Matthew Frosch
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Matthew Frosch's Degrees
- Masters Artificial Intelligence Stanford University
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(Suggest an Edit or Addition)Matthew Frosch's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Neuropathological alterations in Alzheimer disease. (2011) (2397)
- National Institute on Aging–Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease (2012) (2093)
- National Institute on Aging–Alzheimer’s Association guidelines for the neuropathologic assessment of Alzheimer’s disease: a practical approach (2011) (1839)
- Common variants in MS4A4/MS4A6E, CD2uAP, CD33, and EPHA1 are associated with late-onset Alzheimer’s disease (2011) (1656)
- Correlation of Alzheimer Disease Neuropathologic Changes With Cognitive Status: A Review of the Literature (2012) (1494)
- Insulin-degrading enzyme regulates the levels of insulin, amyloid β-protein, and the β-amyloid precursor protein intracellular domain in vivo (2003) (1226)
- Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing (2019) (1073)
- Ubiquitination of a New Form of α-Synuclein by Parkin from Human Brain: Implications for Parkinson's Disease (2001) (1064)
- An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma (2019) (1007)
- A computational atlas of the hippocampal formation using ex vivo, ultra-high resolution MRI: Application to adaptive segmentation of in vivo MRI (2015) (783)
- Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma (2016) (731)
- Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo. (2003) (719)
- Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease (2017) (693)
- Enhanced Proteolysis of β-Amyloid in APP Transgenic Mice Prevents Plaque Formation, Secondary Pathology, and Premature Death (2003) (679)
- Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS (2010) (666)
- Characterization of amyloid deposition in the APPswe/PS1dE9 mouse model of Alzheimer disease (2006) (644)
- Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq (2017) (612)
- Validating novel tau positron emission tomography tracer [F‐18]‐AV‐1451 (T807) on postmortem brain tissue (2015) (553)
- The Formation of Highly Soluble Oligomers of α-Synuclein Is Regulated by Fatty Acids and Enhanced in Parkinson's Disease (2003) (544)
- Amyloid-related imaging abnormalities in amyloid-modifying therapeutic trials: Recommendations from the Alzheimer’s Association Research Roundtable Workgroup (2011) (485)
- A compendium of gene expression in normal human tissues. (2001) (480)
- Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions (2010) (475)
- PDGF B-chain in neurons of the central nervous system, posterior pituitary, and in a transgenic model (1991) (420)
- The synaptic accumulation of hyperphosphorylated tau oligomers in Alzheimer disease is associated with dysfunction of the ubiquitin-proteasome system. (2012) (369)
- Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq (2018) (368)
- Imaging Aβ Plaques in Living Transgenic Mice with Multiphoton Microscopy and Methoxy‐X04, a Systemically Administered Congo Red Derivative (2002) (364)
- Clinical manifestations of cerebral amyloid angiopathy–related inflammation (2004) (353)
- Molecular imaging with Pittsburgh Compound B confirmed at autopsy: a case report. (2007) (349)
- Reactive glia not only associates with plaques but also parallels tangles in Alzheimer's disease. (2011) (348)
- A lipophilic thioflavin-T derivative for positron emission tomography (PET) imaging of amyloid in brain. (2002) (330)
- Simple, Scalable Proteomic Imaging for High-Dimensional Profiling of Intact Systems (2015) (327)
- Parkin localizes to the Lewy bodies of Parkinson disease and dementia with Lewy bodies. (2002) (325)
- Presenilin-Mediated Modulation of Capacitative Calcium Entry (2000) (317)
- Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis (2012) (308)
- A vicious cycle of β amyloid–dependent neuronal hyperactivation (2019) (303)
- Genome-Wide Association Meta-analysis of Neuropathologic Features of Alzheimer's Disease and Related Dementias (2014) (295)
- The common inhalation anesthetic isoflurane induces caspase activation and increases amyloid β‐protein level in vivo (2008) (295)
- Emerging concepts in sporadic cerebral amyloid angiopathy. (2017) (284)
- Common variants at MS 4 A 4 / MS 4 A 6 E , CD 2 AP , CD 33 and EPHA 1 are associated with late-onset Alzheimer ’ s disease (2011) (274)
- Targeting miR‐155 restores abnormal microglia and attenuates disease in SOD1 mice (2015) (274)
- Apolipoprotein E4 effects in Alzheimer's disease are mediated by synaptotoxic oligomeric amyloid-β. (2012) (260)
- Microemboli may link spreading depression, migraine aura, and patent foramen ovale (2010) (257)
- Neuronal uptake and propagation of a rare phosphorylated high-molecular-weight tau derived from Alzheimer's disease brain (2015) (254)
- Course of cerebral amyloid angiopathy–related inflammation (2007) (237)
- Mice deficient in Mac-1 (CD11b/CD18) are less susceptible to cerebral ischemia/reperfusion injury. (1999) (223)
- Nicotinic antagonists enhance process outgrowth by rat retinal ganglion cells in culture. (1988) (222)
- Tau accumulation causes mitochondrial distribution deficits in neurons in a mouse model of tauopathy and in human Alzheimer's disease brain. (2011) (219)
- Apolipoprotein E, Especially Apolipoprotein E4, Increases the Oligomerization of Amyloid β Peptide (2012) (217)
- Effects of gender on nigral gene expression and parkinson disease (2007) (213)
- Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases. (2012) (208)
- Adult Medulloblastoma: Prognostic Factors and Patterns of Relapse (2000) (207)
- Nonsteroidal anti-inflammatory drugs lower Aβ42 and change presenilin 1 conformation (2004) (205)
- Presenilin 1 Facilitates the Constitutive Turnover of β-Catenin: Differential Activity of Alzheimer’s Disease–Linked PS1 Mutants in the β-Catenin–Signaling Pathway (1999) (202)
- Tau molecular diversity contributes to clinical heterogeneity in Alzheimer’s disease (2020) (200)
- Interstitial fluid drainage is impaired in ischemic stroke and Alzheimer’s disease mouse models (2013) (196)
- Glioblastoma recurrence after cediranib therapy in patients: lack of "rebound" revascularization as mode of escape. (2011) (195)
- Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological study (2019) (194)
- Simultaneous protection of tissue physicochemical properties using polyfunctional crosslinkers (2018) (193)
- Beta amyloid is focally deposited within the outer basement membrane in the amyloid angiopathy of Alzheimer's disease. An immunoelectron microscopic study. (1992) (191)
