Manuel Buchwald
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Canadian geneticist
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Genetics
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Molecular Biology
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Biology
Why Is Manuel Buchwald Influential?
(Suggest an Edit or Addition)According to Wikipedia, Manuel Buchwald, is a Canadian geneticist and academic. Born in Lima, Peru, he received a Bachelor of Arts degree summa cum laude in 1962 from Dartmouth College and a Ph.D. in 1967 from Brandeis University. He was a member of the Phi Beta Kappa Society.
Manuel Buchwald's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Erratum: Identification of the Cystic Fibrosis Gene: Genetic Analysis (1989) (2735)
- Identification of the cystic fibrosis gene: genetic analysis. (1989) (1687)
- Cloning of cDNAs for Fanconi's anaemia by functional complementation (1992) (547)
- Cystic fibrosis locus defined by a genetically linked polymorphic DNA marker. (1985) (482)
- Expression cloning of a cDNA for the major Fanconi anaemia gene, FAA (1996) (453)
- The Fanconi anaemia group G gene FANCG is identical with XRCC9 (1998) (357)
- In vivo cell-specific expression of the cystic fibrosis transmembrane conductance regulator (1991) (329)
- A polymorphic DNA marker linked to cystic fibrosis is located on chromosome 7 (1985) (317)
- Evidence for at least four Fanconi anaemia genes including FACC on chromosome 9 (1992) (308)
- The Fanconi anaemia gene FANCF encodes a novel protein with homology to ROM (2000) (298)
- Evidence for at least eight Fanconi anemia genes. (1997) (283)
- Inactivation of Fac in mice produces inducible chromosomal instability and reduced fertility reminiscent of Fanconi anaemia (1996) (263)
- Isolation of a cDNA representing the Fanconi anemia complementation group E gene. (2000) (262)
- Fanconi anemia group C protein prevents apoptosis in hematopoietic cells through redox regulation of GSTP1 (2001) (255)
- Susceptibility of Fanconi's anemia lymphoblasts to DNA-cross-linking and alkylating agents. (1982) (215)
- Multiple Inhibitory Cytokines Induce Deregulated Progenitor Growth and Apoptosis in Hematopoietic Cells From Fac−/− Mice (1998) (198)
- Cloning of cDNAs for Fanconi's anaemia by functional complementation (1992) (192)
- Loss of FancC Function Results in Decreased Hematopoietic Stem Cell Repopulating Ability (1999) (184)
- Classification of Fanconi anemia patients by complementation analysis: evidence for a fifth genetic subtype. (1995) (181)
- Lung disease in mice with cystic fibrosis. (1997) (172)
- Targeted disruption of exons 1 to 6 of the Fanconi Anemia group A gene leads to growth retardation, strain-specific microphthalmia, meiotic defects and primordial germ cell hypoplasia. (2003) (164)
- Phosphatase inhibitors activate normal and defective CFTR chloride channels. (1994) (155)
- Identification of two complementation groups in Fanconi anemia (1985) (148)
- Differential cellular expression of cystic fibrosis transmembrane regulator in human reproductive tissues. Clues for the infertility in patients with cystic fibrosis. (1994) (145)
- Fanconi anemia and novel strategies for therapy. (1994) (138)
- Cell-specific localization of CFTR mRNA shows developmentally regulated expression in human fetal tissues. (1993) (124)
- Erratum: Expression cloning of a cDNA for the major Fanconi anaemia gene, FAA (1996) (124)
- Optical properties of astaxanthin solutions and aggregates. (1968) (115)
- Isolation of ouabain-resistant human diploid fibroblasts. (1974) (109)
- The Tlx-2 homeobox gene is a downstream target of BMP signalling and is required for mouse mesoderm development. (1998) (106)
- A nonsense mutation and exon skipping in the Fanconi anaemia group C gene. (1993) (99)
- DNA marker haplotype association with pancreatic sufficiency in cystic fibrosis. (1989) (98)
- Properties of the crustacyanins and the yellow lobster shell pigment. (1968) (96)
- Defective hematopoiesis and hepatic steatosis in mice with combined deficiencies of the genes encoding Fancc and Cu/Zn superoxide dismutase. (2001) (94)
- Suppression of apoptosis in hematopoietic factor-dependent progenitor cell lines by expression of the FAC gene. (1996) (94)
