Manuel Serrano

Q: What Schools Are Affiliated With Manuel Serrano

Manuel Serrano is affiliated with the following schools: University of California, Berkeley, Stanford University, Autonomous University of Madrid

Manuel Serrano's AcademicInfluence.com Rankings

Manuel Serrano

Computer Science

#3648

World Rank

#3833

Historical Rank

Database

#971

World Rank

#1022

Historical Rank

computer-science Degrees

Download Badge

Computer Science

Manuel Serrano's Degrees

PhD Computer Science Stanford University
Masters Computer Science University of California, Berkeley
Bachelors Computer Science University of California, Berkeley

Similar Degrees You Can Earn

Why Is Manuel Serrano Influential?

(Suggest an Edit or Addition)

(See a Problem?)

Manuel Serrano's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

The Hallmarks of Aging (2013) (9261)
Oncogenic ras Provokes Premature Cell Senescence Associated with Accumulation of p53 and p16INK4a (1997) (4862)
A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4 (1993) (3888)
Cellular senescence: from physiology to pathology (2014) (1723)
Role of the INK4a Locus in Tumor Suppression and Cell Mortality (1996) (1675)
Cellular Senescence in Cancer and Aging (2007) (1565)
Tumour biology: Senescence in premalignant tumours (2005) (1426)
A p16INK4a-insensitive CDK4 mutant targeted by cytolytic T lymphocytes in a human melanoma (1995) (1205)
A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity (2009) (1034)
Senescence in tumours: evidence from mice and humans (2010) (1020)
Cellular Senescence: Defining a Path Forward (2019) (1017)
Programmed Cell Senescence during Mammalian Embryonic Development (2013) (983)
The Ink4/Arf locus is a barrier for iPS cell reprogramming (2009) (973)
Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling. (1998) (948)
The common biology of cancer and ageing (2007) (911)
Sirt1 protects against high-fat diet-induced metabolic damage (2008) (902)
p19ARF links the tumour suppressor p53 to Ras (1998) (688)
Mutations and altered expression of p16INK4 in human cancer. (1994) (577)
Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer. (2010) (565)
Tumor induction by an endogenous K-ras oncogene is highly dependent on cellular context. (2003) (562)
'Super p53' mice exhibit enhanced DNA damage response, are tumor resistant and age normally (2002) (498)
Telomeres acquire embryonic stem cell characteristics in induced pluripotent stem cells. (2009) (486)
Delayed ageing through damage protection by the Arf/p53 pathway (2007) (463)
A new mouse model to explore the initiation, progression, and therapy of BRAFV600E-induced lung tumors. (2007) (463)
Putting the stress on senescence. (2001) (439)
Reprogramming in vivo produces teratomas and iPS cells with totipotency features (2013) (436)
Tissue damage and senescence provide critical signals for cellular reprogramming in vivo (2016) (432)
Telomerase Reverse Transcriptase Delays Aging in Cancer-Resistant Mice (2008) (426)
Pancreatitis-induced inflammation contributes to pancreatic cancer by inhibiting oncogene-induced senescence. (2011) (422)
The power and the promise of oncogene-induced senescence markers (2006) (414)
Inhibition of ras-induced proliferation and cellular transformation by p16INK4 (1995) (406)
GLP-1 Agonism Stimulates Brown Adipose Tissue Thermogenesis and Browning Through Hypothalamic AMPK (2014) (402)
p53: Guardian of the Genome and Policeman of the Oncogenes (2007) (398)
Tumor suppressors and oncogenes in cellular senescence☆ (2000) (381)
Tumor susceptibility of p21(Waf1/Cip1)-deficient mice. (2001) (371)
A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases (2008) (352)
The tumor suppressor protein p16INK4a. (1997) (309)
The atypical PKC-interacting protein p62 is an important mediator of RANK-activated osteoclastogenesis. (2004) (308)
Pten positively regulates brown adipose function, energy expenditure, and longevity. (2012) (303)
Mature-onset obesity and insulin resistance in mice deficient in the signaling adapter p62. (2006) (293)
Mutations associated with familial melanoma impair p16INK4 function (1995) (288)
Inhibition of the Phosphoinositide 3-Kinase Pathway Induces a Senescence-like Arrest Mediated by p27Kip1 * (2000) (286)
Salermide, a Sirtuin inhibitor with a strong cancer-specific proapoptotic effect (2009) (263)
SIRT1: recent lessons from mouse models (2010) (251)
