Michael R. Hanley

Michael R. Hanley's AcademicInfluence.com Rankings

Michael R. Hanley

Medical

#3006

World Rank

#3455

Historical Rank

Pharmacology

#348

World Rank

#399

Historical Rank

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Medical

Michael R. Hanley's Degrees

PhD Pharmacology University of California, San Diego
Bachelors Pharmacy University of California, San Francisco

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Michael R. Hanley's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase. (1990) (3014)
Lithium amplifies agonist-dependent phosphatidylinositol responses in brain and salivary glands. (1982) (1983)
Thapsigargin inhibits the sarcoplasmic or endoplasmic reticulum Ca-ATPase family of calcium pumps. (1991) (1198)
Neural and developmental actions of lithium: A unifying hypothesis (1989) (999)
The mas oncogene encodes an angiotensin receptor (1988) (368)
A novel tumour promoter, thapsigargin, transiently increases cytoplasmic free Ca2+ without generation of inositol phosphates in NG115-401L neuronal cells. (1988) (302)
Thapsigargin , a tumor promoter , discharges intracellular Ca 2 + stores by specific inhibition of the endoplasmic reticulum Ca 2 +-ATPase ( hepatocyte / microsome / calcium pump ) (207)
HHV8-encoded vMIP-I Selectively Engages Chemokine Receptor CCR8 (1999) (201)
Development of macroglial cells in rat cerebellum. I. Use of antibodies to follow earlyin vivo development and migration of oligodendrocytes (1988) (184)
Purification and characterisation of a membrane-bound substance-P-degrading enzyme from human brain. (1981) (162)
Occurrence and extracellular actions of inositol pentakis- and hexakisphosphate in mammalian brain (1987) (161)
Diverse molecular provocation of programmed cell death. (1996) (148)
Thapsigargin, a novel molecular probe for studying intracellular calcium release and storage (1989) (146)
Similar effects of substance P and related peptides on salivation and on phosphatidylinositol turnover in rat salivary glands. (1980) (146)
Tissue selectivity of substance P alkyl esters: suggesting multiple receptors. (1983) (137)
Metabolism and biological activities of inositol pentakisphosphate and inositol hexakisphosphate. (1995) (134)
Specific binding of 3H-substance P to rat brain membranes (1980) (133)
A vasopressin-like peptide in the mammalian sympathetic nervous system (1984) (132)
Thapsigargin, a novel molecular probe for studying intracellular calcium release and storage (2005) (122)
Calcium influx factor is synthesized by yeast and mammalian cells depleted of organellar calcium stores. (1999) (114)
Receptor coupled events in bradykinin action: rapid production of inositol phosphates and regulation of cytosolic free Ca2+ in a neural cell line. (1987) (110)
Evidence for a kappa-opioid receptor on pituitary astrocytes: An autoradiographic study (1985) (105)
Proto-oncogenes in the nervous system (1988) (94)
Pharmacological tools for perturbing intracellular calcium storage. (1994) (89)
Muscarinic cholinergic receptors in rat corpus striatum and regulation of guanosine cyclic 3',5'-monophosphate. (1978) (86)
myo-inositol pentakisphosphates. Structure, biological occurrence and phosphorylation to myo-inositol hexakisphosphate. (1991) (86)
Regulation of c-fos and c-jun protooncogene expression by the Ca(2+)-ATPase inhibitor thapsigargin. (1991) (80)
Peptide sequencing using the combination of edman degradation, carboxypeptidase digestion and fast atom bombardment mass spectrometry. (1982) (77)
Synthesis and biological properties of enzyme-resistant analogues of substance P. (1981) (77)
Evaluation of Calcium Influx Factors from Stimulated Jurkat T-lymphocytes by Microinjection into Xenopus Oocytes(*) (1995) (76)
Autoradiographic localization of mas proto-oncogene mRNA in adult rat brain using in situ hybridization (1990) (75)
Pharmacological characterization of a receptor for calcitonin gene‐related peptide on rat, L6 myocytes (1992) (75)
Inositol trisphosphate and thapsigargin discriminate endoplasmic reticulum stores of calcium in rat brain. (1990) (74)
The possible existence of multiple receptors for substance P (1982) (70)
Thapsigargin, but not caffeine, blocks the ability of thyrotropin-releasing hormone to release Ca2+ from an intracellular store in GH4C1 pituitary cells. (1990) (67)
