Margaret Loewy Kirby
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Developmental Biology
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Biology
Margaret Loewy Kirby's Degrees
- PhD Developmental Biology Stanford University
- Bachelors Biology University of California, Berkeley
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(Suggest an Edit or Addition)Margaret Loewy Kirby's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Neural crest cells contribute to normal aorticopulmonary septation. (1983) (1081)
- Regulation of cardiac mesodermal and neural crest development by the bHLH transcription factor, dHAND (1997) (715)
- Conotruncal myocardium arises from a secondary heart field. (2001) (648)
- Neural crest and cardiovascular patterning. (1995) (552)
- Dependence of thymus development on derivatives of the neural crest. (1984) (472)
- Role of Neural Crest in Congenital Heart Disease (1990) (381)
- Secondary heart field contributes myocardium and smooth muscle to the arterial pole of the developing heart. (2005) (332)
- Characterization of conotruncal malformations following ablation of “cardiac” neural crest (1985) (289)
- Neural crest and cardiovascular development: a 20-year perspective. (2003) (289)
- Model systems for the study of heart development and disease. Cardiac neural crest and conotruncal malformations. (2007) (288)
- Role of cardiac neural crest cells in cardiovascular development. (1998) (281)
- Cardiac neural crest cells provide new insight into septation of the cardiac outflow tract: aortic sac to ventricular septal closure. (1998) (278)
- Myocardial lineage development. (2010) (272)
- Heart field: from mesoderm to heart tube. (2007) (247)
- Gap Junction–mediated Cell–Cell Communication Modulates Mouse Neural Crest Migration (1998) (246)
- The role of secondary heart field in cardiac development. (2009) (237)
- Pathogenesis of persistent truncus arteriosus and dextroposed aorta in the chick embryo after neural crest ablation. (1987) (222)
- A Caudal Proliferating Growth Center Contributes to Both Poles of the Forming Heart Tube (2009) (186)
- Optical Coherence Tomography: A New High-Resolution Imaging Technology to Study Cardiac Development in Chick Embryos (2002) (180)
- Neural crest origin of cardiac ganglion cells in the chick embryo: identification and extirpation. (1983) (175)
- Double-stranded RNA injection produces null phenotypes in zebrafish. (2000) (173)
- Connexin 43 expression reflects neural crest patterns during cardiovascular development. (1999) (170)
- Effect of neural crest ablation on development of the heart and arch arteries in the chick. (1987) (169)
- Cardiac neural crest is necessary for normal addition of the myocardium to the arterial pole from the secondary heart field. (2005) (166)
- Ablation of the secondary heart field leads to tetralogy of Fallot and pulmonary atresia. (2005) (164)
- Cardiac Morphogenesis—Recent Research Advances (1987) (163)
- Cardiac neural crest is essential for the persistence rather than the formation of an arch artery (1996) (156)
- Shortened Outflow Tract Leads to Altered Cardiac Looping After Neural Crest Ablation (2002) (154)
- Neural crest and normal development: A new perspective (1984) (151)
- Heart fields: one, two or more? (2004) (139)
- Development of a lethal congenital heart defect in the splotch (Pax3) mutant mouse. (1997) (138)
- An essential role for connexin43 gap junctions in mouse coronary artery development. (2002) (134)
- Zebrafish cardiac development requires a conserved secondary heart field (2011) (133)
- Sonic hedgehog maintains proliferation in secondary heart field progenitors and is required for normal arterial pole formation. (2009) (129)
- Origin of the proximal coronary artery stems and a review of ventricular vascularization in the chick embryo. (1990) (129)
- Epicardium and Myocardium Separate From a Common Precursor Pool by Crosstalk Between Bone Morphogenetic Protein– and Fibroblast Growth Factor–Signaling Pathways (2009) (126)
