Mike M. Mueckler
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Mike M. Muecklerbiology Degrees
Biology
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Molecular Biology
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Biochemistry
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Biology
Mike M. Mueckler's Degrees
- Bachelors Biochemistry University of California, Berkeley
- PhD Molecular Biology Stanford University
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(Suggest an Edit or Addition)Mike M. Mueckler's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Sequence and structure of a human glucose transporter. (1985) (1401)
- Facilitative glucose transporters. (1994) (1091)
- The SLC2 (GLUT) family of membrane transporters. (2013) (891)
- Glucose transporters in the 21st Century. (2010) (793)
- Elevated levels of glucose transport and transporter messenger RNA are induced by ras or src oncogenes. (1987) (787)
- A gene encoding a transmembrane protein is mutated in patients with diabetes mellitus and optic atrophy (Wolfram syndrome) (1998) (737)
- mTOR·RICTOR Is the Ser473 Kinase for Akt/Protein Kinase B in 3T3-L1 Adipocytes* (2005) (625)
- The Mechanism of Insulin Resistance Caused by HIV Protease Inhibitor Therapy* (2000) (580)
- Nomenclature of the GLUT/SLC2A family of sugar/polyol transport facilitators. (2002) (389)
- GLUT8 is a glucose transporter responsible for insulin-stimulated glucose uptake in the blastocyst. (2000) (309)
- Family of Glucose-Transporter Genes: Implications for Glucose Homeostasis and Diabetes (1990) (305)
- Hyperglycemia induces apoptosis in pre-implantation embryos through cell death effector pathways (1998) (284)
- Mechanism of enhanced insulin sensitivity in athletes. Increased blood flow, muscle glucose transport protein (GLUT-4) concentration, and glycogen synthase activity. (1993) (268)
- Evidence from transgenic mice that glucose transport is rate-limiting for glycogen deposition and glycolysis in skeletal muscle. (1993) (263)
- Indinavir inhibits the glucose transporter isoform Glut4 at physiologic concentrations (2002) (250)
- Wolframin Expression Induces Novel Ion Channel Activity in Endoplasmic Reticulum Membranes and Increases Intracellular Calcium* (2003) (201)
- Skeletal muscle glucose transport and metabolism are enhanced in transgenic mice overexpressing the Glut4 glucose transporter. (1995) (179)
- Overexpression of Glut4 protein in muscle increases basal and insulin-stimulated whole body glucose disposal in conscious mice. (1995) (173)
- Distribution of glucose transporter messenger RNA transcripts in tissues of rat and man. (1987) (168)
- Glucose transport and apoptosis (2000) (164)
- Maternal hyperglycemia alters glucose transport and utilization in mouse preimplantation embryos. (1998) (152)
- Structural analysis of the GLUT1 facilitative glucose transporter (review). (2001) (152)
- Insulin-stimulated GLUT4 Translocation Is Mediated by a Divergent Intracellular Signaling Pathway (*) (1995) (152)
- The Mammalian Glucose Transporters (1992) (146)
- Amino acid substitutions at tryptophan 388 and tryptophan 412 of the HepG2 (Glut1) glucose transporter inhibit transport activity and targeting to the plasma membrane in Xenopus oocytes. (1992) (139)
- Insulin unmasks a COOH-terminal Glut4 epitope and increases glucose transport across T-tubules in skeletal muscle (1996) (131)
- A High Fat Diet Impairs Stimulation of Glucose Transport in Muscle (1998) (128)
- The human glucose transporter can insert posttranslationally into microsomes (1986) (126)
- Differential regulation of two distinct glucose transporter species expressed in 3T3-L1 adipocytes: effect of chronic insulin and tolbutamide treatment. (1989) (124)
- Intracellular targeting of the insulin-regulatable glucose transporter (GLUT4) is isoform specific and independent of cell type (1991) (124)
- Topology of the Glut 1 glucose transporter deduced from glycosylation scanning mutagenesis. (1994) (121)
- Molecular cloning, sequence, and tissue distribution of the human ubiquitin-activating enzyme E1. (1991) (121)
- Glucose transporter levels in spontaneously obese (db/db) insulin-resistant mice. (1990) (121)
