Makoto Murakami

Q: What Schools Are Affiliated With Makoto Murakami

Makoto Murakami is affiliated with the following schools: Shizuoka University, Kobe University, University of Tokyo, Showa University, Institute of Science Tokyo, Kyoto University, Sorbonne University, Harvard University

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Makoto Murakami

Computer Science

#6877

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#7243

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Computational Linguistics

#1283

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#1297

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Machine Learning

#2373

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#2402

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Artificial Intelligence

#2656

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#2697

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Computer Science

Makoto Murakami's Degrees

PhD Computer Science University of Tokyo
Masters Computer Science University of Tokyo
Bachelors Computer Science University of Tokyo

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Makoto Murakami's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Regulation of Prostaglandin E2 Biosynthesis by Inducible Membrane-associated Prostaglandin E2 Synthase That Acts in Concert with Cyclooxygenase-2* (2000) (985)
Phospholipase A2 enzymes. (2002) (726)
Molecular Identification of Cytosolic Prostaglandin E2 Synthase That Is Functionally Coupled with Cyclooxygenase-1 in Immediate Prostaglandin E2Biosynthesis* (2000) (706)
Recent progress in phospholipase A₂ research: from cells to animals to humans. (2011) (438)
Regulatory functions of phospholipase A2. (1997) (406)
The Lipid Mediator Protectin D1 Inhibits Influenza Virus Replication and Improves Severe Influenza (2013) (395)
The Functions of Five Distinct Mammalian Phospholipase A2s in Regulating Arachidonic Acid Release (1998) (384)
Functional Coupling Between Various Phospholipase A2s and Cyclooxygenases in Immediate and Delayed Prostanoid Biosynthetic Pathways* (1999) (361)
Cellular Prostaglandin E2 Production by Membrane-bound Prostaglandin E Synthase-2 via Both Cyclooxygenases-1 and -2* (2003) (354)
Mammalian non-pancreatic phospholipases A2. (1993) (344)
Recent advances in molecular biology and physiology of the prostaglandin E2-biosynthetic pathway. (2004) (322)
Reduced Pain Hypersensitivity and Inflammation in Mice Lacking Microsomal Prostaglandin E Synthase-1* (2004) (297)
Prostaglandin E synthase. (2002) (265)
Prostaglandin endoperoxide synthase-1 and -2 couple to different transmembrane stimuli to generate prostaglandin D2 in mouse bone marrow-derived mast cells. (1994) (236)
Fas-induced Arachidonic Acid Release Is Mediated by Ca2+-independent Phospholipase A2 but Not Cytosolic Phospholipase A2, Which Undergoes Proteolytic Inactivation* (1998) (232)
Biosynthesis of anandamide and N-palmitoylethanolamine by sequential actions of phospholipase A2 and lysophospholipase D. (2004) (228)
Exogenously Added Human Group X Secreted Phospholipase A2 but Not the Group IB, IIA, and V Enzymes Efficiently Release Arachidonic Acid from Adherent Mammalian Cells* (2000) (216)
Coupling between Cyclooxygenase, Terminal Prostanoid Synthase, and Phospholipase A2 * (2001) (205)
Secretory phospholipase A2. (2004) (198)
Molecular nature of phospholipases A2 involved in prostaglandin I2 synthesis in human umbilical vein endothelial cells. Possible participation of cytosolic and extracellular type II phospholipases A2. (1993) (197)
Cytosolic Phospholipase A2 Is Required for Cytokine-induced Expression of Type IIA Secretory Phospholipase A2 That Mediates Optimal Cyclooxygenase-2-dependent Delayed Prostaglandin E2 Generation in Rat 3Y1 Fibroblasts* (1998) (196)
Potential Role of Microsomal Prostaglandin E Synthase-1 in Tumorigenesis* (2003) (195)
Secreted phospholipase A2 revisited. (2011) (195)
Segregated coupling of phospholipases A2, cyclooxygenases, and terminal prostanoid synthases in different phases of prostanoid biosynthesis in rat peritoneal macrophages. (1998) (194)
Prostaglandin E synthase, a terminal enzyme for prostaglandin E2 biosynthesis. (2005) (185)
Distinct Arachidonate-releasing Functions of Mammalian Secreted Phospholipase A2s in Human Embryonic Kidney 293 and Rat Mastocytoma RBL-2H3 Cells through Heparan Sulfate Shuttling and External Plasma Membrane Mechanisms* (2001) (180)
Phospholipase A2. (2002) (179)
Distinct Roles of Two Intracellular Phospholipase A2s in Fatty Acid Release in the Cell Death Pathway (2000) (172)
Functional Association of Type IIA Secretory Phospholipase A2 with the Glycosylphosphatidylinositol-anchored Heparan Sulfate Proteoglycan in the Cyclooxygenase-2-mediated Delayed Prostanoid-biosynthetic Pathway* (1999) (172)
Concordant induction of prostaglandin E2 synthase with cyclooxygenase-2 leads to preferred production of prostaglandin E2 over thromboxane and prostaglandin D2 in lipopolysaccharide-stimulated rat peritoneal macrophages. (1997) (166)
A new era of secreted phospholipase A2 (2015) (165)
Different functional aspects of the group II subfamily (Types IIA and V) and type X secretory phospholipase A(2)s in regulating arachidonic acid release and prostaglandin generation. Implications of cyclooxygenase-2 induction and phospholipid scramblase-mediated cellular membrane perturbation. (1999) (163)
Transcriptional Regulation of the Membrane-associated Prostaglandin E2 Synthase Gene (2002) (156)
Diversity and regulatory functions of mammalian secretory phospholipase A2s. (2001) (150)
