Mark R. Haussler

Mark R. Haussler's AcademicInfluence.com Rankings

Mark R. Haussler

Biology

#7194

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#10076

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Molecular Biology

#804

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#824

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Biology

Mark R. Haussler's Degrees

PhD Molecular Biology University of California, Berkeley
Bachelors Biology University of California, Santa Cruz

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Mark R. Haussler's Published Works

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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

The Nuclear Vitamin D Receptor: Biological and Molecular Regulatory Properties Revealed (1998) (1415)
Vitamin D Receptor As an Intestinal Bile Acid Sensor (2002) (1023)
Cloning and expression of full-length cDNA encoding human vitamin D receptor. (1988) (904)
Estrogen binding, receptor mRNA, and biologic response in osteoblast-like osteosarcoma cells. (1988) (835)
Molecular Mechanisms of Vitamin D Action (2012) (596)
Vitamin D receptor (VDR)-mediated actions of 1α,25(OH)₂vitamin D₃: genomic and non-genomic mechanisms. (2011) (556)
Basic and clinical concepts related to vitamin D metabolism and action (second of two parts). (1977) (512)
Molecular cloning of complementary DNA encoding the avian receptor for vitamin D. (1987) (496)
Functionally relevant polymorphisms in the human nuclear vitamin D receptor gene (2001) (390)
The polymorphic N terminus in human vitamin D receptor isoforms influences transcriptional activity by modulating interaction with transcription factor IIB. (2000) (384)
1alpha,25-Dihydroxyvitamin D3 upregulates FGF23 gene expression in bone: the final link in a renal-gastrointestinal-skeletal axis that controls phosphate transport. (2005) (378)
Vitamin D receptors: nature and function. (1986) (354)
Identification and regulation of 1,25-dihydroxyvitamin D3 receptor activity and biosynthesis of 1,25-dihydroxyvitamin D3. Studies in cultured bovine aortic endothelial cells and human dermal capillaries. (1989) (345)
The vitamin D hormone and its nuclear receptor: molecular actions and disease states. (1997) (321)
Effects of retinoic acid (RA) on the growth and phenotypic expression of several human neuroblastoma cell lines. (1983) (306)
Vitamin D receptor: molecular signaling and actions of nutritional ligands in disease prevention. (2008) (303)
Molecular Nature of the Vitamin D Receptor and its Role in Regulation of Gene Expression (2001) (277)
Retinoid X receptors stimulate and 9-cis retinoic acid inhibits 1,25-dihydroxyvitamin D3-activated expression of the rat osteocalcin gene (1993) (266)
The role of 1 alpha, 25-dihydroxyvitamin D in the mediation of intestinal hyperabsorption of calcium in primary hyperparathyroidism and absorptive hypercalciuria. (1977) (261)
Radioligand receptor assay for 25-hydroxyvitamin D2/D3 and 1 alpha, 25-dihydroxyvitamin D2/D3. (1976) (234)
The association of a metabolite of vitamin D3 with intestinal mucosa chromatin in vivo. (1968) (228)
THE ASSAY OF 1α, 25‐DIHYDROXYVITAMIN D3: PHYSIOLOGIC AND PATHOLOGIC MODULATION OF CIRCULATING HORMONE LEVELS (1976) (214)
Human vitamin D receptor is selectively phosphorylated by protein kinase C on serine 51, a residue crucial to its trans-activation function. (1991) (210)
Physical and Functional Interaction between the Vitamin D Receptor and Hairless Corepressor, Two Proteins Required for Hair Cycling* (2003) (205)
1α,25-Dihydroxycholecalciferol Receptors in Intestine I. ASSOCIATION OF 1α,25-DIHYDROXYCHOLECALCIFEROL WITH INTESTINAL MUCOSA CHROMATIN (1974) (203)
1 Alpha,25-dihydroxycholecalciferol receptors in intestine. II. Temperature-dependent transfer of the hormone to chromatin via a specific cytosol receptor. (1974) (198)
Immunocytochemical localization of the 1,25-dihydroxyvitamin D3 receptor in target cells. (1988) (197)
Transcription factor TFIIB and the vitamin D receptor cooperatively activate ligand-dependent transcription. (1995) (196)
The pathophysiology of altered calcium metabolism in rhabdomyolysis-induced acute renal failure. Interactions of parathyroid hormone, 25-hydroxycholecalciferol, and 1,25-dihydroxycholecalciferol. (1981) (193)
Reduction of vitamin D hormone receptor mRNA levels in Alzheimer as compared to Huntington hippocampus: correlation with calbindin-28k mRNA levels. (1992) (193)
Steroid hormone receptors: Evolution, ligands, and molecular basis of biologic function (1999) (183)
Increased serum 1,25-dihydroxyvitamin D in idiopathic hypercalciuria. (1977) (181)
Experimental diabetes reduces circulating 1,25-dihydroxyvitamin D in the rat. (1977) (180)
