Magdy K. Younes
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Magdy K. Younesengineering Degrees
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Biomedical Engineering
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Magdy K. Younesphilosophy Degrees
Philosophy
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Engineering Philosophy
Magdy K. Younes's Degrees
- PhD Biomedical Engineering University of California, Berkeley
- Doctorate Medicine University of California, San Francisco
Why Is Magdy K. Younes Influential?
(Suggest an Edit or Addition)Magdy K. Younes's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Proportional assist ventilation, a new approach to ventilatory support. Theory. (1992) (452)
- Chemical control stability in patients with obstructive sleep apnea. (2001) (405)
- Role of arousals in the pathogenesis of obstructive sleep apnea. (2004) (371)
- Contributions of upper airway mechanics and control mechanisms to severity of obstructive apnea. (2003) (246)
- Proportional assist ventilation. Results of an initial clinical trial. (1992) (239)
- Arousal from sleep: implications for obstructive sleep apnea pathogenesis and treatment. (2014) (219)
- Role of respiratory control mechanisms in the pathogenesis of obstructive sleep disorders. (2008) (209)
- Control of tidal volume and respiratory frequency in anesthetized cats. (1973) (191)
- Response of ventilator-dependent patients to different levels of pressure support and proportional assist. (1999) (182)
- Mechanisms of breathing instability in patients with obstructive sleep apnea. (2007) (161)
- Respiratory mechanics and breathing pattern during and following maximal exercise. (1984) (157)
- Susceptibility to periodic breathing with assisted ventilation during sleep in normal subjects. (1998) (146)
- Sleep monitoring in the intensive care unit: comparison of nurse assessment, actigraphy and polysomnography (2008) (144)
- Effect of dynamic airway compression on breathing pattern and respiratory sensation in severe chronic obstructive pulmonary disease. (2015) (132)
- Noninvasive positive-pressure ventilation in acute respiratory distress without prior chronic respiratory failure. (1996) (128)
- Improvement in exercise endurance in patients with chronic airflow limitation using continuous positive airway pressure. (1988) (127)
- Determinants of ventilatory instability in obstructive sleep apnea: inherent or acquired? (2009) (125)
- Proportional Assist Ventilation (2003) (124)
- Performance of an automated polysomnography scoring system versus computer-assisted manual scoring. (2013) (123)
- A method for measuring passive elastance during proportional assist ventilation. (2001) (122)
- Effect of continuous positive airway pressure on respiratory sensation in patients with chronic obstructive pulmonary disease during submaximal exercise. (1988) (113)
- A method for noninvasive determination of inspiratory resistance during proportional assist ventilation. (2001) (110)
- Relationship between arousal intensity and heart rate response to arousal. (2014) (107)
- Effect of inspiratory muscle fatigue on breathing pattern. (1985) (98)
- Odds ratio product of sleep EEG as a continuous measure of sleep state. (2015) (94)
- Effect of pressure assist on ventilation and respiratory mechanics in heavy exercise. (1989) (87)
- Breathing pattern during maximal exercise and during submaximal exercise with hypercapnia. (1987) (82)
- A model for the relation between respiratory neural and mechanical outputs. I. Theory. (1981) (82)
- Response of ventilator-dependent patients to delayed opening of exhalation valve. (2002) (80)
- A method for monitoring and improving patient: ventilator interaction (2007) (75)
- Longitudinal distribution of pulmonary vascular resistance with very high pulmonary blood flow. (1987) (73)
- Response of ventilator-dependent patients to different levels of proportional assist. (1996) (73)
- Genioglossus activity available via non-arousal mechanisms vs. that required for opening the airway in obstructive apnea patients. (2012) (71)
- Staging Sleep in Polysomnograms: Analysis of Inter-Scorer Variability. (2016) (69)
- Arousal Intensity is a Distinct Pathophysiological Trait in Obstructive Sleep Apnea. (2016) (68)
- Agreement in computer-assisted manual scoring of polysomnograms across sleep centers. (2013) (68)
- Effect of ventilator flow rate on respiratory timing in normal humans. (1999) (67)
- Interaction between chemical factors and duration of apnea following lung inflation. (1974) (66)
- Hypoxic exposure and activation of the afterdischarge mechanism in conscious humans. (1990) (66)
- Effect of inspiratory flow rate on respiratory rate in intubated ventilated patients. (1997) (64)
- Determinants of thoracic excursions during exercise (1991) (64)
- Characteristics of inspiratory inhibition by phasic volume feedback in cats. (1978) (63)
- Control of breathing during sleep assessed by proportional assist ventilation. (1998) (62)
- Effect of tidal volume and PEEP on rate of edema formation in in situ perfused canine lobes. (1988) (60)
- Response of genioglossus muscle to increasing chemical drive in sleeping obstructive apnea patients. (2011) (59)
- Effect of inspiratory flow rate on respiratory output in normal subjects. (1992) (56)
- Phasic vagal influence on inspiratory motor output in anesthetized human subjects. (1980) (55)
- Effects of inspiratory muscle unloading on the response of respiratory motor output to CO2. (1997) (54)
- Obstructive sleep apnea. (2012) (54)
- Load responses, dyspnea, and respiratory failure. (1990) (51)
- Patient-ventilator interaction with pressure-assisted modalities of ventilatory support (1993) (49)
- Breathing pattern during and after maximal exercise in patients with chronic obstructive lung disease, interstitial lung disease, and cardiac disease, and in normal subjects. (2015) (48)
- Pentobarbital sedation increases genioglossus respiratory activity in sleeping rats. (2007) (46)
- The Sleep Apnea-specific Pulse Rate Response Predicts Cardiovascular Morbidity and Mortality. (2021) (45)
- Silent hypoxaemia in COVID‐19 patients (2020) (44)
- A model for the relation between respiratory neural and mechanical outputs. III. Validation. (1981) (44)
- Steady-state response of normal subjects to inspiratory resistive load. (1986) (43)
- Hypoxic respiratory response during acute stable hypocapnia. (2003) (43)
- Performance of a New Portable Wireless Sleep Monitor. (2017) (43)
- An apparatus for altering the mechanical load of the respiratory system. (1987) (42)
- Immediate postarousal sleep dynamics: an important determinant of sleep stability in obstructive sleep apnea. (2016) (39)
- The case for using digital EEG analysis in clinical sleep medicine (2017) (38)
- Mechanisms of respiratory load compensation (1995) (38)
- Sleep and Pathological Wakefulness at the Time of Liberation from Mechanical Ventilation (SLEEWE). A Prospective Multicenter Physiological Study (2019) (37)
- Respiratory response to CO2 during pressure-support ventilation in conscious normal humans. (1997) (37)
- Model based analysis of sleep disordered breathing in congestive heart failure (2007) (37)
- Systemic vs. central administration of common hypnotics reveals opposing effects on genioglossus muscle activity in rats. (2008) (36)
- Role of central respiratory muscle fatigue in endurance exercise in normal subjects. (1994) (35)
- Effect of five human anesthetics on respiratory control in cats. (1978) (33)
- A model for the relation between respiratory neural and mechanical outputs. II. Methods. (1981) (33)
- Expiratory resistive loading in patients with severe chronic air-flow limitation. An evaluation of ventilatory mechanics and compensatory responses. (1987) (33)
- Arousal Responses during Overnight Polysomnography and their Reproducibility in Healthy Young Adults. (2015) (32)
- Ventilatory stability during sleep studied with proportional assist ventilation (PAV). (1996) (32)
- Effects of breathing route, temperature and volume of inspired gas, and airway anesthesia on the response of respiratory output to varying inspiratory flow. (1996) (31)
- A method for the assessment of phasic vagal influence on tidal volume. (1975) (31)
- Lack of radiographic evidence of interstitial pulmonary edema after maximal exercise in normal subjects. (1988) (30)
- Effect of alveolar hypoxia on pulmonary fluid filtration in in situ dog lungs. (1988) (30)
- Central adaptation to inspiratory-inhibiting expiratory-prolonging vagal input. (1985) (30)
- Response of normal subjects to inspiratory resistive unloading. (1989) (30)
- Reliability of the American Academy of Sleep Medicine Rules for Assessing Sleep Depth in Clinical Practice. (2018) (28)
- Accuracy of Automatic Polysomnography Scoring Using Frontal Electrodes. (2016) (28)
- Proportional Assist Ventilation and Pressure Support Ventilation: Similarities and Differences (1991) (28)
- Contribution of arousal from sleep to postevent tachycardia in patients with obstructive sleep apnea. (2013) (28)
- Breathing pattern during and after exercise of different intensities. (1985) (27)
- Utility of Technologist Editing of Polysomnography Scoring Performed by a Validated Automatic System. (2015) (27)
- Effects of non-REM sleep on the response of respiratory output to varying inspiratory flow. (1996) (26)
- CrossTalk proposal: Elevated loop gain is a consequence of obstructive sleep apnoea (2014) (26)
- Abnormal Sleep, Circadian Rhythm Disruption, and Delirium in the ICU: Are They Related? (2020) (25)
- External mechanical loading in conscious humans: role of upper airway mechanoreceptors. (1988) (25)
- Effects of expiratory resistive load on respiratory motor output in conscious humans. (1987) (25)
- Respiratory response to CO2 in the hypocapnic range in awake humans. (1995) (25)
- Relation between respiratory neural output and tidal volume. (1984) (24)
- Apnea following mechanical ventilation may not be caused by neuromechanical influences. (2001) (23)
- Distensibility and pressure-flow relationship of the pulmonary circulation. I. Single-vessel model. (1990) (22)
- Association of novel measures of sleep disturbances with blood pressure: the Multi-Ethnic Study of Atherosclerosis (2019) (22)
- Respiratory control during volume-cycled ventilation in normal humans. (1996) (22)
- Temporal changes in effectiveness of an inspiratory inhibitory electrical pontine stimulus. (1987) (22)
- Mechanism of rapid ventilatory compensation to added elastic loads in cats. (1973) (20)
- Exercise- and cold-induced asthma. (1995) (20)
- Distensibility and pressure-flow relationship of the pulmonary circulation. II. Multibranched model. (1990) (20)
- Effects of inspiratory flow on diaphragmatic motor output in normal subjects. (2000) (20)
- Mechanism of detection of resistive loads in conscious humans. (1992) (20)
- Effect of breathing pattern and level of ventilation on pulmonary fluid filtration in dog lung. (1992) (19)
- Graphical Analysis of Patient Performance in the Pulmonary Function Laboratory. (1980) (19)
- Heritability of Heart Rate Response to Arousals in Twins (2017) (19)
- Driving pressure during assisted mechanical ventilation Is it controlled by patient brain? (2016) (18)
- An approach to the study of upper airway function in humans. (1994) (18)
- Effect of slowly increasing elastic load on breathing in conscious humans. (1991) (17)
- Role of the chest wall in detection of added elastic loads. (1990) (17)
- Graded inspiratory inhibition: specific effects of flow rate. (1979) (16)
- Comparing two measures of sleep depth/intensity. (2020) (15)
- Powerful respiratory stimulation by thin muscle afferents. (1999) (15)
- CONTROL OF BREATHING RELEVANT TO MECHANICAL VENTILATION (1998) (15)
- Minimizing Interrater Variability in Staging Sleep by Use of Computer-Derived Features. (2016) (15)
- Short-term potentiation in the control of pharyngeal muscles in obstructive apnea patients. (2014) (14)
- Medullary metastasis causing impairment of respiratory pressure output with intact respiratory rhythm. (1999) (14)
- Assessment of intervention-related changes in non-rapid-eye-movement sleep depth: importance of sleep depth changes within stage 2. (2017) (14)
- Temporal changes in effectiveness of a constant inspiratory-terminating vagal stimulus. (1981) (13)
- Arterial occlusion versus isofiltration pulmonary capillary pressures during very high flow. (1987) (12)
- Relation between respiratory valve dead space and tidal volume. (1980) (11)
- Pathogenesis of Obstructive Sleep Apnea. (2019) (10)
- Dynamic Intrinsic PEEP (PEEPi,dyn) (2000) (10)
- Interhemispheric sleep depth coherence predicts driving safety in sleep apnea (2020) (10)
- Enhancements to the multiple sleep latency test (2016) (10)
- Steady-state response of quadriplegic subjects to inspiratory resistive load. (1986) (9)
- Mechanism of Excessive Wake Time When Associated with Obstructive Apnea and/or Periodic Limb Movements. (2020) (9)
- Why does airway pressure rise sometimes near the end of inflation during pressure support? (2007) (9)
- Spindles are highly heritable as identified by different spindle detectors. (2020) (9)
- Steady-state ventilatory responses to expiratory resistive loading in quadriplegics. (1993) (8)
- Termination of inspiration through graded inhibition of inspiratory activity. (1978) (8)
- Measurement of the CO2 apneic threshold. (2003) (7)
- Effects of pulmonary and intercostal denervation on the response of breathing frequency to varying inspiratory flow. (1998) (7)
- Short-term effect of tidal pleural pressure swings on pulmonary blood flow during rest and exercise. (1991) (7)
- 0211 Odds Ratio Product: A Measure of Sleep Homeostasis Following Prolonged Wakefulness (2018) (7)
- Characteristics and Reproducibility of Novel Sleep EEG Biomarkers and their Variation with Sleep Apnea and Insomnia in a Large Community-Based Cohort. (2021) (7)
- Association of sleep spindle characteristics with executive functioning in healthy sedentary middle-aged and older adults (2019) (7)
- Control of Breathing During Mechanical Ventilation (2005) (7)
- Fifty Years of Physiology in Obstructive Sleep Apnea. (2017) (6)
- Respiratory response to pulmonary vascular congestion in intact conscious dogs. (1993) (6)
- Results of an Initial Clinical Trial1-4 (1992) (6)
- Closing volume after inspiratory resistive loading to fatigue. (1987) (5)
- Dynamic intrinsic PEEP (PEEP(i),dyn): is it worth saving? (2000) (5)
- Association of sleep spindle characteristics with executive functioning in healthy sedentary middle‐aged and older adults (2020) (5)
- Traffic noise and its impact on sleep depth measured by the odds ratio product (2019) (5)
- Maturational trajectories of non-rapid eye movement slow wave activity and odds ratio product in a population-based sample of youth. (2021) (5)
- Sex and Pubertal Differences in the Maturational Trajectories of Sleep Spindles in the Transition from Childhood to Adolescence: A Population-Based Study (2021) (5)
- Short Term Potentiation (STP) Of Genioglossus Activity In Patients With Obstructive Apnea (OSA) (2011) (5)
- 1013 Novel Quantitative EEG Exposures and Risk of Incident MCI and Dementia in Older Women (2018) (5)
- Steady-state response of normal subjects to an inspiratory sinusoidal pressure load. (1988) (4)
- Data on respiratory variables in critically ill patients with acute respiratory failure placed on proportional assist ventilation with load adjustable gain factors (PAV+) (2016) (4)
- Ventilatory effect of acute pulmonary hypothermia. (1990) (4)
- Performance Of An Automated Polysomnography Scoring System Vs. Computer-Assisted Manual Scoring (2012) (4)
- Hypoxic exposure and activation of the after-discharge mechanism. (1990) (4)
- Exercise endurance and arterial desaturation in normobaric hypoxia with increased chemosensitivity. (1991) (4)
- Traffic noise-induced changes in wake-propensity measured with the Odds-Ratio Product (ORP) (2021) (4)
- Sleep architecture based on sleep depth and propensity: patterns in different demographics and sleep disorders and association with health outcomes (2022) (3)
- Relation between arousability and outcome of upper airway stimulation in the Stimulation for Apnea Reduction (STAR) Trial. (2020) (3)
- A novel EEG marker predicts perceived SLEEPINESS AND poor sleep quality. (2022) (3)
- To sleep: perchance to ditch the ventilator (2018) (3)
- Termination of inspiration through graded inhibition of inspiratory activity. (1978) (3)
- Effect of phase shifts in pressure-flow relationship on response to inspiratory resistance. (1989) (3)
- 0314 Changes in Sleep Depth following Sleep Deprivation Assessed by Three Methods (2019) (3)
- Pharyngeal anatomy and severity of obstructive apnea. (2004) (3)
- Proportional Assist Ventilation: Technique and Implementation (1999) (3)
- Adherence Index: sleep depth and nocturnal hypoventilation predict long-term adherence with positive airway pressure therapy in severe obstructive sleep apnea. (2022) (2)
- 0148 Assessment of Sleep Depth and Propensity during Sleep Restriction using the Odds-Ratio-Product (2018) (2)
- 0282 Correlation Between Sleep Depth in the Right and Left Cerebral Hemispheres Following Sleep Deprivation, Restriction or Noise Exposure (2020) (2)
- 0961 Range And Reproducibility Of EEG Biomarkers For Cognition Across Five Years. (2019) (2)
- Effects of Sedatives on Sleep Architecture Measured With Odds Ratio Product in Critically Ill Patients (2021) (2)
- 0748 Relationship Between Neurobehavioral Function And Sleep Depth In Children With Obstructive Sleep Apnea (2018) (2)
- Sleep Propensity and Sleep Apnea-Specific Hypoxia Are Associated with Excessive Daytime Sleepiness (2020) (2)
- Impact of intermittent hypoxia on human vascular responses during sleep (2021) (2)
- What short‐term potentiation is and why it may be relevant to obstructive sleep apnoea (2018) (2)
- 0131 Planes, Trains And Automobiles: Traffic Noise And Its Impact On Sleep Depth Measured By Odds Ratio Product (2019) (1)
- Mechanism of detection of added respiratory loads. (1990) (1)
- Mechanism of excessive wake time when associated with obstructive sleep apnea and/or movement disorders (2019) (1)
- 0049 Odds Ratio Product as a Measure of Sleep Depth During REM Sleep: Effects on REM Duration and REM Sleep Fragmentation (2020) (1)
- Association of a Novel EEG Metric of Sleep Depth/Intensity with Attention-Deficit/Hyperactivity, Learning and Internalizing Disorders and their Pharmacotherapy in Adolescence. (2021) (1)
- 0254 Association of Slow Wave Activity and Odds Ratio Product with Internalizing and Externalizing Problems in Children and Adolescents (2022) (1)
- 0009 A Comparison of the Effects of Gaboxadol and Sleep Restriction on Sleep Depth Assessed by the Odds-Ratio-Product (2018) (1)
- Contribution of airway closure to pulmonary shunting in hypoxemic surgical patients. (1975) (1)
- 0091 Spindle Characteristics Are Associated With Executive Function In Healthy Older Adults From The Brain In Motion Study (2019) (1)
- Con: Can Physiological Risk Factors for Obstructive Sleep Apnea be Determined by Analysis of Data Obtained from Routine Polysomnography? (2023) (1)
- Agreement In Scoring Polysomnograms Within And Across Sleep Centers (2012) (1)
- The Sleep Homeostatic Response to Sleep Deprivation in Humans is Heritable. (2022) (1)
- apnea pathogenesis and treatment Arousal from sleep: implications for obstructive sleep (2015) (1)