- Spatial relation between microbleeds and amyloid deposits in amyloid angiopathy (2010) (190)
- Validation of Clinicoradiological Criteria for the Diagnosis of Cerebral Amyloid Angiopathy-Related Inflammation. (2016) (183)
- Preservation of Neuronal Number Despite Age-Related Cortical Brain Atrophy in Elderly Subjects Without Alzheimer Disease (2008) (174)
- Pathological correlations of [F‐18]‐AV‐1451 imaging in non‐alzheimer tauopathies (2017) (173)
- Age-dependent cerebrovascular dysfunction in a transgenic mouse model of cerebral amyloid angiopathy. (2007) (173)
- High-resolution magnetic resonance imaging reveals nuclei of the human amygdala: manual segmentation to automatic atlas (2017) (171)
- Expression of APP pathway mRNAs and proteins in Alzheimer’s disease (2007) (170)
- Oral L-serine supplementation reduces production of neurotoxic deoxysphingolipids in mice and humans with hereditary sensory autonomic neuropathy type 1. (2011) (167)
- Microbleeds Versus Macrobleeds: Evidence for Distinct Entities (2009) (167)
- Vasomotion as a Driving Force for Paravascular Clearance in the Awake Mouse Brain (2019) (164)
- The Cerebral β‐Amyloid Angiopathies: Hereditary and Sporadic (2006) (164)
- Synaptic Tau Seeding Precedes Tau Pathology in Human Alzheimer's Disease Brain (2018) (159)
- Cerebrovascular lesions induce transient β-amyloid deposition. (2011) (158)
- Enhanced Dendritic Compartmentalization in Human Cortical Neurons (2018) (157)
- Differential relationships of reactive astrocytes and microglia to fibrillar amyloid deposits in Alzheimer disease. (2013) (156)
- Whole-slide imaging digital pathology as a platform for teleconsultation: a pilot study using paired subspecialist correlations. (2009) (155)
- Familial Alzheimer's Disease Presenilin 1 Mutations Cause Alterations in the Conformation of Presenilin and Interactions with Amyloid Precursor Protein (2005) (151)
- Enhanced Tau Aggregation in the Presence of Amyloid β. (2017) (151)
- Postmortem examination of patient H.M.’s brain based on histological sectioning and digital 3D reconstruction (2014) (148)
- Beneficial effect of human anti-amyloid-beta active immunization on neurite morphology and tau pathology. (2010) (146)
- Are cortical tubers epileptogenic? Evidence from electrocorticography (2009) (145)
- Molecular signature of late-stage human ALS revealed by expression profiling of postmortem spinal cord gray matter. (2004) (143)
- Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study. (2014) (140)
- Reversible cerebral vasoconstriction syndromes and primary angiitis of the central nervous system: clinical, imaging, and angiographic comparison (2016) (138)
- Is microglial apoptosis an early pathogenic change in cerebral X‐linked adrenoleukodystrophy? (2008) (135)
- Inhibitory CD161 receptor identified in glioma-infiltrating T cells by single-cell analysis (2021) (132)
- A phenotypic change but not proliferation underlies glial responses in Alzheimer disease. (2013) (130)
- Genomic characterization of human brain metastases identifies drivers of metastatic lung adenocarcinoma (2020) (127)
- The ACAT Inhibitor CP-113,818 Markedly Reduces Amyloid Pathology in a Mouse Model of Alzheimer's Disease (2004) (123)
- Prediction of cognition in Parkinson's disease with a clinical–genetic score: a longitudinal analysis of nine cohorts (2017) (122)
- TMEM106B is a genetic modifier of frontotemporal lobar degeneration with C9orf72 hexanucleotide repeat expansions (2014) (119)
- Aβ Amyloid Pathology Affects the Hearts of Patients With Alzheimer's Disease: Mind the Heart. (2016) (114)
- The ACAT Inhibitor CP-113,818 Markedly Reduces Amyloid Pathology in a Mouse Model of Alzheimer's Disease (2010) (114)
- Diagnostic value of lobar microbleeds in individuals without intracerebral hemorrhage (2015) (108)
- Hypomorphic Notch 3 alleles link Notch signaling to ischemic cerebral small-vessel disease (2011) (108)
- Total Magnetic Resonance Imaging Burden of Small Vessel Disease in Cerebral Amyloid Angiopathy: An Imaging-Pathologic Study of Concept Validation. (2016) (108)
- The cerebral beta-amyloid angiopathies: hereditary and sporadic. (2006) (107)
- Frequent and symmetric deposition of misfolded tau oligomers within presynaptic and postsynaptic terminals in Alzheimer’s disease (2014) (105)
- Detection of entorhinal layer II using Tesla magnetic resonance imaging (2005) (104)
- Diffusion magnetic resonance imaging detects pathologically confirmed, nonenhancing tumor progression in a patient with recurrent glioblastoma receiving bevacizumab. (2010) (100)
- SOD1 Suppression with Adeno-Associated Virus and MicroRNA in Familial ALS. (2020) (99)
- Studying synapses in human brain with array tomography and electron microscopy (2013) (99)
- Genetic and clinical features of progranulin-associated frontotemporal lobar degeneration. (2011) (97)
- Adult Onset Leukodystrophy with Neuroaxonal Spheroids: Clinical, Neuroimaging and Neuropathologic Observations (2009) (95)
- Elevated NADPH oxidase activity contributes to oxidative stress and cell death in Huntington's disease. (2013) (95)
- Human Brain-Derived Aβ Oligomers Bind to Synapses and Disrupt Synaptic Activity in a Manner That Requires APP (2017) (95)
- Examination of the clinicopathologic continuum of Alzheimer disease in the autopsy cohort of the National Alzheimer Coordinating Center. (2013) (95)
- Predicting the location of entorhinal cortex from MRI (2009) (95)
- Detection of isolated cerebrovascular β‐amyloid with pittsburgh compound B (2008) (93)
- Mutant presenilin 2 transgenic mice. A large increase in the levels of Abeta 42 is presumably associated with the low density membrane domain that contains decreased levels of glycerophospholipids and sphingomyelin. (2000) (92)
- Mild to moderate Alzheimer dementia with insufficient neuropathological changes (2014) (91)
- Autoradiography validation of novel tau PET tracer [F-18]-MK-6240 on human postmortem brain tissue (2019) (88)
- Predicting the location of human perirhinal cortex, Brodmann's area 35, from MRI (2013) (87)
- Microbleed and microinfarct detection in amyloid angiopathy: a high-resolution MRI-histopathology study. (2016) (85)
- H.M.'s contributions to neuroscience: A review and autopsy studies (2014) (84)
- MRI Markers of Small Vessel Disease in Lobar and Deep Hemispheric Intracerebral Hemorrhage (2010) (84)
- Differential effects of proteases involved in intracellular degradation of amyloid beta-protein between detergent-soluble and -insoluble pools in CHO-695 cells. (2002) (83)
- Blockface histology with optical coherence tomography: A comparison with Nissl staining (2014) (82)
- Overexpression of the Wild-Type SPT1 Subunit Lowers Desoxysphingolipid Levels and Rescues the Phenotype of HSAN1 (2009) (82)
