Manuel Benedikt Graeber
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Manuel Benedikt Graeberbiology Degrees
Biology
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#14485
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Genetics
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Neuroscience
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#1838
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Biology
Manuel Benedikt Graeber's Degrees
- PhD Neuroscience University of California, San Francisco
- Bachelors Biology Stanford University
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Why Is Manuel Benedikt Graeber Influential?
(Suggest an Edit or Addition)Manuel Benedikt Graeber's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- AlaSOPro mutation in the gene encoding α-synuclein in Parkinson's disease (1998) (2454)
- Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease. (1998) (2074)
- Functional plasticity of microglia: A review (1988) (970)
- PGC-1α, A Potential Therapeutic Target for Early Intervention in Parkinson’s Disease (2010) (699)
- Changing Face of Microglia (2010) (570)
- Axotomy of the rat facial nerve leads to increased CR3 complement receptor expression by activated microglial cells (1988) (379)
- Staging of Neurofibrillary Pathology in Alzheimer's Disease: A Study of the BrainNet Europe Consortium (2008) (371)
- Microglia in brain tumors (2002) (358)
- Role of microglia in CNS inflammation (2011) (336)
- Microglial cells but not astrocytes undergo mitosis following rat facial nerve axotomy (1988) (331)
- The facial nerve axotomy model (2004) (308)
- Expression of Ia antigen on perivascular and microglial cells after sublethal and lethal motor neuron injury (1989) (294)
- Identity of ED2‐positive perivascular cells in rat brain (1989) (283)
- Microglial inflammation in the parkinsonian substantia nigra: relationship to alpha-synuclein deposition (2005) (264)
- The molecular profile of microglia under the influence of glioma. (2012) (245)
- Biomarkers for Parkinson's disease (2009) (229)
- New expression of myelomonocytic antigens by microglia and perivascular cells following lethal motor neuron injury (1990) (220)
- Whole genome expression profiling of the medial and lateral substantia nigra in Parkinson’s disease (2006) (206)
- Microglia: Immune Network in the CNS (1990) (201)
- Surveillance, intervention and cytotoxicity: is there a protective role of microglia? (1994) (197)
- Peripheral nerve lesion produces increased levels of major histocompatibility complex antigens in the central nervous system (1989) (197)
- Oligodendrogliomas: Reproducibility and Prognostic Value of Histologic Diagnosis and Grading (2001) (194)
- Positron emission tomography and functional characterization of a complete PBR/TSPO knockout (2014) (194)
- The case described by Alois Alzheimer in 1911 (1998) (191)
- The microglial cytoskeleton: vimentin is localized within activated cellsin situ (1988) (184)
- Delayed astrocyte reaction following facial nerve axotomy (1988) (180)
- The dorsal motor nucleus of the vagus is not an obligatory trigger site of Parkinson's disease: a critical analysis of α‐synuclein staging (2008) (172)
- The microglia/macrophage response in the neonatal rat facial nucleus following axotomy (1998) (165)
- Transformation of donor‐derived bone marrow precursors into host microglia during autoimmune CNS inflammation and during the retrograde response to axotomy (2001) (164)
- On the question of apoptosis in the parkinsonian substantia nigra (1997) (153)
- Microglial Activation in Alzheimer Disease: Association with APOE Genotype (1998) (152)
- Ultrastructural Location of Major Histocompatibility Complex (MHC) Class II Positive Perivascular Cells in Histologically Normal Human Brain (1992) (152)
- Assessment of β-amyloid deposits in human brain: a study of the BrainNet Europe Consortium (2009) (149)
- Cellular pathology of the central nervous system. (2002) (142)
- Dementia and visual hallucinations associated with limbic pathology in Parkinson's disease. (2009) (128)
- Mechanisms of Cell Death in Neurodegenerative Diseases: Fashion, Fiction, and Facts (2002) (125)