Specific lipofuscin staining as a novel biomarker to detect replicative and stress-induced senescence. A method applicable in cryo-preserved and archival tissues (2012) (245)
SIRT1 contributes to telomere maintenance and augments global homologous recombination (2010) (231)
The cell cycle inhibitor p21 controls T-cell proliferation and sex-linked lupus development (2000) (223)
Murine fibroblasts lacking p21 undergo senescence and are resistant to transformation by oncogenic Ras (1999) (207)
Oncogenicity of the developmental transcription factor Sox9. (2012) (206)
Mutations in the p16INK4/MTS1/CDKN2, p15INK4B/MTS2, and p18 genes in primary and metastatic lung cancer. (1995) (203)
A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases (2008) (201)
Crystal structure of the complex of the cyclin D-dependent kinase Cdk6 bound to the cell-cycle inhibitor p19INK4d (1998) (199)
Oncogenic activity of Cdc6 through repression of the INK4/ARF locus (2006) (196)
Cloning and characterization of murine p16INK4a and p15INK4b genes. (1995) (195)
Deletion of the p16 and p15 genes in human bladder tumors. (1995) (194)
Cancer and ageing: convergent and divergent mechanisms (2007) (186)
Identification and characterization of Cardiac Glycosides as senolytic compounds (2019) (177)
G6PD protects from oxidative damage and improves healthspan in mice (2016) (172)
PTEN in cancer, metabolism, and aging (2013) (170)
A versatile drug delivery system targeting senescent cells (2018) (170)
Histone macroH2A isoforms predict the risk of lung cancer recurrence (2009) (169)
Robust, universal biomarker assay to detect senescent cells in biological specimens (2016) (159)
Sirtuin 1 regulation of developmental genes during differentiation of stem cells (2010) (157)
Combined inhibition of DDR1 and Notch signaling is a therapeutic strategy for KRAS-driven lung adenocarcinoma (2016) (157)
Mechanistic principles of chromatin remodeling guided by siRNAs and miRNAs (2008) (148)
Increased gene dosage of Ink4a/Arf results in cancer resistance and normal aging. (2004) (141)
Polycomb Mediated Epigenetic Silencing and Replication Timing at the INK4a/ARF Locus during Senescence (2009) (140)
Cellular senescence limits regenerative capacity and allograft survival. (2012) (130)
The Arf/p53 pathway in cancer and aging. (2008) (129)
Induction of p53-dependent senescence by the MDM2 antagonist nutlin-3a in mouse cells of fibroblast origin. (2007) (127)
TGFβ inhibition restores a regenerative response in acute liver injury by suppressing paracrine senescence (2018) (127)
The downregulation of the pro‐apoptotic protein Par‐4 is critical for Ras‐induced survival and tumor progression (1999) (124)
Tumour biology: Policing of oncogene activity by p53 (2006) (123)
p27Kip1 Directly Represses Sox2 during Embryonic Stem Cell Differentiation (2012) (123)
Senescence promotes in vivo reprogramming through p16INK 4a and IL‐6 (2017) (122)
The INK4a/ARF locus in murine tumorigenesis. (2000) (120)
miR-33-mediated downregulation of p53 controls hematopoietic stem cell self-renewal (2010) (111)
p53-dependent association between cyclin G and the B' subunit of protein phosphatase 2A (1996) (111)
Therapeutic effect of γ-secretase inhibition in KrasG12V-driven non-small cell lung carcinoma by derepression of DUSP1 and inhibition of ERK. (2012) (108)
The stress kinase MKK7 couples oncogenic stress to p53 stability and tumor suppression (2011) (108)
PTEN recruitment controls synaptic and cognitive function in Alzheimer's models (2016) (107)
Galacto‐conjugation of Navitoclax as an efficient strategy to increase senolytic specificity and reduce platelet toxicity (2020) (105)
Tumour‐suppression activity of the proapoptotic regulator Par4 (2005) (105)
An OFF-ON Two-Photon Fluorescent Probe for Tracking Cell Senescence in Vivo. (2017) (104)
Increased p53 activity does not accelerate telomere‐driven ageing (2006) (101)
Anti‐aging activity of the Ink4/Arf locus (2009) (100)
SIRT1 controls liver regeneration by regulating bile acid metabolism through farnesoid X receptor and mammalian target of rapamycin signaling (2014) (99)
WNT16B is a new marker of cellular senescence that regulates p53 activity and the phosphoinositide 3-kinase/AKT pathway. (2009) (96)
p19(ARF) deficiency reduces macrophage and vascular smooth muscle cell apoptosis and aggravates atherosclerosis. (2010) (96)
The PTEN/NRF2 axis promotes human carcinogenesis. (2014) (95)