Cytoplasmic and nuclear binding components for 1alpha25-dihydroxyvitamin D3 in chick parathyroid glands. (1975) (175)
Filter assay for 1alpha, 25-dihydroxyvitamin D3. Utilization of the hormone's target tissue chromatin receptor. (1974) (166)
Expression of 1,25-dihydroxyvitamin D3 receptors in normal and psoriatic skin. (1991) (163)
Vitamin D 3 -25-hydroxylase: tissue occurrence and apparent lack of regulation. (1973) (159)
1,25-Dihydroxyvitamin D3/VDR-mediated induction of FGF23 as well as transcriptional control of other bone anabolic and catabolic genes that orchestrate the regulation of phosphate and calcium mineral metabolism (2007) (157)
Evidence for early induction of calmodulin gene expression in lymphocytes undergoing glucocorticoid-mediated apoptosis. (1991) (156)
Vitamin D Receptor: Key Roles in Bone Mineral Pathophysiology, Molecular Mechanism of Action, and Novel Nutritional Ligands (2007) (155)
Radioreceptor Assay for 1α,25-Dihydroxyvitamin D3 (1974) (153)
Vitamin D receptor controls expression of the anti-aging klotho gene in mouse and human renal cells. (2011) (151)
Molecular biology of the vitamin D hormone. (1988) (151)
Influence of 1,25-dihydroxyvitamin D3 on cultured osteogenic sarcoma cells: correlation with the 1,25-dihydroxyvitamin D3 receptor. (1984) (148)
The nuclear vitamin D receptor controls the expression of genes encoding factors which feed the “Fountain of Youth” to mediate healthful aging (2010) (146)
Chromosomal Receptor for A Vitamin D Metabolite (1969) (144)
High-affinity androgen binding and androgenic regulation of alpha 1(I)-procollagen and transforming growth factor-beta steady state messenger ribonucleic acid levels in human osteoblast-like osteosarcoma cells. (1991) (143)
Specific binding of 1alpha,25-dihydroxycholecalciferol to nuclear components of chick intestine. (1975) (141)
Liganded VDR induces CYP3A4 in small intestinal and colon cancer cells via DR3 and ER6 vitamin D responsive elements. (2002) (140)
Stable expression of the calbindin-D28K complementary DNA interferes with the apoptotic pathway in lymphocytes. (1992) (134)
1,25-Dihydroxyvitamin D3 receptor-like macromolecule in rat osteogenic sarcoma cell lines. (1980) (132)
Biochemical evidence for 1,25-dihydroxyvitamin D receptor macromolecules in parathyroid, pancreatic, pituitary, and placental tissues. (1980) (130)
A rapidly acting metabolite of vitamin D3. (1971) (128)
Vitamin D receptors from patients with resistance to 1,25-dihydroxyvitamin D3: point mutations confer reduced transactivation in response to ligand and impaired interaction with the retinoid X receptor heterodimeric partner. (1996) (128)
The vitamin D-responsive element in the rat bone Gla protein gene is an imperfect direct repeat that cooperates with other cis-elements in 1,25-dihydroxyvitamin D3- mediated transcriptional activation. (1991) (128)
Plasma 1,25-dihydroxyvitamin D levels in patients receiving anticonvulsant drugs. (1977) (125)
Immunocytochemical determination of estrogen receptor, progesterone receptor, and 1,25-dihydroxyvitamin D3 receptor in breast cancer and relationship to prognosis. (1991) (123)
Evaluation of a role for 1,25-dihydroxyvitamin D3 in the pathogenesis and treatment of X-linked hypophosphatemic rickets and osteomalacia. (1980) (121)
1,25-Dihydroxycholecalciferol deficiency: the probable cause of hypocalcemia and metabolic bone disease in pseudohypoparathyroidism. (1976) (121)
Immunocytochemical detection of 1,25-dihydroxyvitamin D receptors in normal human tissues (1988) (120)
Phosphorylation of the human vitamin D receptor by protein kinase C. Biochemical and functional evaluation of the serine 51 recognition site. (1993) (115)
The role of vitamin D in the FGF23, klotho, and phosphate bone-kidney endocrine axis (2012) (115)
Heterodimeric DNA Binding by the Vitamin D Receptor and Retinoid X Receptors Is Enhanced by 1,25-Dihydroxyvitamin D3 and Inhibited by 9-cis-Retinoic Acid (1998) (111)
Curcumin: a novel nutritionally derived ligand of the vitamin D receptor with implications for colon cancer chemoprevention. (2010) (110)
Baculovirus-mediated expression of the human vitamin D receptor. Functional characterization, vitamin D response element interactions, and evidence for a receptor auxiliary factor. (1991) (108)
New understanding of the molecular mechanism of receptor-mediated genomic actions of the vitamin D hormone. (1995) (105)
Hypophosphatemic osteomalacia: association with prostatic carcinoma. (1980) (103)
Immunocytochemical detection of 1,25-dihydroxyvitamin D receptors in normal human tissues. (1987) (103)