- Neuronal FasL Induces Cell Death of Encephalitogenic T Lymphocytes (2000) (120)
- Electron microscopy of tissue adherent to explanted electrodes in dystonia and Parkinson's disease. (2004) (111)
- Striatal &bgr;-Amyloid Deposition in Parkinson Disease With Dementia (2008) (105)
- Microglia and microglia-derived brain macrophages in culture: generation from axotomized rat facial nuclei, identification and characterization in vitro (1989) (105)
- Interlaboratory Comparison of Assessments of Alzheimer Disease-Related Lesions: A Study of the BrainNet Europe Consortium (2006) (102)
- The medial and lateral substantia nigra in Parkinson’s disease: mRNA profiles associated with higher brain tissue vulnerability (2007) (101)
- Microglia states and nomenclature: A field at its crossroads (2022) (99)
- Glutathione relates to neuropsychological functioning in mild cognitive impairment (2014) (98)
- Microglia and the Development of Spongiform Change in Creutzfeldt-Jakob Disease (1998) (95)
- Synaptic stripping in the human facial nucleus (2004) (94)
- Development of ramified microglia from early macrophages in the zebrafish optic tectum (2013) (93)
- Immunoelectron microscopic localization of laminin in normal and regenerating mouse sciatic nerve (1990) (92)
- CR3/43, a marker for activated human microglia: application to diagnostic neuropathology (1994) (92)
- Recent developments in the molecular genetics of mitochondrial disorders (1998) (90)
- Apolipoprotein E epsilon 4 allele, cognitive decline, and deterioration of everyday performance in Alzheimer's disease (1996) (89)
- Novel mutations of mitochondrial complex I in pathologically proven Parkinson disease (1998) (88)
- Perivascular microglia defined (1990) (87)
- Towards a pathway definition of Parkinson’s disease: a complex disorder with links to cancer, diabetes and inflammation (2008) (86)
- Microglia only weakly present glioma antigen to cytotoxic T cells (1999) (86)
- Increase of transferrin receptors and iron uptake in regenerating motor neurons (1989) (82)
- Association of the mitochondrial tRNAA4336G mutation with Alzheimer's and Parkinson's diseases (1997) (80)
- Analysis of mitochondrial targeting sequence and coding region polymorphisms of the manganese superoxide dismutase gene in German Parkinson disease patients. (1999) (79)
- A presenilin 1 mutation in the first case of Alzheimer's disease (2013) (78)
- Role of Mitochondria in Parkinson Disease (1999) (74)
- Population control of microglia: does apoptosisplay a role? (1997) (74)
- Histopathology and APOE genotype of the first Alzheimer disease patient, Auguste D. (1998) (73)
- Homocysteine-induced endoplasmic reticulum protein (herp) is up-regulated in parkinsonian substantia nigra and present in the core of Lewy bodies. (2009) (72)
- Correction: Microglial inflammation in the parkinsonian substantia nigra: relationship to alpha-synuclein deposition (2006) (70)
- Neuronal pentraxin II is highly upregulated in Parkinson’s disease and a novel component of Lewy bodies (2007) (65)
- Immunophenotypic characterization of rat brain macrophages in culture (1989) (62)
- The need to unify neuropathological assessments of vascular alterations in the ageing brain Multicentre survey by the BrainNet Europe consortium (2012) (60)
- ‘Neuroinflammation’ differs categorically from inflammation: transcriptomes of Alzheimer's disease, Parkinson's disease, schizophrenia and inflammatory diseases compared (2014) (59)
- Association of the mitochondrial tRNA(A4336G) mutation with Alzheimer's and Parkinson's diseases. (1997) (59)
- Comparative study of commercially available anti‐α‐synuclein antibodies (2006) (58)
- Towards a transcriptome definition of microglial cells (2004) (56)
- Contralateral early blink reflex in patients with facial nerve palsy: indication for synaptic reorganization in the facial nucleus during regeneration (1992) (54)
- Nucleo-cytoplasmic transport of TDP-43 studied in real time: impaired microglia function leads to axonal spreading of TDP-43 in degenerating motor neurons (2018) (53)
- Monocyte-Astrocyte Networks Regulate Matrix Metalloproteinase Gene Expression and Secretion in Central Nervous System Tuberculosis In Vitro and In Vivo1 (2007) (52)
