Manu Platt

Q: What Schools Are Affiliated With Manu Platt

Manu Platt is affiliated with the following schools: Emory University, Massachusetts Institute of Technology, Georgia Tech

Manu Platt's AcademicInfluence.com Rankings

Manu Platt

Engineering

#8693

World Rank

#10291

Historical Rank

Biomedical Engineering

#886

World Rank

#902

Historical Rank

engineering Degrees

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Engineering

Manu Platt's Degrees

PhD Biomedical Engineering Georgia Tech
Bachelors Chemical Engineering Georgia Tech

Why Is Manu Platt Influential?

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According to Wikipedia, Manu Omar Platt is an American biomedical engineer who is a professor at the Georgia Institute of Technology Wallace H. Coulter Department of Biomedical Engineering. He serves as Diversity Director of the Center on Emergent Behaviors of Integrated Cellular Systems.

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Manu Platt's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Bone Morphogenic Protein 4 Produced in Endothelial Cells by Oscillatory Shear Stress Induces Monocyte Adhesion by Stimulating Reactive Oxygen Species Production From a Nox1-Based NADPH Oxidase (2004) (387)
Bone Morphogenic Protein 4 Produced in Endothelial Cells by Oscillatory Shear Stress Stimulates an Inflammatory Response* (2003) (297)
Identification of Therapeutic Covariant MicroRNA Clusters in Hypoxia-Treated Cardiac Progenitor Cell Exosomes Using Systems Biology (2015) (288)
Sickle cell biomechanics. (2010) (249)
Magnesium as a biodegradable and bioabsorbable material for medical implants (2009) (224)
Simulated microgravity using the Random Positioning Machine inhibits differentiation and alters gene expression profiles of 2T3 preosteoblasts. (2005) (130)
Experimental, Systems, and Computational Approaches to Understanding the MicroRNA-Mediated Reparative Potential of Cardiac Progenitor Cell–Derived Exosomes From Pediatric Patients (2017) (124)
Expression of cathepsin K is regulated by shear stress in cultured endothelial cells and is increased in endothelium in human atherosclerosis. (2007) (111)
Sustained epidermal growth factor receptor levels and activation by tethered ligand binding enhances osteogenic differentiation of multi‐potent marrow stromal cells (2009) (77)
Circulating exosomes derived from transplanted progenitor cells aid the functional recovery of ischemic myocardium (2019) (61)
Crohn's disease: a review of treatment options and current research. (2013) (61)
Acid sphingomyelinase is activated in sickle cell erythrocytes and contributes to inflammatory microparticle generation in SCD. (2014) (60)
Tumor cell–organized fibronectin maintenance of a dormant breast cancer population (2020) (60)
Manipulating substrate and pH in zymography protocols selectively distinguishes cathepsins K, L, S, and V activity in cells and tissues. (2011) (58)
VEGF internalization is not required for VEGFR-2 phosphorylation in bioengineered surfaces with covalently linked VEGF. (2011) (57)
Cyclic pressure and shear stress regulate matrix metalloproteinases and cathepsin activity in porcine aortic valves. (2006) (55)
Age-Dependent Effect of Pediatric Cardiac Progenitor Cells After Juvenile Heart Failure (2016) (54)
Muscadine grape skin extract can antagonize Snail-cathepsin L-mediated invasion, migration and osteoclastogenesis in prostate and breast cancer cells. (2015) (51)
Multiplex Zymography Captures Stage-specific Activity Profiles of Cathepsins K, L, and S in Human Breast, Lung, and Cervical Cancer (2011) (50)
Multipathway Kinase Signatures of Multipotent Stromal Cells Are Predictive for Osteogenic Differentiation (2009) (47)
Detection of femtomole quantities of mature cathepsin K with zymography. (2010) (46)
Laminar shear stress inhibits cathepsin L activity in endothelial cells (EC) (2006) (41)
Tumor necrosis factor alpha stimulates cathepsin K and V activity via juxtacrine monocyte–endothelial cell signaling and JNK activation (2012) (38)
Laminar Shear Stress Inhibits Cathepsin L Activity in Endothelial Cells (2006) (37)
Heat shock and cold shock in Deinococcus radiodurans (2007) (36)
MMP-mediated mesenchymal morphogenesis of pluripotent stem cell aggregates stimulated by gelatin methacrylate microparticle incorporation. (2016) (36)
Sickle Cell Disease Activates Peripheral Blood Mononuclear Cells to Induce Cathepsins K and V Activity in Endothelial Cells (2012) (35)
Cathepsin S Cannibalism of Cathepsin K as a Mechanism to Reduce Type I Collagen Degradation* (2012) (33)
Endothelial cells and cathepsins: Biochemical and biomechanical regulation. (2016) (30)
Patient specific proteolytic activity of monocyte-derived macrophages and osteoclasts predicted with temporal kinase activation states during differentiation. (2012) (30)
Multiple sites on SARS‐CoV‐2 spike protein are susceptible to proteolysis by cathepsins B, K, L, S, and V (2021) (29)
Endothelial Dysfunction, Arterial Stiffening, and Intima-Media Thickening in Large Arteries from HIV-1 Transgenic Mice (2013) (28)
Monocyte-derived macrophage assisted breast cancer cell invasion as a personalized, predictive metric to score metastatic risk (2015) (22)
Investigating the Life Expectancy and Proteolytic Degradation of Engineered Skeletal Muscle Biological Machines (2017) (19)
Azidothymidine (AZT) leads to arterial stiffening and intima-media thickening in mice. (2013) (18)
Long-Term Cryopreservation and Revival of Tissue-Engineered Skeletal Muscle. (2019) (16)
Differential cathepsin responses to inhibitor-induced feedback: E-64 and cystatin C elevate active cathepsin S and suppress active cathepsin L in breast cancer cells. (2016) (16)
Original Research: Sickle cell anemia and pediatric strokes: Computational fluid dynamics analysis in the middle cerebral artery (2016) (14)
Cathepsin Protease Inhibition Reduces Endometriosis Lesion Establishment (2016) (13)
Predicting Functional Responses of Progenitor Cell Exosome Potential with Computational Modeling (2019) (13)
Kinin-B2 receptor exerted neuroprotection after diisopropylfluorophosphate-induced neuronal damage (2013) (13)
Development of a Platform for Studying 3D Astrocyte Mechanobiology: Compression of Astrocytes in Collagen Gels (2018) (11)
Microarchitectural and mechanical characterization of the sickle bone. (2015) (10)
Human cathepsins K, L, and S: Related proteases, but unique fibrinolytic activity. (2018) (10)
Cathepsins in Rotator Cuff Tendinopathy: Identification in Human Chronic Tears and Temporal Induction in a Rat Model (2015) (10)
Supraspinatus tendon overuse results in degenerative changes to tendon insertion region and adjacent humeral cartilage in a rat model (2017) (10)
Systematic Optimization of Multiplex Zymography Protocol to Detect Active Cathepsins K, L, S, and V in Healthy and Diseased Tissue: Compromise Among Limits of Detection, Reduced Time, and Resources (2013) (9)
We exist. We are your peers. (2020) (9)
Computational predictions of cysteine cathepsin‐mediated fibrinogen proteolysis (2018) (9)
Implementation and evaluation of a biotechnology research experience for African-American high school students. (2019) (8)
Pro-Atherogenic Shear Stress and HIV Proteins Synergistically Upregulate Cathepsin K in Endothelial Cells (2014) (8)
Full‐thickness rotator cuff tear in rat results in distinct temporal expression of multiple proteases in tendon, muscle, and cartilage (2018) (8)
Computational imaging analysis of glycated fibrin gels reveals aggregated and anisotropic structures. (2017) (7)
Low-Cost Method to Monitor Patient Adherence to HIV Antiretroviral Therapy Using Multiplex Cathepsin Zymography (2015) (7)
Sequential, but not Concurrent, Incubation of Cathepsin K and L with Type I Collagen Results in Extended Proteolysis (2019) (7)
PACMANS: A bioinformatically informed algorithm to predict, design, and disrupt protease‐on‐protease hydrolysis (2017) (7)
How do Black Lives Matter in Teaching, Lab Practices, and Research? (2017) (7)
Reassessing enzyme kinetics: Considering protease-as-substrate interactions in proteolytic networks (2020) (7)
Implementation of a Biomedical Engineering Research Experience for African-American High School Students at a Tier One Research University. (2018) (7)
Biomechanical and biochemical regulation of cathepsin K expression in endothelial cells converge at AP-1 and NF-κB (2016) (6)
Quantitative biosciences from nano to macro Indexed in MEDLINE ! (2011) (6)
Metabolomics and cytokine profiling of mesenchymal stromal cells identify markers predictive of T-cell suppression. (2021) (6)
Computational imaging analysis of fibrin matrices with the inclusion of erythrocytes from homozygous SS blood reveals agglomerated and amorphous structures (2016) (5)
Tumor cell-organized fibronectin is required to maintain a dormant breast cancer population (2019) (4)
Experimental and imaging techniques for examining fibrin clot structures in normal and diseased states. (2015) (4)
Efavirenz treatment causes arterial stiffening in apolipoprotein E-null mice. (2015) (4)
Molecular insights into the irreversible mechanical behavior of sickle hemoglobin (2019) (4)
Sickle Cell Anemia Mediates Carotid Artery Expansive Remodeling That Can Be Prevented by Inhibition of JNK (c-Jun N-Terminal Kinase) (2020) (4)
Novel in vivo and in vitro techniques to image and model the cerebral vasculature in sickle cell disease. (2017) (3)
Genetic Mutations Associated with Hormone-Positive Breast Cancer in a Small Cohort of Ethiopian Women (2021) (3)
Using Statistical Modeling to Understand and Predict Pediatric Stem Cell Function. (2019) (3)
Co-Emergence of Specialized Endothelial Cells from Embryonic Stem Cells. (2018) (3)
Cysteine cathepsins are altered by flow within an engineered in vitro microvascular niche (2020) (3)
OSCILLATORY SHEAR STRESS (OS) UPREGULATES CATHEPSIN EXPRESSION WHILE INHIBITING CYSTATIN C EXPRESSION IN ENDOTHELIAL CELLS (EC) - IMPLICATION IN ATHEROSCLEROSIS (2004) (1)
ANTIRETROVIRAL DRUGS EFAVIRENZ AND TENOFOVIR AND THEIR EFFECTS ON ARTERIAL REMODELING AND PROTEASE ACTIVITY (2013) (1)
Abstract C60: Snail transcription factor contributes to bone metastasis in prostate and breast cancer cells (2014) (1)
Comparative analysis of arterial compliance in mice genetically null for cathepsins K, L, or S. (2022) (1)
Age and Sex Determinants of Bone Phenotype in a Transgenic Mouse Model of Sickle Cell Disease (2012) (1)
Dynamic Model of Protease State and Inhibitor Trafficking to Predict Protease Activity in Breast Cancer Cells (2019) (1)
Age-dependent characterization of carotid and cerebral artery geometries in a transgenic mouse model of sickle cell anemia using ultrasound and microcomputed tomography. (2020) (1)
Fibrinolytic Activity of Cysteine Cathepsins and Role of Fibrin as a Reservoir to Sustain Proteolysis (2018) (1)
Sickle cell disease promotes sex-dependent pathological bone loss through enhanced cathepsin proteolytic activity in mice (2021) (1)
Tumor necrosis factor alpha stimulates cathepsin K and V activity via juxtacrine monocyte–endothelial cell signaling and JNK activation (2012) (1)
From GRID to gridlock: the relationship between scientific biomedical breakthroughs and HIV/AIDS policy in the US Congress (2013) (1)
In Memoriam Robert M. Nerem, 1937-2020. (2020) (0)
Abstract B062: Genetic driving factors of aggressive Ethiopian breast cancer (2020) (0)
[Illinois] Extracellular Matrix Remodeling during Cancer Progression and Metastasis (2014) (0)
T-cell phosphokinome as a fingerprint of effective graft versus leukemia. (2012) (0)
Investigating the Life Expectancy and Proteolytic Degradation of Engineered Skeletal Muscle Biological Machines (2017) (0)
Cathepsins and Other Proteases in Tumor Angiogenesis (2013) (0)
In Memoriam Robert M. Nerem, 1937-2020. (2020) (0)
Cathepsin Cannibalism Reduces Collagen And Elastin Degradation In Matrix Remodeling (2014) (0)
Optimizing activation and purification for cathepsin proteases from engineered cell (2018) (0)
Low-Cost Method to Monitor Patient Adherence to HIV Antiretroviral Therapy Using Multiplex Cathepsin (0)
Challenges and Opportunities Modeling the Dynamic Tumor Matrisome (2023) (0)
Race, Reparations and Reconciliation After the Genome (2017) (0)
Abstract C57: Snail transcription factor can regulate cathepsin L activity in prostate carcinomas (2014) (0)
Consecutive, But Not Concurrent, Cathepsin Incubation with Type I Collagen Results in Extended Proteolysis (2018) (0)
“What’s Eating You?” Quantifying Proteolytic Activity in Health and Disease with Novel Assays and Computational Models (2011) (0)
Elastic lamina fragmentation in sickle mice can be rescued by JNK‐Cathepsin inhibition (2018) (0)
Bone Microenvironment Tissue Surrogates Engineered for Reporting of Metastasized Breast Cancer Osteolytic Activity (2014) (0)
Dynamic Model of Protease State and Inhibitor Trafficking to Predict Protease Activity in Breast Cancer Cells (2019) (0)
Abstract 16340: Experimental, Systems and Computational Approaches to Understand the Microrna-Mediated Reparative Potential of Cardiac Progenitor Cell-Derived Exosomes From Pediatric Patients (2016) (0)
Abstract TP261: Spontaneous Strokes In Sickle Cell Transgenic Mice Captured Ex Vivo With Magnetic Resonance Imaging (2013) (0)
Platt Lab Overview (2009) (0)
Go Jackets! Oral Presentation Sessions Student Center, 3rd Floor Pan-cancer Analysis for Studying Cancer Stage Using Protein Expression Data Robustness Analysis of the Total Cavopulmonary Connection with Steady and Pulsatile Computational Fluid Dynamics Simulations Finding Meaning in Text: Parsing S (0)
Modeling collective cell behavior in cancer: Perspectives from an interdisciplinary conversation. (2023) (0)
Protease‐protease interactions as a microenvironment‐dependent regulatory mechanism (2018) (0)
Abstract 4105: Cathepsin L inhibition reverts epithelial mesenchymal transition in prostate and breast cancer cells (2015) (0)
Development of a Platform for Studying 3D Astrocyte Mechanobiology: Compression of Astrocytes in Collagen Gels (2017) (0)
Chapter Cathepsins and Other Proteases in Tumor Angiogenesis (2013) (0)
RSC_IB_C2IB20197F 1..11 (2012) (0)
Pro-Atherogenic Shear Stress and HIV Proteins Synergistically Upregulate Cathepsin K in Endothelial Cells (2014) (0)
Effects of Red Blood Cell Sickling on Right Ventricular Afterload in vivo (2020) (0)
Quantitative phase imaging of sickle cell disease effects on mouse brain vasculature using quantitative oblique back-illumination microscopy (2023) (0)
Integration of Nanoscale and Macroscale cues in Bone Regeneration (2009) (0)
The Mechanical and Structural Effects of HIV Proteins on Murine Carotid Arteries (2011) (0)
RED CELLS , IRON , AND ERYTHROPOIESIS Acid sphingomyelinase is activated in sickle cell erythrocytes and contributes to in fl ammatory microparticle generation in SCD (2014) (0)
Genetic Mutations Associated with Hormone-Positive Breast Cancer in Ethiopian Women (2020) (0)
Age-dependent characterization of the carotid and cerebral artery morphologies in a transgenic mouse model of sickle cell anemia using ultrasound and microcomputed tomography (2019) (0)
Abstract 1457: Oscillatory and Laminar Shear Stress Inversely Regulate Cathepsins K and S and Cystatin C in Mouse Aortic Endothelial Cells (MAEC) (2006) (0)
Multi-omics characterization of mesenchymal stem/stromal cells for the identification of putative critical quality attributes (2021) (0)
in human atherosclerosis cultured endothelial cells and is increased in endothelium Expression of cathepsin K is regulated by shear stress in (2016) (0)
Investigating liver fibrosis in a humanized mice model of sickle cell disease (2021) (0)
Multiplex Cathepsin Zymography to Detect Amounts of Active Cathepsins K, L, S, and V. (2017) (0)
Sequential, but not Concurrent, Incubation of Cathepsin K and L with Type I Collagen Results in Extended Proteolysis (2019) (0)
Pharmacological Protease Inhibitor Preserves Proteolytic Activity In Breast Cancer Cells: Computational Models To Probe Unexpected Cellular Responses (2018) (0)
Abstract 477: Using Computational Models to Predict Stem Cell Function (2018) (0)
Role of Shear Stress in the Differential Regulation of Endothelial Cathepsins and Cystatin C (2006) (0)
Cathepsins in Rotator Cuff Tendinopathy: Identification in Human Chronic Tears and Temporal Induction in a Rat Model (2015) (0)
The Mechanical and Structural Changes in Murine Arteries due to the Antiretroviral Drug Azidothymidine (AZT) (2012) (0)

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Other Resources About Manu Platt

en.wikipedia.org

What Schools Are Affiliated With Manu Platt?

Manu Platt is affiliated with the following schools:

Manu Platt's Academic­Influence.com Rankings