María Belén Orlowski

María Belén Orlowski's AcademicInfluence.com Rankings

Biology

#8582

World Rank

#11682

Historical Rank

Molecular Biology

#1099

World Rank

#1124

Historical Rank

Biochemistry

#1248

World Rank

#1367

Historical Rank

biology Degrees

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Biology

María Belén Orlowski's Degrees

Bachelors Biochemistry University of Buenos Aires
Masters Biochemistry University of Buenos Aires

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María Belén Orlowski's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

The γ-Glutamyl Cycle: A Possible Transport System for Amino Acids (1970) (437)
The multicatalytic proteinase complex, a major extralysosomal proteolytic system. (1990) (415)
ISOLATION OF GAMMA-GLUTAMYL TRANSPEPTIDASE FROM HOG KIDNEY. (1965) (400)
γ-Glutamyl-p-nitroanilide: A new convenient substrate for determination and study of l- and d-γ-glutamyltranspeptidase activities (1963) (359)
Evidence for the presence of five distinct proteolytic components in the pituitary multicatalytic proteinase complex. Properties of two components cleaving bonds on the carboxyl side of branched chain and small neutral amino acids. (1993) (334)
Catalytic activities of the 20 S proteasome, a multicatalytic proteinase complex. (2000) (311)
Evidence that Pituitary Cation‐Sensitive Neutral Endopeptidase Is a Multicatalytic Protease Complex (1983) (307)
CD4 Glycoprotein Degradation Induced by Human Immunodeficiency Virus Type 1 Vpu Protein Requires the Function of Proteasomes and the Ubiquitin-Conjugating Pathway (1998) (284)
A soluble metalloendopeptidase from rat brain (1983) (233)
Inhibition of the chymotrypsin-like activity of the pituitary multicatalytic proteinase complex. (1992) (210)
Ubiquitin-independent proteolytic functions of the proteasome. (2003) (207)
Targeted inhibition of the immunoproteasome is a potent strategy against models of multiple myeloma that overcomes resistance to conventional drugs and nonspecific proteasome inhibitors. (2009) (201)
Histochemical Demonstration of Gamma-Glutamyl Transpeptidase (1961) (198)
Membrane-bound kidney neutral metalloendopeptidase: interaction with synthetic substrates, natural peptides, and inhibitors. (1983) (156)
Purification and specificity of a membrane-bound metalloendopeptidase from bovine pituitaries. (1981) (144)
Membrane bound pituitary metalloendopeptidase: apparent identity to enkephalinase. (1981) (144)
Bovine Spleen Multicatalytic Proteinase Complex (Proteasome) (1997) (144)
Soluble metalloendopeptidase from rat brain: action on enkephalin-containing peptides and other bioactive peptides. (1985) (142)
-Glutamyl cyclotransferase. Distribution, isozymic forms, and specificity. (1973) (134)
HISTOCHEMICAL AND BIOCHEMICAL INVESTIGATIONS OF GAMMA-GLUTAMYL TRANSPEPTIDASE IN THE TISSUES OF MAN AND LABORATORY RODENTS. (1964) (127)
The generation of MHC class I-associated peptides is only partially inhibited by proteasome inhibitors: involvement of nonproteasomal cytosolic proteases in antigen processing? (1997) (126)
Pituitary multicatalytic proteinase complex. Specificity of components and aspects of proteolytic activity. (1989) (123)
Glutathione metabolism and some possible functions of glutathione in the nervous system. (1976) (122)
Studies on gamma-glutamyl transpeptidase activity and its histochemical localization in the central nervous system of man and different animal species. (1966) (119)
Synaptosomal Membrane‐Bound Form of Endopeptidase‐24.15 Generates Leu‐Enkephalin from Dynorphin 1‐8, α‐ and β‐Neoendorphin, and Met‐Enkephalin from Met‐Enkephalin‐Arg6‐Gly7‐Leu (1987) (119)