- Delineation of the dystonia-parkinsonism syndrome locus in Xq13. (1992) (51)
- The apolipoprotein E epsilon 4 allele in Parkinson's disease with Alzheimer lesions. (1996) (51)
- Microglial proliferation in the brain of chronic alcoholics with hepatic encephalopathy (2014) (49)
- Mitochondrial NADH dehydrogenase and CYP2D6 genotypes in Lewy‐body Parkinsonism (1996) (49)
- 5'-Nucleotidase in postnatal ontogeny of rat cerebellum: a marker for migrating nerve cells? (1988) (48)
- No association of mutations at nucleotide 5460 of mitochondrial NADH dehydrogenase with Alzheimer's disease. (1994) (44)
- Two novel point mutations of mitochondrial tRNA genes in histologically confirmed Parkinson disease (1999) (44)
- Multiple mechanisms of microglia: A gatekeeper's contribution to pain states (2012) (42)
- Dystonia-parkinsonism syndrome (XDP) locus: flanking markers in Xq12-q21.1. (1992) (39)
- Regional heterogeneity of mtDNA heteroplasmy in parkinsonian brain. (1996) (38)
- IFN' synergizes with IL‐1α to up‐regulate MMP‐9 secretion in a cellular model of central nervous system tuberculosis (2007) (37)
- Neurodegeneration and aging: Role of the second genome (1998) (35)
- Quantitative immunohistochemistry in the rat facial nucleus with [125I]-iodinated secondary antibodies and in situ autoradiography: non-linear binding characteristics of primary monoclonal and polyclonal antibodies. (1993) (34)
- The role of glia in late-life depression (2012) (34)
- Hippocampal CA2 Lewy pathology is associated with cholinergic degeneration in Parkinson’s disease with cognitive decline (2019) (33)
- Synaptic 5'-nucleotidase is transient and indicative of climbing fiber plasticity during the postnatal development of rat cerebellum. (1991) (31)
- Use of neuropathological tissue for molecular genetic studies: parameters affecting DNA extraction and polymerase chain reaction (2004) (31)
- Genotype-Phenotype Correlation in Gemistocytic Astrocytomas (2001) (30)
- Low prevalence of apolipoprotein E epsilon 4 allele in the neurofibrillary tangle predominant form of senile dementia. (1997) (30)
- Microglia in Culture: What Genes Do They Express? (2004) (29)
- MICROGLIA IN GEMISTOCYTIC ASTROCYTOMAS (2007) (29)
- The microglial gene regulatory network activated by interferon-gamma (2007) (28)
- Neuroinflammation: No Rose by Any Other Name (2014) (25)
- Reaction on Motoneurons and Their Microenvironment to Axotomy (1986) (24)
- Expression of alpha-synuclein in non-apoptotic, slowly degenerating facial motoneurones (2001) (24)
- The third glial cell type, the microglia: cellular markers of activation in situ. (1990) (24)
- Parkinson disease: analysis of mitochondrial DNA in monozygotic twins (2000) (23)
- Neuropathological assessments of the pathology in frontotemporal lobar degeneration with TDP43-positive inclusions: an inter-laboratory study by the BrainNet Europe consortium (2014) (23)
- The emerging clinical potential of circulating extracellular vesicles for non-invasive glioma diagnosis and disease monitoring (2019) (23)
- Inter-laboratory comparison of DNA preservation in archival paraffin-embedded human brain tissue from participating centres on four continents (2001) (21)
- Absence of the mitochondrial A7237T mutation in Parkinson's disease. (1995) (21)
- Nigral neurons are likely to die of a mechanism other than classical apoptosis in Parkinson's disease. (1999) (20)
- Defining Microglial States and Nomenclature: A Roadmap to 2030 (2022) (20)
- The expression of growth factor receptors during nerve regeneration. (1990) (20)
- The X‐Linked Dystonia‐Parkinsonism Syndrome (XDP): Clinical and Molecular Genetic Analysis (1992) (19)
- Light and electron microscopical immunocytochemistry of 5′-nucleotidase in rat cerebellum (2004) (19)
- Emergent Properties of Microglia (2014) (19)
- Evidence against a reliable staging system of α‐synuclein pathology in Parkinson's disease (2009) (19)
- Fine mapping of the human SCIDX1 locus at Xq12-13.1. (1993) (18)
- Microglial rod cells. (1994) (17)
- Twenty-first century brain banking: at the crossroads (2008) (16)
- Molecular basis and diagnosis of neurogenetic disorders (1994) (16)