Mutational effects on the p16INK4a tumor suppressor protein. (1995) (95)
Inactivation of the candidate tumor suppressor par-4 in endometrial cancer. (2007) (95)
Hallmarks of aging: An expanding universe (2022) (94)
PTEN mediates Notch-dependent stalk cell arrest in angiogenesis (2015) (88)
EMT and induction of miR-21 mediate metastasis development in Trp53-deficient tumours (2012) (87)
Par‐4 inhibits Akt and suppresses Ras‐induced lung tumorigenesis (2008) (86)
NOTCH pathway inactivation promotes bladder cancer progression. (2015) (86)
Cold-Inducible RNA-Binding Protein Bypasses Replicative Senescence in Primary Cells through Extracellular Signal-Regulated Kinase 1 and 2 Activation (2009) (81)
Activation of cyclin D1-kinase in murine fibroblasts lacking both p21Cip1 and p27Kip1 (2002) (81)
Limiting replication stress during somatic cell reprogramming reduces genomic instability in induced pluripotent stem cells (2015) (80)
Tumorigenic activity of p21Waf1/Cip1 in thymic lymphoma (2006) (80)
Pharmacological inhibition of PI3K reduces adiposity and metabolic syndrome in obese mice and rhesus monkeys. (2015) (77)
Resistance to viral infection of super p53 mice (2005) (77)
Induction of senescence by oncogenic Ras. (2001) (76)
SIRT1 promotes thyroid carcinogenesis driven by PTEN deficiency (2013) (76)
The absence of p53 is critical for the induction of apoptosis by 5-aza-2′-deoxycytidine (2004) (76)
Inactivation of the cyclin-dependent kinase inhibitor p15INK4b by deletion and de novo methylation with independence of p16INK4a alterations in murine primary T-cell lymphomas (1997) (75)
The Senescent Side of Tumor Suppression (2005) (74)
SIRT1 enhances glucose tolerance by potentiating brown adipose tissue function (2014) (71)
Dietary restriction: standing up for sirtuins. (2010) (70)
Regulation of the tumor suppressor PTEN by SUMO (2012) (69)
Epigenetic regulation of Nanog expression by Ezh2 in pluripotent stem cells (2011) (67)
Regulation of macrophage activation and septic shock susceptibility via p21(WAF1/CIP1) (2009) (66)
Partial Loss of Rpl11 in Adult Mice Recapitulates Diamond-Blackfan Anemia and Promotes Lymphomagenesis. (2015) (66)
Genetic inactivation of Par4 results in hyperactivation of NF‐κB and impairment of JNK and p38 (2003) (65)
A Stat6/Pten Axis Links Regulatory T Cells with Adipose Tissue Function. (2017) (64)
Nephrin deficiency activates NF-kappaB and promotes glomerular injury. (2009) (63)
A novel nucleoprotein complex at a replication origin. (1990) (62)
The chemistry of senescence (2019) (61)
Crosstalk between PKCζ and the IL4/Stat6 pathway during T‐cell‐mediated hepatitis (2004) (60)
Identification of a candidate tumor-suppressor gene specifically activated during Ras-induced senescence. (2002) (60)
Depletion of ribosomal protein L37 occurs in response to DNA damage and activates p53 through the L11/MDM2 pathway (2010) (59)
Sirtuin-1 regulates acinar-to-ductal metaplasia and supports cancer cell viability in pancreatic cancer. (2013) (59)
Limited Role of Murine ATM in Oncogene-Induced Senescence and p53-Dependent Tumor Suppression (2009) (57)
Naked mole rats can undergo developmental, oncogene-induced and DNA damage-induced cellular senescence (2018) (57)
Growth Inhibition by the Tumor Suppressor p33ING1 in Immortalized and Primary Cells: Involvement of Two Silencing Domains and Effect of Ras (2005) (56)
Antiviral action of the tumor suppressor ARF (2006) (56)
A Unified Nomenclature and Amino Acid Numbering for Human PTEN (2014) (55)
Genome-wide CTCF distribution in vertebrates defines equivalent sites that aid the identification of disease-associated genes (2011) (55)
Genome-wide CTCF distribution in vertebrates defines equivalent sites that aid the identification of disease-associated genes (2011) (55)
Ghrelin requires p53 to stimulate lipid storage in fat and liver. (2013) (55)
Increased dosage of tumor suppressors limits the tumorigenicity of iPS cells without affecting their pluripotency (2012) (55)
The ink4a/arf Tumor Suppressors Cooperate with p21 cip1/waf in the Processes of Mouse Epidermal Differentiation, Senescence, and Carcinogenesis* (2001) (54)
Resveratrol treatment restores peripheral insulin sensitivity in diabetic mice in a sirt1-independent manner. (2015) (54)
SIRT1 stabilizes PML promoting its sumoylation (2011) (54)
A High-Throughput Loss-of-Function Screening Identifies Novel p53 Regulators (2006) (53)
