Michael R. Hanley
#154,295
Most Influential Person Now
Michael R. Hanley's AcademicInfluence.com Rankings
Michael R. Hanleymedical Degrees
Medical
#3006
World Rank
#3455
Historical Rank
Pharmacology
#348
World Rank
#399
Historical Rank

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Medical
Michael R. Hanley's Degrees
- PhD Pharmacology University of California, San Diego
- Bachelors Pharmacy University of California, San Francisco
Why Is Michael R. Hanley Influential?
(Suggest an Edit or Addition)Michael R. Hanley's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase. (1990) (3014)
- Lithium amplifies agonist-dependent phosphatidylinositol responses in brain and salivary glands. (1982) (1983)
- Thapsigargin inhibits the sarcoplasmic or endoplasmic reticulum Ca-ATPase family of calcium pumps. (1991) (1198)
- Neural and developmental actions of lithium: A unifying hypothesis (1989) (999)
- The mas oncogene encodes an angiotensin receptor (1988) (368)
- A novel tumour promoter, thapsigargin, transiently increases cytoplasmic free Ca2+ without generation of inositol phosphates in NG115-401L neuronal cells. (1988) (302)
- Thapsigargin , a tumor promoter , discharges intracellular Ca 2 + stores by specific inhibition of the endoplasmic reticulum Ca 2 +-ATPase ( hepatocyte / microsome / calcium pump ) (207)
- HHV8-encoded vMIP-I Selectively Engages Chemokine Receptor CCR8 (1999) (201)
- Development of macroglial cells in rat cerebellum. I. Use of antibodies to follow earlyin vivo development and migration of oligodendrocytes (1988) (184)
- Purification and characterisation of a membrane-bound substance-P-degrading enzyme from human brain. (1981) (162)
- Occurrence and extracellular actions of inositol pentakis- and hexakisphosphate in mammalian brain (1987) (161)
- Diverse molecular provocation of programmed cell death. (1996) (148)
- Thapsigargin, a novel molecular probe for studying intracellular calcium release and storage (1989) (146)
- Similar effects of substance P and related peptides on salivation and on phosphatidylinositol turnover in rat salivary glands. (1980) (146)
- Tissue selectivity of substance P alkyl esters: suggesting multiple receptors. (1983) (137)
- Metabolism and biological activities of inositol pentakisphosphate and inositol hexakisphosphate. (1995) (134)
- Specific binding of 3H-substance P to rat brain membranes (1980) (133)
- A vasopressin-like peptide in the mammalian sympathetic nervous system (1984) (132)
- Thapsigargin, a novel molecular probe for studying intracellular calcium release and storage (2005) (122)
- Calcium influx factor is synthesized by yeast and mammalian cells depleted of organellar calcium stores. (1999) (114)
- Receptor coupled events in bradykinin action: rapid production of inositol phosphates and regulation of cytosolic free Ca2+ in a neural cell line. (1987) (110)
- Evidence for a kappa-opioid receptor on pituitary astrocytes: An autoradiographic study (1985) (105)
- Proto-oncogenes in the nervous system (1988) (94)
- Pharmacological tools for perturbing intracellular calcium storage. (1994) (89)
- Muscarinic cholinergic receptors in rat corpus striatum and regulation of guanosine cyclic 3',5'-monophosphate. (1978) (86)
- myo-inositol pentakisphosphates. Structure, biological occurrence and phosphorylation to myo-inositol hexakisphosphate. (1991) (86)
- Regulation of c-fos and c-jun protooncogene expression by the Ca(2+)-ATPase inhibitor thapsigargin. (1991) (80)
- Peptide sequencing using the combination of edman degradation, carboxypeptidase digestion and fast atom bombardment mass spectrometry. (1982) (77)
- Synthesis and biological properties of enzyme-resistant analogues of substance P. (1981) (77)
- Evaluation of Calcium Influx Factors from Stimulated Jurkat T-lymphocytes by Microinjection into Xenopus Oocytes(*) (1995) (76)
- Autoradiographic localization of mas proto-oncogene mRNA in adult rat brain using in situ hybridization (1990) (75)
- Pharmacological characterization of a receptor for calcitonin gene‐related peptide on rat, L6 myocytes (1992) (75)
- Inositol trisphosphate and thapsigargin discriminate endoplasmic reticulum stores of calcium in rat brain. (1990) (74)
- The possible existence of multiple receptors for substance P (1982) (70)
- Thapsigargin, but not caffeine, blocks the ability of thyrotropin-releasing hormone to release Ca2+ from an intracellular store in GH4C1 pituitary cells. (1990) (67)
- Substance P Receptors (1980) (60)
- Sticky fingers and CAAX boxes (1988) (59)
- Characterization of metal ion-induced [3H]inositol hexakisphosphate binding to rat cerebellar membranes. (1993) (56)
- Return of the magnificent seven (1987) (55)
- [3H]‐QUINUCLIDINYL BENZILATE BINDING TO MUSCARINIC RECEPTORS IN RAT BRAIN: COMPARISON OF RESULTS FROM INTACT BRAIN SLICES AND HOMOGENATES (1979) (54)
- Functional substance P receptors on a rat pancreatic acinar cell line (1985) (52)
- Functional characterization by heterologous expression of a novel cloned tachykinin peptide receptor. (1996) (51)
- Neural function: metabolism and actions of inositol metabolites in mammalian brain. (1988) (49)
- Enzymatic synthesis of acetylcholine by a serotonin-containing neurone from Helix (1974) (47)
- Growth factors: Neuropeptides as mitogens (1985) (47)
- Substance P and bombesin elevate cytosolic Ca2+ by different molecular mechanisms in a rat pancreatic acinar cell line. (1990) (46)
- Transformer and transducer (1987) (45)
- Thapsigargin, a new calcium‐dependent epithelial anion secretagogue (1989) (44)
- Substance P receptors in the nervous system and possible receptor subtypes. (1982) (44)
- Chromatographic Resolution of an Intracellular Calcium Influx Factor from Thapsigargin-activated Jurkat Cells (1995) (43)
- Stepping up the pressure (1992) (40)
- The lethality and spectroscopic properties of toxins from Bungarus multicinctus (Blyth) venom. (1975) (40)
- Neurotoxins of Bungarus multicinctus vernom. Purification and partial characterization. (1977) (40)
- Crotoxin effects on Torpedo californica cholinergic excitable vesicles and the role of its phospholipase A activity. (1978) (39)
- Phosphatidic acid and lysophosphatidic acid stimulate receptor-regulated membrane currents in the Xenopus laevis oocyte. (1992) (38)
- Radiolabeled alpha-bungarotoxin derivatives: kinetic interaction with nicotinic acetylcholine receptors. (1981) (37)
- Identification of a novel inflammatory stimulant of chondrocytes. Early events in cell activation by bradykinin receptors on pig articular chondrocytes. (1989) (37)
- Attenuation of agonist‐induced desensitization of the rat substance P receptor by progressive truncation of the C‐terminus (1994) (37)
- Phosphatidylinositol metabolism in cells transformed by polyomavirus middle T antigen (1990) (37)
- 17β-estradiol stimulates substance P receptor gene expression (1997) (35)
- Properties of radiolabeled alpha-bungarotoxin derivatives and their interaction with nicotinic acetylcholine receptors. (1978) (34)
- Improved Glucose Control and Reduced Body Weight in Rodents with Dual Mechanism of Action Peptide Hybrids (2013) (33)
- THE EFFECTS OF SUBSTANCE P AND RELATED PEPTIDES ON α‐AMYLASE RELEASE FROM RAT PAROTID GLAND SLICES (1981) (33)
- Autoradiographic localization of peripheral benzodiazepine, dihydroalprenolol and arginine vasopressin binding sites in the pituitaries of control, stalk transected and Brattleboro rats. (1986) (32)
- Substance P antagonists (1982) (31)
- Tumor promoter 12‐O‐tetradecanoylphorbol 13‐acetate inhibits mas/angiotensin receptor‐stimulated inositol phosphate production and intracellular Ca2+ elevation in the 401L‐C3 neuronal cell line (1989) (30)
- Attenuation of agonist-induced desensitization of the rat substance P receptor by microinjection of inositol pentakis-and hexakisphosphates in Xenopus laevis oocytes. (1994) (29)
- Neuronal degeneration induced by stereotaxic injection of β-bungarotoxin into rat brain (1979) (28)
- Coping with a growing family (1987) (28)
- Regulation of inositol trisphosphate-induced membrane currents in Xenopus oocytes by a Jurkat cell calcium influx factor. (1996) (26)
- A phosphoinositide-linked peptide response in astrocytes: Evidence for regional heterogeneity (1988) (24)
- Multiple modes of protein kinase C regulation and their significance in signalling. (1988) (24)
- Identification of a novel inositol phosphate recognition site: specific [3H]inositol hexakisphosphate binding to brain regions and cerebellar membranes. (1990) (24)
- The immunocytochemical localisation of ‘substance-P-degrading enzyme’ within the rat spinal cord (1987) (23)
- Efficient high-throughput discovery of large peptidic hormones and biomarkers. (2006) (22)
- The metabolism and functions of inositol pentakisphosphate and inositol hexakisphosphate. (1989) (22)
- The role of phospholipases and phospholipid-derived signals in cell activation. (1991) (22)
- Stimulation of adenylate cyclase by amylin in CHO-K1 cells. (1992) (20)
- Malignant transformation by G protein-coupled hormone receptors (1994) (20)
- Autoradiographic evidence for β-adrenergic receptors on capsaicin-sensitive primary afferent terminals in rat spinal cord (1987) (19)
- Conformation of the neurotoxin crotoxin complex and its subunits. (1979) (19)
- Changes in inositol lipids and phosphates after stimulation of the MAS-transfected NG115-401L-C3 cell line by mitogenic and non-mitogenic stimuli. (1990) (18)
- A monoclonal anti-idiotypic antibody to μ and δ opioid receptors (1991) (18)
- PEPTIDE REGULATORY FACTORS IN THE NERVOUS SYSTEM (1989) (18)
- Inducible receptors. (1997) (17)
- 17beta-estradiol stimulates substance P receptor gene expression. (1997) (17)
- L6 skeletal muscle cells have functional V1‐vasopressin receptors coupled to stimulated inositol phospholipid metabolism (1987) (17)
- Mitogenic neurotransmitters (1989) (17)
- Bradykinin stimulation of inositol phosphate and calcium responses in insensitive to pertussis toxin in NG115-401L neuronal cells. (1987) (16)
- Tritiated peptides. 12. Synthesis and biological activity of [4-3H-Phe8]substance P. (1982) (16)
- Evidence for multiple tachykinin receptor subtypes on the rabbit iris sphincter muscle. (1988) (15)
- Acetylcholine activity in an identified 5‐hydroxytryptamine containing neuron (1974) (15)
- Biochemical and Pharmacological Studies of Substance P Receptors (1982) (15)
- Synthesis and metabolic stability of a tritium‐labelled substance P analogue (1982) (14)
- Presence and actions of vasopressin-like peptides in the rabbit anterior uvea (1989) (13)
- Calcium influx factor (CIF) as a diffusible messenger for the activation of capacitative calcium entry in Xenopus oocytes. (1999) (12)
- Sympathetic denervation impairs agonist-stimulated phosphatidylinositol metabolism in rat parotid glands. (1983) (12)
- Capacitative calcium influx. (1998) (12)
- Effect of capsaicin on the rabbit urinary bladder. What is the function of sensory nerves that contain substance P? (1990) (12)
- The mas oncogene as a neural peptide receptor: expression, regulation and mechanism of action. (1990) (11)
- Substance K receptor: return of the magnificent seven. (1987) (10)
- A comparison of the release of substance P and some synthetic analogues from micropipettes by microiontophoresis or pressure (1983) (10)
- Amyloid precursor on the Go (1993) (10)
- Down‐regulation of phorbol diester binding to NG115‐401L neuronal cells is dependent on structure, concentration and time (1987) (10)
- Expression of the MAS proto-oncogene in the retinal pigment epithelium of the rhesus macaque. (1994) (10)
- Solubilization and characterization of substance P-binding sites from chick brain membranes. (1988) (10)
- Protein modification. Sticky fingers and CAAX boxes. (1988) (9)
- Molecular and Cell Biology of Angiotensin Receptors (1991) (9)
- The ras gene. Transformer and transducer. (1987) (9)
- Peptide receptors. Stepping up the pressure. (1992) (8)
- Protein kinase Cs. Coping with a growing family. (1987) (8)
- Messenger RNA localization and further characterisation of the putative tachykinin receptor NK4 (NK3B). (2001) (6)
- Molecular mechanisms of phospholipid signaling pathways in mammalian nerve cells. (1988) (6)
- Molecular Biology of Peptide and Glycoprotein Hormone Receptors (1992) (6)
- Inositol hexakisphosphate biosynthesis in mammalian brain: identification of a novel inositol pentakisphosphate kinase. (1990) (5)
- Inositol phospholipids and phosphates for investigation of intact cell phospholipase C substrates and products. (1991) (5)
- Stimulation of Ca(2+)-dependent membrane currents in Xenopus oocytes by microinjection of pyrimidine nucleotide-glucose conjugates. (1996) (5)
- Substance P analog, DiMe-C7: evidence for stability in rat brain and prolonged central actions A.S. Eison, S.D. Iversen, B.E.B. Sandberg, S.P. Watson, M.R. Hanley and L.L. Iversen, Science, 215 (1982) 188–190 (1982) (5)
- Receptor regulation of phosphoinositide 3-hydroxykinase in the NG115-401L-C3 neuronal cell line: stimulation by insulin-like growth factor-I. (1993) (4)
- Agonist‐Selective Protection of the Opioid Receptor‐Coupled G Proteins from Inactivation by 5′‐p‐fluorosulphonylbenzoyl Guanosine (1990) (4)
- Double-stranded-RNA-activated protein kinase (PKR) regulates Ca2+ stores in Xenopus oocytes. (1998) (4)
- Monoclonal antibodies to antidiuretic hormone. (1985) (3)
- Analysis of receptor-coupled events in neuropeptide action using clonal cell lines. (1987) (3)
- Comparison of Membrane Currents in Xenopus Oocytes in Response to Injection of Calcium Influx Factor (CIF) and Depletion of Intracellular Calcium Stores (2000) (3)
- Inositol hexakisphosphate-membranes interactions: the role of metal ions. (1991) (2)
- The identification of dansyl sarcosine and its occurrence in molluscs (1975) (2)
- Cell to cell signalling: From experiments to theoretical models Edited by A. Goldbeter. ISBN 0-12-28796. price: $65.00 (1990) (2)
- BIOCHEMISTRY OF SNAKE VENOM NEUROTOXINS AND THEIR APPLICATION TO THE STUDY OF THE SYNAPSE (1979) (2)
- Substance P: Inactivation in CNS, Enzymatically Resistant Analogue and Development of "Brain Selective" Agonist (1983) (2)
- Autoradiographic evidence for beta-adrenergic receptors on capsaicin-sensitive primary afferent terminals in rat spinal cord. (1987) (2)
- The Effect of Short-term Muscle Fatigue on the Masseteric Silent Period (1983) (2)
- Brutal times (1991) (1)
- Preparing for the brain decade (1992) (1)
- SUBSTANCE P:BINDING AND RECEPTOR-LINKED RESPONSES (1980) (1)
- PERIPHERAL AND CENTRAL SUBSTANCE P BINDING SITES (1984) (1)
- CONFORMATION OF THE NEUROTOXIC CROTOXIN COMPLEX AND ITS SUB-UNITS (1978) (1)
- Apparent calcium-independent phorbol ester binding to protein kinase C. (1991) (1)
- PEPTIDE RECEPTORS IN THE BRAIN AND PERIPHERY (1984) (1)
- BIOCHEMICAL AND CELLULAR CHARACTERISATION OF MULTIPLE TACHYKININ RECEPTORS (1987) (1)
- Metabolism of myo-inositol pentakisphosphates in mammalian brain. (1992) (1)
- Communication within animal cells (1992) (0)
- A monoclonal anti-idiotypic antibody to mu and delta opioid receptors. (1991) (0)
- Cell sister (1989) (0)
- Mixed tachykinins (1986) (0)
- Phosphatidylinositol-3-phosphate and inositol phosphates in mitogenesis. (1990) (0)
- Biochemistry of snake venom neurotoxins and their application to the study of synapse. [Neurotoxins isolated from venom of the Formosan banded krait] (1978) (0)
- Pituitary astrocytes from the neural lobe of rats (1990) (0)
- Alzheimer's disease. Amyloid precursor on the G(o) (1993) (0)
- Muscarinic acetylcholine receptors and cyclic GMP in rat brain [proceedings]. (1977) (0)
- DISCRIMINATION BETWEEN CHOLINERGIC RECEPTORS IN RAT BRAIN AND TORPEDO CALIFORNICA ELECTROPLAX BY BINDING OF SNAKE VENOM TOXINS (1981) (0)
- Amylin and amylin agonists for the treatment of psychiatric diseases and disorders (2006) (0)
- Cell regulation editorial overview (1992) (0)
- Handbook for lipid research (Vol. 5): The phospholipases: Mosley Waite, Plenum Press, 1987. US$59.50 (xv + 332 pages) ISBN 0 306 42621 8 (1988) (0)
- THE TOXICITY AND SPECTROSCOPIC PROPERTIES OP NEUROTOXINS FROM BUNGARUS MULTICINCTUS VENOM (1974) (0)
- Amylin family peptides and methods for their preparation and use. (2005) (0)
- Structure and mechanism of growth-regulatory peptide receptors (1990) (0)
- Amylin and amylin agonists for the treatment of diseases and psychiatric disorders. (2006) (0)
- Rats go with the (urine) flow (1997) (0)
- PROPERTIES OF RADIO~LABELED a-BUNGAROTOXIN DERIVATIVES AND THEIR INTERACI'ION Willi NICOTINIC ACETYLCHOLINE RECEPTORS (2013) (0)
- Tritiated Peptides. Part 12. Synthesis and Biological Activity of [4-3H-Phe8]Substance P. (1983) (0)
- Proto-Oncogenes in the Nervous System Review (1988) (0)
- Table of Contents (1987) (0)
- Substance P-Stimulated Phosphatidylinositol Breakdown in Guinea Pig Ileum (1984) (0)
- ANALOGS OF OMEGA-3 PUFAs DERIVED LIPID MEDIATORS AND METHOD OF USE (2003) (0)
- Nerve centres (1994) (0)
- Biochemical Pharmacology of Substance P Receptors (1984) (0)
- Peptides of amylin family, to processes for their preparation and use (2005) (0)
- PROPERTIES OF RADIO-LABELLED O -BUNGAROTOXIN DERIVATIVES AND THEIR INTERACTION WITH NICOTINIC ACETYLCHOLINE RECEPTORS (2013) (0)
- Perturbation of calcium signalling by the neurotoxic tumour promoter, thapsigargin (1995) (0)
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