Substance P Receptors (1980) (60)
Sticky fingers and CAAX boxes (1988) (59)
Characterization of metal ion-induced [3H]inositol hexakisphosphate binding to rat cerebellar membranes. (1993) (56)
Return of the magnificent seven (1987) (55)
[3H]‐QUINUCLIDINYL BENZILATE BINDING TO MUSCARINIC RECEPTORS IN RAT BRAIN: COMPARISON OF RESULTS FROM INTACT BRAIN SLICES AND HOMOGENATES (1979) (54)
Functional substance P receptors on a rat pancreatic acinar cell line (1985) (52)
Functional characterization by heterologous expression of a novel cloned tachykinin peptide receptor. (1996) (51)
Neural function: metabolism and actions of inositol metabolites in mammalian brain. (1988) (49)
Enzymatic synthesis of acetylcholine by a serotonin-containing neurone from Helix (1974) (47)
Growth factors: Neuropeptides as mitogens (1985) (47)
Substance P and bombesin elevate cytosolic Ca2+ by different molecular mechanisms in a rat pancreatic acinar cell line. (1990) (46)
Transformer and transducer (1987) (45)
Thapsigargin, a new calcium‐dependent epithelial anion secretagogue (1989) (44)
Substance P receptors in the nervous system and possible receptor subtypes. (1982) (44)
Chromatographic Resolution of an Intracellular Calcium Influx Factor from Thapsigargin-activated Jurkat Cells (1995) (43)
Stepping up the pressure (1992) (40)
The lethality and spectroscopic properties of toxins from Bungarus multicinctus (Blyth) venom. (1975) (40)
Neurotoxins of Bungarus multicinctus vernom. Purification and partial characterization. (1977) (40)
Crotoxin effects on Torpedo californica cholinergic excitable vesicles and the role of its phospholipase A activity. (1978) (39)
Phosphatidic acid and lysophosphatidic acid stimulate receptor-regulated membrane currents in the Xenopus laevis oocyte. (1992) (38)
Radiolabeled alpha-bungarotoxin derivatives: kinetic interaction with nicotinic acetylcholine receptors. (1981) (37)
Identification of a novel inflammatory stimulant of chondrocytes. Early events in cell activation by bradykinin receptors on pig articular chondrocytes. (1989) (37)
Attenuation of agonist‐induced desensitization of the rat substance P receptor by progressive truncation of the C‐terminus (1994) (37)
Phosphatidylinositol metabolism in cells transformed by polyomavirus middle T antigen (1990) (37)
17β-estradiol stimulates substance P receptor gene expression (1997) (35)
Properties of radiolabeled alpha-bungarotoxin derivatives and their interaction with nicotinic acetylcholine receptors. (1978) (34)
Improved Glucose Control and Reduced Body Weight in Rodents with Dual Mechanism of Action Peptide Hybrids (2013) (33)
THE EFFECTS OF SUBSTANCE P AND RELATED PEPTIDES ON α‐AMYLASE RELEASE FROM RAT PAROTID GLAND SLICES (1981) (33)
Autoradiographic localization of peripheral benzodiazepine, dihydroalprenolol and arginine vasopressin binding sites in the pituitaries of control, stalk transected and Brattleboro rats. (1986) (32)
Substance P antagonists (1982) (31)
Tumor promoter 12‐O‐tetradecanoylphorbol 13‐acetate inhibits mas/angiotensin receptor‐stimulated inositol phosphate production and intracellular Ca2+ elevation in the 401L‐C3 neuronal cell line (1989) (30)
Attenuation of agonist-induced desensitization of the rat substance P receptor by microinjection of inositol pentakis-and hexakisphosphates in Xenopus laevis oocytes. (1994) (29)
Neuronal degeneration induced by stereotaxic injection of β-bungarotoxin into rat brain (1979) (28)
Coping with a growing family (1987) (28)
Regulation of inositol trisphosphate-induced membrane currents in Xenopus oocytes by a Jurkat cell calcium influx factor. (1996) (26)
A phosphoinositide-linked peptide response in astrocytes: Evidence for regional heterogeneity (1988) (24)
Multiple modes of protein kinase C regulation and their significance in signalling. (1988) (24)
Identification of a novel inositol phosphate recognition site: specific [3H]inositol hexakisphosphate binding to brain regions and cerebellar membranes. (1990) (24)
The immunocytochemical localisation of ‘substance-P-degrading enzyme’ within the rat spinal cord (1987) (23)
Efficient high-throughput discovery of large peptidic hormones and biomarkers. (2006) (22)
The metabolism and functions of inositol pentakisphosphate and inositol hexakisphosphate. (1989) (22)
The role of phospholipases and phospholipid-derived signals in cell activation. (1991) (22)
Stimulation of adenylate cyclase by amylin in CHO-K1 cells. (1992) (20)
Malignant transformation by G protein-coupled hormone receptors (1994) (20)
Autoradiographic evidence for β-adrenergic receptors on capsaicin-sensitive primary afferent terminals in rat spinal cord (1987) (19)
Conformation of the neurotoxin crotoxin complex and its subunits. (1979) (19)
Changes in inositol lipids and phosphates after stimulation of the MAS-transfected NG115-401L-C3 cell line by mitogenic and non-mitogenic stimuli. (1990) (18)
A monoclonal anti-idiotypic antibody to μ and δ opioid receptors (1991) (18)
PEPTIDE REGULATORY FACTORS IN THE NERVOUS SYSTEM (1989) (18)
Inducible receptors. (1997) (17)
17beta-estradiol stimulates substance P receptor gene expression. (1997) (17)
L6 skeletal muscle cells have functional V1‐vasopressin receptors coupled to stimulated inositol phospholipid metabolism (1987) (17)
Mitogenic neurotransmitters (1989) (17)
Bradykinin stimulation of inositol phosphate and calcium responses in insensitive to pertussis toxin in NG115-401L neuronal cells. (1987) (16)
Tritiated peptides. 12. Synthesis and biological activity of [4-3H-Phe8]substance P. (1982) (16)
Evidence for multiple tachykinin receptor subtypes on the rabbit iris sphincter muscle. (1988) (15)
Acetylcholine activity in an identified 5‐hydroxytryptamine containing neuron (1974) (15)
Biochemical and Pharmacological Studies of Substance P Receptors (1982) (15)
Synthesis and metabolic stability of a tritium‐labelled substance P analogue (1982) (14)
Presence and actions of vasopressin-like peptides in the rabbit anterior uvea (1989) (13)
Calcium influx factor (CIF) as a diffusible messenger for the activation of capacitative calcium entry in Xenopus oocytes. (1999) (12)
Sympathetic denervation impairs agonist-stimulated phosphatidylinositol metabolism in rat parotid glands. (1983) (12)
Capacitative calcium influx. (1998) (12)
Effect of capsaicin on the rabbit urinary bladder. What is the function of sensory nerves that contain substance P? (1990) (12)
The mas oncogene as a neural peptide receptor: expression, regulation and mechanism of action. (1990) (11)
Substance K receptor: return of the magnificent seven. (1987) (10)
A comparison of the release of substance P and some synthetic analogues from micropipettes by microiontophoresis or pressure (1983) (10)
Amyloid precursor on the Go (1993) (10)
Down‐regulation of phorbol diester binding to NG115‐401L neuronal cells is dependent on structure, concentration and time (1987) (10)
Expression of the MAS proto-oncogene in the retinal pigment epithelium of the rhesus macaque. (1994) (10)
Solubilization and characterization of substance P-binding sites from chick brain membranes. (1988) (10)
Protein modification. Sticky fingers and CAAX boxes. (1988) (9)
Molecular and Cell Biology of Angiotensin Receptors (1991) (9)
The ras gene. Transformer and transducer. (1987) (9)
Peptide receptors. Stepping up the pressure. (1992) (8)
Protein kinase Cs. Coping with a growing family. (1987) (8)
Messenger RNA localization and further characterisation of the putative tachykinin receptor NK4 (NK3B). (2001) (6)
Molecular mechanisms of phospholipid signaling pathways in mammalian nerve cells. (1988) (6)
Molecular Biology of Peptide and Glycoprotein Hormone Receptors (1992) (6)
Inositol hexakisphosphate biosynthesis in mammalian brain: identification of a novel inositol pentakisphosphate kinase. (1990) (5)
Inositol phospholipids and phosphates for investigation of intact cell phospholipase C substrates and products. (1991) (5)
Stimulation of Ca(2+)-dependent membrane currents in Xenopus oocytes by microinjection of pyrimidine nucleotide-glucose conjugates. (1996) (5)
Substance P analog, DiMe-C7: evidence for stability in rat brain and prolonged central actions A.S. Eison, S.D. Iversen, B.E.B. Sandberg, S.P. Watson, M.R. Hanley and L.L. Iversen, Science, 215 (1982) 188–190 (1982) (5)
Receptor regulation of phosphoinositide 3-hydroxykinase in the NG115-401L-C3 neuronal cell line: stimulation by insulin-like growth factor-I. (1993) (4)
Agonist‐Selective Protection of the Opioid Receptor‐Coupled G Proteins from Inactivation by 5′‐p‐fluorosulphonylbenzoyl Guanosine (1990) (4)
Double-stranded-RNA-activated protein kinase (PKR) regulates Ca2+ stores in Xenopus oocytes. (1998) (4)
Monoclonal antibodies to antidiuretic hormone. (1985) (3)
Analysis of receptor-coupled events in neuropeptide action using clonal cell lines. (1987) (3)
Comparison of Membrane Currents in Xenopus Oocytes in Response to Injection of Calcium Influx Factor (CIF) and Depletion of Intracellular Calcium Stores (2000) (3)
Inositol hexakisphosphate-membranes interactions: the role of metal ions. (1991) (2)
The identification of dansyl sarcosine and its occurrence in molluscs (1975) (2)
Cell to cell signalling: From experiments to theoretical models Edited by A. Goldbeter. ISBN 0-12-28796. price: $65.00 (1990) (2)
BIOCHEMISTRY OF SNAKE VENOM NEUROTOXINS AND THEIR APPLICATION TO THE STUDY OF THE SYNAPSE (1979) (2)
Substance P: Inactivation in CNS, Enzymatically Resistant Analogue and Development of "Brain Selective" Agonist (1983) (2)
Autoradiographic evidence for beta-adrenergic receptors on capsaicin-sensitive primary afferent terminals in rat spinal cord. (1987) (2)
The Effect of Short-term Muscle Fatigue on the Masseteric Silent Period (1983) (2)
Brutal times (1991) (1)
Preparing for the brain decade (1992) (1)
SUBSTANCE P:BINDING AND RECEPTOR-LINKED RESPONSES (1980) (1)
PERIPHERAL AND CENTRAL SUBSTANCE P BINDING SITES (1984) (1)
CONFORMATION OF THE NEUROTOXIC CROTOXIN COMPLEX AND ITS SUB-UNITS (1978) (1)
Apparent calcium-independent phorbol ester binding to protein kinase C. (1991) (1)
PEPTIDE RECEPTORS IN THE BRAIN AND PERIPHERY (1984) (1)
BIOCHEMICAL AND CELLULAR CHARACTERISATION OF MULTIPLE TACHYKININ RECEPTORS (1987) (1)
Metabolism of myo-inositol pentakisphosphates in mammalian brain. (1992) (1)
Communication within animal cells (1992) (0)
A monoclonal anti-idiotypic antibody to mu and delta opioid receptors. (1991) (0)
Cell sister (1989) (0)
Mixed tachykinins (1986) (0)
Phosphatidylinositol-3-phosphate and inositol phosphates in mitogenesis. (1990) (0)
Biochemistry of snake venom neurotoxins and their application to the study of synapse. [Neurotoxins isolated from venom of the Formosan banded krait] (1978) (0)
Pituitary astrocytes from the neural lobe of rats (1990) (0)
Alzheimer's disease. Amyloid precursor on the G(o) (1993) (0)
Muscarinic acetylcholine receptors and cyclic GMP in rat brain [proceedings]. (1977) (0)
DISCRIMINATION BETWEEN CHOLINERGIC RECEPTORS IN RAT BRAIN AND TORPEDO CALIFORNICA ELECTROPLAX BY BINDING OF SNAKE VENOM TOXINS (1981) (0)
Amylin and amylin agonists for the treatment of psychiatric diseases and disorders (2006) (0)
Cell regulation editorial overview (1992) (0)
Handbook for lipid research (Vol. 5): The phospholipases: Mosley Waite, Plenum Press, 1987. US$59.50 (xv + 332 pages) ISBN 0 306 42621 8 (1988) (0)
THE TOXICITY AND SPECTROSCOPIC PROPERTIES OP NEUROTOXINS FROM BUNGARUS MULTICINCTUS VENOM (1974) (0)
Amylin family peptides and methods for their preparation and use. (2005) (0)
Structure and mechanism of growth-regulatory peptide receptors (1990) (0)
Amylin and amylin agonists for the treatment of diseases and psychiatric disorders. (2006) (0)
Rats go with the (urine) flow (1997) (0)
PROPERTIES OF RADIO~LABELED a-BUNGAROTOXIN DERIVATIVES AND THEIR INTERACI'ION Willi NICOTINIC ACETYLCHOLINE RECEPTORS (2013) (0)
Tritiated Peptides. Part 12. Synthesis and Biological Activity of [4-3H-Phe8]Substance P. (1983) (0)
Proto-Oncogenes in the Nervous System Review (1988) (0)
Table of Contents (1987) (0)
Substance P-Stimulated Phosphatidylinositol Breakdown in Guinea Pig Ileum (1984) (0)
ANALOGS OF OMEGA-3 PUFAs DERIVED LIPID MEDIATORS AND METHOD OF USE (2003) (0)
Nerve centres (1994) (0)
Biochemical Pharmacology of Substance P Receptors (1984) (0)
Peptides of amylin family, to processes for their preparation and use (2005) (0)
PROPERTIES OF RADIO-LABELLED O -BUNGAROTOXIN DERIVATIVES AND THEIR INTERACTION WITH NICOTINIC ACETYLCHOLINE RECEPTORS (2013) (0)
Perturbation of calcium signalling by the neurotoxic tumour promoter, thapsigargin (1995) (0)

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What Schools Are Affiliated With Michael R. Hanley?

Michael R. Hanley is affiliated with the following schools:

Yale University