Molecular cloning and primary structure of rat testes metalloendopeptidase EC 3.4.24.15. (1990) (116)
Serum γ-Glutamyl Transpeptidase Activity in Liver Disease (1961) (115)
A multicatalytic protease complex from pituitary that forms enkephalin and enkephalin containing peptides. (1981) (111)
Partial reactions catalyzed by -glutamylcysteine synthetase and evidence for an activated glutamate intermediate. (1971) (110)
gamma-Glutamyl dopa: a kidney-specific dopamine precursor. (1978) (107)
Endopeptidase 24.15 from rat testes. Isolation of the enzyme and its specificity toward synthetic and natural peptides, including enkephalin-containing peptides. (1989) (106)
Inhibition of the proteolytic activity of the multicatalytic proteinase complex (proteasome) by substrate-related peptidyl aldehydes. (1994) (104)
Substrate-related potent inhibitors of brain metalloendopeptidase. (1988) (102)
Two Novel Routes of Transporter Associated with Antigen Processing (TAP)-independent Major Histocompatibility Complex Class I Antigen Processing (1997) (101)
The gamma-glutamyl cycle: a possible transport system for amino acids. (1970) (99)
Inhibition of γ-Glutamylcysteine Synthetase by l-Methionine-S-sulfoximine (1973) (97)
Isolation and properties of gamma-L-glutamylcyclotransferase from human brain. (1969) (96)
A soluble metalloendopeptidase from rat brain. Purification of the enzyme and determination of specificity with synthetic and natural peptides. (1983) (86)
Isolation of highly purified gamma-glutamylcysteine synthetase from rat kidney. (1971) (82)
Determination of γ-glutamyl transpeptidase activity in human serum and urine (1962) (81)
Active site directed N-carboxymethyl peptide inhibitors of a soluble metalloendopeptidase from rat brain. (1984) (74)
Colorimetric determination of gamma-glutamyl transpeptidase activity in human serum and tissues with synthetic substrates. (1961) (73)
Dissociation of proteasomal degradation of biosynthesized viral proteins from generation of MHC class I-associated antigenic peptides. (1998) (72)
Subcellular Distribution of Prolyl Endopeptidase and Cation‐Sensitive Neutral Endopeptidase in Rabbit Brain (1982) (66)
Inhibition of endopeptidase 24.15 slows the in vivo degradation of luteinizing hormone-releasing hormone. (1989) (61)
GAMMA-GLUTAMYL-P-NITROANILIDE: A NEW CONVENIENT SUBSTRATE FOR DETERMINATION AND STUDY OF L- AND D-GAMMA-GLUTAMYLTRANSPEPTIDASE ACTIVITIES. (1963) (60)
The use of α-(N-γ-dl-glutamyl)-aminonitriles for the colorimetric determination of a specific peptidase in blood serum (1960) (58)
Immunocytochemical localization of endopeptidase 24.15 in rat brain (1992) (57)
Substrate and inhibitor studies of thermolysin-like neutral metalloendopeptidase from kidney membrane fractions. Comparison with bacterial thermolysin. (1986) (57)
THE ROLE OF GAMMA-GLUTAMYL TRANSPEPTIDASE IN THE INTERNAL DISEASES CLINIC. (1963) (51)
Evidence that the nature of amino acid residues in the P3 position directs substrates to distinct catalytic sites of the pituitary multicatalytic proteinase complex (proteasome). (1994) (47)
Regulation of the peptidylglutamyl-peptide hydrolyzing activity of the pituitary multicatalytic proteinase complex. (1991) (44)
Metabolism of gamma-glutamyl amino acids and peptides in mouse liver and kidney in vivo. (1976) (44)
Proteolytic enzymes in bronchopulmonary lavage fluids: cathepsin B-like activity and prolyl endopeptidase. (1981) (44)
A 3,4-dichloroisocoumarin-resistant component of the multicatalytic proteinase complex. (1992) (42)