- PrP is a central player in toxicity mediated by soluble aggregates of neurodegeneration-causing proteins (2019) (82)
- Lessons learned about [F-18]-AV-1451 off-target binding from an autopsy-confirmed Parkinson’s case (2017) (82)
- Seed‐competent high‐molecular‐weight tau species accumulates in the cerebrospinal fluid of Alzheimer's disease mouse model and human patients (2016) (81)
- Tau Antibody Targeting Pathological Species Blocks Neuronal Uptake and Interneuron Propagation of Tau in Vitro. (2017) (79)
- [F-18]-AV-1451 binding correlates with postmortem neurofibrillary tangle Braak staging (2017) (77)
- Tau reduction in the presence of amyloid-&bgr; prevents tau pathology and neuronal death in vivo (2018) (76)
- Cerebral amyloid angiopathy with and without hemorrhage (2015) (74)
- Multisite assessment of NIA-AA guidelines for the neuropathologic evaluation of Alzheimer's disease (2016) (73)
- Kinetics of Cerebral Amyloid Angiopathy Progression in a Transgenic Mouse Model of Alzheimer Disease (2006) (73)
- TAR-DNA Binding Protein 43 in Pick Disease (2008) (73)
- The Alzheimer-related gene presenilin 1 facilitates notch 1 in primary mammalian neurons. (1999) (73)
- Microinjection of synthetic amyloid beta-protein in monkey cerebral cortex fails to produce acute neurotoxicity. (1993) (72)
- Diffusible, highly bioactive oligomers represent a critical minority of soluble Aβ in Alzheimer’s disease brain (2018) (69)
- Enhancers active in dopamine neurons are a primary link between genetic variation and neuropsychiatric disease (2018) (67)
- C455R notch3 mutation in a Colombian CADASIL kindred with early onset of stroke (2002) (67)
- Different tau species lead to heterogeneous tau pathology propagation and misfolding (2018) (67)
- Coordinated Expression of Caspase 8, 3 and 7 mRNA in Temporal Cortex of Alzheimer Disease: Relationship to Formic Acid Extractable A&bgr;42 Levels (2006) (65)
- Plaque-Associated Local Toxicity Increases over the Clinical Course of Alzheimer Disease. (2016) (64)
- Distinct cytokine profiles in human brains resilient to Alzheimer's pathology (2019) (64)
- Matrix metalloproteinase inhibition reduces oxidative stress associated with cerebral amyloid angiopathy in vivo in transgenic mice (2009) (64)
- Characterization of GABA- and glycine-induced currents of solitary rodent retinal ganglion cells in culture (1988) (63)
- Synthetic amyloid β-protein fails to produce specific neurotoxicity in monkey cerebral cortex (1992) (61)
- Antibody-Mediated Clearance of Amyloid-β Peptide from Cerebral Amyloid Angiopathy Revealed by Quantitative In Vivo Imaging (2007) (61)
- Plasma A&bgr; Levels Do Not Reflect Brain A&bgr; Levels (2007) (61)
- Mutant SPTLC1 dominantly inhibits serine palmitoyltransferase activity in vivo and confers an age-dependent neuropathy. (2005) (61)
- Identification of neurotoxic cross-linked amyloid-β dimers in the Alzheimer's brain. (2019) (59)
- Synaptic phosphorylated &agr;-synuclein in dementia with Lewy bodies (2017) (59)
- Identification of neurotoxic cytokines by profiling Alzheimer’s disease tissues and neuron culture viability screening (2015) (58)
- 18F-Flortaucipir Binding in Choroid Plexus: Related to Race and Hippocampus Signal. (2018) (58)
- Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 14-2004. A 66-year-old man with progressive neurologic deficits. (2004) (57)
- Amyloid beta -peptide-binding alcohol dehydrogenase is a component of the cellular response to nutritional stress. (2000) (57)
- Progression of Cerebral Amyloid Angiopathy in Transgenic Mouse Models of Alzheimer Disease (2005) (56)
- Brain endothelial dysfunction in cerebral adrenoleukodystrophy. (2015) (56)
- MYD88 L265P mutation and CDKN2A loss are early mutational events in primary central nervous system diffuse large B-cell lymphomas. (2019) (55)
- Optical coherence tomography visualizes neurons in human entorhinal cortex (2015) (55)
- Alpha-Synuclein and Chaperones in Dementia With Lewy Bodies (2005) (55)
- The Acyl-Coenzyme A: Cholesterol Acyltransferase Inhibitor CI-1011 Reverses Diffuse Brain Amyloid Pathology in Aged Amyloid Precursor Protein Transgenic Mice (2010) (52)
- Clinical and biochemical correlates of insoluble α-synuclein in dementia with Lewy bodies (2006) (52)
- Absence of Alzheimer Disease Neuropathologic Changes in Eyes of Subjects With Alzheimer Disease (2017) (51)
- Postmortem Brain Levels of Urate and Precursors in Parkinson's Disease and Related Disorders (2013) (50)
- Blood-Brain Barrier Leakage and Microvascular Lesions in Cerebral Amyloid Angiopathy (2019) (50)
- Estimating Total Cerebral Microinfarct Burden From Diffusion-Weighted Imaging (2015) (50)
- Spinocerebellar Ataxia Type 7: Clinical Course, Phenotype–Genotype Correlations, and Neuropathology (2013) (50)
- The aqueous phase of Alzheimer's disease brain contains assemblies built from ∼4 and ∼7 kDa Aβ species (2015) (49)
- Thal Amyloid Stages Do Not Significantly Impact the Correlation Between Neuropathological Change and Cognition in the Alzheimer Disease Continuum (2016) (48)
- Detection of entorhinal layer II using 7Tesla [corrected] magnetic resonance imaging. (2005) (48)
- Association Between Immunosuppressive Treatment and Outcomes of Cerebral Amyloid Angiopathy-Related Inflammation. (2020) (48)
- Amyloid structure exhibits polymorphism on multiple length scales in human brain tissue (2016) (48)
- PARK10 is a major locus for sporadic neuropathologically confirmed Parkinson disease (2015) (48)
- Stable Size Distribution of Amyloid Plaques Over the Course of Alzheimer Disease (2012) (47)
- Synaptic Plasticity Defect Following Visual Deprivation in Alzheimer's Disease Model Transgenic Mice (2012) (47)
- Cost-effectiveness of IDH testing in diffuse gliomas according to the 2016 WHO classification of tumors of the central nervous system recommendations (2017) (45)
- No alteration in tau exon 10 alternative splicing in tangle-bearing neurons of the Alzheimer’s disease brain (2006) (45)
- An in vitro paradigm to assess potential anti-Aβ antibodies for Alzheimer’s disease (2018) (45)
- Meningioangiomatosis Is Associated with Neurofibromatosis 2 but not with Somatic Alterations of the NF2 Gene (1997) (43)
- Selective cell loss in Edinger-Westphal in asymptomatic elders and Alzheimer’s patients (2001) (42)
- Thinking Outside the Box: Alzheimer-Type Neuropathology That Does Not Map Directly Onto Current Consensus Recommendations (2010) (42)
- Susceptibility-weighted imaging reveals cerebral microvascular injury in severe COVID-19 (2021) (42)
- Targeted sequencing of SMO and AKT1 in anterior skull base meningiomas. (2017) (42)