- 0280 Change in Sleep Depth Across the Night as a Measure of Sleep Adequacy (2020) (1)
- sleep in obstructive sleep apnea hypopnea syndrome lining liquid and upper airway collapsibility during Relationship between surface tension of upper airway (2015) (1)
- Reply to Schwarz et al.: Pathological Sleep and Wakefulness in the ICU and Weaning Failure: A Causal Relationship? (2019) (0)
- Cross-sectional association of traditional and novel polysomnography metrics with atherosclerosis in obstructive sleep apnoea (2019) (0)
- Genioglossus (GG) Responses to Increasing Chemical Drive in Obstructive Apnea (OSA) Patients during Sleep. (2009) (0)
- 0536 Association of a Novel EEG Biomarker of Sleep Depth with Sleep Disordered Breathing in Adolescents (2022) (0)
- under controlled ventilation conditions Cardiac and respiratory activity at arousal from sleep (2013) (0)
- Table 1 — Agreement Between Polysomnography Variables When Scored Manually and Automatically by Central or Frontal EEG Signals (2016) (0)
- Contribution of Obstructive Sleep Apnea to Disrupted Sleep in a Large Clinical Cohort of Patients with Suspected OSA. (2023) (0)
- Rebuttal from Magdy Younes (2014) (0)
- 5phenotype linked to mouse chromosome Hypercapnic duty cycle is an intermediate (2015) (0)
- 0426 Shallower sleep depth in the laboratory is not related to insomnia severity (2022) (0)
- 0327 Relation between Speed of Wake-Sleep Transitions and Wake Time in Polysomnograms. (2019) (0)
- Proportional assist ventilation using a disturbance observer and predictive control (2006) (0)
- 0691 Comparison Of Odds Ratio Product And Other Polysomnographic Metrics Among Responders And Non-responders To Upper Airway Stimulation Treatment Of Obstructive Sleep Apnea (2020) (0)
- Mechanism of excessive wake time when associated with obstructive sleep apnea or periodic limb movements (2020) (0)
- Low-frequency precursors of sleep spindles in EEG in a rat model of absence epilepsy (2018) (0)
- 628 Longitudinal Association between NREM Sleep Depth and Arousability with ADHD and Internalizing Disorders in Adolescence (2021) (0)
- Association of Novel Measures of Sleep Disturbances and Blood Pressure: The MESA Study (2019) (0)
- duration through the night in obstructive sleep apnea Effect of topical upper airway anesthesia on apnea (2015) (0)
- 0606 A Paradigm for Testing the Accuracy of Digital Sleep Staging Systems (2022) (0)
- output in normal subjects Effects of inspiratory flow on diaphragmatic motor (2015) (0)
- Airway Occlusion Pressure Revisited (2020) (0)
- Post-Event Tachycardia Combined with Sleep Apnea-Specific Hypoxic Burden Is a Strong Predictor of Cardiovascular Morbidity and Mortality (2020) (0)
- Ventilatory effects of high and pulsatile blood flow in the pulmonary circulation. (1990) (0)
- GENIOGLOSSUS RESPIRATORY ACTIVITY IN SLEEP (2007) (0)
- The Control of Breathing During Mechanical Ventilation. (2019) (0)
- How Much Genioglossus Activation Is Required During Sleep To Open The Airway Of Patients With Obstructive Sleep Apnea (2011) (0)
- pressure during wakefulness and sleep in healthy men responses to brief pulses of negative upper-airway Effects of hypoxia on genioglossus and scalene reflex (2015) (0)
- 151 Sex Differences in the Maturational Trajectories of Sleep Spindles in the Transition from Childhood to Adolescence (2021) (0)
- proportional assist ventilation Control of breathing during sleep assessed by (2015) (0)
- Upper Airway Control and Function : Implications for Sleep-Disordered Breathing Arousal from sleep : implications for obstructive sleep apnea pathogenesis and treatment (2014) (0)
- A novel EEG marker predicts perceived sleepiness and poor sleep quality. (2022) (0)
- 0190 Association of Sleep Spindle Activity with Cognition in Youth from the General Population (2022) (0)
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