- Initial migration and distribution of the cardiac neural crest in the avian embryo: an introduction to the concept of the circumpharyngeal crest. (1991) (124)
- Alteration of early vascular development after ablation of cranial neural crest (1989) (121)
- Factors controlling cardiac neural crest cell migration (2010) (119)
- Cardiac neural crest in zebrafish embryos contributes to myocardial cell lineage and early heart function (2003) (116)
- Plasticity and predetermination of mesencephalic and trunk neural crest transplanted into the region of the cardiac neural crest. (1989) (116)
- Effects of the size of lesions of the cardiac neural crest at various embryonic ages on incidence and type of cardiac defects. (1986) (111)
- ENU induced mutations causing congenital cardiovascular anomalies (2004) (105)
- Association of the cardiac neural crest with development of the coronary arteries in the chick embryo (1994) (105)
- Analysis of cranial neural crest distribution in the developing heart using quail-chick chimeras. (1987) (103)
- Cellular and molecular contributions of the cardiac neural crest to cardiovascular development. (1993) (102)
- Cardiac compartment-specific overexpression of a modified retinoic acid receptor produces dilated cardiomyopathy and congestive heart failure in transgenic mice. (1997) (101)
- Induction of Purkinje fiber differentiation by coronary arterialization. (1999) (97)
- Wherefore heart thou? Embryonic origins of cardiogenic mesoderm (2002) (93)
- HIRA, a DiGeorge syndrome candidate gene, is required for cardiac outflow tract septation. (1999) (92)
- A novel role for cardiac neural crest in heart development. (1999) (92)
- Solving an enigma: arterial pole development in the zebrafish heart. (2006) (91)
- Patterning of the heart field in the chick. (2008) (90)
- Cardiac arterial pole alignment is sensitive to FGF8 signaling in the pharynx. (2006) (88)
- ß-Arrestin 2 Regulates Zebrafish Development Through the Hedgehog Signaling Pathway (2004) (88)
- Temporospatial study of the migration and distribution of cardiac neural crest in quail-chick chimeras. (1991) (86)
- Increase in substance P in the dorsal horn during a chemogenic nociceptive stimulus (1985) (86)
- FGF8 signaling is chemotactic for cardiac neural crest cells. (2011) (84)
- Cardiac neural crest contribution to the pulmonary artery and sixth aortic arch artery complex in chick embryos aged 6 to 18 days (1993) (84)
- Neural crest is involved in development of abnormal myocardial function. (1997) (84)
- Gap junction communication and the modulation of cardiac neural crest cells. (1999) (82)
- Ablation of various regions within the avian vagal neural crest has differential effects on ganglion formation in the fore‐, mid‐ and hindgut (1993) (82)
- Arterial pole progenitors interpret opposing FGF/BMP signals to proliferate or differentiate (2010) (81)
- Molecular Embryogenesis of the Heart (2002) (81)
- A novel role for cardiac neural crest in heart development. (1999) (81)
- Origin and propagation of elastogenesis in the developing cardiovascular system (1988) (79)
- Endogenous retinoic acid signaling colocalizes with advanced expression of the adult smooth muscle myosin heavy chain isoform during development of the ductus arteriosus. (1996) (76)
- PCB126 exposure disrupts zebrafish ventricular and branchial but not early neural crest development. (2008) (75)
- Abnormal patterning of the aortic arch arteries does not evoke cardiac malformations (1997) (75)
- Connexin43 deficiency causes dysregulation of coronary vasculogenesis. (2005) (74)
- A correlative histofluorescence and light microscopic study of the formation of the sympathetic trunks in chick embryos (1976) (70)
- Migration of Cardiac Neural Crest Cells (1990) (68)
- Cardiac neural crest ablation inhibits compaction and electrical function of conduction system bundles. (2007) (65)
