Michael J. Weber
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Michael J. Weberbiology Degrees
Biology
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Molecular Biology
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Biochemistry
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Biology
Michael J. Weber's Degrees
- PhD Molecular Biology University of California, San Francisco
- Bachelors Biochemistry University of California, Berkeley
Why Is Michael J. Weber Influential?
(Suggest an Edit or Addition)Michael J. Weber's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt (1997) (1112)
- Identification of the regulatory phosphorylation sites in pp42/mitogen‐activated protein kinase (MAP kinase). (1991) (977)
- Complexes of Ras.GTP with Raf-1 and mitogen-activated protein kinase kinase. (1993) (948)
- Inhibition of the EGF-activated MAP kinase signaling pathway by adenosine 3',5'-monophosphate. (1993) (930)
- Requirement for MAP kinase (ERK2) activity in interferon alpha- and interferon beta-stimulated gene expression through STAT proteins. (1995) (579)
- Activation of mitogen-activated protein kinase associated with prostate cancer progression. (1999) (559)
- MP1: a MEK binding partner that enhances enzymatic activation of the MAP kinase cascade. (1998) (476)
- Conditional transformation of cells and rapid activation of the mitogen-activated protein kinase cascade by an estradiol-dependent human raf-1 protein kinase (1993) (372)
- Evidence that pp42, a major tyrosine kinase target protein, is a mitogen-activated serine/threonine protein kinase. (1989) (350)
- Hexose transport in normal and in Rous sarcoma virus-transformed cells. (1973) (238)
- Reversal of Raf-1 activation by purified and membrane-associated protein phosphatases. (1995) (199)
- A proline-rich sequence unique to MEK1 and MEK2 is required for raf binding and regulates MEK function (1995) (198)
- Identification by mass spectrometry of threonine 97 in bovine myelin basic protein as a specific phosphorylation site for mitogen-activated protein kinase. (1990) (190)
- Antiapoptotic signaling in LNCaP prostate cancer cells: a survival signaling pathway independent of phosphatidylinositol 3'-kinase and Akt/protein kinase B. (1999) (171)
- The serine/threonine protein kinase, p90 ribosomal S6 kinase, is an important regulator of prostate cancer cell proliferation. (2005) (170)
- Complete sequence of a cDNA encoding an active rat choline acetyltransferase: A tool to investigate the plasticity of cholinergic phenotype expression (1989) (167)
- A2B Adenosine and P2Y2 Receptors Stimulate Mitogen-activated Protein Kinase in Human Embryonic Kidney-293 Cells (1999) (166)
- Genetics of src: structure and functional organization of a protein tyrosine kinase. (1989) (160)
- Transforming growth factor beta 1 is a potent survival factor for rat embryo motoneurons in culture. (1990) (155)
- Identification and characterization of a new mammalian mitogen-activated protein kinase kinase, MKK2 (1993) (151)
- Ras-induced activation of Raf-1 is dependent on tyrosine phosphorylation (1996) (147)
- Atrial Natriuretic Peptide Inhibits Mitogen-activated Protein Kinase through the Clearance Receptor (1996) (142)
- RAS and RAF-1 form a signalling complex with MEK-1 but not MEK-2 (1994) (135)
- Activation of the oncogenic potential of the avian cellular src protein by specific structural alteration of the carboxy terminus. (1987) (133)
- In situ visualization of intratumor growth factor signaling: immunohistochemical localization of activated ERK/MAP kinase in glial neoplasms. (1998) (133)
- Dual phosphorylation and autophosphorylation in mitogen-activated protein (MAP) kinase activation. (1993) (127)
- Androgen Receptor Phosphorylation REGULATION AND IDENTIFICATION OF THE PHOSPHORYLATION SITES* (2002) (120)
- Biochemical Analysis of MEK Activation in NIH3T3 Fibroblasts (1995) (117)
- Elevation of cyclic adenosine 3',5'-monophosphate potentiates activation of mitogen-activated protein kinase by growth factors in LNCaP prostate cancer cells. (1999) (114)
- Uridine transport and RNA synthesis in growing and in density‐inhibited animal cells (1971) (110)