- as-PSOCT: Volumetric microscopic imaging of human brain architecture and connectivity (2018) (42)
- Knowledge gaps and research recommendations for essential tremor. (2016) (41)
- Differential recognition of vascular and parenchymal beta amyloid deposition (2011) (40)
- The Boston criteria version 2.0 for cerebral amyloid angiopathy: a multicentre, retrospective, MRI–neuropathology diagnostic accuracy study (2022) (40)
- Posterior circulation stroke after C1-C2 intraarticular facet steroid injection: evidence for diffuse microvascular injury. (2010) (39)
- Rarity of the Alzheimer disease-protective APP A673T variant in the United States. (2015) (39)
- Dye‐Enhanced Multimodal Confocal Imaging as a Novel Approach to Intraoperative Diagnosis of Brain Tumors (2013) (38)
- LATE to the PART-y (2019) (38)
- Rapid Detection of Powassan Virus in a Patient With Encephalitis by Metagenomic Sequencing (2017) (37)
- Temperature-jump studies of merocyanine 540 relaxation kinetics in lipid bilayer membranes. (1985) (37)
- Increase in the relative expression of tau with four microtubule binding repeat regions in frontotemporal lobar degeneration and progressive supranuclear palsy brains (2007) (36)
- Elasticizing tissues for reversible shape transformation and accelerated molecular labeling (2020) (36)
- Cerebral Microvascular Injury in Severe COVID-19 (2020) (36)
- Allometric rules for mammalian cortical layer 5 neuron biophysics (2021) (36)
- Microglial dysfunction as a key pathological change in adrenomyeloneuropathy (2017) (36)
- Different microvascular alterations underlie microbleeds and microinfarcts (2019) (36)
- FDG hypermetabolism associated with inflammatory necrotic changes following radiation of meningioma. (1997) (35)
- CalDAG-GEFI down-regulation in the striatum as a neuroprotective change in Huntington's disease. (2010) (35)
- Matrix metalloproteinase 9–mediated intracerebral hemorrhage induced by cerebral amyloid angiopathy (2015) (35)
- Case records of the Massachusetts General Hospital. Case 36-2007. A 31-year-old woman with rash, fever, and hypotension. (2007) (35)
- Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 21-2003. A 72-year-old man with repetitive strokes in the posterior circulation. (2003) (34)
- Novel Compound Heterozygous Mutations Expand the Recognized Phenotypes of FARS2-Linked Disease (2016) (34)
- Reduced vascular amyloid burden at microhemorrhage sites in cerebral amyloid angiopathy (2016) (34)
- Efficacy of surgical treatment of de novo, adult-onset, cryptogenic, refractory focal status epilepticus. (2006) (33)
- Somatic genomic changes in single Alzheimer’s disease neurons (2022) (33)
- Outcome in Patients with H1N1 Influenza and Cerebrovascular Injury Treated with Extracorporeal Membrane Oxygenation (2011) (33)
- Plasma Abeta levels do not reflect brain Abeta levels. (2007) (32)
- Synaptic phosphorylated a-synuclein in dementia with Lewy bodies (2017) (31)
- Microbleeds on MRI are associated with microinfarcts on autopsy in cerebral amyloid angiopathy (2016) (31)
- Advancing diagnostic criteria for sporadic cerebral amyloid angiopathy: Study protocol for a multicenter MRI-pathology validation of Boston criteria v2.0 (2019) (31)
- Modeling Intracerebral Hemorrhage Growth and Response to Anticoagulation (2012) (30)
- Clinical and biochemical correlates of insoluble alpha-synuclein in dementia with Lewy bodies. (2006) (30)
- Physiology and pharmacology of olfactory bulb neurons in dissociated cell culture (1984) (30)
- Cerebellar Microbleed Distribution Patterns and Cerebral Amyloid Angiopathy. (2019) (30)
- Neuropathological correlates of cortical superficial siderosis in cerebral amyloid angiopathy (2020) (28)
- Spinal cord glioblastoma: 25years of experience from a single institution (2016) (28)
- Cerebrovascular Senescence Is Associated With Tau Pathology in Alzheimer's Disease (2020) (27)
- A new Thr49Pro transthyretin gene mutation associated with leptomeningeal amyloidosis (2008) (27)
- Effects of apoE isoforms on beta-amyloid-induced matrix metalloproteinase-9 in rat astrocytes (2006) (26)
- Progressive multifocal cystlike cortical tubers in tuberous sclerosis complex: Clinical and neuropathologic findings (2009) (26)
- Endosulfine-alpha inhibits membrane-induced α-synuclein aggregation and protects against α-synuclein neurotoxicity (2017) (26)
- Author Correction: Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing (2019) (26)
- Absence of C9ORF72 expanded or intermediate repeats in autopsy‐confirmed Parkinson's disease (2014) (25)
- Histopathology of diffusion imaging abnormalities in cerebral amyloid angiopathy (2019) (25)
- APP Mutations in Cerebral Amyloid Angiopathy with or without Cortical Calcifications: Report of Three Families and a Literature Review. (2017) (24)
- Identifying brain neoplasms using dye-enhanced multimodal confocal imaging. (2012) (24)
- Poly(adenosine diphosphate ribose) polymerase inhibition modulates spinal cord dysfunction after thoracoabdominal aortic ischemia-reperfusion. (2005) (24)
- [18F]-AV-1451 binding profile in chronic traumatic encephalopathy: a postmortem case series (2019) (23)
- Financially effective test algorithm to identify an aggressive, EGFR-amplified variant of IDH-wildtype, lower-grade diffuse glioma. (2018) (23)
- Cytochrome oxidase and neurofilament reactivity in monocularly deprived human primary visual cortex. (2007) (21)
- A single cell-based atlas of human microglial states reveals associations with neurological disorders and histopathological features of the aging brain (2018) (21)
- Tracking the earliest pathologic changes in Alzheimer disease (2014) (21)
- Entorhinal verrucae geometry is coincident and correlates with Alzheimer’s lesions: a combined neuropathology and high-resolution ex vivo MRI analysis (2011) (20)
- August 2000: Two cases with necrosis and hemorrhage in the putamen and white matter. (2001) (20)
- Risk of Transmissibility From Neurodegenerative Disease-Associated Proteins: Experimental Knowns and Unknowns (2020) (20)
- Perivascular space dilation is associated with vascular amyloid-β accumulation in the overlying cortex (2021) (19)
- Case records of the Massachusetts General Hospital. Case 12-2009. A 46-year-old man with migraine, aphasia, and hemiparesis and similarly affected family members. (2009) (19)
- In vivo characterization of spontaneous microhemorrhage formation in mice with cerebral amyloid angiopathy (2020) (18)
- Enhanced Virus Detection and Metagenomic Sequencing in Patients with Meningitis and Encephalitis (2020) (18)
- The gonadotropin-releasing hormone receptor gene promoter directs pituitary-specific oncogene expression in transgenic mice. (1999) (18)