- Hensen's node gives rise to the ventral midline of the foregut: implications for organizing head and heart development. (2003) (64)
- Migration and distribution of circumpharyngeal crest cells in the chick embryo (1992) (64)
- Stereotaxic electrode placement in the neonatal rat (1979) (62)
- Calcium influx through L-type CaV1.2 Ca2+ channels regulates mandibular development. (2013) (61)
- Contribution of Neural Crest to Heart and Vessel Morphology (1999) (58)
- The outflow tract of the heart in fishes: anatomy, genes and evolution. (2009) (57)
- FGF-8 in the ventral pharynx alters development of myocardial calcium transients after neural crest ablation. (2001) (56)
- Developing innervation of the chick heart: A histofluorescence and light microscopic study of sympathetic innervation (1980) (55)
- Microcinephotography of the developing heart in neural crest-ablated chick embryos. (1990) (54)
- Backtransplantation of chick cardiac neural crest cells cultured in LIF rescues heart development (1993) (52)
- Hemodynamic Changes in Chick Embryos Precede Heart Defects After Cardiac Neural Crest Ablation (1986) (51)
- Development of adrenergic innervation of the iris and fluorescent ganglion cells in the choroid of the chick eye (1978) (49)
- Relation of Early Hemodynamic Changes to Final Cardiac Phenotpe and Survival After Neural Crest Ablation in Chick Embryos (1991) (48)
- Myocardial volume and organization are changed by failure of addition of secondary heart field myocardium to the cardiac outflow tract (2003) (43)
- Fallen arches, or how the vertebrate got its head. (1998) (41)
- Regulatory mechanisms for subtance P in the dorsal horn during a nociceptive stimulus: Axoplasmic transport vs electrical activity (1986) (41)
- Signals controlling neural crest contributions to the heart (2009) (40)
- Patterning of coronary arteries in wildtype and connexin43 knockout mice (2006) (40)
- Hemodynamic Changes and Compensatory Mechanisms during Early Cardiogenesis after Neural Crest Ablation in Chick Embryos (1991) (39)
- Coordinated and conserved expression of alphoid repeat and alphoid repeat‐tagged coding sequences (2003) (39)
- Tbx2 Represses Expression of Connexin43 in Osteoblastic-like Cells (2004) (38)
- Changes in Cholinergic Parameters Associated with Failure of Conotruncal Septation in Embryonic Chick Hearts after Neural Crest Ablation (1985) (36)
- Development of opiate receptor binding in rat spinal cord (1981) (33)
- Follistatin in chondrocytes: the link between TRPV4 channelopathies and skeletal malformations (2014) (33)
- Solitary aortic arch artery. A result of surgical ablation of cardiac neural crest and nodose placode in the avian embryo. (1989) (33)
- Improved preparation of chick embryonic samples for magnetic resonance microscopy (2003) (31)
- An ultrastructural study of the cardia ganglia in the bulbar plexus of the developing chick heart. (1980) (30)
- Adrenergic innervation of the developing chick heart: neural crest ablations to produce sympathetically aneural hearts. (1984) (30)
- BMP signaling modulates hedgehog-induced secondary heart field proliferation. (2010) (30)
- Absence of neural crest cell regeneration from the postotic neural tube. (1997) (30)
- Development of the Great Arteries (1998) (28)
- Histamine-induced relaxation of rat aorta. Importance of H1 receptor and vascular endothelium. (1984) (27)
- Neural crest interactions in the development of the immune system. (1985) (27)
- Cell biology of cardiac development. (2001) (27)
- Effects of morphine on spontaneous activity of 18-day rat fetus. (1979) (26)
- Neural crest ablation does not alter pulmonary vein development in the chick embryo (1989) (24)
- Levorphanol-sensitive [3H]naloxone binding in developing brainstem following prenatal morphine exposure (1983) (24)
- Embryogenesis of transposition of the great arteries: a lesson from the heart. (2002) (24)