c-Kit Ligand Mediates Increased Expression of Cytosolic Phospholipase A, Prostaglandin Endoperoxide Synthase-1, and Hematopoietic Prostaglandin D Synthase and Increased IgE-dependent Prostaglandin D Generation in Immature Mouse Mast Cells (*) (1995) (150)
Prostaglandin E synthase: a novel drug target for inflammation and cancer. (2006) (142)
A new class of COX-2 inhibitor, rutaecarpine from Evodia rutaecarpa (1999) (140)
Prostaglandin E synthases: Understanding their pathophysiological roles through mouse genetic models. (2010) (138)
Type II Secretory Phospholipase A2 Associated with Cell Surfaces via C-terminal Heparin-binding Lysine Residues Augments Stimulus-initiated Delayed Prostaglandin Generation* (1996) (137)
Mast cells mediate neutrophil recruitment and vascular leakage through the NLRP3 inflammasome in histamine-independent urticaria (2009) (133)
Emerging roles of secreted phospholipase A2 enzymes: Lessons from transgenic and knockout mice. (2010) (132)
Lipid mediators in life science. (2011) (130)
Activation of Cytosolic Phospholipase A2 by Platelet-derived Growth Factor Is Essential for Cyclooxygenase-2-dependent Prostaglandin E2 Synthesis in Mouse Osteoblasts Cultured with Interleukin-1* (1997) (129)
Coupling between cyclooxygenases and terminal prostanoid synthases. (2005) (127)
Prostaglandin E2 Amplifies Cytosolic Phospholipase A2- and Cyclooxygenase-2-dependent Delayed Prostaglandin E2 Generation in Mouse Osteoblastic Cells (1997) (127)
Small RNA transcriptomes of two types of exosomes in human whole saliva determined by next generation sequencing. (2013) (127)
Analyses of Group III Secreted Phospholipase A2 Transgenic Mice Reveal Potential Participation of This Enzyme in Plasma Lipoprotein Modification, Macrophage Foam Cell Formation, and Atherosclerosis* (2008) (121)
Use of nisin for inhibition of Alicyclobacillus acidoterrestris in acidic drinks. (2000) (115)
Regulatory Functions of Phospholipase A2. (2017) (114)
Prostaglandin E2–EP3 Signaling Induces Inflammatory Swelling by Mast Cell Activation (2014) (113)
Characterization of a haemolytic factor from Candida albicans. (1999) (113)
Lysophosphatidylcholine acyltransferase 1 altered phospholipid composition and regulated hepatoma progression. (2013) (112)
The immediate phase of c-kit ligand stimulation of mouse bone marrow- derived mast cells elicits rapid leukotriene C4 generation through posttranslational activation of cytosolic phospholipase A2 and 5- lipoxygenase (1995) (111)
The perturbed membrane of cells undergoing apoptosis is susceptible to type II secretory phospholipase A2 to liberate arachidonic acid. (1997) (108)
Mast cell maturation is driven via a group III phospholipase A2-prostaglandin D2–DP1 receptor paracrine axis (2013) (102)
Lymphoid tissue phospholipase A2 group IID resolves contact hypersensitivity by driving antiinflammatory lipid mediators (2013) (101)
Critical role of phospholipase A2 group IID in age-related susceptibility to severe acute respiratory syndrome–CoV infection (2015) (101)
Release of secretory phospholipase A2 from rat neuronal cells and its possible function in the regulation of catecholamine secretion. (1996) (101)
Group III secreted phospholipase A2 regulates epididymal sperm maturation and fertility in mice. (2010) (98)
A Heparin-sensitive Phospholipase A2 and Prostaglandin Endoperoxide Synthase-2 Are Functionally Linked in the Delayed Phase of Prostaglandin D2 Generation in Mouse Bone Marrow-derived Mast Cells* (1996) (97)
Cellular components that functionally interact with signaling phospholipase A(2)s. (2000) (97)
PNPLA1 has a crucial role in skin barrier function by directing acylceramide biosynthesis (2017) (96)
Transgenic Expression of Group V, but Not Group X, Secreted Phospholipase A2 in Mice Leads to Neonatal Lethality because of Lung Dysfunction* (2006) (95)
Regulation of type V phospholipase A2 expression and function by proinflammatory stimuli. (1999) (94)
Triggering of degranulation in mast cells by exogenous type II phospholipase A2. (1993) (93)
RalA Functions as an Indispensable Signal Mediator for the Nutrient-sensing System* (2008) (92)
Identification of a Cellular Protein That Functionally Interacts with the C2 Domain of Cytosolic Phospholipase A2α* (2000) (92)
IgE-dependent activation of cytokine-primed mouse cultured mast cells induces a delayed phase of prostaglandin D2 generation via prostaglandin endoperoxide synthase-2. (1995) (92)
The adipocyte-inducible secreted phospholipases PLA2G5 and PLA2G2E play distinct roles in obesity. (2014) (90)
Eicosanoid generation from antigen‐primed mast cells by extracellular mammalian 14‐kDa group II phospholipase A2 (1991) (89)
Induction of cyclooxygenase-2 by secretory phospholipases A2 in nerve growth factor-stimulated rat serosal mast cells is facilitated by interaction with fibroblasts and mediated by a mechanism independent of their enzymatic functions. (1998) (89)
Release of 14-kDa group-II phospholipase A2 from activated mast cells and its possible involvement in the regulation of the degranulation process. (1992) (87)
Emodin, a naturally occurring anthraquinone derivative, suppresses IgE-mediated anaphylactic reaction and mast cell activation. (2011) (85)
Purification of rabbit platelet secretory phospholipase A2 and its characteristics. (1989) (85)
Expression of secretory phospholipase A2 enzymes in lungs of humans with pneumonia and their potential prostaglandin-synthetic function in human lung-derived cells. (2005) (85)
Emerging roles of secreted phospholipase A(2) enzymes: an update. (2013) (80)
Regulation of cytosolic prostaglandin E synthase by phosphorylation. (2004) (80)
New phospholipase A2 isozymes with a potential role in atherosclerosis (2003) (79)