- The morphogenesis of bacteriophage lambda. II. Identification of the principal structural proteins. (1970) (86)
- Bone marrow failure in the Fanconi anemia group C mouse model after DNA damage. (1998) (84)
- Stimulation of the cystic fibrosis transmembrane regulator expression by estrogen in vivo. (1993) (82)
- Complementation groups: one or more per gene? (1995) (82)
- Fanconi anemia C gene product plays a role in the fidelity of blunt DNA end-joining. (1998) (81)
- Molecular and Cellular Biology of Fanconi Anemia (1992) (80)
- Regional expression of CFTR in developing human respiratory tissues. (1994) (79)
- Development of an epithelium-specific expression cassette with human DNA regulatory elements for transgene expression in lung airways. (1997) (78)
- Phenotypic Abnormalities in Long-Term Surviving Cystic Fibrosis Mice (1996) (78)
- Fanconi anemia protein complex: mapping protein interactions in the yeast 2- and 3-hybrid systems. (2003) (78)
- Specific Activation of Smad 1 Signaling Pathways by the BMP 7 Type I Receptor , ALK 2 * (1998) (77)
- Is Fanconi anemia caused by a defect in the processing of DNA damage? (1998) (77)
- Cloning and analysis of the murine Fanconi anemia group C cDNA. (1993) (75)
- Regulation of CFTR expression and function during differentiation of intestinal epithelial cells. (1992) (71)
- The morphogenesis of bacteriophage lambda: I. Purification and characterization of λ heads and λ tails (1970) (66)
- Drug sensitivity spectra in Fanconi anemia lymphoblastoid cell lines of defined complementation groups. (1999) (63)
- Hematopoietic compartment of Fanconi anemia group C null mice contains fewer lineage-negative CD34+ primitive hematopoietic cells and shows reduced reconstruction ability. (1999) (61)
- The human homolog of insect-derived growth factor, CECR1, is a candidate gene for features of cat eye syndrome. (2000) (61)
- Human diploid fibroblast mutants with altered RNA polymerase II (1976) (56)
- Characterisation of the exon structure of the Fanconi anaemia group C gene by vectorette PCR. (1993) (56)
- FANCC, FANCE, and FANCD2 Form a Ternary Complex Essential to the Integrity of the Fanconi Anemia DNA Damage Response Pathway* (2005) (56)
- A functionally active retrovirus vector for gene therapy in Fanconi anemia group C (1994) (54)
- Characterization of regions functional in the nuclear localization of the Fanconi anemia group A protein. (1999) (53)
- A Leu554-to-Pro substitution completely abolishes the functional complementing activity of the Fanconi anemia (FACC) protein. (1993) (53)
- Estrogen-dependent expression of the cystic fibrosis transmembrane regulator gene in a novel uterine epithelial cell line. (1994) (52)
- Cystic fibrosis: beyond the gene to therapy. (1992) (51)
- Production of serum-blocking material by mutants of the left arm of the λ chromosome (1969) (50)
- Introduction and recovery of a selectable bacterial gene from the genome of mammalian cells (1982) (49)
- A functionally active retrovirus vector for gene therapy in Fanconi anemia group C. (1994) (45)
- Persistence of freely replicating SV40 recombinant molecules carrying a selectable marker in permissive simian cells (1982) (44)
- Targeting transgene expression to airway epithelia and submucosal glands, prominent sites of human CFTR expression. (2000) (43)
- Mutagenesis at the ouabain-resistance locus in human diploid fibroblasts. (1977) (42)
- Association of the TLX-2 Homeodomain and 14-3-3η Signaling Proteins* (1998) (41)
- Developmental expression of the Fac gene correlates with congenital defects in Fanconi anemia patients. (1996) (40)
- CONFORMATIONAL STUDIES ON SYNTHETIC POLY-α-AMINO ACIDS: THE HELICAL SENSE OF POLY-L-TRYPTOPHAN: OPTICAL ROTATORY DISPERSION STUDIES (1965) (36)
- Disease model: Fanconi anemia. (2002) (32)
- Mapping of DNA markers linked to the cystic fibrosis locus on the long arm of chromosome 7. (1987) (32)
- Transformed sweat gland and nasal epithelial cell lines from control and cystic fibrosis individuals. (1990) (30)
- Effect of cycloheximide and dexamethasone phosphate on hyaluronic acid synthesis and secretion in cultured human skin fibroblasts (1981) (29)
- Fanconi anemia revisited: Old ideas and new advances (1994) (26)