- Dementia with Lewy bodies: disease concept and genetics (2003) (15)
- In vitro proliferation of axotomized rat facial nucleus‐derived activated microglia in an autocrine fashion (2006) (14)
- Striatal β-Amyloid Deposition in Parkinson Disease With Dementia. Authors' reply (2008) (14)
- The potential for genetically altered microglia to influence glioma treatment. (2013) (13)
- Perivascular location and phenotypic heterogeneity of microglial cells in the rat brain (1991) (12)
- Non‐Radioactive Direct Sequencing of PCR Products Amplified from Neuropathological Specimens (1993) (11)
- The 18-kDa Translocator Protein as a CNS Drug Target: Finding Our Way Through the Neuroinflammation Fog. (2018) (10)
- The α1-antichymotrypsin A-allele in German Parkinson disease patients (1999) (10)
- Bone marrow-derived microglia in pilocytic astrocytoma. (2011) (10)
- Cytokine Signalling at the Microglial Penta-Partite Synapse (2021) (9)
- Alois Alzheimer's case, Auguste D., did not carry the N141I mutation in PSEN2 characteristic of Alzheimer disease in Volga Germans. (2011) (9)
- Selective, high-contrast detection of syngeneic glioblastoma in vivo (2020) (9)
- Structural Plasticity in Lesioned Motoneurons (1988) (8)
- Synapses, Microglia, and Lipids in Alzheimer’s Disease (2022) (8)
- Global democratic consensus on neuropathological disease criteria (2002) (7)
- Wavelet analysis of gene expression (WAGE) (2004) (7)
- Parkinson disease: extranigral, multisystem, and {alpha}-synuclein "plus". (2009) (7)
- Genetics of neuroinflammation in Alzheimer disease (1999) (7)
- Nuclear Hormone and Orphan Receptors: Their Role in Neuronal Differentiation and Cytoprotection and in the Pathogenesis of Parkinson’s Disease (2003) (6)
- Microglioma in a child - a further case in support of the microglioma entity and distinction from histiocytic sarcoma. (2016) (6)
- Towards a molecular definition of microglia (2002) (6)
- Microglia, macrophages and the blood-brain barrier. (1993) (6)
- Up-regulation of matrix metallopeptidase 12 in motor neurons undergoing synaptic stripping (2014) (5)
- The role of astrocytes in facial nerve regeneration. (1994) (5)
- Association between ACT polymorphism and Alzheimer's disease. (1998) (5)
- A Free Community Approach to Classifying Disease (2004) (5)
- Microglia morphophysiological diversity and its implications for the CNS (2022) (5)
- What does apoptosis have to do with Parkinson's disease? (1999) (5)
- A Bifocal Classification and Fusion Network for Multimodal Image Analysis in Histopathology (2020) (4)
- PathoFusion: An Open-Source AI Framework for Recognition of Pathomorphological Features and Mapping of Immunohistochemical Data (2021) (4)
- ORIGINAL ARTICLE Rediscovery of the case described by Alois Alzheimer in 1911: historical, histological and molecular genetic analysis (1997) (3)
- Calcium–axonemal microtubuli interactions underlie mechanism(s) of primary cilia morphological changes (2018) (3)
- Transformation of bone marrow-derived macrophages into ramified microglia during autoimmune inflammation of the axotomized rat facial nucleus (1998) (3)
- Ground state depletion microscopy as a tool for studying microglia–synapse interactions (2020) (3)
- Development of the microglia literature. (1994) (3)
- Isolation of DNTR polymorphisms from yeast artificial chromosomes encompassing X chromosomal loci PGK1 and DXS56 (1992) (3)
- The 3rd German-Japanese Joint Workshop. Cell Death in the CNS: Molecules and Programs (1996) (2)
- [The apolipoprotein E gene and Alzheimer disease phenotype]. (1995) (2)
- Evidence for a Growing Involvement of Glia in Amyotrophic Lateral Sclerosis (2021) (2)
- Automated Machine-Learning Framework Integrating Histopathological and Radiological Information for Predicting IDH1 Mutation Status in Glioma (2021) (2)
- Depthwise Multiception Convolution for Reducing Network Parameters without Sacrificing Accuracy (2020) (2)
- Workshop 11: Microglia, Cell of the Brain Decade (1994) (2)
- A new approach to the genetic analysis of nervous system diseases: retrospective genotyping of archival brains. (1998) (2)
- Regulation of transferrin receptors and iron uptake in normal and injured nervous system. (1994) (2)