Regulation of cytosolic prostaglandin E2 synthase by 90-kDa heat shock protein. (2003) (79)
Mouse bone marrow-derived mast cells undergo exocytosis, prostanoid generation, and cytokine expression in response to G protein-activating polybasic compounds after coculture with fibroblasts in the presence of c-kit ligand. (1997) (77)
Thermal resistance ofAlicyclobacillus acidoterrestrisspores in different buffers and pH (1998) (77)
Cellular Distribution, Post-translational Modification, and Tumorigenic Potential of Human Group III Secreted Phospholipase A2* (2005) (76)
Cellular Arachidonate-releasing Function of Novel Classes of Secretory Phospholipase A2s (Groups III and XII)* (2003) (76)
Diverse cellular localizations of secretory phospholipase A2 enzymes in several human tissues. (2005) (75)
Critical role of PICT-1, a tumor suppressor candidate, in phosphatidylinositol 3,4,5-trisphosphate signals and tumorigenic transformation. (2006) (75)
Expression of secretory phospholipase A2s in human atherosclerosis development. (2008) (74)
Induction of distinct sets of secretory phospholipase A(2) in rodents during inflammation. (2003) (72)
Detection of three distinct phospholipases A2 in cultured mast cells. (1992) (70)
Microsomal prostaglandin E synthase-1 in both cancer cells and hosts contributes to tumour growth, invasion and metastasis (2009) (69)
m-Calpain Induction in Vascular Endothelial Cells on Human and Mouse Atheromas and Its Roles in VE-Cadherin Disorganization and Atherosclerosis (2011) (69)
Neuronal Expression and Neuritogenic Action of Group X Secreted Phospholipase A2* (2005) (69)
Emerging roles of secreted phospholipase A2 enzymes: the 3rd edition. (2014) (69)
Cellular Arachidonate-releasing Function and Inflammation-associated Expression of Group IIF Secretory Phospholipase A2 * (2002) (68)
Various secretory phospholipase A2 enzymes are expressed in rheumatoid arthritis and augment prostaglandin production in cultured synovial cells (2005) (68)
Secretory phospholipases A2. (1995) (68)
Studies on a Mechanism by Which Cytosolic Phospholipase A2 Regulates the Expression and Function of Type IIA Secretory Phospholipase A21 (2000) (68)
Group X phospholipase A2 is released during sperm acrosome reaction and controls fertility outcome in mice. (2010) (66)
Participation in cellular prostaglandin synthesis of type-II phospholipase A2 secreted and anchored on cell-surface heparan sulfate proteoglycan. (1993) (65)
Updating Phospholipase A2 Biology (2020) (64)
Group VIB Ca2+-independent Phospholipase A2γ Promotes Cellular Membrane Hydrolysis and Prostaglandin Production in a Manner Distinct from Other Intracellular Phospholipases A2* (2005) (64)
Microsomal prostaglandin E synthase-1 is involved in multiple steps of colon carcinogenesis (2012) (63)
Human group III secreted phospholipase A2 promotes neuronal outgrowth and survival. (2008) (63)
Redundant and Segregated Functions of Granule-Associated Heparin-Binding Group II Subfamily of Secretory Phospholipases A2 in the Regulation of Degranulation and Prostaglandin D2 Synthesis in Mast Cells1 (2000) (62)
Group X Secreted Phospholipase A2 Limits the Development of Atherosclerosis in LDL Receptor–Null Mice (2013) (61)
The role of group IIF-secreted phospholipase A2 in epidermal homeostasis and hyperplasia (2015) (58)
Possible role of mammalian secretory group II phospholipase A2 in T-lymphocyte activation: implication in propagation of inflammatory reaction. (1993) (57)
Exacerbation of rat adjuvant arthritis by intradermal injection of purified mammalian 14‐kDa group II phospholipase A2 (1990) (55)
Arachidonate release and eicosanoid generation by group IIE phospholipase A(2). (2002) (54)
Role of cytosolic phospholipase A2 in the production of lipid mediators and histamine release in mouse bone-marrow-derived mast cells. (2000) (54)
Group X Secreted Phospholipase A2 Releases ω3 Polyunsaturated Fatty Acids, Suppresses Colitis, and Promotes Sperm Fertility* (2016) (54)
Group V and X secretory phospholipase A2 prevents adenoviral infection in mammalian cells. (2006) (53)
The Roles of the Secreted Phospholipase A2 Gene Family in Immunology (2016) (52)
Stabilization of mast cells by heme oxygenase-1: an anti-inflammatory role. (2002) (51)
Identification of NDRG1 as an early inducible gene during in vitro maturation of cultured mast cells. (2003) (51)
Induction of cyclooxygenase-2 causes an enhancement of writhing response in mice. (1998) (51)
Parkinson’s disease-associated iPLA2-VIA/PLA2G6 regulates neuronal functions and α-synuclein stability through membrane remodeling (2019) (50)
Immunochemical detection of 'platelet type' phospholipase A2 in the rat. (1990) (50)
PGD2 induces eotaxin-3 via PPARγ from sebocytes: a possible pathogenesis of eosinophilic pustular folliculitis. (2012) (50)
Strain differences in hepatic cytochrome P450 1A and 3A expression between Sprague-Dawley and Wistar rats. (2008) (50)
Efficient production of cellulolytic and xylanolytic enzymes by the rumen anaerobic fungus, Neocallimastix frontalis, in a repeated batch culture. (2001) (48)
Group III secreted phospholipase A2 transgenic mice spontaneously develop inflammation (2009) (48)
Lipoquality control by phospholipase A2 enzymes (2017) (47)
Phosphatidylethanolamine dynamics are required for osteoclast fusion (2017) (45)
Regulation of cyclooxygenase-2 and endogenous cytokine expression by bacterial lipopolysaccharide that acts in synergy with c-kit ligand and Fc epsilon receptor I crosslinking in cultured mast cells. (1998) (45)
Localization of various secretory phospholipase A2 enzymes in male reproductive organs. (2004) (45)