- Abnormal levels of 3':5'-cyclic AMP in isoproterenol-stimulated fibroblasts from patients with cystic fibrosis. (1976) (25)
- Regulation of the Fanconi Anemia Group C Protein through Proteolytic Modification* (2004) (25)
- Linkage between the loci for cystic fibrosis and paraoxonase (1986) (23)
- Induction of Fanconi anemia cellular phenotype in human 293 cells by overexpression of a mutant FAC allele. (1996) (23)
- Linkage of cystic fibrosis to the pro alpha 2(I) collagen gene, COL1A2, on chromosome 7. (1986) (23)
- Characterization of a simian virus 40-transformed Fanconi anemia fibroblast cell line. (1986) (22)
- Studies of gene transfer and reversion to mitomycin C resistance in Fanconi anemia cells. (1987) (20)
- Transgenic expression of CECR1 adenosine deaminase in mice results in abnormal development of heart and kidney (2005) (20)
- Expression of the Fanconi anemia gene FAC in human cell lines: lack of effect of oxygen tension. (1995) (20)
- Killing of fibroblasts by dexamethasone or dibutyryl adenosine 3',5'-monophosphate is not a valid test for cystic fibrosis. (1979) (20)
- Cloning and analysis of the mouse Fanconi anemia group A cDNA and an overlapping penta zinc finger cDNA. (2000) (19)
- Human cDNA clones that modify radiomimetic sensitivity of ataxia-telangiectasia (group A) cells (1995) (17)
- Mapping of the cystic fibrosis locus on chromosome 7. (1986) (17)
- Progress towards cloning the cystic fibrosis gene. (1988) (15)
- Two complementation groups of Fanconi's anemia differ in their phenotypic response to a DNA-crosslinking treatment (1987) (15)
- The search for the cystic fibrosis gene. (1989) (14)
- Characterization of the 5' region of the Fanconi anaemia group C (FACC) gene. (1995) (14)
- Use of cultured human cells for biochemical analysis. (1984) (13)
- Transgenic Expression in Mouse Lung Reveals Distinct Biological Roles for the Adenovirus Type 5 E1A 243- and 289-Amino-Acid Proteins (2002) (13)
- Plasma membrane lipids of human diploid fibroblasts from normal individuals and patients with cystic fibrosis. (1979) (13)
- Cloning and mutation analysis of ZFP276 as a candidate tumor suppressor in breast cancer (2003) (13)
- Complementation and Gene Transfer Studies in Fanconi Anemia (1989) (13)
- Short-term granulocyte colony-stimulating factor and erythropoietin treatment enhances hematopoiesis and survival in the mitomycin C-conditioned Fancc(-/-) mouse model, while long-term treatment is ineffective. (2002) (12)
- Regulation of expression of CFTR in human intestinal epithelial cells. (1991) (11)
- α -Amanitin-resistant Mutants of Mammalian Cells and the Regulation of RNA Polymerase II Activity (1976) (11)
- Alteration of a nuclease in Fanconi anemia. (1991) (11)
- Fanconi's anemia: what have we learned from the genes so far? (1998) (11)
- Induction of alkaline phosphatase in cultured human fibroblasts. Comparison of normal cells and those from patients with cystic fibrosis. (1979) (11)
- Production of serum-blocking material by mutants of the left arm of the lambda chromosome. (1969) (10)
- Recent advances in cystic fibrosis research. (1993) (10)
- Genetics and epithelial cell dysfunction in cystic fibrosis : proceedings of symposium held in Kimberly, Ontario, Canada, November 12-15, 1986 (1987) (10)
- In Vivo Potential Effects of Adenovirus Type 5 E1A and E1B on Lung Carcinogenesis and Lymphoproliferative Inflammation (2008) (9)
- Genetic complementation of radiation response by 3' untranslated regions (UTR) of RNA. (1996) (8)
- Title Identification of a polymorphic DNA marker pDL32B (D12S7) and its localization to the long arm of chromosome 12, region q14.3- qter (1985) (8)
- The Δ327 mutation in the fanconi anemia group C gene generates a novel transcript lacking the first two coding exons (1998) (7)
- Cystic fibrosis: from the gene to the dream. (1996) (7)
- Adenosine 3':5'-cyclic AMP in fibroblasts from patients with cystic fibrosis and its relationship to secretion. (1976) (6)
- Biochemical and genetic analysis of AMP deaminase deficiency in cultured mammalian cells. (1981) (6)
- Mammalian DNA-repair genes. (1993) (6)
- The morphogenesis of bacteriophage lambda. I. Purification and characterization of lambda heads and lambda tails. (1970) (6)
- HSC clinical trials controversy continues (1999) (6)