Heterogeneity of serum γ-glutamyl transpeptidase in hepatobiliary diseases (1967) (38)
γ‐Glutamyl Transpeptidase of Sheep‐Kidney Cortex (1976) (38)
The occurrence of free L‐pyrrolidone carboxylic acid in body fluids and tissues (1973) (37)
N-acyl-gamma-glutamyl derivatives of sulfamethoxazole as models of kidney-selective prodrugs. (1980) (37)
Intermediates of the γ-Glutamyl Cycle in Mouse Tissues (1975) (37)
Reactions of [14C]-3,4-dichloroisocoumarin with subunits of pituitary and spleen multicatalytic proteinase complexes (proteasomes). (1997) (36)
Differences in Catalytic Activities and Subunit Pattern of Multicatalytic Proteinase Complexes (Proteasomes) Isolated from Bovine Pituitary, Lung, and Liver (1995) (34)
Identification and partial purification of a cation-sensitive neutral endopeptidase from bovine pituitaries. (1979) (34)
Components of the bovine pituitary multicatalytic proteinase complex (proteasome) cleaving bonds after hydrophobic residues. (1999) (32)
Synthesis of ophthalmic acid in liver and kidney in vivo. (1978) (31)
Degradation of luteinizing hormone—Releasing hormone (LHRH) by brain prolyl endopeptidase with release of des-glycinamide LHRH and glycinamide (1979) (30)
Isolation from bovine brain of a fraction containing capillaries and a fraction containing membrane fragments of the choroid plexus. (1976) (29)
Activation of γ‐glutamyl transpeptidase by monovalent cations (1973) (29)
Increased cathepsin B-like activity in alveolar macrophages and bronchoalveolar lavage fluid from smokers. (1986) (28)
Kinetic studies of sheep kidney gamma-glutamyl transpeptidase. (1976) (28)
Inhibition of endopeptidase 24.15 greatly increases the release of luteinizing hormone and follicle stimulating hormone in response to luteinizing hormone/releasing hormone. (1990) (27)
6 Enzymology of Pyrrolidone Carboxylic Acid (1971) (26)
Use of site-directed mutagenesis to identify valine-573 in the S'1 binding site of rat neutral endopeptidase 24.11 (enkephalinase). (1990) (26)
Heat shock protein-90 and the catalytic activities of the 20 S proteasome (multicatalytic proteinase complex). (2001) (26)
Synaptosomal membrane-bound form of endopeptidase-24.15 generates Leu-enkephalin from dynorphin1-8, alpha- and beta-neoendorphin, and Met-enkephalin from Met-enkephalin-Arg6-Gly7-Leu8. (1987) (25)
Identification of a thermolysin-like metalloendopeptidase in serum: activity in normal subjects and in patients with sarcoidosis. (1984) (25)
Cathepsin B and prolyl endopeptidase activity in rat peritoneal and alveolar macrophages. Stimulation of peritoneal macrophages by saline lavage. (1983) (25)
Multicatalytic proteinase complex or multicatalytic proteinase: a high-Mr endopeptidase (1988) (24)
Immunohistochemical localization of endopeptidase 24.15 in rat trachea, lung tissue, and alveolar macrophages. (1990) (24)
Evidence that enzymatic conversion of N-[1(R,S)-carboxy-3-phenylpropyl]-Ala-Ala-Phe-p-aminobenzoate, a specific inhibitor of endopeptidase 24.15, to N-[1 (R,S)-carboxy-3-phenylpropyl]-Ala-Ala is necessary for inhibition of angiotensin converting enzyme (1993) (23)
Degradation of bradykinin by isolated neutral endopeptidases of brain and pituitary. (1979) (21)
Inhibitors of an enkephalin degrading membrane-bound metalloendopeptidase: analgesic properties and effects on striatal enkephalin levels. (1984) (20)
Determination of pyrrolidone carboxylate and γ-glutamyl amino acids by gas chromatography (1975) (20)
Antinociceptive properties of inhibitors of endopeptidase 24.15. (1991) (19)
Selective activation of the 20 S proteasome (multicatalytic proteinase complex) by histone h3. (2001) (19)
Inhibition of gamma-glutamylcysteine synthetase by L-methionine-S-sulfoximine. (1973) (17)
[126] γ-Glutamyl transpeptidase (hog kidney)☆ (1970) (17)
Generation of methionine and leucine-enkephalin from precursor molecules by cation-sensitive neutral endopeptidase of bovine pituitary. (1980) (17)
Possible role of glutathione in transport processes. (1976) (17)
A Note on the occurrence of γ-glutamyl transpeptidase in human serum (1961) (15)
Peptide-degrading enzymatic activities in GH3 cells and rat anterior pituitary homogenates. (1984) (14)
Increases in opioid-mediated swim antinociception following endopeptidase 24.15 inhibition (1991) (14)
High cathepsin B activity in alveolar macrophages occurs with elastase-induced emphysema but not with bleomycin-induced pulmonary fibrosis in hamsters. (1988) (14)
Proteolytic processing of farnesylated peptides: assay and partial purification from pig brain membranes of an endopeptidase which has the characteristics of E.C. 3.4.24.15. (1994) (13)
gamma-Glutamyl transpeptidase. Determination of specificity in the presence of multiple amino acid acceptors. (1978) (13)
[Activity of serum gamma-glutamylotranspeptidase as a new enzymatic test in liver diseases. Comparison with other enzymatic tests]. (1961) (12)
Central administration of the endopeptidase 24.15 inhibitor cFP-AAF-pAB suggests dynorphin as the endogenous ligand underlying behavioral effects of milk in the fetal rat (1994) (12)
Determination of specificity of endopeptidases by combined high-performance liquid chromatography and amino acid analysis. (1982) (12)
Cathepsin B and D activity in stimulated peritoneal macrophages (1985) (11)
The estimation of the yield and content of some chemical compounds in the fruits of chosen hot pepper (Capsicum annuum L.) cultivars (2004) (11)
Structural and functional studies of the metalloendopeptidase (EC 3.4.24.15) involved in degrading gonadotropin releasing hormone. (1992) (10)
A sensitive procedure for determination of cathepsin D: activity in alveolar and peritoneal macrophages (1984) (9)
The active site of endopeptidase-24.11: substrate and inhibitor studies. (1985) (9)
Pituitary endopeptidases (2004) (8)
Intracerebroventricular infusion of inhibitors of endopeptidase-24.11 ('enkephalinase') increases the spontaneous firing frequency of an identifiable set of cells in the substantia nigra. (1987) (8)
Identification of Novel Inhibitors That Specifically Target the Immunoproteasome, and Selectively Induce Apoptosis in Multiple Myeloma and Other Immunoproteasome-Expressing Model Systems. (2005) (7)
Heterogeneity of serum gamma-glutamyl transpeptidase in hepatobiliary diseases. (1967) (7)
Phosphohexose isomerase activity of cerebrospinal fluid. Activity in bacterial meningitis and other neurological diseases. (1963) (7)
Determination of gamma-glutamyl transpeptidase activity in human serum and urine. (1962) (7)
GAMMA-Glutamyl transpeptidase of sheep-kidney cortex. Isolation, catalytic properties and dissociation into two polypeptide chains. (1976) (6)
The effect on the yield of garlic [Allium sativum L.] of autumn and spring planting using different methods of seedstalk trimming (1994) (6)
Intermediates of the gamma-glutamyl cycle in mouse tissues. Influence of administration of amino acids on pyrrolidone carboxylate and gamma-glutamyl amino acids. (1975) (6)
Some Peculiar Biological and Biochemical Properties of a Mouse Hepatoma Induced by Chrysoidin. I. Biological and Biochemical Characteristics of the Hepatoma (1960) (6)
γ-glutamyl dopa and γ-glutamyl dopamine: Effect of plasma glucose levels (1979) (6)