Physiological Roles of Group X-secreted Phospholipase A2 in Reproduction, Gastrointestinal Phospholipid Digestion, and Neuronal Function* (2011) (44)
Dual Roles of Group IID Phospholipase A2 in Inflammation and Cancer* (2016) (44)
Deficiency of Phospholipase A2 Receptor Exacerbates Ovalbumin-Induced Lung Inflammation (2013) (44)
Impaired Mast Cell Maturation and Degranulation and Attenuated Allergic Responses in Ndrg1-Deficient Mice1 (2007) (43)
A Novel Role of Group VIB Calcium-independent Phospholipase A2 (iPLA2γ) in the Inducible Expression of Group IIA Secretory PLA2 in Rat Fibroblastic Cells* (2007) (42)
Roles of endogenous prostaglandins and cyclooxygenase izoenzymes in mucosal defense of inflamed rat stomach. (2004) (41)
Mitochondrial dysfunction and reduced prostaglandin synthesis in skeletal muscle of Group VIB Ca2+-independent phospholipase A2γ-deficient mice[S] (2010) (40)
Establishment of the culture model system that reflects the process of terminal differentiation of connective tissue‐type mast cells (2008) (39)
Association of microsomal prostaglandin E synthase 1 deficiency with impaired fracture healing, but not with bone loss or osteoarthritis, in mouse models of skeletal disorders. (2008) (39)
N-myc downregulated gene 1 is a phosphorylated protein in mast cells. (2004) (39)
Direct conversion of cellulose to methane by anaerobic fungus Neocallimastix frontalis and defined methanogens (2000) (39)
Metabolic regulation by secreted phospholipase A2 (2016) (39)
Interleukin 4 suppresses c-kit ligand-induced expression of cytosolic phospholipase A2 and prostaglandin endoperoxide synthase 2 and their roles in separate pathways of eicosanoid synthesis in mouse bone marrow-derived mast cells. (1995) (38)
Papyriflavonol A from Broussonetia papyrifera inhibits the passive cutaneous anaphylaxis reaction and has a secretory phospholipase A2-inhibitory activity. (2003) (38)
Omega-3 fatty acid epoxides are autocrine mediators that control the magnitude of IgE-mediated mast cell activation (2017) (38)
Neuropeptide Y content in the hypothalamic paraventricular nucleus responds to fasting and refeeding in broiler chickens. (2005) (38)
Cyclooxygenase-2-dependent delayed prostaglandin D2 generation is initiated by nerve growth factor in rat peritoneal mast cells: its augmentation by extracellular type II secretory phospholipase A2. (1997) (38)
Eicosanoid signalling blockade protects middle-aged mice from severe COVID-19 (2022) (37)
Contribution of membrane‐associated prostaglandin E2 synthase to bone resorption (2003) (37)
Cross-linking of the high-affinity IgE receptor induces the expression of cyclo-oxygenase 2 and attendant prostaglandin generation requiring interleukin 10 and interleukin 1 beta in mouse cultured mast cells. (1996) (37)
Arachidonate release and prostaglandin production by group IVC phospholipase A2 (cytosolic phospholipase A2gamma). (2003) (37)
Dual regulation of cytosolic phospholipase A2 in mast cells after cross-linking of FC epsilon-receptor. (1994) (37)
Activated Mast Cells Release Extracellular Type Platelet-activating Factor Acetylhydrolase That Contributes to Autocrine Inactivation of Platelet-activating Factor* (1997) (37)
Monoclonal antibodies against rat platelet phospholipase A2. (1988) (36)
The role of PNPLA1 in ω-O-acylceramide synthesis and skin barrier function. (2019) (36)
Novel functions of phospholipase A2s: Overview. (2019) (36)
CHARACTERIZATION OF CYTOCHROME P450 EXPRESSION IN MURINE EMBRYONIC STEM CELL-DERIVED HEPATIC TISSUE SYSTEM (2006) (35)
Oligo‐astheno‐teratozoospermia in mice lacking ORP4, a sterol‐binding protein in the OSBP‐related protein family (2014) (35)
Group II phospholipase A2 inhibitors suppressed lysophosphatidylserine-dependent degranulation of rat peritoneal mast cells. (1991) (35)
In vivo release and clearance of rat platelet phospholipase A2. (1989) (34)
Autotaxin–lysophosphatidic acid–LPA 3 signaling at the embryo‐epithelial boundary controls decidualization pathways (2017) (33)
Calpastatin counteracts pathological angiogenesis by inhibiting suppressor of cytokine signaling 3 degradation in vascular endothelial cells. (2015) (33)
Matrix Metalloproteinase‐2 Negatively Regulates Cardiac Secreted Phospholipase A2 to Modulate Inflammation and Fever (2015) (32)
Human group III phospholipase A2 suppresses adenovirus infection into host cells. Evidence that group III, V and X phospholipase A2s act on distinct cellular phospholipid molecular species. (2007) (32)
Association of N-myc downregulated gene 1 with heat-shock cognate protein 70 in mast cells. (2004) (32)
AMP-activated protein kinase negatively regulates FcεRI-mediated mast cell signaling and anaphylaxis in mice. (2013) (32)
Diverse functional coupling of prostanoid biosynthetic enzymes in various cell types. (1999) (31)
Secreted phospholipase A2, lipoprotein hydrolysis, and atherosclerosis: integration with lipidomics (2011) (30)
Expression of type V secretory phospholipase A2 in myocardial remodelling after infarction (2005) (30)
Secreted Phospholipase PLA2G2D Contributes to Metabolic Health by Mobilizing ω3 Polyunsaturated Fatty Acids in WAT. (2020) (29)
Polyunsaturated fatty acids potentiate interleukin‐1‐stimulated arachidonic acid release by cells overexpressing type IIA secretory phospholipase A2 (1999) (29)
Secreted phospholipase A2 and mast cells. (2015) (29)
Lack of Phospholipase A2 Receptor Increases Susceptibility to Cardiac Rupture After Myocardial Infarction (2014) (29)
Immunochemical detection of arachidonoyl-preferential phospholipase A2. (1992) (28)
Hot topics in phospholipase A2 field. (2004) (28)
Group IID heparin-binding secretory phospholipase A(2) is expressed in human colon carcinoma cells and human mast cells and up-regulated in mouse inflammatory tissues. (2002) (27)