- The Fanconi anemia genes. (1998) (6)
- Culture of sweat gland epithelial cells from normal individuals and patients with cystic fibrosis (1985) (6)
- Microdissection and microcloning of the long arm of human chromosome 7 (2004) (5)
- Molecular characterization of Fanconi anaemia group C (FAC) gene polymorphisms. (1996) (5)
- Introduction andRecovery ofaSelectable Bacterial Gene fromtheGenomeofMammalian Cells (1982) (5)
- Isolation of plasma membranes from human skin fibroblasts (1977) (4)
- Aplastic Anemia: Genetic basis of Fanconi's anemia (1999) (4)
- Development and characterization of immortalized fibroblastoid cell lines from an FA(C) mouse model. (1998) (4)
- Characterization of a set of Chinese hamster ovary variant cell lines demonstrating differing sensitivity to mitomycin C. (1993) (4)
- EcoRI RFLP in the Fanconi anaemia complementation group C gene (FACC). (1993) (4)
- Aberrant expression and activity of histone deacetylases (HDACs) in lungs of patients with sporadic Idiopathic Pulmonary Fibrosis (IPF) (2012) (3)
- Reply to ‘Cellular function of the Fanconi anemia pathway’ (2001) (3)
- Cyclic nucleotides and cystic fibrosis. (1980) (3)
- A gene regulating the time dependence of α-l-fucosidase concentration is closely linked with the structural gene in man (2004) (3)
- Patient-based research in a tertiary pediatric centre: a pilot study of markers of scientific activity and productivity. (1997) (2)
- Expression of a mutant regulatory subunit of cAMP-dependent protein kinase in the Caco-2 human colonic carcinoma cell line. (1992) (2)
- Cloning of the bovine and rat Fanconi anemia group C cDNA (1997) (2)
- Utilization of cultured epithelial cells from the sweat gland in studies of the CF defect. (1987) (2)
- The FANCC Gene and Its Products (2006) (2)
- Correction of the spontaneous and DEB-induced chromosomal aberrations in Fanconi anemia cells of the FA(C) complementation group by the FACC gene. (1996) (2)
- RESPIRATORIO Lung Disease in Mice with Cystic Fibrosis (1997) (2)
- Identification of sequences of chromosome 7 that are expressed in sweat gland epithelial cells (1990) (1)
- Alexander F. Zakharov (1986) (1)
- Mapping of the murine and rat Facc genes and assessment of flexed-tail as a candidate mouse homolog of Fanconi anemia group C (2004) (1)
- THE TOXICITY OF DILAUDID INJECTED INTRAVENOUSLY INTO MICE (1941) (0)
- Isolating the cystic fibrosis gene and possibilities for treatment. (1990) (0)
- Assessment of the flexed-tail mouse as a possible model for Fanconi anemia: analysis of mitomycin C-induced micronuclei. (1996) (0)
- Targeted disruption of the murine Facc gene: Towards the establishment of a mouse model for Fanconi anemia (1994) (0)
- Analysis of the pattern of expression of the Fanconi anemia group C (Facc) gene during murine development (1994) (0)
- deficiencies of the genes encoding Fancc and Cu / Zn superoxide dismutase Defective hematopoiesis and hepatic steatosis in mice with combined (2001) (0)
- Subject Index Vol. 39, 1985 (1985) (0)
- Basic research in paediatrics: Does it exist? (2004) (0)
- Title Lung disease in mice with cystic fibrosis (1997) (0)
- Correction of both spontaneous and DEB-induced chromosome instability in Fanconi anemia FA-C cells by FACC cDNA (1994) (0)
- Identification andRegional Localization ofDNA Markers on Chromosome7fortheCloning oftheCystic Fibrosis Gene (1988) (0)
- Subject Index Vol. 41, 1986 (2004) (0)
- 16ALPHA‐METHYL REICHSTEIN S 21‐ACETAT AUS 16‐DEHYDRO‐PREGNENOLON ACETAT (1980) (0)
- Current status of the genetics of cystic fibrosis. (1987) (0)
- Cloning and characterization of the Fanconi anaemia complementation group F gene. (1999) (0)
- Lineages stable cell expressing the CFTR protein or a mutant of this protein, molecules of the selection tool having an effect on intracellular transport of these proteins (1996) (0)
- P27 09 WP – STUDIES OF A CHO CELL LINE RENDERED MMC RESISTANT BY TRANSFECTION OF HUMAN DNA (1991) (0)
- Advances in Human Genetics (1991) (0)
- Author Index / Subject Index Vol. 49, 1988 (1988) (0)
- HSC clinical trials controversy continues. Hospital for Sick Children. (1999) (0)
- Thiol Groups ofNormal HumanImmunoglobulin G (1974) (0)
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