SIRT1 Undergoes Alternative Splicing in a Novel Auto-Regulatory Loop with p53 (2010) (53)
Restoration of energy homeostasis by SIRT6 extends healthy lifespan (2021) (53)
Genomic instability in iPS: time for a break (2011) (52)
Regulation of mature T lymphocyte proliferation and differentiation by Par‐4 (2003) (52)
Free [NADH]/[NAD(+)] regulates sirtuin expression. (2011) (50)
A New Mechanism of Inactivation of the INK4/ARF Locus (2006) (49)
Tumor Suppressor p53 Mediates Apoptotic Cell Death Triggered by Cyclosporin A* (2002) (48)
Lysosomal trapping of palbociclib and its functional implications (2019) (48)
Signals at the bacteriophage phi 29 DNA replication origins required for protein p6 binding and activity. (1989) (48)
p73beta-Mediated apoptosis requires p57kip2 induction and IEX-1 inhibition. (2005) (47)
Simultaneous inactivation of Par-4 and PTEN in vivo leads to synergistic NF-κB activation and invasive prostate carcinoma (2009) (47)
Increased p53 gene dosage reduces neointimal thickening induced by mechanical injury but has no effect on native atherosclerosis. (2007) (47)
In Vivo Inhibition of c-MYC in Myeloid Cells Impairs Tumor-Associated Macrophage Maturation and Pro-Tumoral Activities (2012) (46)
Epigenetic induction of the Ink4a/Arf locus prevents Schwann cell overproliferation during nerve regeneration and after tumorigenic challenge. (2013) (46)
Lineage-restricted function of the pluripotency factor NANOG in stratified epithelia (2014) (46)
Preclinical antitumor efficacy of senescence-inducing chemotherapy combined with a nanoSenolytic. (2020) (45)
Ribosomal stress induces L11- and p53-dependent apoptosis in mouse pluripotent stem cells (2012) (44)
Inactivation of imprinted genes induced by cellular stress and tumorigenesis. (2005) (44)
Cancer regression by senescence. (2007) (43)
Δ133p53 represses p53-inducible senescence genes and enhances the generation of human induced pluripotent stem cells (2017) (43)
Cloning and characterization of murine p16(INK4a) and p15(INK4b) genes (1995) (43)
Reprogramming activity of NANOGP8, a NANOG family member widely expressed in cancer (2014) (42)
Genomic profiling of circulating plasma RNA for the analysis of cancer. (2007) (40)
Acetylation is indispensable for p53 antiviral activity (2011) (40)
Genetic dissection of the role of p21Cip1/Waf1 in p53-mediated tumour suppression (2007) (40)
Impact papers on aging in 2009 (2010) (40)
Shifting senescence into quiescence by turning up p53 (2010) (40)
Activation of ARF by oncogenic stress in mouse fibroblasts is independent of E2F1 and E2F2 (2002) (39)
Suppression of growth in vitro and tumorigenicity in vivo of human carcinoma cell lines by transfected p16INK4 (1996) (39)
NSD2 contributes to oncogenic RAS-driven transcription in lung cancer cells through long-range epigenetic activation (2016) (39)
The pluripotency factor NANOG promotes the formation of squamous cell carcinomas (2015) (38)
Different cooperating effect of p21 or p27 deficiency in combination with INK4a/ARF deletion in mice (2004) (37)
A functional link between the tumour suppressors ARF and p33ING1 (2006) (37)
Superhelical path of the DNA in the nucleoprotein complex that activates the initiation of phage phi 29 DNA replication. (1993) (37)
Specific Contribution of p19ARF to Nitric Oxide-Dependent Apoptosis1 (2006) (37)
Interaction of the bacteriophage phi 29 protein p6 with double-stranded DNA. (1988) (37)
Rplp1 bypasses replicative senescence and contributes to transformation. (2009) (36)
AAV vector-mediated in vivo reprogramming into pluripotency (2018) (35)
Regulation of the INK4a/ARF Locus by Histone Deacetylase Inhibitors* (2005) (35)
Multimeric complexes formed by DNA-binding proteins of low sequence specificity. (1993) (34)
Stabilization of p21 by mTORC1/4E-BP1 predicts clinical outcome of head and neck cancers (2016) (34)
Increased gene dosage of Ink4/Arf and p53 delays age-associated central nervous system functional decline (2015) (34)
Common Telomere Changes during In Vivo Reprogramming and Early Stages of Tumorigenesis (2017) (34)
Mouse p73 gene maps to the distal part of chromosome 4 and might be involved in the progression of gamma-radiation-induced T-cell lymphomas. (1999) (33)
Impact of Sirt1 on mammalian aging (2010) (33)
Cancer: A lower bar for senescence (2010) (33)
In Vivo Reprogramming Ameliorates Aging Features in Dentate Gyrus Cells and Improves Memory in Mice (2020) (33)