Agonist stimulation of B1 and B2 kinin receptors causes activation of the MAP kinase signaling pathway, resulting in the translocation of AP‐1 in HEK 293 cells (1998) (26)
Unique Membrane Interaction Mode of Group IIF Phospholipase A2* (2006) (26)
Activation of inflammation and resolution pathways of lipid mediators in synovial fluid from patients with severe rheumatoid arthritis compared with severe osteoarthritis (2020) (26)
Hair Follicular Expression and Function of Group X Secreted Phospholipase A2 in Mouse Skin* (2011) (26)
NecroX‐5 suppresses IgE/Ag‐stimulated anaphylaxis and mast cell activation by regulating the SHP‐1‐Syk signaling module (2016) (25)
ERK1/2 antagonize AMPK-dependent regulation of FcεRI-mediated mast cell activation and anaphylaxis. (2014) (25)
Functional coupling between various phospholipase A_2s and cyclooxygenases in immediate and delayed prostanoid biosynthetic pathway (2001) (25)
Perinuclear localization of cytosolic phospholipase A2α is important but not obligatory for coupling with cyclooxygenases (2003) (25)
Characteristics and pathophysiological roles of extracellular phospholipase A2 in inflamed sites. (1989) (25)
Secreted Phospholipase A2 Specificity on Natural Membrane Phospholipids. (2017) (24)
Group III phospholipase A2 promotes colitis and colorectal cancer (2017) (24)
Change in prostaglandin E synthases (PGESs) in microsomal PGES-1 knockout mice in a preterm delivery model. (2005) (24)
Eicosanoid signaling as a therapeutic target in middle-aged mice with severe COVID-19 (2021) (23)
Group VIB Calcium-Independent Phospholipase A2 (iPLA2γ) Regulates Platelet Activation, Hemostasis and Thrombosis in Mice (2014) (23)
Distribution of type V secretory phospholipase A2 expression in human hepatocytes damaged by liver disease (2004) (23)
Sirt1 negatively regulates FcεRI-mediated mast cell activation through AMPK- and PTP1B-dependent processes (2017) (23)
Internalization and degradation of type IIA phospholipase A(2) in mast cells. (2000) (23)
Leukotriene B4 receptor type 2 protects against pneumolysin-dependent acute lung injury (2016) (22)
Phospholipase D is involved in cytosolic phospholipase A2‐dependent selective release of arachidonic acid by fMLP‐stimulated rat neutrophils (1996) (22)
Search of Factors That Intermediate Cytokine-induced Group IIA Phospholipase A2 Expression through the Cytosolic Phospholipase A2- and 12/15-Lipoxygenase-dependent Pathway* (2005) (21)
Age-dependent appearance of NK1.1+ T cells in the livers of beta2-microglobulin knockout and SJL mice. (1998) (21)
Group IID, IIE, IIF and III secreted phospholipase A2s☆ (2018) (21)
Analysis of Two Major Intracellular Phospholipases A2 (PLA2) in Mast Cells Reveals Crucial Contribution of Cytosolic PLA2α, Not Ca2+-independent PLA2β, to Lipid Mobilization in Proximal Mast Cells and Distal Fibroblasts* (2011) (21)
Critical role for cytosolic group IVA phospholipase A2 in early adipocyte differentiation and obesity. (2016) (21)
Tanshinone IIA suppresses Fc&egr;RI‐mediated mast cell signaling and anaphylaxis by activation of the Sirt1/LKB1/AMPK pathway (2018) (21)
Distribution of smooth muscle cells and macrophages expressing scavenger receptor BI/II in atherosclerosis. (2009) (21)
Citreorosein, a naturally occurring anthraquinone derivative isolated from Polygoni cuspidati radix, attenuates cyclooxygenase-2-dependent prostaglandin D2 generation by blocking Akt and JNK pathways in mouse bone marrow-derived mast cells. (2012) (20)
Functional crosstalk between phospholipase D2 and signaling phospholipase A2/cyclooxygenase‐2‐mediated prostaglandin biosynthetic pathways (2000) (20)
Detection of secretory phospholipase A2s related but not identical to type IIA isozyme in cultured mast cells (1997) (20)
Role of type IIA secretory phospholipase A2 in arachidonic acid metabolism. (1999) (20)
Degranulation and cytokine expression in human cord blood-derived mast cells cultured in serum-free medium with recombinant human stem cell factor. (2003) (20)
Butyrate inhibits oral cancer cell proliferation and regulates expression of secretory phospholipase A2-X and COX-2. (2007) (19)
Expression and Function of Group IIE Phospholipase A2 in Mouse Skin* (2016) (18)
Different Functional Aspects of the Group II Subfamily (Types IIA and V) and Type X Secretory Phospholipase A2s in Regulating Arachidonic Acid Release and Prostaglandin Generation (1999) (18)
Coupling between cyclooxygenases and prostaglandin F2α synthase: Detection of an inducible, glutathione-activated, membrane-bound prostaglandin F2α-synthetic activity (2003) (18)
Type II phospholipase A2 is linked to cyclooxygenase-2-mediated delayed prostaglandin D2 generation by cultured mouse mast cells following FcepsilonRI- and cytokine-dependent activation. (1996) (18)
Primary cilium suppression by SREBP1c involves distortion of vesicular trafficking by PLA2G3 (2015) (17)
An anti-sulfatide antibody O4 immunoprecipitates sulfatide rafts including Fyn, Lyn and the G protein α subunit in rat primary immature oligodendrocytes (2013) (16)
Prostaglandin E2-EP4 Axis Promotes Lipolysis and Fibrosis in Adipose Tissue Leading to Ectopic Fat Deposition and Insulin Resistance. (2020) (16)
Role of type II phospholipase A2 in the inflammatory process of carrageenan‐induced pleurisy in rats (1994) (15)
Secreted phospholipase A2 modifies extracellular vesicles and accelerates B cell lymphoma. (2022) (15)
Monoclonal antibodies against human synovial phospholipase A2. (1990) (15)
Function of type II phospholipase A2 in dopamine secretion by rat neuronal PC12 cells. (1996) (14)