- The alpha1-antichymotrypsin A-allele in German Parkinson disease patients. (1999) (2)
- Antigen Presentation at the Blood-Brain Barrier: A Role for Astrocytes? (1993) (2)
- Sequence analysis of the MTCYB gene in Parkinson disease (2000) (2)
- Publication of microarray results (2003) (2)
- Expression profiling of the parkinsonian substantia nigra using microarrays (2004) (1)
- Driving innovation through collaboration: development of clinical annotation datasets for brain cancer biobanking. (2019) (1)
- Translating the cellular neuropathology of microglia into neuroimaging results (2004) (1)
- Four dinucleotide repeat polymorphisms at the D7S804 locus. (1993) (1)
- Microglia and gliomas may have a symbiotic relationship (2004) (1)
- Cellular Biology of the Experimental Peripheral Nerve Lesion (1990) (1)
- OLIGODENDROGLIOMAS: REPRODUCIBILITY OF GRADING PARAMETERS (1999) (1)
- An Open-Source AI Framework for the Analysis of Single Cells in Whole-Slide Images with a Note on CD276 in Glioblastoma (2022) (1)
- A European Board Examination in Neuropathology (2007) (1)
- Nonradioactive PCR sequencing using digoxigenin. (1996) (1)
- Glial Cells: Microglia during Normal Brain Aging (2009) (1)
- Glial activity and convergence of pathological pathways in Lewy Body parkinsonism (2004) (0)
- Contents Vol. 25, 2003 (2004) (0)
- ‘Neuroinflammation’ differs categorically from inflammation: transcriptomes of Alzheimer's disease, Parkinson's disease, schizophrenia and inflammatory diseases compared (2014) (0)
- 1-29-15 Sequence analysis of mitochondrial complex I genes in 23 Parkinson's disease patients (1997) (0)
- Microglial proliferation in the brain of chronic alcoholics with hepatic encephalopathy (2013) (0)
- Microglia and Brain Macrophages as Drivers of Glioma Progression (2022) (0)
- Subject Index Vol. 25, 2003 (2004) (0)
- Response from Authors (2008) (0)
- Developing the field of neurogenetics (2017) (0)
- The motoneuron and its microenvironment reacting to axonal lesions (1989) (0)
- ABSENCE OF APOE e4 ALLELE IN THE NEUROFIBRILLARY TANGLE SUBSET OF SENILE DEMENTIA (1997) (0)
- Poster Session 32: Degenerative Disease ll (1994) (0)
- XIIIth International Congress of Neuropathology 7-12 September 1997, Perth, Western Australia. (2006) (0)
- Online First publication (2001) (0)
- Alzheimerʼs disease, Parkinsonʼs disease and schizophrenia are not inflammatory diseases while inflammation is recognizable beyond organ borders (2015) (0)
- Glial Cells: Microglia (2019) (0)
- Towards an immunological definition of the blood-brain barrier: significane of major hisotcompatibity complex class II-positve perivascular cells (1992) (0)
- Tuberculosis In Vitro and In Vivo and Secretion in Central Nervous System Matrix Metalloproteinase Gene Expression Monocyte-Astrocyte Networks Regulate (2006) (0)
- 752 The apolipoprotein E e4 allele in Parkinson disease with and without Alzheimer lesions (1996) (0)
- Nonradioactive PCR sequencing using digoxigenin. (2003) (0)
- Correlation between mitochondrial respiratory chain and ubiquitin-proteasome gene expression in the human substantia nigra (2005) (0)
- Prof. Dr. med. Dr. med. h.c. Georg W. Kreutzberg (2020) (0)
- Glia and inflammation in the Parkinsonian substantia nigra (2009) (0)
- Forensic Neuropathology and Associated Neurology (2007) (0)
- Developing the field of neurogenetics (2017) (0)
- Workshop 5 (2009) (0)
- Calcium–axonemal microtubuli interactions underlie mechanism(s) of primary cilia morphological changes (2017) (0)
- Artificial intelligence techniques for neuropathological diagnostics and research. (2022) (0)
- To the Editor (1998) (0)
- Welcoming articles on genotype-dependent clinical features and diagnostics (2021) (0)
- Foreword (1993) (0)
- Microglia in gemistocytic astrocytomas. Commentary (2007) (0)
- Hippocampal CA2 Lewy pathology is associated with cholinergic degeneration in Parkinson’s disease with cognitive decline (2019) (0)
- Author Correction: Selective, high-contrast detection of syngeneic glioblastoma in vivo (2020) (0)
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What Schools Are Affiliated With Manuel Benedikt Graeber?
Manuel Benedikt Graeber is affiliated with the following schools: