Malcolm L. Gefter
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Malcolm L. Gefterbiology Degrees
Biology
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Molecular Biology
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#1133
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Biology
Why Is Malcolm L. Gefter Influential?
(Suggest an Edit or Addition)Malcolm L. Gefter's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- DNA replication. (1975) (1471)
- DNA-dependent transcription of adenovirus genes in a soluble whole-cell extract. (1980) (839)
- A simple method for polyethylene glycol-promoted hybridization of mouse myeloma cells (1977) (566)
- Properties and applications of monoclonal antibodies directed against determinants of the Thy-1 locus. (1979) (544)
- Design, synthesis and selection of DNA-encoded small-molecule libraries. (2009) (428)
- Role modifications in tyrosine transfer RNA: a modified base affecting ribosome binding. (1969) (328)
- A DNA-unwinding protein isolated from Escherichia coli: its interaction with DNA and with DNA polymerases. (1972) (257)
- Immunological self, nonself discrimination. (1987) (233)
- Efficacy of a therapeutic cocaine vaccine in rodent models (1996) (225)
- Analysis of DNA polymerases II and 3 in mutants of Escherichia coli thermosensitive for DNA synthesis. (1971) (217)
- Somatic evolution of variable region structures during an immune response. (1986) (206)
- Interactions between Immunogenic Peptides and MHC Proteins (1991) (200)
- Methylation of DNA (1966) (200)
- Interaction of peptide antigens and class II major histocompatibility complex antigens (1986) (198)
- Base substitution in an intervening sequence of a beta+-thalassemic human globin gene. (1981) (195)
- Duplicate genes for tyrosine transfer RNA in Escherichia coli. (1970) (188)
- Structure and in vitro transcription of human globin genes. (1980) (182)
- Role of γ-interferon in antibody-producing responses (1984) (178)
- Enzyme-catalyzed DNA unwinding: studies on Escherichia coli rep protein. (1979) (158)
- Purification and DNA synthesis in cell-free extracts: properties of DNA polymerase II. (1971) (152)
- Evolution of Antibody Variable Region Structure during the Immune Response (1987) (143)
- The genetic basis of antibody production: A single heavy chain variable region gene encodes all molecules bearing the dominant anti‐arsonate idiotype in the strain A mouse (1983) (135)
- Interactions between immunogenic peptides and MHC proteins. (1991) (130)
- Effect of IFN-γ on the immune response in vivo and on gene expression in vitro (1984) (130)
- Preferential autoantibody reactivity of the preimmune B cell repertoire in normal mice. (1988) (117)
- The enzymatic methylation of ribonucleic acid and deoxyribonucleic acid. X. Bacteriophage T3-induced S-adenosylmethionine cleavage. (1966) (106)
- Mutant tyrosine transfer ribonucleic acids. (1970) (99)
- Immunological activity of covalently linked T-cell epitopes (1990) (97)
- Properties of the Escherichia coli DNA-binding (unwinding) protein interaction with nucleolytic enzymes and DNA. (1975) (96)
- The molecular evolution of the immune response. (1985) (96)
- Deoxyribonucleic acid synthesis in cell-free extracts. IV. Purification and catalytic properties of deoxyribonucleic acid polymerase III. (1972) (94)
- Characterization of the gamma-interferon-mediated induction of antigen-presenting ability in P388D1 cells. (1983) (93)
- Gene conversion and the generation of antibody diversity. (1989) (89)
- The genetic basis of antibody production: The dominant anti‐arsonate idiotype response of the strain a mouse (1982) (89)
- The enzymatic repair of DNA. I. Formation of circular lambda-DNA. (1967) (87)
- DNA synthesis in cell-free extracts of a DNA polymerase-defective mutant. (1970) (86)
- Murine MHC polymorphism and T cell specificities. (1989) (82)
- Pertussis toxin prevents the induction of peripheral T cell anergy and enhances the T cell response to an encephalitogenic peptide of myelin basic protein. (1991) (80)
- Immunodominance: intramolecular competition between T cell epitopes. (1991) (80)
- Purification and properties of the Escherichia coli deoxyribonucleic acid-unwinding protein. Effects on deoxyribonucleic acid synthesis in vitro. (1974) (75)
- An iron-dependent modification of several transfer RNA species in Escherichia coli. (1969) (73)
- T lymphocyte response to bacteriophage lambda repressor cI protein. Recognition of the same peptide presented by Ia molecules of different haplotypes. (1987) (72)