Phospholipase A2 in skin biology: new insights from gene-manipulated mice and lipidomics (2018) (14)
Induction of PYPAF1 during in vitro maturation of mouse mast cells. (2003) (14)
Group IIA secretory phospholipase A2 is a unique 12/15-lipoxygenase-regulated gene in cytokine-stimulated rat fibroblastic 3Y1 cells. (2004) (14)
The interaction of secreted phospholipase A2-IIA with the microbiota alters its lipidome and promotes inflammation (2022) (14)
Autophagy Is Required for Maturation of Surfactant-Containing Lamellar Bodies in the Lung and Swim Bladder. (2020) (13)
Group V secreted phospholipase A2 plays a protective role against aortic dissection (2020) (12)
The orphan nuclear receptor NR4A1 promotes FcεRI‐stimulated mast cell activation and anaphylaxis by counteracting the inhibitory LKB1/AMPK axis (2019) (12)
Saucerneol D inhibits eicosanoid generation and degranulation through suppression of Syk kinase in mast cells. (2012) (12)
Red-kerneled rice proanthocyanidin inhibits arachidonate 5-lipoxygenase and decreases psoriasis-like skin inflammation. (2020) (11)
Dynamics and participation of type II phospholipase A2 in rat zymosan-induced pleurisy. (1993) (11)
Coronavirus-specific antibody production in middle-aged mice requires phospholipase A2G2D. (2021) (10)
Functional coupling between phospholipase A2S and cyclooxygenases in immediate and delayed prostanoid biosynthetic pathways. (2002) (10)
Upregulation of ANGPTL6 in mouse keratinocytes enhances susceptibility to psoriasis (2016) (10)
Integrated Lipidomics in the Secreted Phospholipase A2 Biology (2011) (10)
Group IIA secreted phospholipase A2 controls skin carcinogenesis and psoriasis by shaping the gut microbiota (2022) (10)
Mast cells mediate neutrophil recruitment and vascular leakage through the NLRP3 inflammasome in histamine-independent urticaria (2009) (10)
Change in phospholipid composition of mouse bone marrow-derived mast cells during cultivation with fibroblasts. (1992) (10)
Glycoconjugates with NeuAc-NeuAc-Gal-Glc are more effective at preventing adhesion of Helicobacter pylori to gastric epithelial cells than glycoconjugates with NeuAc-Gal-Glc. (2004) (10)
Phospholipase A2 Group III and Group X Have Opposing Associations with Prognosis in Colorectal Cancer. (2015) (9)
Citreorosein inhibits production of proinflammatory cytokines by blocking mitogen activated protein kinases, nuclear factor-κB and activator protein-1 activation in mouse bone marrow-derived mast cells. (2012) (9)
Altered cytokine expression in mesenteric lymph nodes in a rat strain (Matsumoto Eosinophilic Shinshu) that spontaneously develops hypereosinophilia (2005) (9)
A Gastrointestinal Calpain Complex, G-calpain, Is a Heterodimer of CAPN8 and CAPN9 Calpain Isoforms, Which Play Catalytic and Regulatory Roles, Respectively* (2016) (9)
Effects of indomethacin and rofecoxib on gastric mucosal damage in normal and Helicobacter pylori-infected mongolian gerbils. (2004) (9)
The expression of phospholipase A2 group X is inversely associated with metastasis in colorectal cancer (2012) (8)
Exogenous type-II phospholipase A2 stimulates prostaglandin synthesis in rat liver-derived BRL-3A cells in the presence of tumor necrosis factor alpha. (1995) (8)
Coupling between cyclooxygenases and prostaglandin F(2alpha) synthase. Detection of an inducible, glutathione-activated, membrane-bound prostaglandin F(2alpha)-synthetic activity. (2003) (8)
Cellular arachidonate-releasing functions of various phospholipase A2s. (2003) (8)
Old but New: Group IIA Phospholipase A2 as a Modulator of Gut Microbiota (2022) (7)
Saucerneol F inhibits tumor necrosis factor-α and IL-6 production by suppressing Fyn-mediated pathways in FcεRI-mediated mast cells. (2013) (7)
Characterization of heparin low-affinity phospholipase A1 present in brain and testicular tissue. (1999) (7)
Polyunsaturated fatty acids potentiate interleukin-1-stimulated arachidonic acid release by cells overexpressing type IIA secretory phospholipase A 2 (1999) (7)
Group IVE cytosolic phospholipase A2 limits psoriatic inflammation by mobilizing the anti‐inflammatory lipid N‐acylethanolamine (2022) (7)
Regulatory functions of prostaglandin E2 synthases. (2003) (7)
Preventive effect of Dioscorea japonica on squamous cell carcinoma of mouse skin involving down-regulation of prostaglandin E2 synthetic pathway (2018) (6)
Change in sensitivity to lysophosphatidylserine of mouse bone marrow-derived mast cells during cultivation with fibroblasts. (1991) (6)
Phospholipase A 2 (2015) (6)
Diversity of Phospholipase A 2 Enzymes (6)
[Lipid networks in mast cell biology]. (2011) (6)
Cytosolic Phospholipase A2a Interacts With Microtubules (2002) (6)
Cytokine Regulation of Mast Cell Protease Phenotype and Arachidonic Acid Metabolism (1994) (6)
Tissue- and dose-dependent alteration of stress-inducible proteins by beta2-adrenoceptor agonist, salbutamol, in rats. (2005) (5)
A new restriction endonuclease from Acetobacter pasteurianus (ApaLI). (1985) (5)
Anti-inflammatory activity of hexane extracts from bones and internal organs of Anguilla japonica suppresses cyclooxygenase-2-dependent prostaglandin D₂ generation in mast cells and anaphylaxis in mice. (2013) (5)
Critical amino acids responsible for converting specificities of proteins and for enhancing enzyme evolution are located around β-turn potentials: Data-based prediction (1993) (5)
A negative regulator of delayed prostaglandin D2 production in mouse mast cells. (2008) (5)
Post-transcriptional regulation of LTC4 synthase activity by retinoic acid in rat basophilic leukemia cells. (1997) (5)
Bioactive Lipid Mediators (2015) (5)
Characterization of cytosolic phospholipase A2 in rat mastocytoma RBL-2H3. (1994) (5)
