Makoto Murakami
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Computer Science
Makoto Murakami's Degrees
- PhD Computer Science University of Tokyo
- Masters Computer Science University of Tokyo
- Bachelors Computer Science University of Tokyo
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(Suggest an Edit or Addition)Makoto Murakami's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Regulation of Prostaglandin E2 Biosynthesis by Inducible Membrane-associated Prostaglandin E2 Synthase That Acts in Concert with Cyclooxygenase-2* (2000) (985)
- Phospholipase A2 enzymes. (2002) (726)
- Molecular Identification of Cytosolic Prostaglandin E2 Synthase That Is Functionally Coupled with Cyclooxygenase-1 in Immediate Prostaglandin E2Biosynthesis* (2000) (706)
- Recent progress in phospholipase A₂ research: from cells to animals to humans. (2011) (438)
- Regulatory functions of phospholipase A2. (1997) (406)
- The Lipid Mediator Protectin D1 Inhibits Influenza Virus Replication and Improves Severe Influenza (2013) (395)
- The Functions of Five Distinct Mammalian Phospholipase A2s in Regulating Arachidonic Acid Release (1998) (384)
- Functional Coupling Between Various Phospholipase A2s and Cyclooxygenases in Immediate and Delayed Prostanoid Biosynthetic Pathways* (1999) (361)
- Cellular Prostaglandin E2 Production by Membrane-bound Prostaglandin E Synthase-2 via Both Cyclooxygenases-1 and -2* (2003) (354)
- Mammalian non-pancreatic phospholipases A2. (1993) (344)
- Recent advances in molecular biology and physiology of the prostaglandin E2-biosynthetic pathway. (2004) (322)
- Reduced Pain Hypersensitivity and Inflammation in Mice Lacking Microsomal Prostaglandin E Synthase-1* (2004) (297)
- Prostaglandin E synthase. (2002) (265)
- Prostaglandin endoperoxide synthase-1 and -2 couple to different transmembrane stimuli to generate prostaglandin D2 in mouse bone marrow-derived mast cells. (1994) (236)
- Fas-induced Arachidonic Acid Release Is Mediated by Ca2+-independent Phospholipase A2 but Not Cytosolic Phospholipase A2, Which Undergoes Proteolytic Inactivation* (1998) (232)
- Biosynthesis of anandamide and N-palmitoylethanolamine by sequential actions of phospholipase A2 and lysophospholipase D. (2004) (228)
- Exogenously Added Human Group X Secreted Phospholipase A2 but Not the Group IB, IIA, and V Enzymes Efficiently Release Arachidonic Acid from Adherent Mammalian Cells* (2000) (216)
- Coupling between Cyclooxygenase, Terminal Prostanoid Synthase, and Phospholipase A2 * (2001) (205)
- Secretory phospholipase A2. (2004) (198)
- Molecular nature of phospholipases A2 involved in prostaglandin I2 synthesis in human umbilical vein endothelial cells. Possible participation of cytosolic and extracellular type II phospholipases A2. (1993) (197)
- Cytosolic Phospholipase A2 Is Required for Cytokine-induced Expression of Type IIA Secretory Phospholipase A2 That Mediates Optimal Cyclooxygenase-2-dependent Delayed Prostaglandin E2 Generation in Rat 3Y1 Fibroblasts* (1998) (196)
- Potential Role of Microsomal Prostaglandin E Synthase-1 in Tumorigenesis* (2003) (195)
- Secreted phospholipase A2 revisited. (2011) (195)
- Segregated coupling of phospholipases A2, cyclooxygenases, and terminal prostanoid synthases in different phases of prostanoid biosynthesis in rat peritoneal macrophages. (1998) (194)
- Prostaglandin E synthase, a terminal enzyme for prostaglandin E2 biosynthesis. (2005) (185)
- Distinct Arachidonate-releasing Functions of Mammalian Secreted Phospholipase A2s in Human Embryonic Kidney 293 and Rat Mastocytoma RBL-2H3 Cells through Heparan Sulfate Shuttling and External Plasma Membrane Mechanisms* (2001) (180)
- Phospholipase A2. (2002) (179)
- Distinct Roles of Two Intracellular Phospholipase A2s in Fatty Acid Release in the Cell Death Pathway (2000) (172)
- Functional Association of Type IIA Secretory Phospholipase A2 with the Glycosylphosphatidylinositol-anchored Heparan Sulfate Proteoglycan in the Cyclooxygenase-2-mediated Delayed Prostanoid-biosynthetic Pathway* (1999) (172)
- Concordant induction of prostaglandin E2 synthase with cyclooxygenase-2 leads to preferred production of prostaglandin E2 over thromboxane and prostaglandin D2 in lipopolysaccharide-stimulated rat peritoneal macrophages. (1997) (166)
- A new era of secreted phospholipase A2 (2015) (165)
- Different functional aspects of the group II subfamily (Types IIA and V) and type X secretory phospholipase A(2)s in regulating arachidonic acid release and prostaglandin generation. Implications of cyclooxygenase-2 induction and phospholipid scramblase-mediated cellular membrane perturbation. (1999) (163)
- Transcriptional Regulation of the Membrane-associated Prostaglandin E2 Synthase Gene (2002) (156)
- Diversity and regulatory functions of mammalian secretory phospholipase A2s. (2001) (150)
- c-Kit Ligand Mediates Increased Expression of Cytosolic Phospholipase A, Prostaglandin Endoperoxide Synthase-1, and Hematopoietic Prostaglandin D Synthase and Increased IgE-dependent Prostaglandin D Generation in Immature Mouse Mast Cells (*) (1995) (150)
- Prostaglandin E synthase: a novel drug target for inflammation and cancer. (2006) (142)
- A new class of COX-2 inhibitor, rutaecarpine from Evodia rutaecarpa (1999) (140)
- Prostaglandin E synthases: Understanding their pathophysiological roles through mouse genetic models. (2010) (138)
- Type II Secretory Phospholipase A2 Associated with Cell Surfaces via C-terminal Heparin-binding Lysine Residues Augments Stimulus-initiated Delayed Prostaglandin Generation* (1996) (137)
- Mast cells mediate neutrophil recruitment and vascular leakage through the NLRP3 inflammasome in histamine-independent urticaria (2009) (133)
- Emerging roles of secreted phospholipase A2 enzymes: Lessons from transgenic and knockout mice. (2010) (132)
- Lipid mediators in life science. (2011) (130)
- Activation of Cytosolic Phospholipase A2 by Platelet-derived Growth Factor Is Essential for Cyclooxygenase-2-dependent Prostaglandin E2 Synthesis in Mouse Osteoblasts Cultured with Interleukin-1* (1997) (129)
- Coupling between cyclooxygenases and terminal prostanoid synthases. (2005) (127)
- Prostaglandin E2 Amplifies Cytosolic Phospholipase A2- and Cyclooxygenase-2-dependent Delayed Prostaglandin E2 Generation in Mouse Osteoblastic Cells (1997) (127)
- Small RNA transcriptomes of two types of exosomes in human whole saliva determined by next generation sequencing. (2013) (127)
- Analyses of Group III Secreted Phospholipase A2 Transgenic Mice Reveal Potential Participation of This Enzyme in Plasma Lipoprotein Modification, Macrophage Foam Cell Formation, and Atherosclerosis* (2008) (121)
- Use of nisin for inhibition of Alicyclobacillus acidoterrestris in acidic drinks. (2000) (115)
- Regulatory Functions of Phospholipase A2. (2017) (114)
- Prostaglandin E2–EP3 Signaling Induces Inflammatory Swelling by Mast Cell Activation (2014) (113)
- Characterization of a haemolytic factor from Candida albicans. (1999) (113)
- Lysophosphatidylcholine acyltransferase 1 altered phospholipid composition and regulated hepatoma progression. (2013) (112)
- The immediate phase of c-kit ligand stimulation of mouse bone marrow- derived mast cells elicits rapid leukotriene C4 generation through posttranslational activation of cytosolic phospholipase A2 and 5- lipoxygenase (1995) (111)
- The perturbed membrane of cells undergoing apoptosis is susceptible to type II secretory phospholipase A2 to liberate arachidonic acid. (1997) (108)
- Mast cell maturation is driven via a group III phospholipase A2-prostaglandin D2–DP1 receptor paracrine axis (2013) (102)
- Lymphoid tissue phospholipase A2 group IID resolves contact hypersensitivity by driving antiinflammatory lipid mediators (2013) (101)
- Critical role of phospholipase A2 group IID in age-related susceptibility to severe acute respiratory syndrome–CoV infection (2015) (101)
- Release of secretory phospholipase A2 from rat neuronal cells and its possible function in the regulation of catecholamine secretion. (1996) (101)
- Group III secreted phospholipase A2 regulates epididymal sperm maturation and fertility in mice. (2010) (98)
- A Heparin-sensitive Phospholipase A2 and Prostaglandin Endoperoxide Synthase-2 Are Functionally Linked in the Delayed Phase of Prostaglandin D2 Generation in Mouse Bone Marrow-derived Mast Cells* (1996) (97)
- Cellular components that functionally interact with signaling phospholipase A(2)s. (2000) (97)
- PNPLA1 has a crucial role in skin barrier function by directing acylceramide biosynthesis (2017) (96)
- Transgenic Expression of Group V, but Not Group X, Secreted Phospholipase A2 in Mice Leads to Neonatal Lethality because of Lung Dysfunction* (2006) (95)
- Regulation of type V phospholipase A2 expression and function by proinflammatory stimuli. (1999) (94)
- Triggering of degranulation in mast cells by exogenous type II phospholipase A2. (1993) (93)
- RalA Functions as an Indispensable Signal Mediator for the Nutrient-sensing System* (2008) (92)
- Identification of a Cellular Protein That Functionally Interacts with the C2 Domain of Cytosolic Phospholipase A2α* (2000) (92)
- IgE-dependent activation of cytokine-primed mouse cultured mast cells induces a delayed phase of prostaglandin D2 generation via prostaglandin endoperoxide synthase-2. (1995) (92)
- The adipocyte-inducible secreted phospholipases PLA2G5 and PLA2G2E play distinct roles in obesity. (2014) (90)
- Eicosanoid generation from antigen‐primed mast cells by extracellular mammalian 14‐kDa group II phospholipase A2 (1991) (89)
- Induction of cyclooxygenase-2 by secretory phospholipases A2 in nerve growth factor-stimulated rat serosal mast cells is facilitated by interaction with fibroblasts and mediated by a mechanism independent of their enzymatic functions. (1998) (89)
- Release of 14-kDa group-II phospholipase A2 from activated mast cells and its possible involvement in the regulation of the degranulation process. (1992) (87)
- Emodin, a naturally occurring anthraquinone derivative, suppresses IgE-mediated anaphylactic reaction and mast cell activation. (2011) (85)
- Purification of rabbit platelet secretory phospholipase A2 and its characteristics. (1989) (85)
- Expression of secretory phospholipase A2 enzymes in lungs of humans with pneumonia and their potential prostaglandin-synthetic function in human lung-derived cells. (2005) (85)
- Emerging roles of secreted phospholipase A(2) enzymes: an update. (2013) (80)
- Regulation of cytosolic prostaglandin E synthase by phosphorylation. (2004) (80)
- New phospholipase A2 isozymes with a potential role in atherosclerosis (2003) (79)
- Regulation of cytosolic prostaglandin E2 synthase by 90-kDa heat shock protein. (2003) (79)
- Mouse bone marrow-derived mast cells undergo exocytosis, prostanoid generation, and cytokine expression in response to G protein-activating polybasic compounds after coculture with fibroblasts in the presence of c-kit ligand. (1997) (77)
- Thermal resistance ofAlicyclobacillus acidoterrestrisspores in different buffers and pH (1998) (77)
- Cellular Distribution, Post-translational Modification, and Tumorigenic Potential of Human Group III Secreted Phospholipase A2* (2005) (76)
- Cellular Arachidonate-releasing Function of Novel Classes of Secretory Phospholipase A2s (Groups III and XII)* (2003) (76)
- Diverse cellular localizations of secretory phospholipase A2 enzymes in several human tissues. (2005) (75)
- Critical role of PICT-1, a tumor suppressor candidate, in phosphatidylinositol 3,4,5-trisphosphate signals and tumorigenic transformation. (2006) (75)
- Expression of secretory phospholipase A2s in human atherosclerosis development. (2008) (74)
- Induction of distinct sets of secretory phospholipase A(2) in rodents during inflammation. (2003) (72)
- Detection of three distinct phospholipases A2 in cultured mast cells. (1992) (70)
- Microsomal prostaglandin E synthase-1 in both cancer cells and hosts contributes to tumour growth, invasion and metastasis (2009) (69)
- m-Calpain Induction in Vascular Endothelial Cells on Human and Mouse Atheromas and Its Roles in VE-Cadherin Disorganization and Atherosclerosis (2011) (69)
- Neuronal Expression and Neuritogenic Action of Group X Secreted Phospholipase A2* (2005) (69)
- Emerging roles of secreted phospholipase A2 enzymes: the 3rd edition. (2014) (69)
- Cellular Arachidonate-releasing Function and Inflammation-associated Expression of Group IIF Secretory Phospholipase A2 * (2002) (68)
- Various secretory phospholipase A2 enzymes are expressed in rheumatoid arthritis and augment prostaglandin production in cultured synovial cells (2005) (68)
- Secretory phospholipases A2. (1995) (68)
- Studies on a Mechanism by Which Cytosolic Phospholipase A2 Regulates the Expression and Function of Type IIA Secretory Phospholipase A21 (2000) (68)
- Group X phospholipase A2 is released during sperm acrosome reaction and controls fertility outcome in mice. (2010) (66)
- Participation in cellular prostaglandin synthesis of type-II phospholipase A2 secreted and anchored on cell-surface heparan sulfate proteoglycan. (1993) (65)
- Updating Phospholipase A2 Biology (2020) (64)
- Group VIB Ca2+-independent Phospholipase A2γ Promotes Cellular Membrane Hydrolysis and Prostaglandin Production in a Manner Distinct from Other Intracellular Phospholipases A2* (2005) (64)
- Microsomal prostaglandin E synthase-1 is involved in multiple steps of colon carcinogenesis (2012) (63)
- Human group III secreted phospholipase A2 promotes neuronal outgrowth and survival. (2008) (63)
- Redundant and Segregated Functions of Granule-Associated Heparin-Binding Group II Subfamily of Secretory Phospholipases A2 in the Regulation of Degranulation and Prostaglandin D2 Synthesis in Mast Cells1 (2000) (62)
- Group X Secreted Phospholipase A2 Limits the Development of Atherosclerosis in LDL Receptor–Null Mice (2013) (61)
- The role of group IIF-secreted phospholipase A2 in epidermal homeostasis and hyperplasia (2015) (58)
- Possible role of mammalian secretory group II phospholipase A2 in T-lymphocyte activation: implication in propagation of inflammatory reaction. (1993) (57)
- Exacerbation of rat adjuvant arthritis by intradermal injection of purified mammalian 14‐kDa group II phospholipase A2 (1990) (55)
- Arachidonate release and eicosanoid generation by group IIE phospholipase A(2). (2002) (54)
- Role of cytosolic phospholipase A2 in the production of lipid mediators and histamine release in mouse bone-marrow-derived mast cells. (2000) (54)
- Group X Secreted Phospholipase A2 Releases ω3 Polyunsaturated Fatty Acids, Suppresses Colitis, and Promotes Sperm Fertility* (2016) (54)
- Group V and X secretory phospholipase A2 prevents adenoviral infection in mammalian cells. (2006) (53)
- The Roles of the Secreted Phospholipase A2 Gene Family in Immunology (2016) (52)
- Stabilization of mast cells by heme oxygenase-1: an anti-inflammatory role. (2002) (51)
- Identification of NDRG1 as an early inducible gene during in vitro maturation of cultured mast cells. (2003) (51)
- Induction of cyclooxygenase-2 causes an enhancement of writhing response in mice. (1998) (51)
- Parkinson’s disease-associated iPLA2-VIA/PLA2G6 regulates neuronal functions and α-synuclein stability through membrane remodeling (2019) (50)
- Immunochemical detection of 'platelet type' phospholipase A2 in the rat. (1990) (50)
- PGD2 induces eotaxin-3 via PPARγ from sebocytes: a possible pathogenesis of eosinophilic pustular folliculitis. (2012) (50)
- Strain differences in hepatic cytochrome P450 1A and 3A expression between Sprague-Dawley and Wistar rats. (2008) (50)
- Efficient production of cellulolytic and xylanolytic enzymes by the rumen anaerobic fungus, Neocallimastix frontalis, in a repeated batch culture. (2001) (48)
- Group III secreted phospholipase A2 transgenic mice spontaneously develop inflammation (2009) (48)
- Lipoquality control by phospholipase A2 enzymes (2017) (47)
- Phosphatidylethanolamine dynamics are required for osteoclast fusion (2017) (45)
- Regulation of cyclooxygenase-2 and endogenous cytokine expression by bacterial lipopolysaccharide that acts in synergy with c-kit ligand and Fc epsilon receptor I crosslinking in cultured mast cells. (1998) (45)
- Localization of various secretory phospholipase A2 enzymes in male reproductive organs. (2004) (45)
- Physiological Roles of Group X-secreted Phospholipase A2 in Reproduction, Gastrointestinal Phospholipid Digestion, and Neuronal Function* (2011) (44)
- Dual Roles of Group IID Phospholipase A2 in Inflammation and Cancer* (2016) (44)
- Deficiency of Phospholipase A2 Receptor Exacerbates Ovalbumin-Induced Lung Inflammation (2013) (44)
- Impaired Mast Cell Maturation and Degranulation and Attenuated Allergic Responses in Ndrg1-Deficient Mice1 (2007) (43)
- A Novel Role of Group VIB Calcium-independent Phospholipase A2 (iPLA2γ) in the Inducible Expression of Group IIA Secretory PLA2 in Rat Fibroblastic Cells* (2007) (42)
- Roles of endogenous prostaglandins and cyclooxygenase izoenzymes in mucosal defense of inflamed rat stomach. (2004) (41)
- Mitochondrial dysfunction and reduced prostaglandin synthesis in skeletal muscle of Group VIB Ca2+-independent phospholipase A2γ-deficient mice[S] (2010) (40)
- Establishment of the culture model system that reflects the process of terminal differentiation of connective tissue‐type mast cells (2008) (39)
- Association of microsomal prostaglandin E synthase 1 deficiency with impaired fracture healing, but not with bone loss or osteoarthritis, in mouse models of skeletal disorders. (2008) (39)
- N-myc downregulated gene 1 is a phosphorylated protein in mast cells. (2004) (39)
- Direct conversion of cellulose to methane by anaerobic fungus Neocallimastix frontalis and defined methanogens (2000) (39)
- Metabolic regulation by secreted phospholipase A2 (2016) (39)
- Interleukin 4 suppresses c-kit ligand-induced expression of cytosolic phospholipase A2 and prostaglandin endoperoxide synthase 2 and their roles in separate pathways of eicosanoid synthesis in mouse bone marrow-derived mast cells. (1995) (38)
- Papyriflavonol A from Broussonetia papyrifera inhibits the passive cutaneous anaphylaxis reaction and has a secretory phospholipase A2-inhibitory activity. (2003) (38)
- Omega-3 fatty acid epoxides are autocrine mediators that control the magnitude of IgE-mediated mast cell activation (2017) (38)
- Neuropeptide Y content in the hypothalamic paraventricular nucleus responds to fasting and refeeding in broiler chickens. (2005) (38)
- Cyclooxygenase-2-dependent delayed prostaglandin D2 generation is initiated by nerve growth factor in rat peritoneal mast cells: its augmentation by extracellular type II secretory phospholipase A2. (1997) (38)
- Eicosanoid signalling blockade protects middle-aged mice from severe COVID-19 (2022) (37)
- Contribution of membrane‐associated prostaglandin E2 synthase to bone resorption (2003) (37)
- Cross-linking of the high-affinity IgE receptor induces the expression of cyclo-oxygenase 2 and attendant prostaglandin generation requiring interleukin 10 and interleukin 1 beta in mouse cultured mast cells. (1996) (37)
- Arachidonate release and prostaglandin production by group IVC phospholipase A2 (cytosolic phospholipase A2gamma). (2003) (37)
- Dual regulation of cytosolic phospholipase A2 in mast cells after cross-linking of FC epsilon-receptor. (1994) (37)
- Activated Mast Cells Release Extracellular Type Platelet-activating Factor Acetylhydrolase That Contributes to Autocrine Inactivation of Platelet-activating Factor* (1997) (37)
- Monoclonal antibodies against rat platelet phospholipase A2. (1988) (36)
- The role of PNPLA1 in ω-O-acylceramide synthesis and skin barrier function. (2019) (36)
- Novel functions of phospholipase A2s: Overview. (2019) (36)
- CHARACTERIZATION OF CYTOCHROME P450 EXPRESSION IN MURINE EMBRYONIC STEM CELL-DERIVED HEPATIC TISSUE SYSTEM (2006) (35)
- Oligo‐astheno‐teratozoospermia in mice lacking ORP4, a sterol‐binding protein in the OSBP‐related protein family (2014) (35)
- Group II phospholipase A2 inhibitors suppressed lysophosphatidylserine-dependent degranulation of rat peritoneal mast cells. (1991) (35)
- In vivo release and clearance of rat platelet phospholipase A2. (1989) (34)
- Autotaxin–lysophosphatidic acid–LPA 3 signaling at the embryo‐epithelial boundary controls decidualization pathways (2017) (33)
- Calpastatin counteracts pathological angiogenesis by inhibiting suppressor of cytokine signaling 3 degradation in vascular endothelial cells. (2015) (33)
- Matrix Metalloproteinase‐2 Negatively Regulates Cardiac Secreted Phospholipase A2 to Modulate Inflammation and Fever (2015) (32)
- Human group III phospholipase A2 suppresses adenovirus infection into host cells. Evidence that group III, V and X phospholipase A2s act on distinct cellular phospholipid molecular species. (2007) (32)
- Association of N-myc downregulated gene 1 with heat-shock cognate protein 70 in mast cells. (2004) (32)
- AMP-activated protein kinase negatively regulates FcεRI-mediated mast cell signaling and anaphylaxis in mice. (2013) (32)
- Diverse functional coupling of prostanoid biosynthetic enzymes in various cell types. (1999) (31)
- Secreted phospholipase A2, lipoprotein hydrolysis, and atherosclerosis: integration with lipidomics (2011) (30)
- Expression of type V secretory phospholipase A2 in myocardial remodelling after infarction (2005) (30)
- Secreted Phospholipase PLA2G2D Contributes to Metabolic Health by Mobilizing ω3 Polyunsaturated Fatty Acids in WAT. (2020) (29)
- Polyunsaturated fatty acids potentiate interleukin‐1‐stimulated arachidonic acid release by cells overexpressing type IIA secretory phospholipase A2 (1999) (29)
- Secreted phospholipase A2 and mast cells. (2015) (29)
- Lack of Phospholipase A2 Receptor Increases Susceptibility to Cardiac Rupture After Myocardial Infarction (2014) (29)
- Immunochemical detection of arachidonoyl-preferential phospholipase A2. (1992) (28)
- Hot topics in phospholipase A2 field. (2004) (28)
- Group IID heparin-binding secretory phospholipase A(2) is expressed in human colon carcinoma cells and human mast cells and up-regulated in mouse inflammatory tissues. (2002) (27)
- Agonist stimulation of B1 and B2 kinin receptors causes activation of the MAP kinase signaling pathway, resulting in the translocation of AP‐1 in HEK 293 cells (1998) (26)
- Unique Membrane Interaction Mode of Group IIF Phospholipase A2* (2006) (26)
- Activation of inflammation and resolution pathways of lipid mediators in synovial fluid from patients with severe rheumatoid arthritis compared with severe osteoarthritis (2020) (26)
- Hair Follicular Expression and Function of Group X Secreted Phospholipase A2 in Mouse Skin* (2011) (26)
- NecroX‐5 suppresses IgE/Ag‐stimulated anaphylaxis and mast cell activation by regulating the SHP‐1‐Syk signaling module (2016) (25)
- ERK1/2 antagonize AMPK-dependent regulation of FcεRI-mediated mast cell activation and anaphylaxis. (2014) (25)
- Functional coupling between various phospholipase A_2s and cyclooxygenases in immediate and delayed prostanoid biosynthetic pathway (2001) (25)
- Perinuclear localization of cytosolic phospholipase A2α is important but not obligatory for coupling with cyclooxygenases (2003) (25)
- Characteristics and pathophysiological roles of extracellular phospholipase A2 in inflamed sites. (1989) (25)
- Secreted Phospholipase A2 Specificity on Natural Membrane Phospholipids. (2017) (24)
- Group III phospholipase A2 promotes colitis and colorectal cancer (2017) (24)
- Change in prostaglandin E synthases (PGESs) in microsomal PGES-1 knockout mice in a preterm delivery model. (2005) (24)
- Eicosanoid signaling as a therapeutic target in middle-aged mice with severe COVID-19 (2021) (23)
- Group VIB Calcium-Independent Phospholipase A2 (iPLA2γ) Regulates Platelet Activation, Hemostasis and Thrombosis in Mice (2014) (23)
- Distribution of type V secretory phospholipase A2 expression in human hepatocytes damaged by liver disease (2004) (23)
- Sirt1 negatively regulates FcεRI-mediated mast cell activation through AMPK- and PTP1B-dependent processes (2017) (23)
- Internalization and degradation of type IIA phospholipase A(2) in mast cells. (2000) (23)
- Leukotriene B4 receptor type 2 protects against pneumolysin-dependent acute lung injury (2016) (22)
- Phospholipase D is involved in cytosolic phospholipase A2‐dependent selective release of arachidonic acid by fMLP‐stimulated rat neutrophils (1996) (22)
- Search of Factors That Intermediate Cytokine-induced Group IIA Phospholipase A2 Expression through the Cytosolic Phospholipase A2- and 12/15-Lipoxygenase-dependent Pathway* (2005) (21)
- Age-dependent appearance of NK1.1+ T cells in the livers of beta2-microglobulin knockout and SJL mice. (1998) (21)
- Group IID, IIE, IIF and III secreted phospholipase A2s☆ (2018) (21)
- Analysis of Two Major Intracellular Phospholipases A2 (PLA2) in Mast Cells Reveals Crucial Contribution of Cytosolic PLA2α, Not Ca2+-independent PLA2β, to Lipid Mobilization in Proximal Mast Cells and Distal Fibroblasts* (2011) (21)
- Critical role for cytosolic group IVA phospholipase A2 in early adipocyte differentiation and obesity. (2016) (21)
- Tanshinone IIA suppresses Fc&egr;RI‐mediated mast cell signaling and anaphylaxis by activation of the Sirt1/LKB1/AMPK pathway (2018) (21)
- Distribution of smooth muscle cells and macrophages expressing scavenger receptor BI/II in atherosclerosis. (2009) (21)
- Citreorosein, a naturally occurring anthraquinone derivative isolated from Polygoni cuspidati radix, attenuates cyclooxygenase-2-dependent prostaglandin D2 generation by blocking Akt and JNK pathways in mouse bone marrow-derived mast cells. (2012) (20)
- Functional crosstalk between phospholipase D2 and signaling phospholipase A2/cyclooxygenase‐2‐mediated prostaglandin biosynthetic pathways (2000) (20)
- Detection of secretory phospholipase A2s related but not identical to type IIA isozyme in cultured mast cells (1997) (20)
- Role of type IIA secretory phospholipase A2 in arachidonic acid metabolism. (1999) (20)
- Degranulation and cytokine expression in human cord blood-derived mast cells cultured in serum-free medium with recombinant human stem cell factor. (2003) (20)
- Butyrate inhibits oral cancer cell proliferation and regulates expression of secretory phospholipase A2-X and COX-2. (2007) (19)
- Expression and Function of Group IIE Phospholipase A2 in Mouse Skin* (2016) (18)
- Different Functional Aspects of the Group II Subfamily (Types IIA and V) and Type X Secretory Phospholipase A2s in Regulating Arachidonic Acid Release and Prostaglandin Generation (1999) (18)
- Coupling between cyclooxygenases and prostaglandin F2α synthase: Detection of an inducible, glutathione-activated, membrane-bound prostaglandin F2α-synthetic activity (2003) (18)
- Type II phospholipase A2 is linked to cyclooxygenase-2-mediated delayed prostaglandin D2 generation by cultured mouse mast cells following FcepsilonRI- and cytokine-dependent activation. (1996) (18)
- Primary cilium suppression by SREBP1c involves distortion of vesicular trafficking by PLA2G3 (2015) (17)
- An anti-sulfatide antibody O4 immunoprecipitates sulfatide rafts including Fyn, Lyn and the G protein α subunit in rat primary immature oligodendrocytes (2013) (16)
- Prostaglandin E2-EP4 Axis Promotes Lipolysis and Fibrosis in Adipose Tissue Leading to Ectopic Fat Deposition and Insulin Resistance. (2020) (16)
- Role of type II phospholipase A2 in the inflammatory process of carrageenan‐induced pleurisy in rats (1994) (15)
- Secreted phospholipase A2 modifies extracellular vesicles and accelerates B cell lymphoma. (2022) (15)
- Monoclonal antibodies against human synovial phospholipase A2. (1990) (15)
- Function of type II phospholipase A2 in dopamine secretion by rat neuronal PC12 cells. (1996) (14)
- Phospholipase A2 in skin biology: new insights from gene-manipulated mice and lipidomics (2018) (14)
- Induction of PYPAF1 during in vitro maturation of mouse mast cells. (2003) (14)
- Group IIA secretory phospholipase A2 is a unique 12/15-lipoxygenase-regulated gene in cytokine-stimulated rat fibroblastic 3Y1 cells. (2004) (14)
- The interaction of secreted phospholipase A2-IIA with the microbiota alters its lipidome and promotes inflammation (2022) (14)
- Autophagy Is Required for Maturation of Surfactant-Containing Lamellar Bodies in the Lung and Swim Bladder. (2020) (13)
- Group V secreted phospholipase A2 plays a protective role against aortic dissection (2020) (12)
- The orphan nuclear receptor NR4A1 promotes FcεRI‐stimulated mast cell activation and anaphylaxis by counteracting the inhibitory LKB1/AMPK axis (2019) (12)
- Saucerneol D inhibits eicosanoid generation and degranulation through suppression of Syk kinase in mast cells. (2012) (12)
- Red-kerneled rice proanthocyanidin inhibits arachidonate 5-lipoxygenase and decreases psoriasis-like skin inflammation. (2020) (11)
- Dynamics and participation of type II phospholipase A2 in rat zymosan-induced pleurisy. (1993) (11)
- Coronavirus-specific antibody production in middle-aged mice requires phospholipase A2G2D. (2021) (10)
- Functional coupling between phospholipase A2S and cyclooxygenases in immediate and delayed prostanoid biosynthetic pathways. (2002) (10)
- Upregulation of ANGPTL6 in mouse keratinocytes enhances susceptibility to psoriasis (2016) (10)
- Integrated Lipidomics in the Secreted Phospholipase A2 Biology (2011) (10)
- Group IIA secreted phospholipase A2 controls skin carcinogenesis and psoriasis by shaping the gut microbiota (2022) (10)
- Mast cells mediate neutrophil recruitment and vascular leakage through the NLRP3 inflammasome in histamine-independent urticaria (2009) (10)
- Change in phospholipid composition of mouse bone marrow-derived mast cells during cultivation with fibroblasts. (1992) (10)
- Glycoconjugates with NeuAc-NeuAc-Gal-Glc are more effective at preventing adhesion of Helicobacter pylori to gastric epithelial cells than glycoconjugates with NeuAc-Gal-Glc. (2004) (10)
- Phospholipase A2 Group III and Group X Have Opposing Associations with Prognosis in Colorectal Cancer. (2015) (9)
- Citreorosein inhibits production of proinflammatory cytokines by blocking mitogen activated protein kinases, nuclear factor-κB and activator protein-1 activation in mouse bone marrow-derived mast cells. (2012) (9)
- Altered cytokine expression in mesenteric lymph nodes in a rat strain (Matsumoto Eosinophilic Shinshu) that spontaneously develops hypereosinophilia (2005) (9)
- A Gastrointestinal Calpain Complex, G-calpain, Is a Heterodimer of CAPN8 and CAPN9 Calpain Isoforms, Which Play Catalytic and Regulatory Roles, Respectively* (2016) (9)
- Effects of indomethacin and rofecoxib on gastric mucosal damage in normal and Helicobacter pylori-infected mongolian gerbils. (2004) (9)
- The expression of phospholipase A2 group X is inversely associated with metastasis in colorectal cancer (2012) (8)
- Exogenous type-II phospholipase A2 stimulates prostaglandin synthesis in rat liver-derived BRL-3A cells in the presence of tumor necrosis factor alpha. (1995) (8)
- Coupling between cyclooxygenases and prostaglandin F(2alpha) synthase. Detection of an inducible, glutathione-activated, membrane-bound prostaglandin F(2alpha)-synthetic activity. (2003) (8)
- Cellular arachidonate-releasing functions of various phospholipase A2s. (2003) (8)
- Old but New: Group IIA Phospholipase A2 as a Modulator of Gut Microbiota (2022) (7)
- Saucerneol F inhibits tumor necrosis factor-α and IL-6 production by suppressing Fyn-mediated pathways in FcεRI-mediated mast cells. (2013) (7)
- Characterization of heparin low-affinity phospholipase A1 present in brain and testicular tissue. (1999) (7)
- Polyunsaturated fatty acids potentiate interleukin-1-stimulated arachidonic acid release by cells overexpressing type IIA secretory phospholipase A 2 (1999) (7)
- Group IVE cytosolic phospholipase A2 limits psoriatic inflammation by mobilizing the anti‐inflammatory lipid N‐acylethanolamine (2022) (7)
- Regulatory functions of prostaglandin E2 synthases. (2003) (7)
- Preventive effect of Dioscorea japonica on squamous cell carcinoma of mouse skin involving down-regulation of prostaglandin E2 synthetic pathway (2018) (6)
- Change in sensitivity to lysophosphatidylserine of mouse bone marrow-derived mast cells during cultivation with fibroblasts. (1991) (6)
- Phospholipase A 2 (2015) (6)
- Diversity of Phospholipase A 2 Enzymes (6)
- [Lipid networks in mast cell biology]. (2011) (6)
- Cytosolic Phospholipase A2a Interacts With Microtubules (2002) (6)
- Cytokine Regulation of Mast Cell Protease Phenotype and Arachidonic Acid Metabolism (1994) (6)
- Tissue- and dose-dependent alteration of stress-inducible proteins by beta2-adrenoceptor agonist, salbutamol, in rats. (2005) (5)
- A new restriction endonuclease from Acetobacter pasteurianus (ApaLI). (1985) (5)
- Anti-inflammatory activity of hexane extracts from bones and internal organs of Anguilla japonica suppresses cyclooxygenase-2-dependent prostaglandin D₂ generation in mast cells and anaphylaxis in mice. (2013) (5)
- Critical amino acids responsible for converting specificities of proteins and for enhancing enzyme evolution are located around β-turn potentials: Data-based prediction (1993) (5)
- A negative regulator of delayed prostaglandin D2 production in mouse mast cells. (2008) (5)
- Post-transcriptional regulation of LTC4 synthase activity by retinoic acid in rat basophilic leukemia cells. (1997) (5)
- Bioactive Lipid Mediators (2015) (5)
- Characterization of cytosolic phospholipase A2 in rat mastocytoma RBL-2H3. (1994) (5)
- Characteristics and possible functions of mast cell phospholipases A2. (1992) (5)
- Cytosolic phospholipase A2 alpha interacts with microtubules. (2002) (5)
- BETA-(N-ACETYLGLUCOSAMINE)-N-GLYCOSIDASE: AN ENZYME WHICH CATALYZES THE HYDROLYSIS OF 1-BETA-ASPARTYL-2-ACETAMIDO-1,2-DIDEOXY-D-GLUCOSYLAMINE. (1965) (4)
