Martin C. Rechsteiner
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Martin C. Rechsteinerbiology Degrees
Biology
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Molecular Biology
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Biochemistry
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Biology
Martin C. Rechsteiner's Degrees
- PhD Biochemistry University of California, San Francisco
- Bachelors Chemistry University of California, Berkeley
Why Is Martin C. Rechsteiner Influential?
(Suggest an Edit or Addition)Martin C. Rechsteiner's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Amino acid sequences common to rapidly degraded proteins: the PEST hypothesis. (1986) (2474)
- Recognition of the polyubiquitin proteolytic signal (2000) (1795)
- PEST sequences and regulation by proteolysis. (1996) (1654)
- A 26 S protease subunit that binds ubiquitin conjugates. (1994) (755)
- Purification of two high molecular weight proteases from rabbit reticulocyte lysate. (1987) (468)
- The multicatalytic and 26 S proteases. (1993) (389)
- Purification of an 11 S regulator of the multicatalytic protease. (1992) (383)
- Mobilizing the proteolytic machine: cell biological roles of proteasome activators and inhibitors. (2005) (382)
- Ubiquitin-mediated pathways for intracellular proteolysis. (1987) (329)
- Characterization of Two Polyubiquitin Binding Sites in the 26 S Protease Subunit 5a* (1998) (320)
- PA200, a nuclear proteasome activator involved in DNA repair (2002) (316)
- Subcellular localization of proteasomes and their regulatory complexes in mammalian cells. (2000) (296)
- Introduction of macromolecules into cultured mammalian cells by osmotic lysis of pinocytic vesicles (1982) (291)
- The proteasome activator 11 S REG (PA28) and class I antigen presentation. (2000) (273)
- MAD2 associates with the cyclosome/anaphase-promoting complex and inhibits its activity. (1997) (245)
- Surface hydrophobic residues of multiubiquitin chains essential for proteolytic targeting. (1996) (244)
- Ubiquitin-lysozyme conjugates. Identification and characterization of an ATP-dependent protease from rabbit reticulocyte lysates. (1986) (241)
- Intracellular Localization of Proteasomal Degradation of a Viral Antigen (1999) (231)
- Identification of the long ubiquitin extension as ribosomal protein S27a (1989) (221)
- Natural substrates of the Ubiquitin proteolytic pathway (1991) (219)
- Multiple forms of the 20 S multicatalytic and the 26 S ubiquitin/ATP-dependent proteases from rabbit reticulocyte lysate. (1992) (202)
- Molecular cloning and expression of a gamma-interferon-inducible activator of the multicatalytic protease. (1994) (180)
- PEST sequences are signals for rapid intracellular proteolysis. (1990) (166)
- Structure of the proteasome activator REGα (PA28α) (1997) (165)
- Characterization of Recombinant REGα, REGβ, and REGγ Proteasome Activators* (1997) (149)
- Subunit 4 of the 26 S protease is a member of a novel eukaryotic ATPase family. (1992) (149)
- Protein surveillance machinery in brains with spinocerebellar ataxia type 3: Redistribution and differential recruitment of 26S proteasome subunits and chaperones to neuronal intranuclear inclusions (2002) (145)
- Regulation of enzyme levels by proteolysis: the role of pest regions. (1988) (137)
- Arabidopsis MBP1 gene encodes a conserved ubiquitin recognition component of the 26S proteasome. (1996) (131)
- Microinjection of ubiquitin: changes in protein degradation in HeLa cells subjected to heat-shock (1987) (128)
- The hydrophobic effect contributes to polyubiquitin chain recognition. (1998) (114)
- Proteasome activator 11S REG or PA28: recombinant REG alpha/REG beta hetero-oligomers are heptamers. (1999) (112)
- The axial channel of the 20S proteasome opens upon binding of the PA200 activator. (2005) (107)
- Proteasome impairment does not contribute to pathogenesis in R6/2 Huntington's disease mice: exclusion of proteasome activator REGgamma as a therapeutic target. (2006) (107)
- Drosophila lactate dehydrogenase and alpha-glycerolphosphate dehydrogenase: distribution and change in activity during development. (1970) (101)
- Potential Immunocompetence of Proteolytic Fragments Produced by Proteasomes before Evolution of the Vertebrate Immune System (1997) (97)
- Microinjection of thymidine kinase and bovine serum albumin into mammalian cells by fusion with red blood cells (1975) (94)
- Identification of an activation region in the proteasome activator REGalpha. (1998) (94)
- Substrate specificity of the human proteasome. (2001) (93)
- Hsp90 Enhances Degradation of Oxidized Calmodulin by the 20 S Proteasome* (2004) (92)
- The C terminus of mouse ornithine decarboxylase confers rapid degradation on dihydrofolate reductase. Support for the pest hypothesis. (1991) (91)
- Inhibition of Ubiquitin-mediated Proteolysis by the Arabidopsis 26 S Protease Subunit S5a (*) (1995) (90)
- Effects of interferon gamma and major histocompatibility complex-encoded subunits on peptidase activities of human multicatalytic proteases. (1995) (89)
- Magnitude and significance of NAD turnover in human cell line D98/AH2 (1976) (89)
- Microinjection of the nonhistone chromosomal protein hmg1 into bovine fibroblasts and hela cells (1979) (87)
- Specific Interactions between ATPase Subunits of the 26 S Protease* (1997) (84)
- Molecular dissection of the 11S REG (PA28) proteasome activators. (2001) (82)
- Conjugation of ubiquitin to denatured hemoglobin is proportional to the rate of hemoglobin degradation in HeLa cells. (1982) (80)
- Ubiquitin-lysozyme conjugates. Purification and susceptibility to proteolysis. (1986) (78)
- Characterization of Mammalian Ecm29, a 26 S Proteasome-associated Protein That Localizes to the Nucleus and Membrane Vesicles* (2004) (77)
- Peptide sequencing identifies MSS1, a modulator of HIV Tat‐mediated transactivation, as subunit 7 of the 26 S protease (1993) (77)
- The selective degradation of injected proteins occurs principally in the cytosol rather than in lysosomes (1981) (75)
- A Protein Interaction Network for Ecm29 Links the 26 S Proteasome to Molecular Motors and Endosomal Components* (2010) (73)
- New HEAT-like repeat motifs in proteins regulating proteasome structure and function. (2004) (71)
- Structure of the proteasome activator REGalpha (PA28alpha). (1997) (69)
- Characterization of recombinant REGalpha, REGbeta, and REGgamma proteasome activators. (1997) (68)
- Molecular Cloning and Expression of a 26 S Protease Subunit Enriched in Dileucine Repeats (*) (1995) (68)
- Activation of the multicatalytic protease. The 11 S regulator and 20 S ATPase complexes contain distinct 30-kilodalton subunits. (1994) (68)
- Molecular cloning and expression of a multiubiquitin chain binding subunit of the human 26S protease (1996) (67)
- Ubiquitin-mediated degradation of histone H3 does not require the substrate-binding ubiquitin protein ligase, E3, or attachment of polyubiquitin chains. (1990) (66)
- Red cell-mediated microinjection of macromolecules into mammalian cells. (1978) (63)
- Mapping Subunit Contacts in the Regulatory Complex of the 26 S Proteasome (2000) (63)
- Nucleotidase Activities of the 26 S Proteasome and Its Regulatory Complex* (1996) (59)
- Out with the old, in with the new? Comparing methods for measuring protein degradation (2011) (59)
- Lysine 188 substitutions convert the pattern of proteasome activation by REGγ to that of REGs α and β (2001) (54)
- Uptake of proteins by red blood cells. (1975) (53)
- Microinjection of ubiquitin: intracellular distribution and metabolism in HeLa cells maintained under normal physiological conditions (1987) (51)
- The 26 S Proteasome (1998) (48)
- The pyridine nucleotide cycle. Studies in Escherichia coli and the human cell line D98/AH2. (1981) (48)
- Proteasomes Cleave at Multiple Sites within Polyglutamine Tracts (2008) (47)
- Degradation of microinjected proteins: Effects of lysosomotropic agents and inhibitors of autophagy (1983) (46)
- Degradation of proteins microinjected into cultured mammalian cells (1979) (46)
- A Proteasome Activator Subunit Binds Calcium (*) (1995) (46)
- Selective degradation of aggregate-prone CryAB mutants by HSPB1 is mediated by ubiquitin-proteasome pathways. (2010) (45)
- Subunits of the regulatory complex of the 26S protease (2004) (44)
- Human lymphoblast and erythrocyte multicatalytic proteases: differential peptidase activities and responses to the 11S regulator (1995) (43)
- Are Huntington's and polyglutamine-based ataxias proteasome storage diseases? (2003) (41)
- Intracellular distribution and degradation of immunoglobulin G and immunoglobulin G fragments injected into HeLa cells (1983) (40)
- Assembly of the regulatory complex of the 26S proteasome (1999) (39)
- Pyridine nucleotide metabolism in mammalian cells in culture (1973) (38)
- The biosynthesis and turnover of nicotinamide adenine dinucleotide in enucleated culture cells (1974) (38)
- Tat-binding protein 7 is a subunit of the 26S protease. (1994) (36)
- Effects of temperature on the degradation of proteins in rabbit reticulocyte lysates and after injection into HeLa cells. (1984) (36)
- The multicatalytic proteinase: a high-Mr endopeptidase. (1988) (34)
- Ubiquitin/ATP-Dependent Protease (1988) (34)
- Drosophila lactate dehydrogenase: partial purification and characterization. (1970) (33)
- The proteasome 11S regulator subunit REGα (PA28α) is a heptamer (1997) (32)
- Molecular cloning and expression of subunit 12: a non‐MCP and non‐ATPase subunit of the 26 S protease (1995) (31)
- The N Terminus of Antizyme Promotes Degradation of Heterologous Proteins (*) (1996) (30)
- Tertiary structural rearrangements upon oxidation of Methionine145 in calmodulin promotes targeted proteasomal degradation. (2006) (30)
- Ubiquitin metabolism in ts85 cells, a mouse carcinoma line that contains a thermolabile ubiquitin activating enzyme. (1990) (29)
- Regulatory features of multicatalytic and 26S proteases. (1996) (29)
- Proteasome Activation by REG Molecules Lacking Homolog-specific Inserts* (1998) (28)
- Ubiquitin metabolism in cycling Xenopus egg extracts. (1993) (28)
- Lysine 188 substitutions convert the pattern of proteasome activation by REGgamma to that of REGs alpha and beta. (2001) (28)
- The Proteasome Activator 11 S Regulator or PA28 (1998) (28)
- The proteasome activator 11 S REG or PA28: chimeras implicate carboxyl-terminal sequences in oligomerization and proteasome binding but not in the activation of specific proteasome catalytic subunits. (2000) (27)
- Comparative studies on microinjected high-mobility-group chromosomal proteins, HMG1 and HMG2 (1981) (25)
- Purification procedures determine the proteasome activation properties of REGγ (PA28γ) (2004) (25)
- Extended reading frame of a ubiquitin gene encodes a stable, conserved, basic protein. (1988) (23)
- Degradation of structurally characterized proteins injected into HeLa cells. Tests of hypotheses. (1988) (21)
- Dynamic behavior of histone H1 microinjected into HeLa cells (1986) (20)
- Degradation of structurally characterized proteins injected into HeLa cells. Effects of intracellular location and the involvement of lysosomes. (1988) (18)
- The degradation of guanidinated lysozyme in reticulocyte lysate. (1986) (18)
- Degradation of proteins microinjected into HeLa cells. The role of substrate flexibility. (1986) (17)
- Arginine-rich histones do not exchange between human and mouse chromosomes in hybrid cells (1980) (16)
- The turnover of tRNAs microinjected into animal cells. (1978) (16)
- Time of suppression of human rRNA genes in mouse-human hybrid cells. (1979) (16)
- Evidence for a physiologically active nicotinamide phosphoribosyltransferase in cultured human fibroblasts. (1982) (16)
- Degradation of structurally characterized proteins injected into HeLa cells. Basic measurements. (1988) (16)
- [4] Osmotic lysis of pinosomes (1987) (16)
- Proteolysis in heat-stressed HeLa cells. Stabilization of ubiquitin correlates with the loss of proline endopeptidase. (1989) (16)
- Pyridine nucleotide metabolism in mitotic cells (1975) (15)
- The proteasome 11S regulator subunit REG alpha (PA28 alpha) is a heptamer. (1997) (15)
- Effects of interferon γ and major histocompatibility complex-encoded subunits on peptidase activities of human multicatalytic proteases (1995) (15)
- Purification procedures determine the proteasome activation properties of REG gamma (PA28 gamma). (2004) (14)
- Microinjection studies on selective protein degradation: relationships between stability, structure, and location. (1986) (14)
- Characterization of Recombinant REGa, REGb, and REGg Proteasome Activators* (1997) (14)
- Purification and assay of proteasome activator PA200. (2005) (13)
- Depletion of the 26S Proteasome Adaptor Ecm29 Increases Toll-Like Receptor 3 Signaling (2013) (13)
- Protein Degradation: Ubiquitin and the Chemistry of Life (2005) (13)
- The isotopic antiglobulin assay: application to the study of hybrid cell membranes. (1971) (13)
- The 26S Proteasome (2008) (13)
- Synthesis of peptides as cloned ubiquitin extensions. (1989) (13)
- Ubiquitin-mediated proteolysis: an ideal pathway for systems biology analysis. (2004) (12)
- Ubiquitination of full‐length cyclin (1995) (12)
- Discrimination between ubiquitin‐dependent and ubiquitin‐independent proteolytic pathways by the 26S proteasome subunit 5a (1999) (12)
- The 19S Regulatory Complex of the 26S Proteasome (1998) (12)
- Relationship between the structure of chromosomal protein HMG1 and its accumulation in the cell nucleus. (1985) (11)
- On the relationship between the metabolic and thermodynamic stabilities of T4 lysozymes. Measurements in Escherichia coli. (1994) (11)
- Autoradiographic studies of pyridine nucleotide metabolism in human culture cells (1974) (10)
- Identification, molecular cloning, and characterization of subunit 11 of the human 26S proteasome (1999) (10)
- Transfer of Macromolecules Using Erythrocyte Ghosts (1982) (10)
- Protein Degradation: Cell Biology of the Ubiquitin-Proteasome System, Volume 3 (2007) (10)
- On the relationship between the metabolic and thermodynamic stabilities of T4 lysozymes. Measurements in eukaryotic cells. (1994) (10)
- PEST regions, proteolysis and cell cycle progression. (1989) (9)
- What determines the degradation rate of an injected protein? (1984) (9)
- Degradation of structurally characterized proteins injected into HeLa cells. Comparison with their stability in rabbit reticulocyte lysate. (1989) (9)
- Proteasomes and antigen presentation: evidence that a KEKE motif does not promote presentation of the class I epitope SIINFEKL. (2006) (9)
- Osmotic lysis of pinosomes. (1987) (9)
- Effects of nucleotides on assembly of the 26S proteasome and degradation of ubiquitin conjugates (1997) (8)
- Ubiquitin and the chemistry of life (2005) (8)
- Dynamic workspace monitoring (1994) (7)
- Comprar Protein Degradation: Vol. 4: The Ubiquitin Proteasome System and Disease | R. John Mayer | 9783527314362 | Wiley (2007) (7)
- Degradation rates and intracellular distributions of structurally characterized proteins injected into HeLa cells. (1985) (6)
- The Human Genome Project: misguided science policy. (1991) (6)
- MAD 2 associates with the cyclosome y anaphase-promoting complex and inhibits its activity ( mitotic checkpoint y spindle assembly checkpoint y cell cycle y mitosis (1997) (6)
- The 11S Proteasomal Activator REGγ Impacts Polyglutamine-Expanded Androgen Receptor Aggregation and Motor Neuron Viability through Distinct Mechanisms (2017) (6)
- Evidence that DNA replication is not regulated by ubiquitin-dependent proteolysis in Xenopus egg extract. (2003) (6)
- Proposed Role of a γ-Interferon Inducible Proteasome-Regulator in Antigen Presentation (1996) (5)
- Fast and precise 3D sensor insensitive to ambient lighting (1993) (4)
- Do myc, fos and E1A function as protein phosphatase inhibitors? (1987) (4)
- The use of ubiquitin-peptide extensions as protein kinase substrates. (1990) (4)
- Varshavsky's Contributions (2004) (4)
- Red cell-mediated microinjection. (1978) (4)
- Ubiquitin-RAS peptide extensions as substrates for farnesyl-protein transferase and carboxymethyltransferase. (1992) (4)
- Circular pancreatic trypsin inhibitor. A novel substrate for studies on intracellular proteolysis. (1989) (3)
- The ubiquitin-proteasome system and disease (2008) (3)
- Protein Degradation Series (2007) (2)
- High-sensitivity high-dynamic digital CMOS imager (2001) (2)
- The folly of the human genome project. (1990) (2)
- Multiple forms of the 26S proteasome-associated protein Ecm29 in the mouse brain (2006) (2)
- Influence of Amine Compounds on the Thermal Stability of Paper-Oil Insulation (1983) (2)
- Exploring the Limits of Vanilla CNN Architectures for Fine-Grained Vision-Based Vehicle Classification (2021) (2)
- Implementation aspects of a real time workspace monitoring system (1995) (2)
- Genome intermixing and sister chromatid exchange in newly-formed HeLa-3T3 Hybrid cells. (1983) (2)
- Comprar Protein Degradation Series: 4 Volume Set | R. John Mayer | 9783527318780 | Wiley (2007) (1)
- The distribution of pyridine nucleotides between nucleus and cytoplasm (1974) (1)
- Real time inverse stereo system for surveillance of dynamic safety envelopes (1997) (1)
- Red Cell-Mediated Microinjection Studies on Protein Degradation (1980) (1)
- RED CELL MICROINJECTION OF TRANSFER RNA MOLECULES (1976) (1)
- RBC-mediated microinjection of chromatin components into cultured mammalian cells. (1985) (1)
- The Human Genome Project: Mediocre Science, Terrible Science Policy (1990) (0)
- Clonage moleculaire et expression d'un activateur du proteasome inductible par l'interferon gamma (1994) (0)
- Cell biology of the ubiquitin-proteasome syatem (2006) (0)
- The proteasome 11 s regulator subunit REGa ( PA 28 a ) is a heptamer (2002) (0)
- Means for monitoring room (1999) (0)
- Microinjection studies on selective protein degradation relationships between stability structure and intracellular location (1986) (0)
- Methodes d'identification de composes possedant un potentiel therapeutique pour le traitement des troubles du systeme nerveux central induits par l'accumulation de proteines ou de peptides anormaux (2002) (0)
- Proposed role of a gamma-interferon inducible proteasome-regulator in antigen presentation. (1996) (0)
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