Endopeptidase 24.15 inhibition and opioid antinociception (2005) (5)
The estimation of biological value of leafy type parsley and its suitability for freezing. (2005) (5)
HISTOCHEMICAL AND BIOCHEMICAL INVESTIGATIONS OF GAMMA-GLUTAMYL TRANSPEPTIDASE IN RENAL CANCER OF MAN. (1964) (4)
Effect of doxapram on neostigmine evoked antagonism of vecuronium neuromuscular block. (1992) (4)
Some peculiar biological and biochemical properties of a mouse hepatoma induced by chrysoidin. III. Activity of glucose-6-phosphatase. (1960) (4)
Kidney as a site of uptake and metabolism of gamma-glutamyl compounds. (1977) (4)
The use of alpha-(N-gamma-dL-glutamyl)-aminonitriles for the colorimetric determination of a specific peptidase in blood serum. (1960) (4)
Proteolytic activity in sheep lung lymph as marker of lung capillary injury. (1987) (4)
Corrections - Molecular Cloning and Primary Structure of Rat Testes Metalloendopeptidase EC3.4.24.15 (1994) (4)
Erratum: Molecular cloning and primary structure of rat testes metalloendopeptidase EC 3.4.24.15 (Biochemistry (Nov. 13, 1990) 29:45 (10323- 10329)) (1994) (4)
Inhibition of endopeptidase 24.15 greatly increases the release of luteinizing hormone/releasing hormone. (1990) (3)
Substrate specificity and inhibitors of a capillary injury-related protease from sheep lung lymph. (1989) (3)
Molecular cloning and primary structure of rat testes metalloendopeptidase EC 3.4.24.15. (1990) (3)
Use of bumble bees for pollination of cherry tomato [produced in unheated polyethylene tunnel (2003) (3)
Gamma-glutamyl transpeptidase activity in a large population of healthy people. (1969) (3)
[201a] γ-Glutamylcysteine synthetase (Rat Kidney) (1971) (3)
[122] γ-Glutamylcyclotransferase (human brain) (1970) (3)
Determination of pyrrolidone carboxylate and gamma-glutamyl amino acids by gas chromatography. (1975) (2)
A titration method for estimating cholesterol. (1955) (2)
The effect of methods accelerating fruit ripening on the yield of small-sized tomato (2005) (2)
gamma-Glutamyl DOPA and gamma-glutamyl dopamine: effect on plasma glucose levels. (1979) (2)
The Activity of Plasma, Serum, Thrombin, and Plasmin toward Synthetic Trypsin Substrates (1968) (2)
Effect of planting density on the size and quality of shallot yield (2001) (2)
Some peculiar biological and biochemical properties of a mouse hepatoma induced by chrysoidin. II. Metabolic properties of the hepatoma. (1960) (2)
Activation of gamma-glutamyl transpeptidase by monovalent cations. (1973) (1)
[Gamma-glutamyl transpeptidase]. (1967) (1)
enkephalin-containing peptides (1989) (1)
MHC Class I-Associated Antigenic Peptides Biosynthesized Viral Proteins from Generation of Dissociation of Proteasomal Degradation of (1998) (1)
γ-GLUTAMYL DOPA AND γ-GLUTAMYL DOPAMINE AS KIDNEY SPECIFIC PRO-DRUGS (1979) (1)
Isolation and properties of a capillary injury-related protease from lung lymph. (1987) (1)
A note on the occurrence of gamma-glutamyl transpeptidase in human serum. (1961) (1)
[Biochemical bases of the early diagnosis of atherosclerosis. II. Behavior of various coagulation factors & serum proteins in artherosclerosis]. (1958) (1)
[Correlations of changes of blood lipids & various coagulation factors in the course of atherosclerosis in man]. (1958) (1)
[Correlation of changes in lipids & various blood coagulation factors in arteriosclerosis]. (1959) (1)
Lung lymph capillary injury-related protease. (1989) (1)
Results of arthroscopic meniscal repair (2017) (0)
Neural endopeptidase 24.15 and mammalian zn metalloenzymes: Models with bacterial enzymes, structural and evolutionary considerations (1993) (0)
[Phosphohexoisomerases in cerebrospinal fluid]. (1958) (0)
drugs and non-specific proteasome inhibitors models of multiple myeloma that overcomes resistance to conventional Targeted inhibition of the immunoproteasome is a potent strategy against (2008) (0)
Color count: Fruit and vegetable waste by color categories and other properties (2014) (0)
[Blood lipoprotein lipase activity in arteriosclerosis]. (1959) (0)
[Effect of dust on the state of health of workers of the Combinat Mining--Energetic Turów]. (1967) (0)
Effect of cultivation methods on the yield and quality of early potatoes. (2000) (0)
[Serum cholinesterase activity in cases of circulatory insufficiency]. (1958) (0)
[Effect of infection on the course of erythroleukemia]. (1968) (0)
Enhanced presentation by MHC class I of an influenza nucleoprotein epitope in the presence of proteasome inhibitors (1997) (0)
Influence of water magnetization on growth, yield and mineral composition of hothouse-grown cucumber and tomato (2005) (0)
[Comparative study on the activity of certain enzymes in pathological fluids and blood]. (1961) (0)
[Biochemical principles of early diagnosis of arteriosclerosis. I. behavior of blood lipids in arteriosclerosis]. (1958) (0)
[Significance of serum cholinesterase activity in some internal diseases]. (1958) (0)
Effect of some agrotechnical measures on the crop productivity of marjoram (1998) (0)
[Gamma-glutamyl-transpeptidase activity in a large population of healthy people]. (1969) (0)
Evaluation of the fruit biological value of small fruity tomato cherry type grown in unheated high plastic tunnel (2001) (0)
Multiple forms of human serum gamma-flutamyl transpeptidase. (1967) (0)
[Late enzymatic test in myocardial infarction]. (1968) (0)
Influence of the size of harvested fruits on the productivity of zucchini grown from seed sown directly in the field. (2000) (0)
Gamma glutamyl trans peptidase hog kidney (1971) (0)
Prevalence of cam-type deformities of the hip in asymptomatic adults (2014) (0)
[Serum aldolase activity in chronic heart failure]. (1958) (0)
β Synthesis and NLRP3-Mediated IL-1 β IL-1 - Multiple Cathepsins Promote Pro (2015) (0)
The late enzymatic test of myocardial infarction. (1969) (0)
Determination of aminopeptidase A activity in the serum. (1968) (0)
Analgesic Properties and Effects on Striatal Enkephalin Levels of Inhibitors of Membrane‐Bound Metalloendopeptidase (1984) (0)
The effect of methods of seedling planting and protecting plants against forst on the seed yield of kohlrabi (1998) (0)
Influence on planting density and the length of harvested shoots on the yield of New Zealand spinach. (2000) (0)
Effect of plant training on the yield of field tomato (2001) (0)
Effect of truss cutting on the yielding, quality and storage characteristics to tomato fruit cv. Camelia. (2000) (0)
[GAMMA-GLUTAMYL TRANSPEPTIDASE ACTIVITY OF THE BLOOD SERUM IN PANCREATIC DISEASES]. (1964) (0)
[Method of determination of lipoprotein lipase activity in the blood; preliminary report]. (1958) (0)
[A micromethod for the determination of lipoprotein lipase activity in the blood]. (1960) (0)
A simple method for preparation of crystalline barium glucose 6-phosphate. (1959) (0)
The effect of the size of planted clusters of bulbils on the quantity and quality of yield of biennial top onion (2002) (0)
[Behavior of the post-heparin lipolytic activity curve of the blood]. (1960) (0)
[Phosphohexoseisomerase activity in cerebrospinal fluid]. (1959) (0)

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