- Comparative inactivation of viruses by chlorine (1980) (106)
- Src Phosphorylates the Insulin-like Growth Factor Type I Receptor on the Autophosphorylation Sites (1996) (105)
- Phosphate transport, nucleotide pools, and ribonucleic acid synthesis in growing and in density-inhibited 3T3 cells. (1971) (105)
- Autophosphorylation in vitro of recombinant 42-kilodalton mitogen-activated protein kinase on tyrosine. (1991) (103)
- Tyrosine phosphorylation of specific proteins after mitogen stimulation of chicken embryo fibroblasts (1983) (98)
- A diffusible factor responsible for the determination of cholinergic functions in cultured sympathetic neurons. Partial purification and characterization. (1981) (92)
- Inhibition of v-src-induced transformation by a GTPase-activating protein (1991) (90)
- p42/mitogen-activated protein kinase as a converging target for different growth factor signaling pathways: use of pertussis toxin as a discrimination factor. (1991) (89)
- The phorbol ester-dependent activator of the mitogen-activated protein kinase p42mapk is a kinase with specificity for the threonine and tyrosine regulatory sites. (1992) (83)
- Growth hormone and erythropoietin differentially activate DNA-binding proteins by tyrosine phosphorylation (1994) (83)
- Ribosomal RNA turnover in contact inhibited cells. (1972) (83)
- Regulation of tetradecanoyl phorbol acetate-induced responses in NIH 3T3 cells by GAP, the GTPase-activating protein associated with p21c-ras (1992) (79)
- Sequence of pp42/MAP kinase, a serine/threonine kinase regulated by tyrosine phosphorylation (1991) (77)
- Defective regulation of mitogen-activated protein kinase activity in a 3T3 cell variant mitogenically nonresponsive to tetradecanoyl phorbol acetate (1991) (77)
- A common FADS2 promoter polymorphism increases promoter activity and facilitates binding of transcription factor ELK1 (2010) (76)
- Differential tyrosine phosphorylation of JAK1, JAK2, and STAT1 by growth hormone and interferon-gamma in IM-9 cells. (1994) (76)
- Increased IκB kinase activity is associated with activated NF-κB in acute myeloid blasts (2002) (75)
- Partial purification of a mitogen-activated protein kinase kinase activator from bovine brain. Identification as B-Raf or a B-Raf-associated activity. (1994) (75)
- Regulation of enzymes responsible for neurotransmitter synthesis and degradation in cultured rat sympathetic neurons. I. Effects of muscle-conditioned medium. (1984) (74)
- An Incomplete Program of Cellular Tyrosine Phosphorylations Induced by Kinase-defective Epidermal Growth Factor Receptors (*) (1995) (74)
- Plasmin-activated prodrugs for cancer chemotherapy. 2. Synthesis and biological activity of peptidyl derivatives of doxorubicin. (1983) (74)
- A tumor promoter stimulates phosphorylation on tyrosine. (1983) (72)
- Biochemical characterization of a family of serine/threonine protein kinases regulated by tyrosine and serine/threonine phosphorylations. (1991) (70)
- Phosphorylation and activation of epidermal growth factor receptors in cells transformed by the src oncogene (1991) (68)
- Role for tyrosine phosphorylation and Lyn tyrosine kinase in fas receptor-mediated apoptosis in eosinophils. (1998) (67)
- Stimulation of tyrosine phosphorylation in human cells by activation of the growth hormone receptor. (1993) (66)
- c phosphorylation and activation of the IGF-I receptor in src-transformed cells. (1994) (65)
- Tumor necrosis factor alpha induces BID cleavage and bypasses antiapoptotic signals in prostate cancer LNCaP cells. (2001) (65)
- Growth factor-induced activation of a kinase activity which causes regulatory phosphorylation of p42/microtubule-associated protein kinase (1992) (65)
- Identification of Phosphotyrosine-Containing Proteins in Untransformed and Rous Sarcoma Virus-Transformed Chicken Embryo Fibroblasts (1982) (63)
- Degradation and biosynthesis of the glucose transporter protein in chicken embryo fibroblasts transformed by the src oncogene. (1987) (59)
- Protease-activated "prodrugs" for cancer chemotherapy. (1980) (58)
- Transformation by the src oncogene alters glucose transport into rat and chicken cells by different mechanisms (1988) (58)