Characteristics and possible functions of mast cell phospholipases A2. (1992) (5)
Cytosolic phospholipase A2 alpha interacts with microtubules. (2002) (5)
BETA-(N-ACETYLGLUCOSAMINE)-N-GLYCOSIDASE: AN ENZYME WHICH CATALYZES THE HYDROLYSIS OF 1-BETA-ASPARTYL-2-ACETAMIDO-1,2-DIDEOXY-D-GLUCOSYLAMINE. (1965) (4)
Critical amino acids responsible for conferring calcium channel characteristics are located on the surface and aroundβ-turn potentials of channel proteins (1995) (4)
Purification, Properties and Recognition Sequence of Site-specific Restriction Endonuclease from Gluconobacter cerinus IFO 3285 (1985) (4)
Type IIA secretory PLA2-mediated delayed PGE2 biosynthesis is regulated by the products of the cytosolic PLA2. (2002) (4)
In vivo localization of secretory type V phospholipase A2 (sPLA2-V) in human salivary glands under normal and pathological conditions (2009) (4)
Segregated Functions of Two Cytosolic Phospholipase A2 Isoforms (cPLA2α and cPLA2ε) in Lipid Mediator Generation. (2022) (4)
Transgenic Expression of Group V, but Not Group X, Secreted Phospholipase A 2 in Mice Leads to Neonatal Lethality (2006) (4)
Regulatory Roles of Phospholipase A2 Enzymes and Bioactive Lipids in Mast Cell Biology (2022) (4)
Lack of Phospholipase A 2 Receptor Increases Susceptibility to Cardiac Rupture After Myocardial Infarction (2014) (4)
Lipid Networks in Mast Cell Biology (2011) (4)
[Toxicity profile of silodosin (KMD-3213)]. (2006) (3)
Lysophosphatidylserine enhances exogenous type II phospholipase A2-induced activation of rat serosal mast cells. (1996) (3)
Mast Cell-Specific Deletion of Group III Secreted Phospholipase A2 Impairs Mast Cell Maturation and Functions (2021) (3)
Preparation of antibodies to phospholipases A2. (1991) (3)
Characterization and molecular cloning of mouse type II phospholipase A2. (1997) (3)
Hepatic phosphatidylcholine catabolism driven by PNPLA7 and PNPLA8 supplies endogenous choline to replenish the methionine cycle with methyl groups. (2023) (3)
Resonant Recognition Model of Neuropeptide Y Family: Hot Spot Amino Acid Distribution in the Sequences (2000) (3)
Positive and negative roles of lipids in mast cells and allergic responses. (2021) (3)
Immunological Regulation by Bioactive Lipids. (2017) (3)
Characterization of restriction endonuclease BdiSI, an isoschizomer of SfeI, from Bacteroides distasonis strain S-7. (1991) (2)
Physiological Roles of Group X-secreted Phospholipase A 2 in Reproduction, Gastrointestinal Phospholipid Digestion, and (2011) (2)
Comparison of recombinant types IIA, V and IIC phospholipase A2S, the three related mammalian secretory phospholipase A2 isozymes. (1999) (2)
Another way for sPLA2 to meet with cells (2003) (2)
Phospholipase A2 in Inflamed Tissues and Inflammatory Exudates (1997) (2)
A New Restriction Endonuclease fromAcetobacter pasteurianus(ApaLl) (1985) (2)
Analysis of Two Major Intracellular Phospholipase A 2 s in Mast Cells Reveals Crucial Contribution of cPLA 2 α , not iPLA 2 β , to Lipid Mobilization in Proximal Mast Cells and Distal Fibroblasts (2011) (2)
Formation of N-acyl-phosphatidylethanolamines by cytosolic phospholipase A2ε in an ex vivo murine model of brain ischemia. (2022) (2)
Purification, properties and recognition sequence and cleavage site determinations of restriction endonuclease from Acetobacter pasteurianus IFO 13753 (ApaLI). (1990) (2)
Abnormal male reproduction and embryonic development induced by downregulation of a phospholipid fatty acid-introducing enzyme Lpgat1 in zebrafish (2022) (2)
Author Correction: Sirt1 negatively regulates FcεRI-mediated mast cell activation through AMPK- and PTP1B-dependent processes (2020) (2)
Group V Secretory Phospholipase A2 Regulates Endocytosis of Acetylated LDL by Transcriptional Activation of PGK1 in RAW264.7 Macrophage Cell Line (2021) (1)
Corrigendum to “Anti-inflammatory activity of hexane extracts from bones and internal organs of Anguilla japonica suppresses cyclooxygenase-2-dependent prostaglandin D2 generation in mast cells and anaphylaxis in mice” [Food Chem. Toxicol. 57 (2013) 307–313] (2014) (1)
Special issue Phospholipases A2 and lipid mediators (2010) (1)
Effect of feeding fish oil on uterine secretion of PGF 2 α , milk composition , and metabolic status of peri-parturient Holstein cows (2002) (1)
[Functional coupling between phospholipase A2 and cyclooxygenase]. (1999) (1)
Prostaglandin E2 synthase (2000) (1)
The Lysophospholipase PNPLA7 Controls Hepatic Choline and Methionine Metabolism (2023) (1)
Malabaricone C derived from nutmeg inhibits arachidonate 5-lipoxygenase activity and ameliorates psoriasis-like skin inflammation in mice. (2022) (1)
Studies on a Mechanism by Which Cytosolic Phospholipase A 2 Regulates the Expression and Function of Type IIA Secretory (2000) (1)
The restriction endonuclease GceinI of Gluconobacter cerinus IFO 3260, an isoschizomer of BamHI, has a monomeric structure. (1990) (1)
[101] β-Aspartyl-N-acetylglucosaminadase from epididymis (1966) (1)
Renoprotective Effect of the L/N-Type Calcium Channel Antagonist Cilnidipine on Puromycin Aminonucleoside-Induced Nephrosis in Rats (2009) (1)
This information is current as-Deficient Mice Ndrg 1 Responses in Degranulation and Attenuated Allergic Impaired Mast Cell Maturation and (2007) (1)
A new restriction endonuclease from Bacteroides distasonis (BdiI). (1990) (1)
[Phospholipase A2 and inflammation]. (1996) (1)
Regulation of prostaglandin, leukotriene, and platelet-activating factor metabolism in mast cells. (1999) (1)
[Phospholipase A2]. (1999) (0)
324 Type-II PLA2 supplies arachidonic acid to PGHS-2 in the delayed phase of PGD2 generation by mouse mast cells (1996) (0)