Dissecting the role of mTOR complexes in cellular senescence (2012) (32)
A minimally invasive assay for individual assessment of the ATM/CHEK2/p53 pathway activity (2011) (32)
p16INK4 mutations and altered expression in human tumors and cell lines. (1994) (28)
Activation of Replication Origins in φ29-related Phages Requires the Recognition of Initiation Proteins to Specific Nucleoprotein Complexes* (1996) (28)
Protein-nucleic acid interactions in bacteriophage phi 29 DNA replication. (1995) (28)
Transcription activation at a distance by phage phi 29 protein p4. Effect of bent and non-bent intervening DNA sequences. (1991) (28)
Sirt4: the glutamine gatekeeper. (2013) (28)
MSK2 Inhibits p53 Activity in the Absence of Stress (2009) (28)
Activation of sirtuin 1 as therapy for the peroxisomal disease adrenoleukodystrophy (2015) (28)
Global hyperactivation of enhancers stabilizes human and mouse naive pluripotency through inhibition of CDK8/19 Mediator kinases (2020) (27)
Senescence helps regeneration. (2014) (27)
Increased dosage of Ink4/Arf protects against glucose intolerance and insulin resistance associated with aging (2013) (27)
Analysis of p16INK4a and its interaction with CDK4. (1996) (27)
Unraveling the links between cancer and aging. (2016) (27)
Phage Ø29 protein p6: A viral histone-like protein (1994) (27)
Association of rat p15INK4B/p16INK4 deletions with monosomy 5 in kidney epithelial cell lines but not primary renal tumors. (1995) (27)
Ing1 Mediates p53 Accumulation and Chromatin Modification in Response to Oncogenic Stress* (2007) (26)
Cancer: Final act of senescence (2011) (25)
Non-genotoxic activation of p53 through the RPL11-dependent ribosomal stress pathway. (2014) (25)
A new mouse model to explore the initiation, progression, and therapy (2007) (25)
Multi‐omic rejuvenation of naturally aged tissues by a single cycle of transient reprogramming (2022) (24)
Troponin-I enhances and is required for oncogenic overgrowth (2016) (24)
Adult Sox2+ stem cell exhaustion in mice results in cellular senescence and premature aging (2018) (24)
Targeting senescence (2018) (23)
The RNA Polymerase II Factor RPAP1 Is Critical for Mediator-Driven Transcription and Cell Identity (2018) (21)
G6PD overexpression protects from oxidative stress and age‐related hearing loss (2020) (20)
Effect of presenilins in the apoptosis of thymocytes and homeostasis of CD8+ T cells. (2007) (20)
PI3Kɑ inhibition reduces obesity in mice (2016) (19)
The TRIP from ULF to ARF. (2010) (19)
The p21Cip1 protein, a cyclin inhibitor, regulates the levels and the intracellular localization of CDC25A in mice regenerating livers (2002) (19)
Limited role of Sirt1 in cancer protection by dietary restriction (2011) (17)
Apoptosis, G1 Phase Stall, and Premature Differentiation Account for Low Chimeric Competence of Human and Rhesus Monkey Naive Pluripotent Stem Cells (2020) (17)
Cellular Senescence in Lung Fibrosis (2021) (17)
Cellular senescence is immunogenic and promotes anti-tumor immunity. (2022) (17)
Engineering Cancer Resistance in Mice (2003) (17)
A strategy to study tyrosinase transgenes in mouse melanocytes (2005) (17)
Characterization of a DNA binding protein of bacteriophage PRD1 involved in DNA replication. (1990) (17)
Exome sequencing of three cases of familial exceptional longevity (2014) (17)
Sirt1 protects from K‐Ras‐driven lung carcinogenesis (2018) (16)
Transcriptional regulation of Sox2 by the retinoblastoma family of pocket proteins (2014) (16)
A Two-Photon Probe Based on Naphthalimide-Styrene Fluorophore for the In Vivo Tracking of Cellular Senescence (2021) (16)
Increased gene dosage of the Ink4/Arf locus does not attenuate atherosclerosis development in hypercholesterolaemic mice. (2012) (15)
Analysis of the candidate tumor suppressor Ris-1 in primary human breast carcinomas. (2006) (14)
Specific contribution of p19ARF to nitric oxide-dependent apoptosis (2007) (14)
erratum: Crystal structure of the complex of the cyclin D-dependent kinase Cdk6 bound to the cell-cycle inhibitor p19INK4d (1998) (14)
The Arf / p 53 Pathway in Cancer and Aging (2008) (14)
Senescence and Cancer: In the Name of Immunosuppression. (2016) (13)
DNA conformational change induced by the bacteriophage phi 29 connector. (1992) (13)
RANK links senescence to stemness in the mammary epithelia, delaying tumor onset but increasing tumor aggressiveness (2021) (13)
Normal Proliferation and Tumorigenesis but Impaired Pancreatic Function in Mice Lacking the Cell Cycle Regulator Sei1 (2010) (12)
p21Cip1 plays a critical role in the physiological adaptation to fasting through activation of PPARα (2016) (12)
SHP2: a new target for pro‐senescence cancer therapies (2015) (11)
Proliferation: the cell cycle. (2003) (11)
Transient exposure to miR‐203 enhances the differentiation capacity of established pluripotent stem cells (2020) (11)
Impact papers on aging in 2009 - eScholarship (2010) (11)
IFNα 2b induces apoptosis and proteasome-mediated degradation of p27Kip1 in a human lung cancer cell line (2001) (11)
to constitutive MEK / MAPK mitogenic signaling Premature senescence involving p 53 and p 16 is activated in response (1998) (10)
Dissection of two routes to naïve pluripotency using different kinase inhibitors (2021) (10)
“Super p53” Mice Display Retinal Astroglial Changes (2013) (10)
Diamond Blackfan anemia is mediated by hyperactive Nemo-like kinase (2020) (10)
p53 Modulates the Fate of Cardiac Progenitor Cells Ex Vivo and in the Diabetic Heart In Vivo (2017) (9)
Ageing: Tools to eliminate senescent cells (2017) (9)
The InflammTORy Powers of Senescence. (2015) (9)
Transcription activation at a distance by phage ø29 protein p4 (1991) (9)
Imaging Cancer in Mice by PET, CT, and Combined PET‐CT (2011) (8)
MED15 prion-like domain forms a coiled-coil responsible for its amyloid conversion and propagation (2021) (8)
Activation of p21 limits acute lung injury and induces early senescence after acid aspiration and mechanical ventilation (2020) (8)
Transcription regulation in Bacillus subtilis phage Φ29 (1991) (8)
Salermide, a Sirtuin inhibitor with a strong cancer-specific proapoptotic effect (2009) (8)
ArticleThe Atypical PKC-Interacting Protein p 62 Is an Important Mediator of RANK-Activated Osteoclastogenesis (2004) (7)
Notching up a new therapeutic strategy for Non-Small Cell Lung Carcinoma (NSCLC) (2012) (7)
[Biochemical characterization of the optic nerve in mice overexpressing the P53 gen. Oxidative stress assays]. (2008) (7)
Networks of tumor suppressors (2000) (6)
Dual-Specificity Phosphatase 1 (DUSP1) Has a Central Role in Redox Homeostasis and Inflammation in the Mouse Cochlea (2021) (6)
Glucose 6‐P dehydrogenase delays the onset of frailty by protecting against muscle damage (2021) (6)
CtIP-Specific Roles during Cell Reprogramming Have Long-Term Consequences in the Survival and Fitness of Induced Pluripotent Stem Cells (2017) (6)
Mitochondrial Damage Induces Senescence with a Twisted Arm. (2016) (6)
Natural killer cells act as an extrinsic barrier for in vivo reprogramming (2022) (6)
Metformin and reprogramming into iPSCs (2012) (6)
Identification of the gene immediately downstream of the murine INK4a/ARF locus (2001) (6)
Induction of Lysosome Membrane Permeabilization as a Therapeutic Strategy to Target Pancreatic Cancer Stem Cells (2020) (5)
Glaucoma Genetics – Regulation of Cell Surviving and Death in the Retina (2011) (5)
Abstract 922: Delta133p53 represses p53-inducible senescence genes and enhances the generation of human induced pluripotent stem cells (2017) (5)
Understanding Aging (2017) (5)
Nephrin Deficiency Activates NF- B and Promotes Glomerular Injury (2009) (5)
Normal cellular senescence and cancer susceptibility in mice genetically deficient in Ras-induced senescence-1 (Ris1) (2007) (4)
Fatty acids homeostasis during fasting predicts protection from chemotherapy toxicity (2022) (4)
IFNalpha 2b induces apoptosis and proteasome-mediated degradation of p27Kip1 in a human lung cancer cell line. (2001) (4)
SOX9 Triggers Different Epithelial to Mesenchymal Transition States to Promote Pancreatic Cancer Progression (2022) (4)
Induction of senescence renders cancer cells highly immunogenic (2022) (4)
Protein-primed replication of bacteriophage phi 29 DNA. (1988) (4)
Meeting Report: Aging Research and Drug Discovery (2022) (4)
Analysis of the advantages of cis reporters in optimized FACS‐Gal (2017) (4)
Bladder cancer and the Notch pathway (2015) (4)
p73 hhh -Mediated Apoptosis Requires p57 kip2 Induction and IEX-1 Inhibition (2005) (3)
Phage phi 29 protein p6: a viral histone-like protein. (1994) (3)
Iron accumulation drives fibrosis, senescence, and the senescence-associated secretory phenotype (2022) (3)
Nuclear reprogramming and the cancer genome (2013) (2)