- A TRANSAMIDASE MECHANISM FOR INSOLUBLE FIBRIN FORMATION. (1964) (57)
- Immune complex kinase assays for mitogen-activated protein kinase and MEK. (1995) (57)
- Identification of Tyr-185 as the site of tyrosine autophosphorylation of recombinant mitogen-activated protein kinase p42mapk. (1992) (56)
- Biological properties of "partial" transformation mutants of Rous sarcoma virus and characterization of their pp60src kinase (1981) (56)
- Photolabeling of glucose-sensitive cytochalasin B binding proteins in erythrocyte, fibroblast and adipocyte membranes. (1982) (56)
- Proteins antigenically related to the human erythrocyte glucose transporter in normal and Rous sarcoma virus-transformed chicken embryo fibroblasts. (1982) (54)
- Relationship between changes in the calcium dependent regulatory protein and adenylate cyclase during viral transformation. (1979) (53)
- The inhibition by chloramphenicol of nascent protein formation in E. coli. (1966) (52)
- Mutations in the SH3 domain of the src oncogene which decrease association of phosphatidylinositol 3'-kinase activity with pp60v-src and alter cellular morphology (1992) (51)
- Plasmin-activated prodrugs for cancer chemotherapy. 1. Synthesis and biological activity of peptidylacivicin and peptidylphenylenediamine mustard. (1983) (51)
- Constitutive phosphorylation of the receptor for insulinlike growth factor I in cells transformed by the src oncogene (1990) (51)
- Phosphotyrosine-containing proteins and expression of transformation parameters in cells infected with partial transformation mutants of Rous sarcoma virus (1983) (49)
- Fibroblasts transformed with v-src show enhanced formation of an inositol tetrakisphosphate. (1989) (49)
- The use of a tyrosine-hydroxylase cDNA probe to study the neurotransmitter plasticity of rat sympathetic neurons in culture. (1987) (49)
- Tyrosine Kinases Are Required for Catecholamine Secretion and Mitogen‐Activated Protein Kinase Activation in Bovine Adrenal Chromaffin Cells (1996) (47)
- Increased IkappaB kinase activity is associated with activated NF-kappaB in acute myeloid blasts. (2002) (47)
- Alterations in lipid acyl group composition and membrane structure in cells transformed by Rous sarcoma virus. (1976) (46)
- Comparison of the effects of elevated K+ ions and muscle-conditioned medium on the neurotransmitter phenotype of cultured sympathetic neurons. (1987) (45)
- Acetylcholine metabolism in rat spinal cord cultures: regulation by a factor involved in the determination of the neurotransmitter phenotype of sympathetic neurons (1984) (44)
- Modification of the lipid composition of normal and Rous sarcoma virus-infected cells. Effects on transformation-associated membrane properties. (1977) (38)
- Cell surface changes and Rous sarcoma virus gene expression in synchronized cells (1975) (38)
- Differential regulation of glucose transporter isoforms by the src oncogene in chicken embryo fibroblasts (1991) (38)
- Molecular Properties of a Cholinergic Differentiation Factor from Muscle‐Conditioned Medium (1985) (37)
- Phosphorylation of a 36,000 Mr cellular protein in cells infected with partial transformation mutants of rous sarcoma virus (1982) (36)
- Identification of a neuron-specific promoter of human aromatic L-amino acid decarboxylase gene. (1993) (33)
- Transport changes associated with growth control and malignant transformation (1976) (33)
- Tyrosine phosphorylation in cells treated with transforming growth factor‐β (1986) (32)
- Human growth hormone (GH) receptor is characterized as the 134-kilodalton tyrosine-phosphorylated protein activated by GH treatment in IM-9 cells. (1993) (31)
- Regulation of neurotransmitter metabolic enzymes and tyrosine hydroxylase mRNA level by nerve growth factor in cultured sympathetic neurones. (1988) (31)
- Mitogen‐stimulated tyrosine phosphorylation of a 42‐kD cellular protein: Evidence for a protein kinase‐C requirement (1988) (31)
- Tumorigenicity of partial transformation mutants of Rous sarcoma virus (1982) (30)
- Changes in acyl group composition of phospholipids from chicken embryonic fibroblasts after transformation by Rous sarcoma virus. (1972) (29)