1,25-Dihydroxyvitamin D3 receptors in parathyroid glands. Preliminary characterization of cytoplasmic and nuclear binding components. (1978) (103)
Circulating 1alpha,25-dihydroxyvitamin D in the chicken: enhancement by injection of prolactin and during egg laying. (1976) (101)
Phosphorylation of serine 208 in the human vitamin D receptor. The predominant amino acid phosphorylated by casein kinase II, in vitro, and identification as a significant phosphorylation site in intact cells. (1993) (101)
Calcinogenic factor in Solanum malacoxylon: evidence that it is 1,25-dihydroxyvitamin D3-glycoside. (1976) (100)
Cloning of a functional vitamin D receptor from the lamprey (Petromyzon marinus), an ancient vertebrate lacking a calcified skeleton and teeth. (2003) (99)
The C-terminal region of the vitamin D receptor is essential to form a complex with a receptor auxiliary factor required for high affinity binding to the vitamin D-responsive element. (1994) (97)
Human vitamin D receptor phosphorylation by casein kinase II at Ser-208 potentiates transcriptional activation. (1996) (97)
Serum and monoclonal antibodies against the chick intestinal receptor for 1,25-dihydroxyvitamin D3. Generation by a preparation enriched in a 64,000-dalton protein. (1983) (97)
The ovary: a target organ for 1,25-dihydroxyvitamin D3. (1983) (96)
Dynamic changes in circulating 1,25-dihydroxyvitamin D during reproduction in rats. (1979) (94)
Calcium and phosphorus deficiency in rats: effects on PTH and 1,25-dihydroxyvitamin D3. (1979) (93)
Specific high-affinity binding and biologic action of retinoic acid in human neuroblastoma cell lines. (1983) (93)
Purification of chicken intestinal receptor for 1,25-dihydroxyvitamin D. (1979) (87)
Evidence for the biologically active form of cholecalciferol in the intestine. (1970) (86)
Development of hybridomas secreting monoclonal antibodies to the chicken intestinal 1 alpha,25-dihydroxyvitamin D3 receptor. (1982) (85)
An improved radioreceptor assay for 1,25-dihydroxyvitamin D in human plasma. (1981) (85)
Mutations in the 1,25-Dihydroxyvitamin D3 Receptor Identifying C-terminal Amino Acids Required for Transcriptional Activation That Are Functionally Dissociated from Hormone Binding, Heterodimeric DNA Binding, and Interaction with Basal Transcription Factor IIB, in Vitro * (1997) (83)
Biological activity of 1alpha-hydroxycholecalciferol, a synthetic analog of the hormonal form of vitamin D3. (1973) (82)
Increased intestinal chromatin template activity. Influence of 1alpha,25-dihydroxyvitamin D3 and hormone-receptor complexes. (1976) (80)
1,25-Dihydroxyvitamin D3 receptors in rat kidney cytosol. (1979) (79)
Ultrastructural immunocytochemical localization of endogenous 1,25-dihydroxyvitamin D3 and its receptors in osteoblasts and osteocytes from neonatal mouse and rat calvaria. (1987) (76)
Novel nuclear localization signal between the two DNA‐binding zinc fingers in the human vitamin D receptor (1998) (75)
Vitamin D3--resistant fibroblasts have immunoassayable 1,25-dihydroxyvitamin D3 receptors. (1984) (74)
Avian and mammalian receptors for 1,25-dihydroxyvitamin D3: in vitro translation to characterize size and hormone-dependent regulation. (1987) (74)
Molecular and functional comparison of 1,25‐dihydroxyvitamin D3 and the novel vitamin D receptor ligand, lithocholic acid, in activating transcription of cytochrome P450 3A4 (2005) (72)
CYP24A1 and CYP27B1 polymorphisms modulate vitamin D metabolism in colon cancer cells. (2013) (72)
The metabolism of vitamin D 3 in the chick. (1972) (72)
Nuclear and cytoplasmic receptors for 1,25-dihydroxycholecalciferol in intestinal mucosa. (1973) (71)
Nuclear and cytoplasmic binding components for vitamin D metabolites. (1975) (70)
Immunocytochemical detection of 1,25-dihydroxyvitamin D3 receptor in breast cancer. (1987) (69)
lα,25-dihydroxyvitamin D3 receptor: competitive binding of vitamin D analogs (1973) (67)
Role of prolactin in vitamin D metabolism and calcium absorption during lactation in the rat. (1982) (67)
Optimal vitamin D spurs serotonin: 1,25-dihydroxyvitamin D represses serotonin reuptake transport (SERT) and degradation (MAO-A) gene expression in cultured rat serotonergic neuronal cell lines (2018) (66)
Vitamin D receptor ligands, adenomatous polyposis coli, and the vitamin D receptor FokI polymorphism collectively modulate β‐catenin activity in colon cancer cells (2010) (66)
A composite element binding the vitamin D receptor, retinoid X receptor alpha, and a member of the CTF/NF-1 family of transcription factors mediates the vitamin D responsiveness of the c-fos promoter (1996) (66)
Calcium metabolism during lactation: enhanced intestinal calcium absorption in vitamin D-deprived, hypocalcemic rats. (1981) (66)
Evidence for a 1,25-dihydroxyvitamin D3 receptor-like macromolecule in rat pituitary. (1980) (65)
A highly conserved region in the hormone-binding domain of the human vitamin D receptor contains residues vital for heterodimerization with retinoid X receptor and for transcriptional activation. (1995) (65)
Evidence for in vivo upregulation of the intestinal vitamin D receptor during dietary calcium restriction in the rat. (1988) (65)
Influence of dietary vitamin D3 on the circulating concentration of its active metabolites in the chick and rat. (1977) (64)
Control of mineral homeostasis during lactation: interrelationships of 25-hydroxyvitamin D, 24,25-dihydroxyvitamin D, 1,25-dihydroxyvitamin D, parathyroid hormone, calcitonin, prolactin, and estradiol. (1981) (64)
Distinct retinoid X receptor activation function-2 residues mediate transactivation in homodimeric and vitamin D receptor heterodimeric contexts. (2001) (62)
Nutritional effectiveness of 1,25-dihydroxycholecalciferol in preventing rickets in chicks. (1973) (62)
Genomic actions of 1,25-dihydroxyvitamin D3. (1995) (62)
Vitamin D: mode of action and biomedical applications. (2009) (62)
Chromosomal receptor for a vitamin D metabolite. (2009) (60)
1,25-Dihydroxyvitamin D3-glycoside: Identification of a calcinogenic principle of solanum malacoxylon (1976) (60)
Effect of metabolic acidosis in intestinal absorption of calcium and phosphorus. (1980) (58)
1Alpha-hydroxyvitamin D3. An analog of vitamin D which apparently acts by metabolism to 1alpha, 25-dihydroxyvitamin D3. (1974) (57)
Vitamin D3 induced alteration of microvillar membrane lipid composition. (1972) (57)
The subcellular distribution of physiological doses of vitamin D3 (1967) (56)
Association of 1,25-dihydroxyvitamin D3 with cultured 3T6 mouse fibroblasts. Cellular uptake and receptor-mediated migration to the nucleus. (1983) (56)
Influence of phosphate depletion on the biosynthesis and circulating level of 1alpha,25-dihydroxyvitamin D. (1977) (55)
New insight into the structure and functions of the vitamin D receptor. (1994) (55)
Effect of parathyroidectomy on serum 1 alpha,25-dihydroxyvitamin D and intestinal calcium absorption in primary hyperparathyroidism. (1979) (53)
Immunohistochemical detection of 1,25-dihydroxyvitamin D3 receptors and estrogen receptors by monoclonal antibodies: comparison of four immunoperoxidase methods. (1989) (52)
Retinoic acid-induced differentiation of human neuroblastoma: a cell variant system showing two distinct responses. (1986) (51)
Vitamin D metabolites in adolescents and young adults with cystic fibrosis: effects of sun and season. (1985) (50)
1,25-Dihydroxyvitamin D3 induces 25-hydroxyvitamin D3-24-hydroxylase in a cultured monkey kidney cell line (LLC-MK2) apparently deficient in the high affinity receptor for the hormone. (1984) (49)
Chicken intestinal receptor for 1,25-dihydroxyvitamin D3. Immunologic characterization and homogeneous isolation of a 60,000-dalton protein. (1987) (48)
Nuclear Vitamin D Receptor: Structure-Function, Molecular Control of Gene Transcription, and Novel Bioactions (2005) (47)
Effect of the menstrual cycle on calcium-regulating hormones in the normal young woman. (1980) (47)
1,25-Dihydroxyvitamin D3 Regulation of Fibroblast Growth Factor-23 Expression in Bone Cells: Evidence for Primary and Secondary Mechanisms Modulated by Leptin and Interleukin-6 (2013) (47)
Tumor-induced osteomalacia. Evidence of a surgically correctable alteration in vitamin D metabolism. (1981) (46)
cis-Retinoic acid stimulates the clonal growth of some myeloid leukemia cells in vitro. (1987) (45)
Normocalcemic pseudohypoparathyroidism. Association with normal vitamin D3 metabolism. (1979) (44)
Immunochemical detection of unique proteolytic fragments of the chick 1,25-dihydroxyvitamin D3 receptor. Distinct 20-kDa DNA-binding and 45-kDa hormone-binding species. (1987) (44)
Estrogen binding and estrogenic responses in normal human osteoblast‐like cells (1991) (44)
Rapid enhancement of chick intestinal DNA-dependent RNA polymerase II activity by 1 alpha, 25-dihydroxyvitamin D3, in vivo. (1974) (44)
Characterization of unique DNA-binding and transcriptional-activation functions in the carboxyl-terminal extension of the zinc finger region in the human vitamin D receptor. (1999) (42)
Isolation of baculovirus‐expressed human vitamin D receptor: DNA responsive element interactions and phosphorylation of the purified receptor (2002) (42)
Metabolic Effects of Diphosphonate in Primary Hyperparathyroidism (1977) (42)
Selective deficiency of 1,25-dihydroxycholecalciferol. A cause of isolated skeletal resistance to parathyroid hormone. (1977) (42)
The pathogenesis of infantile malignant osteopetrosis: bone mineral metabolism and complications in five infants. (1981) (42)
Resveratrol Potentiates Vitamin D and Nuclear Receptor Signaling (2015) (41)
1,25-Dihydroxyvitamin D3 Down-regulation of PHEX Gene Expression Is Mediated by Apparent Repression of a 110 kDa Transfactor That Binds to a Polyadenine Element in the Promoter* (2004) (41)
1,25-Dihydroxyvitamin D and Klotho: A Tale of Two Renal Hormones Coming of Age. (2016) (41)
Molecular and functional comparison of 1,25-dihydroxyvitamin D(3) and the novel vitamin D receptor ligand, lithocholic acid, in activating transcription of cytochrome P450 3A4. (2005) (40)
FGF23 gene regulation by 1,25-dihydroxyvitamin D: opposing effects in adipocytes and osteocytes. (2015) (39)
The T-box near the zinc fingers of the human vitamin D receptor is required for heterodimeric DNA binding and transactivation. (1995) (38)
Dietary restriction of calcium, phosphorus, and vitamin D elicits differential regulation of the mrnas for avian intestinal calbindin‐D28K and the 1,25‐dihydroxyvitamin D3 receptor (1992) (38)
Phosphorylation of the human 1,25-dihydroxyvitamin D3 receptor by cAMP-dependent protein kinase, in vitro, and in transfected COS-7 cells. (1993) (37)
Suppression of ANP gene transcription by liganded vitamin D receptor: involvement of specific receptor domains. (1998) (37)
Abnormal relationship between serum phosphate concentration and renal 25-hydroxycholecalciferol-1-alpha-hydroxylase activity in X-linked hypophosphatemic mice. (1986) (37)
Glucocorticoid receptor in clonal osteosarcoma cell lines: a novel system for investigating bone active hormones. (1980) (35)
Vitamin D Activity and Colorectal Neoplasia: A Pathway Approach to Epidemiologic Studies (2005) (34)
Immunoselection of cDNAs to avian intestinal calcium binding protein 28K and a novel calmodulin-like protein: assessment of mRNA regulation by the vitamin D hormone. (1987) (33)
Influence of estrogen on renal vitamin D hydroxylases and serum 1alpha,25-(OH)2D3 in chicks. (1978) (33)
The 1,25-dihydroxy-vitamin D3 receptor is phosphorylated in response to 1,25-dihydroxy-vitamin D3 and 22-oxacalcitriol in rat osteoblasts, and by casein kinase II, in vitro. (1993) (33)
Examination of the Potential Functional Role of Conserved Cysteine Residues in the Hormone Binding Domain of the Human 1,25-Dihydroxyvitamin D Receptor (*) (1996) (32)
Normal Vitamin D Receptor Concentration and Responsiveness to 1,25-Dihydroxyvitamin D3 in Skin Fibroblasts from Patients with Absorptive Hypercalciuria (1998) (32)
Postpartum resolution of hypocalcemia in a lactating hypoparathyroid patient. (1984) (31)
1,25-Dihydroxyvitamin D3 inhibits the clonogenic growth of transformed cells via its receptor. (1986) (31)
Affinity Labeling of the 1,25-Dihydroxyvitamin D Receptor (*) (1996) (30)
Inhibition of ligand induced promoter occupancy in vivo by a dominant negative RXR (1996) (30)
1 Alpha,25-dihydroxycholecalciferol receptors in intestine. I. Association of 1 alpha,25-dihydroxycholecalciferol with intestinal mucosa chromatin. (1974) (29)
Vitamin D receptor phosphorylation in transfected ROS 17/2.8 cells is localized to the N-terminal region of the hormone-binding domain. (1991) (29)
Metabolites and analogues of vitamin D. Which for what? (1982) (29)
EFFECT OF ORAL CONTRACEPTIVES ON PLASMA CLEARANCE (1975) (29)
Development of a radioligand immunoassay for 1,25-dihydroxycholecalciferol receptors utilizing monoclonal antibody. (1984) (28)
Studies on the 1alpha, 25-dihydroxycholecalciferol-like activity in a calcinogenic plant. Cestrum diurnum, in the chick. (1976) (28)
Receptor for 1,25-dihydroxyvitamin D3 in GH3 pituitary cells. (1982) (27)
lα-Hydroxyvitamin D3: A Synthetic Sterol Which is Highly Active in Preventing Rickets in the Chick 1 (1974) (26)
Nuclear vitamin D receptor: Natural ligands, molecular structure-function, and transcriptional control of vital genes (2011) (26)
Characterization of the metabolites of vitamin D 3 in the chick. (1972) (25)
Nuclear vitamin D receptor: structure - function, phosphorylation, and control of gene transcription. (1997) (24)
MOLECULAR ACTION OF 1,25‐DIHYDROXYVITAMIN D3: NEW CULTURED CELL MODELS * (1981) (23)
Further evidence for the 1,25-dihydroxyvitamin D-like activity of Solanum malacoxylon. (1976) (23)
Partial purification of the chick intestinal receptor for 1,25‐dihydroxy vitamin D by ion exchange and blue dextran–sepharose chromatography (1978) (22)
SIRT1 enzymatically potentiates 1,25-dihydroxyvitamin D3 signaling via vitamin D receptor deacetylation (2017) (22)
22 Marabou Symposium: the changing faces of vitamin D. (2008) (22)
1,25-Dihydroxyvitamin D in Male, Nonspawning Female, and Spawning Female Trout (1981) (21)
Phenotypic and functional analysis of 1,25-dihydroxyvitamin D3 receptor mediated modulation of the human myeloma cell line RPMI 8226. (1988) (21)
Receptor mediated genomic action of the 1,25(OH)2D3 hormone: Expression of the human vitamin D receptor in E. coli (1995) (21)
Increased circulating 1α,25 dihydroxyvitamin D3 in patients with primary hyperparathyroidism (1975) (21)
Analysis of hairless corepressor mutants to characterize molecular cooperation with the vitamin D receptor in promoting the mammalian hair cycle (2010) (21)
Serum 1,25-dihydroxyvitamin D in bone diseases. (1979) (21)
Phosphorylation of human vitamin D receptor serine-182 by PKA suppresses 1,25(OH)2D3-dependent transactivation. (2004) (20)
Scintillation autoradiographic localization of 1,25-dihydroxyvitamin D3 in chick intestine. (1979) (20)
Basic studies on the mechanism of action of vitamin D. (1969) (19)
Two basic amino acids C-terminal of the proximal box specify functional binding of the vitamin D receptor to its rat osteocalcin deoxyribonucleic acid-responsive element. (2003) (19)
Saturation analysis of cellular retinoid binding proteins: application to retinoic acid resistant human neuroblastoma cells and to human tumors. (1987) (18)
Control of late cornified envelope genes relevant to psoriasis risk: upregulation by 1,25-dihydroxyvitamin D3 and plant-derived delphinidin (2013) (18)
The isolation of purified nuclear and chromatin fractions from chick intestinal mucosa. (1969) (18)
Radioligand Receptor Assay for 25-Hydroxyvitamin D2/D3 and la,25-Dihydroxyvitamin D2/D3 APPLICATION TO HYPERVITAMINOSIS D MMu (17)
Basic and clinical concepts related to vitamin D metabolism and action (first of two parts). (1977) (17)
High pressure liquid chromatographic detection of intracellular retinoid binding proteins from cultured cell and tumor cytosols. (1983) (17)
Further evidence supporting the phosphate leak hypothesis of idiopathic hypercalciuria. (1978) (17)
1,25-Dihydroxyvitamin D3 enhances the growth of tumors in athymic mice inoculated with receptor rich osteosarcoma cells. (1986) (17)
Purified human vitamin D receptor overexpressed in E. coli and baculovirus systems does not bind 1,25-dihydroxyvitamin D3 hormone efficiently unless supplemented with a rat liver nuclear extract. (1993) (17)
A variant form of the 1,25-dihydroxyvitamin D3 receptor with low apparent hormone affinity in cultured monkey kidney cells (LLC-MK2). A model for tissue resistance to vitamin D. (1985) (16)
Regulation of late cornified envelope genes relevant to psoriasis risk by plant-derived cyanidin. (2014) (16)
1,25-Dihydroxyvitamin D 3 -induced Differentiation in a Human Promyelocytic Leukemia Cell Line (HL-60) : Receptor-mediated Maturation to Macrophage-like Cells (2002) (15)
Bioactive Dietary VDR Ligands Regulate Genes Encoding Biomarkers of Skin Repair That Are Associated with Risk for Psoriasis (2018) (14)
Vitamin D receptor-mediated control of Soggy, Wise, and Hairless gene expression in keratinocytes. (2014) (14)
Vitamin D Receptor Mediates a Myriad of Biological Actions Dependent on Its 1,25‐Dihydroxyvitamin D Ligand: Distinct Regulatory Themes Revealed by Induction of Klotho and Fibroblast Growth Factor‐23 (2020) (13)
Identification and quantitation of intracellular retinol and retinoic acid binding proteins in cultured cells. (1984) (13)
1Alpha,25-dihydroxyvitamin D3 receptor: competitive binding of vitamin D analogs. (1973) (13)
Radioreceptor assay for 1 alpha,25-dihydroxyvitamin D3. (1974) (12)
C-terminal proteolysis of the avian 1,25-dihydroxyvitamin D3 receptor. (1987) (12)
Circulating levels and function of 1,25-(OH)2D3 in lactation. (1983) (10)
Regulation of plasma 1α,25 dihydroxyvitamin D by calcium and phosphate (1975) (10)
Phosphorus administration in patients with profound hypophosphatemia. (1984) (9)
1,25-Dihydroxyvitamin D3: Mode of action in intestine and parathyroid glands, assay in humans and isolation of its glycoside fromSolanum malacoxylon (1976) (9)
1,25-Dihydroxyvitamin D3: mode of action in intestine and parathyroid glands, assay in humans and isolation of its glycoside from Solanum malacoxylon. (1977) (9)
Evaluation of a putative vitamin D response element in the avian calcium binding protein gene. (1992) (9)
Vitamin D: Metabolism, Actions, and Disease States (1982) (8)
1,25-Dihydroxyvitamin D3 does not up-regulate vitamin D receptor messenger ribonucleic acid levels in hypophosphatemic mice. (1992) (8)
[63] A sensitive radioreceptor assay for 1α,25-dihydroxyvitamin D in biological fluid (1980) (8)
1,25(OH)2D3‐dependent regulation of calbindin‐D28k mRNA requires ongoing protein synthesis in chick duodenal organ culture (1995) (8)