- Cardiovascular Defects among the Progeny of Mouse Phenylketonuria Females (1997) (24)
- Embryonic origins of defective heart development. (1990) (23)
- Altered Development of Pharyngeal Arch Vessels after Neural Crest Ablation a (1990) (23)
- Developmental changes in serotonin and 5-hydroxyindoleacetic acid concentrations and opiate receptor binding in rat spinal cord following neonatal 5,7-dihydroxytryptamine treatment. (1982) (23)
- Effects of morphine and naloxone on spontaneous activity of fetal rats (1981) (22)
- Development of cranial nerves in the chick embryo with special reference to the alterations of cardiac branches after ablation of the cardiac neural crest (2004) (21)
- Atropine-induced alterations of normal development of muscarinic receptors in the embryonic chick heart. (1983) (21)
- Alteration of Cardiogenesis after Neural Crest Ablation a (1990) (21)
- Effects of chronic opiate administration on spontaneous activity of fetal rats (1982) (19)
- Changes in acid phosphatase activity in the substantia gelatinosa in response to pain (1982) (19)
- Regulation of beta-adrenergic receptor density in the non-innervated and denervated embryonic chick heart. (1986) (18)
- The cardiac ganglia: cellular and molecular aspects. (1997) (18)
- Pulmonary atresia or persistent truncus arteriosus: is it important to make the distinction and how do we do it? (2008) (17)
- Endogenous tyrosine hydroxylase activity in the developing chick heart: a possible source of extraneuronal catecholamines. (1985) (17)
- Effects of prenatal capsaicin treatment on fetal spontaneous activity, opiate receptor binding, and acid phosphatase in the spinal cord (1982) (17)
- Histamine-Induced Relaxation of Rat Aorta (1984) (16)
- Images in cardiovascular medicine. Approaching cardiac development in three dimensions by magnetic resonance microscopy. (2003) (16)
- Development of ANS Innervation to the Avian Heart (1986) (15)
- Calcium Dependent CAMTA1 in Adult Stem Cell Commitment to a Myocardial Lineage (2012) (15)
- Nodose placode provides ectomesenchyme to the developing chick heart in the absence of cardiac neural crest (1988) (15)
- Pathogenesis of persistent truncus arteriosus induced by nimustine hydrochloride in chick embryos. (1989) (14)
- Changes in [3H]naloxone binding in spinal cord of rats treated prenatally with morphine (1983) (14)
- Differential expression of a proteasomal subunit during chick development. (1997) (14)
- Morphine in Fetuses after Maternal Injection: Increasing Concentration with Advancing Gestational Age (1979) (13)
- Neural Crest Ablation Versus Sham Surgical Effects in a Chick Embryo Model of Defective Cardiovascular Development (1993) (12)
- Calcium signaling regulates ventricular hypertrophy during development independent of contraction or blood flow. (2015) (12)
- Images in cardiovascular medicine. Time-lapse study with high speed video camera in the early embryonic chick heart to visualize a time window of normal and abnormal heart development. (2002) (12)
- Cardiovascular Development: Neural Crest and New Perspectives (1995) (12)
- Drug modification of catecholamine synthesis and uptake in early chick embryos (1978) (11)
- Cardiac development and perinatal care of infants with neural crest-associated conotruncal defects. (1996) (11)
- Muscarinic acetylcholine receptors in chick heart: Influence of heat and N-ethylmaleimide on receptor conformations and interactions with guanine nucleotide-dependent regulatory proteins (1985) (11)
- Recovery of spinal cord volume in postnatal rats following prenatal exposure to morphine. (1983) (11)
- Reduction of fetal rat spinal cord volume following maternal morphine injection (1980) (11)
- Compensatory responses and development of the nodose ganglion following ablation of placodal precursors in the embryonic chick (Gallus domesticus) (1995) (11)
- Developmental characteristics of the chick nodose ganglion. (1994) (10)