- Comparison of three methods for detecting tyrosine-phosphorylated proteins. (1991) (27)
- Transport of potassium, amino acids, and glucose in cells transformed by Rous sarcoma virus. (1984) (27)
- SCH 51344 inhibits ras transformation by a novel mechanism. (1995) (27)
- Winged helix hepatocyte nuclear factor 3 and POU-domain protein brn-2/N-oct-3 bind overlapping sites on the neuronal promoter of human aromatic L-amino acid decarboxylase gene. (1998) (26)
- Activation of the MAP kinase cascade by histone deacetylase inhibitors is required for the stimulation of choline acetyltransferase gene promoter. (1998) (25)
- Protein phosphorylation in a tetradecanoyl phorbol acetate-nonproliferative variant of 3T3 cells (1985) (24)
- Oxidative stress induces tyrosine phosphorylation of PDGF alpha-and beta-receptors and pp60c-src in mesangial cells. (1996) (23)
- Calcium interactions in pulmonary surfactant. (1984) (22)
- Regulation of enzymes responsible for neurotransmitter synthesis and degradation in cultured rat sympathetic neurons. II. Regulation of 16 S acetylcholinesterase by conditioned medium. (1984) (22)
- Atrial Natriuretic Peptide Inhibits Mitogen-activated Protein Kinase through the Clearance Receptor POTENTIAL ROLE IN THE INHIBITION OF ASTROCYTE PROLIFERATION* (1996) (22)
- Influence of the culture substratum on the expression of choline acetyltransferase activity in purified motoneurons from rat embryos. (1989) (21)
- Acetylcholine metabolism by cultured neurons from rat nodose ganglia: regulation by a macromolecule from muscle-conditioned medium (1984) (21)
- Glycoprotein tyrosine phosphorylation in Rous sarcoma virus-transformed chicken embryo fibroblasts (1990) (21)
- Differential effects of lipopolysaccharide and tumor necrosis factor on monocytic IkappaB kinase signalsome activation and IkappaB proteolysis. (1999) (20)
- Characterization of the vesicular monoamine transporter in cultured rat sympathetic neurons: persistence upon induction of cholinergic phenotypic traits. (1987) (20)
- Down‐modulation of EGF receptors in cells transformed by the src oncogene (1987) (20)
- Induction of the vesicular monoamine transporter by elevated potassium concentration in cultures of rat sympathetic neurons. (1990) (19)
- Amino acid transport in normal and Rous sarcoma virus‐transformed chicken embryo fibroblasts (1979) (19)
- Inhibition of the Peptide Bond Synthesizing Cycle by Chloramphenicol (1969) (19)
- The role of Ca2+ channels of the L-type in neurotransmitter plasticity of cultured sympathetic neurons. (1989) (19)
- Identification of sites on epidermal growth factor receptors which are phosphorylated by pp60src in vitro. (1996) (18)
- Multiple pathways for activation of MAP kinases. (1993) (18)
- Potassium fluxes and ouabain binding in growing, density‐inhibited and rous sarcoma virus‐transformed chicken embryo cells (1979) (17)
- Effect of membrane phospholipid composition changes on adenylate cyclase activity in normal and rous-sarcoma-transformed chicken embryo fibroblasts. (1980) (17)
- Regulation of enzymes responsible for neurotransmitter synthesis and degradation in cultured rat sympathetic neurons. III. Effects of sodium butyrate. (1984) (17)
- The src oncogene can regulate a human glucose transporter expressed in chicken embryo fibroblasts (1990) (17)
- Scaffold protein regulation of mitogen-activated protein kinase cascade. (2001) (16)
- NF-Y binding is required for transactivation of neuronal aromatic L-amino acid decarboxylase gene promoter by the POU-domain protein Brn-2. (2001) (16)
- Neuronal promoter of human aromatic L-amino acid decarboxylase gene directs transgene expression to the adult floor plate and aminergic nuclei induced by the isthmus. (2001) (16)
- Inhibition of epidermal growth factor receptor biosynthesis caused by the src oncogene product, pp60v-src (1990) (16)
- A Swiss 3T3 variant cell line resistant to the effects of tumor promoters cannot be transformed by src (1990) (16)
- Increased membrane transport of 2‐deoxyglucose and 3‐0‐methylglucose is an early event in the transformation of chick embryo fibroblasts by rous sarcoma virus (1978) (15)