Retinoic acid-induced changes in epidermal growth factor binding and in biological responses mediated by phorbol ester tumor promoter. (1984) (8)
Receptor-positive resistance to 1,25-hydroxyvitamin D: A new cause of osteomalacia associated with impaired induction of 24-hydroxylase in fibroblasts (1982) (8)
Bone vitamin D-dependent calcium-binding protein is localized in chondrocytes of growth-plate cartilage (1986) (8)
Elevated serum levels of 1alpha, 25-dihydroxycholecalciferol in lactating rats. (1977) (7)
Biochemical evidence for a 170-kilodalton, AF-2-dependent vitamin D receptor/retinoid X receptor coactivator that is highly expressed in osteoblasts. (2000) (7)
Physiological importance of vitamin D metabolism. (1980) (7)
1,25-DIHYDROXYVITAMIN D3 RECEPTORS IN CANCER (1980) (7)
Two Basic Amino Acids C-terminal of the P-box Specify Functional Binding of the Vitamin D Receptor to its Rat Osteocalcin DNA Responsive Element (2003) (7)
Association between Circulating Vitamin D Metabolites and Fecal Bile Acid Concentrations (2016) (6)
[62] Characteristics and purification of the intestinal receptor for 1,25-dihydroxyvitamin D (1980) (5)
26 – Vitamin D: Metabolism, Drug Interactions and Therapeutic Applications in Humans (1978) (5)
1,25-dihydroxycholecalciferol in hypophosphataemic osteomalacia presenting in adults. (1978) (5)
Lack of effect of hypomagnesemia on elevated plasma 1,25-dihydroxycholecalciferol in acutely phosphate-deprived rats. (1978) (5)
1Alpha-hydroxyvitamin D3: a synthetic sterol which is highly active in preventing rickets in the chick. (1974) (5)
Pomegranate derivative urolithin A enhances vitamin D receptor signaling to amplify serotonin-related gene induction by 1,25-dihydroxyvitamin D (2020) (5)
Plasma 1,25 dihydroxyvitamin D levels in patients on anticonvulsant drugs (1976) (5)
Biological Activity of la-Hydroxycholecalciferol , A Synthetic Analog of the Hormonal Form of Vitamin D 3 ( 1 , 25-dihydroxycholecalciferol / calcium absorption / bone calcium resorption / metabolic bone disease ) (5)
Anticonvulsant therapy and vitamin D metabolism: evidence for different mechanisms for phenytoin and phenobarbital. (1980) (5)
Cytoplasmic and nuclear binding components for la , 25-dihydroxyvitamin D 3 in chick parathyroid glands ( vitamin D / receptors / parathyroid hormone ) (4)
[64] Use of chick kidney to enzymatically generate radiolabeled 1,25-dihydroxyvitamin D and other vitamin D metabolites (1980) (4)
Genomic actions of 1,25-dihydoxyvitamin D3 : Pleiotropic actions of vitamin D (1995) (4)
Affinity labeling of the 1 alpha,25-dihydroxyvitamin D3 receptor. (1996) (4)
Immunocytological localization of 1,25-dihydroxyvitamin D3-like molecules and their receptors in a calcium-transporting epithelium of a crustacean (1991) (4)
High performance liquid chromatography of the 1,25-dihydroxyvitamin D3 receptor: its application toward resolution of receptor-monoclonal antibody complexes. (1982) (4)
Biosynthesis, purification and receptor binding properties of high specific radioactivity 1 alpha, 24(R),25-trihydroxy-[26,27-methyl-3H]-vitamin D3. (1982) (4)
1,25-dihydroxyvitamin D3-receptors and responsiveness in established cell lines from mammalian kidney, breast and pituitary (1981) (3)
Radioreceptor assay of plasma lα,25 dihydroxy vitamin D3 in patients with chronic renal failure (1974) (3)
Modulation of Serotonin Synthesis, Reuptake, and Degradation by 1,25‐Dihydroxyvitamin D: Potential Relevance for Neuropsychiatric Disorders (2016) (3)
Vitamin D: Biochemistry and clinical applications (1977) (3)
Use of chick kidney to enzymatically generate radiolabeled 1,25-dihydroxyvitamin D and other vitamin D metabolites. (1980) (2)
1, 25-dihydroxyvitamin D3-glycoside: identification of a calcinogenic principle of Solanium malocoxylon. (1976) (2)
THE PATHOGENESIS OF INFANTILE MALIGNANT OSTEOPETROSIS (1981) (2)
Vitamin D Nutrient-Gene Interactions and Healthful Aging (2016) (2)
Affinity Labeling of the 1a,25-Dihydroxyvitamin D3 Receptor* (1996) (2)
Survey of vitamin D metabolite-binding components in rachitic chick tissues: Detection with high specific activity sterols (1979) (2)
The specific association of a vitamin D metabolite with the genome of its target organ, in vivo. (1969) (2)
1,25-Dihydroxyvitamin D3 receptors in space-flown vs. grounded control rat kidneys. (1985) (2)
A sensitive radioreceptor assay for 1 alpha, 25-dihydroxyvitamin D in biological fluids. (1980) (2)
Diabetes and vitamin D metabolism (1976) (2)
APPLICATION TO HYPERVITAMINOSIS D (1976) (2)
Human osteoblastic osteosarcoma cells exhibit androgen receptors and androgenic responses. (1990) (2)
