Melvin I. Simon
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Chemistry Biology
Melvin I. Simon's Degrees
- Bachelors Chemistry California Institute of Technology
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(Suggest an Edit or Addition)Melvin I. Simon's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Cloning and stable maintenance of 300-kilobase-pair fragments of human DNA in Escherichia coli using an F-factor-based vector. (1992) (1633)
- The DNA sequence of human chromosome 22 (1999) (1117)
- Robust perfect adaptation in bacterial chemotaxis through integral feedback control. (2000) (1033)
- Flagellar rotation and the mechanism of bacterial motility (1974) (686)
- Macromolecular Crystallography: Part A (1997) (664)
- A Diverse Family of GPCRs Expressed in Specific Subsets of Nociceptive Sensory Neurons (2001) (597)
- The genome of Nanoarchaeum equitans: Insights into early archaeal evolution and derived parasitism (2003) (528)
- Phosphorylation of three proteins in the signaling pathway of bacterial chemotaxis (1988) (515)
- Slowed recovery of rod photoresponse in mice lacking the GTPase accelerating protein RGS9-1 (2000) (511)
- Signal transduction pathways involving protein phosphorylation in prokaryotes. (1991) (485)
- Gα15 and Gα16 Couple a Wide Variety of Receptors to Phospholipase C (*) (1995) (468)
- Subunits βγ of heterotrimeric G protein activate β2 isoform of phospholipase C (1992) (460)
- Structure of CheA, a Signal-Transducing Histidine Kinase (1999) (459)
- Construction and characterization of a human bacterial artificial chromosome library. (1996) (433)
- Homologies between signal transducing G proteins and ras gene products. (1984) (410)
- TRPV1-expressing primary afferents generate behavioral responses to pruritogens via multiple mechanisms (2009) (398)
- Activation of G12/G13 Results in Shape Change and Rho/Rho-Kinase–mediated Myosin Light Chain Phosphorylation in Mouse Platelets (1999) (380)
- Repetitive segmental structure of the transducin beta subunit: homology with the CDC4 gene and identification of related mRNAs. (1986) (357)
- Abnormal photoresponses and light-induced apoptosis in rods lacking rhodopsin kinase. (1999) (326)
- Prolonged photoresponses in transgenic mouse rods lacking arrestin (1997) (324)
- A single lentiviral vector platform for microRNA-based conditional RNA interference and coordinated transgene expression (2006) (322)
- Histidine phosphorylation and phosphoryl group transfer in bacterial chemotaxis (1988) (299)
- The entry of diphtheria toxin into the mammalian cell cytoplasm: evidence for lysosomal involvement (1980) (291)
- Recombinational switch for gene expression. (1977) (290)
- Transmembrane signal transduction in bacterial chemotaxis involves ligand-dependent activation of phosphate group transfer. (1989) (285)
- Evolution and organization of the fibrinogen locus on chromosome 4: gene duplication accompanied by transposition and inversion. (1985) (279)
- Stable propagation of cosmid sized human DNA inserts in an F factor based vector. (1992) (273)
- Activation of phospholipase C by the alpha subunits of the Gq and G11 proteins in transfected Cos-7 cells. (1992) (272)
- RGS9 Modulates Dopamine Signaling in the Basal Ganglia (2003) (270)
- Activation of phospholipase C by alpha 1-adrenergic receptors is mediated by the alpha subunits of Gq family. (1992) (269)
- Rapid and Reproducible Deactivation of Rhodopsin Requires Multiple Phosphorylation Sites (2000) (260)
- G protein beta gamma subunits synthesized in Sf9 cells. Functional characterization and the significance of prenylation of gamma. (1992) (258)
- Conserved aspartate residues and phosphorylation in signal transduction by the chemotaxis protein CheY. (1990) (258)
- Characterization of G-protein alpha subunits in the Gq class: expression in murine tissues and in stromal and hematopoietic cell lines. (1991) (257)
- Antibodies to the αq subfamily of guanine nucleotide-binding regulatory protein α subunits attenuate activation of phosphatidylinositol 4,5-bisphosphate hydrolysis by hormones (1991) (243)
- Evidence for two apoptotic pathways in light-induced retinal degeneration (2002) (242)
- Protein histidine kinases and signal transduction in prokaryotes and eukaryotes. (1994) (239)
- Gz, a guanine nucleotide-binding protein with unique biochemical properties. (1990) (235)
- Transposition of structural genes to an expression sequence on a linear plasmid causes antigenic variation in the bacterium Borrelia hermsii (1985) (235)
- Host protein requirements for in vitro site-specific DNA inversion (1986) (234)
- Assembly and function of a quaternary signal transduction complex monitored by surface plasmon resonance (1993) (233)
- A fifth member of the mammalian G-protein beta-subunit family. Expression in brain and activation of the beta 2 isotype of phospholipase C. (1994) (232)
- Thiazolidinediones are acute, specific inhibitors of the mitochondrial pyruvate carrier (2013) (231)
- G alpha 16, a G protein alpha subunit specifically expressed in hematopoietic cells. (1991) (229)
- Hyphal development in Neurospora crassa: involvement of a two-component histidine kinase. (1996) (229)
- Evolution of the mammalian G protein α subunit multigene family (1992) (229)
- Binding of beta gamma subunits of heterotrimeric G proteins to the PH domain of Bruton tyrosine kinase. (1994) (229)
- Measurement by quantitative PCR of changes in HPRT, PGK-1, PGK-2, APRT, MTase, and Zfy gene transcripts during mouse spermatogenesis. (1990) (226)
- G alpha 12 and G alpha 13 subunits define a fourth class of G protein alpha subunits. (1991) (224)
- Defective platelet activation in Gαq-deficient mice (1997) (224)
- Purification from Sf9 cells and characterization of recombinant Gq alpha and G11 alpha. Activation of purified phospholipase C isozymes by G alpha subunits. (1993) (224)
- bcl-2 overexpression reduces apoptotic photoreceptor cell death in three different retinal degenerations. (1996) (224)
- Regulation of lateral flagella gene transcription in Vibrio parahaemolyticus (1986) (222)
- Diphtheria toxin forms transmembrane channels in planar lipid bilayers. (1981) (217)
- Genome sequence of the hyperthermophilic crenarchaeon Pyrobaculum aerophilum (2002) (217)
- Identification of a GTP-binding protein alpha subunit that lacks an apparent ADP-ribosylation site for pertussis toxin. (1988) (215)
- Computer simulation of the phosphorylation cascade controlling bacterial chemotaxis. (1993) (212)
- Defective platelet activation in G alpha(q)-deficient mice. (1997) (212)
- Specific interactions of chemoattractant factor receptors with G-proteins. (1993) (211)
- The photodynamic reaction of methylene blue with deoxyribonucleic acid. (1962) (211)
- NADPH oxidase 2-derived reactive oxygen species in spinal cord microglia contribute to peripheral nerve injury-induced neuropathic pain (2010) (207)
- Primary structure of the M subunit of the reaction center from Rhodopseudomonas sphaeroides. (1983) (199)
- Suppression of LPS-Induced TNF-α Production in Macrophages by cAMP Is Mediated by PKA-AKAP95-p105 (2009) (192)
- A quantitative characterization of the yeast heterotrimeric G protein cycle (2003) (188)
- Regulation by cAMP-dependent protein kinease of a G-protein-mediated phospholipase C (1996) (184)
- Instability of GGL domain-containing RGS proteins in mice lacking the G protein β-subunit Gβ5 (2003) (183)
- Increased susceptibility to light damage in an arrestin knockout mouse model of Oguchi disease (stationary night blindness) (1999) (180)
- Phospholipase Cβ 3 Mediates the Scratching Response Activated by the Histamine H1 Receptor on C-Fiber Nociceptive Neurons (2006) (180)
- Sensory transducers of E. coli are composed of discrete structural and functional domains (1983) (179)
- Protein phosphorylation is involved in bacterial chemotaxis. (1987) (179)
- Histidine and aspartate phosphorylation: two-component systems and the limits of homology. (1994) (178)
- D2 Dopamine Receptors Colocalize Regulator of G-Protein Signaling 9-2 (RGS9-2) via the RGS9 DEP Domain, and RGS9 Knock-Out Mice Develop Dyskinesias Associated with Dopamine Pathways (2005) (178)
- Identification of critical regions on phospholipase C-beta 1 required for activation by G-proteins. (1993) (175)
- Analysis of the nucleotide sequence of an invertible controlling element. (1980) (174)
- Mutations in a C. elegans Gqα Gene Disrupt Movement, Egg Laying, and Viability (1996) (173)
- Phase variation in Salmonella: genetic analysis of a recombinational switch. (1979) (171)
- Bacterial bioluminescence: isolation and expression of the luciferase genes from Vibrio harveyi. (1982) (171)
- Hin-mediated site-specific recombination requires two 26 by recombination sites and a 60 by recombinational enhancer (1985) (170)
- Phase variation: Genetic analysis of switching mutants (1980) (169)
- Phase variation: evolution of a controlling element. (1980) (168)
- Antigenic variation is associated with DNA rearrangements in a relapsing fever borrelia (1985) (167)
- Tissue-specific and developmental regulation of rod opsin chimeric genes in transgenic mice (1991) (167)
- Recoverin Regulates Light-dependent Phosphodiesterase Activity in Retinal Rods (2004) (166)
- The dynamics of protein phosphorylation in bacterial chemotaxis (1990) (166)
- Orphan G protein-coupled receptors MrgA1 and MrgC11 are distinctively activated by RF-amide-related peptides through the Gαq/11 pathway (2002) (165)
- Attenuation of sensory receptor signaling by covalent modification. (1992) (164)
- Retinal degeneration is rescued in transgenic rd mice by expression of the cGMP phosphodiesterase beta subunit. (1992) (163)
- Characterization of Escherichia coli Flagellar Mutants That are Insensitive to Catabolite Repression (1974) (156)
- Genomic Characterization of the Human Heterotrimeric G Protein α, β, and γ Subunit Genes (2000) (155)
- Measuring gene expression with light. (1985) (154)
- Nucleotide binding by the histidine kinase CheA (2001) (153)
- Pertussis Toxin-sensitive Activation of Phospholipase C by the C5a and fMet-Leu-Phe Receptors* (1996) (151)
- Roles of phospholipase C beta2 in chemoattractant-elicited responses. (1997) (147)
- G alpha 15 and G alpha 16 couple a wide variety of receptors to phospholipase C. (1995) (147)
- Isolation and characterization of a cDNA clone for the gamma subunit of bovine retinal transducin. (1984) (145)
- The response regulators CheB and CheY exhibit competitive binding to the kinase CheA. (1995) (142)
- Structure of the serine chemoreceptor in Escherichia coli (1983) (141)
- A Novel Form of the G Protein β Subunit Gβ5 Is Specifically Expressed in the Vertebrate Retina* (1996) (137)
- COS1, a two-component histidine kinase that is involved in hyphal development in the opportunistic pathogen Candida albicans. (1998) (136)
- Distinct forms of the beta subunit of GTP-binding regulatory proteins identified by molecular cloning. (1987) (135)
- Nucleotide sequence of the luxA gene of Vibrio harveyi and the complete amino acid sequence of the alpha subunit of bacterial luciferase. (1986) (134)
- Chromosomal sublocalization of human c-myb and c-fes cellular onc genes (1983) (133)
- Diversity of the G-protein family: Sequences from five additional α subunits in the mouse (1989) (130)
- Chimeric chemosensory transducers of Escherichia coli. (1985) (129)
- Protein phosphorylation in chemotaxis and two-component regulatory systems of bacteria. (1989) (128)
- Chemotaxis in Escherichia coli: methylation of che gene products. (1977) (128)
- New unified nomenclature for the flagellar genes of Escherichia coli and Salmonella typhimurium. (1988) (127)
- RGS-r, a retinal specific RGS protein, binds an intermediate conformation of transducin and enhances recycling. (1996) (126)
- Overview of the Alliance for Cellular Signaling (2002) (125)
- PRR5L degradation promotes MTORC2-mediated PKCδ phosphorylation and cell migration downstream of Gα12 (2012) (125)
- Isolation of the gene encoding the Hin recombinational enhancer binding protein. (1988) (124)
- Mice Lacking G-Protein Receptor Kinase 1 Have Profoundly Slowed Recovery of Cone-Driven Retinal Responses (2000) (122)
- Alternative splicing produces transcripts encoding two forms of the alpha subunit of GTP-binding protein Go. (1990) (122)
- Optimized conditions for pulsed field gel electrophoretic separations of DNA. (1988) (117)
- Transcriptional regulatory regions of testis-specific PGK2 defined in transgenic mice. (1989) (117)
- A G protein gamma subunit shares homology with ras proteins. (1989) (117)
- Pulsed field gel electrophoresis. (1989) (116)
- Phospholipase C β4 is involved in modulating the visual response in mice (1996) (112)
- Surface-enhanced Raman Scattering (SERS) method and instrumentation for genomics and biomedical analysis (1999) (108)
- Expression of CheA fragments which define domains encoding kinase, phosphotransfer, and CheY binding activities. (1993) (108)
- Light-Dependent Translocation of Arrestin in the Absence of Rhodopsin Phosphorylation and Transducin Signaling (2003) (106)
- THE DYE-SENSITIZED PHOTOOXIDATION OF PURINE AND PYRIMIDINE DERIVATIVES. (1964) (102)
- Wolfram Syndrome protein, Miner1, regulates sulphydryl redox status, the unfolded protein response, and Ca2+ homeostasis (2013) (102)
- Regulation of gene expression by site-specific inversion (1978) (101)
- Thrombin Protease-activated Receptor-1 Signals through Gq- and G13-initiated MAPK Cascades Regulating c-Jun Expression to Induce Cell Transformation* (2003) (100)
- Instability of GGL domain-containing RGS proteins in mice lacking the G protein beta-subunit Gbeta5. (2003) (100)
- Nucleotide sequence corresponding to five chemotaxis genes in Escherichia coli (1986) (99)
- Genomic characterization of the human heterotrimeric G protein alpha, beta, and gamma subunit genes. (2000) (99)
- G protein diversity is increased by associations with a variety of gamma subunits. (1990) (99)
- The G alpha q and G alpha 11 proteins couple the thyrotropin-releasing hormone receptor to phospholipase C in GH3 rat pituitary cells. (1992) (98)
- Chromosomal mapping of the mink cell focus-inducing and xenotropic env gene family in the mouse. (1983) (98)
- Synthesis of a sequence-specific DNA-cleaving peptide. (1987) (95)
- G alpha q family members couple parathyroid hormone (PTH)/PTH-related peptide and calcitonin receptors to phospholipase C in COS-7 cells. (1996) (95)
- Caenorhabditis elegans Galphaq regulates egg-laying behavior via a PLCbeta-independent and serotonin-dependent signaling pathway and likely functions both in the nervous system and in muscle. (2003) (94)
- Embryonic cardiomyocyte hypoplasia and craniofacial defects in G alpha q/G alpha 11-mutant mice. (1998) (94)
- Co-expression of Gβ5 Enhances the Function of Two Gγ Subunit-like Domain-containing Regulators of G Protein Signaling Proteins* (2000) (93)
- The solution structure and interactions of CheW from Thermotoga maritima (2002) (90)
- Developmental regulation of expression of the lactate dehydrogenase (LDH) multigene family during mouse spermatogenesis. (1990) (89)
- Prolonged Photoresponses and Defective Adaptation in Rods of Gβ5-/- Mice (2003) (88)
- Flagellar Assembly Mutants in Escherichia coli (1972) (88)
- Analysis of cellular and behavioral responses to imiquimod reveals a unique itch pathway in transient receptor potential vanilloid 1 (TRPV1)-expressing neurons (2011) (87)
- RGS9-1 is required for normal inactivation of mouse cone phototransduction. (2001) (85)
- Identification of an alternative Gαq-dependent chemokine receptor signal transduction pathway in dendritic cells and granulocytes (2007) (84)
- Localization of proteins controlling motility and chemotaxis in Escherichia coli (1977) (84)
- Identification of polypeptides necessary for chemotaxis in Escherichia coli (1977) (83)
- Modules in the Photoreceptor RGS9-1·Gβ 5L GTPase-accelerating Protein Complex Control Effector Coupling, GTPase Acceleration, Protein Folding, and Stability* (2000) (83)
- Molecular Mechanism of the Inhibition of Phospholipase C β3 by Protein Kinase C* (2000) (82)
- Activation of the phosphosignaling protein CheY. II. Analysis of activated mutants by 19F NMR and protein engineering. (1993) (81)
- The carboxy-terminal portion of the CheA kinase mediates regulation of autophosphorylation by transducer and CheW (1993) (81)
- Fis binding to the recombinational enhancer of the Hin DNA inversion system. (1987) (80)
- Evolution of the mammalian G protein alpha subunit multigene family. (1992) (79)
- Mutations in a C. elegans Gqalpha gene disrupt movement, egg laying, and viability. (1996) (78)
- Diversity among the beta subunits of heterotrimeric GTP-binding proteins: characterization of a novel beta-subunit cDNA. (1992) (78)
- Crystal structures of CheY from Thermotoga maritima do not support conventional explanations for the structural basis of enhanced thermostability (1998) (76)
- Determining transcript number using the polymerase chain reaction: Pgk-2, mP2, and PGK-2 transgene mRNA levels during spermatogenesis. (1991) (76)
- Mutants defective in bacterial chemotaxis show modified protein phosphorylation (1988) (75)
- Constitutively Active Gαq and Gα13 Trigger Apoptosis through Different Pathways* (1997) (74)
- Chemotactic control of the two flagellar systems of Vibrio parahaemolyticus (1990) (74)
- NMR studies of the phosphotransfer domain of the histidine kinase CheA from Escherichia coli: assignments, secondary structure, general fold, and backbone dynamics. (1995) (74)
- Genetic Analysis of Flagellar Mutants in Escherichia coli (1973) (72)
- High-resolution restriction maps of bacterial artificial chromosomes constructed by optical mapping. (1998) (70)
- Purification and characterization of recombinant G16 alpha from Sf9 cells: activation of purified phospholipase C isozymes by G-protein alpha subunits. (1993) (70)
- Differential gene expression during mouse spermatogenesis. (1989) (69)
- Multiple regions of G alpha 16 contribute to the specificity of activation by the C5a receptor. (1995) (69)
- Phosphorylation assays for proteins of the two-component regulatory system controlling chemotaxis in Escherichia coli. (1991) (67)
- Purification and Thermal Stability of Intact Bacillus subtilis Flagella (1971) (67)
- In different organisms, the mode of interaction between two signaling proteins is not necessarily conserved. (2004) (66)
- Transposon mutagenesis of marine Vibrio spp (1984) (66)
- Interaction of Gα12 with Gα13 and Gαq signaling pathways (2002) (66)
- Spatial relationship of the Fis binding sites for Hin recombinational enhancer activity (1987) (66)
- Primary structure of the L subunit of the reaction center from Rhodopseudomonas sphaeroides. (1984) (65)
- Gαi2-mediated signaling events in the endothelium are involved in controlling leukocyte extravasation (2007) (65)
- Human genome anatomy: BACs integrating the genetic and cytogenetic maps for bridging genome and biomedicine. (1999) (64)
- Analysis of the Major Patterns of B Cell Gene Expression Changes in Response to Short-Term Stimulation with 33 Single Ligands1 (2004) (64)
- A fosmid-based genomic map and identification of 474 genes of the hyperthermophilic archaeonPyrobaculum aerophilum (1997) (64)
- Direct genetic demonstration of G alpha 13 coupling to the orphan G protein-coupled receptor G2A leading to RhoA-dependent actin rearrangement. (2000) (62)
- Sensory transducers of E. coli are encoded by homologous genes (1981) (61)
- The identification of the mot gene product with Escherichia coli-lambda hybrids. (1976) (61)
- A versatile approach to multiple gene RNA interference using microRNA-based short hairpin RNAs (2007) (61)
- Organization of transmembrane signalling by heterotrimeric G proteins. (1996) (61)
- Activation of the phosphosignaling protein CheY. I. Analysis of the phosphorylated conformation by 19F NMR and protein engineering. (1993) (59)
- The human blue opsin promoter directs transgene expression in short-wave cones and bipolar cells in the mouse retina. (1994) (59)
- Importance of minor-groove contacts for recognition of DNA by the binding domain of Hin recombinase. (1990) (58)
- Deactivation of Phosphorylated and Nonphosphorylated Rhodopsin by Arrestin Splice Variants (2006) (57)
- DNA sequence adjacent to flagellar genes and evolution of flagellar-phase variation (1983) (57)
- Cloning of the Vibrio harveyi luciferase genes: use of a synthetic oligonucleotide probe. (1983) (56)
- Genetic analysis of mammalian G-protein signalling (1998) (56)
- Insertion of diphtheria toxin into and across membranes: role of phosphoinositide asymmetry (1982) (56)
- Complete nucleotide sequence of two generations of a bacterial artificial chromosome cloning vector. (1997) (55)
- Novel Form of Adaptation in Mouse Retinal Rods Speeds Recovery of Phototransduction (2003) (55)
- Operon controlling motility and chemotaxis in E. coli (1976) (55)
- Archaeal ubiquity. (1996) (54)
- Synthesis of mot and che gene products of Escherichia coli programmed by hybrid ColE1 plasmids in minicells (1977) (54)
- Retarding photoreceptor degeneration in Pdegtm1/Pdegtml mice by an apoptosis suppressor gene. (1997) (54)
- Division Mutants of Bacillus subtilis: Isolation and PBS1 Transduction of Division-Specific Markers (1971) (54)
- Molecular architecture of Gαo and the structural basis for RGS16-mediated deactivation (2008) (53)
- Functional Analysis of a Dominant Negative Mutant of Gαi2(*) (1995) (52)
- Identification, chromosomal location, and genome organization of mammalian G-protein-coupled receptors. (1993) (52)
- Flagellar-phase variation: isolation of the rh1 gene (1979) (52)
- Group I Metabotropic Glutamate Receptor Signaling via Gαq/Gα11 Secures the Induction of Long-Term Potentiation in the Hippocampal Area CA1 (2002) (52)
- The 35- and 36-kDa beta subunits of GTP-binding regulatory proteins are products of separate genes. (1988) (51)
- The Ca2+-dependent Binding of Calmodulin to an N-terminal Motif of the Heterotrimeric G Protein β Subunit* (1997) (50)
- Deciphering Signaling Outcomes from a System of Complex Networks (2009) (50)
- Protein phosphorylation and bacterial chemotaxis. (1988) (50)
- A bacterial artificial chromosome-based framework contig map of human chromosome 22q. (1996) (50)
- Analysis of C5a-mediated chemotaxis by lentiviral delivery of small interfering RNA. (2004) (49)
- Localization of the human myelin basic protein gene (MBP) to region 18q22----qter by in situ hybridization. (1985) (49)
- Synthesis of a site-specific DNA-binding peptide. (1987) (49)
- Genetic Analysis of Bacteriophage Mu-Induced Flagellar Mutants in Escherichia coli (1973) (48)
- DNA-binding properties of the Hin recombinase. (1989) (47)
- Analysis of the 1.1-Mb Human α/δ T-Cell Receptor Locus with Bacterial Artificial Chromosome Clones (1997) (47)