Changes in kinetic properties of cytosolic phospholipase A2 in activated rat neutrophils. (1997) (0)
Lysophosphatidic acids regulates mast cell maturation (2015) (0)
Modulation of immunity by the secreted phospholipase A2 family. (2023) (0)
Aberrant activation of skin-specific CAPN12 is involved in development of psoriasis (2017) (0)
Lipid profiling reveals the presence of unique lipid mediators in human milk from healthy and mastitic subjects. (2022) (0)
Physiological roles of secreted phospholipase A2 enzymes (2008) (0)
Phospholipase A2 in skin biology: new insights from gene-manipulated mice and lipidomics (2018) (0)
[LIPIDS IN ALLERGIC DISEASES]. (2020) (0)
Lipid-Orchestrated Acceleration of Epstein-Barr Virus-Induced B-Cell Lymphoma Via the Secreted Phospholipase A 2-Mediated Modification of Exosomes (2021) (0)
Skeletal muscle weakness and atrophy in membrane-associated calcium-independent phospholipase A2 (iPLA2γ)-deficient mice (2009) (0)
Effect of red rice proanthocyanidin on prostaglandin E 2 production (2017) (0)
Purification, Properties and Recognition Sequence and Cleavage Site Determinations of Restriction Endonuclease from Acetobacter pasteurianus IFO 13753 (ApaIA)f (2006) (0)
Functional linkage between secretory phospholipase A2 (sPLA2) and membrane-bound prostaglandin E2 synthase (mPGES) (2002) (0)
The phospholipase A2 superfamily as a central hub of bioactive lipids and beyond. (2023) (0)
Blue light alters cellular lipidome—Light-induced lipidomic changes can be modulated by optogenetically engineered cPLA2α (2022) (0)
Age-related dysregulation in the lipidome compromises the immune response to the severe acute respiratory coronavirus (VIR5P.1140) (2015) (0)
β-(N-Acetylglucosamine)-N-glycosidase: an Enzyme Which Catalyzes the Hydrolysis of 1-β-Aspartyl-2-acetamido-1,2-dideoxy-d-glucosylamine (1965) (0)
Mini Review Inflammation and Regeneration (2009) (0)
Direct methane production from baiomass by co-culture of anaerobic fungus, Neocallimastix frontalis and methanogens. (1999) (0)
[Arachidonate metabolism in mast cells]. (1997) (0)
Analysis of viral replication regulating factors in bovine leukemia virus using chemical biology approach (2019) (0)
Type IIA sPLA2-mediated delayed pge2 biosynthesis is regulated by the product(s) of the cPLA2 and 12-lipoxygenase pathway (1999) (0)
The Restriction Endonuclease GceinI of Gluconobacter cerinus IFO 3260, an Isoschizomer of BamHI, Has a Monomeric Structure(Microbiology & Fermentation Industry) (1990) (0)
Simulation of ATP Hydrolysis with Table Form (2011) (0)
Functional coupling among phospholipase A2s, cyclooxygenases, and terminal prostaglandin synthases in immediate and delyed prostanoid biosynthetic pathways (1999) (0)
Author Correction: Sirt1 negatively regulates FcεRI-mediated mast cell activation through AMPK- and PTP1B-dependent processes (2020) (0)
Sirt1 negatively regulates FcεRI-mediated mast cell activation through AMPK- and PTP1B-dependent processes (2017) (0)
The role of oxidized phaspholipid-derived lipid mediators in IgE-mediated mast cell activation (2016) (0)
[New insights into the roles of secreted phospholipase A2s in immunity]. (2014) (0)
Influences of Lactobacillus and Cellobiose on the Composition and Metabolic Activity of Fecal Microbiota in Dogs given Boiled Chicken Head and Cow Milk (2008) (0)
Phospholipase A2 as a Potential Drug Target for Airway Disorders (2011) (0)
Matrix Metalloproteinase-2 Negatively Regulates Cardiac Secreted Phospholipase A 2 to Modulate In fl ammation and Fever (2015) (0)
Strain differences in phenobarbital metabolism between SD and Wistar rats(Proceedings of the 32nd Annual Meeting) (2005) (0)
Purification and characterization of cow milk lipocalin-type prostaglandin D synthase as a potential biomarker of bovine mastitis (2017) (0)
2 Phospholipase A and Function of Type IIA Secretory Regulates the Expression 2 Phospholipase A Studies on a Mechanism by Which Cytosolic (2000) (0)
Lipid mediators in immune reactions (WS-106) Chairpersons: Takehiko Yokomizo, Satoshi Ishii (2010) (0)
Prostaglandin D in the Regulation of Degranulation and 2 II Subfamily of Secretory Phospholipases A Granule-Associated Heparin-Binding Group Redundant and Segregated Functions of (2000) (0)
Organism-Wide Analysis of Sepsis Reveals Mechanisms of Systemic Inflammation (2023) (0)
Biosynthesis in Rat Peritoneal Macrophages Synthases in Different Phases of Prostanoid Cyclooxygenases, and Terminal Prostanoid ,2 Segregated Coupling of Phospholipases A (1998) (0)
secreted phospholipase A 2 transgenic mice spontaneously develop inflammation (2009) (0)
Group III phospholipase A2 promotes colitis and colorectal cancer (2017) (0)
Characterization of restriction endonuclease CbiI, an isoschizomer of AsuII, from Clostridium bifermentans strain B-4. (1991) (0)
A New Restriction Endonuclease fromBacteroides distasonis(BdiI) (1990) (0)
An anti-sulfatide antibody O4 immunoprecipitates sulfatide rafts including Fyn, Lyn and the G protein α subunit in rat primary immature oligodendrocytes (2013) (0)
The Roles of sPLA2s in Skin Homeostasis and Disease (2023) (0)
COMPARISON OF RECOMBINANT TYPES IIA, V AND IIC PHOSPHOLIPASE A2S, THE THREE RELATED MAMMALIAN SECRETORY PHOSPHOLIPASE A2ISOZYMES INTRODUCTION (0)
Hypercholesterolemic Dysregulation of Calpain in Lymphatic Endothelial Cells Interferes With Regulatory T-Cell Stability and Trafficking (2022) (0)
[Phospholipase A2]. (2020) (0)
PAF & Arachidonic Acid Cascade (2014) (0)
Metabolic regulation by secreted phospholipase A2 (2016) (0)
Identification of sPLA2 that promotes adipocyte beiging. (2017) (0)

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