Mark S. Mooseker
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Why Is Mark S. Mooseker Influential?
(Suggest an Edit or Addition)Mark S. Mooseker's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Identification of ZO-1: a high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epithelia (1986) (1624)
- Myosin-V is a processive actin-based motor (1999) (785)
- Unconventional myosins in cell movement, membrane traffic, and signal transduction. (1998) (668)
- Organization of an actin filament-membrane complex. Filament polarity and membrane attachment in the microvilli of intestinal epithelial cells (1975) (572)
- Unconventional Myosins in Inner-Ear Sensory Epithelia (1997) (537)
- Organization, chemistry, and assembly of the cytoskeletal apparatus of the intestinal brush border. (1985) (515)
- The mouse Snell's waltzer deafness gene encodes an unconventional myosin required for structural integrity of inner ear hair cells (1995) (478)
- MICROTUBULES: EVIDENCE FOR 13 PROTOFILAMENTS (1973) (456)
- Brain myosin-V is a two-headed unconventional myosin with motor activity (1993) (422)
- Expression in cochlea and retina of myosin VIIa, the gene product defective in Usher syndrome type 1B. (1995) (420)
- Role of the S. typhimurium actin-binding protein SipA in bacterial internalization. (1999) (404)
- Myosin-V stepping kinetics: a molecular model for processivity. (2000) (387)
- Characterization of the enterocyte-like brush border cytoskeleton of the C2BBe clones of the human intestinal cell line, Caco-2. (1992) (377)
- Characterization of ZO-1, a protein component of the tight junction from mouse liver and Madin-Darby canine kidney cells (1988) (374)
- Myosins: tails (and heads) of functional diversity. (2005) (371)
- Myosin Drives Retrograde F-Actin Flow in Neuronal Growth Cones (1996) (368)
- Unconventional myosins. (1992) (365)
- Primary structure and cellular localization of chicken brain myosin-V (p190), an unconventional myosin with calmodulin light chains (1992) (341)
- Compartmentalization of the cell cortex by septins is required for maintenance of cell polarity in yeast. (2000) (326)
- THE POLYMERIZATION OF ACTIN: ITS ROLE IN THE GENERATION OF THE ACROSOMAL PROCESS OF CERTAIN ECHINODERM SPERM (1973) (324)
- A novel cytoskeletal structure involved in purse string wound closure and cell polarity maintenance (1993) (320)
- Direct measurement of actin polymerization rate constants by electron microscopy of actin filaments nucleated by isolated microvillus cores (1981) (282)
- Class V myosins. (2000) (280)
- A contractile activity that closes phagosomes in macrophages. (1999) (276)
- Drosophila singed, a fascin homolog, is required for actin bundle formation during oogenesis and bristle extension (1994) (265)
- Phylogenetic analysis of the myosin superfamily. (1993) (258)
- Tight junction structure and ZO-1 content are identical in two strains of Madin-Darby canine kidney cells which differ in transepithelial resistance (1988) (245)
- A role for myosin VI in postsynaptic structure and glutamate receptor endocytosis (2005) (225)
- Porcine myosin-VI: characterization of a new mammalian unconventional myosin (1994) (220)
- An invasion-associated Salmonella protein modulates the actin-bundling activity of plastin. (1999) (202)
- Function of Myosin-V in Filopodial Extension of Neuronal Growth Cones (1996) (186)
- Erythrocyte adducin: a calmodulin-regulated actin-bundling protein that stimulates spectrin-actin binding (1987) (181)
- Actin from Thyone sperm assembles on only one end of an actin filament: a behavior regulated by profilin (1983) (181)
- Myosin-1a is critical for normal brush border structure and composition. (2005) (178)
- The light chain composition of chicken brain myosin-Va: calmodulin, myosin-II essential light chains, and 8-kDa dynein light chain/PIN. (2000) (172)
- Shaping the intestinal brush border (2014) (171)
- TEDS rule: a molecular rationale for differential regulation of myosins by phosphorylation of the heavy chain head. (1995) (169)
- Regulation of microvillus structure: calcium-dependent solation and cross-linking of actin filaments in the microvilli of intestinal epithelial cells (1980) (162)
- Brush border motility. Microvillar contraction in triton-treated brush borders isolated from intestinal epithelium (1976) (152)
- Ca++-calmodulin-dependent phosphorylation of myosin, and its role in brush border contraction in vitro (1982) (147)
- Actin in the brush-border of epithelial cells of the chicken intestine. (1971) (145)
- Binding of brush border myosin I to phospholipid vesicles (1990) (144)
- Myosin 1E interacts with synaptojanin‐1 and dynamin and is involved in endocytosis (2007) (144)
- Mechanism of brush border contractility studied by the quick-freeze, deep-etch method (1983) (142)
- Vesicle-associated brain myosin-V can be activated to catalyze actin-based transport. (1998) (139)
- An in vitro model for the analysis of intestinal brush border assembly. I. Ultrastructural analysis of cell contact-induced brush border assembly in Caco-2BBe cells. (1993) (138)
- The Yeast Class V Myosins, Myo2p and Myo4p, Are Nonprocessive Actin-Based Motors (2001) (135)
- Direct measurement of critical concentrations and assembly rate constants at the two ends of an actin filament (1983) (134)
- An in vitro model for the analysis of intestinal brush border assembly. II. Changes in expression and localization of brush border proteins during cell contact-induced brush border assembly in Caco-2BBe cells. (1993) (130)
- Characterization and localization of myosin in the brush border of intestinal epithelial cells (1978) (128)
- ZO-1 mRNA and protein expression during tight junction assembly in Caco- 2 cells (1989) (127)
- Molecular cloning and domain structure of human myosin-VIIa, the gene product defective in Usher syndrome 1B. (1996) (126)
- MYO1A (brush border myosin I) dynamics in the brush border of LLC-PK1-CL4 cells. (2002) (126)
- Effects of shaker-1 mutations on myosin-VIIa protein and mRNA expression. (1997) (122)
- Role of actin and Myo2p in polarized secretion and growth of Saccharomyces cerevisiae. (2000) (120)
- Enzymatic Characterization and Functional Domain Mapping of Brain Myosin-V* (1996) (119)
- Brush-border calmodulin. A major component of the isolated microvillus core (1980) (117)
- Assembly of the intestinal brush border: appearance and redistribution of microvillar core proteins in developing chick enterocytes (1987) (116)
- Myosin VIIA mutation screening in 189 Usher syndrome type 1 patients. (1996) (115)
- Biochemical and immunological characterization of p190-calmodulin complex from vertebrate brain: a novel calmodulin-binding myosin (1992) (114)
- The Abl-related gene (Arg) nonreceptor tyrosine kinase uses two F-actin-binding domains to bundle F-actin (2001) (114)
- The Abl-related gene (Arg) requires its F-actin–microtubule cross-linking activity to regulate lamellipodial dynamics during fibroblast adhesion (2004) (112)
- Molecular genetic dissection of mouse unconventional myosin-VA: tail region mutations. (1998) (110)
- Human myosin-IXb, an unconventional myosin with a chimerin-like rho/rac GTPase-activating protein domain in its tail. (1996) (109)
- Identification and overlapping expression of multiple unconventional myosin genes in vertebrate cell types. (1994) (108)
- ZO-1 and cingulin: tight junction proteins with distinct identities and localizations. (1989) (108)
- Phosphorylation of the tight-junction protein ZO-1 in two strains of Madin-Darby canine kidney cells which differ in transepithelial resistance. (1989) (108)
- Functional diversity among spectrin isoforms. (1989) (106)
- Localization of villin, a cytoskeletal protein specific to microvilli, in human ileum and colon and in colonic neoplasms. (1988) (106)
- Human myosin-IXb is a mechanochemically active motor and a GAP for rho. (1998) (106)
- The 110-kD protein-calmodulin complex of the intestinal microvillus is an actin-activated MgATPase (1987) (106)
- Modulation of Cell Adhesion and Motility in the Immune System by Myo1f (2006) (99)
- The 110-kD protein-calmodulin complex of the intestinal microvillus (brush border myosin I) is a mechanoenzyme (1989) (98)
- Cytochalasin B slows but does not prevent monomer addition at the barbed end of the actin filament (1986) (97)
- Characterization of the 110-kdalton actin-calmodulin-, and membrane- binding protein from microvilli of intestinal epithelial cells (1983) (97)
- Disruption of Myosin 1e promotes podocyte injury. (2009) (95)
- Nucleated polymerization of actin from the membrane-associated ends of microvillar filaments in the intestinal brush border (1982) (94)
- Multiple unconventional myosin domains of the intestinal brush border cytoskeleton. (1994) (93)
- Myosin-IXb Is a Single-headed and Processive Motor* (2002) (89)
- Brush border cytoskeleton and integration of cellular functions (1984) (86)
- Calcium-calmodulin and regulation of brush border myosin-I MgATPase and mechanochemistry (1993) (85)
- Different calcium dependence of the capping and cutting activities of villin. (1986) (84)
- Differential regulation of skeletal muscle myosin-II and brush border myosin-I enzymology and mechanochemistry by bacterially produced tropomyosin isoforms. (1994) (84)
- Myosin at work: motor adaptations for a variety of cellular functions. (2007) (84)
- Isolation and reactivation of the axostyle. Evidence for a dynein-like ATPase in the axostyle. (1973) (83)
- The tail of a yeast class V myosin, myo2p, functions as a localization domain. (1999) (82)
- Partial deduced sequence of the 110-kD-calmodulin complex of the avian intestinal microvillus shows that this mechanoenzyme is a member of the myosin I family (1989) (81)
- A role for myosin-1A in the localization of a brush border disaccharidase (2004) (81)
- Effect of villin on the kinetics of actin polymerization. (1984) (80)
- 6 Assembly of the Intestinal Brush Border Cytoskeleton (1992) (79)
- Mapping of unconventional myosins in mouse and human. (1996) (76)
- Actin filament-membrane attachment: are membrane particles involved? (1976) (76)
- Direct electron microscopic visualization of barbed end capping and filament cutting by intestinal microvillar 95-kdalton protein (villin): a new actin assembly assay using the limulus acrosomal process (1983) (74)
- Drosophila quail, a villin-related protein, bundles actin filaments in apoptotic nurse cells. (1999) (72)
- Molecular motors, membrane movements and physiology: emerging roles for myosins. (1995) (71)
- Myosin-I nomenclature (2001) (70)
- Myosin drives retrograde F-actin flow in neuronal growth cones. (1997) (69)
- Myosin-Va binds to and mechanochemically couples microtubules to actin filaments. (2003) (66)
- Localization of unconventional myosins V and VI in neuronal growth cones. (2000) (66)
- Role of myosin in terminal web contraction in isolated intestinal epithelial brush borders (1985) (65)
- Actin binding proteins of the brush border (1983) (63)
- Brush border Myosin Ia has tumor suppressor activity in the intestine (2012) (61)
- Myosin-VIIb, a novel unconventional myosin, is a constituent of microvilli in transporting epithelia. (2001) (60)
- Structural and immunological characterization of the myosin-like 110-kD subunit of the intestinal microvillar 110K-calmodulin complex: evidence for discrete myosin head and calmodulin-binding domains (1988) (59)
- Studies on the spectrin-like protein from the intestinal brush border, TW 260/240, and characterization of its interaction with the cytoskeleton and actin (1984) (58)
- In vitro motility of immunoadsorbed brain myosin-V using a Limulus acrosomal process and optical tweezer-based assay. (1995) (58)
- The actin-related proteins. (1996) (56)
- Identification and overlapping expression of multiple unconventional myosin genes in vertebrate cell types. (1994) (56)
- The molecular cloning and characterization of Drosophila melanogaster myosin-IA and myosin-IB. (1994) (55)
- Assembly of the intestinal brush border cytoskeleton. (1992) (55)
- Expression of myosin VI within the early endocytic pathway in adult and developing proximal tubules. (2002) (54)
- An actin-related protein in Drosophila colocalizes with heterochromatin protein 1 in pericentric heterochromatin. (1997) (54)
- Assembly of the brush border cytoskeleton: changes in the distribution of microvillar core proteins during enterocyte differentiation in adult chicken intestine. (1990) (53)
- Characterization of intestinal microvillar membrane disks: detergent- resistant membrane sheets enriched in associated brush border myosin I (110K-calmodulin) (1989) (53)
- Molecular Cloning and Domain Structure of Human Myosin-VIIa , the Gene Product Defective in Usher Syndrome 1 B (1996) (52)
- Cloning and mRNA expression of human unconventional myosin-IC. A homologue of amoeboid myosins-I with a single IQ motif and an SH3 domain. (1994) (52)
- Characterization of myosin-IA and myosin-IB, two unconventional myosins associated with the Drosophila brush border cytoskeleton. (1995) (52)
- Human brush border myosin-I and myosin-Ic expression in human intestine and Caco-2BBe cells. (1998) (51)
- α-AP-2 Directs Myosin VI-dependent Endocytosis of Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channels in the Intestine* (2010) (51)
- The growing family of myosin motors and their role in neurons and sensory cells (1997) (49)
- Calcium dependence of villin-induced actin depolymerization. (1984) (49)
- The brush border of intestinal epithelium: a model system for analysis of cell-surface architecture and motility. (1982) (49)
- Cytoskeletal proteins of the rat kidney proximal tubule brush border. (1986) (47)
- Vertebrate Unconventional Myosins* (1996) (47)
- Localization of capping protein in chicken epithelial cells by immunofluorescence and biochemical fractionation (1992) (47)
- Beta spectrin bestows protein 4.1 sensitivity on spectrin-actin interactions (1987) (46)
- Myosin VI is required for maintenance of brush border structure, composition, and membrane trafficking functions in the intestinal epithelial cell (2012) (45)
- Membrane-cytoskeletal crosstalk mediated by myosin-I regulates adhesion turnover during phagocytosis (2019) (45)
- Unconventional myosins. (1995) (44)
- Mechanisms of cytoskeletal regulation: modulation of membrane affinity in avian brush border and erythrocyte spectrins (1985) (43)
- Native Myosin-IXb is a plus-, not a minus-end-directed motor (2003) (43)
- A role for myosin IXb, a motor–RhoGAP chimera, in epithelial wound healing and tight junction regulation (2012) (41)
- The genomic structure of the gene defective in Usher syndrome type Ib (MYO7A). (1997) (41)
- Characterization of intestinal brush border cytoskeletal proteins of normal and neoplastic human epithelial cells. A comparison with the avian brush border. (1987) (40)
- Drosophila myosin V is required for larval development and spermatid individualization. (2005) (40)
- A multitude of myosins (1993) (39)
- The Tail Domain of Myosin Va Modulates Actin Binding to One Head* (2006) (39)
- The cytoskeleton of the intestinal epithelium: Components, assembly, and dynamic rearrangements (1996) (38)
- Effects of actin filament cross-linking and filament length on actin- myosin interaction (1985) (37)
- Molecular genetic dissection of mouse unconventional myosin-VA: head region mutations. (1998) (36)
- Contributions of the β‐subunit to spectrin structure and function (1989) (36)
- Chapter 3 Structural and Functional Dissection of a Membrane-Bound Mechanoenzyme: Brush Border Myosin I (1991) (35)
- Cell polarity protein Spa2P associates with proteins involved in actin function in Saccharomyces cerevisiae. (2005) (33)
- Altered renal proximal tubular endocytosis and histology in mice lacking myosin‐VI (2010) (32)
- Myosin-V motility: these levers were made for walking. (2003) (32)
- High Affinity Binding of Brain Myosin-Va to F-actin Induced by Calcium in the Presence of ATP* (2001) (32)
- Myo2p, a class V myosin in budding yeast, associates with a large ribonucleic acid-protein complex that contains mRNAs and subunits of the RNA-processing body. (2008) (32)
- Roles for Drosophila melanogaster myosin IB in maintenance of enterocyte brush-border structure and resistance to the bacterial pathogen Pseudomonas entomophila. (2007) (31)
- The molecular architecture of an insect midgut brush border cytoskeleton. (1992) (31)
- Myosin Id is required for planar cell polarity in ciliated tracheal and ependymal epithelial cells (2015) (30)
- Regulation of contractility, cytoskeletal structure, and filament assembly in the brush border of intestinal epithelial cells. (1982) (30)
- Hepatic immunohistochemical localization of the tight junction protein ZO-1 in rat models of cholestasis. (1989) (30)
- The mouse neurological mutant flailer expresses a novel hybrid gene derived by exon shuffling between Gnb5 and Myo5a. (2000) (26)
- Studies of muscle proteins in embryonic myocardial cells of cardiac lethal mutant mexican axolotls (Ambystoma mexicanum) by use of heavy meromyosin binding and sodium dodecyl sulfate polyacrylamide gel electrophoresis (1976) (25)
- Identification of a divergent actin-related protein in Drosophila. (1994) (25)
- In vitro motilities of the unconventional myosins, brush border myosin-I, and chick brain myosin-V exhibit assay-dependent differences in velocity. (1993) (25)
- Calcium and the regulation of cytoskeletal assembly, structure and contractility. (1986) (24)
- Brush border myosin Ia inactivation in gastric but not endometrial tumors (2013) (24)
- Brush-border alpha-actinin? Comparison of two proteins of the microvillus core with alpha-actinin by two-dimensional peptide mapping (1980) (24)
- Structural and compositional analysis of early stages in microvillus assembly in the enterocyte of the chick embryo. (1990) (23)
- Cloning of a secretory gelsolin from Drosophila melanogaster. (1993) (22)
- Analysis of cytoskeletal proteins and Ca2+-dependent regulation of structure in intestinal brush borders from rachitic chicks. (1982) (22)
- Assessment of myosin II, Va, VI and VIIa loss of function on endocytosis and endocytic vesicle motility in bone marrow-derived dendritic cells. (2007) (22)
- The Structural And Functional Diversity Of The Myosin Family Of Actin-Based Molecular Motors (2008) (22)
- Kinetics of actin elongation and depolymerization at the pointed end. (1987) (21)
- Actin-binding membrane proteins identified by F-actin blot overlays. (1997) (20)
- Myosin-1 a Is Critical for Normal Brush Border Structure and Composition (2008) (20)
- Regulation of cytoskeletal structure and contractility in the brush border. (1983) (19)
- Effects of villin on the polymerization and subunit exchange of actin. (1983) (18)
- Characterization of villin from the intestinal brush border of the rat, and comparative analysis with avian villin. (1988) (18)
- Cloning and characterization of mouse brush border myosin-I in adult and embryonic intestine. (1999) (18)
- Nucleation of actin polymerization by villin and elongation at subcritical monomer concentration. (1987) (18)
- Keeping out the rain (1993) (18)
- Ordering the membrane-cytoskeleton trilayer (1991) (17)
- Myosin VI and cardiomyopathy: Left ventricular hypertrophy, fibrosis, and both cardiac and pulmonary vascular endothelial cell defects in the Snell's waltzer mouse (2015) (15)
- A domain of synapsin I involved with actin bundling shares immunologic cross‐reactivity with villin (1988) (15)