Receptors for 1,25-Dihydroxyvitamin D3: Structural Comparisons and Recent Functional Insights (1987) (1)
Monoclonal antibodies as probes in the characterization of 1,25-dihydroxyvitamin D3 receptors. (1986) (1)
In vitro transcription and translation of the human 1,25-dihydroxyvitamin D3 receptor cDNA. (1990) (1)
Characteristics and purification of the intstinal receptor for 1,25-dihydroxyvitamin D. (1980) (1)
The Journal of Biological Chemistry, Volume 245, 1970: Evidence for the biologically active form of cholecalciferol in the intestine. (1991) (1)
Receptor-Mediated Action of the Vitamin D Hormone (1987) (1)
The nuclear vitamin D receptor: From clinical radioreceptor assay of the vitamin D hormone to genomics, proteomics and a novel ligand (2002) (1)
Introduction: Special Issue on Vitamin D Dedicated to the Memory of Anthony W Norman (2020) (1)
Gene regulation in osteoblastic cells by carboxylterminal PTH peptides: Effects of hPTH (53–84) in human osteoblastic SaOS-2 cells (1992) (1)
Molecular Mechanisms of Vitamin D Action (2012) (1)
Circulating vitamin D metabolites in the male and female trout (1979) (1)
1,25-Dihydroxyvitamin D3 receptors: altered functional domains are associated with cellular resistance to vitamin D3. (1986) (1)
The Putative Role of Resveratrol in SIRT-1 Mediated Modulation of the Vitamin D Pathway (2013) (0)
Cooperative Inhibition of Wnt/β‐Catenin Signaling by Klotho and Vitamin D: Implications for Chemoprevention (2018) (0)
Identification and quantitation of intracellular retinol and retinoic acid binding proteins in cultured cells. - eScholarship (1984) (0)
Radioreceptor assay of circulating 1α,25 dihydroxyvitamin D3 in patients with disorders of mineral metabolism (1975) (0)
Vitamin D Stimulates Serotonin Production via Induction of the Tryptophan Hydroxylase 2 Isoform in B14 Rat Medullary Neurons (2018) (0)
Nutraceuticals Derived From Pomegranate Selectively Enhance Vitamin D Receptor Signaling to Amplify Key Vitamin D Target Genes (2020) (0)
PROC.V INT.CONGR.ENDOCRINOLOGY, VOL.II: specificity of cytosolic and nuclear receptors and responses (1977) (0)
Effect of oral contraceptive therapy on vitamin-A blood levels vitamin-D3 and drug metabolism. (1974) (0)
mRNA expression of osteoblastic markers in normal human bone cells in culture (1992) (0)
Vitamin D Impacts Nrf‐2 Signaling and Antioxidation Pathways that Modulate Cellular Aging (2020) (0)
Rapid enhancement of intestinal DNA dependent RNA polymerase II activity by 1α,25 dihydroxyvitamin D3 in vivo (1974) (0)
Anthony W Norman, PhD, Biochemist, Mentor, Distinguished Professor, and Principal Steward of Vitamin D Science (1938–2019) (2019) (0)
Vitamin D and APC modulate molecular crosstalk between β-catenin/Wnt signaling and the vitamin D receptor in colon cancer cells (2007) (0)
Nuclear 1α,25 dihydroxyvitamin D3 receptors in intestine (1975) (0)
Development ofhybridomas secreting monoclonal antibodies tothe chicken intestinal la,25-dihydroxyv (1982) (0)
26 REGULATION OF FGF23 BY 1,25-DIHYDROXYVITAMIN D3: A SECONDARY MECHANISM INVOLVING HISTONE H4 ACETYLATION. (2007) (0)
1,25-Dihydroxyvitamin D3 Regulation of Fibroblast Growth Factor-23 Expression in Bone Cells: Evidence for Primary and Secondary Mechanisms Modulated by Leptin and Interleukin-6 (2012) (0)
of the c-fos promoter. factors mediates the vitamin D responsiveness member of the CTF/NF-1 family of transcription receptor, retinoid X receptor alpha, and a A composite element binding the vitamin D (2013) (0)
Tumor Suppressors Klotho and 1,25‐Dihydroxyvitamin D3 Cooperate via Synergistic Inhibition of Oncogenic Wnt/β‐Catenin Signaling (2016) (0)
Effect of oral contraceptives on drug and Vitamin D3 metabolism. (1974) (0)
Assay for 1α,25 dihydroxyvitamin D3 (1974) (0)
Molecular and Cellular Pathobiology CYP 24 A 1 and CYP 27 B 1 Polymorphisms Modulate Vitamin D Metabolism in Colon Cancer Cells (2013) (0)
Optimal vitamin D spurs serotonin: 1,25-dihydroxyvitamin D represses serotonin reuptake transport (SERT) and degradation (MAO-A) gene expression in cultured rat serotonergic neuronal cell lines (2018) (0)
The role of 1,25-dihydroxycholecalciferol (DHCC) in the pathogenesis and treatment of X-linked hypophosphatemic rickets (XLH) (1979) (0)
1,25-Dihydroxyvitamin D (1,25-(OH)2D) and parathyroid hormone (PTH) in calcium and phosphate homeostasis: biochemical, physiological and clinical aspects (1979) (0)
Circulating 1,25-dihydroxyvitamin D in health and disease: an update (1978) (0)
The Vitamin D Receptor As A Therapeutic Target In Oxidative Stress And Nrf‐2 Signaling: Role Of Vitamin D And Urolithin A (2021) (0)

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