- Effects of chronic morphine administration on catecholamines and beta-adrenergic receptors of the superior cervical ganglion and iris of the rat. (1982) (10)
- Proteins Associated with Cardiac Neural Crest in the Pharyngeal Region of Early Chick Embryos (1993) (9)
- Cyclic AMP in normal and sympathetically aneural chick hearts during development. (1986) (9)
- A fluorescence study on the ability of the notochord to synthesize and store catecholamines in early chick embryos. (1972) (9)
- Neural crest function in thymus development. (1989) (9)
- Electrocardiographic QT Prolongation after Ablation of the Nodose Placode in the Chick Embryo: A Developmental Model of the Idiopathic Long QT Syndrome1 (1989) (9)
- Neural crest and the morphogenesis of Down syndrome with special emphasis on cardiovascular development. (1991) (9)
- Neurotrophin‐3 and TrkC are expressed in the outflow tract of the developing chicken heart (2004) (9)
- Role of extracardiac factors in heart development (1988) (9)
- Analysis of Cx43α1 Promoter Function in the Developing Zebrafish Embryo (2001) (8)
- The effects of high phenylalanine concentration on chick embryonic development (1990) (8)
- Increase in the cholinergic cardiac plexus in sympathetically aneural chick hearts (1987) (8)
- Differential expression of the L10 ribosomal protein during heart development. (1995) (8)
- Getting to the heart of cardiac morphogenesis. (2001) (7)
- Blocking hedgehog signaling after ablation of the dorsal neural tube allows regeneration of the cardiac neural crest and rescue of outflow tract septation. (2009) (7)
- An ultrastructural morphometric study of developing rat substantia gelatinosa (1981) (7)
- Double aortic arch with aortic atresia and left-sided type B interruption. (2010) (7)
- [Studies on morphogenesis and visualization of the early embryonic heart with regard to the development of conotruncal heart defects]. (2004) (6)
- Analysis of Cx43alpha1 promoter function in the developing zebrafish embryo. (2001) (6)
- Chronotropic Responses of Chick Atria to Field Stimulation After Various Neural Crest Ablations (1989) (6)
- Use of a repetitive mouse B2 element to identify transplanted mouse cells in mouse-chick chimeras. (1999) (6)
- Take heart in the age of "omics". (2004) (6)
- Appearance of acid phosphatase in neonatal rat substantia gelatinosa (2004) (5)
- Effects of morphine on superior cervical ganglion and iris of the immature rat (1983) (5)
- Approaching Cardiac Development in Three Dimensions by Magnetic Resonance Microscopy in (2003) (5)
- Mouse models of congenital heart defects: what's missing? (2010) (5)
- Corrigendum to “FGF8 signaling is chemotactic for cardiac neural crest cells” [Dev. Biol. 354 (2011) 18–30] (2012) (4)
- Int-2 Influences the Development of the Nodose Ganglion (1995) (4)
- Persistent truncus arteriosus is associated with decreased expression of HIRA by cardiac neural crest cells in chick embryos (1999) (4)
- Absence of correlation between transient cranial hemorrhages and congenital malformations following neural crest ablation in chicks. (1996) (4)
- Deficiency of the Wnt receptor Ryk causes multiple cardiac and outflow tract defects (2018) (4)
- Whither complexity in myocardial development? (2000) (3)
- Morphine blocks the increase in acid phosphatase in the substantia gelatinosa during pain (1983) (3)
- Hemodynamic changes precede development of persistent truncus arteriosus in neural crestablated chick embryos (1990) (3)
- Carbohydrate, lipid and oxidative metabolism in the sympathetically aneural chick heart. (1987) (3)
- Experimentally Induced Long QT Syndrome in the Chick Embryo a (1990) (3)
- Role of Cardiac Neural Crest in the Development of the Caudal Pharyngeal Arches, the Cardiac Outflow and Disease (2010) (2)
- Smooth muscle alpha-actin downregulation in cultured chick aortic smooth muscle and neural crest cells is associated with altered cell shape. (1996) (2)
- Neural Crest and Heart Development (2001) (2)