- Genomic Analysis of Posterior Fossa Meningioma Demonstrates Frequent AKT1 E17K Mutations in Foramen Magnum Meningiomas (2019) (18)
- An ultra-high speed Whole Slide Image viewing system. (2012) (17)
- Peripheral Nerve and Skeletal Muscle (2010) (17)
- Apoptosis in astrocytic neoplasms (2005) (17)
- Neuropathologic correlates of amyloid and dopamine transporter imaging in Lewy body disease (2019) (17)
- Histopathology of diffusion-weighted imaging-positive lesions in cerebral amyloid angiopathy (2020) (16)
- Case 1-2017. A 70-Year-Old Woman with Gradually Progressive Loss of Language. (2017) (16)
- Lesions without symptoms: understanding resilience to Alzheimer disease neuropathological changes (2022) (16)
- Diagnostic evaluation and monitoring of patients with posterior cortical atrophy. (2019) (16)
- Alpha-synuclein: prion or prion-like? (2019) (15)
- Life imitates art (2011) (15)
- Non-invasive laser microsurgery selectively damages populations of labeled mouse neurons: dependence on incident laser dose and absorption (1988) (15)
- Genome-encoded cytoplasmic double-stranded RNAs, found in C9ORF72 ALS-FTD brain, propagate neuronal loss (2021) (14)
- Amyloid-beta oligomerization is associated with the generation of a typical peptide fragment fingerprint (2016) (14)
- Screening for Familial APP Mutations in Sporadic Cerebral Amyloid Angiopathy (2010) (14)
- Non-uniform distribution of GABA activated chloride channels in cultured cortical neurons (1992) (13)
- Alzheimer's disease-linked presenilin mutation (PS1M146L) induces filamin expression and γ-secretase independent redistribution. (2010) (12)
- Case records of the Massachusetts General Hospital. Case 27-2005. An 80-year-old man with fatigue, unsteady gait, and confusion. (2005) (12)
- Colocalization of neurons in optical coherence microscopy and Nissl-stained histology in Brodmann’s area 32 and area 21 (2018) (12)
- Case records of the Massachusetts General Hospital. Case 38-2006. A 5-year-old boy with headache and abdominal pain. (2006) (12)
- Featured Articles National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease (2012) (11)
- Characterization of blood vessels in brain autopsies of GBM patients who received antiangiogenic treatment (2008) (11)
- Hemorrhagic primary CNS angiitis and vasoconstrictive drug exposure (2017) (11)
- Case records of the Massachusetts General Hospital. Case 22-2010. An 87-year-old woman with dementia and a seizure. (2010) (11)
- PrP-grafted antibodies bind certain amyloid β-protein aggregates, but do not prevent toxicity (2019) (10)
- Case records of the Massachusetts General Hospital. Case 18-2011. A 35-year-old HIV-positive woman with headache and altered mental status. (2011) (10)
- 18F-AV-1451 positron emission tomography in neuropathological substrates of corticobasal syndrome. (2020) (10)
- A unique familial leukodystrophy with adult onset dementia and abnormal glycolipid storage: a new lysosomal disease? (1998) (10)
- Reducing Available Soluble &bgr;-Amyloid Prevents Progression of Cerebral Amyloid Angiopathy in Transgenic Mice (2012) (10)
- Nonvasculitic, steroid‐responsive mononeuritis multiplex (1993) (10)
- Zika and histopathology in first trimester infections (2016) (10)
- Secondary Bleeding During Acute Experimental Intracerebral Hemorrhage (2019) (10)
- Genome-wide association study and functional validation implicates JADE1 in tauopathy (2021) (10)
- The Challenge of Defining Alzheimer Disease Based on Biomarkers in the Absence of Symptoms. (2019) (9)
- Does Data-Independent Acquisition Data Contain Hidden Gems? A Case Study Related to Alzheimer's Disease. (2021) (9)
- Novel Progranulin Mutation Detected in 2 Patients With FTLD (2011) (9)
- Case records of the Massachusetts General Hospital. Case 24-2007. A 20-year-old pregnant woman with altered mental status. (2007) (9)
- Spinal cord α-synuclein deposition associated with myoclonus in patients with MSA-C (2019) (9)
- No Evidence of PGRN or MAPT Gene Dosage Alterations in a Collection of Patients with Frontotemporal Lobar Degeneration (2009) (9)
- Mitochondrial Encephalopathy and Optic Neuropathy Due to m.10158 MT-ND3 Complex I Mutation Presenting in an Adult Patient: Case Report and Review of the Literature (2016) (9)
- Cerebral small vessel disease in patients with spontaneous cerebellar hemorrhage (2018) (8)
- Case records of the Massachusetts General Hospital. Case 9-2015. A 31-year-old man with personality changes and progressive neurologic decline. (2015) (8)
- Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 27-2004. A 79-year-old woman with disturbances in gait, cognition, and autonomic function. (2004) (8)
- Case records of the Massachusetts General Hospital. Case 9-2010. A 37-year-old woman with paresthesias and ataxia. (2010) (8)
- A novel GRN mutation (GRN c.708+6_+9delTGAG) in frontotemporal lobar degeneration with TDP-43-positive inclusions: clinicopathologic report of 6 cases. (2014) (8)
- Isoform-selective decrease of glycogen synthase kinase-3-beta (GSK-3β) reduces synaptic tau phosphorylation, transcellular spreading, and aggregation (2021) (8)
- A 63-Year-Old Man With Progressive Visual Symptoms (2017) (7)
- Genome-Encoded Cytoplasmic Double-Stranded RNAs, Found in C9ORF72 ALS-FTD Brain, Provoke Propagated Neuronal Death (2018) (7)
- Neurobiology of Disease Apolipoprotein E , Especially Apolipoprotein E 4 , Increases the Oligomerization of Amyloid Peptide (2017) (7)
- Isocitrate Dehydrogenase Mutations in Low-Grade Gliomas Correlate With Prolonged Overall Survival in Older Patients (2019) (7)
- Global democratic consensus on neuropathological disease criteria (2002) (7)
- Case 5 Tuberous Sclerosis Variant with Production of Rosenthal Fibers (AlphaB-Crystallin) (1993) (6)
- The INTERnational Study on Primary Angiitis of the CEntral Nervous System – A Call to the World (2014) (6)
- Abstract 36: The Boston Criteria V2.0 for Cerebral Amyloid Angiopathy: Updated Criteria and Multicenter MRI-Neuropathology Validation (2021) (6)
- Case records of the Massachusetts General Hospital. Case 10-2010. A 37-year-old woman with weakness and a mass in the brain. (2010) (6)
- Hereditary cerebral amyloid angiopathy, Piedmont-type mutation (2020) (6)
- Interpretable deep learning of myelin histopathology in age-related cognitive impairment (2022) (6)
- Impairment of visual cortical plasticity by amyloid-beta species (2021) (6)
- Continuous Monitoring of Tau-Induced Neurotoxicity in Patient-Derived iPSC-Neurons (2021) (5)
- Chapter 8 – Pathology of Degenerative Diseases of the Nervous System (2004) (5)
- Cyclic multiplex fluorescent immunohistochemistry and machine learning reveal distinct states of astrocytes and microglia in normal aging and Alzheimer’s disease (2022) (5)