- Silencing the expression of multiple Gbeta-subunits eliminates signaling mediated by all four families of G proteins. (2005) (47)
- COS-l, a putative two-component histidine kinase of Candida albicans, is an in vivo virulence factor. (2001) (46)
- Selective Inhibition of Human α-Thrombin by Cobalt(III) Schiff Base Complexes (1998) (46)
- Phosphotransfer and CheY-binding domains of the histidine autokinase CheA are joined by a flexible linker. (1996) (45)
- Expression of flagellar genes carried by bacteriophage lambda (1976) (44)
- Synergistic Ca2+ Responses by Gαi- and Gαq-coupled G-protein-coupled Receptors Require a Single PLCβ Isoform That Is Sensitive to Both Gβγ and Gαq* (2010) (44)
- Mutations in the chemotactic response regulator, CheY, that confer resistance to the phosphatase activity of CheZ (1995) (42)
- Signaling and Cross-talk by C5a and UDP in Macrophages Selectively Use PLCβ3 to Regulate Intracellular Free Calcium* (2008) (41)
- Analysis of the functional components of the phase variation system. (1981) (41)
- Genes for the hook-basal body proteins of the flagellar apparatus in Escherichia coli (1978) (41)
- CHAPTER 12 – Phase Variation and Related Systems (1983) (40)
- BAC and PAC contigs covering 3.5 Mb of the Down syndrome congenital heart disease region between D21S55 and MX1 on chromosome 21. (1997) (40)
- The Retinal Specific Protein RGS-r Competes with the γ Subunit of cGMP Phosphodiesterase for the α Subunit of Transducin and Facilitates Signal Termination* (1997) (40)
- Synergistic effect of Bcl-2 and BAG-1 on the prevention of photoreceptor cell death. (2000) (40)
- Phase variation in Salmonella: analysis of Hin recombinase and hix recombination site interaction in vivo. (1988) (40)
- Thermostable chemotaxis proteins from the hyperthermophilic bacterium Thermotoga maritima (1996) (39)
- Downregulation of cGMP phosphodiesterase induced by expression of GTPase-deficient cone transducin in mouse rod photoreceptors. (1994) (38)
- Localized perturbations in CheY structure monitored by NMR identify a CheA binding interface (1995) (38)
- Requirements for the translocation of diphtheria toxin fragment A across lipid membranes. (1985) (38)
- Helical shifts generate two distinct conformers in the atomic resolution structure of the CheA phosphotransferase domain from Thermotoga maritima. (2004) (37)
- Structural and Chemical Requirements for Histidine Phosphorylation by the Chemotaxis Kinase CheA* (2005) (37)
- Diphtheria toxin has the properties of a lectin. (1978) (36)
- Interferon induction: DNA-RNA hybrid or double stranded RNA? (1971) (36)
- Synthesis of Bacterial Flagella II. PBSl Transduction of Flagella-specific Markers in Bacillus subtilis (1969) (36)
- Purification and Partial Characterization of Bacillus subtilis Flagellar Hooks (1971) (35)
- Identification of the structural gene for the hook subunit protein of Escherichia coli flagella (1978) (35)
- Characterization of Escherichia coli chemotaxis receptor mutants with null phenotypes (1986) (35)
- Pulsed field gel electrophoresis techniques for separating 1- to 50-kilobase DNA fragments. (1989) (35)
- Expression of rhodopsin promoter transgene product in both rods and cones. (1994) (35)
- Phospholipase C beta 4 is involved in modulating the visual response in mice. (1996) (34)
- PHOTOSENSITIZED REACTION OF POLYRIBONUCLEOTIDES. I. EFFECTS ON THEIR SUSCEPTIBILITY TO ENZYME DIGESTION AND THEIR ABILITY TO ACT AS SYNTHETIC MESSENGERS. (1965) (33)
- Characterization of a Goα Mutant That Binds Xanthine Nucleotides* (1997) (33)
- Coupling of receptor function to phosphate-transfer reactions in bacterial chemotaxis. (1991) (33)
- Cloning of the C-terminal cytoplasmic fragment of the tar protein and effects of the fragment on chemotaxis of Escherichia coli (1988) (33)
- Molecular mechanism of the inhibition of phospholipase C beta 3 by protein kinase C. (2000) (33)
- Cloning multigene families with degenerate PCR primers (1991) (31)
- Neurobiology of Disease D 2 Dopamine Receptors Colocalize Regulator of G-Protein Signaling 9-2 ( RGS 9-2 ) via the RGS 9 DEP Domain , and RGS 9 Knock-Out Mice Develop Dyskinesias Associated with Dopamine Pathways (2005) (31)
- In vivo and in vitro characterization of Escherichia coli protein CheZ gain- and loss-of-function mutants (1996) (31)
- In vitro analysis of Hin-mediated site-specific recombination. (1984) (31)
- Phase variation and the Hin protein: in vivo activity measurements, protein overproduction, and purification (1984) (30)
- Chromosomal mapping of murine c-fes and c-src genes (1984) (30)
- Mutational analysis of G protein α subunit Goα expressed in Escherichia coli (1993) (30)
- Gαq-containing G proteins regulate B cell selection and survival and are required to prevent B cell–dependent autoimmunity (2010) (29)
- Identification of small molecule antagonists of the human mas-related gene-X1 receptor. (2006) (29)
- Variability in G-protein-coupled signaling studied with microfluidic devices. (2010) (29)
- Genetic Control of Bacterial Adhesion (1984) (28)
- Characterization of lambda Escherichia coli hybrids carrying chemotaxis genes (1977) (28)
- Orientation of the putative recognition helix in the DNA-binding domain of Hin recombinase complexed with the hix site. (1990) (28)
- Structure of the bovine transducin gamma subunit gene and analysis of promoter function in transgenic mice. (1993) (28)
- Enhancers of site-specific recombination in bacteria (1987) (27)
- Gene expression profiles of light-induced apoptosis in arrestin/rhodopsin kinase-deficient mouse retinas (2001) (27)
- Irreversible enzymatic inhibition by cobalt chelate complexes (1995) (27)
- Signal Transduction: Bringing the eukaryotes up to speed (1994) (27)
- Comparative analysis of transcriptional profiles between two apoptotic pathways of light-induced retinal degeneration (2004) (26)
- Inhibition of Subsets of G Protein-coupled Receptors by Empty Mutants of G Protein α Subunits in Go, G11, and G16 * (2000) (26)
- Positioning Flagellar Genes in Escherichia coli by Deletion Analysis (1974) (26)
- Isolation and in Vitro Characterization of CheZ Suppressors for the Escherichia coli Chemotactic Response Regulator Mutant CheYN23D (*) (1996) (26)
- Classification of Bacillus subtilis flagellins (1977) (25)
- Interaction of the Xanthine Nucleotide Binding Goα Mutant with G Protein-coupled Receptors* (1998) (25)
- The regulation of flagellar formation and function. (1974) (24)
- A segment of the C-terminal half of the G-protein beta 1 subunit specifies its interaction with the gamma 1 subunit. (1995) (24)
- G 13 is an essential mediator of platelet activation in hemostasis and thrombosis (24)
- Hao, W. et al. Evidence for two apoptotic pathways in light-induced retinal degeneration. Nat. Genet. 32, 254-260 (2002) (24)
- Two-component signaling systems (2007) (23)
- Characterization of a porin from the outer membrane of Vibrio anguillarum (1996) (22)
- Genetic analysis of Escherichia coli K-12 region I flagellar mutants (1977) (22)
- Recombinational Regulation of Gene Expression in Bacteria (1983) (22)
- Phosphorylation and regulation of G-protein beta-gamma-activated phospholipase C-beta-2 by cAMP-dependent protein kinase (1996) (22)
- Uncoupled Phosphorylation and Activation in Bacterial Chemotaxis (1997) (21)
- Fluorescence-based sequencing directly from bacterial and P1-derived artificial chromosomes. (1997) (21)
- The role of negative supercoiling in Hin-mediated site-specific recombination. (1992) (21)
- Methacholine-induced airway hyperresponsiveness is dependent on Gαq signaling (2003) (20)
- Intracellular signaling and the origins of the sensations of itch and pain. (2011) (20)
- Polarity Exchange at the Interface of Regulators of G Protein Signaling with G Protein α-Subunits* (2000) (20)
- A third P-domain peptide gene (TFF3), human intestinal trefoil factor, maps to 21q22.3. (1996) (20)
- Mapping and gene order of U1 small nuclear RNA, endogenous viralenv sequence, amylase, and alcohol dehydrogenase-3 on mouse chromosome 3 (1988) (18)
- Desensitization of Inositol 1,4,5-Trisphosphate/Ca2+-induced Cl− Currents by Prolonged Activation of G Proteins in Xenopus Oocytes* (1996) (18)
- A 12-Mb complete coverage BAC contig map in human chromosome 16p13.1-p11.2. (1999) (18)
- Bacterial flagella. (1977) (18)
- Structure and Function of CheA, the Histidine Kinase Central to Bacterial Chemotaxis (2003) (18)
- The retinal specific protein RGS-r competes with the gamma subunit of cGMP phosphodiesterase for the alpha subunit of transducin and facilitates signal termination. (1997) (18)
- Dual Ligand Stimulation of RAW 264.7 Cells Uncovers Feedback Mechanisms That Regulate TLR-Mediated Gene Expression123 (2006) (18)
- The transforming activity of activated G alpha 12. (1993) (17)
- Antigenic Nature of Bacterial Flagellar Hook Structures (1970) (17)
- Cloning and expression of the flagellar hook gene on hybrid plasmids in minicells (1977) (16)
- Diversity of the G-protein family: sequences from five additional alpha subunits in the mouse. (1989) (16)
- Characterization of a human chromosome 22 enriched bacterial artificial chromosome sublibrary. (1995) (16)
- Synthesis of Bacterial Flagella I. Requirement for Protein and Ribonucleic Acid Synthesis During Flagellar Regeneration in Bacillus subtilis (1968) (16)
- The Alliance for Cellular Signaling Plasmid Collection (2007) (16)
- Gq signaling is required for allergen-induced pulmonary eosinophilia. (2002) (14)
- CA-repeat polymorphism at the D22S430 locus adjacent to NF2. (1993) (14)
- Framework for a physical map of the human 22q13 region using bacterial artificial chromosomes (BACs). (1996) (14)
- Genetic analysis of the mechanism of the salmonella phase variation site specific recombination system (2004) (14)
- Construction and utility of a human chromosome 22-specific Fosmid library. (1995) (14)
- Analysis of the 1.1-Mb human alpha/delta T-cell receptor locus with bacterial artificial chromosome clones. (1997) (14)
- Genetic Analysis of Escherichia coli (2003) (13)
- The basis of high resolution separation of small DNAs by asymmetric-voltage field inversion electrophoresis and its application to DNA sequencing gels. (1990) (13)
- The Mechanism of Phase Variation (1980) (13)
- Use of Radioactive Antibodies for Characterizing Antigens and Application to the Study of Flagella Synthesis (1968) (13)
- Homology between the invertible deoxyribonucleic acid sequence that controls flagellar-phase variation in Salmonella sp. and deoxyribonucleic acid sequences in other organisms (1981) (13)
- Selection of chromosome 22-specific clones from human genomic BAC library using a chromosome-specific cosmid library pool. (1994) (12)
- Bax is not the heterodimerization partner necessary for sustained anti-photoreceptor-cell-death activity of Bcl-2. (2002) (12)
- The effects of symmetrical recombination site hixC on Hin recombinase function. (1992) (12)
- Gq Signaling Is Required for Allergen-Induced Pulmonary Eosinophilia1 (2002) (12)
- Conditionally expressed Gα15 couples to endogenous receptors in GH3 cells (2001) (11)
- Studies of the diphtheria toxin receptor on Chinese hamster cells. (1978) (11)
- A human chromosome 22 fosmid resource: mapping and analysis of 96 clones. (1996) (10)
- Methacholine-induced airway hyperresponsiveness is dependent on Galphaq signaling. (2003) (10)
- Selection of a sublibrary enriched for a chromosome from total human bacterial artificial chromosome library using DNA from flow sorted chromosomes as hybridization probes. (1995) (10)
- Assembly of Hybrid Flagellar Filaments (1974) (10)
- Variation in the Primary Structure of Bacillus subtilis Flagellins (1971) (10)
- The Specificity of Interferon Induction (1971) (10)
- Intracellular Signaling and the Origins of the Sensations of Itch and Pain (2011) (10)
- Purification and characterization of the wild-type and mutant carboxy-terminal domains of the Escherichia coli Tar chemoreceptor (1988) (10)
- A high resolution integrated yeast artificial chromosome clone map of human chromosome 22. (1995) (10)
- Chapter 1 Sensory Transduction in Bacteria (1985) (9)
- Dysfunctional genomics: BACs to the rescue (1997) (9)
- Distinct Forms of the ß Subunit of GTP-Binding Regulatory Proteins Identified by Molecular (9)
- Synthesis of Bacterial Flagella: Chromosomal Synchrony and Flagella Synthesis (1969) (7)
- Random Mutagenesis of G protein a Subunit Goa MUTATIONS ALTERING NUCLEOTIDE BINDING* (2001) (7)
- Random cysteine disulfide crosslinking in the analysis of protein structure (1991) (6)
- Methods in enzymology index (1995) (6)
- Signal Transduction in Microorganisms (1995) (6)
- Transposon Mutagenesis ofMarineVibrio spp. (1984) (6)
- Mutational analysis of G protein alpha subunit G(o) alpha expressed in Escherichia coli. (1993) (6)
- Transcriptional regulatory regions of testis-specific PGK 2 defined in transgenic mice ( spermatogenesis / translational regulation / luciferase ) MURRAY 0 (5)
- Activation of phospholipase C 132 by the av and 13 y subunits of trimeric GTP-binding protein (2005) (5)
- Alternative splicing produces transcripts encoding two forms of the a subunit of GTP-binding protein G 0 ( guanine nucleotide-binding protein / signal transduction ) (5)
- fosmid-based genomic map and identification of 474 genes of the hyperthermophilic archaeon (5)
- Signaling and Cross-talk by C5a and UDP in Macrophages Selectively Use PLC3 to Regulate Intracellular (2008) (5)
- Identification oftheStructural GenefortheHookSubunit Protein ofEscherichia coli Flagella (1978) (5)
- Functional analysis of a dominant negative mutant of G alpha i2. (1995) (4)
- Genetic Analysis ofBacteriophage Mu-Induced Flagellar MutantsinEscherichia coli (1973) (4)
- Bipolar Cells in the Mouse Retina The Human Blue Opsin Promoter Directs Transgene Expression in Short-Wave Cones and (2006) (4)
- A FAMILY OF HOMOLOGOUS GENES ENCODING SENSORY TRANSDUCERS IN E. COLI (1983) (3)
- DIPHTHERIA TOXIN INTERACTIONS WITH AN INHIBITORY ACTIVITY FROM PLASMA MEMBRANES (1981) (3)
- Crystallization and preliminary X-ray analysis of the DNA binding domain of the Hin recombinase with its DNA binding site. (1993) (3)
- Conditionally expressed G alpha 15 couples to endogenous receptors in GH3 cells. (2001) (2)
- Transgenic Mouse Studies of Retinal Degeneration: Expression of The β-Subunit of cGMP Phosphodiesterase and Transducin α-Subunits (1993) (2)
- [7] Photosensitized oxidation of purines and pyrimidines (1967) (2)
- Alfred Gilman (1941–2015) (2016) (1)
- Evidence for Two Pathways Leading to Light-Induced Retinal Degeneration (2002) (1)
- Muscarinic M1 inhibition of calcium current, but not M-type potassium current, is reduced in G alpha q knockout mice (1998) (1)
- Gal 2 and Ga 13 subunits define a fourth class of G protein a subunits ( GTP-binding protein / signal transduction (1)
- Untangling Dendrites with Quantitative Models (2000) (1)
- Extravasation of Leukocytes from Circulation is Controlled by Gαi2 Signaling Events in the Endothelium (2007) (1)
- Light Induced Photoreceptor Apoptosis: Is Phototransduction Involved? (2002) (1)
- Cellular and bioenergetic dysfunction induced by loss of the Wolfram Syndrome protein, Miner1, can be reversed by treatment with N-acetylcysteine (2013) (1)
- I Metabotropic Glutamate Receptor Signaling via G q / G 11 Secures the Induction of Long-Term Potentiation in the Hippocampal Area CA 1 (2002) (1)
- Expression of the Bacillus subtilis spolVB gene is under dual aF / aG control (2008) (1)
- Microbial role in biodeterioration: genetic approaches (1988) (1)
- Regulate TLR-Mediated Gene Expression Uncovers Feedback Mechanisms That Dual Ligand Stimulation of RAW 264 . 7 Cells (2006) (1)
- Phospholipase beta-4-knockout mouse exhibits retinal phenotype (1996) (1)
- Analysis of C 5 a-mediated chemotaxis by lentiviral delivery of small interfering RNA (2004) (1)
- Effects of Blue- and Green Light in Arrestin / Rhodopsinkinase Double Knock Out (Arr-/- / RK -/-) Mice (2003) (1)
- Synergistic Ca 2 Responses by G i - and G q -coupled G-protein-coupled Receptors Require a Single PLC Isoform (2011) (1)
- Cloning and expression of the flagellar hook gene on hybird plasmids in minicells. (1977) (0)
- Identification of Related mRNAs Repetitive Segmental Structure of the Transducin ß Subunit : Homology with the CDC 4 Gene and (2003) (0)
- Subject Index, Vol. 72, 1996 (1996) (0)
- Biopolymers: protein and nucleic acids. Annual report, 15 September 1987-14 September 1988 (1988) (0)
- Biopolymers: Proteins and Nucleic Acids. (1990) (0)
- PhaseVariation andtheHinProtein: InVivoActivity Measurements, Protein Overproduction, andPurification (1984) (0)
- [Developing a physical map of human chromosome 22]. Progress report (1991) (0)
- Assembly ofHybridFlagellar Filaments (1974) (0)
- An integrated BAC/PAC molecular cytogenetic resource for human genetics: Applications to disease (1996) (0)
- 303 Multiple climbing fiber innervation of cerebellar purkinje cells in mutant mice lacking the α-subunit of geterotrimeric G protein Gq(Gαq) (1997) (0)
- STRUCTURE OF CHEA DOMAIN P4 IN COMPLEX WITH TNP-ATP (2001) (0)
- STRUCTURE OF SIGNAL TRANSDUCTION PROTEIN CHEY (1997) (0)
- Immobilized Enzymes and Cells. Vol. 137, Pt. D (1988) (0)
- Genome rearrangement: Proceedings of the UCLA symposium held at Steamboat Springs, Colorado, April 7-13, 1984 (1985) (0)
- Retinal Degeneration in Transgenic Mouse Expressing the N-terminal Domain of RGS9 (2002) (0)
- The Gar , and Garll Proteins Couple the Thyrotropin-releasing Hormone Receptor to Phospholipase C in GH 3 Rat Pituitary Cells * (2001) (0)
- STRUCTURE OF CHEA DOMAIN P4 IN COMPLEX WITH ADPCP AND MANGANESE (2001) (0)
- Control of Caenorhabditis Elegans Behaviour and Development by G Proteins Big and Small (2004) (0)
- Toward an Integrated BAC Library Resource for Genome Sequencing and Analysis (2002) (0)
- Detecting Mitochondrial Genotypes by Temperature Gradient Gel Electrophoresis and Heteroduplex Analysis (1999) (0)
- Acute, pharmacologic inhibition of the mitochondrial pyruvate carrier enhances cellular glucose uptake and potentiates metabolic flexibility (2013) (0)
- Bipolymers: Proteins and Nucleic Acids. (1995) (0)
- Thebasis ofhighresolution separation ofsmall DNAsby asymmetric-volta ge field inversion electrophoresis andits application toDNAsequencing gels (1990) (0)
- Chimeric chemosensory transducers of Escherichia coli ( chemotaxls / methyl-accepting chemotaxls proteins / gene family / gene fusion ) (0)
- Accompanied by Transposition and Inversion Evolution and Organization of the Fibrinogen Locus on Chromosome 4 : Gene Duplication (0)
- Biochemistry of Bacterial Flagella (1973) (0)
- in Vibrio parahaemolyticus. Regulation of lateral flagella gene transcription (2013) (0)
- Chemotactic Control oftheTwoFlagellar Systems of (1990) (0)
- Final Report: Complete Sequencing of the 2.3Mbp Genome of the Hyperthermophilic Archaeon Pyrbaculum Aerophilum, January 1, 1998 - December 31, 1998 (1998) (0)
- An Integrated BAC/PAC Resource for identifying chromosomal abnormalities in solid tumors (2000) (0)
- Developing a physical map of human chromosome 22) (1991) (0)
- Activation of Phosphate Group Transfer Transmembrane Signal Transduction in Bacterial Chemotaxis Involves Ligand-Dependent (2006) (0)
- Purification andCharacterization oftheWild-Type andMutant Carboxy-Terminal Domains oftheEscherichia coli TarChemoreceptor (1988) (0)
- Characterization ofEscherichia coli Chemotaxis Receptor Mutants withNullPhenotypes (1986) (0)
- Xanthine nucleotide binding Go alpha mutant (1996) (0)
- Studies of the diphtheria toxin receptor (1978) (0)
- Activation and Densensitization in Bacterial Chemotaxis (1990) (0)
- Synthesis ofBacterial Flagella: Chromosomal Synchrony andFlagella Synthesis (1969) (0)
- [Developing a physical map of human chromosome 22 using Pace electrophoresis and large fragment cloning]. Annual report, October 1, 1989--September 30, 1990 (1990) (0)
- STRUCTURE OF THE HISTIDINE KINASE CHEA ATP-BINDING DOMAIN IN COMPLEX WITH ADPNP AND MAGENSIUM (2001) (0)
- CRYSTAL STRUCTURE OF CHEA-289, A SIGNAL TRANSDUCING HISTIDINE KINASE (1999) (0)
- Genetic Analysis ofFlagellar Mutantsin Escherichia coli (1973) (0)
- Chemotaxis in Escherichia col: Methylation of che gene pmoducts (2003) (0)
- Subject Index Vol. 39, 1985 (1985) (0)
- Cumulative subject index, volumes 290-319. (2000) (0)
- autophosphorylation by transducer and CheW. kinase mediates regulation of The carboxy-terminal portion of the CheA (2013) (0)
- A segment of the C-terminal half of the G-protein . 31 subunit specifies its interaction with the y 4 subunit ( signal transduction / phospholipase / fty dimers (0)
- Mixed g-protein composition and its use (1997) (0)
- ADP-Ribosylation Site for Pertussis Toxin Identification of a GTP-Binding Protein alpha Subunit that Lacks an Apparent (2006) (0)
- Chemotaxis kinase CheA P2 domain in complex with response regulator CheY from the thermophile thermotoga maritima (2004) (0)
- Development of BAC libraries and integrated physical mapping of human chromosome 22 using BACs. Annual report, July 1994--June 1995 (1995) (0)
- Methods in enzymology on CD-ROM, CD-1 : recombinant DNA and related methodology (1995) (0)
- [Melting in adsorbed films]. Progress report 1992 (1992) (0)
- Diphtheria toxin inhibitory activity from rabbit liver plasma membranes (1979) (0)
- Biopolymers: Protein and Nucleic Acids (1987) (0)
- Instability of GGL Domain-containing RGS Proteins in Mice Lacking the Fifth Member of the G-protein Beta Subunit (2003) (0)
- Erratum: (Journal of General Physiology (June 2004) 123:6 (729-741) ) (2005) (0)
- Biomembranes : Vol. 156, Pt. P: ATP-Driven Pumps and Related Transport - The Na,K-Pump (1988) (0)
- Platelets : Vol. 215, Pt. B: Receptors, Adhesion, Secretion (1992) (0)
- Correction (2005) (0)
- STRUCTURE OF THE HISTIDINE KINASE CHEA ATP-BINDING DOMAIN IN COMPLEX WITH ATP ANALOG ADPCP AND MAGNESIUM (2001) (0)
- Solution structure of the chemotaxis protein CheW from the thermophilic organism Thermotoga maritima (2002) (0)
- CheA phosphotransferase domain from Thermotoga maritima (2004) (0)
- and purification. overproduction, activity measurements, protein Phase variation and the Hin protein: in vivo (2013) (0)
- 302 Multiple climbing fiber innervation of cerebellar purkinje cells in mutant mice lacking the phospholipase C-β4 (PLC β4) (1997) (0)
- A Correction to the Perspective Titled: “Intracellular Signaling and the Origins of the Sensations of Itch and Pain” by S.-K. Han and M. I. Simon (2011) (0)
- Melting in adsorbed films (1992) (0)
- Biomembranes : Vol. 191, Pt. V: Cellular and Subcellular Transport - Epithelial Cells (1990) (0)
- PNAS Paper: Rules and Standard Practice (1990) (0)
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