment of male impotence. (1989) (0)
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