- A New Perspective on the Development of the Coronary Arteries in the Chick Embryo (1990) (2)
- Developmental Aspects of the Cardiovascular System: DORV and Red Herrings (1998) (2)
- The Role of the Neural Crest in the Development of the Immune System and Endocrine Organs (2018) (1)
- Arterial pole progenitors interpret opposing FGF/BMP signals to proliferate or differentiate (2010) (1)
- Interspecific chimeras. Transplantation of neural crest between mouse and chick embryos. (2000) (1)
- Morphologic and hemodynamic assessment of TUPLE 1 gene attenuated chick embryos. (1996) (1)
- Chapter 61 – Development of the Fetal Heart (2004) (1)
- Actin and myosin isoforms in aneural and malformed chick hearts. (1990) (1)
- Comprar Cardiac Development | Margaret Loewy Kirby | 9780195178197 | Oxford University Press (2007) (1)
- Transient cranial hemorrhage does not cause depressed contractility in cardiac neural crest-ablated chick embryos. (1997) (1)
- [3H] naloxone binding in the brains of young rats perinatally exposed to methadone (1984) (1)
- The diverse roles of neural crest in cardiovascular development: myocardial function, aortic arch repatterning and outflow septation (1998) (1)
- Overview of Problems and Approaches in Heart Development (1990) (1)
- Dravet syndrome (severe myoclonic epilepsy of infancy) (2009) (1)
- EUResearch Advances Series Role of Neural Crest in Congenital Heart Disease (2005) (0)
- Abstract 13935: Ca2+ Signaling is Required for Cardiomyocyte Hypertrophy During Chamber Development Independent of Contraction or Blood Flow (2013) (0)
- Seminars in Cell and Developmental Biology Model Systems for the Study of Heart Development and Disease (2006) (0)
- A unifying concept of heart tube formation for avians and mammals (2008) (0)
- 5th International Symposium on Vascular Neuroeffector Mechanisms (1984) (0)
- Why don't they beat?: Cripto, apelin/APJ, and myocardial differentiation. (2009) (0)
- The role of the neural crest in cardiac development (2018) (0)
- Plastic embedded Golgi sections for light microscopy: a quick method. (1978) (0)
- Margaret Kirby: a cardiologist against the odds. Interview by Ruth Williams. (2012) (0)
- Conotruncal Heart Defects: Altered Tissue Morphology and Hemodynamics (2017) (0)
- Embryogenesis of Transposition of the Great Arteries (2002) (0)
- DYSENTERY. (1950) (0)
- Calcineurin Inhibition During Zebrafish Heart Development Blocks Ventricular Cardiomyocyte Hypertrophy and Leads to a Spectrum of Heart Defects (2012) (0)
- A parallel analysis of proepicardial cells in transgenic mice with dominant negative inhibition of connexin43 targeted only to neural crest cells (2002) (0)
- Morphologic and hemodynamic assessment of the TUPLE1 gene-attenuated embryos. (1996) (0)
- Creativity in Nursing (And Other Professions) (1982) (0)
- Does Neural Crest Ablation Delay or Inhibit Maturation of the Conduction System of the Chick Embryonic Heart? (2004) (0)
- Three-dimensional OCT imaging of the embryonic chick heart (2003) (0)
- Cardiac arterial pole development is conserved in vertebrates (2006) (0)
- Phthisis (1889) (0)
- Functional attenuation in cardiac neural crest of HIRA or ARV results in persistent truncus arteriosis (1997) (0)
- a large in vitro gene profile data set'' data filtering to identify new angiogenesis targets from : Focus on ''In silico Separating the wheat from the chaff (2015) (0)
- Three-dimensional optical coherence tomography: Applications to chick embryo cardiac development and drosophila melanogaster circulatory function (2003) (0)
- Optical coherence tomography (OCT) - a new method to study cardiac morphology and development in chick embryos (2002) (0)
- Expression pattern of chick achaete-scute homologue (CASH) associated with mid-embryogenesis (stages 23 to 28) (1995) (0)
- Laser ablation and fate mapping. (2000) (0)
- Profiles in Cardiovascular Science (2012) (0)
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