The trophectoderm acts as a niche for the inner cell mass through C/EBPα-regulated IL-6 signaling (2022) (2)
The lysosomal proteome of senescent cells contributes to the senescence secretome (2022) (2)
The efficacy of chemotherapy is limited by intratumoural senescent cells that persist through the upregulation of PD-L2 (2022) (2)
Advances in Brief Mutations in the p 16 @ ' @ 4 / MTS 1 / CDKN 2 , p 15 @ 4 B / MTS 2 , and p 18 Genes in Primary and Metastatic Lung Cancer ' (2006) (2)
Manipulating the Mediator complex to induce naïve pluripotency (2020) (2)
DNA structure in the nucleoprotein complex that activates replication of phage phi 29. (1994) (2)
Induced Pluripotency: Generation of iPS Cells from Mouse Embryonic Fibroblasts (2011) (2)
Induction of Balbiani ring puffing changes by sugars and alcohols in Chironomus thummi. (1990) (2)
Senescence-associated morphological profiles (SAMPs): an image-based phenotypic profiling method for evaluating the inter and intra model heterogeneity of senescence (2022) (2)
Conservation of Aging and Cancer Epigenetic Signatures across Human and Mouse (2021) (2)
Cancer Cell Viability in Pancreatic Cancer Sirtuin-1 Regulates Acinar-to-Ductal Metaplasia and Supports (2013) (1)
G6PD Overexpression Protects Mice Against Associated Oxidative Stress and Delays the Occurrence of Frailty (2016) (1)
The RNA Polymerase II Fa ctor RPAP 1 Is Critical for Mediator-Driven Transcription and Cell Identity Graphical (2018) (1)
Targeting Mitochondria to Control Ageing and Senescence (2023) (1)
[The cell cycle and gene p53. An approach to molecular ophthalmology]. (2010) (1)
Retraction: Oncogenic activity of Cdc6 through repression of the INK4/ARF locus (2017) (1)
Cellular senescence limits acute lung injury induced by mechanical ventilation (2020) (1)
Antiviral action of the tumor suppressor ARF Marı́a (2013) (1)
The cell cycle and gene p53. An approach to molecular ophthalmology (2010) (1)
Tumor and Stem Cell Biology Oncogenicity of the Developmental Transcription Factor Sox 9 (2012) (1)
Deciphering the roadmap of in vivo reprogramming toward pluripotency (2022) (1)
A novel microRNA-based strategy to expand the differentiation potency of stem cells (2019) (0)
G6PD overexpression protects from oxidative stress and ameliorates ARHL progression (2019) (0)
Association of Rat pl 5 INK 4 Blpl 6 INK 4 Deletions with Monosomy 5 in Kidney Epithelial Cell Lines but not Primary Renal Tumors 1 (2006) (0)
Bmi1 puSHHes reprogramming (2011) (0)
MED15 prion-like domain forms a coiled-coil responsible for its amyloid conversion and propagation (2021) (0)
A novel redox cycle diverts cells from oncogene-induced senescence into cancer. (2021) (0)
A NIR fluorescent probe for the detection of renal damage based on overrepresentation of alanine aminopeptidase enzyme. (2023) (0)
Faculty Opinions recommendation of p63 deficiency activates a program of cellular senescence and leads to accelerated aging. (2005) (0)
Impact papers on aging in 2009 Citation (2022) (0)
3182 – PHARMACOLOGICAL INHIBITION OF NEMO-LIKE KINASE RESCUES MTOR-MEDIATED TRANSLATION AND ERYTHROPOIESIS IN PRE-CLINICAL MODELS OF DIAMOND BLACKFAN ANEMIA (2019) (0)
erratum Crystal structureof thecomplex of thecyclinD-dependent kinaseCdk 6 bound to the cell-cycle inhibitor p 19 INK 4 d (0)
Mechanisms Underlying p53 Genetic Regulation of Vascular Endothelial Growth Factor (VEGF) and Brain Derived Neurotrophic Factor (BDNF) in Mice Retina (2010) (0)
P16(Ink4) - an Specific Inhibitor of the Cdk4/Cyclin-D Kinase (1994) (0)
Pharmacological Inhibition of Nlk (Nemo-like Kinase) Rescues Erythropoietic Defects in Pre-Clinical Models of Diamond Blackfan Anemia (2018) (0)
The role of inflammation mediated by MKP1 in age-related hearing loss (2017) (0)
Metformin Upregulates Mir-26a to Improve Erythropoiesis in Preclinical Models of Diamond Blackfan Anemia through Suppression of Nlk Expression (2020) (0)
Cancer Cell Previews Sirt 4 : The Glutamine Gatekeeper (2013) (0)
Session 3: Cancer Prevention (2004) (0)
Pharmacological Inhibition of Nemo-like Kinase Rescues mTOR-Mediated Translation and Primes Progenitors for Leucine-Stimulated Erythroid Expansion in Pre-Clinical Models of Diamond Blackfan Anemia (2019) (0)
Oxide-Dependent Apoptosis to NitricARFSpecific Contribution of p 19 Boscá and Sonsoles Hortelano (2006) (0)
AAV vector-mediated in vivo reprogramming into pluripotency (2018) (0)