- Reevaluation of the hydrophobic nature of the 110‐kD calmodulin‐, actin‐, and membrane‐binding protein of the intestinal microvillus (1986) (14)
- Actin assembly and filament cross-linking in the presence of TW 260/240, the tissue-specific spectrin of the chicken intestinal brush border. (1985) (13)
- Restoration of cytoskeletal and membrane tethering defects but not defects in membrane trafficking in the intestinal brush border of mice lacking both myosin Ia and myosin VI (2015) (11)
- Erratum: Molecular genetic dissection of mouse unconventional myosin- VA: Tail region mutations (Genetics (April 1998) 148 (1963-1972)) (1998) (11)
- Myosin linkage strengthened (1989) (7)
- The cytoskeletal apparatus of the intestinal brush border. (1984) (7)
- Contributions of the beta-subunit to spectrin structure and function. (1989) (7)
- ISOLATION AND REACTIVATION OF THE AXOSTYLE (1973) (6)
- The Mechanism of Actin-Filament Assembly and Cross-Linking (1982) (6)
- Molecular motors. Keeping out the rain. (1993) (5)
- Vertebrate unconventional myosins. (1996) (4)
- Erratum: Identification and overlapping expression of multiple unconventional myosin genes in vertebrate cell types (Proceedings of the National Academy of Sciences of the United States of America (July 5, 1994) 91 (6549-6553)) (1994) (3)
- Myosin superfamily: a multitude of myosins. (1993) (3)
- Plus‐end directed myosins accelerate actin filament sliding by single‐headed myosin VI (2012) (2)
- Enterocyte Cytoskeleton: Its Structure and Function (2011) (1)
- Membrane-cytoskeleton mechanical feedback mediated by myosin-I controls phagocytic efficiency (2018) (1)
- Effect of Probiotic and Pathogenic Bacteria on Drosophila Intestinal Pathology (2014) (1)
- Studies on the mechanochemical properties of brain myosin-V (1998) (0)
- High affinity binding of brain myosin-V to actin in the presence of 'Ca POT. 2+' and ATP (1998) (0)
- Actin in the Brush-Border of Epithelial C (electron microscopy/gel electrophoresis/G to F transfoi (2016) (0)
- Role of Myosin in Terminal Web Contraction Intestinal Epithelial Brush Borders in Isolated (2002) (0)
- Isolation of Chicken Brush Borders and TW 260 / 240 : Brush borders were isolated from the small intestines of chickens by the method of Mooseker and Howe (2002) (0)
- Structural and functional analysis of the 110 kD protein (BBMI) from the brush border enterocytes (1990) (0)
- Sperm Assembles on Only One Actin Filament: A Behavior Regulated by Profilin End of an (2002) (0)
- MARY itro motility of immunoadsorbed brain m somal process and optical tweezer-bas ph (0)
- Editorial Board (2013) (0)
- Title Myosin-1 a is critical for normal brush border structure andcomposition (2008) (0)
- Molecular analysis of the tight junction (1989) (0)
- Brush Border Cytoskeletonand Integrationof CellularFunctions (1984) (0)
- Editorial Board (2008) (0)
- differentiationfor specific signaling pathways during intestinal Gene expression profiling of Caco-2 BBe cells suggests a (2015) (0)
- on Spectrin-Actin Interactions (1987) (0)
- Cell motility. Myosin linkage strengthened. (1989) (0)
- Editorial Board (1981) (0)
- Membrane-cytoskeletal crosstalk mediated by myosin-I regulates adhesion turnover during phagocytosis (2019) (0)
- pathway in adult and developing proximal tubules Expression of myosin VI within the early endocytic (2016) (0)
- Calcium-dependent regulation of cytoskeletal structure and contractility in the intestinal brush border. (1984) (0)
- A multitude of myosins As more and more myosins are being discovered they are seen to fall into distinct classes of ancient lineage, but their functions are only just beginning to be elucidated. (1993) (0)
- Chicken brain p190: a member of a new class of unconventional myosin that includes to mouse homolog, iolute , and the niyo2 gene product (1991) (0)
- Role of Myosin1a in regulated exocytosis of CFTR in villus enterocytes (2013) (0)
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