- Serum stimulation of potassium fluxes, ouabain binding, and sodium fluxes in quiescent chicken embryo fibroblasts (1980) (14)
- [Acne, hyperandrogenism and oral isotretinoin resistance. 23 cases. Therapeutic implications]. (1997) (13)
- Multiple promoters of human choline acetyltransferase and aromatic L-amino acid decarboxylase genes (1994) (13)
- Histone hyperacetylating agents stimulate promoter activity of human choline acetyltransferase gene in transfection experiment. (1996) (13)
- The interaction of phosphate with the purple acid phosphatase from beef spleen: evidence that phosphate binding is accompanied by oxidation of the iron chromophore. (1986) (12)
- Phenotypic variation and associated predation risk of juvenile common carp Cyprinus carpio. (2012) (12)
- Glucose-specific cytochalasin B binding is increased in chicken embryo fibroblasts transformed by Rous sarcoma virus. (1979) (11)
- Immunostaining for activated extracellular signal-regulated kinases in cells and tissues. (2001) (10)
- Solubilization of adenylate cyclase from normal and Rous sarcoma-transformed chicken embryo fibroblasts. (1976) (10)
- Phosphorylation of protein kinase C by casein kinase‐1 (1989) (10)
- Turnover of cellular carbohydrates in normal and Rous sarcoma virus-transformed cells. (1978) (10)
- The 3′ portion of the mouse H19 Imprinting-Control Region is required for proper tissue-specific expression of the Igf2 gene (2006) (9)
- A common FADS 2 promoter polymorphism increases promoter activity and facilitates binding of transcription factor ELK 1 (2009) (9)
- Treatment of systemic candidiasis in neutropenic dogs with ketoconazole. (1985) (7)
- Functional expression in mammalian cells of a full‐length cDNA coding for the pp42/MAP kinase (p42 mapk ) protein (1991) (6)
- [Acne caused by Survector]. (1988) (6)
- Molecular events leading to enhanced glucose transport in Rous sarcoma virus-transformed cells. (1984) (5)
- A comparison between adenylate cyclase solubilized from normal and Rous sarcoma virus-transformed chicken embryo fibroblasts. (1980) (5)
- Membrane lipid acyl group alterations in cells infected with a temperature-conditional mutant of Rous sarcoma virus. (1976) (5)
- Progress in the purification of a factor involved in the neurotransmitter choice made by cultured sympathetic neurons. (1982) (5)
- Degradation and biosynthesis of the glucose transporter protein in chicken embryo fibroblasts transformed by the src oncogene (1987) (4)
- Apparent sufficiency of a dual-specificity tyrosine/threonine kinase for activation of MAP kinase poses new questions for the dual-phosphorylation mechanism. (1992) (4)
- Phosphorylation and activation of p40 tyrosine kinase by casein kinase‐1 (1990) (3)
- A peptidyl derivative of [3H]aniline as a sensitive, stable, protease substrate. (1979) (3)
- Lack of correlation between pp60src kinase activity and transformation parameters in cells infected with temperature-conditional mutants of Rous sarcoma virus. (1981) (3)
- Genetic and biochemical approaches to analyzing transformation by Rous sarcoma virus. (1980) (2)
- Metabolic and Transport Alterations in Cells Transformed by Rous Sarcoma Virus (1984) (2)
- Regulation of neurotransmitter synthesis: from neuron to gene. (1991) (1)
- The role of extracellular signals in the differentiation of cholinergic neurons from the CNS and PNS in culture. (1985) (1)
- 30 Regulation of human choline acetyltransferase gene by inhibitors of histone deacetylase (1998) (1)
- Cultured cells transformed by Rous sarcoma virus: a genetically defined model and its phenotype. (1983) (0)
- sarcoma virus. transformation mutants of Rous Tumorigenicity of partial (2013) (0)
- Effect of growth conditions on the content of the major groups of carbohydrates in chick embryo fibroblasts. (1979) (0)
- Inhibition of Epidermal Growth Factor Receptor Biosynthesis (2003) (0)
- PLASMIN‐ACTIVATED ANTICANCER PRODRUGS (1982) (0)
- on tyrosine phosphorylation . Ras-induced activation of Raf-1 is dependent (1996) (0)
- Stimulation of Chicken Embryo Fibroblasts (0)
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