- Germline manipulation of glucose homeostasis via alteration of glucose transporter levels in skeletal muscle. (1993) (114)
- Functional expression of the human HepG2 and rat adipocyte glucose transporters in Xenopus oocytes. Comparison of kinetic parameters. (1989) (107)
- Glucose transport activity in skeletal muscles from transgenic mice overexpressing GLUT1. Increased basal transport is associated with a defective response to diverse stimuli that activate GLUT4. (1994) (107)
- How cells absorb glucose. (1992) (106)
- Enhanced O-GlcNAc protein modification is associated with insulin resistance in GLUT1-overexpressing muscles. (2002) (105)
- Indinavir induces acute and reversible peripheral insulin resistance in rats. (2002) (104)
- Insulin-sensitive targeting of the GLUT4 glucose transporter in L6 myoblasts is conferred by its COOH-terminal cytoplasmic tail (1995) (97)
- A mutation in the Glut2 glucose transporter gene of a diabetic patient abolishes transport activity. (1994) (94)
- Effects of altered glucose homeostasis on glucose transporter expression in skeletal muscle of the rat. (1990) (93)
- Glutamine 161 of Glut1 glucose transporter is critical for transport activity and exofacial ligand binding. (1994) (87)
- Sequence of the precursor to rat ornithine aminotransferase deduced from a cDNA clone. (1985) (80)
- Cloning and functional expression of a human pancreatic islet glucose-transporter cDNA. (1989) (80)
- Hyperglycemia induces apoptosis in pre-implantation embryos through cell death effector pathways (2002) (79)
- Insulin-stimulated translocation of the HepG2/erythrocyte-type glucose transporter expressed in 3T3-L1 adipocytes. (1989) (79)
- Dissociation of GLUT4 Translocation and Insulin-stimulated Glucose Transport in Transgenic Mice Overexpressing GLUT1 in Skeletal Muscle* (1998) (77)
- Glucose transporters in the 21 st Century (2010) (74)
- Differential regulation of the HepG2 and adipocyte/muscle glucose transporters in 3T3L1 adipocytes. Effect of chronic glucose deprivation. (1990) (72)
- Model of the exofacial substrate-binding site and helical folding of the human Glut1 glucose transporter based on scanning mutagenesis. (2009) (71)
- A Conserved Amino Acid Motif (R-X-G-R-R) in the Glut1 Glucose Transporter Is an Important Determinant of Membrane Topology* (1999) (71)
- Translational and pretranslational control of ornithine aminotransferase synthesis in rat liver. (1983) (68)
- Evidence for an insulin receptor substrate 1 independent insulin signaling pathway that mediates insulin-responsive glucose transporter (GLUT4) translocation. (1996) (65)
- Kinetics of 2-deoxyglucose transport in skeletal muscle: effects of insulin and contractions. (1995) (65)
- Subcellular Distribution and Differential Expression of Endogenous ADP-ribosylation Factor 6 in Mammalian Cells* (1998) (63)
- Insulin resistance in Type 2 (non-insulin-dependent) diabetic patients and their relatives is not associated with a defect in the expression of the insulin-responsive glucose transporter (GLUT-4) gene in human skeletal muscle (1992) (61)
- Regulation of lipopolysaccharide-induced increases in neutrophil glucose uptake. (2007) (60)
- Analysis of Transmembrane Segment 10 of the Glut1 Glucose Transporter by Cysteine-scanning Mutagenesis and Substituted Cysteine Accessibility* (2002) (59)
- Phosphoinositide-dependent Kinase-2 Is a Distinct Protein Kinase Enriched in a Novel Cytoskeletal Fraction Associated with Adipocyte Plasma Membranes* (2003) (58)
- Differential effects of GLUT-1 or GLUT-4 overexpression on insulin responsiveness in transgenic mice. (1994) (57)
- Domains that confer intracellular sequestration of the Glut4 glucose transporter in Xenopus oocytes. (1993) (57)
- Glucose transporter gene expression in rat brain: Pretranslational changes associated with chronic insulin-induced hypoglycemia, fasting, and diabetes (1991) (56)
- Post-translational insertion of fragment of the glucose transporter into microsomes requires phosphoanhydride bond cleavage (1986) (53)
- Insulin resistance and the disruption of Glut4 trafficking in skeletal muscle. (2001) (52)
- Adverse metabolic consequences of HIV protease inhibitor therapy: the search for a central mechanism. (2001) (52)
- Structure and function of rat liver polysome populations. I. Complexity, frequency distribution, and degree of uniqueness of free and membrane-bound polysomal polyadenylate-containing RNA populations (1981) (50)
- Expression of genes involved in placental glucose uptake and transport in the nonobese diabetic mouse pregnancy. (1994) (48)
- Transmembrane Segment 5 of the Glut1 Glucose Transporter Is an Amphipathic Helix That Forms Part of the Sugar Permeation Pathway* (1999) (44)
- Transcriptional control of ornithine aminotransferase synthesis in rat kidney by estrogen and thyroid hormone. (1984) (44)
- Amino acid sequence of S-adenosyl-L-homocysteine hydrolase from rat liver as derived from the cDNA sequence. (1987) (43)
- Transmembrane Segment 12 of the Glut1 Glucose Transporter Is an Outer Helix and Is Not Directly Involved in the Transport Mechanism* (2006) (42)
- The Glut 1 Glucose Transporter Interacts with Calnexin and Calreticulin* (1996) (41)
- Cysteine-scanning mutagenesis of transmembrane segment 11 of the GLUT1 facilitative glucose transporter. (2000) (41)
- Implications for Glucose Homeostasis and Diabetes (1990) (40)
- Cysteine-scanning Mutagenesis and Substituted Cysteine Accessibility Analysis of Transmembrane Segment 4 of the Glut1 Glucose Transporter* (2005) (40)
- Structure, function and biosynthesis of GLUT1. (1997) (39)
- Transgenic Overexpression of Hexokinase II in Skeletal Muscle Does Not Increase Glucose Disposal in Wild-type or Glut1-overexpressing Mice* (2000) (39)
- Transmembrane Segment 6 of the Glut1 Glucose Transporter Is an Outer Helix and Contains Amino Acid Side Chains Essential for Transport Activity* (2008) (38)
- Polymorphisms of HepG2/Erythrocyte Glucose-Transporter Gene: Linkage Relationships and Implications for Genetic Analysis of NIDDM (1990) (34)
- Cellular mechanism of the insulin-like effect of growth hormone in adipocytes. Rapid translocation of the HepG2-type and adipocyte/muscle glucose transporters. (1992) (33)
- GLUT-1 or GLUT-4 transgenes in obese mice improve glucose tolerance but do not prevent insulin resistance. (1999) (31)
- Discrete structural domains determine differential endoplasmic reticulum to Golgi transit times for glucose transporter isoforms. (1994) (30)
- Analysis of Transmembrane Segment 8 of the GLUT1 Glucose Transporter by Cysteine-scanning Mutagenesis and Substituted Cysteine Accessibility* (2004) (29)
- Level of skeletal muscle glucose transporter protein correlates with insulin-stimulated whole body glucose disposal in man (1991) (28)
- Identification of pp68 as the Tyrosine-phosphorylated Form of SYNCRIP/NSAP1 (2002) (28)
- Structure, function and biosynthesis of GLUTI (1997) (27)
- Defect in insulin action on expression of the muscle/adipose tissue glucose transporter gene in skeletal muscle of type 1 diabetic patients. (1992) (26)
- Regulation of ornithine aminotransferase mRNA levels in rat kidney by estrogen and thyroid hormone. (1983) (24)
- Transmembrane Segment 3 of the Glut1 Glucose Transporter Is an Outer Helix* (2004) (24)
- Homeostasis without a GLUT (1995) (24)
- Relative Proximity and Orientation of Helices 4 and 8 of the GLUT1 Glucose Transporter* (2004) (23)
- The molecular biology of glucose transport: relevance to insulin resistance and non-insulin-dependent diabetes mellitus. (1993) (23)
- Functional consequences of proline mutations in the putative transmembrane segments 6 and 10 of the glucose transporter GLUT1. (1995) (22)
- In vitro synthesis and processing of a precursor to ornithine aminotransferase. (1982) (22)
- Identification of Amino Acid Residues within the C Terminus of the Glut4 Glucose Transporter That Are Essential for Insulin-stimulated Redistribution to the Plasma Membrane* (2008) (22)
- Purification and characterization of mammalian glucose transporters expressed in Pichia pastoris. (2010) (21)
- Mapping Novel Pancreatic Islet Genes to Human Chromosomes (1997) (20)
- Investigating the cellular targets of HIV protease inhibitors: implications for metabolic disorders and improvements in drug therapy. (2002) (19)