- Critical amino acids responsible for conferring calcium channel characteristics are located on the surface and aroundβ-turn potentials of channel proteins (1995) (4)
- Purification, Properties and Recognition Sequence of Site-specific Restriction Endonuclease from Gluconobacter cerinus IFO 3285 (1985) (4)
- Type IIA secretory PLA2-mediated delayed PGE2 biosynthesis is regulated by the products of the cytosolic PLA2. (2002) (4)
- In vivo localization of secretory type V phospholipase A2 (sPLA2-V) in human salivary glands under normal and pathological conditions (2009) (4)
- Segregated Functions of Two Cytosolic Phospholipase A2 Isoforms (cPLA2α and cPLA2ε) in Lipid Mediator Generation. (2022) (4)
- Transgenic Expression of Group V, but Not Group X, Secreted Phospholipase A 2 in Mice Leads to Neonatal Lethality (2006) (4)
- Regulatory Roles of Phospholipase A2 Enzymes and Bioactive Lipids in Mast Cell Biology (2022) (4)
- Lack of Phospholipase A 2 Receptor Increases Susceptibility to Cardiac Rupture After Myocardial Infarction (2014) (4)
- Lipid Networks in Mast Cell Biology (2011) (4)
- [Toxicity profile of silodosin (KMD-3213)]. (2006) (3)
- Lysophosphatidylserine enhances exogenous type II phospholipase A2-induced activation of rat serosal mast cells. (1996) (3)
- Mast Cell-Specific Deletion of Group III Secreted Phospholipase A2 Impairs Mast Cell Maturation and Functions (2021) (3)
- Preparation of antibodies to phospholipases A2. (1991) (3)
- Characterization and molecular cloning of mouse type II phospholipase A2. (1997) (3)
- Hepatic phosphatidylcholine catabolism driven by PNPLA7 and PNPLA8 supplies endogenous choline to replenish the methionine cycle with methyl groups. (2023) (3)
- Resonant Recognition Model of Neuropeptide Y Family: Hot Spot Amino Acid Distribution in the Sequences (2000) (3)
- Positive and negative roles of lipids in mast cells and allergic responses. (2021) (3)
- Immunological Regulation by Bioactive Lipids. (2017) (3)
- Characterization of restriction endonuclease BdiSI, an isoschizomer of SfeI, from Bacteroides distasonis strain S-7. (1991) (2)
- Physiological Roles of Group X-secreted Phospholipase A 2 in Reproduction, Gastrointestinal Phospholipid Digestion, and (2011) (2)
- Comparison of recombinant types IIA, V and IIC phospholipase A2S, the three related mammalian secretory phospholipase A2 isozymes. (1999) (2)
- Another way for sPLA2 to meet with cells (2003) (2)
- Phospholipase A2 in Inflamed Tissues and Inflammatory Exudates (1997) (2)
- A New Restriction Endonuclease fromAcetobacter pasteurianus(ApaLl) (1985) (2)
- Analysis of Two Major Intracellular Phospholipase A 2 s in Mast Cells Reveals Crucial Contribution of cPLA 2 α , not iPLA 2 β , to Lipid Mobilization in Proximal Mast Cells and Distal Fibroblasts (2011) (2)
- Formation of N-acyl-phosphatidylethanolamines by cytosolic phospholipase A2ε in an ex vivo murine model of brain ischemia. (2022) (2)
- Purification, properties and recognition sequence and cleavage site determinations of restriction endonuclease from Acetobacter pasteurianus IFO 13753 (ApaLI). (1990) (2)
- Abnormal male reproduction and embryonic development induced by downregulation of a phospholipid fatty acid-introducing enzyme Lpgat1 in zebrafish (2022) (2)
- Author Correction: Sirt1 negatively regulates FcεRI-mediated mast cell activation through AMPK- and PTP1B-dependent processes (2020) (2)
- Group V Secretory Phospholipase A2 Regulates Endocytosis of Acetylated LDL by Transcriptional Activation of PGK1 in RAW264.7 Macrophage Cell Line (2021) (1)
- Corrigendum to “Anti-inflammatory activity of hexane extracts from bones and internal organs of Anguilla japonica suppresses cyclooxygenase-2-dependent prostaglandin D2 generation in mast cells and anaphylaxis in mice” [Food Chem. Toxicol. 57 (2013) 307–313] (2014) (1)
- Special issue Phospholipases A2 and lipid mediators (2010) (1)
- Effect of feeding fish oil on uterine secretion of PGF 2 α , milk composition , and metabolic status of peri-parturient Holstein cows (2002) (1)
- [Functional coupling between phospholipase A2 and cyclooxygenase]. (1999) (1)
- Prostaglandin E2 synthase (2000) (1)
- The Lysophospholipase PNPLA7 Controls Hepatic Choline and Methionine Metabolism (2023) (1)
- Malabaricone C derived from nutmeg inhibits arachidonate 5-lipoxygenase activity and ameliorates psoriasis-like skin inflammation in mice. (2022) (1)
- Studies on a Mechanism by Which Cytosolic Phospholipase A 2 Regulates the Expression and Function of Type IIA Secretory (2000) (1)
- The restriction endonuclease GceinI of Gluconobacter cerinus IFO 3260, an isoschizomer of BamHI, has a monomeric structure. (1990) (1)
- [101] β-Aspartyl-N-acetylglucosaminadase from epididymis (1966) (1)
- Renoprotective Effect of the L/N-Type Calcium Channel Antagonist Cilnidipine on Puromycin Aminonucleoside-Induced Nephrosis in Rats (2009) (1)
- This information is current as-Deficient Mice Ndrg 1 Responses in Degranulation and Attenuated Allergic Impaired Mast Cell Maturation and (2007) (1)
- A new restriction endonuclease from Bacteroides distasonis (BdiI). (1990) (1)
- [Phospholipase A2 and inflammation]. (1996) (1)
- Regulation of prostaglandin, leukotriene, and platelet-activating factor metabolism in mast cells. (1999) (1)
- [Phospholipase A2]. (1999) (0)
- 324 Type-II PLA2 supplies arachidonic acid to PGHS-2 in the delayed phase of PGD2 generation by mouse mast cells (1996) (0)
- Changes in kinetic properties of cytosolic phospholipase A2 in activated rat neutrophils. (1997) (0)
- Lysophosphatidic acids regulates mast cell maturation (2015) (0)
- Modulation of immunity by the secreted phospholipase A2 family. (2023) (0)
- Aberrant activation of skin-specific CAPN12 is involved in development of psoriasis (2017) (0)
- Lipid profiling reveals the presence of unique lipid mediators in human milk from healthy and mastitic subjects. (2022) (0)
- Physiological roles of secreted phospholipase A2 enzymes (2008) (0)
- Phospholipase A2 in skin biology: new insights from gene-manipulated mice and lipidomics (2018) (0)
- [LIPIDS IN ALLERGIC DISEASES]. (2020) (0)
- Lipid-Orchestrated Acceleration of Epstein-Barr Virus-Induced B-Cell Lymphoma Via the Secreted Phospholipase A 2-Mediated Modification of Exosomes (2021) (0)
- Skeletal muscle weakness and atrophy in membrane-associated calcium-independent phospholipase A2 (iPLA2γ)-deficient mice (2009) (0)
- Effect of red rice proanthocyanidin on prostaglandin E 2 production (2017) (0)
- Purification, Properties and Recognition Sequence and Cleavage Site Determinations of Restriction Endonuclease from Acetobacter pasteurianus IFO 13753 (ApaIA)f (2006) (0)
- Functional linkage between secretory phospholipase A2 (sPLA2) and membrane-bound prostaglandin E2 synthase (mPGES) (2002) (0)
- The phospholipase A2 superfamily as a central hub of bioactive lipids and beyond. (2023) (0)
- Blue light alters cellular lipidome—Light-induced lipidomic changes can be modulated by optogenetically engineered cPLA2α (2022) (0)
- Age-related dysregulation in the lipidome compromises the immune response to the severe acute respiratory coronavirus (VIR5P.1140) (2015) (0)
- β-(N-Acetylglucosamine)-N-glycosidase: an Enzyme Which Catalyzes the Hydrolysis of 1-β-Aspartyl-2-acetamido-1,2-dideoxy-d-glucosylamine (1965) (0)
- Mini Review Inflammation and Regeneration (2009) (0)
- Direct methane production from baiomass by co-culture of anaerobic fungus, Neocallimastix frontalis and methanogens. (1999) (0)
- [Arachidonate metabolism in mast cells]. (1997) (0)
- Analysis of viral replication regulating factors in bovine leukemia virus using chemical biology approach (2019) (0)
- Type IIA sPLA2-mediated delayed pge2 biosynthesis is regulated by the product(s) of the cPLA2 and 12-lipoxygenase pathway (1999) (0)
- The Restriction Endonuclease GceinI of Gluconobacter cerinus IFO 3260, an Isoschizomer of BamHI, Has a Monomeric Structure(Microbiology & Fermentation Industry) (1990) (0)
- Simulation of ATP Hydrolysis with Table Form (2011) (0)
- Functional coupling among phospholipase A2s, cyclooxygenases, and terminal prostaglandin synthases in immediate and delyed prostanoid biosynthetic pathways (1999) (0)
- Author Correction: Sirt1 negatively regulates FcεRI-mediated mast cell activation through AMPK- and PTP1B-dependent processes (2020) (0)
- Sirt1 negatively regulates FcεRI-mediated mast cell activation through AMPK- and PTP1B-dependent processes (2017) (0)
- The role of oxidized phaspholipid-derived lipid mediators in IgE-mediated mast cell activation (2016) (0)
- [New insights into the roles of secreted phospholipase A2s in immunity]. (2014) (0)
- Influences of Lactobacillus and Cellobiose on the Composition and Metabolic Activity of Fecal Microbiota in Dogs given Boiled Chicken Head and Cow Milk (2008) (0)
- Phospholipase A2 as a Potential Drug Target for Airway Disorders (2011) (0)
- Matrix Metalloproteinase-2 Negatively Regulates Cardiac Secreted Phospholipase A 2 to Modulate In fl ammation and Fever (2015) (0)
- Strain differences in phenobarbital metabolism between SD and Wistar rats(Proceedings of the 32nd Annual Meeting) (2005) (0)
- Purification and characterization of cow milk lipocalin-type prostaglandin D synthase as a potential biomarker of bovine mastitis (2017) (0)
- 2 Phospholipase A and Function of Type IIA Secretory Regulates the Expression 2 Phospholipase A Studies on a Mechanism by Which Cytosolic (2000) (0)
- Lipid mediators in immune reactions (WS-106) Chairpersons: Takehiko Yokomizo, Satoshi Ishii (2010) (0)
- Prostaglandin D in the Regulation of Degranulation and 2 II Subfamily of Secretory Phospholipases A Granule-Associated Heparin-Binding Group Redundant and Segregated Functions of (2000) (0)
- Organism-Wide Analysis of Sepsis Reveals Mechanisms of Systemic Inflammation (2023) (0)
- Biosynthesis in Rat Peritoneal Macrophages Synthases in Different Phases of Prostanoid Cyclooxygenases, and Terminal Prostanoid ,2 Segregated Coupling of Phospholipases A (1998) (0)
- secreted phospholipase A 2 transgenic mice spontaneously develop inflammation (2009) (0)
- Group III phospholipase A2 promotes colitis and colorectal cancer (2017) (0)
- Characterization of restriction endonuclease CbiI, an isoschizomer of AsuII, from Clostridium bifermentans strain B-4. (1991) (0)
- A New Restriction Endonuclease fromBacteroides distasonis(BdiI) (1990) (0)
- An anti-sulfatide antibody O4 immunoprecipitates sulfatide rafts including Fyn, Lyn and the G protein α subunit in rat primary immature oligodendrocytes (2013) (0)
- The Roles of sPLA2s in Skin Homeostasis and Disease (2023) (0)
- COMPARISON OF RECOMBINANT TYPES IIA, V AND IIC PHOSPHOLIPASE A2S, THE THREE RELATED MAMMALIAN SECRETORY PHOSPHOLIPASE A2ISOZYMES INTRODUCTION (0)
- Hypercholesterolemic Dysregulation of Calpain in Lymphatic Endothelial Cells Interferes With Regulatory T-Cell Stability and Trafficking (2022) (0)
- [Phospholipase A2]. (2020) (0)
- PAF & Arachidonic Acid Cascade (2014) (0)
- Metabolic regulation by secreted phospholipase A2 (2016) (0)
- Identification of sPLA2 that promotes adipocyte beiging. (2017) (0)
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What Schools Are Affiliated With Makoto Murakami?
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