Stem Cell Repor ts The trophectoderm acts as a niche for the inner cell mass through C/EBP a -regulated IL-6 signaling (2022) (0)
Pseudoalignment tools as an efficient alternative to detect repeated transposable elements in scRNAseq data (2022) (0)
The cell cycle and why is it important for oncology (2000) (0)
Transcription regulation in Bacillus subtilis phage phi 29. (1991) (0)
Abstract SY11-03: Sirt1 transgenic and cancer models (2011) (0)
Characterization ofa DNAbinding protein of bacteriophage PRD1involved inDNAreplication (1990) (0)
Anti-obesity effect in mice and monkeys of partial inhibition of PI3K[alpha] (2018) (0)
Recent insights into the crosstalk between senescent cells and CD8 T lymphocytes (2023) (0)
Prognostic significance of mediastinal node level invasion in non small cell lung cancer (1991) (0)
Effect of presenilins in the apoptosis of thymocytes and homeostasis of CD8 (cid:1) T cells (2007) (0)
Faculty Opinions recommendation of Selective evolution of stromal mesenchyme with p53 loss in response to epithelial tumorigenesis. (2005) (0)
Stability of Imprinting and Differentiation Capacity in Naïve Human Cells Induced by Chemical Inhibition of CDK8 and CDK19 (2021) (0)
Keep calm and transcribe on: chromatin changes with age, but transcription can learn to live with it (2022) (0)
Intercellular Signaling in Cardiovascular Development and Disease Group, Centro Nacional de Investigaciones Cardiovasculares, (2015) (0)
Diamond Blackfan anemia is mediated by hyperactive Nemo-like kinase (2020) (0)
Abstract B45: A cell-based screening to identify nucleolar disruptors in cancer cells (2013) (0)
Defective Slc7a7 transport reduces erythropoietin compromising erythropoiesis and iron homeostasis (2021) (0)
Author Correction: Identification and characterization of Cardiac Glycosides as senolytic compounds (2020) (0)
Oxide-Dependent Apoptosis to Nitric ARF Specific Contribution of p19 (2011) (0)
The Serine Threonine Kinase Inhibitor Ots-167 Improves Erythropoiesis through Suppression of Nlk Activity in Diamond Blackfan Anemia Models (2021) (0)
Senescence as a therapeutic target (2022) (0)
Cellular senescence enhances adaptive anticancer immunosurveillance (2022) (0)
Is a New Marker of Cellular Senescence That Regulates p 53 Activity and the Phosphoinositide 3-Kinase / AKT Pathway (2009) (0)
A humanized animal model of pulmonary fibrosis based on cellular senescence (2020) (0)
Author Correction: The stress kinase MKK7 couples oncogenic stress to p53 stability and tumor suppression. (2023) (0)
Primate naïve pluripotent stem cells stall in the G1 phase of the cell cycle and differentiate prematurely during embryo colonization (2020) (0)
Targeting senescence (2018) (0)
706 Altered Expression of Sirtuin-1 or Its Inhibitor Deleted in Breast Cancer-1 Affects Premalignant Changes in Mouse Exocrine Tissue and Growth of Human Pancreatic Ductal Adenocarcinoma Cells (2012) (0)
300. AAV Vector-Mediated In Vivo Reprogramming of Various Cell Types in Adult Mice (2015) (0)
SIRTI is not required for the beneficial effects of resveratrol treatment on insulin sensitivity in diabetic mice (2014) (0)
Pre-cancer: From diagnosis to intervention opportunities. (2023) (0)
Correction: Ing1 mediates p53 accumulation and chromatin modification in response to oncogenic stress (2021) (0)
Overexpression of G6PD as a model of robustness (2018) (0)
The role of p27kip1 in the development, differentiation and maturation of mesencephalic dopaminergic neurons. (2018) (0)
Abstract IA09: A drug delivery method selective for senescent cells (2016) (0)
P19INK4D/CDK6 COMPLEX (1999) (0)
Young and Lean: Elimination of Senescent Cells Boosts Adaptive Thermogenesis. (2017) (0)
Tumor and Stem Cell Biology Oncogenicity of the Developmental Transcription Factor Sox9 (2012) (0)
Recent progress on the mechanisms of aging and its medical applications (2019) (0)
Faculty Opinions recommendation of Temporal dissection of p53 function in vitro and in vivo. (2005) (0)
Have you seen ? SHP 2 : a new target for pro-senescence cancer therapies (2015) (0)
79: WNT16B, a new biomarker of senescent cells in vitro and in vivo, is necessary for the p53-dependent activation of p21WAF1 in cellular senescence (2010) (0)

This paper list is powered by the following services:

What Schools Are Affiliated With Manuel Serrano?

Manuel Serrano is affiliated with the following schools:

Manuel Serrano's Academic­Influence.com Rankings