- Different mammalian facilitative glucose transporters expressed in Xenopus oocytes. (1990) (18)
- Differential expression of rat pancreatic islet Beta-cell glucose transporter (GLUT 2), proinsulin and islet amyloid polypeptide genes after prolonged fasting, insulin-induced hypoglycaemia and dexamethasone treatment (1992) (18)
- Reconstitution of Phosphoinositide 3-Kinase-dependent Insulin Signaling in a Cell-free System* (2003) (18)
- Rat serine dehydratase gene codes for two species of mRNA of which only one is translated into serine dehydratase. (1990) (18)
- A Novel 68-kDa Adipocyte Protein Phosphorylated on Tyrosine in Response to Insulin and Osmotic Shock* (2000) (17)
- Transgenic mice overexpressing GLUT-1 protein in muscle exhibit increased muscle glycogenesis after exercise. (2000) (17)
- Ligand-independent GLUT4 translocation induced by guanosine 5'-O-(3-thiotriphosphate) involves tyrosine phosphorylation. (1998) (16)
- Glucose Transport and Glucose Homeostasis: New Insights From Transgenic Mice (1995) (15)
- Glucokinase, glucose sensing, and diabetes. (1993) (14)
- Structure and function of rat liver polysome populations. II. Characterization of polyadenylate-containing mRNA associated with subpopulations of membrane-bound particles (1982) (12)
- Title : The SLC 2 ( GLUT ) family of membrane transporters (10)
- Levels of ornithine aminotransferase messenger RNA under conditions of cyclic AMP induction in cultured hepatocytes. (1985) (10)
- Molecular biology of receptors and transporters : receptors (1992) (9)
- Single Point Mutations Result in the Miss-Sorting of Glut4 to a Novel Membrane Compartment Associated with Stress Granule Proteins (2013) (8)
- Ligand-Induced Movements of Inner Transmembrane Helices of Glut1 Revealed by Chemical Cross-Linking of Di-Cysteine Mutants (2012) (7)
- Cloning of DNA complementary to ornithine aminotransferase mRNA. (1982) (7)
- GTP analogs suppress uptake but not transport of d‐glucose analogs in Glut1 glucose transporter‐expressing Xenopus oocytes (1993) (7)
- The molecular biology of mammalian glucose transporters. (1992) (5)
- Chapter 5 Subcellular Targeting and Regulation of Glucose Transporters (1994) (5)
- Molecular biology of receptors and transporters : pumps, transporters, and channels (1993) (4)
- Molecular biology of receptors and transporters : bacterial and glucose transporters (1992) (3)
- Molecular cloning of a mouse extracellular signal regulated kinase (erk-1). (1993) (2)
- Molecular cloning, sequence, and tissue distribution of the human (2016) (1)
- Facilitative Glucose Transporters: Regulation and Possible Role in NIDDM (1991) (1)
- Molecular cloning, sequence, and tissue distribution of the human ubiquitin-activating enzyme E1. (1991) (1)
- Maternal hyperglycemia alters glucose transport and utilization in mouse preimplantation embryos. (1998) (1)
- TRANSGENIC OVEREXPRESSION OF GLUCOSE TRANSPORTERS PREVENTS DIET-INDUCED INSULIN RESISTANCE AND GLUCOSE INTOLERANCE IN MICE. • 540 (1996) (0)
- DIABETES AND THE RISK OF MISCARRIAGE (1999) (0)
- sugar/polyol transport facilitators Nomenclature of the GLUT/SLC2A family of (2011) (0)
- Introduction: Insulin-sensitive glucose transport (1996) (0)
- Erratum: Molecular cloning, sequence, and tissue distribution of the human ubiquitin-activating enzyme E1 (Proc. Natl. Acad. Sci. USA (January 1991) 88 (258-262)) (1991) (0)
- O-20: Disruption of the interaction between the insulin receptor and IRS-1 does not impair insulin stimulated GLUT4 translocation (2009) (0)
- Structure and Function of the Glucose Transporter (2020) (0)
- Molecular cloning, sequence, and tissue distribution of the human ubiquitin-activating enzyme El (protein degradation) (2018) (0)
- 第34回日本糖尿病学会年次学術集会 The Glucose Transporters of Insulin Sensitive Tissues (1991) (0)
- GLUT-1 or GLUT-4 transgenes in obese mice improve glucose tolerance but do not prevent insulin resistance. (1999) (0)
- Reconstitution of PI 3-kinase-dependent Insulin Signaling in a Cell-free System (2003) (0)
- Reply to “Diabetes and the risk of miscarriage” (1999) (0)
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