- Single germline VH and V kappa genes encode predominating antibody variable regions elicited in strain A mice by immunization with p- azophenylarsonate (1987) (72)
- Restricted V-(D)-J junctional regions in the T cell response to lambda-repressor. Identification of residues critical for antigen recognition. (1990) (72)
- Physical studies of the interaction between the Escherichia coli DNA binding protein and nucleic acids. (1975) (70)
- RNA synthesis in isolated nuclei: in vitro initiation of adenovirus 2 major late mRNA precursor. (1979) (70)
- Peripheral tolerance in T cell receptor‐transgenic mice: Evidence for T cell anergy (1996) (69)
- The enzymatic repair of DNA, II. Characterization of phage-induced sealase. (1967) (65)
- Identical peptides recognized by MHC class I- and II-restricted T cells (1989) (64)
- Bacteriophage φ80-induced low molecular weight RNA (1972) (62)
- Studies on the mechanism of enzymatic DNA elongation by Escherichia coli DNA polymerase II. (1976) (61)
- Properties of the Escherichia coli in DNA binding (unwinding) protein: interaction with DNA polymerase and DNA. (1974) (59)
- Dual expression of λ genes in the MOPC-315 plasmacytoma (1981) (58)
- Transcription of Simian virus 40 DNA in a HeLa whole cell extract. (1981) (58)
- Cytolytic activity of antigen-specific T cells with helper phenotype. (1986) (53)
- A mutant of Escherichia coli defective in DNA polymerase II activity. (1972) (52)
- Immunotherapy with T‐cell‐reactive peptides derived from allergens (1994) (51)
- Isolation of hybridomas expressing a specific heavy chain variable region gene segment by using a screening technique that detects mRNA sequences in whole cell lysates. (1984) (51)
- The molecular evolution of the immune response: idiotope‐specific suppression indicates that B cells express germ‐line‐encoded V genes prior to antigenic stimulation (1986) (50)
- RNA synthesis in isolated nuclei: identification and comparison of adenovirus 2 encoded transcripts synthesized in vitro and vivo. (1979) (47)
- A DNA-binding protein induced by bacteriophage T7. (1973) (46)
- T cell receptor gene usage in the response to lambda repressor cI protein. An apparent bias in the usage of a V alpha gene element (1988) (46)
- Regulation of immunoglobulin expression in mouse myeloma cells. (1977) (45)
- Rna synthesis in isolated nuclei processing of adenovirus serotype 2 late messenger rna precursors. (1982) (44)
- Expression of a VHCκ chimaeric protein in mouse myeloma cells (1984) (44)
- Site-directed mutagenesis of an invariant amino acid residue at the variable-diversity segments junction of an antibody. (1986) (40)
- T lymphocyte-mediated suppression of myeloma function in vitro. III. Regulation of antibody production in hybrid myeloma cells by T lymphocytes (1979) (40)
- Δ2-Isopentenylpyrophosphate: Transfer Ribonucleic Acid Δ2-Isopentenyltransferase from Escherichia coli PURIFICATION AND PROPERTIES OF THE ENZYME (1972) (38)
- Control of immunoglobulin secretion in the murine plasmacytoma line MOPC 315 (1978) (38)
- Deoxyribonucleic acid synthesis in cell-free extracts. 3. Catalytic properties of deoxyribonucleic acid polymerase II. (1972) (37)
- A deoxyribonucleic acid-binding protein induced by bacteriophage T7. Purification and properties of the protein. (1974) (36)
- In vitro synthesis of transfer RNA. II. Identification of required enzymatic activities. (1975) (36)
- The in vitro synthesis of 2′-omethylguanosine and 2-methylthio 6N (γ,γ, dimethylallyl) adenosine in transfer RNA of Escherichia coli (1969) (34)
- In vitro synthesis of transfer RNA. I. Purification of required components. (1975) (30)
- Immunodominance: intermolecular competition between MHC class II molecules by covalently linked T cell epitopes. (1992) (29)
- Synthesis of messenger RNA-like molecules in isolated myeloma nuclei. (1977) (29)
- Unique determinants associated with hybridoma proteins expressing a cross-reactive idiotype: frequency among individual immune sera. (1980) (28)
- Monoclonal antibodies to Rhizobium meliloti and surface mutants insensitive to them (1984) (27)
- Enzyme-catalyzed DNA unwinding. Mechanism of action of helicase III. (1979) (27)
- DNA Polymerases II and III of Escherichia coli (1974) (26)
- Role of gamma-interferon in antibody-producing responses. (1984) (26)
- Enzymatic reactions at termini of DNA (1967) (25)
- Shared idiotopes among antibodies encoded by heavy-chain variable region (VH) gene members of the J558 VH family as basis for cross-reactive regulation of clones with different antigen specificity. (1985) (24)
- Adenosine diphosphate-dependent threonine dehydrase activity in extracts of Clostridium tetanomorphum. (1963) (23)
- Silencing of immunodominant epitopes by contiguous sequences in complex synthetic peptides. (1992) (23)
- The rep protein of Escherichia coli: interaction with DNA and other proteins. (1979) (23)
- The generation of major and minor idiotype-bearing families of anti-p-azophenylarsonate antibodies; stochastic utilization of VH gene segments. (1985) (23)
- Analysis of DNA Polymerases II and III in Mutants of Escherichia coli (22)
- DNA-directed cell-free synthesis of biologically active transfer RNA: su + 3 tyrosyl-tRNA. (1971) (22)
- Structural Correlates of Idiotypy in the Arsonate System a (1983) (22)
- Identification of mutant monoclonal antibodies with increased antigen binding. (1988) (22)
- Role of modifications in tyrosine transfer RNA. II. Ribothymidylate-deficient tRNA. (1973) (22)
- Combinational diversity within variable regions bearing the predominant anti-p-azophenylarsonate idiotype of strain A mice. (1985) (21)
- Crystal structure of the antigen-binding fragment of the murine anti-arsonate monoclonal antibody 36-71 at 2.9-A resolution. (1990) (19)
- Multiple expression of Ig lambda-chain encoding RNA species in murine plasmacytoma cells. (1981) (17)
- Mutant tyrosine transfer ribonucleic acids (1969) (16)
- Peptide therapy for treatment of allergic diseases. (1996) (16)
- Enzyme-catalyzed DNA unwinding. A DNA-dependent ATPase from E. coli. (1979) (16)
- Effect of IFN-gamma on the immune response in vivo and on gene expression in vitro. (1984) (16)
- RNA synthesis in isolated nuclei: the use of mercurated nucleotides. (1978) (15)
- Down-regulation of poison ivy/oak-induced contact sensitivity by treatment with a class II MHC binding peptide:hapten conjugate. (1997) (15)
- Molecular limitations on variable-gene junctional diversity. (1986) (15)
- New Method for Large-Scale Preparation of Covalently Closed λ DNA Molecules (1974) (14)
- REGULATION OF ADENOVIRUS mRNA SYNTHESIS * (1980) (12)
- Transcription of immunoglobulin heavy-chain sequences from the excluded allele (1981) (12)
- Control of cellular and humoral immune responses by peptides containing T-cell epitopes. (1989) (11)
- Transcription of mammalian genes in vitro. (1981) (11)
- THE ENZYMATIC REPAIR OF DNA, I. FORMATION OF CIRCULAR XDNA* (10)
- Analysis of the anti-azobenzenearsonate response at the molecular level. (1984) (10)
- Functional and biochemical characterization of a secreted I-J(+) suppressor factor that binds to immunoglobulin (1986) (10)
- Regulation of immunoglobulin biosynthesis in the murine plasmacytoma MOPC 315. (1978) (10)
- Immunology: Development and modification of the lymphocyte repertoire (1986) (10)
- The Role of Deoxyribonucleic Acid in Ribonucleic Acid Synthesis X. THE INFLUENCE OF 6-METHYLAMINOPURINE ON NUCLEIC ACID SYNTHESIS IN VITRO (1966) (10)
- The purification of exonuclease I from Escherichia coli by affinity chromatography. (1974) (9)
- Expression of a VHC kappa chimaeric protein in mouse myeloma cells. (1984) (8)
- Studies on synthesis and modification of transfer RNA. (1971) (7)
- Delta 2 -isopentenylpyrophosphate: transfer ribonucleic acid 2 -isopentenyltransferase from Escherichia coli. Purification and properties of the enzyme. (1972) (6)
- The in vitro synthesis of 2'-omethylguanosine and 2-methylthio 6N (gamma,gamma, dimethylallyl) adenosine in transfer RNA of Escherichia coli. (1969) (5)
- Erratum: Design, synthesis and selection of DNA-encoded small-molecule libraries (2009) (5)
- Enzyme-catalyzed DNA unwinding. The role of ATP in helicase III activity. (1980) (5)
- "Distinguishable steps in the enzymatic synthesis of bacteriophage phiX174 replicative form in vitro". (1976) (5)
- [3] Deoxyribonucleic acid polymerase III (Escherichia coli K12) (1974) (5)
- Cell-free synthesis of SU + 3 tyrosyl transfer RNA: characterization of the 4S product. (1973) (5)
- Genetic recombination in the α2 domain of the Eα chain yields an Ed molecule with altered T cell activation (1990) (3)
- Crossing-over frequency in the Igh region of the mouse genome. (1984) (3)
- In Vitro Synthesis of Transfer RNA (2002) (3)
- 20 DNA Unwinding Enzymes (1981) (3)
- Deoxyribonucleic acid polymerase 3 (Escherichia coli K12). (1974) (3)
- Studies on DNA Polymerases II and III of Escherichia coli (1973) (2)
- Structure andinvitro Transcription ofHumanGlobin Genes (1980) (2)
- The role of antigen-driven selection in the expression and control of idiotypes. (1984) (2)
- T CELL RECEPTOR GENE USAGE IN THE RESPONSE TO X REPRESSOR cI PROTEIN An Apparent Bias in the Usage of a Va Gene Element (2003) (2)
- Dual expression of lambda genes in the MOPC-315 plasmacytoma. (1981) (2)
- Cellular immunology : selected readings and critical commentary (1981) (1)
- Bacteriophage phi 80-induced low molecular weight RNA. (1972) (1)
- The molecular basis of a VH gene polymorphism that determines the expression of a major idiotype. (1989) (1)
- Escherichia coli DNA Polymerases II and III (1974) (1)
- 815 Intravenous administration of a potential T cell toleragenic peptide to cat sensitive patients (1996) (1)
- New method for large-scale preparation of covalently closed lambda DNA molecules. (1974) (0)
- Isolation of hybridomas expressing region gene segment by using a sci mRNA sequences in whole cell lysa (monoclonal antibodies/filter hybridization/bacterial lipopolysacchar (2016) (0)
- Immunomodulating agents and the use of these (1988) (0)
- INVITRO SYNTHESIS OF BIOLOGICALLY-ACTIVE TRANSFER-RNA - IDENTIFICATION OF 3' END MATURATION ENZYME (1975) (0)
- Hapten carrier conjugates for use in drug addiction therapy and methods for producing same (1997) (0)
- Pharmaceutical formulations comprising a vanduoplöseligt complex for sustained delivery of the drug substance (1997) (0)
- Haptan-carrier conjugates for employment in therapy against drug use (1996) (0)
- DNA polymerases II and 3 of Escherichia coli. (1974) (0)
- [193] T3 and UV-T3-induced S-adenosylmethionine cleavage enzyme (Escherichia coli) (1971) (0)
- NUCLEIC ACIDS (1973) (0)
- The dnaG Gene Product of Escherichia Coli: Characterization of the Catalytic Activity (1978) (0)
- Modulators of beta-amyloidpeptidaggregering comprising D-amino acids (1997) (0)
- the same peptide presented by Ia molecules of lambda repressor cI protein . Recognition of T lymphocyte response to bacteriophage (2001) (0)
- A pharmaceutical sustained release compositions containing the water-insoluble complex compounds (1997) (0)
- Immunomodulare medium and its use. (1987) (0)
- Genetic recombination in the alpha 2 domain of the E alpha chain yields an Ed molecule with altered T cell activation. (1990) (0)
- Hapten-carrier conjugates for use in drug therapy and methods for their preparation (1997) (0)
- Methods for the treatment of prostate cancer with LHRH antagonists (1996) (0)
- NewMethodforLarge-Scale Preparation ofCovalently Closed XDNA Molecules (1974) (0)
- SYNTHESIS AND PROCESSING OF ADENOVIRUS 2 RNA IN VITRO (1979) (0)
- Hapten-carrier conjugates for use in drug abuse treatment (1996) (0)
- Pharmaceutical formulations for sustained drug release. (1997) (0)
- TRANSCRIPTION OF ANIMAL VIRUS GENES IN VITRO1 (1980) (0)
- Hapten-carrier conjugates for use in drug addiction therapy and methods for the preparation thereof. (1997) (0)
- Compositions pharmaceutiques pour medicaments a liberation prolongee (2001) (0)
- SYNTHESIS OF ADENOVIRUS 2 RNA in vitro: PROPERTIES OF THE MAJOR LATER TRANSCRIPT AND ITS PROMOTER (1980) (0)
- Antigen Specific Peptides: Role in Immunomodulation (1997) (0)
- Hapten-carrier conjugates for use in the treatment of substance abuse (1996) (0)
- Topologically engineered antibodies and Fc-fusion proteins: a new class of multifunctional therapeutic candidates for SARS-CoV-2, cancer, and other disease (2022) (0)
- Method of identifying compounds that bind to a biological target molecule (2006) (0)
- 1 Antigen Specific Immunotherapy for Allergic Disease (1994) (0)
- A SINGLE GERMLINE VF, GENE SEGMENT OF NORMAL A/J MICE ENCODES AUTOANTIBODIES CHARACTERISTIC OF SYSTEMIC LUPUS ERYTHEMATOSUS (2003) (0)
- AN ADP DEPENDENT THREONINE DEHYDRASE FROM CLOSTRIDIUM TETANOMORPHUM (1963) (0)
- Therapeutic agents and methods of their use for the treatment of amyloidogenic illnesses (2001) (0)
- Properties of the Escherichia coli DNA Binding Interaction with DNA Polymerase and DNA (Unwinding) Protein: (0)
- contain pharmaceutical sustained release composition, the water-insoluble complex compounds (1997) (0)
- X-ray crystallography of FAB fragments of anti-digoxin and anti-arsonate antibodies (1984) (0)
- Compositions for multiple sclerosis and its treatment (1997) (0)
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