- The Alzheimer Disease-Causing Presenilin-1 L435F Mutation Causes Increased Production of Soluble Aβ43 Species in Patient-Derived iPSC-Neurons, Closely Mimicking Matched Patient Brain Tissue. (2020) (5)
- Kinetics of tau aggregation reveals patient-specific tau characteristics among Alzheimer’s cases (2021) (5)
- Tuberous sclerosis variant with production of Rosenthal fibers (alpha B-crystallin). (1993) (5)
- Manifestations of Alzheimer’s disease genetic risk in the blood are evident in a multiomic analysis in healthy adults aged 18 to 90 (2022) (4)
- A multimodal imaging and analysis pipeline for creating a cellular census of the human cerebral cortex (2021) (4)
- Activity-Dependent Dysfunction in Visual and Olfactory Sensory Systems in Mouse Models of Down Syndrome (2017) (4)
- Plasma A A Levels Do Not Reflect Brain A A Levels (2007) (4)
- Targeting miR-155 restores dysfunctional microglia and ameliorates disease in the SOD1 model of ALS. (2015) (4)
- Tau aggregates: where, when, why and what consequences? (2017) (4)
- Susceptibility Etching on MRI in Patients with Microangiopathy (2017) (4)
- Ubiquitination of a Novel form of α-Synuclein by Parkin (2002) (3)
- Author Correction: Tau molecular diversity contributes to clinical heterogeneity in Alzheimer’s disease (2021) (3)
- Quantitative and histologically validated measures of the entorhinal subfields in ex vivo MRI (2022) (3)
- Wide Range of Clinical Outcomes in Patients with Gliomatosis Cerebri Growth Pattern: A Clinical, Radiographic, and Histopathologic Study. (2018) (3)
- Case 9-2010 (2010) (3)
- Entorhinal verrucae correlate with surface geometry (2012) (3)
- Case 9-2015 (2015) (3)
- A cross-disease human microglial framework identifies disease-enriched subsets and tool compounds for microglial polarization (2022) (3)
- REMOVED: Targeting miR-155 restores dysfunctional microglia and ameliorates disease in the SOD1 model of ALS (2015) (3)
- Microenvironmental landscape of human melanoma brain metastases in response to immune checkpoint inhibition. (2022) (3)
- Integrated platform for multi-scale molecular imaging and phenotyping of the human brain (2023) (3)
- In This Issue (2017) (3)
- Common Variants Near ZIC1 and ZIC4 in Autopsy‐Confirmed Multiple System Atrophy (2022) (3)
- “When sex influences the brain: implications for Alzheimer disease” (2018) (3)
- CASE RECORDS of the MASSACHUSETTS GENERAL HOSPITAL. Case 15-2016. A 32-Year-Old Man with Olfactory Hallucinations and Paresthesias. (2016) (3)
- Cytoplasmic Mislocalization of RNA Polymerase II Subunit RPB1 in Alzheimer Disease Is Linked to Pathologic Tau (2021) (2)
- 5. Are cortical tubers epileptogenic? Evidence from electrocorticography (2008) (2)
- A 40‐year‐old woman with difficulty going down stairs in high‐heeled shoes (2015) (2)
- Absence of C 9 ORF 72 expanded or intermediate repeats in autopsy confirmed Parkinson Disease (2014) (2)
- Premature vascular disease in young adult stroke: a pathology-based case series (2019) (2)
- Refractive-index matching enhanced polarization sensitive optical coherence tomography quantification in human brain tissue (2021) (2)
- Entorhinal Subfield Vulnerability to Neurofibrillary Tangles in Aging and the Preclinical Stage of Alzheimer’s Disease (2022) (2)
- Case 24-2007 : A 20-Year-Old Pregnant Woman with Altered Mental Status (2007) (2)
- Survival in Primary Progressive Aphasia: Comparison with bvFTD and FTD-ALS (P1.217) (2015) (2)
- Molecular and clinicopathologic characteristics of gliomas with EP300::BCOR fusions (2022) (2)
- Case records of the Massachusetts General Hospital. Case 14-2014. An 11-month-old girl with developmental delay. (2014) (2)
- Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 16-2002. A 41-year-old woman with global headache and an intracranial mass. (2002) (2)
- Changes in glial cell phenotypes precede overt neurofibrillary tangle formation, correlate with markers of cortical cell damage, and predict cognitive status of individuals at Braak III-IV stages (2022) (2)
- Publisher Correction: Enhancers active in dopamine neurons are a primary link between genetic variation and neuropsychiatric disease (2018) (2)
- Pentad: A reproducible cytoarchitectonic protocol and its application to parcellation of the human hippocampus (2023) (1)
- Histopathological correlates of haemorrhagic lesions on ex vivo magnetic resonance imaging in immunized Alzheimer’s disease cases (2022) (1)
- A 20-year-old man with back pain and lower extremity weakness. (2015) (1)
- Melanocortin 1 receptor activation protects against alpha-synuclein pathologies in models of Parkinson’s disease (2021) (1)
- Altered localization of nucleoporin 98 in primary tauopathies (2022) (1)
- Spinal Cord Alpha Synuclein Deposition Associated with Spinal Myoclonus in a Patient with Multiple System Atrophy of the Cerebellar Type (MSA-C) (P4.310) (2016) (1)
- An Ultra-High Speed Whole Slide Image Viewing System (2011) (1)
- Chapter 24 – Biopsy of Nerve and Muscle (2003) (1)
- Implementation and Clinical Adoption of Precision Oncology Workflows Across a Healthcare Network (2022) (1)
- Clinically-actionable Mutations in Posterior Skull Base Meningiomas (2017) (1)
- EFFECTS OF METHANOL POISONING ON THE CENTRAL NERVOUS SYSTEM (1998) (1)
- Colocalization of Parkin with α-Synuclein in the Lewy Bodies of Parkinson Disease (2002) (1)
- Changes in glial cell phenotypes precede overt neurofibrillary tangle formation, correlate with markers of cortical cell damage, and predict cognitive status of individuals at Braak III-IV stages (2022) (1)
- MPTH-61. A NOVEL TECHNIQUE TO EXPEDITE MOLECULAR GLIOMA TESTING (2016) (1)
- Inhibition of Membrane‐Induced Alpha‐Synuclein (aSyn) Aggregation: A Strategy to Interfere with aSyn Neurotoxicity in Parkinson's Disease (PD) (2017) (1)
- Malignant Melanoma Metastatic to Oligodendroglioma: Case Report and Literature Review of Tumor-to-Tumor Metastasis to Gliomas. (2018) (1)
- Refractive-index matching enhanced polarization sensitive optical coherence tomography quantification in human brain tissue. (2021) (1)
- Identification of a novel deletion in the splice donor site of progranulin exon 6 (2009) (1)
- A peptide-centric quantitative proteomics dataset for the phenotypic assessment of Alzheimer’s disease (2023) (1)
- Rapid Neurological Recovery Following Partial Surgical Resection of Spinal Glioblastoma Multiforme in a Pediatric Patient Presenting With Complete Paraplegia (2016) (1)
- Repetitive head impacts and chronic traumatic encephalopathy are associated with TDP-43 inclusions and hippocampal sclerosis (2023) (1)
- Resource Simple , Scalable Proteomic Imaging for High-Dimensional Profiling of Intact Systems Graphical Abstract Highlights (2015) (1)
- Erratum: LATE to the PART-y (Brain (2019) 142 (e47) DOI: 10.1093/brain/awz224) (2019) (1)
- A Simplified Brain Blocking Protocol Optimized for the Diagnosis of Neurodegenerative Disease Saves Time and Money While Preserving Anatomic Relationships. (2020) (1)
- Abstract W P246: Diagnostic Value of Lobar Hemorrhages for Cerebral Amyloid Angiopathy in Hospital and Community-based Individuals: A Pathological Correlation Study (2014) (1)
- Patch2MAP combines patch-clamp electrophysiology with super-resolution structural and protein imaging in identified single neurons without genetic modification (2023) (0)
- An in vitro paradigm to assess potential anti-Aβ antibodies for Alzheimer’s disease (2018) (0)
- Chapter 6 – Human Prion Diseases (2004) (0)
- Single‐Neuron Genome Sequencing in Alzheimer’s Disease Identifies Disease‐Specific Somatic Alterations and Insights into Pathogenesis (2022) (0)
- Diagnosis and Classification of Prion Diseases (2006) (0)
- APOE4 plays a role in Abeta-mediated synapse loss in Alzheimer's disease (2011) (0)
- Clinical Trial-Ready Patient Cohorts for Multiple System Atrophy: Coupling Biospecimen and iPSC Banking to Longitudinal Deep-Phenotyping (2022) (0)
- Correction to: Clinical trial-ready patient cohorts for multiple system atrophy: coupling biospecimen and iPSC banking to longitudinal deep-phenotyping. (2022) (0)
- Abstract W MP89: Validation of Clinical-Radiological Criteria for the Diagnosis of Cerebral Amyloid Angiopathy-related Inflammation (2014) (0)
- Contents Vol. 12, 2013 (2013) (0)
- In Vivo Imaging of Alzheimer Pathology in Transgenic Mice using Multiphoton Microscopy (2004) (0)
- Presence of co‐pathology in sporadic early‐onset Alzheimer disease versus dominantly inherited Alzheimer disease (2021) (0)
- GRN-related Frontotemporal Lobar Degeneration TDP43 Type A presenting as a case of Posterior Cortical Atrophy (P5.013) (2015) (0)
- A 15 year-old girl with progressive epileptic encephalopathy, myoclonus, and compound heterozygous FARS2 mutations (P5.145) (2016) (0)
- Reply to J. Rieger et al (2010) (0)
- BLOOD-BRAIN BARRIER LEAKAGE AND MICROVASCULAR LESIONS IN CEREBRAL AMYLOID ANGIOPATHY: A POSTMORTEM MRI AND HISTOPATHOLOGY STUDY (2018) (0)
- Improving the Efficiency of Molecular Brain Tumor Testing (P4.247) (2016) (0)
- IDH mutations define a subset of gliomatosis cerebri patients with improved outcome (P1.160) (2017) (0)
- P2-333 High resolution structural magnetic resonance images of the entorhinal cortex predict the presence of verrucae in 3D reconstruction volumes in control brains (2006) (0)
- Publisher Correction: Enhancers active in dopamine neurons are a primary link between genetic variation and neuropsychiatric disease (2018) (0)
- A NOVEL PARADIGM FOR THE IDENTIFICATION AND TARGETING OF BIOACTIVE ABETA SPECIES FROM ALZHEIMER BRAIN (2016) (0)
- Spinocerebellar Ataxia Type 7: Clinical Course, Phenotype–Genotype Correlations, and Neuropathology (2012) (0)
- Detection of cortical changes in Alzheimer’s disease at ultra-high field MRI Chapter (2014) (0)
- An Appreciation (1973) (0)
- Transgenic mice expressing mutant and wild type human presenilin-I (PS-1) (1997) (0)
- Autoradiography validation of novel tau PET tracer [F-18]-MK-6240 on human postmortem brain tissue (2019) (0)
- P2-076 Progression of cerebrovascular β-amyloid deposition in living mice (2004) (0)
- P3-229 Analysis of gene expression in the Alzheimer's disease brain (2004) (0)
- Enhancers active in dopamine neurons are a primary link between genetic variation and neuropsychiatric disease (2018) (0)
- Colocalization of neurons in optical coherence microscopy and Nissl-stained histology in Brodmann’s area 32 and area 21 (2018) (0)
- Effect of Gelsolin on Cerebral Amyloid Angiopathy (CAA) in Transgenic Mice (2008) (0)
- Learnings about Aβ from human brain recommend the use of a live-neuron bioassay for the discovery of next generation Alzheimer’s disease immunotherapeutics (2023) (0)
- Teaching NeuroImage: Subacute Quadriparesis From Intramedullary Spinal Cord Infiltrating Glioma With TERT Promoter Mutation. (2023) (0)
- Edinburgh Research Explorer Frequent and symmetric deposition of misfolded tau oligomers within presynaptic and postsynaptic terminals in Alzheimer¿s disease (2018) (0)
- Potential New Drug Target for Alzheimer Disease Prevention and Treatment (2003) (0)
- Melanocortin 1 receptor activation protects against alpha-synuclein pathologies in models of Parkinson’s disease (2022) (0)
- Stereology neuron counts correlate with deep learning estimates in the human hippocampal subregions (2023) (0)
- Elucidation of Amyloid-Beta’s Gambit in Oligomerization: Truncated Aβ fragments of residues Aβ1-23, Aβ1-24 and Aβ1-25 rapidly seed to form SDS-stable, LMW Aβ oligomers that impair synaptic plasticity (2022) (0)
- Edinburgh Research Explorer The synaptic accumulation of hyperphosphorylated tau oligomers in Alzheimer disease is associated with dysfunction of the ubiquitin-proteasome system (2018) (0)
- Tau aggregates: Where, When, Why and What consequences? (2017) (0)
- Cognitive & Behavioral Neurology, Memory Disorders, and Frontotemporal Disorders Units/Divisions, and MA Alzheimer's Disease Research Center Attending Staff, Harvard Partners Neurology Departments Geriatric Research, Education and Clinical Center Attending Staff, New England GRECC and ENRM Veterans (2014) (0)
- Tau imaging : pathologic correlations 3 Number of words in the body of the manuscript : 3535 Number of figures : 5 Number of color figures : 4 Number of tables : 0 (2016) (0)
- Specificity of neuronal loss in the Edinger-Westphal nucleus and its clinical implications (2000) (0)
- EFFECT OF PASSIVE IMMUNOTHERAPY ON THE RATE OF PROGRESSION OF CEREBRAL AMYLOID ANGIOPATHY (CAA) IN TRANSGENIC MICE (2007) (0)
- A unique high-molecular-weight tau species is involved in propagation and accumulates in the cerebrospinal fluid of Alzheimer’s disease patients (2015) (0)
- Case records of the Massachusetts General Hospital. Case 21-2014. A 68-year-old man with a sudden onset of diplopia. (2014) (0)
- Retracted: Elevated NADPH oxidase activity contributes to oxidative stress and cell death in Huntington's disease. (2017) (0)
- Frequent and symmetric deposition of misfolded tau oligomers within presynaptic and postsynaptic terminals in Alzheimer’s disease (2014) (0)
- Endosulfine-alpha inhibits membrane-induced α-synuclein aggregation and protects against α-synuclein neurotoxicity (2017) (0)
- [18F]-AV-1451 binding profile in chronic traumatic encephalopathy: a postmortem case series (2019) (0)
- Lessons learned about [F-18]-AV-1451 off-target binding from an autopsy-confirmed Parkinson’s case (2017) (0)
- Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological study (2020) (0)
- Abstract WP426: Cerebral Amyloid Angiopathy-related Inflammation: Immunosuppressive Treatment and Outcome (2019) (0)
- Elasticizing tissues for reversible shape transformation and accelerated molecular labeling (2020) (0)
- Spontaneous Isomerization of Asp387 in Tau is Diagnostic for Alzheimer’s Disease: An Endogenous Indicator of Reduced Autophagic Flux (2021) (0)
- Association Studies of Neuropathologically-Confirmed Cases and Controls Reveals that the PARK10 Locus is a Major Contributor to Sporadic Parkinson disease. (S7.005) (2015) (0)
- Surgical management of an abscess of the insula (2022) (0)
- BLOOD-BRAIN BARRIER LEAKAGE AND MICROVASCULAR LESIONS IN CEREBRAL AMYLOID ANGIOPATHY: A POSTMORTEM MRI AND HISTOPATHOLOGY STUDY (2018) (0)
- P1-460: Matrix metalloproteinase inhibition reduces oxidative stress associated with cerebral amyloid angiopathy in vivo in transgenic mice (2008) (0)
- Microvascular Abnormalities in Adrenoleukodystrophy: Effects of ABCD1 Deficiency Upon Brain Endothelium. (S35.005) (2015) (0)
- Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing (2019) (0)
- P4-292 Effect of immunotherapy on the rate of progression of cerebral amyloid angiopathy (CAA) in transgenic mice (2006) (0)
- A 15 year-old girl with progressive epileptic encephalopathy, progressive myoclonus, and compound heterozygous FARS2 mutations (2015) (0)
- T2 Hypointense Schwannoma Masquerading As A Vascular Lesion: A Case Report (2022) (0)
- TDP-43 and tau concurrence in the entorhinal subfields in primary age-related tauopathy and preclinical Alzheimer's disease. (2023) (0)
- Neuropsychological, clinico‐pathologic, neuroimaging, and biomarker profiles of the MGH FTD Unit posterior cortical atrophy (PCA) cohort (2020) (0)
- 18F‐Flortaucipir PET imaging compared with autopsy in a clinically and pathologically heterogeneous group of patients with neurodegenerative dementias (2021) (0)
- MRI-DERIVED CORTICAL ATROPHY PATTERNS AS PROBABILISTIC PREDICTORS OF SPECIFIC NEURODEGENERATIVE PATHOLOGIES (2019) (0)
- GENE-63. GENOMIC CHARACTERIZATION OF HUMAN BRAIN METASTASES IDENTIFIES NOVEL DRIVERS OF LUNG ADENOCARCINOMA PROGRESSION (2019) (0)
- Explorer Tau accumulation causes mitochondrial distribution deficits in neurons in a mouse model of tauopathy and in human Alzheimer ' s disease brain (2017) (0)
- P2-194: Complement pathways are upregulated in angular gyrus of primary progressive aphasia cases (2008) (0)
- Plasma biomarkers for diagnosis of Alzheimer's disease and prediction of cognitive decline in individuals with mild cognitive impairment (2022) (0)
- Expression of chemokines, metalloproteinases and cyclooxygenase in human synoviocytes by different Borrelia burgdorferi isolates (2003) (0)
- Genomic characterization of human brain metastases identifies drivers of metastatic lung adenocarcinoma (2020) (0)
- Eastern Association of Electroencephalographers, 56th Annual Meeting: ‘Ski Meeting, 2002’ Québec, Canada, February 1, 2002 (2004) (0)
- MRI‐histopathology correlations of amyloid‐related imaging abnormalities (ARIA) in postmortem human brain samples (2020) (0)
- Imaging tau Pathology In Vivo in AD and FTLD Spectrum Tauopathies with [18F] AV1451 PET (P4.010) (2016) (0)
- Impact of Sterilization Methods on the Seeding Ability of Human Tau Proteopathic Seeds. (2021) (0)
- Aβ oligomerization is associated with the generation of a typical peptide fragment 1 fingerprint . 2 3 (2017) (0)
- CNS vasculitis as early manifestation of polyarteritis nodosa (2012) (0)
- ADULT-ONSET LEUKOENCEPHALOPATHY IN TWO SIBLINGS: NEUROPATHOLOGIC AND METABOLIC STUDIES (1996) (0)
- Transcriptional profiling supports the notochordal origin of chordoma and its dependence on a TGFΒ1-TBXT network. (2023) (0)
- Abstract 4729: Identifying genomic drivers of lung adenocarcinoma brain metastases (2020) (0)
- MRI-HISTOPATHOLOGY ASSOCIATIONS OF MICROBLEEDS AND MICROINFARCTS IN INTACT EX VIVO HEMISPHERES OF PATIENTS WITH CEREBRAL AMYLOID ANGIOPATHY (2017) (0)
- “INFLAMMATORY” GLIOMAS: A DIAGNOSTIC DILEMMA (1999) (0)
- Short Communication Microin jection ofSynthetic Amyloid (3-Protein in MonkeyCerebral Cortex Fails toProduce Acute Neurotoxicity (1993) (0)
- Tau molecular diversity contributes to clinical heterogeneity in Alzheimer’s disease (2020) (0)
- P4-079 Coordinated expression of APP pathway mRNA and protein in AD (2006) (0)
- Histopathology of Cerebral Microinfarcts and Microbleeds in Spontaneous Intracerebral Hemorrhage (2022) (0)
- Early detection of hereditary cerebral amyloid angiopathy with PiB (2008) (0)
- Genome-wide association study of autopsy-confirmed Multiple System Atrophy identifies common variants near ZIC1 and ZIC4 (2021) (0)
- Chapter 23 – Biopsy of the Brain (2003) (0)
- Intersubject Regularity in the Intrinsic Shape of Human V1 (2007) (0)
- Microenvironmental correlates of immune checkpoint inhibitor response in human melanoma brain metastases revealed by T cell receptor and single-cell RNA sequencing (2021) (0)
- Effect of passive immunotherapy on the rate of progression of cerebral amyloid angiopathy (caa) in transgenic mice: 126.7 (2007) (0)
- OP-JNEN200109 1141..1146 (2020) (0)
- Explorer Frequent and symmetric deposition of misfolded tau oligomers within presynaptic and postsynaptic terminals in Alzheimer ¿ s disease (2016) (0)
- Different tau species lead to heterogeneous tau pathology propagation and misfolding (2018) (0)
- AXONAL ABNORMALITIES IN THE BRAIN OF THE ABCD1 KNOCKOUT MOUSE, AN ANIMAL MODEL OF X-LINKED ADRENOLEUKODYSTROPHY (2006) (0)
- rrucaE corrE lat E with surfacE gEomE try (2012) (0)
- "Vaccines Against Meningococcus" An update of the progresses in meningitis prevention, based on the Meningococcus Scientific Exchange Meeting, Siena, Italy, 1-3 July 2008. (2009) (0)
- P2-353: Reducing the availability of soluble Aβ halts progression of cerebral amyloid angiopathy in transgenic mice (2008) (0)
- Cyclic multiplex fluorescent immunohistochemistry and machine learning reveal distinct states of astrocytes and microglia in normal aging and Alzheimer’s disease (2022) (0)
- Clinical, radiologic, and pathologic features of the globular glial tauopathy subtype of frontotemporal lobar degeneration in right temporal variant frontotemporal dementia with salient features of Geschwind syndrome (2022) (0)
- Does DIA data contain hidden gems? A case study related to Alzheimer’s disease (2022) (0)
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What Schools Are Affiliated With Matthew Frosch?
Matthew Frosch is affiliated with the following schools:
