Makoto Mark Taketo
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Computer Science
Makoto Mark Taketo's Degrees
- PhD Computer Science University of Tokyo
- Masters Computer Science Kyoto University
- Bachelors Computer Science Kyoto University
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(Suggest an Edit or Addition)Makoto Mark Taketo's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Suppression of Intestinal Polyposis in Apc Δ716 Knockout Mice by Inhibition of Cyclooxygenase 2 (COX-2) (1996) (2550)
- Intestinal polyposis in mice with a dominant stable mutation of the β‐catenin gene (1999) (1205)
- Canonical Wnt/beta-catenin signaling prevents osteoblasts from differentiating into chondrocytes. (2005) (1085)
- Intestinal Tumorigenesis Initiated by Dedifferentiation and Acquisition of Stem-Cell-like Properties (2013) (928)
- Cyclooxygenase-2 inhibitors in tumorigenesis (Part II). (1998) (759)
- TGF-beta receptor type II deficiency results in defects of yolk sac hematopoiesis and vasculogenesis. (1996) (704)
- Nonmyelinating Schwann Cells Maintain Hematopoietic Stem Cell Hibernation in the Bone Marrow Niche (2011) (695)
- Interactions between Sox9 and β-catenin control chondrocyte differentiation (2004) (656)
- Intestinal Tumorigenesis in Compound Mutant Mice of both Dpc4(Smad4) and Apc Genes (1998) (631)
- Wnt signalling induces maturation of Paneth cells in intestinal crypts (2005) (622)
- Wnt/β-catenin signaling controls development of the blood–brain barrier (2008) (606)
- Loss of Apc heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated Apc gene. (1995) (605)
- Subtypes of medulloblastoma have distinct developmental origins (2010) (581)
- FVB/N: an inbred mouse strain preferable for transgenic analyses. (1991) (581)
- Hemoprotein Bach1 regulates enhancer availability of heme oxygenase‐1 gene (2002) (575)
- Acceleration of intestinal polyposis through prostaglandin receptor EP2 in ApcΔ716 knockout mice (2001) (567)
- Early embryonic lethality caused by targeted disruption of the mouse thioredoxin gene. (1996) (549)
- beta-Catenin signals regulate cell growth and the balance between progenitor cell expansion and differentiation in the nervous system. (2003) (515)
- HDAC1 and HDAC2 Regulate Oligodendrocyte Differentiation By Disrupting β-Catenin-TCF Interaction (2009) (510)
- Berberine and Its More Biologically Available Derivative, Dihydroberberine, Inhibit Mitochondrial Respiratory Complex I (2008) (472)
- Multiple functional defects in peripheral autonomic organs in mice lacking muscarinic acetylcholine receptor gene for the M3 subtype. (2000) (460)
- Adenomatous polyposis coli (APC): a multi-functional tumor suppressor gene (2007) (459)
- Instructive Role of Wnt/ß-Catenin in Sensory Fate Specification in Neural Crest Stem Cells (2004) (429)
- Interactions between Sox9 and beta-catenin control chondrocyte differentiation. (2004) (424)
- Activation of beta-catenin signaling by Rspo1 controls differentiation of the mammalian ovary. (2008) (411)
- Cyclooxygenase-2 inhibitors in tumorigenesis (part I). (1998) (377)
- Continuous tooth generation in mouse is induced by activated epithelial Wnt/β-catenin signaling (2006) (376)
- Chemoprevention of intestinal polyposis in the APCΔ716 mouse by rofecoxib, a specific cyclooxygenase-2 inhibitor (2000) (369)
- Beta-catenin activation is necessary and sufficient to specify the dorsal dermal fate in the mouse. (2006) (365)
- Apc modulates embryonic stem-cell differentiation by controlling the dosage of β-catenin signaling (2002) (362)
- Mesp2: a novel mouse gene expressed in the presegmented mesoderm and essential for segmentation initiation. (1997) (342)
- The renewal and differentiation of Isl1+ cardiovascular progenitors are controlled by a Wnt/beta-catenin pathway. (2007) (339)
- β-catenin signaling controls metastasis in Braf-activated Pten-deficient melanomas. (2011) (324)
- Wnt/β-catenin signaling directs multiple stages of tooth morphogenesis (2008) (321)
- Homozygous Inactivation of Sox9 Causes Complete XY Sex Reversal in Mice1 (2006) (318)
- Stabilization of beta-catenin in XY gonads causes male-to-female sex-reversal. (2008) (317)
- Early embryonic lethality caused by targeted disruption of the mouse selenocysteine tRNA gene (Trsp). (1997) (310)
- ROCK-I regulates closure of the eyelids and ventral body wall by inducing assembly of actomyosin bundles (2005) (303)
- Wnt signaling regulates pancreatic β cell proliferation (2007) (298)
- Activated macrophages promote Wnt signalling through tumour necrosis factor-α in gastric tumour cells (2008) (298)
- Canonical Wnt signaling is a positive regulator of mammalian cardiac progenitors (2007) (295)
- Dclk1 distinguishes between tumor and normal stem cells in the intestine (2012) (293)
- A β-catenin gradient links the clock and wavefront systems in mouse embryo segmentation (2008) (292)
- Formation of multiple hearts in mice following deletion of beta-catenin in the embryonic endoderm. (2002) (285)
- Wnt/beta-catenin signaling promotes expansion of Isl-1-positive cardiac progenitor cells through regulation of FGF signaling. (2007) (281)
- The Wnt/beta-catenin pathway modulates vascular remodeling and specification by upregulating Dll4/Notch signaling. (2010) (276)
- Homeodomain-Mediated β-Catenin-Dependent Switching Events Dictate Cell-Lineage Determination (2006) (267)
- Size- and invasion-dependent increase in cyclooxygenase 2 levels in human colorectal carcinomas. (1998) (266)
- SMAD4-deficient intestinal tumors recruit CCR1+ myeloid cells that promote invasion (2007) (265)
- Coordinated Activation of Wnt in Epithelial and Melanocyte Stem Cells Initiates Pigmented Hair Regeneration (2011) (263)
- Gut Microbiota Promotes Obesity-Associated Liver Cancer through PGE2-Mediated Suppression of Antitumor Immunity. (2017) (262)
- Pivotal Role of CXCR3 in Melanoma Cell Metastasis to Lymph Nodes (2004) (262)
- Targeted Disruption of the Mouse Rho-Associated Kinase 2 Gene Results in Intrauterine Growth Retardation and Fetal Death (2003) (259)
- Two distinct classes of muscarinic action on hippocampal inhibitory synapses: M2‐mediated direct suppression and M1/M3‐mediated indirect suppression through endocannabinoid signalling (2004) (254)
- Cyclooxygenase 2- and prostaglandin E2 receptor EP2-dependent angiogenesis in ApcΔ716 mouse intestinal polyps (2002) (252)
- Hyperplastic gastric tumors induced by activated macrophages in COX‐2/mPGES‐1 transgenic mice (2004) (247)
- Wnt signaling induces proliferation of sensory precursors in the postnatal mouse cochlea (2012) (245)
- Increased Wingless (Wnt) signaling in pituitary progenitor/stem cells gives rise to pituitary tumors in mice and humans (2011) (244)
- MesP1: a novel basic helix-loop-helix protein expressed in the nascent mesodermal cells during mouse gastrulation. (1996) (241)
- Mouse models of colon cancer. (2009) (240)
- Wnt signals mediate a fate decision between otic placode and epidermis (2006) (238)
- Canonical WNT signaling components in vascular development and barrier formation. (2014) (234)
- Modulation of Synaptic Plasticity by Physiological Activation of M1 Muscarinic Acetylcholine Receptors in the Mouse Hippocampus (2005) (232)
- Effects of canonical Wnt signaling on dorso-ventral specification of the mouse telencephalon. (2005) (229)
- Wnt antagonism of Shh facilitates midbrain floor plate neurogenesis (2009) (228)
- Hematopoietic stem cell and multilineage defects generated by constitutive beta-catenin activation. (2006) (227)
- Mice Lacking M2 and M3 Muscarinic Acetylcholine Receptors Are Devoid of Cholinergic Smooth Muscle Contractions But Still Viable (2002) (225)
- Global metabolic reprogramming of colorectal cancer occurs at adenoma stage and is induced by MYC (2017) (225)
- Hematopoietic stem cell and multilineage defects generated by constitutive β-catenin activation (2006) (224)
- Colonic polyposis caused by mTOR-mediated chromosomal instability in Apc+/Δ716 Cdx2+/− compound mutant mice (2003) (222)
- Tertiary hypothyroidism and hyperglycemia in mice with targeted disruption of the thyrotropin-releasing hormone gene. (1997) (213)
- Osteocytes mediate the anabolic actions of canonical Wnt/β-catenin signaling in bone (2015) (212)
- Wnt/beta-catenin signaling directs multiple stages of tooth morphogenesis. (2008) (210)
- Gastric and duodenal polyps in Smad4 (Dpc4) knockout mice. (1999) (209)
- Wnt signaling regulates pancreatic beta cell proliferation. (2007) (207)
- Stabilization of β-catenin impacts pancreas growth (2006) (205)
- Suppression of colon cancer metastasis by Aes through inhibition of Notch signaling. (2011) (200)
- Carcinogenesis in mouse stomach by simultaneous activation of the Wnt signaling and prostaglandin E2 pathway. (2006) (200)
- Wnt activation in nail epithelium couples nail growth to digit regeneration (2013) (199)
- Wnt3a/β-catenin signaling controls posterior body development by coordinating mesoderm formation and segmentation (2007) (197)
- Somatic activation of β-catenin bypasses pre-TCR signaling and TCR selection in thymocyte development (2001) (196)
- Distinct roles of Wnt/β-catenin and Bmp signaling during early cardiogenesis (2007) (195)
- β-Catenin regulates Cripto- and Wnt3-dependent gene expression programs in mouse axis and mesoderm formation (2003) (193)
- Stromal Fibroblasts Activated by Tumor Cells Promote Angiogenesis in Mouse Gastric Cancer* (2008) (186)
- β-catenin is a central mediator of pro-fibrotic Wnt signaling in systemic sclerosis (2012) (184)
- Prospero-related homeobox 1 gene (Prox1) is regulated by canonical Wnt signaling and has a stage-specific role in adult hippocampal neurogenesis (2011) (180)
- Activation of β-catenin signaling programs embryonic epidermis to hair follicle fate (2008) (179)
- β-catenin mediates glandular formation and dysregulation of β-catenin induces hyperplasia formation in the murine uterus (2009) (177)
- Postsynaptic M1 and M3 receptors are responsible for the muscarinic enhancement of retrograde endocannabinoid signalling in the hippocampus (2003) (175)
- Stabilization of β-catenin in the mouse zygote leads to premature epithelial-mesenchymal transition in the epiblast (2004) (171)
- Wnt/β-Catenin Pathway in Podocytes Integrates Cell Adhesion, Differentiation, and Survival* (2011) (171)
- Cyclooxygenase 2- and prostaglandin E(2) receptor EP(2)-dependent angiogenesis in Apc(Delta716) mouse intestinal polyps. (2002) (170)
- Morphological and Molecular Processes of Polyp Formation in ApcΔ716 Knockout Mice (1997) (166)
- Lack of tumorigenesis in the mouse liver after adenovirus-mediated expression of a dominant stable mutant of beta-catenin. (2002) (165)
- Beta-catenin regulates differentiation of respiratory epithelial cells in vivo. (2005) (164)
- Wt1 negatively regulates β-catenin signaling during testis development (2008) (163)
- M3 muscarinic acetylcholine receptor plays a critical role in parasympathetic control of salivation in mice (2004) (161)
- Targeted deletion of keratins 18 and 19 leads to trophoblast fragility and early embryonic lethality (2000) (160)
- Mucosal prolapse in the pathogenesis of Peutz-Jeghers polyposis (2005) (156)
- Hepatocarcinogenesis in Mice with β-Catenin and Ha-Ras Gene Mutations (2004) (154)
- Genetic interaction between Wnt/beta-catenin and BMP receptor signaling during formation of the AER and the dorsal-ventral axis in the limb. (2003) (153)
- Misregulated Wnt/beta-catenin signaling leads to ovarian granulosa cell tumor development. (2005) (153)
- β-Catenin destruction complex-independent regulation of Hippo–YAP signaling by APC in intestinal tumorigenesis (2015) (153)
- A randomized, double-blind, placebo-controlled trial of the effects of rofecoxib, a selective cyclooxygenase-2 inhibitor, on rectal polyps in familial adenomatous polyposis patients. (2003) (152)
- The duality of beta-catenin function: a requirement in lens morphogenesis and signaling suppression of lens fate in periocular ectoderm. (2005) (152)
- Gastrointestinal hamartomatous polyposis in Lkb1 heterozygous knockout mice. (2002) (151)
- Cranial neural crest cells regulate head muscle patterning and differentiation during vertebrate embryogenesis (2007) (150)
- Stabilization of beta-catenin impacts pancreas growth. (2006) (150)
- Distinct roles of Wnt/beta-catenin and Bmp signaling during early cardiogenesis. (2007) (149)
- Inactivation of chemokine (C-C motif) receptor 1 (CCR1) suppresses colon cancer liver metastasis by blocking accumulation of immature myeloid cells in a mouse model (2010) (148)
- Inhibition of the mTORC1 pathway suppresses intestinal polyp formation and reduces mortality in ApcΔ716 mice (2008) (142)
- Suppression of Intestinal Polyposis inApc Δ 716 Knockout Mice by an Additional Mutation in the Cytosolic Phospholipase A2Gene* (2000) (141)
- Wnt4/β-catenin signaling in medullary kidney myofibroblasts. (2013) (141)
- &bgr;-Catenin Downregulation Is Required for Adaptive Cardiac Remodeling (2007) (138)
- Activation of β-catenin in prostate epithelium induces hyperplasias and squamous transdifferentiation (2003) (137)
- Phospolipase A2 and apoptosis. (2002) (136)
- Wnt-β-catenin signaling initiates taste papilla development (2007) (136)
- Ciliary margin transdifferentiation from neural retina is controlled by canonical Wnt signaling. (2007) (135)
- Significance and mechanism of lymph node metastasis in cancer progression. (2011) (134)
- Hedgehog stimulates hair follicle neogenesis by creating inductive dermis during murine skin wound healing (2018) (134)
- Activation of β-catenin signaling in differentiated mammary secretory cells induces transdifferentiation into epidermis and squamous metaplasias (2002) (132)
- Degeneration of the Amygdala/Piriform Cortex and Enhanced Fear/Anxiety Behaviors in Sodium Pump α2 Subunit (Atp1a2)-Deficient Mice (2003) (132)
- The role of CXCR3 and CXCR4 in colorectal cancer metastasis (2013) (131)
- Wnt/BMP signal integration regulates the balance between proliferation and differentiation of neuroepithelial cells in the dorsal spinal cord. (2007) (130)
- Constitutive Activation of Beta-Catenin in Uterine Stroma and Smooth Muscle Leads to the Development of Mesenchymal Tumors in Mice1 (2009) (130)
- Loss of Fgfr2 leads to partial XY sex reversal. (2008) (128)
- WNT signaling increases proliferation and impairs differentiation of stem cells in the developing cerebellum (2012) (128)
- Spatial and temporal regulation of Wnt/beta-catenin signaling is essential for development of the retinal pigment epithelium. (2009) (125)
- Malfunction of Respiratory-Related Neuronal Activity in Na+, K+-ATPase α2 Subunit-Deficient Mice Is Attributable to Abnormal Cl- Homeostasis in Brainstem Neurons (2004) (125)
- Endothelial Wnt/β-catenin signaling inhibits glioma angiogenesis and normalizes tumor blood vessels by inducing PDGF-B expression (2012) (125)
- Multiple roles of mesenchymal β-catenin during murine limb patterning (2006) (122)
- Cytokeratins 8 and 19 in the Mouse Placental Development (2000) (121)
- Sustained epithelial β-catenin activity induces precocious hair development but disrupts hair follicle down-growth and hair shaft formation (2008) (120)
- Constitutive WNT/Beta-Catenin Signaling in Murine Sertoli Cells Disrupts Their Differentiation and Ability to Support Spermatogenesis1 (2010) (120)
- Pax6 is essential for lens fiber cell differentiation (2009) (120)
- Activation of different Wnt/β-catenin signaling components in mammary epithelium induces transdifferentiation and the formation of pilar tumors (2002) (118)
- AML1-ETO requires enhanced C/D box snoRNA/RNP formation to induce self-renewal and leukaemia (2017) (118)
- Cyclooxygenase-2 expression in fibroblasts and endothelial cells of intestinal polyps. (2002) (116)
- A genetic study of the role of the Wnt/beta-catenin signalling in Paneth cell differentiation. (2008) (113)
- Hepatocarcinogenesis in mice with beta-catenin and Ha-ras gene mutations. (2004) (113)
- Frequent mutations that converge on the NFKBIZ pathway in ulcerative colitis (2019) (112)
- RSPO1/β-Catenin Signaling Pathway Regulates Oogonia Differentiation and Entry into Meiosis in the Mouse Fetal Ovary (2011) (112)
- Persistent expression of stabilized beta-catenin delays maturation of radial glial cells into intermediate progenitors. (2007) (111)
- Temporal control of neural crest lineage generation by Wnt/β-catenin signaling (2012) (110)
- Stabilization of β-catenin induces lesions reminiscent of prostatic intraepithelial neoplasia, but terminal squamous transdifferentiation of other secretory epithelia (2002) (110)
- Phases of canonical Wnt signaling during the development of mouse intestinal epithelium. (2007) (107)
- Constitutive stabilization of ß-catenin in the dental mesenchyme leads to excessive dentin and cementum formation. (2011) (105)
- Cooperation of cyclooxygenase 1 and cyclooxygenase 2 in intestinal polyposis. (2003) (105)
- CDX2 expression in the stomach with intestinal metaplasia and intestinal-type cancer: Prognostic implications. (2002) (105)
- Shutting down Wnt signal–activated cancer (2004) (105)
- Genetic interactions of the androgen and Wnt/beta-catenin pathways for the masculinization of external genitalia. (2009) (104)
- Interactions of Wnt/β-Catenin Signaling and Sonic Hedgehog Regulate the Neurogenesis of Ventral Midbrain Dopamine Neurons (2010) (104)
- Hepatocellular carcinoma caused by loss of heterozygosity in Lkb1 gene knockout mice. (2002) (103)
- β-Catenin Is Required for Prostate Development and Cooperates with Pten Loss to Drive Invasive Carcinoma (2013) (102)
- The Role of Chemokines in Promoting Colorectal Cancer Invasion/Metastasis (2016) (101)
- Dissecting Wnt/β-catenin signaling during gastrulation using RNA interference in mouse embryos (2005) (100)
- Activation of β‐Catenin in mouse prostate causes HGPIN and continuous prostate growth after castration (2009) (99)
- Loss of SMAD4 from colorectal cancer cells promotes CCL15 expression to recruit CCR1+ myeloid cells and facilitate liver metastasis. (2013) (98)
- β-Catenin activation synergizes with PTEN loss to cause bladder cancer formation (2011) (98)
- Temporal control of neural crest lineage generation by Wnt/beta-catenin signaling (2012) (97)
- The M2 Muscarinic Receptor Mediates Contraction through Indirect Mechanisms in Mouse Urinary Bladder (2005) (95)
- Wnt signaling and its downstream target N-myc regulate basal progenitors in the developing neocortex (2010) (95)
- Involvement of Caspase 3 in Apoptotic Death of Cortical Neurons Evoked by DNA Damage (2000) (95)
- COX selectivity and animal models for colon cancer. (2002) (94)
- Dosage-dependent hedgehog signals integrated with Wnt/β-catenin signaling regulate external genitalia formation as an appendicular program (2009) (93)
- β-Catenin Activation Regulates Tissue Growth Non–Cell Autonomously in the Hair Stem Cell Niche (2014) (91)
- Wnt-beta-catenin signaling initiates taste papilla development. (2007) (90)
- Nuclear translocation of beta-catenin in hereditary and carcinogen-induced intestinal adenomas. (1998) (90)
- Multiple roles of mesenchymal beta-catenin during murine limb patterning. (2006) (90)
- Ectodermal Wnt/β-catenin signaling shapes the mouse face. (2011) (89)
- Bmp and Wnt/beta-catenin signals control expression of the transcription factor Olig3 and the specification of spinal cord neurons. (2007) (88)
- Wnt9b-dependent FGF signaling is crucial for outgrowth of the nasal and maxillary processes during upper jaw and lip development (2012) (86)
- Targeted Disruption of Intracellular Type I Platelet Activating Factor-acetylhydrolase Catalytic Subunits Causes Severe Impairment in Spermatogenesis* (2003) (86)
- In Vivo Cochlear Hair Cell Generation and Survival by Coactivation of β-Catenin and Atoh1 (2015) (86)
- Loss of SMAD4 Promotes Colorectal Cancer Progression by Accumulation of Myeloid-Derived Suppressor Cells through the CCL15–CCR1 Chemokine Axis (2015) (86)
- Quantitative analysis of binding parameters of [3H]N-methylscopolamine in central nervous system of muscarinic acetylcholine receptor knockout mice. (2005) (86)
- Mouse models of gastrointestinal tumors (2006) (83)
- Sox9 is required for notochord maintenance in mice. (2006) (83)
- Functional analysis of muscarinic acetylcholine receptors using knockout mice. (2004) (83)
- β-Catenin Activation in Muscle Progenitor Cells Regulates Tissue Repair. (2016) (82)
- Wnt/β-catenin signaling regulates postnatal development and regeneration of the salivary gland. (2010) (82)
- The Wnt/β-Catenin Pathway Interacts Differentially with PTHrP Signaling to Control Chondrocyte Hypertrophy and Final Maturation (2009) (81)
- Increased Relaxant Action of Forskolin and Isoproterenol against Muscarinic Agonist-Induced Contractions in Smooth Muscle from M2 Receptor Knockout Mice (2003) (79)
- Stabilized β-Catenin in Thymic Epithelial Cells Blocks Thymus Development and Function1 (2009) (79)
- COX-2 and colon cancer (1998) (78)
- Morphological and molecular processes of polyp formation in Apc(delta716) knockout mice. (1997) (77)
- Promotion of colorectal cancer invasion and metastasis through activation of NOTCH-DAB1-ABL-RHOGEF protein TRIO. (2015) (77)
- The stabilization of β-catenin leads to impaired primordial germ cell development via aberrant cell cycle progression (2006) (77)
- Ras mutation cooperates with β-catenin activation to drive bladder tumourigenesis (2011) (76)
- Epithelial Wnt/β-catenin signaling regulates palatal shelf fusion through regulation of Tgfβ3 expression. (2011) (75)
- Effects of docosahexaenoic acid (DHA) on intestinal polyp development in ApcΔ716 knockout mice (1995) (74)
- Cystometric findings in mice lacking muscarinic M2 or M3 receptors. (2004) (73)
- Wnt signaling determines ventral spinal cord cell fates in a time-dependent manner (2008) (72)
- Wnt signaling and gastrointestinal tumorigenesis in mouse models (2006) (72)
- Cloning and expression of human B cell-specific transcription factor BACH2 mapped to chromosome 6q15 (2000) (70)
- miR-142-3p balances proliferation and differentiation of mesenchymal cells during lung development (2014) (70)
- Chromosomal instability by β-catenin/TCF transcription in APC or β-catenin mutant cells (2007) (69)
- Hyperplastic gastric tumors with spasmolytic polypeptide-expressing metaplasia caused by tumor necrosis factor-alpha-dependent inflammation in cyclooxygenase-2/microsomal prostaglandin E synthase-1 transgenic mice. (2005) (68)
- Biosynthesis of RNA polymerase in Escherichia coli. IV. Accumulation of intermediates in mutants defective in the subunit assembly. (1977) (67)
- Requirement for tumor suppressor Apc in the morphogenesis of anterior and ventral mouse embryo. (2003) (67)
- Sox9 is required for invagination of the otic placode in mice. (2008) (66)
- Induction and down-regulation of Sox17 and its possible roles during the course of gastrointestinal tumorigenesis. (2009) (66)
- Homologs of Drosophila Fushi-Tarazu factor 1 map to mouse chromosome 2 and human chromosome 9q33. (1995) (66)
- Suppressing TGFβ signaling in regenerating epithelia in an inflammatory microenvironment is sufficient to cause invasive intestinal cancer. (2015) (66)
- KLF5 regulates the integrity and oncogenicity of intestinal stem cells. (2014) (65)
- SHISA6 Confers Resistance to Differentiation-Promoting Wnt/β-Catenin Signaling in Mouse Spermatogenic Stem Cells (2017) (65)
- β‐Catenin activation contributes to the pathogenesis of adenomyosis through epithelial–mesenchymal transition (2013) (64)
- Suppression of intestinal polyp development by low-fat and high-fiber diet in Apc(delta716) knockout mice. (1997) (64)
- Single-Cell Analysis Reveals a Hair Follicle Dermal Niche Molecular Differentiation Trajectory that Begins Prior to Morphogenesis. (2019) (63)
- Two blocks in Moloney murine leukemia virus expression in undifferentiated F9 embryonal carcinoma cells as determined by transient expression assays (1989) (62)
- Suppression of Tubulin Polymerization by the LKB1-Microtubule-associated Protein/Microtubule Affinity-regulating Kinase Signaling* (2007) (60)
- Evidence against dominant negative mechanisms of intestinal polyp formation by Apc gene mutations. (1995) (59)
- Excessive Wnt/β-catenin signaling disturbs tooth-root formation. (2013) (57)
- Phosphorylated β-catenin localizes to centrosomes of neuronal progenitors and is required for cell polarity and neurogenesis in developing midbrain. (2011) (56)
- CCR1-mediated accumulation of myeloid cells in the liver microenvironment promoting mouse colon cancer metastasis (2014) (56)
- β-Catenin activity in the dermal papilla of the hair follicle regulates pigment-type switching (2010) (55)
- SOXC proteins amplify canonical WNT signaling to secure nonchondrocytic fates in skeletogenesis (2014) (55)
- Loss of SMAD4 Promotes Lung Metastasis of Colorectal Cancer by Accumulation of CCR1+ Tumor-Associated Neutrophils through CCL15-CCR1 Axis (2016) (54)
- Cholinergically stimulated gastric acid secretion is mediated by M(3) and M(5) but not M(1) muscarinic acetylcholine receptors in mice. (2005) (54)
- The threshold level of adenomatous polyposis coli protein for mouse intestinal tumorigenesis. (2005) (53)
- Apc modulates embryonic stem-cell differentiation by controlling the dosage of β-catenin signaling (2003) (53)
- Destruction of Pancreatic β-Cells by Transgenic Induction of Prostaglandin E2 in the Islets* (2006) (53)
- Low wnt/β-catenin signaling determines leaky vessels in the subfornical organ and affects water homeostasis in mice (2019) (52)
- Reduced level of smoothened suppresses intestinal tumorigenesis by down-regulation of Wnt signaling. (2009) (50)
- Imaging Cyclooxygenase-2 (Cox-2) Gene Expression in Living Animals with a Luciferase Knock-in Reporter Gene (2006) (50)
- Mammalian Target of Rapamycin Is a Therapeutic Target for Murine Ovarian Endometrioid Adenocarcinomas with Dysregulated Wnt/β-Catenin and PTEN (2011) (49)
- Conditional mutations of beta-catenin and APC reveal roles for canonical Wnt signaling in lens differentiation. (2009) (48)
- The stabilization of beta-catenin leads to impaired primordial germ cell development via aberrant cell cycle progression. (2006) (48)
- Stabilised beta-catenin in postnatal ventricular myocardium leads to dilated cardiomyopathy and premature death (2010) (48)
- The mouse Rxrb gene encoding RXR beta: genomic organization and two mRNA isoforms generated by alternative splicing of transcripts initiated from CpG island promoters. (1994) (48)
- Embryonic hair follicle fate change by augmented β-catenin through Shh and Bmp signaling (2009) (48)
- Reflections on the Spread of Metastasis to Cancer Prevention (2011) (47)
- Impaired gastric secretion and lack of trophic responses to hypergastrinemia in M3 muscarinic receptor knockout mice. (2003) (47)
- Canonical Wnt signaling induces BMP-4 to specify slow myofibrogenesis of fetal myoblasts (2013) (47)
- CDC42 inhibition suppresses progression of incipient intestinal tumors. (2014) (46)
- Chromosomal instability by beta-catenin/TCF transcription in APC or beta-catenin mutant cells. (2007) (46)
- mTORC1-Mediated Inhibition of 4EBP1 Is Essential for Hedgehog Signaling-Driven Translation and Medulloblastoma. (2017) (45)
- Loss of anti-cataleptic effect of scopolamine in mice lacking muscarinic acetylcholine receptor subtype 4. (2003) (45)
- Autogenous regulation of RNA polymerase beta subunit synthesis in vitro. (1978) (45)
- A Targeted Mutation of Nkd1 Impairs Mouse Spermatogenesis* (2005) (45)
- Keratin-8 null mice have different gallbladder and liver susceptibility to lithogenic diet-induced injury (2003) (44)
- β-Catenin signaling specifies progenitor cell identity in parallel with Shh signaling in the developing mammalian thalamus (2012) (44)
- Effects of muscarinic receptor type 3 knockout on mouse islet secretory responses. (2004) (44)
- Intestinal cancer progression by mutant p53 through the acquisition of invasiveness associated with complex glandular formation (2017) (44)
- K-Ras and β-catenin mutations cooperate with Fgfr3 mutations in mice to promote tumorigenesis in the skin and lung, but not in the bladder (2011) (44)
- Roles of M2 and M4 muscarinic receptors in regulating acetylcholine release from myenteric neurons of mouse ileum. (2005) (44)
- CTNNB1 in mesenchyme regulates epithelial cell differentiation during Müllerian duct and postnatal uterine development. (2013) (43)
- β-Catenin gain of function in muscles impairs neuromuscular junction formation (2012) (41)
- Stabilized beta-catenin in lung epithelial cells changes cell fate and leads to tracheal and bronchial polyposis. (2009) (41)
- Activated renal tubular Wnt/β-catenin signaling triggers renal inflammation during overload proteinuria. (2018) (41)
- Beta-catenin (CTNNB1) induces Bmp expression in urogenital sinus epithelium and participates in prostatic bud initiation and patterning. (2013) (40)
- LKB1 Suppresses p21-activated Kinase-1 (PAK1) by Phosphorylation of Thr109 in the p21-binding Domain* (2010) (40)
- Canonical Wnt signaling regulates smooth muscle precursor development in the mouse ureter (2012) (40)
- Suppression of colonic polyposis by homeoprotein CDX2 through its nontranscriptional function that stabilizes p27Kip1. (2011) (40)
- A novel mouse model demonstrates that oncogenic melanocyte stem cells engender melanoma resembling human disease (2019) (40)
- Hepatocellular carcinoma development induced by conditional β‐catenin activation in Lkb1+/− mice (2009) (40)
- Spatially Restricted Stromal Wnt Signaling Restrains Prostate Epithelial Progenitor Growth through Direct and Indirect Mechanisms. (2019) (39)
- Wnt signaling has opposing roles in the developing and the adult brain that are modulated by Hipk1. (2012) (39)
- SMAD4 Suppresses WNT-Driven Dedifferentiation and Oncogenesis in the Differentiated Gut Epithelium. (2018) (39)
- Genomic organization, expression, and chromosomal mapping of the mouse adrenomedullin gene. (1996) (38)
- Differentiation-defective mutants of mouse embryonal carcinoma cells: response to hexamethylenebisacetamide and retinoic acid. (1983) (38)
- APC gene messenger RNA: novel isoforms that lack exon 7. (1993) (38)
- Epicardial function of canonical Wnt-, Hedgehog-, Fgfr1/2-, and Pdgfra-signalling. (2013) (38)
- Composite regulation of ERK activity dynamics underlying tumour-specific traits in the intestine (2018) (38)
- The WNT/MYB pathway suppresses KIT expression to control the timing of salivary proacinar differentiation and duct formation (2016) (38)
- JNK signaling promotes intestinal tumorigenesis through activation of mTOR complex 1 in Apc(Δ716) mice. (2011) (38)
- Optic cup and facial patterning defects in ocular ectoderm β-catenin gain-of-function mice (2006) (38)
- Keeping out the bad guys: gateway to cellular target therapy. (2007) (38)
- Impaired extrapyramidal function caused by the targeted disruption of Retinoid X receptor RXRγ1 isoform (1999) (37)
- β-Catenin stabilization in skeletal muscles, but not in motor neurons, leads to aberrant motor innervation of the muscle during neuromuscular development in mice. (2012) (37)
- Blocking TGF-β and β-Catenin Epithelial Crosstalk Exacerbates CKD. (2017) (37)
- Lineage tracing and targeting of IL17RB+ tuft cell-like human colorectal cancer stem cells (2019) (36)
- Ectopic Wnt/Beta–Catenin Signaling Induces Neurogenesis in the Spinal Cord and Hindbrain Floor Plate (2012) (35)
- Tissue-specific transgenic, conditional knockout and knock-in mice of genes in the canonical Wnt signaling pathway. (2008) (35)
- Uncoupling of macrophage inflammation from self-renewal modulates host recovery from respiratory viral infection (2021) (34)
- Gastro-intestinal tumorigenesis in Smad4 mutant mice. (2000) (33)
- Simultaneous expression of COX-2 and mPGES-1 in mouse gastrointestinal hamartomas (2004) (33)
- A Critical Role of Presynaptic Cadherin/Catenin/p140Cap Complexes in Stabilizing Spines and Functional Synapses in the Neocortex (2017) (33)
- Suppressing neutrophil-dependent angiogenesis abrogates resistance to anti-VEGF antibody in a genetic model of colorectal cancer (2020) (33)
- Runx3 Is Required for Full Activation of Regulatory T Cells To Prevent Colitis-Associated Tumor Formation (2011) (33)
- Effects of arotinoids upon murine embryonal carcinoma cells. (1983) (33)
- A mouse model for embryonal tumors with multilayered rosettes uncovers the therapeutic potential of Sonic-hedgehog inhibitors (2017) (32)
- Beta-Catenin Causes Adrenal Hyperplasia by Blocking Zonal Transdifferentiation (2020) (32)
- Non-steroidal anti-inflammatory drug indometacin enhances endogenous remyelination (2015) (31)
- Control of Formation of RNA Polymerase in Escherichia coli (1976) (31)
- Accelerated onsets of gastric hamartomas and hepatic adenomas/carcinomas in Lkb1+/−p53−/− compound mutant mice (2006) (31)
- Matrix metalloproteinase 7 is required for tumor formation, but dispensable for invasion and fibrosis in SMAD4-deficient intestinal adenocarcinomas (2009) (31)
- Isolation of embryonal carcinoma cell lines that express integrated recombinant genes flanked by the Moloney murine leukemia virus long terminal repeat. (1985) (30)
- No effects of Smad2 (madh2) null mutation on malignant progression of intestinal polyps in Apc(delta716) knockout mice. (2002) (30)
- Wnt/β-catenin signaling contributes to articular cartilage homeostasis through lubricin induction in the superficial zone (2019) (30)
- Focal Müllerian duct retention in male mice with constitutively activated β-catenin expression in the Müllerian duct mesenchyme (2010) (30)
- Overactive Beta-Catenin Signaling Causes Testicular Sertoli Cell Tumor Development in the Mouse1 (2009) (30)
- CDX transcription factors positively regulate expression of solute carrier family 5, member 8 in the colonic epithelium. (2010) (29)
- Molecular mechanisms of liver metastasis (2011) (29)
- Col1a1-cre mediated activation of β-catenin leads to aberrant dento-alveolar complex formation (2012) (28)
- Wnt/&bgr;-Catenin Signaling Maintains the Mesenchymal Precursor Pool for Murine Sinus Horn Formation (2011) (28)
- Excessive Wnt/beta-catenin signaling promotes midbrain floor plate neurogenesis, but results in vacillating dopamine progenitors (2015) (28)
- Mapping of the genes encoding mouse thromboxane A2 receptor and prostaglandin E receptor subtypes EP2 and EP3. (1994) (28)
- Effects of 2‐amino‐1‐methyl‐6‐phenylimidazo[4,5‐b]pyridine on intestinal polyp development in ApcΔ716 knockout mice (1996) (27)
- Dissecting Wnt Signaling for Melanocyte Regulation during Wound Healing. (2018) (27)
- Reducing DNA methylation suppresses colon carcinogenesis by inducing tumor cell differentiation. (2015) (27)
- Tumor microenvironment confers mTOR inhibitor resistance in invasive intestinal adenocarcinoma (2017) (27)
- Effects of docosahexaenoic acid (DHA) on intestinal polyp development in Apc delta 716 knockout mice. (1995) (27)
- Aberrant expression of a β-catenin gain-of-function mutant induces hyperplastic transformation in the mouse cornea (2010) (26)
- Development of spontaneous tumours and intestinal lesions in Fhit gene knockout mice (2004) (26)
- Summary β-Catenin regulates Cripto-and Wnt 3-dependent gene expression programs in mouse axis and mesoderm formation (26)
- Loss of Borealin/DasraB leads to defective cell proliferation, p53 accumulation and early embryonic lethality (2008) (26)
- Mapping of the mouse Rxr loci encoding nuclear retinoid X receptors RXR alpha, RXR beta, and RXR gamma. (1992) (26)
- Disruption of lineage specification in adult pulmonary mesenchymal progenitor cells promotes microvascular dysfunction (2017) (26)
- Induction of prostaglandin E2 pathway promotes gastric hamartoma development with suppression of bone morphogenetic protein signaling. (2009) (26)
- beta-Catenin Regulates Intercellular Signalling Networks and Cell-Type Specific Transcription in the Developing Mouse Midbrain-Rhombomere 1 Region (2010) (25)
- Gastrointestinal tumorigenesis in Smad4 (Dpc4) mutant mice. (2000) (25)
- Association of the 2-micron DNA plasmid with yeast folded chromosomes. (1980) (25)
- Estrogen-induced tumorigenesis in the pituitary gland of TGF-β(+/-) knockout mice (1998) (24)
- A cellular enhancer of retrovirus gene expression in embryonal carcinoma cells. (1987) (24)
- Mapping of eight testis-specific genes to mouse chromosomes. (1997) (24)
- Canonical Wnt signaling regulates the proliferative expansion and differentiation of fibrocytes in the murine inner ear. (2014) (24)
- Targeting β-Catenin in GLAST-Expressing Cells: Impact on Anxiety and Depression-Related Behavior and Hippocampal Proliferation (2018) (23)
- Canonical Wnt signaling regulates patterning, differentiation and nucleogenesis in mouse hypothalamus and prethalamus (2018) (23)
- TBX2 and TBX3 act downstream of canonical WNT signaling in patterning and differentiation of the mouse ureteric mesenchyme (2018) (23)
- Arid1a is essential for intestinal stem cells through Sox9 regulation (2019) (23)
- β-Catenin and FGFR2 regulate postnatal rosette-based adrenocortical morphogenesis (2020) (22)
- An improved method for culturing patient-derived colorectal cancer spheroids (2018) (22)
- Distinct Roles of HES1 in Normal Stem Cells and Tumor Stem-like Cells of the Intestine. (2017) (22)
- Hypergravity induces expression of cyclooxygenase-2 in the heart vessels. (2005) (21)
- Epithelial Wnt/βcatenin signalling is essential for epididymal coiling. (2016) (21)
- A New Cre Driver Mouse Line, Tcf21/Pod1-Cre, Targets Metanephric Mesenchyme (2012) (20)
- β-Catenin/TCF4 Complex-Mediated Induction of the NRF3 (NFE2L3) Gene in Cancer Cells (2019) (19)
- The possible involvement of tensin2 in the expression and extension of nephrin by glomerular podocytes in mice. (2008) (19)
- Muscarinic Agonist-Mediated Heterologous Desensitization in Isolated Ileum Requires Activation of Both Muscarinic M2 and M3 Receptors (2004) (19)
- IKKα promotes intestinal tumorigenesis by limiting recruitment of M1-like polarized myeloid cells. (2014) (19)
- Roles of stromal microenvironment in colon cancer progression. (2012) (19)
- Altered synthesis and stability of RNA polymerase holoenzyme subunits in mutants of Escherichia coli with mutations in the β or β′ subunit genes (1976) (19)
- Wnt/β-catenin activation cooperates with loss of p53 to cause adrenocortical carcinoma in mice (2020) (18)
- Antagonistic crosstalk of Wnt/beta-catenin/Bmp signaling within the Apical Ectodermal Ridge (AER) regulates interdigit formation. (2010) (18)
- Keratin 19 gene drives Cre recombinase expression throughout the early postimplantation mouse embryo (2005) (17)
- Adenomatous polyposis coli heterozygous knockout mice display hypoactivity and age-dependent working memory deficits (2011) (17)
- Role of bone marrow-derived cells in colon cancer: lessons from mouse model studies (2009) (17)
- Distinct populations within Isl1 lineages contribute to appendicular and facial skeletogenesis through the β-catenin pathway. (2014) (17)
- The role of mTORC1 pathway in intestinal tumorigenesis (2009) (16)
- Characterization of Mouse Retinoid X Receptor (RXR)-β Gene Promoter: Negative Regulation by Tumor Necrosis Factor (TNF)-α. (1998) (16)
- Ovarian insufficiency and CTNNB1 mutations drive malignant transformation of endometrial hyperplasia with altered PTEN/PI3K activities (2019) (16)
- Mouse thioredoxin gene maps on chromosome 4, whereas its pseudogene maps on chromosome 1. (1994) (16)
- Tcf7l1 protects the anterior neural fold from adopting the neural crest fate (2016) (16)
- Biosynthesis of RNA polymerase in Escherichia coli. V. Defects of the subunit assembly in a temperature-sensitive beta subunit mutant. (1977) (16)
- Wnt/β-Catenin Signaling Promotes Differentiation of Ischemia-Activated Adult Neural Stem/Progenitor Cells to Neuronal Precursors (2021) (15)
- Distribution of glycerolipid‐synthesizing enzymes in the subfractions of rat liver microsomes (1973) (15)
- A Chemosensitivity Study of Colorectal Cancer Using Xenografts of Patient-Derived Tumor-Initiating Cells (2018) (15)
- Erratum: Apc modulates embryonic stem-cell differentiation by controlling the dosage of β-catenin signaling (Nature Genetics (2002) 32 (594-605)) (2003) (15)
- Amino‐terminal enhancer of split gene AES encodes a tumor and metastasis suppressor of prostate cancer (2017) (14)
- Loss of SMAD 4 Promotes Colorectal Cancer Progression by Accumulation of Myeloid-Derived Suppressor Cells through the CCL 15 – CCR 1 Chemokine Axis (2016) (14)
- Mapping of five subtype genes for muscarinic acetylcholine receptor to mouse chromosomes. (1999) (14)
- β-Catenin signaling regulates the timing of cell differentiation in mouse retinal progenitor cells (2011) (14)
- Apc deficiency alters pulmonary epithelial cell fate and inhibits Nkx2.1 via triggering TGF-beta signaling. (2013) (14)
- Structure of the mouse thioredoxin-encoding gene and its processed pseudogene. (1995) (13)
- Stromal iodothyronine deiodinase 2 (DIO2) promotes the growth of intestinal tumors in Apc Δ716 mutant mice (2019) (13)
- Expression of metastasis suppressor gene AES driven by a Yin Yang (YY) element in a CpG island promoter and transcription factor YY2 (2016) (13)
- Deletions in a recombinant retrovirus genome associated with its expression in embryonal carcinoma cells (1989) (12)
- Genetic Interactions of the Androgen and Wnt/β-Catenin Pathways for the Masculinization of External Genitalia (2009) (12)
- Transgenic mice that accept Luciferase‐ or GFP‐expressing syngeneic tumor cells at high efficiencies (2018) (12)
- Manipulating Wnt signaling at different subcellular levels affects the fate of neonatal neural stem/progenitor cells (2016) (12)
- Mesothelial mobilization in the developing lung and heart differs in timing, quantity, and pathway dependency. (2019) (12)
- Hepatocyte specific expression of an oncogenic variant of β-catenin results in cholestatic liver disease (2016) (11)
- β‐catenin signaling modulates the tempo of dendritic growth of adult‐born hippocampal neurons (2020) (11)
- Synthetic lethality between MyD88 loss and mutations in Wnt/β-catenin pathway in intestinal tumor epithelial cells (2020) (10)
- Genomic structure and chromosomal location of the mouse macrophage C-type lectin gene (1999) (10)
- Constitutive Activation of β-Catenin in Conventional Dendritic Cells Increases the Insulin Reserve to Ameliorate the Development of Type 2 Diabetes in Mice (2019) (10)
- A novel transgenic mouse model of fetal encephalization and craniofacial development. (2008) (10)
- Disruption of CCR1-mediated myeloid cell accumulation suppresses colorectal cancer progression in mice. (2020) (9)
- Deleting the β-catenin degradation domain in mouse hepatocytes drives hepatocellular carcinoma or hepatoblastoma-like tumor growth. (2022) (9)
- Overactive beta-catenin signaling causes testicular sertoli cell tumor development in the mouse (Biology of Reproduction (2009) 81, (842-849) DOI: 10.1095/biolreprod.109.077446) (2010) (9)
- MicroRNA-9-5p-CDX2 Axis: A Useful Prognostic Biomarker for Patients with Stage II/III Colorectal Cancer (2019) (9)
- Dual blockade of macropinocytosis and asparagine bioavailability shows synergistic anti-tumor effects on KRAS-mutant colorectal cancer. (2021) (9)
- Physical mapping of the retinoid X receptorB gene in mouse and human (2004) (9)
- Gene structure and chromosome mapping of mouse transcription elongation factor S-II (Tcea1). (2000) (8)
- Identification of Aging-Associated Gene Expression Signatures That Precede Intestinal Tumorigenesis (2016) (8)
- Resident mesenchymal vascular progenitors modulate adaptive angiogenesis and pulmonary remodeling via regulation of canonical Wnt signaling (2020) (8)
- Antitumor activity of the MEK inhibitor trametinib on intestinal polyp formation in ApcΔ716 mice involves stromal COX-2 (2015) (8)
- Estrogen-induced tumorigenesis in the pituitary gland of TGF-beta(+/-) knockout mice. (1998) (8)
- Advances in Brief Gastrointestinal Hamartomatous Polyposis in Lkb 1 Heterozygous Knockout Mice 1 (2002) (8)
- The Müllerian inhibiting substance type 2 receptor suppresses tumorigenesis in testes with sustained β-catenin signaling. (2012) (8)
- Beta-catenin and estrogen signaling collaborate to drive cyclin D1 expression in developing mouse prostate. (2017) (8)
- Morphologic and molecular analysis of estrogen-induced pituitary tumorigenesis in targeted disruption of transforming growth factor-β receptor type II and/or p27 mice (2001) (8)
- β-Catenin gain of function in muscles impairs neuromuscular junction formation (2012) (8)
- Advances in Brief Hepatocellular Carcinoma Caused by Loss of Heterozygosity in Lkb 1 Gene Knockout Mice 1 (2002) (7)
- Mouse Elk oncogene maps to chromosome X and a novel Elk oncogene (Elk3) maps to chromosome 10. (1995) (7)
- Apc gene knockout mice as a model for familial adenomatous polyposis. (1999) (7)
- Comparative studies of RNA polymerase subunits from various bacteria (1977) (7)
- [COX inhibitor, suppression of polyposis, and chemoprevention]. (2002) (7)
- Tubular beta-catenin and FoxO3 interactions protect in chronic kidney disease. (2020) (7)
- Bone‐derived sclerostin and Wnt/β‐catenin signaling regulate PDGFRα+ adipoprogenitor cell differentiation (2021) (7)
- Biosynthesis of RNA polymerase in Escherichia coli (1978) (7)
- Loss of Pancreas upon Activated Wnt Signaling Is Concomitant with Emergence of Gastrointestinal Identity (2016) (7)
- Characterization of mouse retinoid X receptor (RXR)-beta gene promoter: negative regulation by tumor necrosis factor (TNF)-alpha. (1998) (6)
- Characterization of Aes nuclear foci in colorectal cancer cells. (2016) (6)
- Mapping of recombinant retrovirus integration sites that cause expression of the viral genome in murine embryonal carcinoma cells (2004) (6)
- Wnt inhibition promotes vascular specification of embryonic cardiac progenitors (2018) (6)
- Spatiotemporal reprogramming of differentiated cells underlies regeneration and neoplasia in the intestinal epithelium (2022) (5)
- Chemosensitivity of Patient-Derived Cancer Stem Cells Identifies Colorectal Cancer Patients with Potential Benefit from FGFR Inhibitor Therapy (2020) (5)
- Bone marrow sinusoidal endothelium controls terminal erythroid differentiation and reticulocyte maturation (2021) (5)
- Canonical Wnt/β-catenin activity and differential epigenetic marks direct sexually dimorphic regulation of Irx3 and Irx5 in developing mouse gonads (2020) (5)
- A Specific Nuclear DNA Background Is Required for High Frequency Lymphoma Development in Transmitochondrial Mice with G13997A mtDNA (2015) (5)
- Investigating the Role of Beta-Catenin in Sex Determination. (2008) (5)
- Id2 deletion attenuates Apc-deficient ileal tumor formation (2015) (5)
- Proteinuria-Induced Chronic Kidney Disease in the ICGN/Oa Mice with a Mutation of Tensin2 Gene (2009) (5)
- Hepatocyte specific expression of an oncogenic variant of β-catenin results in lethal metabolic dysfunction in mice (2018) (4)
- β-Catenin Role in the Vulnerability/Resilience to Stress-Related Disorders Is Associated to Changes in the Serotonergic System (2019) (4)
- Constitutive activation of canonical Wnt signaling disrupts choroid plexus epithelial fate (2022) (4)
- Mapping of six germ cell-specific genes to mouse chromosomes (2009) (4)
- Primary cilia control translation and the cell cycle in medulloblastoma (2022) (4)
- Gastric and Duodenal Polyps in Smad 4 ( Dpc 4 ) Knockout Mice 1 (1999) (4)
- Imbalanced Activation of Wnt-/β-Catenin-Signaling in Liver Endothelium Alters Normal Sinusoidal Differentiation (2021) (3)
- Biosynthesis of RNA polymerase in Escherichia coli. VII. Regulation of betabeta' operon on lambda transducing phage in assembly-defective mutants. (1978) (3)
- UvA-DARE ( Digital Academic Repository ) RSPO 1 / beta-Catenin Signaling Pathway Regulates Oogonia Differentiation and Entry into Meiosis in the Mouse Fetal Ovary Chassot (2017) (3)
- - 1-Increased Relaxant Action of Forskolin and Isoproterenol against Muscarinic Agonist-Induced Contractions in Smooth Muscle from M 2 Receptor Knockout Mice (2002) (3)
- A novel decellularized matrix of Wnt signaling-activated osteocytes accelerates the repair of critical-sized parietal bone defects with osteoclastogenesis, angiogenesis, and neurogenesis (2022) (3)
- Tubular β-catenin and FoxO3 interactions protect in chronic kidney disease (2020) (3)
- Control of the synthesis and assembly of RNA polymerase in Escherichia coli. (1976) (3)
- Accurate diagnosis of mismatch repair deficiency in colorectal cancer using high-quality DNA samples from cultured stem cells (2018) (3)
- Edar is a downstream target of beta-catenin and drives collagen accumulation in the mouse prostate (2019) (2)
- Concurrent activation of Kras and canonical Wnt signaling induces premalignant lesions that progress to extrahepatic biliary cancer in mice. (2022) (2)
- Mapping of the mouse Rar loci encoding retinoic acid receptors RARα, RARβ and RARγ (1993) (2)
- The cAMP/PKA/CREB and TGF-β/SMAD4 pathways regulate stemness and metastatic potential in colorectal cancer cells. (2022) (2)
- Gene organization and chromosome mapping of the testis-specific S-II (1998) (2)
- Blocking TGF-b and b-Catenin Epithelial Crosstalk Exacerbates CKD (2017) (2)
- Use of Genetically Engineered Mouse Models in Identification and Validation of Therapeutic Targets for Colon Cancer (2011) (2)
- Peptide analysis of RNA polymerase α subunit from Escherichia coli: Comparison of free with assembled form (1976) (2)
- Formation of RNA Polymerase in Escherichia coli (1977) (2)
- A novel parameter for cancer chemosensitivity to FGFR inhibitors. (2022) (2)
- Retrovirus integration site Mintb encoding the mouse homolog of hnRNP U. (1999) (2)
- Apc gene knockout mice, a model for human colorectal cancer (1997) (1)
- Fine-tuning of β-catenin in mouse thymic epithelial cells is required for postnatal T-cell development (2022) (1)
- Mullerian Mesenchyme-Specific Activation of Wnt/Beta-Catenin Signaling Inhibits Mullerian Duct Regression and Contributes to Male Infertility. (2010) (1)
- Studies on SV40 T antigen expression in wild-type and differentiation-defective murine embryonal carcinoma cell lines. (1982) (1)
- Mapping of the mouse Rar loci encoding retinoic acid receptors RAR alpha, RAR beta and RAR gamma. (1993) (1)
- MicroCT and microMRI imaging of a prenatal mouse model of increased brain size (2008) (1)
- Structures of mouse Rep-8 cDNA and genomic clones. (1999) (1)
- Progressive Spermatogonial Stem Cell Loss in Mice with Constitutively Activated Beta-Catenin in Postpubertal Sertoli Cells is Associated with Persistent Expression of GDNF and MIS. (2009) (1)
- - 1-Muscarinic Agonist-Mediated Heterologous Desensitization in Isolated Ileum Requires Activation of both Muscarinic M 2 and M 3 Receptors (2003) (1)
- Wnt/β-catenin activity is essential to turn the epigenetic state to "ON" in salivary gland stem cells to create cancer stem cells. (2010) (1)
- Canonical Wnt-signaling modulates the tempo of dendritic growth of adult-born hippocampal neurons (2020) (1)
- Title Carcinogenesis in Mouse Stomach by Simultaneous Activation of the WntSignaling and Prostaglandin E 2 Pathway (2017) (1)
- APC-mutant cells exploit compensatory chromosome alterations to restore tumour cell fitness (2020) (1)
- Targeting β-Catenin in GLAST-Expressing Cells: Impact on Anxiety and Depression-Related Behavior and Hippocampal Proliferation (2018) (1)
- Tumor and Stem Cell Biology KLF 5 Regulates the Integrity and Oncogenicity of Intestinal Stem Cells (2014) (1)
- Mouse Mak gene for male germ cell-associated kinase maps to chromosome 13. (1994) (1)
- Host inflammatory responses and gastrointestinal tumorigenesis (2006) (0)
- [Colon cancer and cyclooxygenase]. (1998) (0)
- Roles of thyroid hormone in intestinal tumorigenesis (2015) (0)
- Canonical Wnt signaling induces BMP-4 to specify slow myofibrogenesis of fetal myoblasts (2013) (0)
- MP41-08 AMINO-TERMINAL ENHANCER OF SPLIT/AES IS A TUMOR AND METASTASIS SUPPRESSOR OF PROSTATE CANCER (2014) (0)
- Wnt 4 / b 2 Catenin Signaling in Medullary Kidney (2013) (0)
- JCB_201405098 1..15 (2014) (0)
- Efficacious Combination Drug Treatment for Colorectal Cancer that Overcomes Resistance to KRAS G12C Inhibitors. (2023) (0)
- Deleting in vivo β-catenin degradation domain in mouse hepatocytes drives hepatocellular carcinoma or hepatoblastoma-like tumors (2021) (0)
- Title Composite regulation of ERK activity dynamics underlyingtumour-specific traits in the intestine (2018) (0)
- BIO012252 993..1001 (2015) (0)
- Abstract B23: Dominant stablized ss-catenin induces adenomyosis formation and ablation of Mig-6 accelerates progress of adenomyosis formation (2010) (0)
- Peutz-Jeghers polyposis Mucosal prolapse in the pathogenesis of (2006) (0)
- Abstract SY20-01: Role of Notch signaling in colon cancer invasion and metastasis (2014) (0)
- Resident Mesenchymal Vascular Progenitors Modulate the Pulmonary Microvascular Niche and Initiate the Development of Emphysema (2020) (0)
- Sobs Annual Report | | 2008 80 Primary (0)
- Colon cancer and polyposis models (2016) (0)
- Permissive ureter specification by TBX18-mediated repression of metanephric gene expression. (2023) (0)
- Apc de fi ciency alters pulmonary epithelial cell fate and inhibits Nkx 2 . 1 via triggering TGF-beta signaling (2013) (0)
- Identifying Mesenchymal Pathways That Initiate Emphysema in Order to Develop Targeted Therapies. (2018) (0)
- LB821 Critical role of Wnt signaling in follicular melanocyte stem cells (2016) (0)
- Studies on Colon Tumorigenesis and Therapy Using Apc Knockout Mice (1998) (0)
- Wnt signaling instructively promotes sensory neurogenesis in early neural crest stem cells (2005) (0)
- Title Antitumor activity of the MEK inhibitor trametinib on intestinal polyp formation in Apc [ Δ 716 ] mice involves stromal (2019) (0)
- 09-P038 Pax6 roles in lens development (2009) (0)
- Co-expression of phosphorylated ERK and stromal cell markers (2015) (0)
- The Role of β-catenin in Corneal Wound Healing (2009) (0)
- Colitis-Associated Tumor Formation Regulatory T Cells To Prevent Runx3 Is Required for Full Activation of (2011) (0)
- Canonical Wnt/β-catenin activity and differential epigenetic marks direct sexually dimorphic regulation of Irx3 and Irx5 in developing gonads. (2020) (0)
- Role of COX-2 in colon tumorigenesis (1999) (0)
- SPATIALLY-RESTRICTED STROMAL WNT SIGNALING RESTRAINS PROSTATE EPITHELIAL PROGENITOR PROLIFERATION THROUGH DIRECT AND INDIRECT MECHANISMS (2019) (0)
- Cyclooxygenase-2 Expression in Fibroblasts and Endothelial Cells of Intestinal Polyps 1 (2002) (0)
- Excessive Wnt/beta–catenin signaling promotes neurogenesis in the spinal cord, hindbrain, and midbrain floor plate, but results in vacillating dopamine progenitors (2011) (0)
- 287 Amino-terminal enhancer of split/AES is a tumor and metastasis suppressor of prostate cancer (2015) (0)
- No Effects of Smad2 ( Madh2 ) Null Mutation on Malignant Progression of Intestinal Polyps in Apc (cid:1) 716 Knockout Mice 1 (2002) (0)
- Enhanced Wnt Signaling in Adult Mesenchymal Vascular Progenitors Alters Adaptive Angiogenesis and Exacerbates the Development of Pulmonary Fibrosis (2020) (0)
- Multiple roles of mesenchymal (cid:2) -catenin during murine limb patterning (2006) (0)
- Successful Conclusion of the 8th PPCTSS (2009) (0)
- Roles of Smoothened (Smo), the major signal transducer of the hedgehog pathway, in the development of intestinal tumors (2008) (0)
- JB Review Roles of stromal microenvironment in colon cancer progression y (2012) (0)
- Frequent mutations that converge on the NFKBIZ pathway in ulcerative colitis (2019) (0)
- Suppression of intestinal cancer stemness and malignant progression by intestine-specific homeoproteins CDX1 and CDX2 (2016) (0)
- CXCR 3 ( chemokine ( CXC motif ) receptor 3 ) (2011) (0)
- β-Catenin signaling in alveolar macrophages enhances lung metastasis through a TNF-dependent mechanism. (2023) (0)
- The Role of ß–Catenin in Retinal Stem Cells and Retinal Development (2006) (0)
- Title Amino-terminal enhancer of split gene AES encodes a tumorand metastasis suppressor of prostate cancer (2019) (0)
- Targeting Asparagine Synthetase in Tumorgenicity Using Patient-Derived Tumor-Initiating Cells (2022) (0)
- 1379 Cell of origin contributes to the melanoma diversity (2018) (0)
- P1144 : Hepatocyte specific expression of a dominant stable form of beta-catenin results in cholestatic liver disease (2015) (0)
- ß–Catenin Signaling Regulates Maturation of Mouse Retinal Progenitor Cells by Preventing Premature Differentiation (2006) (0)
- Abstract 440: Dual role of epithelial MyD88 inApc-mutant intestinal tumors (2020) (0)
- 942 Hedgehog stimulates hair follicle neogenesis by creating inductive dermis during murine skin wound healing (2019) (0)
- Germline mutations in LKB 1 cause the rare cancer prone disorder (2005) (0)
- Constitutive activation of β-catenin signaling in embryonic surface epithelium results in global acquisition of hair follicle fate (2008) (0)
- Construction of transgenic mouse model for gastric cancer (2006) (0)
- Hepatocyte Specific Expression of a Dominant Stable Form of B-Catenin Results in Early Lethality Due to Disturbances in Lipid and Glucose Metabolism (2016) (0)
- Characterization of aaquetzalli (aqz), a gene required for development of the nervous system during Drosophila melanogaster embryogenesis (2011) (0)
- The role of chemokine receptor CXCR3 in colon cancer metastasis to lymph nodes (2008) (0)
- Abstract 3254: Promotion of colon cancer invasion and metastasis via activation of Notch-Dab1-Abl-RhoGEF protein Trio (2015) (0)
- Novel parameter for cancer chemosensitivity to fibroblast growth factor receptor inhibitors (2022) (0)
- Targeted engagement of β-catenin-Ikaros complexes in refractory B-cell malignancies (2023) (0)
- Wnt/ (cid:2) -catenin signaling controls development of the blood – brain barrier (2008) (0)
- State-of-the-Art Lecture: Of mice and men: mouse models for colon carcinogenesis (2006) (0)
- Deletions ina Recombinant Retrovirus GenomeAssociated withIts Expression inEmbryonal Carcinoma Cells (1989) (0)
- Myeloid-derived suppressor cells (MDSC) promotes colorectal cancer invasion through CCL15-CCR1 chemokine axis (2014) (0)
- Pax6 Is Required for the Differentiation of the Lens Fiber-Cells (2009) (0)
- β-Catenin and FGFR2 regulate postnatal rosette-based adrenocortical morphogenesis (2020) (0)
- beta-catenin activation regulates epithelial growth non-cell autonomously within the hair follicle stem cell niche (2014) (0)
- Confers Resistance to Differentiation-PromotingWnt / β-Catenin Signaling in Mouse Spermatogenic Stem Cells (2018) (0)
- Late Breaking Abstract - Novel mesenchymal pathways that initiate emphysema (2018) (0)
- Bmal1 Regulates Prostate Growth via Cell-Cycle Modulation (2022) (0)
- REVIEW Cyclooxygenase-2 Inhibitors in Tumorigenesis (Part II) (1998) (0)
- Abstract B65: Promotion of colorectal cancer invasion and metastasis through activation of Notch–Dab1–Abl–RhoGEF protein trio (2016) (0)
- Role of Bone Marrow-Derived CCR1+ cells in colon cancer invasion and metastasis (2015) (0)
- Spatially Restricted Strom al Wnt Signaling Restrains Prostate Epithelial Progenitor Growth throughDirect and Indirect Mechanisms Graphical (2019) (0)
- Enhanced intestinal mucosal barrier function by homeoprotein CDX2 through autophagy activation (2016) (0)
- Fine-tuning of β-catenin in thymic epithelial cells is required for postnatal T cell development (2021) (0)
- 1338 Dermal Wnt/β-catenin activation tunably controls hair follicle initiation (2018) (0)
- 664 Oncogenic melanocyte stem cells, driven by regenerative niche signals, give rise to heterogeneous melanoma resembling human melanoma (2020) (0)
- Canonical Wnt/β-catenin activity and differential epigenetic marks direct sexually dimorphic regulation of <italic>Irx3</italic> and <italic>Irx5</italic> in developing mouse gonads (2020) (0)
- Frizzled–5 Signaling During Mouse Eye Development (2006) (0)
- Title Wnt inhibition promotes vascular specification of embryoniccardiac progenitors (2019) (0)
- Title Loss of Pancreas upon Activated Wnt Signaling IsConcomitant with Emergence of Gastrointestinal Identity (2019) (0)
- [Intestinal polyposis in APC knockout mice: mechanism of tumorigenesis and chemotherapy]. (1999) (0)
- Chemokine Receptors Involved in Colon Cancer Progression, and Lymph Node Metastasis (2009) (0)
- Accumulation of the GSK3 target protein β-catenin is lethal for B cell precursors and malignant B cells (2021) (0)
- β-Catenin Role in the Vulnerability/Resilience to Stress-Related Disorders Is Associated to Changes in the Serotonergic System (2019) (0)
- CCR1-mediated accumulation of myeloid cells in the liver microenvironment promoting mouse colon cancer metastasis (2014) (0)
- Prostaglandin and Transforming Growth Factor β Signaling in Gastric Cancer (2009) (0)
- Canonical Wnt signaling exerts bidirectional control on choroid plexus epithelial development (2020) (0)
- The therapeutic potential of multiclonal tumoricidal T cells derived from tumor infiltrating lymphocyte-derived iPS cells (2021) (0)
- Composite regulation of ERK activity dynamics underlying tumour-specific traits in the intestine (2018) (0)
- WNT/β-catenin directed metabolic choice uncouples lung-resident alveolar macrophage inflammatory activity from self-renewal (2020) (0)
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What Schools Are Affiliated With Makoto Mark Taketo?
Makoto Mark Taketo is affiliated with the following schools:
